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[Diagnostic uncertainty, working diagnosis and progress of recommendations for pulmonary fibrosis].
Authors: Cottin V, Crestani B, Cadranel J, Marchand-Adam S, Prévot G, Wallaert B, Valeyre D PMID: 29753638 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 15, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[BCG infection following intravesicular immunotherapy for bladder cancer].
CONCLUSION: BCG infection is a rare but not exceptional complication of BCG immunotherapy with heterogeneous clinical presentation. Prospective studies are warranted in order to improve treatment outcomes. PMID: 29754838 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 15, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Retrospective study of 25  cases of pulmonary mucormycosis in acute leukaemia].
CONCLUSION: In AL, early use of CT could improve the prognosis of PM. The presence of a RHS on CT suggests PM and is an indication for prompt antifungal treatment. PMID: 29754839 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 15, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Respiratory physiotherapy in acute viral bronchiolitis in the newborn. Pro/con arguments].
This article reports an exchange of unbiased arguments between Mr Guy Postiaux speaking in favour of respiratory physiotherapy in acute viral bronchiolitis in the newborn and Prof. Jean-Christoph Dubus arguing against. A review of the literature suggests that traditional methods of physiotherapy should be abandoned because they are not validated and because they have harmful side effects. The latest Cochrane revue (2016) suggests the use of slow expiration techniques that have some validated elements and cause no harmful side effects. Large multicentre studies should be undertaken to confirm or refute the results of the fi...
Source: Revue des Maladies Respiratoires - May 15, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Risks associated with the use of non-steroidal anti-inflammatory drugs during pneumonia].
CONCLUSIONS: Intake of NSAIDs during outpatient treatment of CAP is probably the second modifiable factor of morbidity after inadequate antibiotic therapy. In light of existing data in children and adults, health authorities should urgently reassess the risk-benefit ratio of NSAIDS in CAP. PMID: 29754841 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 15, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Lungs and fungi: level of evidence and doubts].
Authors: Godet C, Cadranel J PMID: 29754842 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 15, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Altitude and the right heart].
CONCLUSIONS: Altitude may be a cause of right heart failure. This uncommon complication of altitude exposure requires further epidemiological and therapeutic studies. PMID: 29748074 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 12, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Diagnosis of idiopathic pulmonary fibrosis: A bed of roses?]
Authors: Naccache JM, Nunes H PMID: 29739661 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - May 11, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Inhaled chemotherapy -  Part 1: General concept and current technological challenges].
[Inhaled chemotherapy - Part 1: General concept and current technological challenges]. Rev Mal Respir. 2018 May 03;: Authors: Rosière R, Hureaux J, Levet V, Amighi K, Wauthoz N Abstract Despite severe adverse effects, chemotherapy is still widely used in the treatment of lung tumors, including primary lung tumors and metastases. In order to reduce the risk of harm and to intensify treatment responses, several strategies have been described recently. These include the use of nanomedicine-based chemotherapies and pulmonary drug delivery. However, to treat lung tumors, inhalation cannot be eff...
Source: Revue des Maladies Respiratoires - May 10, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Environmental exposure chambers (EEC): A novel tool for pathophysiological and pharmaceutical research].
Authors: Khayath N, Radu C, Choual I, Jilani S, Vecellio L, Domis N, De Blay F Abstract Airborne allergic diseases (allergic asthma, rhinitis and conjunctivitis) have reached epidemic proportions and are a great burden for both society and individuals. Therefore we need to better understand the physiopathological mechanisms and to increase clinical research in these diseases. However, traditional outpatient studies are difficult and have number of limitations, in particular the variability of allergen exposure. Yet allergen provocation tests, especially bronchial challenges in asthma, are excellent tools to measure...
Source: Revue des Maladies Respiratoires - May 10, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Inhaled chemotherapy - Part 2: Clinical practice and potential applications].
Authors: Rosière R, Hureaux J, Levet V, Amighi K, Wauthoz N Abstract Lung tumours have a high incidence and cause many deaths worldwide. Despite progresses in treatment with targeted therapies and immunotherapies, the global 5-year survival rate remains low. In this context, inhaled chemotherapy could provide a means to intensify current therapeutic modalities. This review is based on clinical studies of inhaled chemotherapy against lung tumours. The advantages of this approach in terms of pharmacokinetic ratio and therapeutic index are presented as well as the limitations including contraindications and pul...
Source: Revue des Maladies Respiratoires - May 10, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Can PFTs still be interpreted based on fixed limits of normality?]
Authors: Dessanges JF, Baud D, Charloux A, Plantier L PMID: 29699777 [PubMed - in process] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 28, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Lower limit of normal vs. fixed ratio for the diagnosis of COPD: Is it that important?]
Authors: Burgel PR PMID: 29699778 [PubMed - in process] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 28, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Tuberculous pseudotumour, a challenging diagnosis].
CONCLUSION: Making a positive diagnosis of thoracic tuberculous pseudotumour can be difficult, as bacteriological samples are often negative. This can lead to a significant delay in diagnosis and treatment. PMID: 29627293 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 10, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Persistent asthma: Chronic therapy quantitative compliance in daily practice].
Authors: Devillier P, Ghasarossian C, Terrioux P, Schiratti M, Leutenegger E Abstract INTRODUCTION: The aim of the study was to assess, compliance with maintenance treatment in patients with persistent asthma in clinical practice. METHODS: This observational, cross-sectional, prospective, multicenter study was conducted in metropolitan France on patients with persistent asthma under the care of a representative sample of general practitioners and pneumologists. Compliance was determined via access to the Health Insurance database allowing comparison between the actual consumption of medications and the correspo...
Source: Revue des Maladies Respiratoires - April 4, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Study of the feasibility of spirometry in general practice].
Authors: Bunge L, Baruch D, Plantier L, Mazars T, Roche N, Izadifar A, Médiflux Abstract COPD is common but is under-diagnosed by general practitioners (GP). GP have a major role in the early diagnosis of this disease. GP could have access to spirometry. The aim of this study was to evaluate the quality and interpretation of spirometry performed by primary care residents following a short education session. Three residents were trained in spirometry for half a day. They then performed spirometry on all smokers over the age of 35 visiting five general practices. The results were reviewed blindly by an in...
Source: Revue des Maladies Respiratoires - April 3, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Post-traumatic pulmonary aspergilloma].
CONCLUSIONS: This clinical case illustrates the benefits of surgical management of post-traumatic aspergillomas, even in children, in order to eradicate the aspergillus implant and to remove any foreign body to prevent recurrence. PMID: 29602478 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Asthma and socioeconomic characteristics in France in 2012].
CONCLUSIONS: These results show that subjects with lower socio-economic status are more likely to suffer from asthma. New epidemiological tools in France, including cohorts (Constances, COSET) will be helpful to study more precisely the associations between asthma and occupational factors. PMID: 29602479 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Tunnelled central venous catheter infection during treatment with epoprostenol].
CONCLUSION: Infection of a tunneled intravenous catheter should be considered in the case of non-specific symptoms or where there is evidence of sepsis, in patients treated with intravenous prostacyclin analogues administered intravenously. In this context, the laboratory should be warned to search for slow-growing organisms. PMID: 29602480 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Asthma: Adapting the therapeutic follow-up according to the medical and psychosocial profiles].
CONCLUSIONS: Cluster analysis provides a multidimensional approach to understand the therapeutic behavior of the different patient profiles better and so adjust communication by and education of healthcare professionals. PMID: 29602481 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Neurofibromatosis as a cause of breathlessness].
CONCLUSIONS: Our observation shows the complexity of the therapeutic support of the neurofibromatosis of type 1. The contribution of non-invasive ventilation was illustrated by the arterial blood gas and clinical improvements as well as improved quality of life, with an acceptable level of inconvenience to the patient. PMID: 29602482 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Spotting the GLObalRIsk of severe outcomes in undiagnosed COPD patients (GLORI-COPD)].
Authors: Malmartel A, Eap D, Ghasarossian C Abstract BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a severe chronic disease and its prevalence is increasing. Nevertheless, mortality linked to moderate and mild COPD without comorbidities is low. The aim of the study is to create and validate a questionnaire in primary care to spot patients with undiagnosed COPD who are at high risk of severe complications considering the severity of their COPD and their comorbidities. METHODS: The development of the questionnaire has three steps. The first is the selection of the items which can be included in the ...
Source: Revue des Maladies Respiratoires - April 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Blue rubber bleb naevus syndrome involving the pleura].
We report the case of an asbestos-exposed patient with Bean's syndrome with characteristic skin lesions, smoker, hospitalized for the investigation of a hemorrhagic pleural effusion. A medical thoracoscopy revealed pleural lesions similar to the cutaneous lesions and compatible with a pleural localization of the disease. This is the first documented case of this disease involving the pleura. A review of the literature was carried out on account of this clinical case. PMID: 29602484 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - April 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Occurrence of delayed symptoms after a challenge test with methacholine].
The objective of this study was to describe the nature and frequency of respiratory symptoms suggestive of bronchospasm developing within 24hours after a MCT. The study was offered to adult patients who underwent MCT seen consecutively between June and October 2015. Following the test, a questionnaire adapted from the GINA asthma control questionnaire bearing on diurnal and nocturnal symptoms (cough, dyspnoea, wheeze and tightness), was delivered to the patient and the replies collected by telephone 24hours later. Of the 101 patients included (initial FEV1 2.82±0.79L), 46 (46 %) were MCT+ and 55 (54 %...
Source: Revue des Maladies Respiratoires - April 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[SaO2 and PaO2 mismatch: Do not forget hemoglobinopathy].
CONCLUSION: The diagnosis of hemoglobinopathy should be considered in cases of oxygen desaturation with normal respiratory and cardiac investigations. There are no reasons to prescribe long-term oxygen to these patients. PMID: 29580615 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - March 29, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Influenza vaccination and cystic fibrosis. Impact of an incentivisation campaign about influenza vaccination for patients attending the Dunkerque cystic fibrosis treatment centre and their health care workers].
Authors: Scalbert-Dujardin M, Boldron A, Leroy E, Bazin J, Froment-Leclercq E Abstract INTRODUCTION: The main aim of this study is to evaluate the effectiveness of preventive actions regarding influenza in the studied populations. The secondary objective is to analyze and understand the mechanisms which bring about a behavioural change regarding influenza vaccination. METHODS: The interventional and prospective study was undertaken in the form of an anonymous questionnaire about influenza vaccination coverage and about the reasons for vaccinating or not vaccinating. The studied populations were patients followe...
Source: Revue des Maladies Respiratoires - March 29, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Evolution and revolution in systemic treatment of lung cancer. The new role of immunotherapy].
Authors: Duruisseaux M, Berghmans T PMID: 29548518 [PubMed - in process] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - March 22, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Pulmonary veno-occlusive disease].
Authors: Boucly A, Girerd B, Bourlier D, Nemlaghi S, Caliez J, Savale L, Jaïs X, Dorfmüller P, Simonneau G, Sitbon O, Humbert M, Montani D Abstract Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension (PH) characterized by preferential remodelling of pulmonary venules and angioproliferation. PVOD term includes idiopathic, heritable (biallelic mutations of EIF2AK4 gene), drugs and toxins induced (alkylating agents, organic solvents) and connectivite-associated forms (especially systemic-sclerosis associated form). PVOD and pulmonary arterial hypertension (PAH) share a simil...
Source: Revue des Maladies Respiratoires - March 5, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Asthma and the microbiome].
CONCLUSION: The implication of the microbiome in the pathogenesis of human asthma seems to be more and more likely. This could have possible therapeutic implications, notably the restoration of a healthy microbiome. PMID: 29482867 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - March 1, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Outdoor moulds and respiratory health].
Authors: Caillaud D, Cheriaux M, Charpin D, Chaabane N, Thibaudon M Abstract Mould spores constitute the largest portion of biologic particulate matter suspended in the outdoor atmosphere. There is no universal method for collecting airborne mould spores. The most used sampler, Hirst's apparatus, operates continuously and gives results in individual spores per cubic metre of air. Spore concentrations depend on available substrates, human activities such as agriculture, season, diurnal meteorological variations and climate changes. Under natural conditions, concentrations of over 100,000 spores per cubic metre ...
Source: Revue des Maladies Respiratoires - February 27, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Invasive pulmonary aspergillosis].
CONCLUSIONS: IPA must be considered in a wide range of patients. Its prognosis remains poor despite progress in the microbiological diagnosis and therapeutic management. PMID: 29478757 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 27, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Is celecoxib a safe alternative for the Fernand Widal syndrome?]
Authors: Schaller A, Metz-Favre C, Guenard-Bilbaut L, De Blay F Abstract The Fernand Widal syndrome is a set of associations between asthma, nasal polyposis and aspirin sensitivity. Selective cyclo-oxygenase 2 (COX 2) inhibitors are recognized as being a therapeutic alternative in cases needing analgesic or anti-inflammatory treatment. In a retrospective study, we have compiled data concerning oral provocation tests (OPT) undertaken with celecoxib, one of most the selective COX 2 inhibitors, in eight patients with the Fernand Widal syndrome. They were compared with twenty-seven control patients with sensi...
Source: Revue des Maladies Respiratoires - February 23, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Alveolar hemorrhage and cocaine use].
Authors: Underner M, Perriot J, Wallaert B, Peiffer G, Meurice JC, Jaafari N Abstract In France, cocaine is the second most commonly illicit drug used after cannabis. Cocaine, mainly smoked in the form of crack, can be responsible for a wide range of respiratory disorders. The aim of this systematic literature review was to clarify what is known about the link between cocaine use and alveolar hemorrhage. We performed a Medline search covering the period 1980-2016 and collected data from 84 articles. The number of acute forms described in the literature is small but postmortem studies show that hidden form...
Source: Revue des Maladies Respiratoires - February 22, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Sleepiness, continuous positive airway pressure and the obstructive sleep apnea hypopnea syndrome].
Authors: Lerousseau L Abstract Excessive daytime sleepiness is a major symptom in cases of the obstructive sleep apnea-hypopnea syndrome. Most often, it is vastly improved by treatment with continuous positive airway pressure (CPAP). The most effective way to confirm its disappearance is through wakefulness maintenance testing. If residual sleepiness remains, despite CPAP, further diagnostic investigation must be carried out. Firstly, it must be assessed whether the treatment is fully effective (apnea hypopnea index6h/night). If this is the case, the possibility of other situations responsible for excessive daytime...
Source: Revue des Maladies Respiratoires - February 20, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[The biological rationale for immunotherapy in cancer].
CONCLUSIONS: Numerous challenges still remain in developing research approaches for the development of immunotherapies. PMID: 29428191 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 14, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[DRESS syndrome secondary to pyrazinamide: An uncommon complication of tuberculosis treatment].
CONCLUSIONS: Discovery of DRESS syndrome during tuberculosis treatment is an uncommon complication and requires a searching for the responsible drug. That should be difficult because tuberculosis drugs are often given as fixed-dose combination. Physicians have to bear in mind the potential role of pyrazinamide. PMID: 29429561 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 14, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Anti-tumor immunotherapy in malignant pleural mesothelioma].
CONCLUSIONS: However, several exciting immunotherapies other than ICI are presently being evaluated in MPM and are reported in this article. Moreover, many questions still need to be answered about immunotherapy: what is its potential value as first line treatment? How to target the best candidates for these treatments? Which combinations between immunotherapy and standard chemotherapy, targeted therapies, surgery or radiotherapy? Finally, it is now essential that every clinician has sufficient knowledge about the possible toxicities of immunotherapy. PMID: 29415822 [PubMed - as supplied by publisher] (Source: Revue de...
Source: Revue des Maladies Respiratoires - February 10, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Effect of a surgical mask on six minute walking distance].
Authors: Person E, Lemercier C, Royer A, Reychler G Abstract INTRODUCTION: Six minutes walking test (6MWT) is regularly used in pulmonology. To minimize the risk of cross-infection, some patients must wear surgical mask at rest and sometimes during exercise. AIM OF THE STUDY: To evaluate the effect of wearing a surgical mask during 6MWT in healthy subjects. MATERIAL AND METHOD: It is a prospective study on 44 healthy subjects. After a first 6MWT for training, they performed randomly two 6MWT: with or without a surgical mask. Distance and dyspnea, heart rate and saturation variations were recorded. ...
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Tracheostomy performed in ICU: Professional practice assessment and patient outcome].
CONCLUSION: Young patients weaning from mechanical ventilation were more likely to receive a tracheostomy. More than half died during the first year. Patients discharged from ICU with a tracheostomy tube in place had higher mortality rate. PMID: 29395561 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Endobronchial ultrasound with transbronchial needle aspiration: Evaluation of clinical practice].
CONCLUSION: A continuous increase in the number of EBUS-TBNA procedures was observed during the period 2008-2013. It was associated with a modification in practice with an increased proportion of procedures performed for the diagnosis of sarcoidosis. PMID: 29395562 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Bacteriology of acute exacerbations of chronic obstructive pulmonary disease in Tunisia].
CONCLUSIONS: Awareness of the low positivity of quantitative sputum bacteriology and the large percentage of resistant strains with a predominance of exclusively multi-resistant Pseudomonas should help in the management of patients with AECOPD. PMID: 29395563 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Cohort of patients initiated to home ventilation. Observational and prospective study].
Authors: Rabec C, Gonzalez-Bermejo J, Cuvelier A, Cervantes P, Foret D, Mounier L, Melloni B, Muir JF Abstract Cohort of patients initiated to home ventilation. Observational and prospective study. The effectiveness of home noninvasive ventilation (NIV) for chronic respiratory failure (CRF) is well established. However, few data are available about home NIV prescription and utilization according to the different etiologies of respiratory failure. The ANTADIR Federation, in partnership with the Ventilatory Support Group of the French Speaking Pulmonary Society, has set up a national, observational and multicenter co...
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Rigid bronchoscopy].
Authors: Briault A, Dutau H PMID: 29395565 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Clinical and radiological characteristics of pulmonary tuberculosis in tobacco smokers].
Authors: Kombila UD, Mbaye FBR, Dia Kane Y, Ka W, Toure Badiane NO Abstract INTRODUCTION: Tobacco smoke alters lung defense mechanisms against infections and so increases the risk of mycobacterium tuberculosis infection. OBJECTIVE: To determine the particular clinical features of tuberculosis in smokers and identify risk factors. METHODS AND PATIENTS: We conducted a prospective, cross-sectional study over a period of nine months in Dakar, Senegal. The Chi-square test and multiple logistic regression were used to identify differences between smokers and non-smokers and to identify factors associated with cli...
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Immune checkpoint inhibitors (antibodies to PD1 and PD-L1), a new therapeutic weapon against non-small cell bronchial carcinoma].
CONCLUSIONS: These new drugs now constitute a standard second-line treatment for metastatic tumours and in the future, at least for pembrolizumab, in the first line. Their adjuvant role after locoregional treatment with curative intent is currently under investigation. PMID: 29395567 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Pulmonary granuloma in an immunodepressed patient].
CONCLUSION: Outside endemic areas and in the absence of hepatic involvement pulmonary alveolar echinococcosis can be difficult to diagnose. This case report focuses on the diagnostic criteria and treatment. PMID: 29395568 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Vocal cord dyskinesia and/or asthma].
CONCLUSIONS: VCD remains under-appreciated and misdiagnosed, often by mimicking asthma with which it can be associated. A delayed diagnosis by emergency specialists, pulmonologists and ear nose and throat surgeons leads to unnecessary treatments and morbidity before specific therapy can be given. PMID: 29397301 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Smoking attitudes and behavior of the hospital staff Sahloul (Sousse, Tunisia)].
CONCLUSION: Confronted with the problem of tobacco, health institutions should find solutions for the prevention of smoking in hospitals. It seems necessary to train and involve hospital staff in anti-tobacco measures and to help smokers to quit in order to make our hospital a tobacco smoke free space. PMID: 29397302 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Impact of routine brain imaging in the initial management of lung cancer].
CONCLUSION: The addition of brain imaging in the initial assessment of bronchial carcinoma allows the identification of brain metastases in one case among 5, of which 2/3 are asymptomatic. This leads to a change in staging, primarily for disease otherwise considered to be stage III. PMID: 29397303 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research

[Interstitial lung disease and pancreatic cancer: Series of two cases].
CONCLUSION: Where atypical interstitial lung disease occurs, biopsy should be considered in order not to delay a diagnosis of cancer, especially pancreatic cancer. PMID: 29398155 [PubMed - as supplied by publisher] (Source: Revue des Maladies Respiratoires)
Source: Revue des Maladies Respiratoires - February 7, 2018 Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research