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Aryl hydrocarbon receptor role in chronic inflammatory skin diseases: a narrative review
In conclusion, the AHR is a pivotal player in dermatology, with a multifaceted role in skin physiology and pathology. Understanding the intricacies of AHR signalling in the skin offers promising avenues for the development of novel therapies and preventive strategies for various dermatological conditions. Further research is warranted to elucidate the full scope of AHR's contributions to dermatology and its potential as a therapeutic target.PMID:38533374 | PMC:PMC10962376 | DOI:10.5114/ada.2023.135617 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Micha ł Dec Hubert Arasiewicz Source Type: research

Comparative efficacy of combined antihistamine and montelukast therapy in adult patients with atopic dermatitis
CONCLUSIONS: Comparison of data presenting the therapy outcomes in two groups showed that administration of the combined therapy was significantly more effective compared to the antihistamine monotherapy. The results revealed considerable efficacy of the combined therapy reinforced by the use of cysteinyl leukotriene receptor antagonist, montelukast.PMID:38533375 | PMC:PMC10962370 | DOI:10.5114/ada.2023.135759 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Kristina R Jamalyan Helen G Azaryan Source Type: research

Long-term efficacy, safety, and drug survival of secukinumab in patients with psoriasis in Turkey: a retrospective analysis of real-world experience
CONCLUSIONS: Close monitoring may improve SEC survival in psoriasis patients who require dose escalation and concomitant drugs.PMID:38533357 | PMC:PMC10962371 | DOI:10.5114/ada.2023.135757 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Fatma Elif Y ıldırım Fatma Asl ı Hapa Source Type: research

Effect of total astragalosides on diabetic non-healing wound by regulating immune microenvironment
CONCLUSIONS: AST can regulate the immune microenvironment of DNHW, improve α-SMA and COL-1, and accelerate the wound healing of DNHW.PMID:38533358 | PMC:PMC10962366 | DOI:10.5114/ada.2024.135989 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Weijing Fan Huimin Lu Xin Yuan Kun Zhao Guobin Liu Source Type: research

Vacuum sealing drainage technique combined with carbon nanomaterial dressings applied in the treatment of skin wounds
CONCLUSIONS: Results of this work yielded a novel therapeutic option for clinical practice, enhancing treatment outcomes and rehabilitation processes for LT patients.PMID:38533359 | PMC:PMC10962379 | DOI:10.5114/ada.2024.136036 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Yan Li Guiqiu Dong Yun Xie Jie Wang Source Type: research

Clinical relevance of cluster analysis in phenotyping allergic rhinitis in the paediatric population of the Kuyavian-Pomeranian voivodeship, Poland
CONCLUSIONS: Children with AR from the Kuyavian-Pomeranian voivodeship differing in the course of AR, the frequency of coexistence of asthma, and occurrence of lipid parameter abnormalities.PMID:38533360 | PMC:PMC10962368 | DOI:10.5114/ada.2023.135676 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Agnieszka Kowalczyk Aneta Krogulska Source Type: research

Effects of secukinumab combined with tretinoin on metabolism, liver enzymes, and inflammatory factors in patients with moderate to severe psoriasis vulgaris
CONCLUSIONS: Secukinumab combined with tretinoin is more effective in MSP vulgaris, which can visibly reduce inflammatory response without affecting glucose and lipid metabolism and liver function.PMID:38533361 | PMC:PMC10962373 | DOI:10.5114/ada.2023.135605 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Yong Chen Mei Yi Xiaoyan Pang Mengfei Du Haizhou Chen Zhenshu Li Source Type: research

Comparison of the efficacy of Hydroquinone cream versus Hydroquinone cream plus Danggui Shaoyao powder in the treatment of melasma
CONCLUSIONS: Oral DSP for 12 weeks along with hydroquinone cream can significantly reduce the MASI score of melasma patients and increase the patients' recovery and satisfaction.PMID:38533362 | PMC:PMC10962367 | DOI:10.5114/ada.2023.135613 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Yuan-Yuan Cheng Rui-Rui Peng Hao Luo Wei Zhao Source Type: research

Systematic review and network meta-analysis of the risk of Herpes zoster with biological therapies and selective Janus kinase-1 inhibitors in atopic dermatitis
CONCLUSIONS: JAK-1 inhibitors are associated with a significantly higher incidence of HZ compared to dupilumab and placebo. Our results suggest that recombinant HZ vaccination should be highly considered for all adult patients prior to starting oral JAK-1 inhibitors.PMID:38533363 | PMC:PMC10962383 | DOI:10.5114/ada.2023.135764 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Daud Manzar Nikhil Nair Emmanuel Suntres Myanca Rodrigues Mohannad Abu-Hilal Source Type: research

Nanofiber-based wound dressing in wound healing of elderly patients
CONCLUSIONS: The use of nanofiber dressings is an effective means to promote wound healing in elderly patients, which is worthy of application in practical care.PMID:38533364 | PMC:PMC10962374 | DOI:10.5114/ada.2024.136034 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Anqi Li Zhenqi Jing Yunhao Liu Youxin Wang Source Type: research

Does the effectiveness of biological medications in the treatment for psoriasis depend on the moment of starting therapy? A preliminary study
CONCLUSIONS: Our understanding of the effectiveness of the treatments depending on the time of the year combined with the type of biologics used, may further improve results of the therapy.PMID:38533365 | PMC:PMC10962378 | DOI:10.5114/ada.2024.135917 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Micha ł Niedźwiedź Marcin Noweta Joanna Narbutt Witold Owczarek Magdalena Ci ążyńska Agnieszka Czerwi ńska Janusz Krzy ścin Aleksandra Lesiak Ma łgorzata Skibińska Source Type: research

Clinicopathologic assessment of secondary syphilis avoids misdiagnosis: results of comprehensive evaluation of 114 cases
CONCLUSIONS: In this study plasma cells from superficial and deep perivascular distribution to nodular infiltration were a crucial clue for diagnosis of secondary syphilis.PMID:38533366 | PMC:PMC10962382 | DOI:10.5114/ada.2023.135755 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Wei Zhao Hao Luo Mingyuan Xu Lin Zhu Rui-Rui Peng Haikong Lu Tengfei Qi Juan Wu Yeqiang Liu Pingyu Zhou Source Type: research

Co-occurrence of otitis media with effusion and another environment-dependent disease (selected allergic conditions)
CONCLUSIONS: OME significantly more often co-exists with other conditions, particularly allergic rhinitis.PMID:38533367 | PMC:PMC10962365 | DOI:10.5114/ada.2023.135602 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Oksana Wojas Edyta Krzych-Fa łta Konrad Furma ńczyk Diana Dziewa-Dawidczyk Boles ław Samoliński Piotr Samel-Kowalik Source Type: research

Levels of serum inflammatory cytokines and their correlations with disease severity in patients with chronic spontaneous urticaria
CONCLUSIONS: IL-4, IL-17, and IL-31 showed the strongest correlation with the severity of CSU, which may be attributed to their involvement in immune, inflammatory, and pruritic reactions, exacerbating the disease condition.PMID:38533368 | PMC:PMC10962375 | DOI:10.5114/ada.2024.135922 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Wenming Zeng Jining Xia Qiming Zeng Source Type: research

Successful treatment of childhood lichen planus with upadacitinib
Postepy Dermatol Alergol. 2024 Feb;41(1):139-141. doi: 10.5114/ada.2023.135616. Epub 2024 Feb 28.NO ABSTRACTPMID:38533369 | PMC:PMC10962377 | DOI:10.5114/ada.2023.135616 (Source: Advances in Dermatology and Allergology)
Source: Advances in Dermatology and Allergology - March 27, 2024 Category: Dermatology Authors: Fangzhou Yu Weizhi Wu Shengli Chen Baoqi Yang Source Type: research