Angioedema. Interdisciplinary diagnostic and therapeutic recommendations of the Polish Dermatological Society (PTD) and Polish Society of Allergology (PTA).
Authors: Nowicki RJ, Grubska-Suchanek E, Porêbski G, Kowalski ML, Jahnz-Różyk K, Matuszewski T, Rudnicka L, Kulus M, Barañska-Rybak W, Czajkowski R, Doniec Z, Kowalewski C, Krêcisz B, Lange M, Narbutt J, Olszewska M, Sokołowska-Wojdyło M, Szczerkowska-Dobosz A, Śpiewak R, Trzeciak M, Wilkowska A Abstract Angioedema is a non-inflammatory oedema of the subcutaneous tissue and/or mucosal membranes. It most commonly coexists with urticaria wheals and is considered to be a deep form of urticaria. Less commonly, it occurs in isolation and can take two basic forms: acquired angioedema and her...
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Pathogenesis of psoriasis in the "omic" era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis.
Pathogenesis of psoriasis in the "omic" era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis. Postepy Dermatol Alergol. 2020 Aug;37(4):452-467 Authors: Owczarczyk-Saczonek A, Purzycka-Bohdan D, Nedoszytko B, Reich A, Szczerkowska-Dobosz A, Bartosiñska J, Batycka-Baran A, Czajkowski R, Dobrucki IT, Dobrucki LW, Górecka-Sokołowska M, Janaszak-Jasiecka A, Kalinowski L, Krasowska D, Radulska A, Reszka E, Samotij D, Słominski A, Słominski R, Sobalska-Kwapis M, Stawczyk-Macieja M, Strapagiel D, Szczêch J, Żmijewski M, Nowicki RJ Abstract Psoriasis is ...
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Non-alcoholic fatty liver disease in patients with psoriasis: therapeutic implications.
Authors: Klujszo EH, Parcheta P, Witkowska AB, Krecisz B Abstract Non-alcoholic fatty liver disease (NAFLD) is the most common liver pathology in the western countries. Psoriatic patients are at higher risk of having NAFLD, and at higher risk of experiencing a more severe form of the disease with poorer outcomes. The components of the metabolic syndrome - obesity, lipid abnormalities, hypertension, and type 2 diabetes - significantly correlate with NAFLD progression. The inflammatory state present in psoriasis plays a significant role in development of NAFLD and the metabolic syndrome. All patients with psoriasis a...
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Low-level laser therapy in the treatment of recurrent aphthous stomatitis and oral lichen planus: a literature review.
Authors: Ślebioda Z, Dorocka-Bobkowska B Abstract Recurrent aphthous stomatitis (RAS) and oral lichen planus (OLP) present inflammatory, recurrent diseases of the oral mucosa with not fully understood aetiology. Despite numerous attempts to discover an effective treatment for RAS and OLP, the current main treatment strategies are largely confined to the reduction of symptoms. Low-level laser therapy (LLLT) is of interest as a novel treatment modality. The aim of the paper was to discuss the mechanism of action and the biological effects of LLLT and to critically review and summarize recent clinical reports on the ...
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Frontal fibrosing alopecia: a disease that remains enigmatic.
Authors: Lis-Święty A, Brzezińska-Wcisło L Abstract Frontal fibrosing alopecia (FFA) is recognized to represent a generalized process of inflammatory scarring alopecia. Apart from the classic form affecting the frontal hairline, there are a range of disease manifestations involving loss of eyebrows and of eyelashes, loss of peripheral body hair, fibrosing alopecia in a pattern distribution, facial and extrafacial skin, mucous membrane, and nail involvement. Classic linear, diffuse "zigzag", pseudo "fringe sign", androgenetic alopecia-like, cockade-like, ophiasis-like and incomplete patterns ...
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Dermoscopic diagnosis of subungual hematoma: new observations.
Conclusions: We detected two new findings which have not been described previously for subungual hematoma: the first one is "blue-white colour" which is known as an important clue to melanoma. The second one is granular leukonychia localized on the hematoma. We suggest that in any case of the nail discoloration, a thorough dermoscopic examination should be performed. Moreover, progression of the colour change to the distal edge should be observed to ensure that a possible melanoma is not overlooked. PMID: 32994768 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Endothelial dysfunction in patients with systemic sclerosis.
Authors: Pacholczak-Madej R, Kuszmiersz P, Bazan-Socha S, Kosałka-Wêgiel J, Iwaniec T, Zarêba L, Kielczewski S, Rams A, Walocha JA, Musiał J, Dropiñski J Abstract Introduction: Patients with systemic sclerosis experience endothelial dysfunction and damage even in the absence of clinical manifestations. Aim: To evaluate various methods for assessing the endothelial function for their applicability to clinical practice. Material and methods: Forty-two patients (7 men and 35 women) with systemic sclerosis and 36 controls (11 men and 25 women) matched for age, sex, body mass index, smoking ...
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

The role of pentraxin 3 in pemphigus vulgaris.
Conclusions: PTX3 was found to be increased in PV and PTX3 could be a useful indicator of disease activity in PV. PMID: 32994770 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Sensitisation to lipid transfer proteins in pollen - allergic adults with food allergy.
Conclusions: Antigen-specific IgE antibodies to LTP components were identified in 24% of the subjects. In subjects with LTP allergy, adverse skin reactions were the most common after consumption of sensitising foods. Peach was the most common food allergen triggering these reactions. The Artemisia vulgaris component Art v 3 was the precursor of LTP allergy in our study population: the highest incidence and the highest mean levels of asIgE were demonstrated for this component. PMID: 32994771 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

In silico analysis of CpG islands and miRNAs potentially regulating the JAK-STAT signalling pathway.
Conclusions: The epigenetic mechanisms of the regulation of the JAK-STAT signalling pathway gene expression constitute a promising new therapeutic strategy for treatment of those diseases, during which disorders are observed in gene expression models of the analysed signalling pathway. PMID: 32994772 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Oral premedication in patients with a history suggesting hypersensitivity to iodinated contrast media.
Conclusions: Premedication with cetirizine and prednisone before radiologic procedures proved to be efficient in patients with a history suggesting hypersensitivity to iodinated contrast media. There was no significant difference in efficacy related to the dose of prednisone (20 mg vs. 50 mg). PMID: 32994773 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Factors affecting the concentration of soluble tumour necrosis factor- α receptor type I in the blood serum of patients with localized scleroderma.
Conclusions: The obtained results suggest a potential role of sTNFαR1 in the pathogenesis of localized scleroderma. PMID: 32994774 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Diagnostic accuracy of reflectance confocal microscopy for pigmented skin lesions presenting dermoscopic features of cutaneous melanoma.
Conclusions: It can be estimated that double evaluation of melanocytic lesions by dermoscopy and reflectance confocal microscopy may allow up to 62% of unnecessary excisions to be avoided. PMID: 32994775 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Caspase-3, p53 and Bcl-2 expression in basal cell carcinoma of the eyelid.
Conclusions: The caspase-3 level was lower in the BCC group. This result suggests that these enzymes can play a significant role in carcinogenesis of eyelid BCC. PMID: 32994776 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Prevalence of allergic rhinitis and asthma in Poland in relation to pollen counts.
Conclusions: Our findings do not confirm the hypothesis of a positive association between pollen exposure and the prevalence of allergic rhinitis and asthma. PMID: 32994777 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Efficiency of long-term high-dose intravenous ascorbic acid therapy in locally advanced basal cell carcinoma - a pilot study.
Conclusions: Our results suggest that IVA is well tolerated in a small group of patients with extensive BCCs. However, in the era of smoothened (Smo) receptor inhibitors, it may only be considered as an adjuvant therapy in treatment-resistant cases. PMID: 32994778 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Bronchial asthma control degree and the temperament structure according to the Eysenck model.
Conclusions: The structure of temperament of a person with poor control of bronchial asthma can be characterized. Patients with poor asthma control have a higher level of neuroticism, psychoticism and propensity to lie, compared with the healthy population and subjects with good or partial bronchial asthma control. PMID: 32994779 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Effect of Oreodoxa oleracea Jacq. pollen protein allergen in albino mice.
Conclusions: The present study is the first study to evaluate the allergenic potential of Oreodoxa oleracea in mice. The findings revealed that Oreodoxa oleracea which is profoundly planted in pubic areas for aesthetic purposes possess allergenic effect. PMID: 32994780 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Usefulness of three-dimensional digital image analysis for objective evaluation of the efficacy of non-facial port-wine stain treatment with large spot 532 nm laser.
Conclusions: Both objective and subjective analysis indicated that the large spot 532 nm laser is highly effective in the treatment of the neck and trunk. 3D color and area objective analysis provides an accurate tool to measure the efficacy of PWS treatment. PMID: 32994781 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Assessment of selected parameters of the circulatory system in patients undergoing oral aspirin challenge.
Conclusions: No clinically significant cardiac arrhythmias were recorded during OAC. The changes observed in the records of blood pressure and ECG monitoring show that OAC performed in accordance with the current guidelines does not pose a high risk to the patient's health and life as a result of cardiovascular reactions. PMID: 32994782 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Vascular endothelial growth factor-activated basophils in asthmatics.
Conclusions: Raised basophils VEGF-activation is characteristic for examined patients with asthma and might be associated with presence of polymorphism del18/ins -2549 -2567 in the VEGF-promoter region. Furthermore, it may contribute to the development of airways remodelling - this pathway has not been considered yet. PMID: 32994783 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Expression of eosinophils, RANTES and IL-25 in the first phase of Hymenoptera venom immunotherapy.
Authors: Pałgan K, Żbikowska-Götz M, Bartuzi Z Abstract Introduction: Venom immunotherapy (VIT) can protect against severe anaphylactic reactions (SR) in 80-100% of subjects allergic to Hymenoptera venom. The mechanisms of induction of immunological tolerance produced by VIT are still little known. It has been shown that VIT modulates Treg activity, Th2 or Th1 cells or both, increases production of IL-10, decreases secretion of IL-13, and causes an IgG4/IgE ratio shift. Aim: To investigate the blood eosinophil count, CCL5/RANTES and IL-17E/IL-25 concentrations before and after the initial phases of the r...
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Relationship between self-esteem and stigmatization in psoriasis patients.
Conclusions: Our findings demonstrate clearly that both self-esteem and stigmatization are significant components of psoriasis' influence on the patient life. Psoriasis should not be considered merely as a somatic problem, but also as a significant psychological and social burden. PMID: 32994785 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Treatment of haemangiomas using propranolol in paediatric patients: a retrospective cohort study.
Conclusions: After achieving the maximum dose of the drug later than recommended in the Recommendation of the Polish Haemangioma and Vascular Malformations Group criteria, there was no need for longer therapy, while the effectiveness of the treatment remained unchanged. Side effects that occurred were not life-threatening or detrimental to the health of patients. PMID: 32994786 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Participation of the coagulation system and fibrinolysis as well as selected biomarkers in pathogenesis of chronic urticaria with various activity degree.
Authors: Obtułowicz A, Migacz-Gruszka K, Pirowska M, Basta-Klonowska K, Wojas-Pelc A Abstract Introduction: Chronic urticaria is a complex disease process in which chronic spontaneous urticaria (CSU) and chronic inducible urticaria are distinguished. Its etiopathogenesis still remains unknown. Some recent studies indicated a significant participation of vitamin D in the etiopathogenesis of urticaria. In 40-50% of patients with CSU on the basis of the positive result of the autologous serum skin test (ASST), autoimmunological background of the disease is diagnosed. Moreover, numerous test results confirm involvemen...
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

55-year old woman with erysipelas.
Authors: Plagens-Rotman K, Przybylska R, Gerke K, Adamski Z, Czarnecka-Operacz M PMID: 32994788 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - October 2, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Ocular manifestations of dermal paraneoplastic syndromes.
Authors: Zdebik A, Lantzsch H, Buhles N, Zdebik N Abstract Dermal paraneoplastic syndromes are non-malignant disorders, caused indirectly by the increase in growth factors or as immunological reactions, which lead to a variety of inflammatory, hyperkeratotic or proliferative skin reactions. They can occur as facultative or obligate paraneoplastic dermatoses, which are associated with oncological processes (solid tumours or hematologic diseases). The recognition of paraneoplastic skin disorders can accelerate proper diagnosis and determine better prognosis for the patient and is also important to clinicians because ...
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

The ambiguous pruritogenic role of interleukin-31 in cutaneous T-cell lymphomas in comparison to atopic dermatitis: a review.
Authors: Olszewska B, Sokołowska-Wojdyło M, Lakomy J, Nowicki RJ Abstract Cutaneous T-cell lymphomas (CTCLs) comprise a group of chronic heterogeneous diseases of unknown pathogenesis, characterized by non-specific skin lesions such as patches, plaques and tumours. CTCL is accompanied by persistent pruritus poorly responding to antihistamines and therefore significantly reducing quality of life in patients with lymphomas. According to research data, interleukin-31 (IL-31) contributes to initiation and maintenance of the inflammatory process of the skin and pruritus in inflammatory dermatoses such as atopic dermat...
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Factors causing oral and skin pathological features in the hyperimmunoglobulin E syndrome patient including the environmental component: a review of the literature and own experience.
Authors: Gerreth K, Szczawinska-Poplonyk A, Kycler Z, Adamski Z, Borysewicz-Lewicka M, Breborowicz A Abstract The hyperimmunoglobulin E syndrome (HIES) is a rare multi-system disease with non-immunological as well as immunological abnormalities. The syndrome is characterized by a triad of the most distinctive symptoms, such as pneumonia with pneumatocele formation, recurring staphylococcal skin abscesses and a high serum concentration of IgE. Central mediators of immune responses such as STAT1 and STAT3 affect immune responses and contribute to changes of the skin microbiome which subsequently can amplify the defec...
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Trace elements and oxidative stress status in patients with psoriasis.
Conclusions: Some trace element levels and oxidant-antioxidant balance were changed in psoriasis patients. PMID: 32792872 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Trichoscopic findings of trichotillomania: new observations.
Conclusions: Here we have documented trichoscopic findings of TTM retrospectively. Trichoptilosis, V hair and hair powder were the most frequent relatively specific findings. We tried to define novel findings that we named branched hair and concentric hair. We also detected Mace hair in 9 cases. Mace hair was previously described just in 3 cases of TTM in a case study. Angulated hairs, to the best of our knowledge, were also firstly described for TTM in the present study. Lack of a comparison group is the main limitation of the study. PMID: 32792873 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Biochemical and histopathologic assessment of effects of acitretin on epiphyseal growth plate in rats.
Conclusions: Our data show that though acitretin caused degeneration of the epiphyseal plate, it did not cause clear thinning and we identified no significant variations in bone metabolism markers. PMID: 32792874 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Age-related changes in elastographically determined strain of the facial fat compartments: a new frontier of research on face aging processes.
Authors: Paluch Ł, Pietruski P, Kwiek B, Noszczyk B, Ambroziak M Abstract Introduction: Our study goal was verification of shear-wave elastography (SWE) as an assessment tool enabling quantitative analysis of facial fat tissue elasticity, using the example of the deep medial cheek fat compartment (DMCFC), due to its major role in pseudoptosis etiology. Aim: Furthermore, we determined the age-specific reference values for DMCFC elasticity and analyzed its correlation with body mass index (BMI) and DMCFC thickness. Material and methods: The study included 89 female patients (age: 18-63 years, mean: 45.9 &plu...
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Assessment of auditory function and lipid levels in patients receiving oral isotretinoin (13-cis retinoid) therapy for acne vulgaris.
Conclusions: According to our study findings, isotretinoin did not cause worsening of the bilateral hearing threshold, but increased blood lipid levels. There is no need for follow-up auditory functions in routine practice during therapy, but blood lipid levels should be monitored. PMID: 32792876 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Clinical usefulness of high-frequency ultrasonography in the monitoring of basal cell carcinoma treatment effects.
Authors: Raszewska-Famielec M, Borzêcki A, Krasowska D, Chodorowska G Abstract Introduction: To date, there has been no consensus either on the method, frequency or total duration of follow-up for patients that have developed a basal cell carcinoma (BCC). Aim: To evaluate usefulness of high-frequency ultrasound in monitoring patients with BCC, particularly to detect residual disease or early recurrence. Material and methods: Seventy-eight patients with suspicious lesions of BCC were enrolled in this study. Only patients for whom histologic evaluation confirmed diagnosis of BCC (70) continued the study...
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Intra-rater reproducibility of shear wave elastography in the evaluation of facial skin.
Conclusions: Shear wave elastography is a reliable method for the evaluation of facial skin elasticity, providing highly reproducible results in all patients, regardless of their age and body weight. PMID: 32792878 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Short-term effects of air pollution on exacerbations of allergic asthma in U žice region, Serbia.
Conclusions: Exposure to ambient air pollution in the Užice region increases the risk of ED visits for asthma, particularly during the heating season. PMID: 32792879 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Can allergy patch tests with food additives help to diagnose the cause in childhood chronic spontaneous urticaria?
Conclusions: There can be an association between food additives and CSU. APT tests may be a helpful tool in the assessment and management of CSU so that easier to follow diets and effective treatments can be offered to families. PMID: 32792880 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Evaluation of contact sensitivity to food additives in children with atopic dermatitis.
Conclusions: In our study, contact sensitivity was detected more frequently in AD patients. Food additives may play a role in the development and exacerbation of AD. Atopy patch testing with food additives can be useful in the treatment and follow-up of children with AD. PMID: 32792881 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Uncovering subtle nail involvement in lichen planus with dermoscopy: a prospective, controlled study.
Authors: Elmas ÖF Abstract Introduction: There are very few studies investigating the dermoscopic aspect of nail involvement in lichen planus and these studies described dermoscopic features of only clinically visible nail involvement in lichen planus. Aim: To reveal subtle dermoscopic nail findings in patients with lichen planus. Material and methods: The study included 40 patients with lichen planus and 40 healthy volunteers. All fingernails of the patients and healthy volunteers were examined by a handheld dermoscope and the findings detected were recorded. The patients were grouped by age, gender, ...
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Effect of methotrexate treatment on the expression of epidermal-fatty acid-binding protein (E-FABP) and apolipoproteins in patients with psoriasis.
Authors: Owczarczyk-Saczonek A, Czerwiñska J, Orylska M, Placek W Abstract Introduction: Epidermal-fatty acid-binding protein (E-FABP) is a marker of transiently amplifying cells which are formed from stem cells in epidermis. Their role is an uptake of fatty acids and metabolism. Psoriatic keratinocytes overexpress E-FABPs, which leads to acanthosis and may explain the lipid's disturbances in psoriasis. Aim: Assessment of FABP and apolipoprotein expression in patients treated with methotrexate (MTX). Material and methods: FABP expression in the lesional and perilesional psoriatic skin from 11 male pa...
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Serum ferritin and vitamin D levels should be evaluated in patients with diffuse hair loss prior to treatment.
Conclusions: The results obtained from this study reveal that serum ferritin and 25-hydroxyvitamin D levels are generally low in patients complaining of hair loss. Therefore, serum ferritin and vitamin D levels should be evaluated and supplemented prior to treatment in all patients complaining of diffuse hair loss. PMID: 32792884 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Effects of anxiety and depression symptoms on oxidative stress in patients with alopecia areata.
Authors: Cakirca G, Manav V, Celik H, Saracoglu G, Yetkin EN Abstract Introduction: Increased oxidative stress (OXS) and a high prevalence of psychiatric disorders are seen in alopecia areata (AA). However, OXS and psychiatric disorders have been studied separately in AA patients. Aim: To determine the effects of anxiety and depression symptoms on OXS in AA patients. Material and methods: The anxiety and depression levels of 33 AA patients and 33 normal controls (NC) were determined using the Hospital Anxiety and Depression Scale. The oxidative stress index (OSI) was calculated by measuring serum total anti...
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Management of psoriatic patients in biologic treatment associated with infectious comorbidities.
Conclusions: Here we report the state of art regarding management of psoriatic patients with these co-morbidities suggesting a specific screening and management for infectious diseases in patients with moderate to severe plaque psoriasis. PMID: 32792886 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Evaluation of microvessel density with CD31 and CD105 in patients with psoriasis under methotrexate and acitretin therapy.
Conclusions: CD31 and CD105 dyes indicate the effects of therapies on vascular proliferation and may be indicators that can be used in daily routine and follow-up studies for psoriasis. PMID: 32792887 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Long-term safety and efficacy of adalimumab in psoriasis: a multicentric study focused on infections (connecting study).
Conclusions: Adalimumab is effective and safe in patients affected by these important infections. PMID: 32792888 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Maculopapular rash in COVID-19 patient treated with lopinavir/ritonavir.
Authors: Mazan P, Lesiak A, Skibiñska M, Kamerys J, Czajkowski R, Owczarek W, Narbutt J PMID: 32792889 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

34 years' duration of poikilodermatous lesion.
Authors: Liu C, Tan C PMID: 32792890 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Efficacy of long-term treatment with omalizumab in a food and inhalant allergy patient.
Authors: Nucera E, Chini R, Buonomo A, Centrone M, Aruanno A, Schiavino D PMID: 32792891 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

The complexity of clear cell acanthoma diagnosis based on the literature review.
Authors: Pogorzelska-Antkowiak A, Bergler-Czop B, Antkowiak U PMID: 32792892 [PubMed] (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - August 16, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research