Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research
Oesophageal perforation by migrated Ryles tube
Trop Doct. 2024 Apr 2:494755241241832. doi: 10.1177/00494755241241832. Online ahead of print.ABSTRACTA 72-year woman with a history of multiple cerebrovascular accidents presented with severe epigastric pain. An oesophageal perforation by the tip of a Ryles tube, which had migrated into the mediastinum, was diagnosed by radiography. An attempt at pushing the nasogastric tube into the stomach resulted in increasing the rupture to about 6 cm in size. Replacement by a triple-lumen nasojejunal feeding tube and subsequent feeding with c.1,400 calories per day enabled the perforation to close without further intervention.PMID:38...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amol Vadgaonkar Nagesh Kamat Sanil Parekh Gaurav Patil Ankit Dalal Amit Maydeo Source Type: research
Defunctioning ileostomy for typhoid ileal perforations: Out of the frying pan into the fire?
Trop Doct. 2024 Apr 2:494755241241830. doi: 10.1177/00494755241241830. Online ahead of print.ABSTRACTTyphoid ileal perforation (TIP) is a common surgical emergency in low-middle income countries (LMICs). Its high surgical morbidity and mortality is due to its often late presentation or diagnosis, the patient's malnutrition, severe peritoneal contamination and unavailability of intensive care in most peripheral hospitals. This prompted the philosophy of minimizing the crisis by avoiding any repair or anastomosis, limiting the surgery in these physiologically compromised patients and performing only a temporary defunctioning...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amrendra Verma Reena Kothari Arpan Mishra Pawan Agrawal Dhananjaya Sharma Source Type: research
Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research
Oesophageal perforation by migrated Ryles tube
Trop Doct. 2024 Apr 2:494755241241832. doi: 10.1177/00494755241241832. Online ahead of print.ABSTRACTA 72-year woman with a history of multiple cerebrovascular accidents presented with severe epigastric pain. An oesophageal perforation by the tip of a Ryles tube, which had migrated into the mediastinum, was diagnosed by radiography. An attempt at pushing the nasogastric tube into the stomach resulted in increasing the rupture to about 6 cm in size. Replacement by a triple-lumen nasojejunal feeding tube and subsequent feeding with c.1,400 calories per day enabled the perforation to close without further intervention.PMID:38...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amol Vadgaonkar Nagesh Kamat Sanil Parekh Gaurav Patil Ankit Dalal Amit Maydeo Source Type: research
Defunctioning ileostomy for typhoid ileal perforations: Out of the frying pan into the fire?
Trop Doct. 2024 Apr 2:494755241241830. doi: 10.1177/00494755241241830. Online ahead of print.ABSTRACTTyphoid ileal perforation (TIP) is a common surgical emergency in low-middle income countries (LMICs). Its high surgical morbidity and mortality is due to its often late presentation or diagnosis, the patient's malnutrition, severe peritoneal contamination and unavailability of intensive care in most peripheral hospitals. This prompted the philosophy of minimizing the crisis by avoiding any repair or anastomosis, limiting the surgery in these physiologically compromised patients and performing only a temporary defunctioning...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amrendra Verma Reena Kothari Arpan Mishra Pawan Agrawal Dhananjaya Sharma Source Type: research
Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research
Oesophageal perforation by migrated Ryles tube
Trop Doct. 2024 Apr 2:494755241241832. doi: 10.1177/00494755241241832. Online ahead of print.ABSTRACTA 72-year woman with a history of multiple cerebrovascular accidents presented with severe epigastric pain. An oesophageal perforation by the tip of a Ryles tube, which had migrated into the mediastinum, was diagnosed by radiography. An attempt at pushing the nasogastric tube into the stomach resulted in increasing the rupture to about 6 cm in size. Replacement by a triple-lumen nasojejunal feeding tube and subsequent feeding with c.1,400 calories per day enabled the perforation to close without further intervention.PMID:38...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amol Vadgaonkar Nagesh Kamat Sanil Parekh Gaurav Patil Ankit Dalal Amit Maydeo Source Type: research
Defunctioning ileostomy for typhoid ileal perforations: Out of the frying pan into the fire?
Trop Doct. 2024 Apr 2:494755241241830. doi: 10.1177/00494755241241830. Online ahead of print.ABSTRACTTyphoid ileal perforation (TIP) is a common surgical emergency in low-middle income countries (LMICs). Its high surgical morbidity and mortality is due to its often late presentation or diagnosis, the patient's malnutrition, severe peritoneal contamination and unavailability of intensive care in most peripheral hospitals. This prompted the philosophy of minimizing the crisis by avoiding any repair or anastomosis, limiting the surgery in these physiologically compromised patients and performing only a temporary defunctioning...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amrendra Verma Reena Kothari Arpan Mishra Pawan Agrawal Dhananjaya Sharma Source Type: research
Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research
Oesophageal perforation by migrated Ryles tube
Trop Doct. 2024 Apr 2:494755241241832. doi: 10.1177/00494755241241832. Online ahead of print.ABSTRACTA 72-year woman with a history of multiple cerebrovascular accidents presented with severe epigastric pain. An oesophageal perforation by the tip of a Ryles tube, which had migrated into the mediastinum, was diagnosed by radiography. An attempt at pushing the nasogastric tube into the stomach resulted in increasing the rupture to about 6 cm in size. Replacement by a triple-lumen nasojejunal feeding tube and subsequent feeding with c.1,400 calories per day enabled the perforation to close without further intervention.PMID:38...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amol Vadgaonkar Nagesh Kamat Sanil Parekh Gaurav Patil Ankit Dalal Amit Maydeo Source Type: research
Defunctioning ileostomy for typhoid ileal perforations: Out of the frying pan into the fire?
Trop Doct. 2024 Apr 2:494755241241830. doi: 10.1177/00494755241241830. Online ahead of print.ABSTRACTTyphoid ileal perforation (TIP) is a common surgical emergency in low-middle income countries (LMICs). Its high surgical morbidity and mortality is due to its often late presentation or diagnosis, the patient's malnutrition, severe peritoneal contamination and unavailability of intensive care in most peripheral hospitals. This prompted the philosophy of minimizing the crisis by avoiding any repair or anastomosis, limiting the surgery in these physiologically compromised patients and performing only a temporary defunctioning...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amrendra Verma Reena Kothari Arpan Mishra Pawan Agrawal Dhananjaya Sharma Source Type: research
Momentum of hope: The journey toward a universal TB vaccine
Trop Doct. 2024 Apr 2:494755241244833. doi: 10.1177/00494755241244833. Online ahead of print.ABSTRACTIn addressing the persistent threat of tuberculosis (TB) - a disease that claims millions of lives, especially in low-income countries - this correspondence underlines the critical role of advancing vaccine research. Historically, the BCG vaccine, developed over a century ago, has been the cornerstone of TB prevention. However, its efficacy is limited, particularly in adults and against pulmonary TB, the most common form of the disease. Recent developments, such as the M72/AS01E vaccine, demonstrate promising results in inc...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Bashar Haruna Gulumbe Aminu Shehu Source Type: research
Oesophageal perforation by migrated Ryles tube
Trop Doct. 2024 Apr 2:494755241241832. doi: 10.1177/00494755241241832. Online ahead of print.ABSTRACTA 72-year woman with a history of multiple cerebrovascular accidents presented with severe epigastric pain. An oesophageal perforation by the tip of a Ryles tube, which had migrated into the mediastinum, was diagnosed by radiography. An attempt at pushing the nasogastric tube into the stomach resulted in increasing the rupture to about 6 cm in size. Replacement by a triple-lumen nasojejunal feeding tube and subsequent feeding with c.1,400 calories per day enabled the perforation to close without further intervention.PMID:38...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amol Vadgaonkar Nagesh Kamat Sanil Parekh Gaurav Patil Ankit Dalal Amit Maydeo Source Type: research
Defunctioning ileostomy for typhoid ileal perforations: Out of the frying pan into the fire?
Trop Doct. 2024 Apr 2:494755241241830. doi: 10.1177/00494755241241830. Online ahead of print.ABSTRACTTyphoid ileal perforation (TIP) is a common surgical emergency in low-middle income countries (LMICs). Its high surgical morbidity and mortality is due to its often late presentation or diagnosis, the patient's malnutrition, severe peritoneal contamination and unavailability of intensive care in most peripheral hospitals. This prompted the philosophy of minimizing the crisis by avoiding any repair or anastomosis, limiting the surgery in these physiologically compromised patients and performing only a temporary defunctioning...
Source: Tropical Doctor - April 2, 2024 Category: Tropical Medicine Authors: Amrendra Verma Reena Kothari Arpan Mishra Pawan Agrawal Dhananjaya Sharma Source Type: research
