The Phantom Menace for the Patients with Hepatobiliary Diseases: Shewanella haliotis, often Misidentified as Shewanella algae by Biochemical Tests and MALDI-TOF.
Abstract Although Shewanella algae has been known for weak pathogenicity, case reports have been steadily increased. Shewanella algae and Shewanella haliotis are not easy to distinguish by conventional phenotypical methods. We reviewed microbiological and clinical features of S. algae and S. haliotis infections in our institute. Bacterial culture and identification reports from patient samples from 2010 to 2014 were reviewed to screen the cases of Shewanella infections. In addition to conventional biochemical tests, 16S rRNA gene sequence analysis and MALDI-TOF were performed with 19 bacterial isolates stored. Med...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Byun JH, Park H, Kim S Tags: Jpn J Infect Dis Source Type: research

Rapid detection and typing of carbapenemase-producing genes from carbapenem-resistant Enterobacteriaceae isolates collected in a Japanese hospital using the Xpert(TM) Carba-R assay.
PMID: 27580570 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Uwamino Y, Sugita K, Hasegawa N, Nishimura T, Fujiwara H, Iwata S Tags: Jpn J Infect Dis Source Type: research

Prospective epidemiological evaluation of seasonal influenza in all elementary schoolchildren in Matsumoto City, Japan, in 2014/2015.
Abstract Seasonal influenza is known to spread within and among educational organizations. Detailed understanding of the pattern of infection requires prospective epidemiological studies among all schools in a community. This prospective survey evaluated 13,217 schoolchildren attending all 29 public elementary schools in Matsumoto City, Japan, in 2014/2015. Questionnaires were distributed to school nurses to obtain information about onset date and suspected route of transmission of influenza of all schoolchildren diagnosed at medical institutions. Responses were obtained regarding 2,548 infected individuals, repre...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Uchida M, Kaneko M, Hidaka Y, Yamamoto H, Honda T, Takeuchi S, Saito M, Kawa S Tags: Jpn J Infect Dis Source Type: research

Antimicrobial susceptibility and molecular epidemiology of multidrug-resistant Klebsiella pneumoniae in Central China.
This study investigated the epidemiology and resistance profiles of K. pneumoniae strains isolated in Central China between 2009 and 2014. Antimicrobial susceptibility tests and polymerase chain reaction were used to investigate the prevalence and resistance of ESBLs and carbapenemases produced by K. pneumoniae, and the prevalence of KPC-producing K. pneumoniae was investigated by multilocus sequence typing. Carbapenem resistance has emerged as the main concern in K. pneumoniae infections, with phenotype tests detecting carbapenemases in nearly 20% of isolates. KPC-producing isolates were clonally related in a local epidem...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Guo X, Cao Z, Dai Z, Li Y, He X, Hu X, Tian F, Ren Y Tags: Jpn J Infect Dis Source Type: research

Shiga Toxin Subtypes and Virulence Genes Distributed among Escherichia coli Isolated from Cattle.
Abstract Subtypes of stx1 and stx2 carried in 45 Shiga toxin-producing Escherichia coli (STEC) strains isolated from cattle were investigated using PCR. Only subtype stx1a was detected among all the stx1-positive strains. The major stx2 subtype was stx2a, and followed by stx2d, stx2c, stx2b and stx2g in decreasing order. stx2c was found in the strains of O157 and O174. stx2d was found in 11 strains; they were confirmed using DNA sequencing to carry both the activatable tail and the END motif, all of which were eae-negative and three contained stx2d as the only stx. stx2g was found in two strains in association wit...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Akiyama Y, Futai H, Saito E, Ogita K, Sakae H, Fukunaga M, Tsuji H, Chikahira M, Iguchi A Tags: Jpn J Infect Dis Source Type: research

Synergistic effect of TNF- α and dengue virus infection on adhesion molecule reorganization in human endothelial cells.
In conclusion, the synergistic effect of TNF-α and DENV induced permeability changes in endothelial cells. These results will improve better understanding of the mechanisms of enhanced vascular permeability in DENV infection. PMID: 27580574 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Inyoo S, Suttitheptumrong A, Pattanakitsakul SN Tags: Jpn J Infect Dis Source Type: research

Clinical and diagnostic aspects of brucellosis and antimicrobial susceptibility of Brucella isolates in Hamedan, Iran.
Abstract Current drug regimens for brucellosis are associated with relatively high rates of therapeutic failure or relapse. Reduced antimicrobial susceptibility of Brucella spp. has been proposed recently as a potential cause of therapeutic failure. The aim of this study was to evaluate the antibiotic resistance pattern of Brucella melitensis clinical isolates by E-test method in Hamadan, west of Iran. In a 15-month period, all patients with suspected brucellosis were enrolled. Blood Specimens were collected for diagnosis of brucellosis by BACTEC system and serological tests. Antimicrobial susceptibility of clinic...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Asadi FT, Hashemi SH, Alikhani MY, Moghimbeigi A, Naseri Z Tags: Jpn J Infect Dis Source Type: research

A comparative evaluation of the serological and molecular methods for the diagnosis of scrub typhus in Indian settings.
Abstract The major brunt of Scrub typhus is borne by the developing countries like India but the disease still remains neglected. The rapid progression to fatal complications and associated mortality calls for improved diagnostic services. IgM Immunofluorescence assay (IFA) with all its limitations is still the gold standard. Out of 218 suspected cases enrolled in the 2 year study period, 30 cases of scrub typhus were detected by IgM IFA at 1:64 dilution. The sensitivity of IgM Enzyme linked immunosorbant assay (ELISA), IgM Rapid Flow assay (RFA) and IgG RFA was found to be 97%, 87% and 77% respectively. Their res...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Gupta N, Chaudhry R, K Kabra S, Lodha R, R Mirdha B, K Das B, Dey AB, Sreenivas V Tags: Jpn J Infect Dis Source Type: research

Prevalence and characteristics of Salmonella and Campylobacter in retail poultry meat in Japan.
This study was undertaken to determine the prevalence, antimicrobial susceptibility, and genetic relatedness of Salmonella enterica subsp. enterica and Campylobacter spp. in poultry meat, and to analyze the association of genetic types of these bacteria with their geographical distribution and antimicrobial resistance profiles. Fifty-four and 71 of 100 samples were found to be contaminated with Salmonella and Campylobacter, respectively. Nine Salmonella serotypes were found, including S. enterica subsp. enterica serovar Infantis (33%), Schwarzengrund (12%), Manhattan (9%), and others. Campylobacter jejuni and C. coli were ...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Furukawa I, Ishihara T, Teranishi H, Saito S, Yatsuyanagi J, Wada E, Kumagai Y, Takahashi S, Konno T, Kashio H, Kobayashi A, Kato N, Hayashi KI, Fukushima K, Ishikawa K, Horikawa K, Oishi A, Izumiya H, Ohnishi T, Konishi Y, Kuroki T Tags: Jpn J Infect Dis Source Type: research

Third-generation cephalosporin-resistant non-typhoidal Salmonella isolated from human feces in Japan.
Abstract Detection and characterization of β-lactamase genes in a total of ten non-typhoidal Salmonella (NTS) clinical isolates exhibiting resistance to the third-generation cephalosporins collected during 2012 -2014 in Japan were conducted. Among five strains with cefotaxime MIC (minimum inhibitory concentration) ≥64 μg/ml and positive results of clavulanic acid inhibition effect, blaCTX-M-2 was detected in three strains (serotypes Stanley and Muenchen), and each of blaTEM-52 (serotype Manhattan) and blaSHV-12 (serotype Infantis) was found in one strain. The blaCMY-2 was detected in all of the remainin...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Saito S, Koori Y, Ohsaki Y, Osaka S, Oana K, Nagano Y, Arakawa Y, Nagano N Tags: Jpn J Infect Dis Source Type: research

Isolation and characterization of an Escherichia albertii producing three different toxins from a child with diarrhea.
Abstract Here, we show that a bacterium isolated as a sole pathogen from a child with diarrhea harbor eae and 2 different cytolethal distending toxin genes (cdt) homologous to Escherichia coli cdt-I and cdt-II genes, respectively. The bacterium was originally identified as atypical E. coli by conventional biochemical tests. However, this bacterium was finally identified as E. albertii by multilocus sequence analysis, which is an only method being able to clearly differentiate E. coli from E. albertii. Shiga toxin 2f (stx2f) genes were also detected in the strain. Production of the 3 toxins was confirmed by cytotox...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Hinenoya A, Yasuda N, Hibino T, Shima A, Nagita A, Tsukamoto T, Yamasaki S Tags: Jpn J Infect Dis Source Type: research

Gonococcal Antimicrobial Susceptibility and Prevalence of blaTEM-1, blaTEM-135 Genes in Thailand.
Abstract We studied antimicrobial susceptibility and the current rates of blaTEM-1 and blaTEM-135. Neisseria gonorrhoeae 370 isolates were tested by using disk diffusion method and found 100% susceptible to cefixime, ceftriaxone, cefotaxime, ceftazidime, cefepime, spectinomycin and azithromycin. They were resistant to penicillin (85.7%), ciprofloxacin (88.0%), ofloxacin (97.4%), and tetracycline (89.1%). Penicillinase-producing N. gonorrhoeae (PPNG) was 83.8% which 70.0% was further identified as PPNG plus tetracycline resistant N. gonorrhoeae, with 13.8% being PPNG alone. Penicillin, tetracycline and ciprofloxaci...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Tribuddharat C, Pongpech P, Charoenwatanachokchai A, Lokpichart S, Srifuengfung S, Sonprasert S Tags: Jpn J Infect Dis Source Type: research

Presence of Antibodies against Severe Fever with Thrombocytopenia Syndrome Virus in Non-endemic Areas, China.
According to this study, we suggested that health education should be enhanced to increase residents (especially the older ones and tea pluckers) awareness in order to protect them against SFTS viral infection. PMID: 27580581 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Huang X, Zhang Z, Jin G, Wang X, Tan C, Yin H, Wang S Tags: Jpn J Infect Dis Source Type: research

Prevalence and characteristics of pediatric healthcare workers without immunity to varicella zoster virus.
This study aimed to determine the proportion of varicella non-immune pediatric healthcare workers (HCWs) of Pediatrics Department, King Chulalongkorn Memorial Hospital and to determine cost effective strategies to identify non-immune personnel. A cross-sectional study, using a self-administered questionnaire to determine history of chickenpox or 2-dose varicella vaccination was conducted. From a total of 699 HCWs, 653 HCWs (93%) including 145 physicians (22%), 297 nurses (46%) and 211 administrative staff (32%) responded to questionnaires. There were 475 HCWs (73%) who had a history of chickenpox, 58(9%) who had completed ...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Anugulruengkitt S, Puthanakit T, Siengboon S, Paitoonpong L, Kowitdamrong E, Pancharoen C, Pichitchok Y Tags: Jpn J Infect Dis Source Type: research

Large-scale one-year survey of Trichinella spp. infection in wild boar (Sus scrofa) in Japan.
This study presents the results of a large-scale one-year survey of Trichinella spp. in Japanese wild boar (Sus scrofa). We analyzed the tongues of 1168 wild boars captured by hunters in 30 prefectures of Japan, most of which were boar habitats, from October 2014 to January 2015. The samples were digested, and the Trichinella spp. muscle larvae prevalences were examined. Pooled samples from 10 individuals (15 g per head) and 117 randomly selected samples (10% of the total samples) that were processed individually showed no larval infection. Thus, most Japanese wild boar do not play a major role in the sylvatic cycle of Tri...
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Hatta T, Imamura K, Yamamoto T, Matsubayashi M, Tsuji N, Tsutsui T Tags: Jpn J Infect Dis Source Type: research

No evidence of rat hepatitis E virus excretion into urine of rats.
Abstract To investigate whether rat hepatitis E virus (rat HEV) is excreted into the urine of rats, we infected three Wistar and six nude rats with rat HEV and examined the rat HEV RNA in serum, fecal and urine samples. We detected rat HEV RNA in the serum and fecal samples of all rats but not in the urine. Our results suggest that in rats, rat HEV is not transmitted via urine. PMID: 27580584 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 31, 2016 Category: Infectious Diseases Authors: Li TC, Yoshizaki S, Ami Y, Suzaki Y, Johne R, Wakita T Tags: Jpn J Infect Dis Source Type: research

Reply to the Letter to the Editor from R. Calero-Bernal et al.
os JM PMID: 27534716 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 19, 2016 Category: Infectious Diseases Authors: Egea MA, Herraez O, Tenias JM, Garduño E, Huertas M, Carranza R, Ramos JM Tags: Jpn J Infect Dis Source Type: research

Survey of Zoonoses in Extremadura, Spain.
PMID: 27534717 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 19, 2016 Category: Infectious Diseases Authors: Calero-Bernal R, Delgado de Las Cuevas G Tags: Jpn J Infect Dis Source Type: research

Reply to the Letter to the Editor from H. Watson et al.
PMID: 27534718 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 19, 2016 Category: Infectious Diseases Authors: Shon C, Lee KS, Kim YE, Park SY, Oh IH Tags: Jpn J Infect Dis Source Type: research

Economic Burden of Hepatitis in South Korea.
PMID: 27534719 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 19, 2016 Category: Infectious Diseases Authors: Watson H, Minini P, Encinas J Tags: Jpn J Infect Dis Source Type: research

A Epidemiological Investigation of a Nosocomial Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Critical Care Center in Japan, 2011-2012.
Abstract Volume 69, no. 2, p. 143-148, 2016. Page 143, Title should appear as shown below.An Epidemiological Investigation of a Nosocomial Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Critical Care Center in Japan, 2011-2012. PMID: 27452226 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - July 29, 2016 Category: Infectious Diseases Authors: Ushizawa H, Yahata Y, Endo T, Iwashima T, Misawa M, Sonobe M, Yamagishi T, Kamiya H, Nakashima K, Matsui T, Matsui M, Suzuki S, Shibayama K, Doi M, Irie F, Yamato S, Otomo Y, Oishi K Tags: Jpn J Infect Dis Source Type: research

Detection of Enteric Viruses in Fecal Specimens from Nonbacterial Foodborne Gastroenteritis Outbreaks in Tokyo, Japan between 1966 and 1983.
Abstract We investigated the prevalence of five enteric viruses (norovirus [NoV], sapovirus [SAV], rotavirus, astrovirus, and adenovirus) in archived stool specimens collected from 70 foodborne gastroenteritis outbreaks in Tokyo, Japan that occurred from 1966 to 1983 and genetically characterized these viruses. NoV was detected in 48 (68.6%) outbreaks, while SaV, group C rotavirus (RVC), and astrovirus were detected in one (1.4%) outbreak each. Based on the partial capsid sequences, the detected NoVs were classified as the following genotypes: nine genogroup I (GI; GI.1-6, GI.8, GI.9, and GI.NA), 13 GII (GII.1-9, ...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Mori K, Nagano M, Kimoto K, Somura Y, Akiba T, Hayashi Y, Sadamasu K, Kai A Tags: Jpn J Infect Dis Source Type: research

The Epidemic of HIV, HCV and Syphilis and the Correlates of Sexual Transmitted Infections among Men Who Have Sex with Men in Zhenjiang, Jiangsu, China.
Abstract To investigate the epidemic of HIV, HCV and syphilis, HIV-1 subtype among men who have sex with men (MSM) and to measure factors that correlated with sexual transmitted infections (STIs), a cross-sectional survey was conducted among 657 MSM in Zhenjiang, Jiangsu, during 2012-2013. Social-demographic characterization and risky behaviors were collected and blood samples were obtained. In this survey, the prevalence of STIs of HIV (5.3%), HCV (0.6%) and syphilis (19.2%) were measured. Of 35 HIV-infected MSM, 1 (0.2%) and 17 (2.6%) were co-infected with HCV and syphilis. Among 33 samples with available HIV-1 ...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Shen L, Liu X, Fu GF, Hao S, Zhang M, Wang T, Yang J, Wu X, Mao L Tags: Jpn J Infect Dis Source Type: research

Immunity to diphtheria and tetanus in Army personnel and adult civilians in Mashhad, Iran.
This study aimed to determine serologic immunity to diphtheria and tetanus in army personnel and a sample of adult civilians in Mashhad, Iran. Army personnel (n=180) and civilians (n=83) of whom presented at Mashhad army hospital participated in this study. Diphtheria and tetanus antitoxins levels were determined by enzyme-linked immunosorbent assay. About 77% and 94% of army personnel aged 18-34 years had at least basic protection to diphtheria (antitoxin level ≥0.1 IU/ml) and tetanus (antitoxin level>0.1 IU/ml), respectively. For civilians of this age group, these proportions were 76% for both diseases. Antitoxins ...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Hosseini Shokouh SJ, Mohammadi B, Rajabi J, Mohammadian Roshan G Tags: Jpn J Infect Dis Source Type: research

HIV testing in Non-Injection Drug Users: prevalence and associated factors.
CONCLUSION: The determinants for HIV testing must be taken into account when planning prevention and programming strategies, including the widening of testing coverage among NIDU, educational health actions, links between sexually transmitted infections prevention services and addiction treatment services and the use of rapid tests to help people that are in contact with the virus learn about their HIV status, enter treatment, and improve their quality of life. PMID: 27357979 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Guimarães RA, Lucchese R, Fernandes IL, Vera I, Rodovalho AG, Guimarães VA, Silva GC, de Felipe RL, de Castro PA, Ferreira PM Tags: Jpn J Infect Dis Source Type: research

Genetic analysis of HIV-1 in Japan: A comprehensive analysis of donated blood.
CONCLUSIONS: Analysis of phylogenic trees suggested that the local outbreaks have become smaller in Japan; however, intermixing of viral types between these two areas was more evident in the more recent samples. PMID: 27357980 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Matsumoto C, Shinohara N, Sobata R, Uchida S, Satake M, Tadokoro K Tags: Jpn J Infect Dis Source Type: research

Characteristics of Multidrug-resistant Corynebacterium spp. Isolated from Blood Cultures from Hospitalized Patients in Japan.
We reported the epidemiological investigation of Corynebacterium spp. isolated from bloodstream specimens in Kurume University Hospital, between June 2008 and July 2011. Twenty-two Corynebacterium spp. likely isolates were isolated from 22 hospitalized patients, of which 12 (54.5%) strains were identified as Corynebacterium striatum. Minimum inhibitory concentration tests were performed after biochemical and genotypic identifications. Biofilm productions were detected using a 96-well microplate assay. The dissemination of Corynebacterium striatum was investigated by pulsed-field gel electrophoresis. All strains showed a te...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Qin L, Sakai Y, Bao R, Xie H, Masunaga K, Miura M, Hashimoto K, Tanamachi C, Hu B, Watanabe H Tags: Jpn J Infect Dis Source Type: research

Canine echinococcosis due to Echinococcus multilocularis: a second notifiable case from mainland Japan.
PMID: 27357982 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Morishima Y, Tomaru Y, Fukumoto SI, Sugiyama H, Yamasaki H, Hashimoto C, Harada K Tags: Jpn J Infect Dis Source Type: research

Development of a novel Loop-Mediated Isothermal Amplification (LAMP) assay for Rickettsia spp.
Abstract We developed a novel loop-mediated isothermal amplification (LAMP) detection method for Rickettsia spp., including Rickettsia prowazekii and Rickettsia typhi. Species-specific LAMP primers were developed for orthologous genes conserved among Rickettsia spp. The selected modified primers could detect all the Rickettsia spp. tested. Thus, the LAMP method was successfully used to detect 100 DNA copies of Rickettsia spp. within approximately 60 min at 63°C. This method may be an excellent tool for the early diagnosis of rickettsiosis in laboratory or in the field. PMID: 27357983 [PubMed - as supplied...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Hanaoka N, Matsutani M, Satoh M, Ogawa M, Shirai M, Ando S Tags: Jpn J Infect Dis Source Type: research

Histopathologic findings of lung with A/H1N1pdm09 infection-associated ARDS in the post-pandemic season.
In conclusion, pathological and molecular biological examinations revealed that an A/H1N1pdm09 infection-associated ARDS case in the post-pandemic season was not caused by direct alveolar epithelial damage due to viral infection, but rather by indirect damage of endothelial cells due to severe sepsis. PMID: 27357984 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Hayashi K, Yoshida H, Sato Y, Tobiume M, Suzuki Y, Ariyoshi K, Hasegawa H, Nakajima N Tags: Jpn J Infect Dis Source Type: research

High antiretroviral coverage and viral suppression prevalence in Japan: an excellent profile for downstream HIV care spectrum.
Abstract To understand the effectiveness of Japan's health care system for HIV/AIDS, including prevention, diagnosis, access to antiretroviral treatment, and treatment outcomes, clinical information on HIV/AIDS cases was collected through questioners sent to 377 registered HIV/AIDS clinics in Japan. The data were collected in 2009 and 2014, and 9,040 and 14,569 cases were obtained, respectively. Prevalence of on-treatment cases linked to care were 69.6% and 87.8% in 2009 and 2014, respectively, demonstrating improvement in treatment coverage over the recent 5 years. The proportion of cases with undetectable HIV RN...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Miyazaki N, Sugiura W, Gatanaga H, Watanabe D, Yamamoto Y, Yokomaku Y, Yoshimura K, Matsushita S, Japanese HIV-MDR Study Group Tags: Jpn J Infect Dis Source Type: research

Accuracy of stick-type kit and enzyme-linked immunosorbent assay for the detection of urinary Helicobacter pylori antibodies in a population of Japan Sea region of northern Japan.
Abstract In Japan, both a novel stick-type kit and ELISA kit are available for detection of antibody to Helicobacter pylori (H. pylori) in urine. However, the accuracy of these tests has not been fully examined in northern Japanese populations. Urine samples from 359 subjects were tested using a novel stick-type urinary H. pylori-antibody detection kit (RAPIRUN), while samples from 200 subjects were tested using an ELISA-based test (URINELISA). Prevalence of H. pylori infection was tested by (13)C-urea breath test (UBT) and a monoclonal antibody-based stool antigen test (TPAg). Subjects were considered to have the...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Shimoyama T, Sawada Y, Sawada N, Chinda D, Fukuda S Tags: Jpn J Infect Dis Source Type: research

The first case report of cerebral cyst infection due to Helicobacter cinaedi.
We report the first case of cerebral cyst infection of H. cinaedi, a fastidious spiral-shaped gram-negative rod bacterium.A 70-year-old man visited our hospital with a fever persisting for 2 weeks. He had received surgery and radiotherapy for parapharyngeal space squamous cell carcinoma 10 years ago. The radiotherapy had resulted in a cerebral cyst as a side effect, and an Ommaya reservoir had been inserted into the cyst. Blood culture and analysis of the brain cyst fluid revealed the presence of spiral-shaped gram-negative rod bacteria, which were identified as Helicobacter cinaedi by polymerase chain reaction.We first ad...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Abiko S, Nakamura I, Yamaguchi Y, Ohkusu K, Hirayama Y, Matsumoto T Tags: Jpn J Infect Dis Source Type: research

Bacteremia due to Arthrobacter creatinolyticus in an elderly diabetic man with acute cholangitis.
Abstract Arthrobacter species are gram-positive, aerobic, catalase-positive, coryneform bacteria belonging to the family Microbacteriaceae. An 87-year-old man with poorly controlled diabetic mellitus presented with fever, bedsores, and elevated hepatobiliary enzyme levels. He was diagnosed with bacteremia due to coryneform gram-positive bacilli with acute cholangitis. Doripenem and subsquencial sulbactum/ampicillin treatment were used for acute cholangitis, and the bacteremia was treated with 2 weeks of vancomycin treatment. The bacteremia was misidentified by phenotyping assay (API Coryne test), but was identifie...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Yamamoto K, Hayakawa K, Nagamatsu M, Fujiya Y, Mawatari M, Kutsuna S, Takeshita N, Tamura S, Mezaki K, Ohmagari N Tags: Jpn J Infect Dis Source Type: research

Elevated serum thymic stromal lymphopoietin found in wheezing children infected with human metapneumovirus.
This study was conducted to study the epidemiology and clinical manifestations of human metapneumovirus (hMPV) infection in children in the Suzhou area, China, and to investigate the effect of thymic stromal lymphopoietin (TSLP) on wheezing in hMPV-infected children. The study comprised 13 533 children with respiratory tract infection admitted to Children's Hospital of Soochow University between January 2009 and December 2014. Clinical data was recorded. The plasma levels of TSLP, IL4, and IL2 in 35 wheezing children with single hMPV infection and 15 non-wheezy children with hMPV infection and 35 wheezing children w...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Gu W, Wang Y, Hao C, Zhang X, Yan Y, Chen Z, Jiang W, Shao X, Ji W Tags: Jpn J Infect Dis Source Type: research

Regional Variations in the Incidence of Rotavirus Hospitalizations between Children Living in Defined regions of Akita and Kyoto Prefectures, Japan.
This study aimed at determining the incidence rates of rotavirus hospitalizations among children age
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Noguchi A, Ito H, Miura S, Fujii Y, Katayama K, Nakagomi T, Nakagomi O, Takahashi T Tags: Jpn J Infect Dis Source Type: research

Immune Response to Mumps Virus in Iranian Unvaccinated Young Adults.
Abstract Although first mumps vaccine was licensed many years ago, mumps vaccine added to Iran's Expanded Program on Immunization in 2003. Therefore, majority of Iranian young adults born before 2003 are unvaccinated and their immunity resulted of natural infection. For evaluation of cellular responses against mumps virus following natural infection, we investigated ninety Iranian unvaccinated young adults aged 20-30 years. Mumps specific memory CD4+ and CD8+ proliferation and frequency of cytotoxic lymphocyte CD8+ CD107a were evaluated using sensitive technique of flowcytometery. Our results showed thirty three o...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Keshavarz M, Shafiee A, Nicknam MH, Khosravani P, Yousefi A, Izad M Tags: Jpn J Infect Dis Source Type: research

HeLa-ACE2-TMPRSS2 cells are useful for the isolation of Human Coronavirus 229E.
PMID: 27357992 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Matoba Y, Aoki Y, Tanaka S, Yahagi K, Katsushima Y, Katsushima F, Sugawara K, Matsuzaki Y, Mizuta K Tags: Jpn J Infect Dis Source Type: research

An imported-case of scrub typhus from South Korea to Yamagata, Japan.
PMID: 27357993 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Suzuki Y, Shimanuki M, Seto J, Yahagi K, Mizuta K Tags: Jpn J Infect Dis Source Type: research

Co-colonization with Neisseria species is a risk factor for prolonged colonization with multidrug-resistant Acinetobacter baumannii in the respiratory tract.
Abstract Multidrug-resistant Acinetobacter baumannii (MDRAB) colonization increases the risk of spread in the hospital setting. The impact of clinical factors, including antibiotic use, on prolongation of MDRAB colonization has not been investigated. All patients with respiratory tract MDRAB based on culture were enrolled. Long-term colonizers and short-term colonizers were defined as patients whose colonization periods were>30 days or ≤30 days, respectively. Clinical data were abstracted from medical records. MDRAB were isolated in 34 patients. There were 13 long-term colonizers and nine short-term colonize...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Kitazawa T, Seo K, Yoshino Y, Koga I, Ota Y Tags: Jpn J Infect Dis Source Type: research

A Novel Isolation of Mycoplasma amphoriforme from a Pediatric Patient with Protracted Bronchitis in Japan.
PMID: 27357995 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Katsukawa C, Asai S, Mizutani K, Arai K, Kohdera U, Kushibiki C, Shiomi M, Takeda Y, Naka A, Nakano K, Matsushita T, Takahashi K Tags: Jpn J Infect Dis Source Type: research

Intranasal Inactivated Influenza Vaccines: a Reasonable Approach to Improve the Efficacy of Influenza Vaccine?
Abstract Influenza is a contagious, acute respiratory disease caused by the influenza virus. The mucosal lining in the host respiratory tract is not only the site of virus infection, but also the site of defense; it is at this site that the host immune response targets the virus and protects against reinfection. One of the most effective methods to prevent influenza is to induce specific antibody (Ab) responses in the respiratory tract by vaccination. Two types of influenza vaccines, intranasal live attenuated influenza virus (LAIV) vaccines and parenteral (injectable) inactivated vaccines, are currently used worl...
Source: Japanese Journal of Infectious Diseases - May 25, 2016 Category: Infectious Diseases Authors: Tamura S, Ainai A, Suzuki T, Kurata T, Hasegawa H Tags: Jpn J Infect Dis Source Type: research

Geo-Demography of HIV/AIDS in Japan from 1985 to 2011: Incidence and Transmission Mode under Influence of Population Size/Density.
Abstract Volume 69, no. 2, p. 97-108, 2016. Page 107, Figure 11 should appear as shown below. PMID: 27212585 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - May 25, 2016 Category: Infectious Diseases Authors: Yoshikura H Tags: Jpn J Infect Dis Source Type: research

Verification of the Overestimation of the "Deaths Associated with Influenza Pandemic of 1918-1919, Japan" Claimed in a Demographic Study.
Verification of the Overestimation of the "Deaths Associated with Influenza Pandemic of 1918-1919, Japan" Claimed in a Demographic Study. Jpn J Infect Dis. 2016;69(1):12-7 Authors: Nishimura H, Ohkusa Y Abstract Official records show that the Japanese influenza death toll in 1918-1920 was 385 thousand. However, a recently published study claims that the records are skeptical, claiming the figure to be "an anomaly by Asian standard," and re-estimated the number to be about 2 million by its unique demographical calculation. However, it is not sound from the following socio-historical...
Source: Japanese Journal of Infectious Diseases - May 20, 2016 Category: Infectious Diseases Authors: Nishimura H, Ohkusa Y Tags: Jpn J Infect Dis Source Type: research

Cryptococcosis in anti-interferon-gamma autoantibodies-positive patients: a different clinical manifestation from HIV-infected patients.
Abstract Disseminated nontuberculous mycobacterial (NTM) infection is the most common feature in patients positive for anti-interferon-gamma autoantibodies (IFN-γ Ab). Cryptococcus co-infects these patients. A retrospective, matched case-control study was conducted at Srinagarind Hospital between 1992 and 2013. We reviewed the charts of non-HIV-infected patients with cryptococcosis with disseminated NTM (case) and matched 2 HIV-infected patients (control) with cryptococcosis for each case. There were 16 cases and 32 controls. Among the 10 of 16 cased patients whose sera were available for testing, all were p...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Chetchotisakd P, Anunnatsiri S, Nithichanon A, Lertmemongkolchai G Tags: Jpn J Infect Dis Source Type: research

Severe Fever with Thrombocytopenia Syndrome Virus antibody investigation among domestic bovine transported to slaughterhouse in Shimane Prefecture, Japan.
PMID: 27169939 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Tabara K, Fujita H, Hirata A, Hayasaka D Tags: Jpn J Infect Dis Source Type: research

Streptozotocin-induced hyperglycaemic mice are susceptible to invasive enteric bacterial infection.
Abstract Diabetes mellitus and diarrhoea are increasingly becoming a global burden especially in developing countries like India. Diabetic patients are observed to be susceptible to the pathogenic bacteria particularly invasive enteric bacterial infection. Our study was designed on changes in pathophysiological parameters observed in streptozotocin-induced hyperglycaemic mice. In our experiments we infected streptozotocin treated hyperglycemic mice and control mice with different enteric pathogenic bacteria: non-typhoidal Salmonella, Shigella and Vibrio parahaemolyticus. Morbidity, mortality and bacterial load wer...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Koley H, Ghosh P, Sinha R, Mitra S, Mukherjee P, Howlader DR, Chaki C, Nag D Tags: Jpn J Infect Dis Source Type: research

Multi-typing of enterobacteria harboring lt and st enterotoxin genes isolated from mexican children.
MULTI-TYPING OF ENTEROBACTERIA HARBORING LT AND ST ENTEROTOXIN GENES ISOLATED FROM MEXICAN CHILDREN. Jpn J Infect Dis. 2016 May 9; Authors: Vázquez-Marrufo G, Rosales-Castillo JA, Robinson-Fuentes VA, Tafolla-Muñoz I, Carreras-Villaseñor N, Vázquez-Garcidueñas MS Abstract ETEC is the most common cause of diarrhea in children under 5 years from developing world. We used the sequencing of the 16S rRNA gene, the Biolog® system, and the Amplified Ribosomal DNA Restriction Analysis (ARDRA), to identify 69 Enterobacteria isolated from feces of healthy children up to 12...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Vázquez-Marrufo G, Rosales-Castillo JA, Robinson-Fuentes VA, Tafolla-Muñoz I, Carreras-Villaseñor N, Vázquez-Garcidueñas MS Tags: Jpn J Infect Dis Source Type: research

Serum from Nipah virus patients recognises recombinant viral proteins produced in Escherichia coli.
Abstract The genes for Nipah virus (NiV) N, F and G proteins were amplified from viral RNA, cloned into the plasmid pTriEx-3 Hygro, expressed and purified using immobilized metal affinity chromatography. The recombinant NiV proteins, rNiV-N, rNiV-F and rNiV-G, were successfully expressed in E. coli and purified with a yield of 4mg/L, 16mg/L and 4mg/L, respectively. All three recombinant viral proteins reacted with all 19 NiV-positive human sera with rNiV-N and rNiV-G being more immunogenic. The recombinant viral proteins did not react with any of the 12 NiV-negative sera. Serum from a case of late-onset relapsing ...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Tiong V, Lam CW, Phoon WH, AbuBakar S, Chang LY Tags: Jpn J Infect Dis Source Type: research

Epidemiological and clinical characteristics of patients with Middle East Respiratory syndrome Coronavirus in Iran in 2014.
In conclusion, we insist that all patients with acute respiratory symptoms, who had contact with a person that had recently traveled to Saudi-Arabia and experienced respiratory infection, should be investigated for MERS-CoV. PMID: 27169943 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Yousefi M, Dehesh MM, Farokhnia M Tags: Jpn J Infect Dis Source Type: research