Educational strategy intervention and remote supervision on the post ‐discharge management of tuberculosis diagnosed in the hospital: randomized clinical trial
ConclusionAn educational strategy intervention and remote supervision on the post ‐discharge management of new cases of TB with in‐hospital diagnosis had a positive effect of small magnitude on cure rate. Secondarily, the treatment default rate has been significantly decreased with the intervention.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 17, 2019 Category: Respiratory Medicine Authors: Alice M ânica Müller, Cecília Susin Osório, Raíssa Velasquez Figueiredo, Denise Rossato Silva, Paulo de Tarso Roth Dalcin Tags: Original Article Source Type: research

Association between features of COPD and risk of venous thromboembolism
Conclusionsvisual emphysema is an independent risk factor for VTE events and the risk of VTE in COPD patients increases with the degree of airway obstruction. However, there is no evidence of an association between exacerbation frequency and VTE events.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 7, 2019 Category: Respiratory Medicine Authors: Weigang Dong, Yaqian Zhu, Yan Du, Shuping Ma Tags: Original Article Source Type: research

Issue Information
The Clinical Respiratory Journal, Volume 13, Issue 6, Page 339-340, June 2019. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - June 3, 2019 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Survival after ward ‐based non‐invasive ventilation for chronic obstructive pulmonary disease exacerbations: Ceiling treatment or causality?
The Clinical Respiratory Journal, EarlyView. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 20, 2019 Category: Respiratory Medicine Authors: Maria Alvarenga Santos, Antonio M. Esquinas Tags: LETTER TO THE EDITOR Source Type: research

Serum prealbumin is a prognostic indicator in idiopathic pulmonary fibrosis
AbstractIntroductionIdiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease characterized by variable progression. The prealbumin (PA) is a parameter in a routine blood biochemistry examination. We sought to investigate the prognostic value in IPF patients.ObjectivesTo evaluate the prognosis value in patients with IPF.MethodsBlood biochemistry examination, demographics, pulmonary function data from patients with IPF consulted in Beijing Chao ‐Yang Hospital and China‐Japan Friendship Hospital between July 2012 and December 2016 were collected. Infection, liver and kidney dysfunction and lung transplanta...
Source: The Clinical Respiratory Journal - May 18, 2019 Category: Respiratory Medicine Authors: Biyun Li, Xinran Zhang, Guodong Xu, Shu Zhang, Huifang Song, Kaiyuan Yang, Huaping Dai, Chen Wang Tags: Original Article Source Type: research

Clinical characteristics of pulmonary hypertension patients living in plain and high ‐altitude regions
AbstractObjectiveThe demographic characteristics, ratio of aetiologies, and biochemical parameters of adult patients with pulmonary hypertension (PH) living in plain and high ‐altitude regions were investigated and analysed.MethodsIn total, 2,846 adult patients with PH hospitalized from 2010 to 2015 in the Second Xiangya Hospital of Central South University and Qinghai Red Cross Hospital were retrospectively investigated.Results(1) In the present study, the numbers of patients with PH in both the plain and high ‐altitude regions increased annually (P
Source: The Clinical Respiratory Journal - May 16, 2019 Category: Respiratory Medicine Authors: Si Lei, Zhina Sun, Xiuqin He, Cheng Li, Yiqing Zhang, Xihong Luo, Shangjie Wu Tags: Original Article Source Type: research

Aspergillosis Related to Severe Influenza: A Worldwide Phenomenon?
This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 10, 2019 Category: Respiratory Medicine Authors: Wei ‐Lun Liu, Wen‐Liang Yu, Khee‐Siang Chan, Chun‐Chieh Yang, Joost Wauters, Paul E Verweij Tags: LETTER TO THE EDITOR Source Type: research

Corrigendum
The Clinical Respiratory Journal, Volume 13, Issue 5, Page 338-338, May 2019. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 8, 2019 Category: Respiratory Medicine Tags: CORRIGENDUM Source Type: research

Issue Information
The Clinical Respiratory Journal, Volume 13, Issue 5, Page 267-268, May 2019. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 8, 2019 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Thematic series: Novel insights in pleural diseases
The Clinical Respiratory Journal, Volume 13, Issue 5, Page 269-271, May 2019. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 8, 2019 Category: Respiratory Medicine Authors: Marios E. Froudarakis Tags: EDITORIAL Source Type: research

Survival after ward ‐based noninvasive ventilation for chronic obstructive pulmonary disease exacerbations: ceiling treatment or causality?
This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 7, 2019 Category: Respiratory Medicine Authors: Maria Alvarenga Santos, Antonio M. Esquinas Tags: Letter to the Editor Source Type: research

A meta ‐analysis of randomized controlled trials in targeted treatments of chronic thromboembolic pulmonary hypertension
ConclusionsThis is the first systematic review and meta ‐analysis of randomized controlled trials revealing a positive role of PAH‐targeted therapies in CTEPH. Future larger randomized trials with a focus on long‐term clinical outcomes are urgently needed.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 6, 2019 Category: Respiratory Medicine Authors: Jing Zhang, Jing ‐Meng Li, Zan‐Sheng Huang, Jian‐Cheng Xu, Ye Fan Tags: Original Article Source Type: research

Abolishing the venous –arterial CO2 gradient as treatment for singultus: Commentary on Obuchi et al. (2018)
The Clinical Respiratory Journal, EarlyView. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 5, 2019 Category: Respiratory Medicine Authors: Georg A. Petroianu Tags: LETTER TO THE EDITOR Source Type: research

Exercise capacity in borderline mean pulmonary artery pressure: Is it all about peak VO2?
This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - May 3, 2019 Category: Respiratory Medicine Authors: Afroditi K. Boutou, Georgia Pitsiou, Evangelia Panagiotidou, Ioannis Stanopoulos Tags: Letter to the Editor Source Type: research

Clinical features and prognosis of microscopic polyangiitis with usual interstitial pneumonia compared with idiopathic pulmonary fibrosis
ConclusionUIP is the most frequent type of MPA ‐IP. These patients tend to have longer duration of symptoms prior to diagnosis and usually have pulmonary involvement as the first presentation. However, they are less likely to have proteinuria and/or hematuria. MPA patients with UIP can be differentiated from IPF patients through comprehensive analysis of clinical and laboratory findings.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 23, 2019 Category: Respiratory Medicine Authors: Wen Zhao, Huaping Dai, Yan Liu, Min Zhu, Na Bao, Chengjun Ban, Shu Zhang, Yanhong Ren, Qiao Ye, Chen Wang Tags: Original Article Source Type: research

The v ‐DECAF score can predict 90‐day all‐cause mortality in patients with COPD exacerbation requiring invasive mechanical ventilation
This study prospectively recruited 112 consecutive AECOPD patients requiring IMV from a single center. The clinical endpoint was 90 ‐day all‐cause mortality. Demographic and clinical data were recorded, as well as APACHE II, GCS, CURB‐65, BAP‐65 and DECAF scores, and the newly devised v‐DECAF score. The discriminatory value of the scoring systems in predicting 90‐day all‐cause mortality was determined using the are a under the receiver operating characteristic (AUROC) curve.ResultsIn multivariate logistic regression analysis, the v ‐DECAF score was an independent predictor of 90‐day all‐cause mortality ...
Source: The Clinical Respiratory Journal - April 22, 2019 Category: Respiratory Medicine Authors: Qi ‐fang Shi, Ying Sheng, Nian Zhu, Yan Tan, Xiao‐Hong Xie, Shu‐yun Wang, Jin‐fang Cai Tags: ORIGINAL ARTICLE Source Type: research

Changes in ventilation and perfusion following lower lobe Endoscopic Lung Volume Reduction (ELVR) with endobronchial valves in COPD: A Preliminary Report
AbstractBackgroundWe have previously reported significant improvements in ventilation and perfusion (VQ) and V/Q matching in the contralateral lung, especially the non targeted lower zone in patients with severe COPD following upper lobe ELVR with endobronchial valves. However, V/Q changes after lower lobe ELVR have not been described.Methods7 patients with lower lobe heterogeneous emphysema underwent unilateral lower lobe ELVR at Macquarie University Hospital. Lung function tests, 6 ‐minute walk tests (6MWT), St George's Respiratory Questionnaire (SGRQ), and planar differential VQ scans were performed at baseline and at...
Source: The Clinical Respiratory Journal - April 21, 2019 Category: Respiratory Medicine Authors: Li Yang, Kelvin Hsu, Jonathan P. Williamson, Matthew J. Peters, Kevin Ho ‐Shon, Alvin J. Ing Tags: Original Article Source Type: research

Adverse effect of smoking on cross ‐sectional area of small pulmonary vessel and arterial stiffness in healthy smokers without COPD
This study aimed to explore association between the CSA of small pulmonary vessel and arterial stiffness in healthy male smokers.MethodsWe enrolled 90 male non ‐smokers and 90 male smokers (age: 51.5 ± 9.7 years and 52.1 ± 7.9 years, respectively). All subjects underwent chest computed tomography (CT), pulmonary function test and baPWV measurement. We evaluated the total CSAs less than 5 mm2 using ImageJ software and divided by the total lung area (%CSA
Source: The Clinical Respiratory Journal - April 10, 2019 Category: Respiratory Medicine Authors: Hwang Hee Jo, Mi Jung Park, Hwa Seon Shin, Hye Young Choi, Jae Boem Na, Dae Seob Choi, Ho Cheol Choi, Sang Min Lee, Gyeong ‐Won Lee, Seung Jun Lee Tags: ORIGINAL ARTICLE Source Type: research

Effects of Exercise ‐induced Dyspnoea on the Aspiration Rate among Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
ConclusionRecovering AECOPD patients had significantly higher silent aspiration rates than healthy volunteers of similar age. The evidence is not strong enough to support the patients with exercise ‐induced dyspnoea increased aspiration rate.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 9, 2019 Category: Respiratory Medicine Authors: Ni Liu, Youxia Li, Ping Chen, Zhida Wu, Peng Hou, Zeguang Zheng, Rongchang Chen Tags: Original Article Source Type: research

The v ‐DECAF score can predict 90 day all‐cause mortality in patients with COPD exacerbation requiring invasive mechanical ventilation
The objective of this study was to compare the predictive efficacy of the v‐DECAF score and the DECAF score.MethodsThis  study prospectively recruited 112 consecutive AECOPD patients requiring IMV from a single center. The clinical endpoint was 90 day all‐cause mortality. Demographic and clinical data were recorded, as well as APACHE II, GCS, CURB‐65, BAP‐65, and DECAF scores, and the newly devised v‐DECA F score. The discriminatory value of the scoring systems in predicting 90 day all‐cause mortality was determined using the area under the receiver operating characteristic (AUROC) curve.Res...
Source: The Clinical Respiratory Journal - April 6, 2019 Category: Respiratory Medicine Authors: Qi ‐fang Shi, Ying sheng, Nian Zhu, Yan Tan, Xiao‐Hong Xie, Shu‐yun Wang, Jin‐fang Cai Tags: Original Article Source Type: research

Thematic Series: Novel Insights In Pleural Diseases Editorial: Pleural Disease: a continuously improved information
This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 6, 2019 Category: Respiratory Medicine Authors: Marios E. Froudarakis Tags: Editorial Source Type: research

Do the Global Lung Function Initiative reference equations reflect a sample of adult Middle Eastern population ?
Conclusion: A need to formulate a specific equation for the Jordanian population is urgently required to better evaluate their respiratory conditions.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 5, 2019 Category: Respiratory Medicine Authors: Walid A. Al ‐Qerem, Alaa M. Hammad, Rania A. AlQirem, Jonathan Ling Tags: Original Article Source Type: research

Triple versus Dual Inhaler therapy in moderate ‐to‐severe COPD: A systematic review and meta‐analysis of randomized controlled trials
AbstractIntroductionTreatment of COPD is evolving specially with triple inhaler therapy.ObjectivesTo perform a meta ‐analysis to ascertain the safety and efficacy of triple inhaler therapy consisting of an inhaled‐glucocorticoid (ICS), long‐acting muscarinic‐antagonist (LAMA), and long‐acting β2‐agonist (LABA) when compared with dual therapy (ICS‐LABA or LAMA‐LABA).MethodsWe performed an electronic database search to include randomized controlled trials (RCTs) comparing between triple and dual inhalers. Pooled rate ‐ratio (RR) or odds‐ratio (OR) for dichotomous data and weighted mean difference (MD...
Source: The Clinical Respiratory Journal - April 4, 2019 Category: Respiratory Medicine Authors: Yazan Zayed, Mahmoud Barbarawi, Babikir Kheiri, Tarek Haykal, Adam Chahine, Laith Rashdan, Kewan Hamid, Saira Sundus, Momen Banifadel, Ahmed Aburahma, Ghassan Bachuwa, Arul Chandran Tags: Review Article Source Type: research

Comparison of the prognostic capability of two comorbidity indices in patients with chronic obstructive pulmonary disease, in real ‐life clinical practice
ConclusionWhen used in real ‐life clinical practice, the value of the CCI to predict all‐cause mortality in COPD seems higher than that of the COTE index.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 4, 2019 Category: Respiratory Medicine Authors: Juan Marco Figueira ‐Gonçalves, Rafael Golpe, Miguel Ángel García‐Bello, Ignacio García‐Talavera, Olalla Castro‐Añón Tags: Brief Report Source Type: research

Noninvasive ventilation and renal replacement therapy in Do ‐not‐Intubate Order critically ill patients: a brief report
ConclusionOur data suggest that RRT could be feasible together with NIV. RRT was associated with an acute improvement in renal function but did not modify the mortality rate. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 3, 2019 Category: Respiratory Medicine Authors: Vito Catalanotti, Lara Pisani, Sara Betti, Serena Bensai, Irene Prediletto, Luca Fasano, Stefano Nava Tags: Brief Report Source Type: research

Carotid intima ‐media thickness in chronic obstructive pulmonary disease and survival: A Multicenter Prospective Study
AbstractIntroductionChronic obstructive pulmonary disease (COPD) is associated with increased cardiovascular morbidity and mortality. Carotid intima ‐media thickness (CIMT) is a non‐invasive method assessing atherosclerosis.ObjectiveIt was aimed to determine relationship and survival between COPD and CIMT.MethodsCIMT was measured using Doppler ultrasound(USG) in 668 stable COPD patients at 24 centers. Patients were followed ‐up for two years.ResultsThere were 610 patients who completed the study. There were 200 patients CIMT with
Source: The Clinical Respiratory Journal - April 3, 2019 Category: Respiratory Medicine Authors: G Gulbas, O Turan, N Sarioglu, O ErcenDiken, N Ogan, E EkbicKadioglu, E Kurtipek, F Bozkus, N DemirciYilmaz, A CoskunBeyan, L C Mutlu, S S Duyar, S Deniz, N Fazlioglu, A Sengul, H Tanriverdi, O Okutan, A Turan, H İnonu, G Ortakoylu, H Tags: Original Article Source Type: research

OSA treatment with CPAP: Randomized crossover study comparing tolerance and efficacy with and without humidification by ThermoSmart ™
ConclusionThermoSmart™ helps to decrease nose and throat discomfort due to CPAP therapy, these effects did not translate to better compliance but patients had a preference for ThermoSmart™.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 2, 2019 Category: Respiratory Medicine Authors: Laurent Boyer, Carole Philippe, Ala Covali ‐Noroc, Marie‐Amélie Dalloz, Anny Rouvel‐Tallec, Dominique Maillard, Maria Stoica, Marie‐Pia d'OrthoMD Tags: Original Article Source Type: research

Issue Information
The Clinical Respiratory Journal, Volume 13, Issue 4, Page 193-194, April 2019. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - April 1, 2019 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Impaired glucose tolerance, body mass index and respiratory function in patients with cystic fibrosis: A systematic review
ConclusionAlthough this review does not prove cause and effect, BMI and FEV1 are important outcome measures in patients with CF. Considering the inconclusive findings, practitioners should individualize care for this patient population. Additional research should focus on clinical status and interventions/treatment for individuals with CF and IGT.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 28, 2019 Category: Respiratory Medicine Authors: Courtney Iwanicki, John V. Logomarsino Tags: Review Article Source Type: research

Adverse effect of cigarette smoking on cross sectional area of small pulmonary vessel and arterial stiffness in healthy smokers without COPD
This study aimed to explore association between the CSA of small pulmonary vessel and arterial stiffness in healthy male smokers.MethodsWe enrolled 90 male non ‐smokers and 90 male smokers (age: 51.5±9.7 years and 52.1±7.9 years, respectively). All subjects underwent chest computed tomography (CT), pulmonary function test and baPWV measurement. We evaluted the total CSAs less than 5 mm2 using ImageJ software and divided by the total lung area (%CSA
Source: The Clinical Respiratory Journal - March 27, 2019 Category: Respiratory Medicine Authors: Hwang Hee Jo, Mi Jung Park, Hwa Seon Shin, Hye Young Choi, Jae Boem Na, Dae Seob Choi, Ho Cheol Choi, Sang Min Lee, Gyeong ‐Won Lee, Seung Jun Lee Tags: Original Article Source Type: research

Single versus bilateral lung transplantation for idiopathic pulmonary fibrosis
This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 27, 2019 Category: Respiratory Medicine Authors: Dong Wei, Fei Gao, Bo Wu, Min Zhou, Ji Zhang, Hang Yang, Dong Liu, Li Fan, Jingyu Chen Tags: Original Article Source Type: research

Abolishing the venous ‐arterial CO2 gradient as treatment for singultus: Commentary on Obuchi et al, 2018
This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 26, 2019 Category: Respiratory Medicine Authors: Georg A Petroianu Tags: Letter to the Editor Source Type: research

Comparing the effects and compliance between volume ‐assured and pressure support non‐invasive ventilation in patients with chronic respiratory failure
ConclusionsThe evidence shows there is no significant difference in clinical outcomes when comparing AVAPS and PS ‐NIV used for chronic respiratory failure patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 25, 2019 Category: Respiratory Medicine Authors: Xu An Huang, Yan Ping Du, Liu Xia Li, Fang Fang Wu, Shao Qing Hong, Fang Xuan Tang, Zhang Qiang Ye Tags: ORIGINAL ARTICLE Source Type: research

Screening instrument to identify skin prick test ‐negative patients with asthma and/or rhinitis
ConclusionsWe designed a highly specific 13 ‐item instrument for identifying SPT‐negative patients. It may be used in middle income countries where allergy testing is expensive, not reimbursed or few allergy clinics are available. We think that our idea is interesting, that needs further research. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 24, 2019 Category: Respiratory Medicine Authors: Ebru Celebioglu, Ahmet Ugur Demir, Gul Karakaya, Ali Fuat Kalyoncu Tags: ORIGINAL ARTICLE Source Type: research

Factors contributing to COPD hospitalisations from 2010 to 2015: Variation among rural and metropolitan Australians
ConclusionThis investigation highlights many rural and regional areas have much lower COPD hospitalisation rates than metropolitan areas. Between males and females, there are heterogenetic factors that contribute to the significant variation associated with COPD hospitalisation in metropolitan and rural areas, such as rural land use among rural males. This indicates that risk factor assessments, beyond smoking alone, need to be individualised and prioritised in practice to optimise care. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 18, 2019 Category: Respiratory Medicine Authors: Daniel R. Terry, Hoang Nguyen, Jeong ‐Ah Kim, Md Rafiqul Islam Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
The Clinical Respiratory Journal, Volume 13, Issue 3, Page 129-130, March 2019. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 6, 2019 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Novel insights into the systemic treatment of lung cancer malignant pleural effusion
AbstractLung cancer is the most common fatal malignancy worldwide. Approximately 75% of non ‐small‐cell lung cancer (NSCLC) patients are diagnosed at an advanced or a metastatic stage. Since 2007, NSCLC patients with malignant pleural effusion (MPE) are staged as M1 disease. During the last decades, chemotherapeutic agents failed to offer a significant improvement of survival in patien ts with metastatic disease. The current review aims to summarize the actual situation of the recently developed therapies in patients with lung cancer and MPE. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 6, 2019 Category: Respiratory Medicine Authors: Claire Tissot, Pierre Gay, Cl ément Brun, Marios E. Froudarakis Tags: SERIES ON PLEURAL DISEASES Source Type: research

Diagnosis and management of asthma, COPD and asthma ‐COPD overlap among primary care physicians and respiratory/allergy specialists: a global survey
ConclusionWhile most PCPs and respiratory/allergy specialists can reach a working diagnosis of ACO, there remains uncertainty around which diagnostic features are most important and what constitutes optimal management. It is imperative that clinical studies including patients with ACO are initiated, allowing the generation of evidence ‐based management strategies.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 2, 2019 Category: Respiratory Medicine Authors: Christine Jenkins, J. Mark FitzGerald, Fernando J. Martinez, Dirkje S. Postma, Stephen Rennard, Thys van der Molen, Asparuh Gardev, Eduardo Genofre, Peter Calverley Tags: Original Article Source Type: research

Repetitive saliva swallowing test and water swallowing test may identify a COPD phenotype at high risk of exacerbation
AbstractIntroductionPatients with chronic obstructive pulmonary disease (COPD) are known to present with dysphagia from an early stage. Dysphagia leads to swallowing ‐related complications, in turn leading to COPD exacerbation. Dysphagia screening is recommended; however little is known of its utility in detecting a COPD phenotype at risk for exacerbation. The simple swallowing provocation test (SSPT), considered to be a standard screening test, requires speci fic equipment, physician skill, and patient discomfort.ObjectivesThe aim of this study was to find an easier and less invasive measure to screen for dysphagia in p...
Source: The Clinical Respiratory Journal - March 1, 2019 Category: Respiratory Medicine Authors: Yuki Yoshimatsu, Kazunori Tobino, Takuto Sueyasu, Saori Nishizawa, Yuki Goto, Kojin Murakami, Miyuki Munechika, Kohei Yoshimine, Hiroyuki Miyajima Tags: Original Article Source Type: research

Clinical and radiological manifestations of lipoid pneumonia according to etiology: squalene, omega ‐3‐acid ethyl esters, and idiopathic
ConclusionsIn comparison with the exogenous group, the idiopathic group demonstrated BAL lymphocytosis, higher rates of recurrence and BAF, and a higher rate of crazy ‐paving pattern. Compared with the O‐3‐AEE group, the squlaene group showed a higher percentage of BAL neutrophils and predominant RML involvement.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - March 1, 2019 Category: Respiratory Medicine Authors: Seung ‐Ick Cha, Sun Ha Choi, Hyun Jung Kim, Yeon Jae Kim, Jae‐Kwang Lim, Seung‐Soo Yoo, Shin‐Yup Lee, Jaehee Lee, Chang‐Ho Kim, Jae‐Yong Park Tags: Original Article Source Type: research

Factors contributing to COPD hospitalisations from 2010 –2015: Variation among rural and metropolitan Australians
ConclusionThis investigation highlights many rural and regional areas have much lower COPD hospitalisation rates than metropolitan areas. Between males and females, there are heterogenetic factors that contribute to the significant variation associated with COPD hospitalisation in metropolitan and rural areas, such as rural land use among rural males. This indicates that risk factor assessments, beyond smoking alone, need to be individualised and prioritised in practice to optimise care.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 28, 2019 Category: Respiratory Medicine Authors: Daniel Terry, Hoang Nguyen, Jeong ‐Ah Kim, Md Rafiqul Islam Tags: Original Article Source Type: research

Screening instrument to identify skin prick test negative patients with asthma and/or rhinitis
ConclusionsWe designed a highly specific 13 ‐item instrument for identifying SPT‐negative patients. It may be used in middle income countries where allergy testing is expensive, not reimbursed or few allergy clinics are available. We think that our idea is interesting, that needs further research.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 27, 2019 Category: Respiratory Medicine Authors: Ebru Celebioglu, Ahmet Ugur Demir, Gul Karakaya, Ali Fuat Kalyoncu Tags: Original Article Source Type: research

The impact of therapy on the risk of asthma in type 2 diabetes
ConclusionsT2DM may have a protective effect against asthma development. Insulin use was associated with an increased risk of asthma, whilst metformin and sulphonylureas reduced the risk in those with T2DM.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 27, 2019 Category: Respiratory Medicine Authors: Louise H. Rayner, Andrew P Mcgovern, Julian Sherlock, Piers Gatenby, Ana Correa, Ben Creagh ‐Brown, Simon De Lusignan Tags: Original Article Source Type: research

Intrapleural Immunotherapy: An Update on Emerging Treatment Strategies for Pleural Malignancy
ConclusionIntrapleural immunotherapies for pleural malignancy have demonstrated promise with regards to generating durable tumor ‐specific immune responses with possible clinical benefits which merit further investigation as part of multimodal chemo‐ and immunotherapeutic regimens.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 27, 2019 Category: Respiratory Medicine Authors: Vivek Murthy, Daniel Katzman, Daniel H. Sterman Tags: Series on Pleural Diseases Source Type: research

Comparing the Effects and Compliance between Volume Assured and Pressure Support Non ‐invasive Ventilation in Patients with Chronic Respiratory Failure
ConclusionsThe evidence shows there is no significant difference in clinical outcomes when comparing AVAPS and PS ‐NIV used for Chronic Respiratory Failure patients (CRF).This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 25, 2019 Category: Respiratory Medicine Authors: Xu An Huang, Yan Ping Du, Liu ‐Xia Li, Fang Fang Wu, Shao Qing Hong, Fang Xuan Tang, Zhang Qiang Ye Tags: Original Article Source Type: research

The effect of atrial fibrillation intervention on nocturnal respiratory events in elderly patients with persistent AF
ConclusionsSDB is highly prevalent in patients with persistent AF. Restoration of sinus rhythm, and the associated long ‐term recovery of haemodynamics, is associated with a significant reduction in AHI. This implicates reversal of fluid shift from the lower limbs to the neck region, a key mechanism in the pathogenesis of SDB.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 21, 2019 Category: Respiratory Medicine Authors: W Eysenck, N Sulke, N Freemantle, N R Patel, S S Furniss, R A Veasey Tags: Original Article Source Type: research

Issue Information
The Clinical Respiratory Journal, Volume 13, Issue 2, Page 71-72, February 2019. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 21, 2019 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Most Impactful Predictors for Hyperoxaemia in Exacerbation of Chronic Obstructive Pulmonary Disease Managed by Emergency Medical Services And Emergency Department
We reported adjusted odds ratios (AORs), 95% CIs and p values. We selected output factors using AOR ≥ 2.0 and ≥ 2.5 for modifiable and non‐ modifiable factors respectively. These selected factors were fed into a final model with eventual factors selected based on: threshold AORs as stated above and/or 95% CIs including these AORs.Results326 patients were analysed; 60.7% had hyperoxemia. We found three eventual modifiable factors; first ED SpO2> 95% [AOR 2.62 (95% CIs: 1.61 – 4.33); p
Source: The Clinical Respiratory Journal - February 19, 2019 Category: Respiratory Medicine Authors: Beng Leong Lim, Si Oon Cheah, Hsin Kai Goh, Francis Chun Yue Lee, Yih Yng Ng, Wen Jia Guo, Marcus Eng Hock Ong Tags: Original Article Source Type: research

Higher serum levels of systemic inflammatory markers are linked to greater inspiratory muscle dysfunction in copd
AbstractBackgroundCOPD is associated with an inflammatory response that becomes more pronounced in acute exacerbations. Considerable attention has recently focused on the value of several inflammatory mediators in predicting worsening of COPD ‐related symptoms. Whereas respiratory muscle dysfunction is also widely present in this population, little is known about how systemic inflammation relates to inspiratory muscle dysfunction in COPD.Methods53 males with mild ‐to‐very severe airflow obstruction underwent blood sampling for 23 inflammatory markers including acute‐phase proteins, cytokines, and adipokines. Inspir...
Source: The Clinical Respiratory Journal - February 18, 2019 Category: Respiratory Medicine Authors: Magno F. Formiga, Isabel Vital, Gisel Urdaneta, Brett Masters, Julio Herrera, Michael A. Campos, Lawrence P. Cahalin Tags: Original Article Source Type: research

Performance of new spirometry reference values in preoperative assessment of lung function
ConclusionAllegedly lung ‐healthy current smokers showed a higher proportion of preoperatively reduced lung function when z‐scores were used, especially in elderly subjects.This article is protected by copyright. All rights reserved. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 8, 2019 Category: Respiratory Medicine Authors: Barbara Vogt, Victoria Hennig, Kathinka Deu ß, Lorenz Balke, Norbert Weiler, Inéz Frerichs Tags: Original Article Source Type: research