Beyond proteostasis: Roles of type I chaperonins in bacterial pathogenesis.
This article provides a thorough reviews of our current understanding of the different mechanisms involving type I chaperonins during bacteria-host interactions, and suggests new areas to be explored and the potential of finding new targets for fighting bacterial infections. PMID: 30074472 [PubMed - as supplied by publisher] (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - August 3, 2018 Category: Microbiology Authors: Ghazaei C, Line El Helou M Tags: J Med Microbiol Source Type: research

Association of Chlamydophila pneumoniae Infection With Symptomatic Erosive Osteoarthritis of the Hand
No abstract available (Source: JCR: Journal of Clinical Rheumatology)
Source: JCR: Journal of Clinical Rheumatology - July 26, 2018 Category: Rheumatology Tags: Concise Reports Source Type: research

Presence of Chlamydophila pneumoniae DNA in blood cells is a frequent event in patients with the late stage of primary cutaneous lymphomas and with atopic dermatitis.
Conclusions: The presence of C. pneumoniae DNA in the blood cells is a frequent event in late stages of MF/SS and may be explained by Th2 shift and suppression of the immune system during the course of the disease. PMID: 30008645 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - July 18, 2018 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Overview on the management of non-gastric MALT lymphomas
Publication date: March 2018Source: Best Practice & Research Clinical Haematology, Volume 31, Issue 1Author(s): Irene Defrancesco, Luca ArcainiAbstractExtranodal marginal zone B-cell lymphomas (EMZLs) of the mucosa-associated lymphoid tissue (MALT) are indolent lymphomas which can present at any extranodal site. The most frequent localizations (other than stomach) are ocular adnexa, salivary gland, skin, lung and thyroid. Chronic inflammation and antigenic stimulation are a potential risk for the development of MALT lymphomas. While Helicobacter Pylori (HP) is known to be associated with gastric MALT lymphoma and antibioti...
Source: Best Practice and Research Clinical Haematology - July 10, 2018 Category: Hematology Source Type: research

Community-Acquired Pneumonia in Children.
CONCLUSION: In previously healthy children under the age of 5 years, high dose amoxicillin is the treatment of choice. For those with type 1 hypersensitivity to penicillin, clindamycin, azithromycin, clarithromycin, and levofloxacin are reasonable alternatives. For children with a non-type 1 hypersensitivity to penicillin, cephalosporins such as cefixime, cefprozil, cefdinir, cefpodoxime, and cefuroxime should be considered. In previously healthy children over the age of 5 years, macrolides such as azithromycin and clarithromycin are the drugs of choice. PMID: 29932038 [PubMed - as supplied by publisher] (Source: R...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - June 24, 2018 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Pathogen Clearance and New Respiratory Tract Infections Among Febrile Children in Zanzibar Investigated With Multitargeting Real-Time Polymerase Chain Reaction on Paired Nasopharyngeal Swab Samples
Conclusion: The results suggest that children with acute febrile illness in Zanzibar rapidly clear respiratory tract infections but frequently acquire new infections within 14 days. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - June 13, 2018 Category: Infectious Diseases Tags: Original Studies Source Type: research

A Psittacosis Outbreak among English Office Workers with Little or No Contact with Birds, August 2015
Conclusions This investigation into a probable outbreak provides evidence of transmission of psittacosis in one or more office workers with no direct bird contact. In light of this clinicians and public health professionals should be aware of the possibility of psittacosis in cases of severe respiratory illness reporting no overt bird contact and consider it on their list of differential diagnoses in situations where indirect exposure to birds is possible, but not necessarily obvious. Competing Interests The authors have declared that no competing interests exist. Corresponding Author John Mair-Jenkins: john.mairjenkin...
Source: PLOS Currents Outbreaks - April 27, 2018 Category: Epidemiology Authors: John Mair-Jenkins Source Type: research

Immunosuppressive treatment and its impact on the occurrence of Pneumocystis jiroveci, Mycoplasma pneumoniae, Chlamydophila pnemoniae and Legionella pneumophila infections/ colonisations among lung transplant recipients
The aim of the study was to assess the frequency of infections caused by Pneumocystis jiroveci, Chlamydophila pneumoniae, Legionella pneumophila and Mycoplasma pneumoniae among lung transplant recipients in the context of immunosuppression. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - March 13, 2018 Category: Transplant Surgery Authors: Jacek Wojarski, Marek Ochman, Magdalena Latos, Piotr Biniszkiewicz, Wojtek Karolak, El żbieta Woźniak-Grygiel, Marcin Maruszewski, Maciej Urlik, Wojciech Mędrala, Zofia Kułaczkowska, Krzysztof Pyrc, Sławomir Żegleń Source Type: research

[Bacteriology of acute exacerbations of chronic obstructive pulmonary disease in Tunisia].
CONCLUSIONS: Awareness of the low positivity of quantitative sputum bacteriology and the large percentage of resistant strains with a predominance of exclusively multi-resistant Pseudomonas should help in the management of patients with AECOPD. PMID: 29395563 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

Molecular detection of Chlamydophila abortus , Coxiella burnetii , and Mycoplasma agalactiae in small ruminants ’ aborted fetuses in southern Iran
AbstractAbortion in sheep and goats has become increasingly important worldwide because of the significant economic losses and potential zoonotic implication of commonly involved pathogens. Therefore, this cross-sectional study was conducted in southern Iran to detect theChlamydophila abortus andCoxiella burnetii, as zoonotic pathogens, andMycoplasma agalactiae, as a neglected abortifacient agent in small ruminants ’ aborted fetuses, by using polymerase chain reaction (PCR). From a total of 300 aborted fetuses (183 sheep and 117 goats), 46 samples (15.5%) were positive by PCR, 11% forC. abortus, 2% forC. burnetii, and 3%...
Source: Tropical Animal Health and Production - December 19, 2017 Category: Veterinary Research Source Type: research

Overview on the management of non-gastric MALT lymphomas
Publication date: Available online 14 November 2017 Source:Best Practice & Research Clinical Haematology Author(s): Irene Defrancesco, Luca Arcaini Extranodal marginal zone B-cell lymphomas (EMZLs) of the mucosa-associated lymphoid tissue (MALT) are indolent lymphomas which can present at any extranodal site. The most frequent localizations (other than stomach) are ocular adnexa, salivary gland, skin, lung and thyroid. Chronic inflammation and antigenic stimulation are a potential risk for the development of MALT lymphomas. While Helicobacter Pylori is known to be associated with gastric MALT lymphoma and antib...
Source: Best Practice and Research Clinical Haematology - November 15, 2017 Category: Hematology Source Type: research

Overview on the management of non-gastric MALT lymphomas
Extranodal marginal zone B-cell lymphomas (EMZLs) of the mucosa-associated lymphoid tissue (MALT) are indolent lymphomas which can present at any extranodal site. The most frequent localizations (other than stomach) are ocular adnexa, salivary gland, skin, lung and thyroid. Chronic inflammation and antigenic stimulation are a potential risk for the development of MALT lymphomas. While Helicobacter Pylori (HP) is known to be associated with gastric MALT lymphoma and antibiotic therapy is effective in the setting of HP-positive, other microorganisms (such as Chlamydophila Psittaci, Campylobacter Jejiuni, Borrelia Burgdoferi)...
Source: Best Practice and Research. Clinical Haematology - November 14, 2017 Category: Hematology Authors: Irene Defrancesco, Luca Arcaini Source Type: research

Overview on the management of non-gastric MALT lymphomas
Extranodal marginal zone B-cell lymphomas (EMZLs) of the mucosa-associated lymphoid tissue (MALT) are indolent lymphomas which can present at any extranodal site. The most frequent localizations (other than stomach) are ocular adnexa, salivary gland, skin, lung and thyroid. Chronic inflammation and antigenic stimulation are a potential risk for the development of MALT lymphomas. While Helicobacter Pylori is known to be associated with gastric MALT lymphoma and antibiotic therapy is effective in the setting of HP-positive, other microorganisms (such as Chlamydophila Psittaci, Campylobacter Jejiuni, Borrelia Burgdoferi) have...
Source: Best Practice and Research. Clinical Haematology - November 14, 2017 Category: Hematology Authors: Irene Defrancesco, Luca Arcaini Source Type: research