Aetiology and risk factors of community‐acquired pneumonia in hospitalized patients in Norway
ConclusionOur results indicate that S. pneumoniae is the most common bacterial cause of pneumonia in hospitalized patients, and the prevalence of Legionella pneumonia is probably higher in Norway than recognized previously. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 6, 2015 Category: Respiratory Medicine Authors: Wenche Røysted, Øystein Simonsen, Andrew Jenkins, Marjut Sarjomaa, Martin Veel Svendsen, Eivind Ragnhildstveit, Yngvar Tveten, Anita Kanestrøm, Halfrid Waage, Jetmund Ringstad Tags: Original Article Source Type: research
Aetiology and risk factors of community ‐acquired pneumonia in hospitalized patients in Norway
ConclusionOur results indicate that S. pneumoniae is the most common bacterial cause of pneumonia in hospitalized patients, and the prevalence of Legionella pneumonia is probably higher in Norway than recognized previously. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 5, 2015 Category: Respiratory Medicine Authors: Wenche R øysted, Øystein Simonsen, Andrew Jenkins, Marjut Sarjomaa, Martin Veel Svendsen, Eivind Ragnhildstveit, Yngvar Tveten, Anita Kanestrøm, Halfrid Waage, Jetmund Ringstad Tags: ORIGINAL ARTICLE Source Type: research
Outcome of community-acquired pneumonia with cardiac complications
Conclusions Cardiac complications are common in the admitted patients with pneumonia and they are associated with increased pneumonia severity and increased cardiovascular risk, these complications adds to the risk of mortality, so optimal management of these events may reduce the burden of death associated with this infection. (Source: Egyptian Journal of Chest Diseases and Tuberculosis)
Source: Egyptian Journal of Chest Diseases and Tuberculosis - March 22, 2015 Category: Respiratory Medicine Source Type: research
Chlamydophila psittaci-negative ocular adnexal marginal zone lymphomas express self polyreactive B-cell receptors
Fredricks & I S Lossos (Source: Leukemia)
Source: Leukemia - March 20, 2015 Category: Hematology Authors: D ZhuS BhattX LuF GuoH VeelkenD K HsuF-T LiuS Alvarez CubelaK KunkallaF VegaJ R Chapman-FredricksI S Lossos Source Type: research
The aetiology of community associated pneumonia in children in Nanjing, China and aetiological patterns associated with age and season.
CONCLUSIONS: The results show there were 4 main viral and atypical bacterial pathogens causing CAP in our study. Some pathogens were found to be associated with age and season. M. pneumoniae was the most predominant pathogen among these 9 pathogens. It is necessary to take preventative measures in order to prevent the spread of these pathogens in susceptible age groups during peak season.
PMID: 25778142 [PubMed - in process] (Source: Adv Data)
Source: Adv Data - March 19, 2015 Category: Epidemiology Authors: Chen K, Jia R, Li L, Yang C, Shi Y Tags: BMC Public Health Source Type: research
Etiology and risk factors of community‐acquired pneumonia in hospitalized patients in Norway
ConclusionOur results indicate that S. pneumoniae is the most common bacterial cause of pneumonia in hospitalized patients, and the prevalence of Legionella pneumonia is probably higher in Norway than recognized previously. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 12, 2015 Category: Respiratory Medicine Authors: Wenche Røysted, Øystein Simonsen, Andrew Jenkins, Marjut Sarjomaa, Martin Veel Svendsen, Eivind Ragnhildstveit, Yngvar Tveten, Anita Kanestrøm, Halfrid Waage, Jetmund Ringstad Tags: Original Article Source Type: research
Enzymatic characterization of Chlamydophila pneumoniae phospholipase D.
Authors: Mancini F, Ciervo A
Abstract
Chlamydophila pneumoniae, an aetiological agent of respiratory infection, is also thought to play an immuno-pathogenetic role in atherosclerosis by contributing to inflammation and plaque instability. Phospholipase D (PLD) is an enzyme involved in lipid metabolism and may have a direct or indirect impact on virulence and the inflammatory response. Some aspects of the developmental cycle of C. pneumoniae suggest a direct implication of its PLD (CpPLD) in the pathogenesis, specifically by affecting the regulation of lipid metabolism and lipid exchange between C. pneumoni...
Source: New Microbiologica - March 7, 2015 Category: Microbiology Tags: New Microbiol Source Type: research
Long-term outcomes of first-line treatment with doxycycline in patients with previously untreated ocular adnexal marginal zone B cell lymphoma
In conclusion, first-line doxycycline therapy was effective and safe. Patients who failed to respond to doxycycline therapy were successfully salvaged with chemotherapy and/or radiotherapy without compromising long-term outcomes. Patients with T1N0M0 disease could be considered good candidates for first-line doxycycline. (Source: Annals of Hematology)
Source: Annals of Hematology - March 5, 2015 Category: Hematology Source Type: research
Detection of Chlamydophila Pneumoniae and Typical Bacteria in Patients with Chronic Cough.
Authors: Jama-Kmiecik A, Frej-Madrzak M, Gosciniak G, Sarowska J, Choroszy-Krol I
Abstract
The aim of research was to analyze the results of microbiological tests for typical and atypical bacteria in patients with symptoms of chronic cough. A total of 214 outpatients aged from 2 to 94 years (110 women, 64 men, and 40 children) with chronic cough were studied. Four hundred twenty eight throat swabs were examined for atypical bacteria antigen (Chlamydophila pneumoniae) (n = 214) and typical pathogens (n = 214). Chl. pneumoniae detection was performed using indirect immunofluorescence test. Classical...
Source: Advances in Experimental Medicine and Biology - March 2, 2015 Category: Research Tags: Adv Exp Med Biol Source Type: research
Etiology of community-acquired pneumonia and diagnostic yields of microbiological methods: a 3-year prospective study in Norway
Background:
Despite recent advances in microbiological techniques, the etiology of community-acquired pneumonia (CAP) is still not well described. We applied polymerase chain reaction (PCR) and conventional methods to describe etiology of CAP in hospitalized adults and evaluated their respective diagnostic yields.
Methods:
267 CAP patients were enrolled consecutively over our 3-year prospective study. Conventional methods (i.e., bacterial cultures, urinary antigen assays, serology) were combined with nasopharyngeal (NP) and oropharyngeal (OP) swab samples analyzed by real-time quantitative PCR (qPCR) for Streptococcus pneu...
Source: BMC Infectious Diseases - February 15, 2015 Category: Infectious Diseases Authors: Jan HolterFredrik MüllerOla BjørangHelvi SamdalJon MarthinsenPål JenumThor UelandStig FrølandPål AukrustEinar HusebyeLars Heggelund Source Type: research
Management of the marginal zone lymphomas.
Abstract
Marginal zone lymphomas (MZL) represent around 8 % of all non-Hodgkin lymphomas. During the last decades a number of studies have addressed the mechanisms underlying the disease development. Extranodal MZL lymphoma usually arises in mucosal sites where lymphocytes are not normally present from a background of either autoimmune processes, such as Hashimoto thyroiditis or Sjögren syndrome or chronic infectious conditions. In the context of a persistent antigenic stimulation, successive genetic abnormalities can progressively hit a B-cell clone among the reactive B-cells of the chronic inflammatory ...
Source: Cancer Control - February 8, 2015 Category: Cancer & Oncology Authors: Vannata B, Stathis A, Zucca E Tags: Cancer Treat Res Source Type: research
Cross-species transmission and emergence of novel viruses from birds
Publication date: February 2015 Source:Current Opinion in Virology, Volume 10 Author(s): Jasper Fuk-Woo Chan , Kelvin Kai-Wang To , Honglin Chen , Kwok-Yung Yuen Birds, the only living member of the Dinosauria clade, are flying warm-blooded vertebrates displaying high species biodiversity, roosting and migratory behavior, and a unique adaptive immune system. Birds provide the natural reservoir for numerous viral species and therefore gene source for evolution, emergence and dissemination of novel viruses. The intrusions of human into natural habitats of wild birds, the domestication of wild birds as pets or racing ...
Source: Current Opinion in Virology - February 4, 2015 Category: Virology Source Type: research
Erythema multiforme associated with Chlamydophila pneumoniae infection: a report of two cases and a mini‐literature review
(Source: The Journal of Dermatology)
Source: The Journal of Dermatology - January 9, 2015 Category: Dermatology Authors: Takahiro Sawada, Mitsuhiro Suehiro Tags: Letter to the Editor Source Type: research
Emendation of the family Chlamydiaceae: Proposal of a single genus, Chlamydia, to include all currently recognized species.
Abstract
The family Chlamydiaceae (order Chlamydiales, phylum Chlamydiae) comprises important, obligate intracellular bacterial pathogens of humans and animals. Subdivision of the family into the two genera Chlamydia and Chlamydophila has been discussed controversially during the past decade. Here, we have revisited the current classification in the light of recent genomic data and in the context of the unique biological properties of these microorganisms. We conclude that neither generally used 16S rRNA sequence identity cut-off values nor parameters based on genomic similarity consistently separate the t...
Source: Systematic and Applied Microbiology - January 8, 2015 Category: Microbiology Authors: Sachse K, Bavoil PM, Kaltenboeck B, Stephens RS, Kuo CC, Rosselló-Móra R, Horn M Tags: Syst Appl Microbiol Source Type: research
Lack of effectiveness of the 23-valent polysaccharide pneumococcal vaccine in reducing all-cause pneumonias among healthy young military recruits: A randomized, double-blind, placebo-controlled trial.
CONCLUSIONS: Data from this large, double-blind, placebo controlled trial do not support routine use of PPV23 among healthy new military trainees. This clinical trial was registered at clinicaltrials.gov (registration number NCT02079701, http://www.clinicaltrials.gov/ct2/show/NCT02079701?term=NCT02079701&rank=1).
PMID: 25579777 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - January 8, 2015 Category: Allergy & Immunology Authors: Russell KL, Baker CI, Hansen C, Poland GA, Ryan MA, Merrill MM, Gray GC Tags: Vaccine Source Type: research
