The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications
Postepy Dermatol Alergol. 2023 Dec;40(6):716-724. doi: 10.5114/ada.2023.133955. Epub 2024 Jan 8.ABSTRACTAzelaic acid (AZA) is a naturally occurring saturated dicarboxylic acid whose topical application has found multiple uses in dermatology. Its anti-inflammatory, antioxidant and antimicrobial properties against Propionibacterium acne are currently used in the treatment of various types of acne such as rosacea and acne vulgaris. AZA is an inhibitor of tyrosinase, mitochondrial respiratory chain enzymes and DNA synthesis, and is a scavenger of harmful free radicals and inhibits the production of reactive oxygen species by n...
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Natalia Sauer Ma łgorzata Oślizło Marta Brzostek Julianna Wolska Katarzyna Lubaszka Katarzyna Kar łowicz-Bodalska Source Type: research

Selected hormone levels and lipid abnormalities in patients with < em > acne vulgaris < /em >
CONCLUSIONS: Our study demonstrates, that hormonal and lipid imbalance could be linked to acne vulgaris formation. Evaluation of hormonal and lipid abnormalities could help in treatment decisions and could affect the occurrence of complications and the course of acne.PMID:38282870 | PMC:PMC10809835 | DOI:10.5114/ada.2023.133457 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Weronika Szybiak Michalina Jarzemska Micha ł Kowalczyk Anna Sadowska-Przytocka Barbara Wi êckowska Ryszard Żaba Katarzyna Lacka Source Type: research

Diagnostic accuracy of peripheral lung function measurements in paediatric asthma control assessment: a pilot study
CONCLUSIONS: LCI, Sacin and Fres had the highest discriminative capacity for distinguishing children with controlled and uncontrolled asthma among all evaluated peripheral airways measures. Discrepancies in the performance (i.e. sensitivity and specificity) of each parameter suggest that a combination may be most effective in determining asthma control status.PMID:38282871 | PMC:PMC10809824 | DOI:10.5114/ada.2023.133831 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Maria Wawszczak Marek Kulus Joanna Peradzy ńska Source Type: research

Dermoscopy and reflectance confocal microscopy of metastatic Crohn's disease
Postepy Dermatol Alergol. 2023 Dec;40(6):824-826. doi: 10.5114/ada.2023.133589. Epub 2024 Jan 8.NO ABSTRACTPMID:38282872 | PMC:PMC10809822 | DOI:10.5114/ada.2023.133589 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Kinga Ko łcz El żbieta Ostańska Ewa Kaznowska Magdalena Żychowska Source Type: research

Predictors of excessive short-acting β < sub > 2 < /sub > -agonist use and asthma exacerbations: a retrospective analysis of a Polish prescription database
CONCLUSIONS: Excessive SABA use is highly prevalent in asthma management, is associated with lack of prescriptions for inhaled corticosteroids, and substantially increases the exacerbation risk.PMID:38282873 | PMC:PMC10809829 | DOI:10.5114/ada.2023.133454 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Maciej Kupczyk Wojciech Barg Gra żyna Bochenek Grzegorz Bro żek Piotr D Browiecki Dorota Brzostek Andrzej D Browski Rafa ł Dobek Rados ław Gawlik Aleksandra Kucharczyk Izabela Kupry ś-Lipińska Agnieszka Mastalerz-Migas Marek L Kowalski Source Type: research

Serum sRAGE levels in children with atopic dermatitis: a prospective study
CONCLUSIONS: To our knowledge, this is the first study investigating the association of sRAGE levels with AD and disease severity in childhood. Serum sRAGE levels are decreased in AD but not correlated with disease severity. sRAGE levels may be important in the AD disease process.PMID:38282874 | PMC:PMC10809839 | DOI:10.5114/ada.2023.133585 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Hatice Eke-Gungor Bilal Sagiroglu Zehra Nur Can-Coskun Derya Kocer Çiğdem Karakukcu Source Type: research

The relationship between lipid parameters and the course of allergic rhinitis in children
CONCLUSIONS: Children with AR are as likely to demonstrate dyslipidaemia as the general population. However, the presence of lipid abnormalities in this group may increase the likelihood of sensitization to perennial allergens.PMID:38282875 | PMC:PMC10809827 | DOI:10.5114/ada.2023.133586 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Agnieszka Kowalczyk Aneta Krogulska Source Type: research

Linear IgA dermatosis secondary to treatment with piperacillin-tazobactam in a nonagenarian patient
Postepy Dermatol Alergol. 2023 Dec;40(6):814-816. doi: 10.5114/ada.2023.133817. Epub 2024 Jan 8.NO ABSTRACTPMID:38282876 | PMC:PMC10809834 | DOI:10.5114/ada.2023.133817 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Vanesa Garc ía-Paz Carolina G ómez-Farińas Soledad S ánchez-Sánchez Andrea Otero-Alonso Clara Carballas-V ázquez Leticia Vila-Sexto Source Type: research

Relationship between body mass index < em > z < /em > -score and acne severity in adolescents: a prospective analysis
CONCLUSIONS: The findings suggest that higher BMI z-scores are linked to increased acne severity. These results emphasize the importance of addressing weight-related risk factors for the prevention and treatment of acne vulgaris. The early detection and management of weight-related conditions can play a crucial role in improving the overall well-being of individuals with acne, considering its negative impact on mental health and social functioning.PMID:38282877 | PMC:PMC10809838 | DOI:10.5114/ada.2023.133468 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Bahar Öztelcan Gündüz Hatice Ata ş Source Type: research

Efficacy and safety of upadacitinib for the treatment of moderate-to-severe atopic dermatitis: a systematic review and meta-analysis
CONCLUSIONS: This meta-analysis demonstrated that upadacitinib is a safe and effective treatment for moderate-to-severe AD. Further long-term trials are required for confirmation.PMID:38282878 | PMC:PMC10809830 | DOI:10.5114/ada.2023.133820 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Yuanjie Huang Limin Cai Xuerui Wu Chen Chen Source Type: research

Transformation of recurrent hidradenoma into a metastatic hidradenocarcinoma in a 31-year old female patient
Postepy Dermatol Alergol. 2023 Dec;40(6):820-823. doi: 10.5114/ada.2023.133588. Epub 2024 Jan 8.NO ABSTRACTPMID:38282879 | PMC:PMC10809825 | DOI:10.5114/ada.2023.133588 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Zoran Terzi ć Marinko Paunovic Ana Popovic Filip Vukmirovic Milo š Bojić Source Type: research

Observation of the clinical features of dupilumab-associated facial erythema
CONCLUSIONS: Although the mechanism of DFR is still unclear, symptomatic treatment is partially effective, and medication discontinuation and switching to Janus kinase inhibitors are acceptable for some patients.PMID:38282880 | PMC:PMC10809832 | DOI:10.5114/ada.2023.132260 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Hao Wu Weiming Zhang Zhongxiao Wu Yanna Shen Li Zhang Mouzhe Yang Yougang Ren Feng Mao Source Type: research

Allergy and immunology diffusion via social media: performance of video and audio contents on Instagram
Postepy Dermatol Alergol. 2023 Dec;40(6):817-819. doi: 10.5114/ada.2023.133607. Epub 2024 Nov 8.NO ABSTRACTPMID:38282881 | PMC:PMC10809833 | DOI:10.5114/ada.2023.133607 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Marco Cinquantasei Marcello Albanesi Source Type: research

Skin biophysical parameters and serum dermokine levels in airline pilots: a comparative study with office workers
CONCLUSIONS: We found a significant link between the profession of an airline pilot and changes in skin biophysical parameters. Further research into the interplay between serum DMKN levels and the risk of MM in APs is warranted.PMID:38282882 | PMC:PMC10809828 | DOI:10.5114/ada.2023.132262 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Piercarlo Minoretti Andr és S Santiago Sáez Ángel F García Martín Miryam Lia ńo Riera Manuel G ómez Serrano Enzo Emanuele Source Type: research

Prevalence of major food allergens in skincare products for atopic dermatitis
CONCLUSIONS: Our analysis revealed that major food allergens are prevalent in skincare products for eczema. Applying skincare products containing food derivatives on affected and inflamed skin can promote percutaneous sensitisation. Therefore, clinicians and patients with atopic dermatitis must be careful of products used for treating eczema that may contain derivatives of a major food allergen.PMID:38282883 | PMC:PMC10809837 | DOI:10.5114/ada.2023.133819 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - January 29, 2024 Category: Dermatology Authors: Klaudia Ryczaj Magdalena Chojnowska-W ójtowicz Karolina Dumycz Wojciech Feleszko Marek Kulus Source Type: research