Corynebacterium pseudodiphtheriticum as a pathogen in bacterial co-infection in COVID-19 patients with mechanical ventilation
We report three cases of VAC probably due to Corynebacterium pseudodiphtheriticum in COVID-19 patients. If purulent lower respiratory specimens showed coryneform predominantly via Gram staining, empirical therapy should be started. Furthermore, species identification and drug susceptibility testing should be performed.PMID:34470958 | DOI:10.7883/yoken.JJID.2021.481 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Yoshihiko Ogawa Hiroyuki Ote Tatsuya Arai Ryo Kazama Kazuhide Kimura Toshihiko Nagata Junji Kumasawa Michihiko Kohno Hisakazu Kohata Koji Nishida Iwao Gohma Kei Kasahara Source Type: research

Oral antibiotic transition in patients with bacteremia with a urinary source due to extended-spectrum β-lactamase-producing Escherichia coli
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2020.1084. Online ahead of print.ABSTRACTTransitioning from intravenous to oral antibiotic therapy for Escherichia coli bacteremia could reduce the length of hospital stay and drug costs without compromising efficacy. Despite the expansion of extended-spectrum β-lactamase (ESBL)-producing E. coli, only limited data are available regarding the effectiveness of switching to oral antibiotic therapy in patients with bacteremia caused by this organism. To compare clinical outcomes between oral transition therapy and intravenous therapy in patients with bacteremia due t...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Taro Noguchi Koh Shinohara Yasuhiro Tsuchido Satomi Yukawa Masaki Yamamoto Yasufumi Matsumura Michiko Hayashi Yutaka Yamada Akihiko Hayashi Tsunehiro Shimizu Miki Nagao Source Type: research

Detection of quaranjavirus-like sequences from Haemaphysalis hystricis ticks collected in Japan
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.129. Online ahead of print.ABSTRACTViruses belonging to the genus Quaranjavirus in the family Orthomyxoviridae are known as argasid tick-borne viruses. Some viruses in this genus or an unassigned quaranjavirus-like virus have the ability to infect humans although little is known about their pathogenicity. During the surveillance of tick-borne viruses in ixodid ticks in Ehime Prefecture, Japan, novel quaranjavirus-like sequences were detected in three pooled samples of Haemaphysalis histricis nymphs. Phylogenetic analysis revealed that the detected viruses formed a...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Daisuke Kobayashi Ryusei Kuwata Toshiya Kimura Astri Nur Faizah Yukiko Higa Toshihiko Hayashi Kyoko Sawabe Haruhiko Isawa Source Type: research

Time to resolution of infection in COVID-19 patients: the experience of a tertiary medical center in Israel
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.215. Online ahead of print.ABSTRACTWith the coronavirus disease spreading, reports indicated that young patients are usually asymptomatic with a short convalescence period. The current study compares the time to resolution of infection in symptomatic versus asymptomatic patients. Seventy- six patients aged 44.4±23.3 years were admitted to the COVID-19 Unit during the study period. Data was collected from patients' records. Throat and nasal swabs for the RT-PCR COVID-19 were collected. Time to resolution of infection was defined as the number of days from th...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Emily Lubart Gilad Gal Eliyahu H Mizrahi Ahuva Tzabary Ehuda Baumohl Erica Pinco Zuhdi Idkiedek Eisa Haj Ali Maya Berger Galina Goltsman Source Type: research

Transmission Risk of SARS-CoV-2 Before and After Symptom Onset of the Infector
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.230. Online ahead of print.ABSTRACTAn outbreak of COVID-19 occurred in Ueda City, Nagano prefecture, Japan with a population of 150,000. Because the residents were a population naïve to COVID-19 and many of them had only one chance of exposure, careful epidemiological investigation could reveal attack rates among close contacts on the specific date of exposure. We identified 89 cases and 328 close contacts. Among the close contacts, 114 had only one chance of exposure to their 20 index cases. During the follow-up period, 17 of them tested positive for SARS-Co...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Mizue Kitahara Takuya Yamagishi Shota Tsukada Yasuhiro Sudo Tetsuya Yoshida Tomimasa Sunagawa Motoi Suzuki Source Type: research

Clinical evaluation of conventional human coronavirus infection in adults
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.250. Online ahead of print.ABSTRACTHuman coronaviruses (HCoVs) are globally distributed and cause a range of respiratory symptoms. Reports of the clinical features of HCoV infection are limited, especially in adults because of mild upper respiratory tract disease and no specific therapy available. Here we aim to evaluate the features of HCoV infection in clinical settings. Adult patients with respiratory symptoms from October 2014 to September 2019 at Nagasaki Genbaku Isahaya Hospital were enrolled. The multiplex reverse-transcription polymerase chain reaction (RT...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Kazumasa Akagi Toru Kubo Ritsuko Miyashita Akira Kondo Naomi Ehara Takahiro Takazono Noriho Sakamoto Hiroshi Mukae Kouichi Morita Kiyoyasu Fukushima Source Type: research

Respiratory syncytial virus outbreaks are predicted after the COVID-19 pandemic in Tokyo, Japan
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.312. Online ahead of print.ABSTRACTThe nonpharmaceutical interventions (NPIs) on COVID-19 can impact current and future dynamics of respiratory syncytial virus infections (RSV). In Tokyo, RSV activity declined by 97.9% (95%CI: 94.8% - 99.2%) during NPIs. A longer period of NPIs could expand susceptible populations, enhancing the potential for larger RSV outbreaks after NPIs ends.PMID:34470964 | DOI:10.7883/yoken.JJID.2021.312 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Lina Madaniyazi Xerxes Seposo Chris Fook Sheng Ng Aurelio Tobias Michiko Toizumi Hiroyuki Moriuchi Lay-Myint Yoshida Masahiro Hashizume Source Type: research

Comparison of Clinical, Demographic Features and Costs in Respiratory Syncytial Virus, Rhinovirus and Viral Co-infections in Hospitalized Children with Lower Respiratory Tract Infections
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.328. Online ahead of print.ABSTRACTViruses are the most common cause of lower respiratory tract infections (LRTIs) in children. Our study aims to shed light on co-infections by comparing with the most common single agents, Respiratory syncytial virus (RSV) and Rhinovirus (RV), in terms of epidemiological, clinical, laboratory and cost. This retrospective study included infants under the age of five, hospitalized with a diagnosis of LRTI with RSV, RV or co-infection were analyzed. The study group consisted of 199 children, RSV was detected in 116 patients (58,3%), ...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Sema Ekinci Sert Cuneyt Karagol Ali Gungor Belgin Gulhan Source Type: research

Socio- demographic correlates of HIV sero-discordance among couples in West Bengal, India; A cross sectional analysis
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.330. Online ahead of print.ABSTRACTSerodiscordant couples serves as potential source of Human Immunodeficiency Virus (HIV) transmission. Understanding demographic dynamics of serodiscordant couples plays an important role in tailoring interventions towards eliminating HIV. We conducted this cross sectional analysis in 314 Integrated Counseling and Testing Centres (ICTCs) in West Bengal, India during April 2016 to March 2020. General individuals who were detected as HIV reactive and whose spouses were also tested for HIV comprised the study population (8740 couples...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Debjit Chakraborty Suman Ganguly Falguni Debnath Subrata Biswas Malay Kumar Saha Shanta Dutta Source Type: research

Complete genome sequencing and comparative analysis of Citrobacter koseri CKNJ, a strain isolated from patient with endogenous endophthalmitis
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.334. Online ahead of print.ABSTRACTCitrobacter koseri is an opportnistic pathogen can cause a variety of diseases. Though the mortality rate of C. koseri infections is high but there is a paucity of clinical information on them. Furthermore, the genomic features of this species are poorly studied. Herein, we presented a patient with endogenous endophthalmitis secondary to septicaemia, and collected a C. koseri isolate, CKNJ, from the blood of the patient. Whole genome sequencing revealed that the CKNJ harbors no plasmid and codes for 67 putative virulence factors....
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Qiaoyan Yue Qiyue Zhang Yueqin Wang Xiaoju He Kang Ding Xiaofeng Wang Haiyan Xi Lulu Wang Yanliang Zhang Chao Wu Source Type: research

Multi-Locus Sequence Typing and Lipooligosaccharide Class Analysis of Campylobacter jejuni HS:19 Isolated in Japan
In conclusion, C. jejuni HS:19 had high clonality, regardless of its origin, over other capsule types in Japan.PMID:34470968 | DOI:10.7883/yoken.JJID.2021.341 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Satoru Akase Keiko Yokoyama Hiromi Obata Chie Monma Noriko Konishi Kaoru Hatakeyama Dai Saiki Masako Maeda Chikako Asayama Jun Suzuki Kenji Sadamasu Source Type: research

Detection, isolation and molecular characterization of Escherichia albertii in wild birds in West Japan
In conclusion, Japanese wild birds carried E. albertii at the similar levels to the reported prevalence in birds. These isolates may have a potential to cause gastroenteritis in humans.PMID:34470969 | DOI:10.7883/yoken.JJID.2021.355 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Atsushi Hinenoya Sharda Prasad Awasthi Noritomo Yasuda Keigo Nagano Jayedul Hassan Keiji Takehira Noritoshi Hatanaka Shun Saito Takashi Watabe Miki Yoshizawa Haruna Inoue Shinji Yamasaki Source Type: research

Aedes albopictus Strain and Dengue Virus Serotype in the Dengue Fever Outbreaks in Japan: Implications of Wolbachia Infection
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.376. Online ahead of print.ABSTRACTFrom August 27 to October 15, 2014, a dengue fever outbreak with 158 autochthonous cases occurred after nearly 70 years of no reports of autochthonous cases in Japan. The most competent mosquito vector for dengue virus (DENV) transmission in Japan is Aedes albopictus. Since A. albopictus is widely distributed throughout Japan, we examined the susceptibility of this species to infection by DENV and the relationship of the endosymbiont Wolbachia (wAlbA and wAlbB) with susceptibility to DENV. The A. albopictus YYG strain, collected ...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Toshinori Sasaki Meng Ling Moi Kazumi Saito Haruhiko Isawa Tomohiko Takasaki Kyoko Sawabe Source Type: research

Clinical and laboratory characteristics of childhood brucellosis in high-risk area of Western China
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.388. Online ahead of print.ABSTRACTChildhood brucellosis present various non-specific clinical symptoms, and limited laboratory data exist for clinical diagnosis. A better understanding of these clinical and laboratory characteristics can avoid clinical misdiagnosis and mistreatment. In this case-series study, a total of 78 children with confirmed diagnosis of brucellosis were evaluated retrospectively. We observed that the incidence rate was higher in the first two quarters every year. The most common symptom was fever. Osteoarticular involvement was found in 44....
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Wei Wang Zengguo Wang Kai Jia Jianyong Tang Lin Wang Source Type: research

Epidemiological and clinical characteristics of severe fever with thrombocytopenia syndrome in southern Anhui Province, 2011-2020
In this study, a retrospective analysis of 86 patients that diagnosed with SFTS from two five-year periods (2011-2015 and 2016-2020) that was performed to explore the changes in epidemiology, clinical characteristics, laboratory parameters and prognosis between those two periods. The results showed that there were significant differences in age, the proportion of farmers, geographical distribution, the incidence of multiple organ dysfunction, the decrease in thrombocyte count, and the elevations of serum AST and lipase levels between the two groups (p
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Wenjie Wang Aiping Zhang Qiongle Wu Lingling Zhu Jinsun Yang Source Type: research

Corynebacterium pseudodiphtheriticum as a pathogen in bacterial co-infection in COVID-19 patients with mechanical ventilation
We report three cases of VAC probably due to Corynebacterium pseudodiphtheriticum in COVID-19 patients. If purulent lower respiratory specimens showed coryneform predominantly via Gram staining, empirical therapy should be started. Furthermore, species identification and drug susceptibility testing should be performed.PMID:34470958 | DOI:10.7883/yoken.JJID.2021.481 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Yoshihiko Ogawa Hiroyuki Ote Tatsuya Arai Ryo Kazama Kazuhide Kimura Toshihiko Nagata Junji Kumasawa Michihiko Kohno Hisakazu Kohata Koji Nishida Iwao Gohma Kei Kasahara Source Type: research

Oral antibiotic transition in patients with bacteremia with a urinary source due to extended-spectrum β-lactamase-producing Escherichia coli
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2020.1084. Online ahead of print.ABSTRACTTransitioning from intravenous to oral antibiotic therapy for Escherichia coli bacteremia could reduce the length of hospital stay and drug costs without compromising efficacy. Despite the expansion of extended-spectrum β-lactamase (ESBL)-producing E. coli, only limited data are available regarding the effectiveness of switching to oral antibiotic therapy in patients with bacteremia caused by this organism. To compare clinical outcomes between oral transition therapy and intravenous therapy in patients with bacteremia due t...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Taro Noguchi Koh Shinohara Yasuhiro Tsuchido Satomi Yukawa Masaki Yamamoto Yasufumi Matsumura Michiko Hayashi Yutaka Yamada Akihiko Hayashi Tsunehiro Shimizu Miki Nagao Source Type: research

Detection of quaranjavirus-like sequences from Haemaphysalis hystricis ticks collected in Japan
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.129. Online ahead of print.ABSTRACTViruses belonging to the genus Quaranjavirus in the family Orthomyxoviridae are known as argasid tick-borne viruses. Some viruses in this genus or an unassigned quaranjavirus-like virus have the ability to infect humans although little is known about their pathogenicity. During the surveillance of tick-borne viruses in ixodid ticks in Ehime Prefecture, Japan, novel quaranjavirus-like sequences were detected in three pooled samples of Haemaphysalis histricis nymphs. Phylogenetic analysis revealed that the detected viruses formed a...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Daisuke Kobayashi Ryusei Kuwata Toshiya Kimura Astri Nur Faizah Yukiko Higa Toshihiko Hayashi Kyoko Sawabe Haruhiko Isawa Source Type: research

Time to resolution of infection in COVID-19 patients: the experience of a tertiary medical center in Israel
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.215. Online ahead of print.ABSTRACTWith the coronavirus disease spreading, reports indicated that young patients are usually asymptomatic with a short convalescence period. The current study compares the time to resolution of infection in symptomatic versus asymptomatic patients. Seventy- six patients aged 44.4±23.3 years were admitted to the COVID-19 Unit during the study period. Data was collected from patients' records. Throat and nasal swabs for the RT-PCR COVID-19 were collected. Time to resolution of infection was defined as the number of days from th...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Emily Lubart Gilad Gal Eliyahu H Mizrahi Ahuva Tzabary Ehuda Baumohl Erica Pinco Zuhdi Idkiedek Eisa Haj Ali Maya Berger Galina Goltsman Source Type: research

Transmission Risk of SARS-CoV-2 Before and After Symptom Onset of the Infector
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.230. Online ahead of print.ABSTRACTAn outbreak of COVID-19 occurred in Ueda City, Nagano prefecture, Japan with a population of 150,000. Because the residents were a population naïve to COVID-19 and many of them had only one chance of exposure, careful epidemiological investigation could reveal attack rates among close contacts on the specific date of exposure. We identified 89 cases and 328 close contacts. Among the close contacts, 114 had only one chance of exposure to their 20 index cases. During the follow-up period, 17 of them tested positive for SARS-Co...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Mizue Kitahara Takuya Yamagishi Shota Tsukada Yasuhiro Sudo Tetsuya Yoshida Tomimasa Sunagawa Motoi Suzuki Source Type: research

Clinical evaluation of conventional human coronavirus infection in adults
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.250. Online ahead of print.ABSTRACTHuman coronaviruses (HCoVs) are globally distributed and cause a range of respiratory symptoms. Reports of the clinical features of HCoV infection are limited, especially in adults because of mild upper respiratory tract disease and no specific therapy available. Here we aim to evaluate the features of HCoV infection in clinical settings. Adult patients with respiratory symptoms from October 2014 to September 2019 at Nagasaki Genbaku Isahaya Hospital were enrolled. The multiplex reverse-transcription polymerase chain reaction (RT...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Kazumasa Akagi Toru Kubo Ritsuko Miyashita Akira Kondo Naomi Ehara Takahiro Takazono Noriho Sakamoto Hiroshi Mukae Kouichi Morita Kiyoyasu Fukushima Source Type: research

Respiratory syncytial virus outbreaks are predicted after the COVID-19 pandemic in Tokyo, Japan
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.312. Online ahead of print.ABSTRACTThe nonpharmaceutical interventions (NPIs) on COVID-19 can impact current and future dynamics of respiratory syncytial virus infections (RSV). In Tokyo, RSV activity declined by 97.9% (95%CI: 94.8% - 99.2%) during NPIs. A longer period of NPIs could expand susceptible populations, enhancing the potential for larger RSV outbreaks after NPIs ends.PMID:34470964 | DOI:10.7883/yoken.JJID.2021.312 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Lina Madaniyazi Xerxes Seposo Chris Fook Sheng Ng Aurelio Tobias Michiko Toizumi Hiroyuki Moriuchi Lay-Myint Yoshida Masahiro Hashizume Source Type: research

Comparison of Clinical, Demographic Features and Costs in Respiratory Syncytial Virus, Rhinovirus and Viral Co-infections in Hospitalized Children with Lower Respiratory Tract Infections
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.328. Online ahead of print.ABSTRACTViruses are the most common cause of lower respiratory tract infections (LRTIs) in children. Our study aims to shed light on co-infections by comparing with the most common single agents, Respiratory syncytial virus (RSV) and Rhinovirus (RV), in terms of epidemiological, clinical, laboratory and cost. This retrospective study included infants under the age of five, hospitalized with a diagnosis of LRTI with RSV, RV or co-infection were analyzed. The study group consisted of 199 children, RSV was detected in 116 patients (58,3%), ...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Sema Ekinci Sert Cuneyt Karagol Ali Gungor Belgin Gulhan Source Type: research

Socio- demographic correlates of HIV sero-discordance among couples in West Bengal, India; A cross sectional analysis
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.330. Online ahead of print.ABSTRACTSerodiscordant couples serves as potential source of Human Immunodeficiency Virus (HIV) transmission. Understanding demographic dynamics of serodiscordant couples plays an important role in tailoring interventions towards eliminating HIV. We conducted this cross sectional analysis in 314 Integrated Counseling and Testing Centres (ICTCs) in West Bengal, India during April 2016 to March 2020. General individuals who were detected as HIV reactive and whose spouses were also tested for HIV comprised the study population (8740 couples...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Debjit Chakraborty Suman Ganguly Falguni Debnath Subrata Biswas Malay Kumar Saha Shanta Dutta Source Type: research

Complete genome sequencing and comparative analysis of Citrobacter koseri CKNJ, a strain isolated from patient with endogenous endophthalmitis
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.334. Online ahead of print.ABSTRACTCitrobacter koseri is an opportnistic pathogen can cause a variety of diseases. Though the mortality rate of C. koseri infections is high but there is a paucity of clinical information on them. Furthermore, the genomic features of this species are poorly studied. Herein, we presented a patient with endogenous endophthalmitis secondary to septicaemia, and collected a C. koseri isolate, CKNJ, from the blood of the patient. Whole genome sequencing revealed that the CKNJ harbors no plasmid and codes for 67 putative virulence factors....
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Qiaoyan Yue Qiyue Zhang Yueqin Wang Xiaoju He Kang Ding Xiaofeng Wang Haiyan Xi Lulu Wang Yanliang Zhang Chao Wu Source Type: research

Multi-Locus Sequence Typing and Lipooligosaccharide Class Analysis of Campylobacter jejuni HS:19 Isolated in Japan
In conclusion, C. jejuni HS:19 had high clonality, regardless of its origin, over other capsule types in Japan.PMID:34470968 | DOI:10.7883/yoken.JJID.2021.341 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Satoru Akase Keiko Yokoyama Hiromi Obata Chie Monma Noriko Konishi Kaoru Hatakeyama Dai Saiki Masako Maeda Chikako Asayama Jun Suzuki Kenji Sadamasu Source Type: research

Detection, isolation and molecular characterization of Escherichia albertii in wild birds in West Japan
In conclusion, Japanese wild birds carried E. albertii at the similar levels to the reported prevalence in birds. These isolates may have a potential to cause gastroenteritis in humans.PMID:34470969 | DOI:10.7883/yoken.JJID.2021.355 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Atsushi Hinenoya Sharda Prasad Awasthi Noritomo Yasuda Keigo Nagano Jayedul Hassan Keiji Takehira Noritoshi Hatanaka Shun Saito Takashi Watabe Miki Yoshizawa Haruna Inoue Shinji Yamasaki Source Type: research

Aedes albopictus Strain and Dengue Virus Serotype in the Dengue Fever Outbreaks in Japan: Implications of Wolbachia Infection
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.376. Online ahead of print.ABSTRACTFrom August 27 to October 15, 2014, a dengue fever outbreak with 158 autochthonous cases occurred after nearly 70 years of no reports of autochthonous cases in Japan. The most competent mosquito vector for dengue virus (DENV) transmission in Japan is Aedes albopictus. Since A. albopictus is widely distributed throughout Japan, we examined the susceptibility of this species to infection by DENV and the relationship of the endosymbiont Wolbachia (wAlbA and wAlbB) with susceptibility to DENV. The A. albopictus YYG strain, collected ...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Toshinori Sasaki Meng Ling Moi Kazumi Saito Haruhiko Isawa Tomohiko Takasaki Kyoko Sawabe Source Type: research

Clinical and laboratory characteristics of childhood brucellosis in high-risk area of Western China
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.388. Online ahead of print.ABSTRACTChildhood brucellosis present various non-specific clinical symptoms, and limited laboratory data exist for clinical diagnosis. A better understanding of these clinical and laboratory characteristics can avoid clinical misdiagnosis and mistreatment. In this case-series study, a total of 78 children with confirmed diagnosis of brucellosis were evaluated retrospectively. We observed that the incidence rate was higher in the first two quarters every year. The most common symptom was fever. Osteoarticular involvement was found in 44....
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Wei Wang Zengguo Wang Kai Jia Jianyong Tang Lin Wang Source Type: research

Epidemiological and clinical characteristics of severe fever with thrombocytopenia syndrome in southern Anhui Province, 2011-2020
In this study, a retrospective analysis of 86 patients that diagnosed with SFTS from two five-year periods (2011-2015 and 2016-2020) that was performed to explore the changes in epidemiology, clinical characteristics, laboratory parameters and prognosis between those two periods. The results showed that there were significant differences in age, the proportion of farmers, geographical distribution, the incidence of multiple organ dysfunction, the decrease in thrombocyte count, and the elevations of serum AST and lipase levels between the two groups (p
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Wenjie Wang Aiping Zhang Qiongle Wu Lingling Zhu Jinsun Yang Source Type: research

Corynebacterium pseudodiphtheriticum as a pathogen in bacterial co-infection in COVID-19 patients with mechanical ventilation
We report three cases of VAC probably due to Corynebacterium pseudodiphtheriticum in COVID-19 patients. If purulent lower respiratory specimens showed coryneform predominantly via Gram staining, empirical therapy should be started. Furthermore, species identification and drug susceptibility testing should be performed.PMID:34470958 | DOI:10.7883/yoken.JJID.2021.481 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Yoshihiko Ogawa Hiroyuki Ote Tatsuya Arai Ryo Kazama Kazuhide Kimura Toshihiko Nagata Junji Kumasawa Michihiko Kohno Hisakazu Kohata Koji Nishida Iwao Gohma Kei Kasahara Source Type: research

Oral antibiotic transition in patients with bacteremia with a urinary source due to extended-spectrum β-lactamase-producing Escherichia coli
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2020.1084. Online ahead of print.ABSTRACTTransitioning from intravenous to oral antibiotic therapy for Escherichia coli bacteremia could reduce the length of hospital stay and drug costs without compromising efficacy. Despite the expansion of extended-spectrum β-lactamase (ESBL)-producing E. coli, only limited data are available regarding the effectiveness of switching to oral antibiotic therapy in patients with bacteremia caused by this organism. To compare clinical outcomes between oral transition therapy and intravenous therapy in patients with bacteremia due t...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Taro Noguchi Koh Shinohara Yasuhiro Tsuchido Satomi Yukawa Masaki Yamamoto Yasufumi Matsumura Michiko Hayashi Yutaka Yamada Akihiko Hayashi Tsunehiro Shimizu Miki Nagao Source Type: research

Detection of quaranjavirus-like sequences from Haemaphysalis hystricis ticks collected in Japan
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.129. Online ahead of print.ABSTRACTViruses belonging to the genus Quaranjavirus in the family Orthomyxoviridae are known as argasid tick-borne viruses. Some viruses in this genus or an unassigned quaranjavirus-like virus have the ability to infect humans although little is known about their pathogenicity. During the surveillance of tick-borne viruses in ixodid ticks in Ehime Prefecture, Japan, novel quaranjavirus-like sequences were detected in three pooled samples of Haemaphysalis histricis nymphs. Phylogenetic analysis revealed that the detected viruses formed a...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Daisuke Kobayashi Ryusei Kuwata Toshiya Kimura Astri Nur Faizah Yukiko Higa Toshihiko Hayashi Kyoko Sawabe Haruhiko Isawa Source Type: research

Time to resolution of infection in COVID-19 patients: the experience of a tertiary medical center in Israel
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.215. Online ahead of print.ABSTRACTWith the coronavirus disease spreading, reports indicated that young patients are usually asymptomatic with a short convalescence period. The current study compares the time to resolution of infection in symptomatic versus asymptomatic patients. Seventy- six patients aged 44.4±23.3 years were admitted to the COVID-19 Unit during the study period. Data was collected from patients' records. Throat and nasal swabs for the RT-PCR COVID-19 were collected. Time to resolution of infection was defined as the number of days from th...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Emily Lubart Gilad Gal Eliyahu H Mizrahi Ahuva Tzabary Ehuda Baumohl Erica Pinco Zuhdi Idkiedek Eisa Haj Ali Maya Berger Galina Goltsman Source Type: research

Transmission Risk of SARS-CoV-2 Before and After Symptom Onset of the Infector
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.230. Online ahead of print.ABSTRACTAn outbreak of COVID-19 occurred in Ueda City, Nagano prefecture, Japan with a population of 150,000. Because the residents were a population naïve to COVID-19 and many of them had only one chance of exposure, careful epidemiological investigation could reveal attack rates among close contacts on the specific date of exposure. We identified 89 cases and 328 close contacts. Among the close contacts, 114 had only one chance of exposure to their 20 index cases. During the follow-up period, 17 of them tested positive for SARS-Co...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Mizue Kitahara Takuya Yamagishi Shota Tsukada Yasuhiro Sudo Tetsuya Yoshida Tomimasa Sunagawa Motoi Suzuki Source Type: research

Clinical evaluation of conventional human coronavirus infection in adults
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.250. Online ahead of print.ABSTRACTHuman coronaviruses (HCoVs) are globally distributed and cause a range of respiratory symptoms. Reports of the clinical features of HCoV infection are limited, especially in adults because of mild upper respiratory tract disease and no specific therapy available. Here we aim to evaluate the features of HCoV infection in clinical settings. Adult patients with respiratory symptoms from October 2014 to September 2019 at Nagasaki Genbaku Isahaya Hospital were enrolled. The multiplex reverse-transcription polymerase chain reaction (RT...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Kazumasa Akagi Toru Kubo Ritsuko Miyashita Akira Kondo Naomi Ehara Takahiro Takazono Noriho Sakamoto Hiroshi Mukae Kouichi Morita Kiyoyasu Fukushima Source Type: research

Respiratory syncytial virus outbreaks are predicted after the COVID-19 pandemic in Tokyo, Japan
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.312. Online ahead of print.ABSTRACTThe nonpharmaceutical interventions (NPIs) on COVID-19 can impact current and future dynamics of respiratory syncytial virus infections (RSV). In Tokyo, RSV activity declined by 97.9% (95%CI: 94.8% - 99.2%) during NPIs. A longer period of NPIs could expand susceptible populations, enhancing the potential for larger RSV outbreaks after NPIs ends.PMID:34470964 | DOI:10.7883/yoken.JJID.2021.312 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Lina Madaniyazi Xerxes Seposo Chris Fook Sheng Ng Aurelio Tobias Michiko Toizumi Hiroyuki Moriuchi Lay-Myint Yoshida Masahiro Hashizume Source Type: research

Comparison of Clinical, Demographic Features and Costs in Respiratory Syncytial Virus, Rhinovirus and Viral Co-infections in Hospitalized Children with Lower Respiratory Tract Infections
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.328. Online ahead of print.ABSTRACTViruses are the most common cause of lower respiratory tract infections (LRTIs) in children. Our study aims to shed light on co-infections by comparing with the most common single agents, Respiratory syncytial virus (RSV) and Rhinovirus (RV), in terms of epidemiological, clinical, laboratory and cost. This retrospective study included infants under the age of five, hospitalized with a diagnosis of LRTI with RSV, RV or co-infection were analyzed. The study group consisted of 199 children, RSV was detected in 116 patients (58,3%), ...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Sema Ekinci Sert Cuneyt Karagol Ali Gungor Belgin Gulhan Source Type: research

Socio- demographic correlates of HIV sero-discordance among couples in West Bengal, India; A cross sectional analysis
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.330. Online ahead of print.ABSTRACTSerodiscordant couples serves as potential source of Human Immunodeficiency Virus (HIV) transmission. Understanding demographic dynamics of serodiscordant couples plays an important role in tailoring interventions towards eliminating HIV. We conducted this cross sectional analysis in 314 Integrated Counseling and Testing Centres (ICTCs) in West Bengal, India during April 2016 to March 2020. General individuals who were detected as HIV reactive and whose spouses were also tested for HIV comprised the study population (8740 couples...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Debjit Chakraborty Suman Ganguly Falguni Debnath Subrata Biswas Malay Kumar Saha Shanta Dutta Source Type: research

Complete genome sequencing and comparative analysis of Citrobacter koseri CKNJ, a strain isolated from patient with endogenous endophthalmitis
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.334. Online ahead of print.ABSTRACTCitrobacter koseri is an opportnistic pathogen can cause a variety of diseases. Though the mortality rate of C. koseri infections is high but there is a paucity of clinical information on them. Furthermore, the genomic features of this species are poorly studied. Herein, we presented a patient with endogenous endophthalmitis secondary to septicaemia, and collected a C. koseri isolate, CKNJ, from the blood of the patient. Whole genome sequencing revealed that the CKNJ harbors no plasmid and codes for 67 putative virulence factors....
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Qiaoyan Yue Qiyue Zhang Yueqin Wang Xiaoju He Kang Ding Xiaofeng Wang Haiyan Xi Lulu Wang Yanliang Zhang Chao Wu Source Type: research

Multi-Locus Sequence Typing and Lipooligosaccharide Class Analysis of Campylobacter jejuni HS:19 Isolated in Japan
In conclusion, C. jejuni HS:19 had high clonality, regardless of its origin, over other capsule types in Japan.PMID:34470968 | DOI:10.7883/yoken.JJID.2021.341 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Satoru Akase Keiko Yokoyama Hiromi Obata Chie Monma Noriko Konishi Kaoru Hatakeyama Dai Saiki Masako Maeda Chikako Asayama Jun Suzuki Kenji Sadamasu Source Type: research

Detection, isolation and molecular characterization of Escherichia albertii in wild birds in West Japan
In conclusion, Japanese wild birds carried E. albertii at the similar levels to the reported prevalence in birds. These isolates may have a potential to cause gastroenteritis in humans.PMID:34470969 | DOI:10.7883/yoken.JJID.2021.355 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Atsushi Hinenoya Sharda Prasad Awasthi Noritomo Yasuda Keigo Nagano Jayedul Hassan Keiji Takehira Noritoshi Hatanaka Shun Saito Takashi Watabe Miki Yoshizawa Haruna Inoue Shinji Yamasaki Source Type: research

Aedes albopictus Strain and Dengue Virus Serotype in the Dengue Fever Outbreaks in Japan: Implications of Wolbachia Infection
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.376. Online ahead of print.ABSTRACTFrom August 27 to October 15, 2014, a dengue fever outbreak with 158 autochthonous cases occurred after nearly 70 years of no reports of autochthonous cases in Japan. The most competent mosquito vector for dengue virus (DENV) transmission in Japan is Aedes albopictus. Since A. albopictus is widely distributed throughout Japan, we examined the susceptibility of this species to infection by DENV and the relationship of the endosymbiont Wolbachia (wAlbA and wAlbB) with susceptibility to DENV. The A. albopictus YYG strain, collected ...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Toshinori Sasaki Meng Ling Moi Kazumi Saito Haruhiko Isawa Tomohiko Takasaki Kyoko Sawabe Source Type: research

Clinical and laboratory characteristics of childhood brucellosis in high-risk area of Western China
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.388. Online ahead of print.ABSTRACTChildhood brucellosis present various non-specific clinical symptoms, and limited laboratory data exist for clinical diagnosis. A better understanding of these clinical and laboratory characteristics can avoid clinical misdiagnosis and mistreatment. In this case-series study, a total of 78 children with confirmed diagnosis of brucellosis were evaluated retrospectively. We observed that the incidence rate was higher in the first two quarters every year. The most common symptom was fever. Osteoarticular involvement was found in 44....
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Wei Wang Zengguo Wang Kai Jia Jianyong Tang Lin Wang Source Type: research

Epidemiological and clinical characteristics of severe fever with thrombocytopenia syndrome in southern Anhui Province, 2011-2020
In this study, a retrospective analysis of 86 patients that diagnosed with SFTS from two five-year periods (2011-2015 and 2016-2020) that was performed to explore the changes in epidemiology, clinical characteristics, laboratory parameters and prognosis between those two periods. The results showed that there were significant differences in age, the proportion of farmers, geographical distribution, the incidence of multiple organ dysfunction, the decrease in thrombocyte count, and the elevations of serum AST and lipase levels between the two groups (p
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Wenjie Wang Aiping Zhang Qiongle Wu Lingling Zhu Jinsun Yang Source Type: research

Corynebacterium pseudodiphtheriticum as a pathogen in bacterial co-infection in COVID-19 patients with mechanical ventilation
We report three cases of VAC probably due to Corynebacterium pseudodiphtheriticum in COVID-19 patients. If purulent lower respiratory specimens showed coryneform predominantly via Gram staining, empirical therapy should be started. Furthermore, species identification and drug susceptibility testing should be performed.PMID:34470958 | DOI:10.7883/yoken.JJID.2021.481 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Yoshihiko Ogawa Hiroyuki Ote Tatsuya Arai Ryo Kazama Kazuhide Kimura Toshihiko Nagata Junji Kumasawa Michihiko Kohno Hisakazu Kohata Koji Nishida Iwao Gohma Kei Kasahara Source Type: research

Oral antibiotic transition in patients with bacteremia with a urinary source due to extended-spectrum β-lactamase-producing Escherichia coli
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2020.1084. Online ahead of print.ABSTRACTTransitioning from intravenous to oral antibiotic therapy for Escherichia coli bacteremia could reduce the length of hospital stay and drug costs without compromising efficacy. Despite the expansion of extended-spectrum β-lactamase (ESBL)-producing E. coli, only limited data are available regarding the effectiveness of switching to oral antibiotic therapy in patients with bacteremia caused by this organism. To compare clinical outcomes between oral transition therapy and intravenous therapy in patients with bacteremia due t...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Taro Noguchi Koh Shinohara Yasuhiro Tsuchido Satomi Yukawa Masaki Yamamoto Yasufumi Matsumura Michiko Hayashi Yutaka Yamada Akihiko Hayashi Tsunehiro Shimizu Miki Nagao Source Type: research

Detection of quaranjavirus-like sequences from Haemaphysalis hystricis ticks collected in Japan
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.129. Online ahead of print.ABSTRACTViruses belonging to the genus Quaranjavirus in the family Orthomyxoviridae are known as argasid tick-borne viruses. Some viruses in this genus or an unassigned quaranjavirus-like virus have the ability to infect humans although little is known about their pathogenicity. During the surveillance of tick-borne viruses in ixodid ticks in Ehime Prefecture, Japan, novel quaranjavirus-like sequences were detected in three pooled samples of Haemaphysalis histricis nymphs. Phylogenetic analysis revealed that the detected viruses formed a...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Daisuke Kobayashi Ryusei Kuwata Toshiya Kimura Astri Nur Faizah Yukiko Higa Toshihiko Hayashi Kyoko Sawabe Haruhiko Isawa Source Type: research

Time to resolution of infection in COVID-19 patients: the experience of a tertiary medical center in Israel
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.215. Online ahead of print.ABSTRACTWith the coronavirus disease spreading, reports indicated that young patients are usually asymptomatic with a short convalescence period. The current study compares the time to resolution of infection in symptomatic versus asymptomatic patients. Seventy- six patients aged 44.4±23.3 years were admitted to the COVID-19 Unit during the study period. Data was collected from patients' records. Throat and nasal swabs for the RT-PCR COVID-19 were collected. Time to resolution of infection was defined as the number of days from th...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Emily Lubart Gilad Gal Eliyahu H Mizrahi Ahuva Tzabary Ehuda Baumohl Erica Pinco Zuhdi Idkiedek Eisa Haj Ali Maya Berger Galina Goltsman Source Type: research

Transmission Risk of SARS-CoV-2 Before and After Symptom Onset of the Infector
Jpn J Infect Dis. 2021 Aug 31. doi: 10.7883/yoken.JJID.2021.230. Online ahead of print.ABSTRACTAn outbreak of COVID-19 occurred in Ueda City, Nagano prefecture, Japan with a population of 150,000. Because the residents were a population naïve to COVID-19 and many of them had only one chance of exposure, careful epidemiological investigation could reveal attack rates among close contacts on the specific date of exposure. We identified 89 cases and 328 close contacts. Among the close contacts, 114 had only one chance of exposure to their 20 index cases. During the follow-up period, 17 of them tested positive for SARS-Co...
Source: Japanese Journal of Infectious Diseases - September 2, 2021 Category: Infectious Diseases Authors: Mizue Kitahara Takuya Yamagishi Shota Tsukada Yasuhiro Sudo Tetsuya Yoshida Tomimasa Sunagawa Motoi Suzuki Source Type: research