Reply to the Letter to the Editor from R. Calero-Bernal et al.
os JM PMID: 27534716 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 19, 2016 Category: Infectious Diseases Authors: Egea MA, Herraez O, Tenias JM, Garduño E, Huertas M, Carranza R, Ramos JM Tags: Jpn J Infect Dis Source Type: research

Survey of Zoonoses in Extremadura, Spain.
PMID: 27534717 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 19, 2016 Category: Infectious Diseases Authors: Calero-Bernal R, Delgado de Las Cuevas G Tags: Jpn J Infect Dis Source Type: research

Reply to the Letter to the Editor from H. Watson et al.
PMID: 27534718 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 19, 2016 Category: Infectious Diseases Authors: Shon C, Lee KS, Kim YE, Park SY, Oh IH Tags: Jpn J Infect Dis Source Type: research

Economic Burden of Hepatitis in South Korea.
PMID: 27534719 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - August 19, 2016 Category: Infectious Diseases Authors: Watson H, Minini P, Encinas J Tags: Jpn J Infect Dis Source Type: research

A Epidemiological Investigation of a Nosocomial Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Critical Care Center in Japan, 2011-2012.
Abstract Volume 69, no. 2, p. 143-148, 2016. Page 143, Title should appear as shown below.An Epidemiological Investigation of a Nosocomial Outbreak of Multidrug-Resistant Acinetobacter baumannii in a Critical Care Center in Japan, 2011-2012. PMID: 27452226 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - July 29, 2016 Category: Infectious Diseases Authors: Ushizawa H, Yahata Y, Endo T, Iwashima T, Misawa M, Sonobe M, Yamagishi T, Kamiya H, Nakashima K, Matsui T, Matsui M, Suzuki S, Shibayama K, Doi M, Irie F, Yamato S, Otomo Y, Oishi K Tags: Jpn J Infect Dis Source Type: research

Detection of Enteric Viruses in Fecal Specimens from Nonbacterial Foodborne Gastroenteritis Outbreaks in Tokyo, Japan between 1966 and 1983.
Abstract We investigated the prevalence of five enteric viruses (norovirus [NoV], sapovirus [SAV], rotavirus, astrovirus, and adenovirus) in archived stool specimens collected from 70 foodborne gastroenteritis outbreaks in Tokyo, Japan that occurred from 1966 to 1983 and genetically characterized these viruses. NoV was detected in 48 (68.6%) outbreaks, while SaV, group C rotavirus (RVC), and astrovirus were detected in one (1.4%) outbreak each. Based on the partial capsid sequences, the detected NoVs were classified as the following genotypes: nine genogroup I (GI; GI.1-6, GI.8, GI.9, and GI.NA), 13 GII (GII.1-9, ...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Mori K, Nagano M, Kimoto K, Somura Y, Akiba T, Hayashi Y, Sadamasu K, Kai A Tags: Jpn J Infect Dis Source Type: research

The Epidemic of HIV, HCV and Syphilis and the Correlates of Sexual Transmitted Infections among Men Who Have Sex with Men in Zhenjiang, Jiangsu, China.
Abstract To investigate the epidemic of HIV, HCV and syphilis, HIV-1 subtype among men who have sex with men (MSM) and to measure factors that correlated with sexual transmitted infections (STIs), a cross-sectional survey was conducted among 657 MSM in Zhenjiang, Jiangsu, during 2012-2013. Social-demographic characterization and risky behaviors were collected and blood samples were obtained. In this survey, the prevalence of STIs of HIV (5.3%), HCV (0.6%) and syphilis (19.2%) were measured. Of 35 HIV-infected MSM, 1 (0.2%) and 17 (2.6%) were co-infected with HCV and syphilis. Among 33 samples with available HIV-1 ...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Shen L, Liu X, Fu GF, Hao S, Zhang M, Wang T, Yang J, Wu X, Mao L Tags: Jpn J Infect Dis Source Type: research

Immunity to diphtheria and tetanus in Army personnel and adult civilians in Mashhad, Iran.
This study aimed to determine serologic immunity to diphtheria and tetanus in army personnel and a sample of adult civilians in Mashhad, Iran. Army personnel (n=180) and civilians (n=83) of whom presented at Mashhad army hospital participated in this study. Diphtheria and tetanus antitoxins levels were determined by enzyme-linked immunosorbent assay. About 77% and 94% of army personnel aged 18-34 years had at least basic protection to diphtheria (antitoxin level ≥0.1 IU/ml) and tetanus (antitoxin level>0.1 IU/ml), respectively. For civilians of this age group, these proportions were 76% for both diseases. Antitoxins ...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Hosseini Shokouh SJ, Mohammadi B, Rajabi J, Mohammadian Roshan G Tags: Jpn J Infect Dis Source Type: research

HIV testing in Non-Injection Drug Users: prevalence and associated factors.
CONCLUSION: The determinants for HIV testing must be taken into account when planning prevention and programming strategies, including the widening of testing coverage among NIDU, educational health actions, links between sexually transmitted infections prevention services and addiction treatment services and the use of rapid tests to help people that are in contact with the virus learn about their HIV status, enter treatment, and improve their quality of life. PMID: 27357979 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Guimarães RA, Lucchese R, Fernandes IL, Vera I, Rodovalho AG, Guimarães VA, Silva GC, de Felipe RL, de Castro PA, Ferreira PM Tags: Jpn J Infect Dis Source Type: research

Genetic analysis of HIV-1 in Japan: A comprehensive analysis of donated blood.
CONCLUSIONS: Analysis of phylogenic trees suggested that the local outbreaks have become smaller in Japan; however, intermixing of viral types between these two areas was more evident in the more recent samples. PMID: 27357980 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Matsumoto C, Shinohara N, Sobata R, Uchida S, Satake M, Tadokoro K Tags: Jpn J Infect Dis Source Type: research

Characteristics of Multidrug-resistant Corynebacterium spp. Isolated from Blood Cultures from Hospitalized Patients in Japan.
We reported the epidemiological investigation of Corynebacterium spp. isolated from bloodstream specimens in Kurume University Hospital, between June 2008 and July 2011. Twenty-two Corynebacterium spp. likely isolates were isolated from 22 hospitalized patients, of which 12 (54.5%) strains were identified as Corynebacterium striatum. Minimum inhibitory concentration tests were performed after biochemical and genotypic identifications. Biofilm productions were detected using a 96-well microplate assay. The dissemination of Corynebacterium striatum was investigated by pulsed-field gel electrophoresis. All strains showed a te...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Qin L, Sakai Y, Bao R, Xie H, Masunaga K, Miura M, Hashimoto K, Tanamachi C, Hu B, Watanabe H Tags: Jpn J Infect Dis Source Type: research

Canine echinococcosis due to Echinococcus multilocularis: a second notifiable case from mainland Japan.
PMID: 27357982 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Morishima Y, Tomaru Y, Fukumoto SI, Sugiyama H, Yamasaki H, Hashimoto C, Harada K Tags: Jpn J Infect Dis Source Type: research

Development of a novel Loop-Mediated Isothermal Amplification (LAMP) assay for Rickettsia spp.
Abstract We developed a novel loop-mediated isothermal amplification (LAMP) detection method for Rickettsia spp., including Rickettsia prowazekii and Rickettsia typhi. Species-specific LAMP primers were developed for orthologous genes conserved among Rickettsia spp. The selected modified primers could detect all the Rickettsia spp. tested. Thus, the LAMP method was successfully used to detect 100 DNA copies of Rickettsia spp. within approximately 60 min at 63°C. This method may be an excellent tool for the early diagnosis of rickettsiosis in laboratory or in the field. PMID: 27357983 [PubMed - as supplied...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Hanaoka N, Matsutani M, Satoh M, Ogawa M, Shirai M, Ando S Tags: Jpn J Infect Dis Source Type: research

Histopathologic findings of lung with A/H1N1pdm09 infection-associated ARDS in the post-pandemic season.
In conclusion, pathological and molecular biological examinations revealed that an A/H1N1pdm09 infection-associated ARDS case in the post-pandemic season was not caused by direct alveolar epithelial damage due to viral infection, but rather by indirect damage of endothelial cells due to severe sepsis. PMID: 27357984 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Hayashi K, Yoshida H, Sato Y, Tobiume M, Suzuki Y, Ariyoshi K, Hasegawa H, Nakajima N Tags: Jpn J Infect Dis Source Type: research

High antiretroviral coverage and viral suppression prevalence in Japan: an excellent profile for downstream HIV care spectrum.
Abstract To understand the effectiveness of Japan's health care system for HIV/AIDS, including prevention, diagnosis, access to antiretroviral treatment, and treatment outcomes, clinical information on HIV/AIDS cases was collected through questioners sent to 377 registered HIV/AIDS clinics in Japan. The data were collected in 2009 and 2014, and 9,040 and 14,569 cases were obtained, respectively. Prevalence of on-treatment cases linked to care were 69.6% and 87.8% in 2009 and 2014, respectively, demonstrating improvement in treatment coverage over the recent 5 years. The proportion of cases with undetectable HIV RN...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Miyazaki N, Sugiura W, Gatanaga H, Watanabe D, Yamamoto Y, Yokomaku Y, Yoshimura K, Matsushita S, Japanese HIV-MDR Study Group Tags: Jpn J Infect Dis Source Type: research

Accuracy of stick-type kit and enzyme-linked immunosorbent assay for the detection of urinary Helicobacter pylori antibodies in a population of Japan Sea region of northern Japan.
Abstract In Japan, both a novel stick-type kit and ELISA kit are available for detection of antibody to Helicobacter pylori (H. pylori) in urine. However, the accuracy of these tests has not been fully examined in northern Japanese populations. Urine samples from 359 subjects were tested using a novel stick-type urinary H. pylori-antibody detection kit (RAPIRUN), while samples from 200 subjects were tested using an ELISA-based test (URINELISA). Prevalence of H. pylori infection was tested by (13)C-urea breath test (UBT) and a monoclonal antibody-based stool antigen test (TPAg). Subjects were considered to have the...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Shimoyama T, Sawada Y, Sawada N, Chinda D, Fukuda S Tags: Jpn J Infect Dis Source Type: research

The first case report of cerebral cyst infection due to Helicobacter cinaedi.
We report the first case of cerebral cyst infection of H. cinaedi, a fastidious spiral-shaped gram-negative rod bacterium.A 70-year-old man visited our hospital with a fever persisting for 2 weeks. He had received surgery and radiotherapy for parapharyngeal space squamous cell carcinoma 10 years ago. The radiotherapy had resulted in a cerebral cyst as a side effect, and an Ommaya reservoir had been inserted into the cyst. Blood culture and analysis of the brain cyst fluid revealed the presence of spiral-shaped gram-negative rod bacteria, which were identified as Helicobacter cinaedi by polymerase chain reaction.We first ad...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Abiko S, Nakamura I, Yamaguchi Y, Ohkusu K, Hirayama Y, Matsumoto T Tags: Jpn J Infect Dis Source Type: research

Bacteremia due to Arthrobacter creatinolyticus in an elderly diabetic man with acute cholangitis.
Abstract Arthrobacter species are gram-positive, aerobic, catalase-positive, coryneform bacteria belonging to the family Microbacteriaceae. An 87-year-old man with poorly controlled diabetic mellitus presented with fever, bedsores, and elevated hepatobiliary enzyme levels. He was diagnosed with bacteremia due to coryneform gram-positive bacilli with acute cholangitis. Doripenem and subsquencial sulbactum/ampicillin treatment were used for acute cholangitis, and the bacteremia was treated with 2 weeks of vancomycin treatment. The bacteremia was misidentified by phenotyping assay (API Coryne test), but was identifie...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Yamamoto K, Hayakawa K, Nagamatsu M, Fujiya Y, Mawatari M, Kutsuna S, Takeshita N, Tamura S, Mezaki K, Ohmagari N Tags: Jpn J Infect Dis Source Type: research

Elevated serum thymic stromal lymphopoietin found in wheezing children infected with human metapneumovirus.
This study was conducted to study the epidemiology and clinical manifestations of human metapneumovirus (hMPV) infection in children in the Suzhou area, China, and to investigate the effect of thymic stromal lymphopoietin (TSLP) on wheezing in hMPV-infected children. The study comprised 13 533 children with respiratory tract infection admitted to Children's Hospital of Soochow University between January 2009 and December 2014. Clinical data was recorded. The plasma levels of TSLP, IL4, and IL2 in 35 wheezing children with single hMPV infection and 15 non-wheezy children with hMPV infection and 35 wheezing children w...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Gu W, Wang Y, Hao C, Zhang X, Yan Y, Chen Z, Jiang W, Shao X, Ji W Tags: Jpn J Infect Dis Source Type: research

Regional Variations in the Incidence of Rotavirus Hospitalizations between Children Living in Defined regions of Akita and Kyoto Prefectures, Japan.
This study aimed at determining the incidence rates of rotavirus hospitalizations among children age
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Noguchi A, Ito H, Miura S, Fujii Y, Katayama K, Nakagomi T, Nakagomi O, Takahashi T Tags: Jpn J Infect Dis Source Type: research

Immune Response to Mumps Virus in Iranian Unvaccinated Young Adults.
Abstract Although first mumps vaccine was licensed many years ago, mumps vaccine added to Iran's Expanded Program on Immunization in 2003. Therefore, majority of Iranian young adults born before 2003 are unvaccinated and their immunity resulted of natural infection. For evaluation of cellular responses against mumps virus following natural infection, we investigated ninety Iranian unvaccinated young adults aged 20-30 years. Mumps specific memory CD4+ and CD8+ proliferation and frequency of cytotoxic lymphocyte CD8+ CD107a were evaluated using sensitive technique of flowcytometery. Our results showed thirty three o...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Keshavarz M, Shafiee A, Nicknam MH, Khosravani P, Yousefi A, Izad M Tags: Jpn J Infect Dis Source Type: research

HeLa-ACE2-TMPRSS2 cells are useful for the isolation of Human Coronavirus 229E.
PMID: 27357992 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Matoba Y, Aoki Y, Tanaka S, Yahagi K, Katsushima Y, Katsushima F, Sugawara K, Matsuzaki Y, Mizuta K Tags: Jpn J Infect Dis Source Type: research

An imported-case of scrub typhus from South Korea to Yamagata, Japan.
PMID: 27357993 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Suzuki Y, Shimanuki M, Seto J, Yahagi K, Mizuta K Tags: Jpn J Infect Dis Source Type: research

Co-colonization with Neisseria species is a risk factor for prolonged colonization with multidrug-resistant Acinetobacter baumannii in the respiratory tract.
Abstract Multidrug-resistant Acinetobacter baumannii (MDRAB) colonization increases the risk of spread in the hospital setting. The impact of clinical factors, including antibiotic use, on prolongation of MDRAB colonization has not been investigated. All patients with respiratory tract MDRAB based on culture were enrolled. Long-term colonizers and short-term colonizers were defined as patients whose colonization periods were>30 days or ≤30 days, respectively. Clinical data were abstracted from medical records. MDRAB were isolated in 34 patients. There were 13 long-term colonizers and nine short-term colonize...
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Kitazawa T, Seo K, Yoshino Y, Koga I, Ota Y Tags: Jpn J Infect Dis Source Type: research

A Novel Isolation of Mycoplasma amphoriforme from a Pediatric Patient with Protracted Bronchitis in Japan.
PMID: 27357995 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - June 30, 2016 Category: Infectious Diseases Authors: Katsukawa C, Asai S, Mizutani K, Arai K, Kohdera U, Kushibiki C, Shiomi M, Takeda Y, Naka A, Nakano K, Matsushita T, Takahashi K Tags: Jpn J Infect Dis Source Type: research

Intranasal Inactivated Influenza Vaccines: a Reasonable Approach to Improve the Efficacy of Influenza Vaccine?
Abstract Influenza is a contagious, acute respiratory disease caused by the influenza virus. The mucosal lining in the host respiratory tract is not only the site of virus infection, but also the site of defense; it is at this site that the host immune response targets the virus and protects against reinfection. One of the most effective methods to prevent influenza is to induce specific antibody (Ab) responses in the respiratory tract by vaccination. Two types of influenza vaccines, intranasal live attenuated influenza virus (LAIV) vaccines and parenteral (injectable) inactivated vaccines, are currently used worl...
Source: Japanese Journal of Infectious Diseases - May 25, 2016 Category: Infectious Diseases Authors: Tamura S, Ainai A, Suzuki T, Kurata T, Hasegawa H Tags: Jpn J Infect Dis Source Type: research

Geo-Demography of HIV/AIDS in Japan from 1985 to 2011: Incidence and Transmission Mode under Influence of Population Size/Density.
Abstract Volume 69, no. 2, p. 97-108, 2016. Page 107, Figure 11 should appear as shown below. PMID: 27212585 [PubMed - in process] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - May 25, 2016 Category: Infectious Diseases Authors: Yoshikura H Tags: Jpn J Infect Dis Source Type: research

Verification of the Overestimation of the "Deaths Associated with Influenza Pandemic of 1918-1919, Japan" Claimed in a Demographic Study.
Verification of the Overestimation of the "Deaths Associated with Influenza Pandemic of 1918-1919, Japan" Claimed in a Demographic Study. Jpn J Infect Dis. 2016;69(1):12-7 Authors: Nishimura H, Ohkusa Y Abstract Official records show that the Japanese influenza death toll in 1918-1920 was 385 thousand. However, a recently published study claims that the records are skeptical, claiming the figure to be "an anomaly by Asian standard," and re-estimated the number to be about 2 million by its unique demographical calculation. However, it is not sound from the following socio-historical...
Source: Japanese Journal of Infectious Diseases - May 20, 2016 Category: Infectious Diseases Authors: Nishimura H, Ohkusa Y Tags: Jpn J Infect Dis Source Type: research

Cryptococcosis in anti-interferon-gamma autoantibodies-positive patients: a different clinical manifestation from HIV-infected patients.
Abstract Disseminated nontuberculous mycobacterial (NTM) infection is the most common feature in patients positive for anti-interferon-gamma autoantibodies (IFN-γ Ab). Cryptococcus co-infects these patients. A retrospective, matched case-control study was conducted at Srinagarind Hospital between 1992 and 2013. We reviewed the charts of non-HIV-infected patients with cryptococcosis with disseminated NTM (case) and matched 2 HIV-infected patients (control) with cryptococcosis for each case. There were 16 cases and 32 controls. Among the 10 of 16 cased patients whose sera were available for testing, all were p...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Chetchotisakd P, Anunnatsiri S, Nithichanon A, Lertmemongkolchai G Tags: Jpn J Infect Dis Source Type: research

Severe Fever with Thrombocytopenia Syndrome Virus antibody investigation among domestic bovine transported to slaughterhouse in Shimane Prefecture, Japan.
PMID: 27169939 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Tabara K, Fujita H, Hirata A, Hayasaka D Tags: Jpn J Infect Dis Source Type: research

Streptozotocin-induced hyperglycaemic mice are susceptible to invasive enteric bacterial infection.
Abstract Diabetes mellitus and diarrhoea are increasingly becoming a global burden especially in developing countries like India. Diabetic patients are observed to be susceptible to the pathogenic bacteria particularly invasive enteric bacterial infection. Our study was designed on changes in pathophysiological parameters observed in streptozotocin-induced hyperglycaemic mice. In our experiments we infected streptozotocin treated hyperglycemic mice and control mice with different enteric pathogenic bacteria: non-typhoidal Salmonella, Shigella and Vibrio parahaemolyticus. Morbidity, mortality and bacterial load wer...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Koley H, Ghosh P, Sinha R, Mitra S, Mukherjee P, Howlader DR, Chaki C, Nag D Tags: Jpn J Infect Dis Source Type: research

Multi-typing of enterobacteria harboring lt and st enterotoxin genes isolated from mexican children.
MULTI-TYPING OF ENTEROBACTERIA HARBORING LT AND ST ENTEROTOXIN GENES ISOLATED FROM MEXICAN CHILDREN. Jpn J Infect Dis. 2016 May 9; Authors: Vázquez-Marrufo G, Rosales-Castillo JA, Robinson-Fuentes VA, Tafolla-Muñoz I, Carreras-Villaseñor N, Vázquez-Garcidueñas MS Abstract ETEC is the most common cause of diarrhea in children under 5 years from developing world. We used the sequencing of the 16S rRNA gene, the Biolog® system, and the Amplified Ribosomal DNA Restriction Analysis (ARDRA), to identify 69 Enterobacteria isolated from feces of healthy children up to 12...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Vázquez-Marrufo G, Rosales-Castillo JA, Robinson-Fuentes VA, Tafolla-Muñoz I, Carreras-Villaseñor N, Vázquez-Garcidueñas MS Tags: Jpn J Infect Dis Source Type: research

Serum from Nipah virus patients recognises recombinant viral proteins produced in Escherichia coli.
Abstract The genes for Nipah virus (NiV) N, F and G proteins were amplified from viral RNA, cloned into the plasmid pTriEx-3 Hygro, expressed and purified using immobilized metal affinity chromatography. The recombinant NiV proteins, rNiV-N, rNiV-F and rNiV-G, were successfully expressed in E. coli and purified with a yield of 4mg/L, 16mg/L and 4mg/L, respectively. All three recombinant viral proteins reacted with all 19 NiV-positive human sera with rNiV-N and rNiV-G being more immunogenic. The recombinant viral proteins did not react with any of the 12 NiV-negative sera. Serum from a case of late-onset relapsing ...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Tiong V, Lam CW, Phoon WH, AbuBakar S, Chang LY Tags: Jpn J Infect Dis Source Type: research

Epidemiological and clinical characteristics of patients with Middle East Respiratory syndrome Coronavirus in Iran in 2014.
In conclusion, we insist that all patients with acute respiratory symptoms, who had contact with a person that had recently traveled to Saudi-Arabia and experienced respiratory infection, should be investigated for MERS-CoV. PMID: 27169943 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Yousefi M, Dehesh MM, Farokhnia M Tags: Jpn J Infect Dis Source Type: research

The IL4-VNTR P1 allele, IL4-VNTR P2P2 genotype and IL4-VNTR_IL6-174CG P2P1-GG genotype are susceptable with a increased risk in Brucelosis.
This study aimed to investigate the association of IL-4, IL-6 and Macrophage migration inhibitory factor (MIF) polymorphisms and the susceptibility to Brucellosis. Consecutive adult patients with no known treatment against Brucellosis (n=120, Group I, ) who had no any other autoimmune and/or chronic disorders were included for the study. Age and sex matched controls who had no other autoimmune and/or chronic disorders were (n=120, healthy volunteers, Group II) selected as well. IL4_P2P2 genotype, IL4_P1 allele and IL4_VNTR-IL6_174CG compound genotype were frequent in the patient group compared to control subject and there ...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Gunal O, Yigit S, Yalcın AD, Celik B, Barut S, Demir O, Ates O, Duygu F, Kaya S, Rustemoglu A, Sezer O Tags: Jpn J Infect Dis Source Type: research

Clinical Presentation and Care for Patients with Ebola Virus Disease in China Ebola Treatment Unit, Liberia.
Abstract To clear the clinical characteristics of the confirmed Ebola Virus Disease (EVD) patients admitted to China Ebola Treatment Unit (China ETU) from January 2015 to March 2015, we retrospectively analyzed the clinical symptoms, treatments, and epidemiologic features of 5 patients with confirmed EVD, and reviewed literatures. We found that three survived and two died, the intervals from the onset of the symptoms to negative PCR test for Ebola virus in the three survivors were 14~18 days. Direct contact with confirmed patients within 21 days before admission were reported by three. All the patients had fever, ...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Shao X, Ren W, Zhou F Tags: Jpn J Infect Dis Source Type: research

Prevalence of M Protein Gene in Group C and Group G Streptococci Isolated from Patients in Thailand.
Abstract We surveyed the rate of M protein that was encoded by emm and emmL [emm (-like)] genes in group C and group G beta-hemolytic streptococci (GCS/GGS), as well as the rate of antimicrobial susceptibility. A total of 97 isolates [GCS/GGS (79) and other groups (18)] were tested for M protein gene by polymerase chain reaction. Focusing on invasive infections with group A beta-hemolytic streptococci (GAS), GCS, and GGS (isolated from blood), M protein gene was found in 90%, 84.6% and 78.3%, respectively. DNA sequencing in hypervariable N terminal region of emm gene was performed in 62 isolates. The results found...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Srifuengfung S, Tribuddharat C, Sapcharoen S, Nitayanon P Tags: Jpn J Infect Dis Source Type: research

Evaluation of five polymerase chain reaction (PCR) assays in diagnosis of Shiga toxin 2f -producing Escherichia coli.
PMID: 27169947 [PubMed - as supplied by publisher] (Source: Japanese Journal of Infectious Diseases)
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Koochakzadeh A, Badouei MA Tags: Jpn J Infect Dis Source Type: research

Scale-Free Distribution of Local Infection Cluster Sizes of Measles, Rubella, Syphilis and HIV/AIDS: Correlation with Size Distribution of Municipality Population That Was Also Scale-Free.
Abstract The size distribution of the local infection cluster (LIC), a group of patients reported from the same prefecture without interruption in successive weeks, was scale-free for infections that are transmitted from person to person (e.g., measles, rubella, syphilis and HIV/AIDS). For infections that never spread from person to person, the distribution was entirely random. The size distribution for measles, rubella, syphilis and HIV/AIDS could be simulated successfully by random coin tossing with probabilities that were higher for highly populated prefectures.The size distribution of the population in the lar...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Yoshikura H, Takeuchi F Tags: Jpn J Infect Dis Source Type: research

Argonaute 2 Suppresses the Infection of Japanese Encephalitis Virus in Aedes aegypti.
Abstract There are mainly three innate immunity mechanisms against viruses in mosquitoes. Infection by the flavivirus dengue virus is controlled by RNAi, the JAK-STAT, and Toll signaling pathways. Our studies of another flavivirus, Japanese encephalitis virus (JEV), showed that the virus was not highly infectious for the salivary glands of Aedes aegypti and that viral resistance may be mediated by innate immunity. Argonaute 2 (Ago2) plays a critical role in the RNA interference (RNAi) pathway. To further determine the mechanism of viral resistance, we focused on Ago2 as a potential target of JEV. We show here that...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Sasaki T, Kuwata R, Hoshino K, Isawa H, Sawabe K, Kobayashi M Tags: Jpn J Infect Dis Source Type: research

Seroprevalence of Crimean-Congo hemorrhagic fever in Turkey's Van Province.
This study aims to determine seroprevalence of CCHF in Turkey's Van province by analysis of blood samples obtained from people living in Van province. Blood specimens were taken from healthy people living in Van province and a variety of its villages between January 2012 and July 2012. Blood samples were initially tested by using a CCHF virus (CCHFV) IgM IgG kit for anti-CCHFV IgG followed by anti-CCHFV IgM determination of IgG positive blood samples. IgM-positive specimens were re-confirmed by Real Time-PCR. 107 men and 261 women were included in the study. 53 blood specimens (14.4%) were anti-CCHFV IgG positive, 2 of whi...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Bayram Y, Parlak M, Özkaçmaz A, Çıkman A, Güdücüoğlu H, Kılıç S, Berktaş M, Andac CA Tags: Jpn J Infect Dis Source Type: research

Peritoneal dialysis related peritonitis caused by Microbacterium paraoxydans.
Abstract A 54-year-old woman on continuous ambulatory peritoneal dialysis was admitted, complaining of diffuse abdominal pain. At peritoneal fluid cell count analysis, WBC count was 2990 cells/mm(3), with being neutrophil count 2510 cells/mm(3). She was treated empirically with intraperitoneal cefazolin and ceftazidime. After 6 days, Microbacterium species grew on peritoneal dialysate culture which had been taken on the day of admission. We analyzed 16S ribosomal RNA gene nucleotide sequence and identified it as M. paraoxydans. Based on the results of the antibiotics susceptibility test, the patient was treated wi...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Choi HS, Bae EH, Ma SK, Kim SW Tags: Jpn J Infect Dis Source Type: research

Four sporadic pediatric cases of Yersinia enterocolitica O:8 infection in rural area of Japan.
Abstract In the spring of 2015, we experienced a cluster of four sporadic Yersiniosis of children in Nagano prefecture, rural area of Japan. Two patients had developed appendicitis-like episodes, one had acute gastroenteritis, and the other one had bacteremia associated with liver abscess. Causative agent of these infections was Yersinia enterocolitica serogroup O:8. None of the patients had underlying illness, and all had recovered completely. The patients had no relationship between each other, neither socially nor geographically. These four consecutive cases suggest that Y. enterocolitica O:8 had spread substan...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Minami K, Yasuda R, Terakawa R, Koike Y, Takeuchi K, Higuchi T, Horiuchi A, Kubota N, Hidaka E, Kawakami Y Tags: Jpn J Infect Dis Source Type: research

High prevalence of diarrheagenic Escherichia coli among children with diarrhea in Kenya.
Abstract Diarrheagenic Escherichia coli (DEC) is an important agent of endemic and epidemic diarrhea worldwide, particularly in developing countries. DEC cannot be differentiated from the commensal E. coli on selective media with few exceptions. Most studies based on colony isolation method, which cannot detect presence of low numbers of DEC, might underestimate the incidence of DEC. In the present study, we employed colony sweep method with real-time PCR targeting virulence genes of 5 categories of DEC, which can detect very low numbers of DEC among hundreds of commensal E. coli. DEC was detected in 171 (55.9%) o...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Iijima Y, Oundo JO, Hibino T, Saidi SM, Hinenoya A, Osawa K, Shirakawa T, Osawa R, Yamasaki S Tags: Jpn J Infect Dis Source Type: research

Whole genome sequencing-based molecular epidemiologic analysis of autochthonous dengue virus type 1 strains circulating in Japan in 2014.
Abstract Cases of autochthonous dengue virus type 1 (DENV-1) infections were detected in Japan following a 70-year period devoid of dengue outbreaks. We have previously shown that E gene sequences are identical in 11 of 12 DENV-1 strains autochthonous to Japan. However, the E sequence represents only 14% of the genome. In the present study, we sequenced the entire genome of 6 autochthonous DENV-1 strains isolated from patients during the 2014 outbreak. Sequencing of 5 Yoyogi group strains with identical E sequences and 1 Shizuoka strain with a different E sequence revealed that the first Yoyogi group strain identi...
Source: Japanese Journal of Infectious Diseases - May 9, 2016 Category: Infectious Diseases Authors: Tajima S, Nakayama E, Kotaki A, Moi ML, Ikeda M, Yagasaki K, Saito Y, Shibasaki KI, Saijo M, Takasaki T Tags: Jpn J Infect Dis Source Type: research

Detection and molecular typing of human adenovirus associated with respiratory illness in Kerala.
Abstract Adenoviruses are responsible for approximately 5-10% of acute respiratory infections globally. However, there are limited reports on circulating respiratory human adenovirus (HAdV) types in India. We detected HAdV in the post mortem specimens of a young child died due to acute febrile illness. In order to know the circulating adenovirus types in the Alappuzha region, retrospectively, the samples (n=235) collected from influenza-like illness patients for influenza surveillance program were screened for HAdV. Fourteen samples were positive for adenovirus by PCR. Adenovirus was isolated from three out of fou...
Source: Japanese Journal of Infectious Diseases - March 18, 2016 Category: Infectious Diseases Authors: Thounaojam AD, Balakrishnan A, Mun AB Tags: Jpn J Infect Dis Source Type: research

Ureaplasma urealyticum: thepresence among sexually transmitted diseases.
UREAPLASMA UREALYTICUM: THEPRESENCE AMONG SEXUALLY TRANSMITTED DISEASES. Jpn J Infect Dis. 2016 Mar 18; Authors: Esen B, Gozalan A, Sevindi DF, Demirbas A, Onde U, Erkayıran U, Karakoc AE, Hasçiçek AM, Ergün Y, Adiloglu AK Abstract The study was aimed to detect Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Ureaplasma urealyticum, Mycoplasma hominis, and Trichomonas vaginalis in genital samples of symptomatic patients and to remark the presence of U.urealyticum infections in lower genital tract. Cervical and urethral samples from 96 patients (46 males, 50 fema...
Source: Japanese Journal of Infectious Diseases - March 18, 2016 Category: Infectious Diseases Authors: Esen B, Gozalan A, Sevindi DF, Demirbas A, Onde U, Erkayıran U, Karakoc AE, Hasçiçek AM, Ergün Y, Adiloglu AK Tags: Jpn J Infect Dis Source Type: research

High Rates of Hepatitis B, Hepatitis C and Human Immunodeficiency Virus (HBV, HCV, HIV) Infections and Their Uncommon HBV Genotype/Subtype and HCV Subtype Distributions among Transgender Individuals in Surabaya, Indonesia.
Abstract Transgender people are at high risk of sexually transmitted viruses such as hepatitis B virus (HBV) and human immunodeficiency virus (HIV). Moreover, Indonesia has a moderate to high rate of HBV infection and a rapid epidemic growth of HIV. Because hepatitis C virus (HCV) can co-occur with HBV and HIV, it was also evaluated in this study. Ten of 107 individuals (9.3%) were Hepatitis B surface antigen (HBsAg) positive and/or HBV DNA positive, whereas nineteen of 101 individuals (18.8%) with negative HBsAg were Hepatitis B core antibody (anti-HBc)-positive. Seven of 107 individuals (6.5%) were anti-HCV posi...
Source: Japanese Journal of Infectious Diseases - March 18, 2016 Category: Infectious Diseases Authors: Hadikusumo AA, Utsumi T, Amin M, Khairunisa SQ, Istimagfirah A, Wahyuni RM, Lusida MI, Soetjipto, Rianto E, Juniastuti, Hayashi Y Tags: Jpn J Infect Dis Source Type: research

Presepsin levels of patients with crimean-congo hemorrhagic fever.
PRESEPSIN LEVELS OF PATIENTS WITH CRIMEAN-CONGO HEMORRHAGIC FEVER. Jpn J Infect Dis. 2016 Mar 18; Authors: Demirpençe Ö, Doğan HO, Erşan S, Şahin M, Şahin H, Bakır M Abstract The presepsin level (a soluble CD14 subtype) is thought to increase in cases of bacterial infection. It has been stated that CD 14 also plays a role in the pathogenesis of various viral diseases. Crimean-Congo Hemorrhagic Fever (CCHF) is an arboviral zoonotic infection. Our study focuses on the presepsin level as a biomarker for CCHF. Serum presepsin levels in CCHF group (n=59) and control (n=28) have been compar...
Source: Japanese Journal of Infectious Diseases - March 18, 2016 Category: Infectious Diseases Authors: Demirpençe Ö, Doğan HO, Erşan S, Şahin M, Şahin H, Bakır M Tags: Jpn J Infect Dis Source Type: research

Effects of 1,25-dihydroxyvitamin D3 on Macrophage Cytokine Secretion Stimulated by Porphyromonas gingivalis.
Abstract Vitamin D has been known to be closely associated with periodontitis while the exact mechanisms remain to be clarified. The present study aimed to investigate the influence of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) on porphyromonas gingivalis (Pg)-stimulated cytokine production by macrophages and the involved signaling pathways. The main observation was that 1,25(OH)2D3 inhibited Pg-induced IL-6 cytokine expression while improved the expression of anti-inflammatory cytokine IL-10. Further analyses showed that 1,25(OH)2D3 decreased the p38 MAPK and ERK1/2 phosphorylation. Inhibited phosphorylation of p38 M...
Source: Japanese Journal of Infectious Diseases - March 18, 2016 Category: Infectious Diseases Authors: Xu QA, Li ZF, Zhang P, Cao LH, Fan MW Tags: Jpn J Infect Dis Source Type: research