Frontal pyomucocoele as forehead swelling in a five-year-old girl.
We present the case of a five-year-old girl who presented with a frontal pyomucocoele requiring decompression and adequate antibiotics. PMID: 31311462 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - July 16, 2019 Category: Tropical Medicine Authors: Williams V, Iyer R, Reshma A, Jayashree M, Mohindra S, Verma S Tags: Trop Doct Source Type: research

Insulin resistance is not a risk factor for oesophageal varices development in hepatitis C.
Abstract Chronic hepatitis C (HCV) patients commonly have insulin resistance which is a risk factor for disease progression. Oesophageal varices may bleed with high mortality. We aimed to assess the relationship between insulin resistance and oesophageal varices. HCV-related compensated liver cirrhosis patients (n = 146) underwent gastroscopy and homeostasis model assessment (HOMA)-IR, HOMA-β and HOMA-S calculations. Their average age was 54.98 years; most (84.9%) patients were men and non-diabetic (60.3%). Patients with oesophageal varices had higher median Model for End-Stage Liver Disease (ME...
Source: Tropical Doctor - July 11, 2019 Category: Tropical Medicine Authors: Alsebaey A, Elhelbawy M Tags: Trop Doct Source Type: research

A sudden increase in occurrence of Salmonella Paratyphi A infection in Rourkela, western Odisha.
PMID: 31296149 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - July 11, 2019 Category: Tropical Medicine Authors: Bhattacharya SS, Satapathi S Tags: Trop Doct Source Type: research

Cartridge-based nucleic acid amplification test: a novel rapid diagnostic tool to study the burden of tuberculosis from a tertiary care hospital.
Abstract Despite efforts to limit the morbidity and mortality from tuberculosis (TB), it continues to be an important cause of death. There is an urgent need for a diagnostic test that accurately and quickly diagnoses TB, especially if it is also a near-point-of-care test. The GeneXpert polymerase chain reaction test (known in India as CBNAAT [cartridge-based nucleic acid amplification test] and is capable of diagnosing TB and rifampicin resistance within 2 h) is a promising tool. The duration of our study was two years and was carried out in the DOTS centre of a tertiary care hospital in India. A total of ...
Source: Tropical Doctor - July 10, 2019 Category: Tropical Medicine Authors: Kashyap B, Goyal N, Hyanki P, Singh NP, Khanna A Tags: Trop Doct Source Type: research

Involvement of the gallbladder in the course of viral hepatitis A in childhood.
Abstract The course of acute hepatitis A (AHA) in childhood is most often benign. There are relatively few reports of gallbladder involvement during such infection and its consequences. We discuss the cases of 75 children (mean age = 4.5 years) with confirmed AHA. Clinical and laboratory evaluation upon admission were classical for AHA. Only two children had normal bilirubin levels and 38.7% had visible involvement of the gallbladder with wall thickening of>3 mm, while six met criteria for acute acalculous cholecystitis. There appears to be no clear relationship between thickening of the ga...
Source: Tropical Doctor - June 27, 2019 Category: Tropical Medicine Authors: Velev V, Popov M, Tomov L, Golemanov B Tags: Trop Doct Source Type: research

Marked elevation of serum lipase in scrub typhus without pancreatitis: a report of three cases.
We report three cases of scrub typhus who presented with acute undifferentiated fever, where a marked elevation of serum lipase occurred without any evidence of acute pancreatitis, or other causes of elevated lipase levels. Scrub typhus should be considered as a cause of marked elevation of serum lipase, which can occur in the absence of pancreatitis. PMID: 31208290 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - June 18, 2019 Category: Tropical Medicine Authors: Bhargava A, Ali S, Rajeevan R, Udyavara R Tags: Trop Doct Source Type: research

Acquired diaphragmatic hernia in a preterm low birth weight neonate.
Abstract Iatrogenic diaphragmatic hernia is rare in children and we report a preterm low birth weight neonate with a presumably acquired diaphragmatic hernia due to trauma caused by treatment following pneumothorax. PMID: 31208291 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - June 18, 2019 Category: Tropical Medicine Authors: Captain M, Natu S, Parekh A, Naik A, Behera MK Tags: Trop Doct Source Type: research

Treatment of postscabies prurigo with diflucortolone and chlorquinaldol in a group of African refugees.
We present the results of a study on the effectiveness of a topical combination of diflucortolone and chlorquinaldol. Eighteen African patients who had been previously affected by scabies and treated with permethrin were enrolled. The diagnosis of PSP was made by excluding other causes through microscopic examinations. All patients were treated with the drug combination by two applications daily for two weeks. The primary study objective was to evaluate the itch by a visual analogue scale (VAS) of 0-100. Fifteen patients (83.3%) could be evaluated. All reported improvements: from 86/100 at the start to 29/100 (-57/100) at ...
Source: Tropical Doctor - June 18, 2019 Category: Tropical Medicine Authors: Veraldi S, Schianchi R, Esposito L, Pontini P, Nazzaro G Tags: Trop Doct Source Type: research

Epidemiological features of tularaemia in Central Anatolia, Turkey.
Abstract Tularaemia has become a public health threat in Turkey. Our aim was to examine the epidemiological characteristics of 154 tularaemia cases reported from Kayseri, Central Anatolia, between 2010 and 2017. Clinical diagnosis was confirmed by micro-agglutination test (≥1/160 titres). Most patients (56.5%) were residing in rural areas. The year with the highest case load was 2011 (40% of all cases). Tularaemia was reported in all seasons, but mostly in February (26.1%). Morbidity rates were higher in women and people aged ≥65 years. The tularaemia incidence in Kayseri was higher than in the whole country...
Source: Tropical Doctor - June 11, 2019 Category: Tropical Medicine Authors: Borlu A, Benli AR, Doganay M Tags: Trop Doct Source Type: research

Libman-Sacks endocarditis in a Bangladeshi patient suffering from rhupus.
We report such a patient, who had been diagnosed as having RA seven years before and had suffered an acute ischaemic stroke one year previously and had echocardiographic evidence of LSE found during routine evaluation. However, she tested negative for aPA. PMID: 31180802 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - June 10, 2019 Category: Tropical Medicine Authors: Zaman S, Rahim MA, Sayami LA, Nabi S, Islam AM, Ullah M Tags: Trop Doct Source Type: research

Factors associated with the resumption of sexual intercourse before the scheduled six-week postpartum visit.
Abstract This retrospective cohort study was aimed at evaluating the factors associated with the resumption of sexual intercourse (SI) before the six-week postpartum visit and was carried out between 1 January and 15 February 2014. The main variables studied included maternal age, number of living children, mode of delivery, complications observed at delivery and resumption or not of SI. Data from women who resumed SI were compared to those of women who did not. Fisher's exact test and t-test were used for comparison. We recruited 120 women, among whom 95 (79.1%) resumed SI. Of these, 65/95 (68.4%) did not attend ...
Source: Tropical Doctor - June 10, 2019 Category: Tropical Medicine Authors: Nkwabong E, Ilue EE, Nana Njamen T Tags: Trop Doct Source Type: research

Disseminated cutaneous chrysosporium infection.
We present an immunocompromised patient who presented with recurrent cutaneous abscesses. Histopathology of the abscess showed thick-walled conidia and septate fungal hyphae within the subcutis and fungal culture grew Chrysosporium species. PMID: 31179890 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - June 8, 2019 Category: Tropical Medicine Authors: Dincy PC, Meera T, Susanne PA, Promila RM Tags: Trop Doct Source Type: research

Diffuse cutaneous leishmaniasis with oral involvement in a patient of Northern Mexico.
We report a case of a 56-year-old Mexican woman exhibiting nodular lesions, plaques, crusts and scars involving the whole body. A solitary nodule was present at the junction between hard and soft palates. Diffuse cutaneous leishmaniasis is a disfiguring disease resulting in severe scarring if untreated. PMID: 31156067 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - June 2, 2019 Category: Tropical Medicine Authors: Mariz BALA, Sánchez-Romero C, Alvarado NAP, Campos EMM, Almeida OP, Martínez-Pedraza R Tags: Trop Doct Source Type: research

Paralytic rabies: An acute flaccid myelitis after inadequate post exposure prophylaxis.
Abstract Rabies has two distinct clinical syndromes, encephalitic (or 'furious') and paralytic (or 'dumb'). The paralytic form presents as acute flaccid myelitis and is more common in patients who received post-exposure anti-rabies vaccination without rabies immunoglobulins. We have recently had the opportunity to manage a middle-aged man presenting as 'dumb' paralytic rabies. PMID: 31132966 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - May 27, 2019 Category: Tropical Medicine Authors: Pannu AK, Kumar RV, Vijaykumar D, Priya L, Singh H, Bhalla A Tags: Trop Doct Source Type: research

Characteristics and outcomes in paediatric patients presenting with congenital colorectal diseases in sub-Saharan Africa.
Abstract In sub-Saharan Africa, there is a high burden of paediatric surgical conditions and a paucity of data regarding outcomes of congenital colorectal anomalies. A retrospective, descriptive analysis utilizing the Kamuzu Central Hospital (Lilongwe, Malawi) paediatric acute care surgery database (age ≤ 18 years) over 44 months was performed. Of the 133 children presenting, 82 had Hirschsprung disease (HD) (2.4 ± 2.7 years) and 51 had anorectal malformations (ARM) (1.8 ± 2.4 years). Of the latter, 51.0% underwent surgery, mainly exploratory laparotomy (n...
Source: Tropical Doctor - May 20, 2019 Category: Tropical Medicine Authors: Purcell L, Ngwira N, Gallaher J, Cairns B, Charles A Tags: Trop Doct Source Type: research

Seroprevalence of dengue in blood donors in an outbreak: experience of a blood bank in north India.
Abstract Our aim was to determine the prevalence of dengue among blood donors at a centre in north India during an outbreak. A retrospective cross-sectional study was conducted using stored serum samples of 369 blood donors at the All India Institute of Medical Sciences (AIIMS), Rishikesh between August and November 2016. Serum samples were tested by an immune-chromatographic rapid test for the screening of dengue markers (IgG/IgM and NS-1). We found prevalence rates of IgG and NS-1 to be 14.9 and 0.54%, respectively. PMID: 31088225 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - May 14, 2019 Category: Tropical Medicine Authors: Jain A, Jain S, Chowdhury N Tags: Trop Doct Source Type: research

Listeria meningitis in an immunocompetent child.
Abstract Listeria monocytogenes is a gram-positive, facultative anaerobic, motile bacillus widely spread in the environment. However, clinical infection in humans is uncommon. The route of infection is often through ingestion of raw vegetables, meat and unpasteurised dairy products. Listeria is an uncommon cause of meningitis in immunocompetent individuals, but it should be considered strongly in neonates and the elderly, and it should also be considered in those with impaired cell-mediated immunity. 1 , 2 Only a few case reports of invasive listeriosis in humans have been reported from India. 3 - 8 In our case, a...
Source: Tropical Doctor - May 13, 2019 Category: Tropical Medicine Authors: Gulla KM, Gupta D, Sachdev A Tags: Trop Doct Source Type: research

Torsion of ovarian endometrioma in pregnancy: a case report and review of the literature.
We report a 25-year-old primigravida in the eighth week of gestation presenting with acute onset lower abdominal pain. A pelvic ultrasonography showed an intrauterine single viable embryo with a right ovarian cyst measuring 6 × 6 cm in diameter. Exploratory laparotomy revealed torsion of the right adnexa by 360°. After a right adnexectomy was performed, the patient proceeded to full-term pregnancy. Adnexal torsion is defined as rotation of> 45° in the long axis of the adnexae. Its occurrence during gestation is reported as 2%, accounting for 2.7% of surgical emergencies in pregn...
Source: Tropical Doctor - May 8, 2019 Category: Tropical Medicine Authors: Hua D, Zhao P, Jiang L Tags: Trop Doct Source Type: research

Malaria today: advances in management and control.
Abstract Over the past two decades, malaria-related deaths have reduced substantially, especially in African children. However, the global malaria burden still remains high. The recent emergence of resistance to artemisinin, the backbone of malaria management, could threaten malaria control. Importantly, over the past five years, there has been an upsurge in research in the development of novel antimalarial drugs (and combinations), malaria vaccine and new vector-control strategies that can boost the malaria control programme. PMID: 31060446 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - May 6, 2019 Category: Tropical Medicine Authors: Pannu AK Tags: Trop Doct Source Type: research

The influence of illness duration before diagnosis on clinical characteristics and outcome in human brucellosis.
Abstract Our study assesses the influence of illness duration before establishing the diagnosis of brucellosis and initiating therapy on patients' main clinical characteristics and outcome in an endemic area. The medical files of 297 patients with brucellosis were retrospectively analysed. They were divided into four groups according to illness duration before initiating therapy: 90 days. There were significant differences in the occurrences of fever ( P = 0.019), focal forms ( P = 0.026), spondylitis ( P = 0.034) and therapeutic failures ( P = 0.006) between...
Source: Tropical Doctor - May 6, 2019 Category: Tropical Medicine Authors: Bosilkovski M, Siskova D, Spasovska K, Vidinic I, Dimzova M Tags: Trop Doct Source Type: research

Systematic review of Lyme disease in Turkey.
şat Sipahi O Abstract A systematic review was conducted with the aim of describing the demographical data, features and outcomes of patients with Lyme disease (LD), reported from Turkey. Three international database (electronic PubMed, Web of Science and Scopus) and two national database (Ulakbim and Turkmedline) searches were performed using the following keywords (['Lyme' or 'Borrelia burgdorferi' or 'Borrelia' or 'Borreliosis'] and 'Turkey [and/country]'). National Notifiable Diseases Surveillance System (NNNDS) of Centers for Disease Control and Prevention (CDC) criteria were used for classification. A PRISMA...
Source: Tropical Doctor - April 24, 2019 Category: Tropical Medicine Authors: Önal U, Aytaç Erdem H, Uyan Önal A, Reşat Sipahi O Tags: Trop Doct Source Type: research

Chikungunya-induced inflammatory myositis: a case report in India.
We report a 35-year-old woman with quadriplegia caused by chikungunya-induced inflammatory myositis. The diagnosis was confirmed with clinical examination, electromyography study, muscle biopsy findings and exclusion of other causes. There have been case reports of inflammatory myositis in association with various infections as well as in association with other neurological presentations in chikungunya. However, this may be the first case report of isolated inflammatory myositis associated with chikungunya fever. PMID: 31018774 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - April 24, 2019 Category: Tropical Medicine Authors: Dev N, Kumar R, Gogna A, Sharma S Tags: Trop Doct Source Type: research

Should UK specialty trainee doctors in Obstetrics and Gynaecology have more opportunities to work in global women's health?
Abstract The Royal College of Obstetricians and Gynaecologists (RCOG) has a long history of advocacy for women's health, nationally and internationally. There is a demand and interest in global women's health among a sample of junior doctors training in obstetrics and gynaecology in the UK. There is ongoing debate regarding whether this desire should be nurtured, opportunities created and barriers addressed, both in the interest of training and as a means of addressing global health inequity. Global health work needs to be a mutually beneficial partnership for all involved, with work carried out sensitively and su...
Source: Tropical Doctor - April 24, 2019 Category: Tropical Medicine Authors: McCauley M, Unger HW, Vousden N, Sobhy S Tags: Trop Doct Source Type: research

Physician burnout: an acute issue for the medical community in low- and middle-income countries.
PMID: 31014194 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - April 23, 2019 Category: Tropical Medicine Authors: Majid Z, Warsi SM Tags: Trop Doct Source Type: research

Topical timolol treatment for periocular infantile haemangioma in the developing world.
We present a case of a segmental infantile haemangioma with periocular involvement impacting on early visual development which was successfully treated with topical timolol maleate 0.5% drops in the developing world. PMID: 31014195 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - April 23, 2019 Category: Tropical Medicine Authors: Jefferson RJ, Hildebrand GD Tags: Trop Doct Source Type: research

Rationale in diagnosis and management: role of screening and history taking.
PMID: 30997867 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - April 18, 2019 Category: Tropical Medicine Authors: Venkatesan S, Thangaraju P Tags: Trop Doct Source Type: research

Clinical null hypothesis: Fisher revisited.
PMID: 30991906 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - April 16, 2019 Category: Tropical Medicine Authors: Sreeharan N Tags: Trop Doct Source Type: research

Switching to secukinumab in difficult-to-treat psoriasis recalcitrant to methotrexate, cyclosporine and leflunomide, in a tuberculosis-endemic country.
Abstract Several biological agents have been approved for the treatment of recalcitrant psoriasis. However, there is a lack of a consensus algorithm guiding the drug selection for patients who have failed conventional drugs. In cases not improving with cyclosporine, direct switching to a biological therapy usually leads to a disease flare owing to increased production of interleukin (IL)-17A. Thus, secukinumab, a rapidly acting anti-IL-17A drug, may be ideal in such situations. PMID: 30967096 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - April 9, 2019 Category: Tropical Medicine Authors: Gupta A, Sardana K, Gautam RK Tags: Trop Doct Source Type: research

Revisiting ABO incompatibility as a risk factor for significant neonatal hyperbilirubinemia.
Abstract Babies with ABO incompatibility are often advised frequent biochemical screening and prolonged hospital stay. Our primary objective of the study was to compare serum bilirubin levels at 48 h and 96 h of age in neonates with and without ABO incompatibility. Our prospective study included neonates with gestation ≥ 34 weeks, with or without ABO incompatibility (92 in each group). A direct Coombs test was performed on cord blood. The mean serum bilirubin and haematocrit levels in both groups at 48 h and 96 h were comparable. The mean reticulocyte count of babies wi...
Source: Tropical Doctor - April 3, 2019 Category: Tropical Medicine Authors: Khurana R, Batra P, Faridi M, Khan N Tags: Trop Doct Source Type: research

The relation of toddy (palm wine) intake to amoebic liver abscess in a predominantly toddy-drinking population: a cross-sectional study.
Abstract The role of toddy (palm wine) as an independent risk factor for amoebic liver abscess (ALA) is not clear. In a cross-sectional study, the clinico-demographic profiles of inpatients with ALA were examined. Microscopy examination of toddy (n = 43) samples was performed. A total of 198 patients with ALA were enrolled, most of whom were: admitted during the May-August months (48%); chronic alcoholic (85% [70% toddy]); malnourished (85%); and of low socioeconomic status (88%). Clinical and laboratory parameters were comparable between toddy and distilled alcohol drinkers. None of the toddy sample...
Source: Tropical Doctor - April 2, 2019 Category: Tropical Medicine Authors: Kumar Jha A, Jha P, Chaudhary M, Kumar S, Prakash V, Mohan Dayal V Tags: Trop Doct Source Type: research

Doctors and Torture.
PMID: 30917771 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 27, 2019 Category: Tropical Medicine Authors: Cotton M Tags: Trop Doct Source Type: research

The brutality of the Sudanese government against doctors is determined by policy rather than isolated events.
PMID: 30898046 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 21, 2019 Category: Tropical Medicine Authors: Mahmoud O Tags: Trop Doct Source Type: research

Parotitis coexisting with Kawasaki disease in a child: a rare presentation of Kawasaki disease.
We report such a case in a five-year-old. PMID: 30898051 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 21, 2019 Category: Tropical Medicine Authors: Gökçe Ş, Uysal N, Erkmen H, Doğan E, Koç F Tags: Trop Doct Source Type: research

Perinatal transmission of dengue infection in a preterm neonate: a case report.
We present an interesting case of dengue infection in a preterm neonate managed at our unit. PMID: 30898052 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 21, 2019 Category: Tropical Medicine Authors: Jain J, V L, R S Tags: Trop Doct Source Type: research

Osteopetrosis: presenting as maxillary osteomyelitis.
Abstract Osteopetrosis is a rare congenital disease presenting with recurrent fractures, hematopoietic insufficiency and hepatosplenomegaly. Though osteomyelitis is a known complication in osteopetrosis, osteopetrosis presenting as osteomyelitis is rare. Management consists of multidisciplinary approach for complications and bone marrow transplant for the infantile form of disease. PMID: 30895884 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 21, 2019 Category: Tropical Medicine Authors: Gupta S, Kumar R, Agrawal A Tags: Trop Doct Source Type: research

Brucellosis after dengue.
Abstract Zoonoses such as Brucella, Mycobacterium bovis, Campylobacter, Salmonella, Escherichia coli, Listeria, etc. are spread by ingestion of contaminated unpasteurised milk products (from infected cattle) and result in infectious outbreaks, hospitalisations and mortality. In Southeast Asian countries, raw goat's milk is sometimes used for dengue infection-associated thrombocytopenia; however, evidence to support this sociocultural practice is lacking. A peak incidence of brucellosis cases may occur after a dengue season in communities where this practice is prevalent. PMID: 30895885 [PubMed - as supplied b...
Source: Tropical Doctor - March 21, 2019 Category: Tropical Medicine Authors: Pannu AK, Pannu S Tags: Trop Doct Source Type: research

Atypical clinical presentation of visceral leishmaniasis: a rare case without splenomegaly.
We report a case of a woman from an endemic area with fever but normal splenic size. This is rare, especially in patients not immunocompromised. PMID: 30895886 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 21, 2019 Category: Tropical Medicine Authors: Cunha MA, Antunes AG, Eufrasio de Azevedo MM, Rafael Maciel JF, Lacerda HG Tags: Trop Doct Source Type: research

Guillain-Barre syndrome: a rare complication of leptospirosis and scrub typhus co-infection.
We report a 20-year-old man with GBS associated with concurrent leptospirosis and scrub typhus infection. GBS was confirmed with clinical examination and nerve conduction studies. There have been case reports of GBS in association with Leptospira and Orienta tsusugamushi separately. However, this may be the first case report of GBS associated with concurrent diseases. PMID: 30895887 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 21, 2019 Category: Tropical Medicine Authors: Dev N, Kumar R, Kumar D Tags: Trop Doct Source Type: research

Microfilaria: not always associated with eosinophilia.
Abstract Filariasis is a parasitic infection seen predominantly in tropical and subtropical countries including India. In clinically suspected cases, examining a thick wet mount smear or a buffy coat film is most informative. In unsuspected cases, however, eosinophilia in a peripheral blood smear (PBS) may be the sole indicator of parasitaemia. A few cases of tissue microfilaria with the absence of peripheral blood eosinophilia (PBE) have been reported. Here, we report two cases of microfilaria in PBS in the absence of PBE. A routine screening of the tail end of all PBS at low power magnification is also advised a...
Source: Tropical Doctor - March 21, 2019 Category: Tropical Medicine Authors: Garg N, More S, Sharma M, Kotru M Tags: Trop Doct Source Type: research

Irritable bowel syndrome in Egyptian patients: plausible risk factors and association with intestinal protozoa.
Abstract The pathogenesis of irritable bowel syndrome (IBS) is not yet clear. Our study suggested parasitic infection and other plausible risk factors among Egyptian IBS patients. We studied 40 IBS patients diagnosed according to Rome III criteria (Group I), 40 with other gastrointestinal symptoms (Group II) and 40 healthy controls (Group III). Stool samples were examined using direct wet smear, sedimentation technique, trichrome stain and immune-chromatographic tests for Cryptosporidium parvum. IBS patients displayed a significantly greater percentage of Blastocystis hominis infection (45%) than non-IBS patients ...
Source: Tropical Doctor - March 18, 2019 Category: Tropical Medicine Authors: Salem AI, El-Taweel HA, Madkour MA, Abd El-Latif NF, Abd-Elrazeq ES Tags: Trop Doct Source Type: research

Granulomatous inflammation still fooling surgeons.
PMID: 30885055 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 18, 2019 Category: Tropical Medicine Authors: Durgapal P, Joshi PP, Gupta A, Gupta A, Kishore S, Singh A Tags: Trop Doct Source Type: research

Successful treatment of XDR-TB patient in Tanzania: report of the first XDR-TB patient.
We present the first case with confirmed extensive drug-resistant TB in Tanzania in a patient who had prior exposure to anti-TB drugs and a history of imprisonment in South Africa. The addition of bedaquiline to the treatment regime resulted in positive to negative sputum conversion. After a total of 30 months on treatment he was declared cured, remaining clinically stable and culture-negative throughout the follow-up. Close monitoring is important in managing drug-resistant TB cases, and good surveillance is required to detect drug-resistant TB to prevent further transmission. PMID: 30885056 [PubMed - as supplied by ...
Source: Tropical Doctor - March 18, 2019 Category: Tropical Medicine Authors: Lyakurwa D, Lyimo J, Mleoh L, Riziki K, Lupinda M, Mpondo BC Tags: Trop Doct Source Type: research

The burden and risk factors for postnatal depression and depressive symptomatology among women in Kampala.
Abstract Major depressive disorder (MDD) is a major global health challenge and postnatal women may be at an increased risk for this disorder. Very few studies have tested this hypothesis in sub-Saharan Africa (SSA), so it is uncertain whether risk factors implicated elsewhere in the world are relevant in SSA. We explored prevalence and risk factors for MDD and depressive symptomatology among postnatal mothers in Kampala. Three hundred postnatal mothers at Nsambya Hospital were assessed for MDD using the DSM IV-based MINI; prevalence and risk factors were determined using frequencies and regressions, respectively....
Source: Tropical Doctor - March 18, 2019 Category: Tropical Medicine Authors: Nampijja M, Natamba B, Mpango R, Kinyanda E Tags: Trop Doct Source Type: research

Hepatitis A infection related haemophagocytic syndrome: a case report and systematic review.
We report an unusual case of haemophagocytosis associated with hepatitis A virus (HAV) infection in a 21-year-old man. This was further complicated by haemolysis secondary to G-6-PD deficiency and fungal sepsis. Our patient was treated successfully with intravenous immunoglobulin (IVIg) and supportive care. A systematic review of all reported cases of HAV associated haemophagocytosis is presented. PMID: 30871416 [PubMed - as supplied by publisher] (Source: Tropical Doctor)
Source: Tropical Doctor - March 14, 2019 Category: Tropical Medicine Authors: Mallick B, Daniel P, Dutta U Tags: Trop Doct Source Type: research

Reliability of coeliac serology in monitoring dietary adherence in children with coeliac disease on a gluten-free diet.
This study aimed to determine the utility of coeliac serology for monitoring dietary adherence in coeliac disease. Serum anti-tTg IgA and anti-DGP IgG levels of 42 newly diagnosed patients were measured at diagnosis and at intervals of three, six and 12 months after starting a gluten-free diet. Both anti-tTg and anti-DGP antibodies decreased in all patients. The decline in the former was significantly greater at 3-12 months throughout, while in the latter the decline was seen only at three months but not subsequently. Serial measurement of coeliac serology may help in monitoring adherence to a gluten-free diet. PMID: ...
Source: Tropical Doctor - March 14, 2019 Category: Tropical Medicine Authors: Jain R, Kumar P, Kapoor S, Basu S, Lomash A, Rohatgi S Tags: Trop Doct Source Type: research

Acquired heart disease in children is not necessarily rheumatic.
Abstract Acquired heart diseases (AHD) cause significant morbidity and mortality in children. There are limited studies on their burden in children. We conducted a retrospective study of 85 consecutive children diagnosed with AHD using clinical evaluation and echocardiography at Medical College, Kanpur, India to determine the aetiology and outcome of AHD in children. We found rheumatic heart disease (RHD) in one-third, cardiomyopathies or myocarditis combined in a further third and the remaining third were other causes, including pericardial diseases and metabolic or genetic disorders. These latter diseases were f...
Source: Tropical Doctor - March 13, 2019 Category: Tropical Medicine Authors: Agarwal N, Taneja S Tags: Trop Doct Source Type: research

Maxillary myxoma misdiagnosed as tuberculosis.
We present here the case of a three-year-old girl with a maxillary myxoma misdiagnosed as tuberculosis (TB). She was referred to our TB clinic with fever for seven months and swelling of the left cheek and a positive Mantoux test. Her mother was also on treatment for TB lymphadenitis. The child had been commenced on anti-tuberculous therapy (ATT) two months before, and because of its unusual location of the swelling, we did a Caldwell-Luc procedure and a white gelatinous tissue was obtained which, on histopathological examination, revealed myxomatous tissue and no granulomas. TB culture was negative. The patient was then r...
Source: Tropical Doctor - February 25, 2019 Category: Tropical Medicine Authors: Gandhi D, Pawar V, Chandane P, Shah I Tags: Trop Doct Source Type: research

Urinary neutrophil gelatinase-associated lipocalin for diagnosis of spontaneous bacterial peritonitis.
Abstract Cirrhotic patients with ascites are at high risk of developing spontaneous bacterial peritonitis (SBP). After exclusion of patients with acute kidney injury (AKI) or other infections, urinary neutrophil gelatinase-associated lipocalin (NGAL) levels were compared between two matched groups of Egyptian cirrhotic patients with ascites, mostly secondary to hepatitis C infection (98%). Group 1 had SBP (n = 41) and group 2 did not (n = 45). By univariate analysis, urinary-NGAL, high total bilirubin, serum creatinine, international normalised ratio and the Model of End-Stage Liver Dis...
Source: Tropical Doctor - February 20, 2019 Category: Tropical Medicine Authors: Fouad TR, Abdelsameea E, Elsabaawy M, Ashraf Eljaky M, Zaki El-Shenawy S, Omar N Tags: Trop Doct Source Type: research

An uncommon case of gall bladder mass: gall bladder tuberculosis.
Abstract Gall bladder tuberculosis (TB) is a rare entity and differentiation of gall bladder TB from gall bladder malignancy is difficult. We hereby present an unusual case of incidental diagnosis of gall bladder TB during the evaluation of a gall bladder with suspicion of gall bladder cancer in a 49-year-old woman. The diagnosis of gall bladder TB was made with fine needle aspiration cytology (FNAC) from the gall bladder mass as the disease was found unresectable after cross-sectional imaging. Even with the advancement of cross-sectional imaging, the differentiation of gall bladder TB from gall bladder malignancy...
Source: Tropical Doctor - February 19, 2019 Category: Tropical Medicine Authors: Deo KB, Sharma V, Mandavdhare H, Kumar Basher R, Rohilla M, Singh H Tags: Trop Doct Source Type: research

Unique temperature patterns in 24-h continuous tympanic temperature in tuberculosis.
Abstract Body temperature monitoring in most healthcare institutions is limited to checking the presence or absence of fever. Our present study evaluated the 24h continuous tympanic temperature pattern in patients with fever in order to detect typical patterns seen in tuberculosis (TB). This observational study was conducted on 81 undifferentiated fever patients whose recordings were stored using the TherCom device. Unique temperature patterns were analysed and compared. TB patients exhibited a unique temperature pattern, namely a slow temperature elevation followed by slow temperature fall seen in 78.5% (22/28) c...
Source: Tropical Doctor - February 19, 2019 Category: Tropical Medicine Authors: Dakappa PH, Rao SB, B G, Bhat GK, Mahabala C Tags: Trop Doct Source Type: research