Discrepancies in preferences regarding the care of terminal-phase pneumonia in elderly patients among patients, families, and doctors: A multicenter questionnaire survey in nagasaki, Japan
Publication date: Available online 3 July 2020Source: Respiratory InvestigationAuthor(s): Takahiro Takazono, Yoshifumi Imamura, Kaoru Kawakami, Naoya Yamasaki, Hiroyoshi Shimizu, Katsuhiro Usuki, Maiko Kiyohara, Tatsuro Hirayama, Masato Tashiro, Naoki Hosogaya, Tomomi Saijo, Kazuko Yamamoto, Taiga Miyazaki, Katsunori Yanagihara, Koichi Izumikawa, Hiroshi Mukae (Source: Respiratory Investigation)
Source: Respiratory Investigation - July 4, 2020 Category: Respiratory Medicine Source Type: research

Intractable diffuse pulmonary diseases: Manual for diagnosis and treatment
Publication date: Available online 2 July 2020Source: Respiratory InvestigationAuthor(s): Sakae Homma, Masahito Ebina, Kazuyoshi Kuwano, Hisatsugu Goto, Fumikazu Sakai, Susumu Sakamoto, Takeshi Johkoh, Keishi Sugino, Teruo Tachibana, Yasahiro Terasaki, Yasuhiko Nishioka, Koichi Hagiwara, Naozumi Hashimoto, Yoshinori Hasegawa, Akira Hebisawa, On behalf of the Ministry of Health, Labour and Welfare, the Study Group on Diffuse Pulmonary Disorders, Scientific Research/Research on Intractable Diseases, and Japanese Respiratory Society (Source: Respiratory Investigation)
Source: Respiratory Investigation - July 3, 2020 Category: Respiratory Medicine Source Type: research

A retrospective observational study of the treatment of a nosocomial infection caused by oseltamivir-resistant influenza virus A with baloxavir marboxil
Publication date: Available online 27 June 2020Source: Respiratory InvestigationAuthor(s): Miyako Fujita, Hirotsugu Matsumoto, Yasuo Inafuku, Jun Toyama, Jiro Fujita (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 28, 2020 Category: Respiratory Medicine Source Type: research

Trends in clinical features of novel coronavirus disease (COVID-19): A systematic review and meta-analysis of studies published from December 2019 to February 2020
Publication date: Available online 28 June 2020Source: Respiratory InvestigationAuthor(s): Toshie Manabe, Hiroyasu Akatsu, Kazuhiko Kotani, Koichiro Kudo (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 28, 2020 Category: Respiratory Medicine Source Type: research

COVID-19: Role of Neutrophil Extracellular Traps in Acute Lung Injury
Publication date: Available online 26 June 2020Source: Respiratory InvestigationAuthor(s): Ahmed Yaqinuddin, Peter Kvietys, Junaid Kashir (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 28, 2020 Category: Respiratory Medicine Source Type: research

Immortalized normal human lung epithelial cell models for studying lung cancer biology
Publication date: Available online 22 June 2020Source: Respiratory InvestigationAuthor(s): Mitsuo Sato, Jerry W. Shay, John D. Minna (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 22, 2020 Category: Respiratory Medicine Source Type: research

A case of intrapulmonary lymphangioma surrounded by pulmonary hilar structures
Publication date: Available online 20 June 2020Source: Respiratory InvestigationAuthor(s): Yusuke Muranishi, Nobutake Tanaka, Tomoya Kono, Ryo Miyahara (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 22, 2020 Category: Respiratory Medicine Source Type: research

Editorial Board
Publication date: July 2020Source: Respiratory Investigation, Volume 58, Issue 4Author(s): (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 18, 2020 Category: Respiratory Medicine Source Type: research

Idiopathic pulmonary fibrosis: Molecular mechanisms and potential treatment approaches
Publication date: Available online 30 May 2020Source: Respiratory InvestigationAuthor(s): Daniel S. Glass, David Grossfeld, Heather A. Renna, Priya Agarwala, Peter Spiegler, Lora J. Kasselman, Amy D. Glass, Joshua DeLeon, Allison B. Reiss (Source: Respiratory Investigation)
Source: Respiratory Investigation - June 1, 2020 Category: Respiratory Medicine Source Type: research

Histological differences between sarcoidosis and lung cancer-related sarcoid reaction
Publication date: Available online 29 May 2020Source: Respiratory InvestigationAuthor(s): Yoshiaki Kinoshita, Hiroshi Ishii, Yoshinobu Eishi, Keisuke Uchida, Masayo Yoshimura, Akinori Iwasaki, Masaki Fujita, Kazuki Nabeshima, Kentaro Watanabe (Source: Respiratory Investigation)
Source: Respiratory Investigation - May 30, 2020 Category: Respiratory Medicine Source Type: research

A new therapy for systemic sclerosis-associated interstitial lung disease
Publication date: Available online 22 May 2020Source: Respiratory InvestigationAuthor(s): Yasuhiro Kondoh (Source: Respiratory Investigation)
Source: Respiratory Investigation - May 23, 2020 Category: Respiratory Medicine Source Type: research

Outcomes and predictive factors for successful smoking cessation therapy in COPD patients with nicotine dependence
Publication date: Available online 4 May 2020Source: Respiratory InvestigationAuthor(s): Rika Hashimoto, Hiromi Tomioka, Takamasa Wada, Yuko Yoshizumi (Source: Respiratory Investigation)
Source: Respiratory Investigation - May 6, 2020 Category: Respiratory Medicine Source Type: research

Editorial Board
Publication date: May 2020Source: Respiratory Investigation, Volume 58, Issue 3Author(s): (Source: Respiratory Investigation)
Source: Respiratory Investigation - May 2, 2020 Category: Respiratory Medicine Source Type: research

Nintedanib inhibits epithelial-mesenchymal transition in A549 alveolar epithelial cells through regulation of the TGF-β/Smad pathway
Publication date: Available online 29 April 2020Source: Respiratory InvestigationAuthor(s): Hiroaki Ihara, Yoichiro Mitsuishi, Motoyasu Kato, Fumiyuki Takahashi, Ken Tajima, Takuo Hayashi, Moulid Hidayat, Wira Winardi, Aditya Wirawan, Daisuke Hayakawa, Koichiro Kanamori, Naohisa Matsumoto, Toshifumi Yae, Tadashi Sato, Shinichi Sasaki, Kazuya Takamochi, Yoshiyuki Suehara, Dai Ogura, Shin-ichiro Niwa, Kenji Suzuki (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 30, 2020 Category: Respiratory Medicine Source Type: research

COVID-19 outbreak: an elusive enemy
Publication date: Available online 17 April 2020Source: Respiratory InvestigationAuthor(s): Toshiaki Kikuchi (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 18, 2020 Category: Respiratory Medicine Source Type: research

MicroRNAs in pulmonary sarcoidosis: A systematic review
Publication date: Available online 15 April 2020Source: Respiratory InvestigationAuthor(s): Bijay Pattnaik, P.B. Sryma, Saurabh Mittal, Anurag Agrawal, Randeep Guleria, Karan Madan (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 17, 2020 Category: Respiratory Medicine Source Type: research

Comparison of different transbronchial biopsy sampling techniques for the diagnosis of peripheral pulmonary lesions with radial endobronchial ultrasound-guided bronchoscopy: A prospective study
Publication date: Available online 11 April 2020Source: Respiratory InvestigationAuthor(s): Viboon Boonsarngsuk, Tananchai Petnak, Apichart So-ngern, Bancha Saksitthichok, Wasana Kanoksil (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 11, 2020 Category: Respiratory Medicine Source Type: research

Chronic lung disease-associated PH: PAH-approved drugs and established universal healthcare insurance in Japan
Publication date: Available online 9 April 2020Source: Respiratory InvestigationAuthor(s): Seiichiro Sakao (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 11, 2020 Category: Respiratory Medicine Source Type: research

Characteristics and prognosis of interstitial pneumonias complicated with pneumomediastinum
Publication date: Available online 8 April 2020Source: Respiratory InvestigationAuthor(s): Shojiro Minomo, Toru Arai, Hisao Higo, Taisuke Tsuji, Kazunobu Tachibana, Masanori Akira, Yoshikazu Inoue (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 9, 2020 Category: Respiratory Medicine Source Type: research

Is unclassifiable idiopathic interstitial pneumonia a result of idiopathic pleuroparenchymal fibroelastosis?
Publication date: Available online 8 April 2020Source: Respiratory InvestigationAuthor(s): Hiroyoshi Yamauchi, Masashi Bando, Aya Shinozaki-Ushiku, Takashi Ogura, Tamiko Takemura, Masaaki Sato, Koichi Hagiwara (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 9, 2020 Category: Respiratory Medicine Source Type: research

Histology is critical but not always for the diagnosis of chronic hypersensitivity pneumonitis
Publication date: Available online 4 April 2020Source: Respiratory InvestigationAuthor(s): Yoshiaki Zaizen, Kazuhiro Tabata, Yasuhiko Yamano, Akira Hebisawa, Kensuke Kataoka, Andrey Bychkov, Takeshi Johkoh, Yasuhiro Kondoh, Junya Fukuoka (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 5, 2020 Category: Respiratory Medicine Source Type: research

Diagnostic usefulness of transbronchial lung cryobiopsy in two patients mildly affected with pulmonary lymphangioleiomyomatosis
Publication date: Available online 4 April 2020Source: Respiratory InvestigationAuthor(s): Mina Yoshida, Nobuyasu Awano, Minoru Inomata, Naoyuki Kuse, Mari Tone, Hanako Yoshimura, Tatsunori Jo, Kohei Takada, Toshio Kumasaka, Takehiro Izumo (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 5, 2020 Category: Respiratory Medicine Source Type: research

Comparison of ultrathin bronchoscopy with conventional bronchoscopy for the diagnosis of peripheral lung lesions without virtual bronchial navigation
Publication date: Available online 1 April 2020Source: Respiratory InvestigationAuthor(s): Toshiyuki Sumi, Takumi Ikeda, Takeyuki Sawai, Naoki Shijubou, Kenichi Kure, Yuichi Yamada, Hisashi Nakata, Yuji Mori, Hiroki Takahashi (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 2, 2020 Category: Respiratory Medicine Source Type: research

Role of serum periostin in the management of asthma and its comorbidities
Publication date: Available online 20 March 2020Source: Respiratory InvestigationAuthor(s): Hisako Matsumoto (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 21, 2020 Category: Respiratory Medicine Source Type: research

Predictors of acute exacerbation in biopsy-proven idiopathic pulmonary fibrosis
Publication date: Available online 20 March 2020Source: Respiratory InvestigationAuthor(s): Tomoo Kishaba, Hironao Hozumi, Tomoyuki Fujisawa, Yuichiro Nei, Noriyuki Enomoto, Hiroaki Sugiura, Masashi Kitani, Takafumi Suda (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 21, 2020 Category: Respiratory Medicine Source Type: research

Approach to management of chronic cough and chronic airway diseases: “Treatable traits” or correct diagnosis?
Publication date: Available online 19 March 2020Source: Respiratory InvestigationAuthor(s): Hisako Matsumoto (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 20, 2020 Category: Respiratory Medicine Source Type: research

Corynebacterium species as one of the major causative pathogens of bacterial pneumonia
Publication date: Available online 14 March 2020Source: Respiratory InvestigationAuthor(s): Kazuhiro Yatera, Hiroshi Mukae (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 15, 2020 Category: Respiratory Medicine Source Type: research

Comparison of chest computed tomography findings in nontuberculous mycobacterial diseases and Mycobacterium tuberculosis lung disease
Publication date: Available online 13 March 2020Source: Respiratory InvestigationAuthor(s): Jiro Fujita (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 15, 2020 Category: Respiratory Medicine Source Type: research

Evaluation of endobronchial volatile sulfur compounds for rapid diagnosis of lung abscesses caused by obligate anaerobes using Oral Chroma™: A pilot study
Publication date: Available online 12 March 2020Source: Respiratory InvestigationAuthor(s): Takahiro Takazono, Yoshifumi Imamura, Masayasu Kitamura, Reiko Furugen, Tatsuro Hirayama, Masato Tashiro, Tomomi Saijo, Kazuko Yamamoto, Taiga Miyazaki, Toshiyuki Saito, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 12, 2020 Category: Respiratory Medicine Source Type: research

Pulse oximetry saturation can predict prognosis of idiopathic pulmonary fibrosis
Publication date: Available online 8 March 2020Source: Respiratory InvestigationAuthor(s): Reoto Takei, Yasuhiko Yamano, Kensuke Kataoka, Toshiki Yokoyama, Toshiaki Matsuda, Tomoki Kimura, Taiki Furukawa, Osamu Takahashi, Hirofumi Chiba, Hiroki Takahashi, Yasuhiro Kondoh (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 9, 2020 Category: Respiratory Medicine Source Type: research

Resecting a giant malignant lung tumor in a patient with unilateral acute interstitial pneumonitis
Publication date: Available online 7 March 2020Source: Respiratory InvestigationAuthor(s): Hiroshi Yabuki, Muneo Minowa, Yuma Adachi, Yasuka Hara, Hiroshi Katsumata, Yoshifumi Matsuura (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 8, 2020 Category: Respiratory Medicine Source Type: research

Ability of high-resolution computed tomography to distinguish Mycoplasma pneumoniae pneumonia from other bacterial pneumonia: Significance of lateral bronchial lesions, less air bronchogram, and no peripheral predominance
Publication date: Available online 5 March 2020Source: Respiratory InvestigationAuthor(s): Masanori Nakanishi, Kiyoshi Nakashima, Masafumi Takeshita, Takeo Yagi, Tadashi Nakayama, Takao Kiguchi, Hiroki Yamada (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 5, 2020 Category: Respiratory Medicine Source Type: research

Pulmonary tuberculosis misdiagnosed as extensively drug-resistant tuberculosis due to selection of a nontuberculous mycobacterial colony from a preculture dish used for a drug-susceptibility test
Publication date: Available online 1 March 2020Source: Respiratory InvestigationAuthor(s): Reina Ohji, Tsutomu Shinohara, Hiroshi Ohji, Nobuo Hatakeyama, Sachiko Iwamura, Fumitaka Ogushi (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 2, 2020 Category: Respiratory Medicine Source Type: research

Editorial Board
Publication date: March 2020Source: Respiratory Investigation, Volume 58, Issue 2Author(s): (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 1, 2020 Category: Respiratory Medicine Source Type: research

Appreciation to Reviewers in 2019
Publication date: March 2020Source: Respiratory Investigation, Volume 58, Issue 2Author(s): (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 1, 2020 Category: Respiratory Medicine Source Type: research

Analysis of bronchoalveolar lavage samples collected from 30 patients with drug-induced pneumonitis
Publication date: Available online 26 February 2020Source: Respiratory InvestigationAuthor(s): Momoko Yamauchi, Shusaku Haranaga, Gretchen Parrott, Takeshi Kinjo, Tsuneo Yamashiro, Maho Tsubakimoto, Hiroshi Ohtsu, Shinichiro Ueda, Jiro Fujita (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 27, 2020 Category: Respiratory Medicine Source Type: research

The efficacy of carboplatin plus nanoparticle albumin-bound paclitaxel after cisplatin plus pemetrexed in non-squamous non-small-cell lung cancer patients
Publication date: Available online 26 February 2020Source: Respiratory InvestigationAuthor(s): Miho Tanaka, Tatsuya Ishii, Rie Tohnai, Shoichi Itoh, Yoshitaka Kawa, Yuko Kono, Yoshiko Urata, Yoshihiro Hattori, Miyako Satouchi (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 26, 2020 Category: Respiratory Medicine Source Type: research

Shorter corridors can be used for the six-minute walk test in subjects with chronic lung diseases
Publication date: Available online 26 February 2020Source: Respiratory InvestigationAuthor(s): Laura Gochicoa-Rangel, María C. Ramírez-José, Prysila Troncoso-Huitrón, Mónica Silva-Cerón, Carlos Guzmán-Valderrábano, Irma Lechuga-Trejo, Silvia Cid-Juárez, Luis Torre-Bouscoulet (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 26, 2020 Category: Respiratory Medicine Source Type: research

Pleural fluid lactate as a point-of-care adjunct diagnostic aid to distinguish tuberculous and complicated parapneumonic pleural effusions during initial thoracentesis: Potential use in a tuberculosis endemic setting
Publication date: Available online 24 February 2020Source: Respiratory InvestigationAuthor(s): Sze Shyang Kho, Swee Kim Chan, Mei Ching Yong, Hui Min Cheah, YC Gary Lee, Siew Teck Tie (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 25, 2020 Category: Respiratory Medicine Source Type: research

Comparison of the chest computed tomography findings between patients with pulmonary tuberculosis and those with Mycobacterium avium complex lung disease
ConclusionsChest CT findings would therefore be useful for distinguishing PTB and MACLD when typical findings are observed. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 24, 2020 Category: Respiratory Medicine Source Type: research

Deterioration of high-resolution computed tomography findings predicts disease progression after initial decline in forced vital capacity in idiopathic pulmonary fibrosis patients treated with pirfenidone
ConclusionsWe revealed that deterioration of HRCT findings may predict disease progression after the initial decline in %FVC in IPF patients treated with pirfenidone. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 24, 2020 Category: Respiratory Medicine Source Type: research

Inhibitory effects of glycopyrronium, formoterol, and budesonide on coronavirus HCoV-229E replication and cytokine production by primary cultures of human nasal and tracheal epithelial cells
ConclusionsThese findings suggest that glycopyrronium, formoterol, and a combination of glycopyrronium, formoterol, and budesonide inhibit HCoV-229E replication partly by inhibiting receptor expression and/or endosomal function and that these drugs modulate infection-induced inflammation in the airway. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 23, 2020 Category: Respiratory Medicine Source Type: research

Clinical, radiological, and pathological features of anti-asparaginyl tRNA synthetase antibody-related interstitial lung disease
ConclusionsMost KS-ILD patients showed a tendency for chronic disease onset and long-term stabilization of pulmonary function. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 23, 2020 Category: Respiratory Medicine Source Type: research

A superior vena cava aneurysm discovered by chance at regular physical examination
Publication date: Available online 20 February 2020Source: Respiratory InvestigationAuthor(s): Yasuhiro Nakajima, Toshiyuki Minami, Hirotoshi Ishigaki, Eirou Sakai, Ryo Takahashi, Takashi Yokoi, Kozo Kuribayashi, Takashi KijimaAbstractA superior vena cava (SVC) aneurysm is a rare disease that can be confused with upper mediastinal tumor. A 57-year-old female visited our hospital regarding an abnormal shadow in her mediastinum on a chest X-ray. Upon closer examinations, which included three-dimensional computed tomography, we diagnosed it as a SVC aneurysm. Since her SVC aneurysm was regarded as fusiform type at low risk of...
Source: Respiratory Investigation - February 21, 2020 Category: Respiratory Medicine Source Type: research

High prevalence of airway obstruction and pulmonary emphysema in urothelial (renal pelvis, ureter, and bladder) cancer patients
Publication date: Available online 20 February 2020Source: Respiratory InvestigationAuthor(s): Megumi Naka, Saki Shuto, Chisato Konishi, Koichi MaekawaAbstractBackgroundCigarette smoking is a major cause of COPD, with patients also presenting complications that stem from other smoking-related diseases, including urothelial cancer. However, the prevalence of COPD or airflow obstruction in urothelial cancer patients has not been well studied.MethodsWe investigated the prevalence of airflow obstruction (FEV1/FVC 
Source: Respiratory Investigation - February 20, 2020 Category: Respiratory Medicine Source Type: research

Lobar distribution of non-emphysematous gas trapping and lung hyperinflation in chronic obstructive pulmonary disease
ConclusionNon-emphysematous gas trapping in the upper and lower lobes has a distinct physiological effect, especially in COPD with minimal emphysema. This local evaluation might allow sensitive detection of changes in lung hyperinflation in COPD. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 19, 2020 Category: Respiratory Medicine Source Type: research

Clinical staging of idiopathic pulmonary fibrosis
Publication date: Available online 28 December 2019Source: Respiratory InvestigationAuthor(s): Tomoo Kishaba (Source: Respiratory Investigation)
Source: Respiratory Investigation - December 30, 2019 Category: Respiratory Medicine Source Type: research

Characteristics of 68 patients with clinically proven sarcoidosis based on the Japan Society of Sarcoidosis and Other Granulomatous Disorders 2015 criteria
ConclusionsThe age-specific distribution of clinically diagnosed sarcoidosis was similar to histologically diagnosed sarcoidosis in women, as previously reported. Rates of elevated serum lysozyme and sIL-2R levels were lower in this study than previously reported in histologically diagnosed patients in Japan. (Source: Respiratory Investigation)
Source: Respiratory Investigation - December 27, 2019 Category: Respiratory Medicine Source Type: research

Quantitative computed tomography measures of skeletal muscle mass in patients with idiopathic pulmonary fibrosis according to a multidisciplinary discussion diagnosis: A retrospective nationwide study in Japan
Publication date: Available online 24 December 2019Source: Respiratory InvestigationAuthor(s): Nobuyasu Awano, Minoru Inomata, Naoyuki Kuse, Mari Tone, Hanako Yoshimura, Tatsunori Jo, Kohei Takada, Chikatoshi Sugimoto, Tomonori Tanaka, Hiromitsu Sumikawa, Yuzo Suzuki, Tomoyuki Fujisawa, Takafumi Suda, Takehiro IzumoAbstractBackgroundIdiopathic pulmonary fibrosis (IPF) is a progressive disease often accompanied by skeletal muscle wasting. We investigated whether skeletal muscle mass and muscle attenuation on computed tomography (CT) are predictors of mortality in IPF patients, using a nationwide cloud-based database and web...
Source: Respiratory Investigation - December 25, 2019 Category: Respiratory Medicine Source Type: research

Editorial Board
Publication date: January 2020Source: Respiratory Investigation, Volume 58, Issue 1Author(s): (Source: Respiratory Investigation)
Source: Respiratory Investigation - December 24, 2019 Category: Respiratory Medicine Source Type: research