Japanese Journal of Infectious Diseases This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

β-Lactam Susceptibility of Streptococcus dysgalactiae subsp. equisimilis
In this study, we attempted to detect β-lactam-non-susceptible clinical isolates of SDSE in Japan. One hundred and fifty clinical isolates of S. dysgalactiae were collected in 2018, and species identification was performed using Rapid ID Strep API. The minimum inhibitory concentrations (MIC) of six β-lactams (penicillin G, oxacillin, ceftizoxime, ceftibuten, cefoxitin, and cefaclor) were determined for 85 clinical isolates of SDSE using the agar dilution method standardized by the Clinical Laboratory Standards Institute. For the 85 isolates identified as SDSE, the MIC ranges of penicillin G, oxacillin, ceftizoxime, cefti...
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Natsumi Nakashima Wanchun Jin Jun-Ichi Wachino Shinobu Koyama Kiyoko Tamai Yoshichika Arakawa Kouji Kimura Source Type: research

The Efficacy and Safety of Nafamostat Mesylate in the Treatment of COVID-19: A Meta-Analysis
Jpn J Infect Dis. 2024 Jan 31. doi: 10.7883/yoken.JJID.2023.315. Online ahead of print.ABSTRACTNafamostat mesylate, a synthetic serine protease inhibitor, has demonstrated early antiviral activity against SARS-CoV-2 and anticoagulant properties that may be beneficial in COVID-19. We conducted a meta-analysis evaluating the efficacy and safety of nafamostat mesylate for COVID-19 treatment. PubMed, Embase, Cochrane Library, Scopus, Web of Science, medRxiv and bioRxiv were searched up to July 2023 for studies comparing outcomes between nafamostat mesylate treatment and no nafamostat mesylate treatment in COVID-19 patients. Mo...
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Mian Wei Toni Li Siyuan Liu Yushu Wang Carolyn Tran Guangyu Ao Source Type: research

Genetic comparison of human parainfluenza virus type 3 detected in respiratory samples from patients with encephalopathy and airway inflammation in Aichi Prefecture, Japan
Jpn J Infect Dis. 2024 Jan 31. doi: 10.7883/yoken.JJID.2023.265. Online ahead of print.ABSTRACTHuman parainfluenza virus type 3 (HPIV-3, Human respirovirus 3) is the second most frequently detected virus after human respiratory syncytial virus (HRSV) in lower respiratory tract infections in children. HPIV-3, like its close relative respiratory viruses, HRSV and influenza virus, may cause encephalopathy, but the relevance of HPIV-3 as a pathogenic factor in encephalopathy is unknown. We attempted to detect HPIV-1 through 4, HRSV, and human metapneumovirus (HMPV) in 136 patients with encephalitis/encephalopathy, or suspected...
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Hirokazu Adachi Hiroko Minagawa Emi Hirose Noriko Nakamura Hitomi Niimi Noriko Saito Miyabi Ito Katsuhiko Sato Yoshihiro Yasui Source Type: research

Proton pump inhibitors and risk of bloodstream infection without an identifiable source: a hospital-based case-control study
In conclusion, PPI use is associated with higher risk of BSI without an identifiable source and therefore, PPI use may increase the risk of septic morbidity secondary to bacterial translocation.PMID:38296545 | DOI:10.7883/yoken.JJID.2023.253 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Shintaro Hayashi Tomohito Moriyama Yuichiro Ito Yuta Harada Hiroki Dodo Kana Kumahara Tatsuji Yogi Noritsugu Ohashi Reiji Higashi Akihiro Mori Source Type: research

Antimicrobial resistance patterns of common Gram-negative microorganisms isolated from patients with lower respiratory tract infection in a Teaching Hospital in Vietnam
Jpn J Infect Dis. 2024 Jan 31. doi: 10.7883/yoken.JJID.2023.260. Online ahead of print.ABSTRACTThis cross-sectional study investigated the antimicrobial resistance (AMR) patterns of Gram-negative pathogens isolated from 4,789 hospitalized patients with lower respiratory tract infections (LRTIs). Of the collected specimens, 1,325 (27.7%) specimens tested positive for Gram-negative bacteria. The most prevalent isolates were Acinetobacter baumannii (38.6%), Pseudomonas aeruginosa (33.5%), Klebsiella pneumoniae (18.7%), Escherichia coli (5.6%), and Klebsiella aerogenes (3.5%). Antimicrobial resistance analysis revealed high re...
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Hoang Huy Le An Van Nguyen Luong Huy Vu Vinh Thi Ha Nguyen Hoa Quynh Pham Hung Van Le Son Thai Nguyen Hong Thu Le Hung Viet Dinh Nam Van Le Tuan Dinh Le Minh Nhat Le Viet Hoang Nguyen Kien Trung Hoang Hai Ha Long Le Source Type: research

Relationship of toll-like receptor 7, 9 and 10 polymorphisms on the severity of COVID-19
In this study, we investigated frequencies of TLR7 (C.4-151 A/G), TLR9 (T-1486C and G2848A), and TLR10 (720A/C and 992T/A) single nucleotide polymorphisms (SNPs) in 150 cases with COVID-19 and 171 control samples. We also observed whether TLR7, 9, and 10 were related with the COVID-19 disease severity. Furthermore, we analyzed the association between COVID-19 and some clinical parameters. Polymerase chain reaction (PCR) based on restriction fragment length polymorphism (RFLP) was performed for TLR7, 9 and 10 SNPs. TLR7 C.4-151 A/G G allele and GG genotype; TLR9 T-1486C C allele and TC, CC genotypes; and TLR10 720A/C C alle...
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Burcu Bayyurt Sevgi Baltac ı Nil Özbilüm Şahin Serdal Arslan Mehmet Bak ır Source Type: research

Biofilm eradication of Stenotrophomonas maltophilia by Levofloxacin and Trimethoprim-sulfamethoxazole
In conclusion, S. maltophilia isolated from blood had higher biofilm production than those from respiratory samples. Resistance to antibiotics increased due to biofilm production. Antibiotic monotherapy might not be the best course of action for the treatment of S. maltophilia infections in Mexico, as they might also be causing biofilm production.PMID:38296539 | DOI:10.7883/yoken.JJID.2023.389 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Jos é Mauricio Del Río-Chacón Fabi án Rojas-Larios Paola Bocanegra-Ibarias Daniel Salas-Trevi ño Francisco Espinoza-G ómez Adri án Camacho-Ortiz Samantha Flores-Trevi ño Source Type: research

Efficacy of cefiderocol, a novel siderophore cephalosporin, against multi-drug resistant Acinetobacter baumannii clinical isolates in Japan
In conclusion, this study showed that susceptibility to cefiderocol of MDRAB clinical isolates in Japan was equivalent to that of colistin or tigecycline. Cefiderocol could be a possible choice for the treatment of MDRAB infections.PMID:38296540 | DOI:10.7883/yoken.JJID.2023.364 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Yoshitaka Kimura Nami Hatayama Yoshinori Sato Satoshi Nishida Yusuke Yoshino Source Type: research

Inactivation of SARS-CoV-2 in serum using physical methods
In this study, serum samples containing SARS-CoV-2 were subjected to heat, UV irradiation, and gamma irradiation to determine their inactivation conditions. The viral titers were below the detection limit after heating at 56°C for 1 h or 60°C for 15 min, UV-B irradiation with a transilluminator for 30 min, or gamma ray irradiation with 60Co at 10 kGy. These results provide useful information for safe serological and biochemical experiments.PMID:38296541 | DOI:10.7883/yoken.JJID.2023.349 (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - January 31, 2024 Category: Infectious Diseases Authors: Toshihiko Harada Hirofumi Fujimoto Shuetsu Fukushi Koji Ishii Ken-Ichi Hanaki Source Type: research