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Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells
Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells, Published online: 12 December 2017; doi:10.1038/leu.2017.349Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells (Source: Leukemia)
Source: Leukemia - December 12, 2017 Category: Hematology Authors: P Casado E H Wilkes F Miraki-Moud M M Hadi A Rio-Machin V Rajeeve R Pike S Iqbal S Marfa N Lea S Best J Gribben J Fitzgibbon P R Cutillas Source Type: research

Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol
Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol, Published online: 06 December 2017; doi:10.1038/leu.2017.279Outcome of relapsed infant acute lymphoblastic leukemia treated on the interfant-99 protocol (Source: Leukemia)
Source: Leukemia - December 6, 2017 Category: Hematology Authors: E M C Driessen P de Lorenzo M Campbell M Felice A Ferster I Hann A Vora L Hovi G Escherich C K Li G Mann T Leblanc F Locatelli A Biondi J Rubnitz M Schrappe L Silverman J Stary R Suppiah T Szczepanski M Valsecchi R Pieters Source Type: research

Rethinking JAK2 inhibition: towards novel strategies of more specific and versatile Janus kinase inhibition
Rethinking JAK2 inhibition: towards novel strategies of more specific and versatile Janus kinase inhibition, Published online: 06 December 2017; doi:10.1038/leu.2017.158Rethinking JAK2 inhibition: towards novel strategies of more specific and versatile Janus kinase inhibition (Source: Leukemia)
Source: Leukemia - December 6, 2017 Category: Hematology Authors: E Leroy S N Constantinescu Source Type: research

The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemiaAG Sanarico et al
The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemiaAG Sanarico et al, Published online: 06 December 2017; doi:10.1038/leu.2017.342The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemiaAG Sanarico et al (Source: Leukemia)
Source: Leukemia - December 6, 2017 Category: Hematology Authors: A G Sanarico C Ronchini A Croce E M Memmi U A Cammarata A De Antoni S Lavorgna M Divona L Giac ò G E M Melloni A Brendolan G Simonetti G Martinelli P Mancuso F Bertolini F L Coco G Melino P G Pelicci F Bernassola Source Type: research

Targeting MYC in multiple myeloma
Targeting MYC in multiple myeloma, Published online: 06 December 2017; doi:10.1038/leu.2017.347Targeting MYC in multiple myeloma (Source: Leukemia)
Source: Leukemia - December 6, 2017 Category: Hematology Authors: K K Jovanovi ć C Roche-Lestienne I M Ghobrial T Facon B Quesnel S Manier Source Type: research

CRISPR/Cas9 edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC
CRISPR/Cas9 edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC, Published online: 06 December 2017; doi:10.1038/leu.2017.346CRISPR/Cas9 edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC (Source: Leukemia)
Source: Leukemia - December 6, 2017 Category: Hematology Authors: I Tirado-Gonzalez E Czlonka A Nevmerzhitskaya D Soetopo E Bergonzani A Mahmoud A Contreras I Jeremias U Platzbecker J P Bourquin U Kloz F Van der Hoeven H Medyouf Source Type: research

Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines
Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines, Published online: 06 December 2017; doi:10.1038/leu.2017.345Biological and prognostic impact of APOBEC-induced mutations in the spectrum of plasma cell dyscrasias and multiple myeloma cell lines (Source: Leukemia)
Source: Leukemia - December 6, 2017 Category: Hematology Authors: F Maura M Petljak M Lionetti I Cifola W Liang E Pinatel L Alexandrov A Fullam I Martincorena K J Dawson N Angelopoulos M K Samur R Szalat J Zamora P Tarpey H Davies P Corradini K Anderson S Minvielle A Neri H Avet-Loiseau J J Keats P J Campbell N Munshi N Source Type: research

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups
Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups, Published online: 06 December 2017; doi:10.1038/leu.2017.344Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups (Source: Leukemia)
Source: Leukemia - December 6, 2017 Category: Hematology Authors: N Bolli G Biancon M Moarii S Gimondi Y Li C de Philippis F Maura V Sathiaseelan Y-T Tai L Mudie S O ’Meara K Raine J W Teague A P Butler C Carniti M Gerstung T Bagratuni E Kastritis M Dimopoulos P Corradini K Anderson P Moreau S Minvielle P J Campbell E Source Type: research

Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: Documentation and cautionary note regarding cell fraction purity
Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: Documentation and cautionary note regarding cell fraction purity, Published online: 05 December 2017; doi:10.1038/leu.2017.343Somatic CLL mutations occur at multiple distinct hematopoietic maturation stages: Documentation and cautionary note regarding cell fraction purity (Source: Leukemia)
Source: Leukemia - December 5, 2017 Category: Hematology Authors: S Marsilio H Khiabanian G Fabbri S Vergani C Scuoppo E Montserrat E J Shpall M Hadigol P Marin K R Rai R Rabadan S Devereux L Pasqualucci N Chiorazzi Source Type: research

MYC-containing amplicons in acute myeloid leukemia: Genomic structures, evolution, and transcriptional consequences
MYC-containing amplicons in acute myeloid leukemia: Genomic structures, evolution, and transcriptional consequences, Published online: 28 November 2017; doi:10.1038/leu.2017.337MYC-containing amplicons in acute myeloid leukemia: Genomic structures, evolution, and transcriptional consequences (Source: Leukemia)
Source: Leukemia - November 28, 2017 Category: Hematology Authors: A ĹAbbate D Tolomeo I Cifola M Severgnini A Turchiano B Augello G Squeo P D ´Addabbo D Traversa G Daniele A Lonoce M Pafundi M Carella O Palumbo A Dolnik D Muehlematter J Schoumans N Van Roy G De Bellis G Martinelli G Merla L Bullinger C Haferlach C T S Source Type: research

MiR-29b antagonizes the pro-inflammatory tumor-promoting activity of multiple myeloma-educated dendritic cells
MiR-29b antagonizes the pro-inflammatory tumor-promoting activity of multiple myeloma-educated dendritic cells, Published online: 21 November 2017; doi:10.1038/leu.2017.336 (Source: Leukemia)
Source: Leukemia - November 21, 2017 Category: Hematology Authors: C Botta M Cuc è M R Pitari D Caracciolo A Gull à E Morelli C Riillo L Biamonte M E G Cantafio R Prabhala C Mignogna A Di Vito E Altomare N Amodio M T Di Martino P Correale M Rossi A Giordano N C Munshi P Tagliaferri P Tassone Source Type: research

Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups
Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups, Published online: 21 November 2017; doi:10.1038/leu.2017.311 (Source: Leukemia)
Source: Leukemia - November 21, 2017 Category: Hematology Authors: A Burns R Alsolami J Becq B Stamatopoulos A Timbs D Bruce P Robbe D Vavoulis R Clifford M Cabes H Dreau J Taylor S J L Knight R Mansson D Bentley R Beekman J I Mart ín-Subero E Campo R S Houlston K E Ridout A Schuh Source Type: research

Protein arginine methyltransferase 5 (PRMT5) has prognostic relevance and is a druggable target in multiple myeloma
Protein arginine methyltransferase 5 (PRMT5) has prognostic relevance and is a druggable target in multiple myeloma, Published online: 21 November 2017; doi:10.1038/leu.2017.334 (Source: Leukemia)
Source: Leukemia - November 21, 2017 Category: Hematology Authors: A Gull à T Hideshima G Bianchi M Fulciniti M K Samur J Qi Y-T Tai T Harada E Morelli N Amodio R Carrasco P Tagliaferri N C Munshi P Tassone K C Anderson Source Type: research

Towards 'off-the-shelf' genetically modified T-Cells: Prolonging functional engraftment in mice by CD8 veto T-cells
Towards 'off-the-shelf' genetically modified T-Cells: Prolonging functional engraftment in mice by CD8 veto T-cells, Published online: 20 November 2017; doi:10.1038/leu.2017.332 (Source: Leukemia)
Source: Leukemia - November 20, 2017 Category: Hematology Authors: N Or-Geva R Gidron-Budovsky L Radomir Y Edelstein A K Singh R Sidlik-Muskatel E Ophir E Bachar-Lustig Y Reisner Source Type: research

Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T cell model system
Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T cell model system, Published online: 20 November 2017; doi:10.1038/leu.2017.328 (Source: Leukemia)
Source: Leukemia - November 20, 2017 Category: Hematology Authors: S Bornschein S Demeyer R Stirparo O Gielen C Vicente E Geerdens B Ghesqui ère S Aerts J Cools C E de Bock Source Type: research

Diagnostic thresholds for free light chains in multiple myeloma depend on the assay used
Diagnostic thresholds for free light chains in multiple myeloma depend on the assay used, Published online: 20 November 2017; doi:10.1038/leu.2017.335 (Source: Leukemia)
Source: Leukemia - November 20, 2017 Category: Hematology Authors: X Bossuyt M Delforge M Reynders D Dillaerts B Sprangers K Fostier K Poesen M Vercammen Source Type: research

Recombinant immunotoxins targeting B-cell maturation antigen are cytotoxic to myeloma cell lines and myeloma cells from patients
Recombinant immunotoxins targeting B-cell maturation antigen are cytotoxic to myeloma cell lines and myeloma cells from patients, Published online: 17 November 2017; doi:10.1038/leu.2017.315 (Source: Leukemia)
Source: Leukemia - November 17, 2017 Category: Hematology Authors: T K Bera Y Abe T Ise A Oberle D Gallardo X-f Liu S Nagata M Binder I Pastan Source Type: research

Management of relapsed & refractory multiple myeloma—novel agents, antibodies, immunotherapies and beyond
Management of relapsed & refractory multiple myeloma—novel agents, antibodies, immunotherapies and beyondManagement of relapsed & refractory multiple myeloma—novel agents, antibodies, immunotherapies and beyond, Published online: 16 November 2017; doi:10.1038/leu.2017.329 (Source: Leukemia)
Source: Leukemia - November 16, 2017 Category: Hematology Authors: C S Chim S Kumar R Orlowski G Cook P G Richardson M Gertz S Giralt M Mateos X Leleu K C Anderson Source Type: research

Early relapse after autologous hematopoietic cell transplantation remains a poor prognostic factor in multiple myeloma but outcomes have improved over time
Early relapse after autologous hematopoietic cell transplantation remains a poor prognostic factor in multiple myeloma but outcomes have improved over time, Published online: 16 November 2017; doi:10.1038/leu.2017.331 (Source: Leukemia)
Source: Leukemia - November 16, 2017 Category: Hematology Authors: S K Kumar A Dispenzieri R Fraser F Mingwei G Akpek R Cornell M Kharfan-Dabaja C Freytes S Hashmi G Hildebrandt L Holmberg R Kyle H Lazarus C Lee J Mikhael T Nishihori J Tay S Usmani D Vesole R Vij B Wirk A Krishnan C Gasparetto T Mark Y Nieto P Hari A D Source Type: research

Phase 1/2 study of weekly carfilzomib, cyclophosphamide, dexamethasone in newly diagnosed transplant-ineligible myeloma
Phase 1/2 study of weekly carfilzomib, cyclophosphamide, dexamethasone in newly diagnosed transplant-ineligible myeloma, Published online: 16 November 2017; doi:10.1038/leu.2017.327 (Source: Leukemia)
Source: Leukemia - November 16, 2017 Category: Hematology Authors: S Bringhen M D ’Agostino L De Paoli V Montefusco A M Liberati P Galieni S Grammatico V E Muccio F Esma C De Angelis P Musto S Ballanti M Offidani R M T Petrucci G Gaidano P Corradini A Palumbo P Sonneveld M Boccadoro Source Type: research

Long-term efficacy and safety of momelotinib, a JAK1 and JAK2 inhibitor, for the treatment of myelofibrosis
Long-term efficacy and safety of momelotinib, a JAK1 and JAK2 inhibitor, for the treatment of myelofibrosis, Published online: 16 November 2017; doi:10.1038/leu.2017.330 (Source: Leukemia)
Source: Leukemia - November 16, 2017 Category: Hematology Authors: A Pardanani J Gotlib A W Roberts M Wadleigh S Sirhan J Kawashima J A Maltzman L Shao V Gupta A Tefferi Source Type: research

Age-related inflammatory bone marrow microenvironment induces ineffective erythropoiesis mimicking del(5q) MDS
Age-related inflammatory bone marrow microenvironment induces ineffective erythropoiesis mimicking del(5q) MDS, Published online: 16 November 2017; doi:10.1038/leu.2017.326 (Source: Leukemia)
Source: Leukemia - November 16, 2017 Category: Hematology Authors: Y Mei B Zhao A A Basiorka J Yang L Cao J Zhang A List P Ji Source Type: research

Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53
Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53, Published online: 16 November 2017; doi:10.1038/leu.2017.325 (Source: Leukemia)
Source: Leukemia - November 16, 2017 Category: Hematology Authors: S Chen R Gao C Yao M Kobayashi S Z Liu M C Yoder H Broxmeyer R Kapur H S Boswell L D Mayo Y Liu Source Type: research

Gene dosage reductions of Trf1 and/or Tin2 induce telomere DNA damage and lymphoma formation in aging mice
Gene dosage reductions of Trf1 and/or Tin2 induce telomere DNA damage and lymphoma formation in aging mice, Published online: 10 November 2017; doi:10.1038/leu.2017.224 (Source: Leukemia)
Source: Leukemia - November 10, 2017 Category: Hematology Authors: K Hartmann A Illing F Leith äuser A Baisantry L Quintanilla-Martinez K L Rudolph Source Type: research

Bruton's Tyrosine Kinase and RAC1 promote cell survival in MLL-rearranged acute myeloid leukemia
Bruton's Tyrosine Kinase and RAC1 promote cell survival in MLL-rearranged acute myeloid leukemia, Published online: 07 November 2017; doi:10.1038/leu.2017.324 (Source: Leukemia)
Source: Leukemia - November 7, 2017 Category: Hematology Authors: S C Nimmagadda S Frey B Edelmann C Hellmich L Zaitseva G M K önig E Kostenis K M Bowles T Fischer Source Type: research

Combination of a novel HDAC 6 inhibitor ACY-241 and anti-PD-L1 antibody enhances anti-tumor immunity and cytotoxicity in multiple myeloma
Combination of a novel HDAC 6 inhibitor ACY-241 and anti-PD-L1 antibody enhances anti-tumor immunity and cytotoxicity in multiple myeloma, Published online: 06 November 2017; doi:10.1038/leu.2017.322 (Source: Leukemia)
Source: Leukemia - November 6, 2017 Category: Hematology Authors: A Ray D S Das Y Song T Hideshima Y-T Tai D Chauhan K C Anderson Source Type: research

Risk of developing chronic myeloid neoplasms in well-differentiated thyroid cancer patients treated with radioactive iodine
Risk of developing chronic myeloid neoplasms in well-differentiated thyroid cancer patients treated with radioactive iodine, Published online: 06 November 2017; doi:10.1038/leu.2017.323 (Source: Leukemia)
Source: Leukemia - November 6, 2017 Category: Hematology Authors: R J Molenaar C Pleyer T Radivoyevitch S Sidana A Godley A S Advani A T Gerds H E Carraway M Kalaycio A Nazha D Adelstein C Nasr D Angelini J P Maciejewski N Majhail M A Sekeres S Mukherjee Source Type: research

Pharmacodynamics and proteomic analysis of acalabrutinib therapy: Similarity of on-target effects to ibrutinib and rationale for combination therapy
Pharmacodynamics and proteomic analysis of acalabrutinib therapy: Similarity of on-target effects to ibrutinib and rationale for combination therapy, Published online: 03 November 2017; doi:10.1038/leu.2017.321 (Source: Leukemia)
Source: Leukemia - November 3, 2017 Category: Hematology Authors: V K Patel B Lamothe M L Ayres J Gay J Cheung K Balakrishnan C Ivan J Morse M Nelson M J Keating W G Wierda J R Marszalek V Gandhi Source Type: research

Prognostic value of antigen expression in multiple myeloma: A PETHEMA/GEM study on 1,265 patients enrolled in four consecutive clinical trials
Prognostic value of antigen expression in multiple myeloma: A PETHEMA/GEM study on 1,265 patients enrolled in four consecutive clinical trials, Published online: 03 November 2017; doi:10.1038/leu.2017.320 (Source: Leukemia)
Source: Leukemia - November 3, 2017 Category: Hematology Authors: P Arana B Paiva M-T Cedena N Puig L Cordon M-B Vidriales N C Gutierrez F Chiodi L Burgos L-L Anglada J Martinez-Lopez M-T Hernandez A-I Teruel M Gironella M-A Echeveste L Rosi ñol R Martinez A Oriol J De la Rubia A Orfao J Blade J-J Lahuerta M-V Mateos J Source Type: research

A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia
A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia, Published online: 03 November 2017; doi:10.1038/leu.2017.319 (Source: Leukemia)
Source: Leukemia - November 3, 2017 Category: Hematology Authors: H Sakai N Hosono H Nakazawa B Przychodzen C Polprasert H E Carraway M A Sekeres T Radivoyevitch K Yoshida M Sanada T Yoshizato K Kataoka M M Nakagawa H Ueno Y Nannya A Kon Y Shiozawa J Takeda Y Shiraishi K Chiba S Miyano J Singh R A Padgett S Ogawa J P Ma Source Type: research

Recombinant immunotoxins targeting B cell maturation antigen are cytotoxic to myeloma cell lines and myeloma cells from patients
Recombinant immunotoxins targeting B cell maturation antigen are cytotoxic to myeloma cell lines and myeloma cells from patients, Published online: 01 November 2017; doi:10.1038/leu.2017.315 (Source: Leukemia)
Source: Leukemia - November 1, 2017 Category: Hematology Authors: T K Bera Y Abe T Ise A Oberle D Gallardo X-f Liu S Nagata M Binder I Pastan Source Type: research

Prognostic significance of ASXL1 mutation types and allele burden in myelofibrosis
Prognostic significance of ASXL1 mutation types and allele burden in myelofibrosis, Published online: 01 November 2017; doi:10.1038/leu.2017.318 (Source: Leukemia)
Source: Leukemia - November 1, 2017 Category: Hematology Authors: A Tefferi T L Lasho C Finke N Gangat C A Hanson R P Ketterling A Pardanani Source Type: research

Targeting acute myeloid leukemia by drug-induced c-MYB degradation
Targeting acute myeloid leukemia by drug-induced c-MYB degradation, Published online: 01 November 2017; doi:10.1038/leu.2017.317 (Source: Leukemia)
Source: Leukemia - November 1, 2017 Category: Hematology Authors: V Walf-Vorderw ülbecke K Pearce T Brooks M Hubank M M van den Heuvel-Eibrink C M Zwaan S Adams D Edwards J Bartram S Samarasinghe P Ancliff A Khwaja N Goulden G Williams J de Boer O Williams Source Type: research

Identification and characterization of HLA-A24 specific XBP1, CD138 (Syndecan-1), and CS1 (SLAMF7) peptides inducing antigens-specific memory cytotoxic T lymphocytes targeting multiple myeloma
Identification and characterization of HLA-A24 specific XBP1, CD138 (Syndecan-1), and CS1 (SLAMF7) peptides inducing antigens-specific memory cytotoxic T lymphocytes targeting multiple myeloma, Published online: 01 November 2017; doi:10.1038/leu.2017.316 (Source: Leukemia)
Source: Leukemia - November 1, 2017 Category: Hematology Authors: J Bae T Hideshima G L Zhang J Zhou D B Keskin N C Munshi K C Anderson Source Type: research

Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia
Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia, Published online: 01 November 2017; doi:10.1038/leu.2017.313 (Source: Leukemia)
Source: Leukemia - November 1, 2017 Category: Hematology Authors: L Lhermitte E Mejstrikova A J van der Sluijs-Gelling G E Grigore L Sedek A E Bras G Gaipa E S da Costa M Novakova E Sonneveld C Buracchi T de S á Bacelar J G te Marvelde A Trinquand V Asnafi T Szczepanski S Matarraz A Lopez B Vidriales J Bulsa O Hrusak T Source Type: research

The role of bone marrow morphology in the diagnosis of relapsed acute myeloid leukemia
Leukemia, Published online: 31 October 2017; doi:10.1038/leu.2017.308 (Source: Leukemia)
Source: Leukemia - October 31, 2017 Category: Hematology Authors: B Said S Gilles D Weisdorf A Rashidi Source Type: research

Targetable fusions of the FRK tyrosine kinase in ALK-negative anaplastic large cell lymphoma
Leukemia, Published online: 13 October 2017; doi:10.1038/leu.2017.309 (Source: Leukemia)
Source: Leukemia - October 13, 2017 Category: Hematology Authors: G Hu S Dasari Y W Asmann P T Greipp R A Knudson H K Benson Y Li B W Eckloff Jin Jen B K Link L Jiang J S Sidhu L E Wellik T E Witzig N N Bennani J R Cerhan R L Boddicker A L Feldman Source Type: research

A vicious loop of fatty acid-binding protein 4 and DNA methyltransferase 1 promotes acute myeloid leukemia and acts as a therapeutic target
Leukemia, Published online: 10 October 2017; doi:10.1038/leu.2017.307 (Source: Leukemia)
Source: Leukemia - October 10, 2017 Category: Hematology Authors: F Yan N Shen J X Pang N Zhao Y W Zhang A M Bode A Al-Kali M R Litzow B Li S J Liu Source Type: research

Blinatumomab retreatment after relapse in patients with relapsed/refractory B-precursor acute lymphoblastic leukemia
Leukemia, Published online: 9 October 2017; doi:10.1038/leu.2017.306 (Source: Leukemia)
Source: Leukemia - October 9, 2017 Category: Hematology Authors: M S Topp M Stelljes G Zugmaier P Barnette L T Heffner T Trippett J Duell R C Bargou C Holland J E Benjamin M Klinger M R Litzow Source Type: research

RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia
Leukemia, Published online: 3 October 2017; doi:10.1038/leu.2017.303 (Source: Leukemia)
Source: Leukemia - October 3, 2017 Category: Hematology Authors: I S Jerchel A Q Hoogkamer I M Ari ës E M P Steeghs J M Boer N J M Besselink A Boeree C van de Ven H A de Groot-Kruseman V de Haas M A Horstmann G Escherich C M Zwaan E Cuppen M J Koudijs R Pieters M L den Boer Source Type: research

Lenalidomide-mediated erythroid improvement in non-del(5q) myelodysplastic syndromes is associated with bone marrow immuno-remodeling
Leukemia, Published online: 3 October 2017; doi:10.1038/leu.2017.305 (Source: Leukemia)
Source: Leukemia - October 3, 2017 Category: Hematology Authors: G Kerdivel V Chesnais E Becht A Toma N Cagnard F Dumont A Rousseau P Fenaux S Chevret N Chapuis V Boeva W H Fridman M Fontenay O Kosmider Source Type: research

Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B cell function and inhibition of the PD-1/PD-L1 pathway
Leukemia, Published online: 3 October 2017; doi:10.1038/leu.2017.304 (Source: Leukemia)
Source: Leukemia - October 3, 2017 Category: Hematology Authors: K Kondo H Shaim P A Thompson J A Burger M Keating Z Estrov D Harris E Kim A Ferrajoli M Daher R Basar M Muftuoglu N Imahashi A Alsuliman C Sobieski E Gokdemir W Wierda N Jain E Liu E J Shpall K Rezvani Source Type: research

RAS pathway mutations as predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia
Leukemia, Published online: 3 October 2017; doi:10.1038/leu.2017.303 (Source: Leukemia)
Source: Leukemia - October 3, 2017 Category: Hematology Authors: I S Jerchel A Q Hoogkamer I M Ari ës E M P Steeghs J M Boer N J M Besselink A Boeree C van de Ven H A de Groot-Kruseman V de Haas M A Horstmann G Escherich C M Zwaan E Cuppen M J Koudijs R Pieters M L den Boer Source Type: research

JAM-A as a prognostic factor and new therapeutic target in multiple myeloma
Leukemia, Published online: 28 September 2017; doi:10.1038/leu.2017.287 (Source: Leukemia)
Source: Leukemia - September 28, 2017 Category: Hematology Authors: A G Solimando A Brandl K Mattenheimer C Graf M Ritz A Ruckdeschel T St ühmer Z Mokhtari M Rudelius J Dotterweich M Bittrich V Desantis R Ebert P Trerotoli M A Frassanito A Rosenwald A Vacca H Einsele F Jakob A Beilhack Source Type: research

Dual inhibition of EZH1/2 breaks the quiescence of leukemia stem cells in acute myeloid leukemia
Leukemia, Published online: 27 September 2017; doi:10.1038/leu.2017.300 (Source: Leukemia)
Source: Leukemia - September 27, 2017 Category: Hematology Authors: S Fujita D Honma N Adachi K Araki Ei Takamatsu T Katsumoto K Yamagata K Akashi K Aoyama A Iwama I Kitabayashi Source Type: research

A compound chimeric antigen receptor strategy for targeting multiple myeloma
Leukemia, Published online: 27 September 2017; doi:10.1038/leu.2017.302 (Source: Leukemia)
Source: Leukemia - September 27, 2017 Category: Hematology Authors: K H Chen M Wada K G Pinz H Liu X Shuai X Chen L E Yan J C Petrov H Salman L Senzel E L H Leung X Jiang Y Ma Source Type: research

Therapeutic targeting of CK2 in acute and chronic leukemias
Leukemia, Published online: 27 September 2017; doi:10.1038/leu.2017.301 (Source: Leukemia)
Source: Leukemia - September 27, 2017 Category: Hematology Authors: F Buontempo J A McCubrey E Orsini M Ruzzene A Cappellini A Lonetti C Evangelisti F Chiarini C Evangelisti J T Barata A M Martelli Source Type: research

NG2 antigen is involved in leukemia invasiveness and central nervous system infiltration in MLL-rearranged infant B-ALL
Leukemia, Published online: 25 September 2017; doi:10.1038/leu.2017.294 (Source: Leukemia)
Source: Leukemia - September 25, 2017 Category: Hematology Authors: C Prieto B L ópez-Millán H Roca-Ho R W Stam D Romero-Moya F J Rodr íguez-Baena A Sanjuan-Pla V Ayll ón M Ram írez M Bardini P De Lorenzo M G Valsecchi M Stanulla M Iglesias P Ballerini ÁM Carcaboso J Mora F Locatelli A Bertaina L Padilla J C Rodr í Source Type: research

Johannes Joseph van Rood Pioneer in immuno-genetics (7 April 1926–21 July 2017)
Johannes Joseph van Rood Pioneer in immuno-genetics (7 April 1926–21 July 2017)Leukemia, Published online: 1 October 2017; doi:10.1038/leu.2017.278 (Source: Leukemia)
Source: Leukemia - September 22, 2017 Category: Hematology Authors: W Fibbe R P Gale Source Type: research

Johannes Joseph van Rood Pioneer in immuno-genetics (7 April 1926 – 21 July 2017)
Johannes Joseph van Rood Pioneer in immuno-genetics (7 April 1926–21 July 2017) Leukemia advance online publication, September 22 2017. doi:10.1038/leu.2017.278 Authors: W Fibbe & R P Gale (Source: Leukemia)
Source: Leukemia - September 22, 2017 Category: Hematology Authors: W Fibbe R P Gale Source Type: research