Are E-Cigarettes Safe? Here ’s What the Science Says

In 1965, when Herbert Gilbert was granted the first patent on a smoke- and tobacco-­free cigarette, he wrote that the product would “provide a safe and harmless means for and method of smoking.” More than 60 years later, however, modern iterations of Gilbert’s invention have sparked debate in the public-health community. E-cigarettes, which have grown increasingly popular in the past five years, were designed as a tool to help people quit ­smoking—and by doing so they should drastically reduce rates of lung cancer and other diseases. But the question is, does that potential outweigh their possible risks to human health? No easy answer Traditional cigarettes work by simple combustion: when tobacco is lit, it combines with oxygen and creates an inhalable smoke. E-cigarettes, sold by brands including Juul, Blu and Vuse, heat a chemical-­packed liquid that typically contains nicotine and often a flavoring agent, creating an aerosol. By delivering ­nicotine without tar and other nasty by-­products of combustion, e-cigarettes purportedly give smokers a healthier alternative to cigarettes while still satisfying cravings. It seems like a win-win. But in practice, there is no consensus yet about whether or not e-cigarettes effectively help smokers ditch cigarettes. Vapes, as they’re called, contain fewer of the cancer-­causing chemicals found in traditional cigarettes (like arsenic, benzene and formaldehyde), but there is little l...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized public health Source Type: news

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Authors: Cheng H, Chen Y, Li X, Chen F, Zhao J, Hu J, Shan A, Qiao S, Wei Z, He G, Xu B Abstract The mechanism underlying thrombosis in atrial fibrillation (AF) is not yet clearly understood. The apelin/APJ axis parallel and counter-regulate with the angiotensin system. The present study hypothesizes that apelin/APJ axis exert its anti-thrombus effect in normal left atrial tissue and is disrupted by up-regulated renin-angiotensin-aldosterone system (RAAS) signaling during AF. The specimens of left atrial appendages collected from patients with rheumatic mitral stenosis who underwent valve replacement were divided i...
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research
We present a 71-year-old Japanese man with metastasis prostate cancer that, during medical castration therapy, had torsades de pointes (TdP) with a QT prolongation and ventricular fibrillation (VF). His QT interval diminished after discontinuing the medical castration, and he developed no further VF recurrences for 15 months. Medical castration is a rare but possible trigger of TdP with QT prolongation and VF. PMID: 30518719 [PubMed - as supplied by publisher]
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research
DISCUSSION: In this case report, we are sharing our experience in management of this challenging case in view of the rarity of such peculiar clinical condition and the unfavourable presentation along with the lack of clear-cut Guideline and Consensus whether to/not to open such huge and immensely thrombosed symptomatic coronary artery fistula as well as the dilemma of choosing the best long-term medical treatment between antiplatelets vs anticoagulants in such young patient. PMID: 30520380 [PubMed - as supplied by publisher]
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
New research shows that cancer patients who are single receive less aggressive treatment than those who are married. NPR's Michel Martin talks with researcher Joan DelFattore about her findings.
Source: NPR Health and Science - Category: Consumer Health News Source Type: news
CONCLUSION: PUVA therapy is associated with an increased risk of CCNM inthe Mediterranean population. PMID: 30503067 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Authors: Gullón A, Sánchez Fuentes D, López-de-Sá E, Martí-Almor J, Barón-Esquivias G, Jiménez López J, Del Mar Contreras Muruaga M, Suárez Fernández C Abstract The present article provides an update on anticoagulant treatment in patients with atrial fibrillation in distinct clinical scenarios requiring particular considerations, such as ischaemic heart disease, electrical cardioversion, pulmonary vein ablation, the presence of valvular disease with or without prosthetic valves, and renal insufficiency, as well as old age and frailty. In patients...
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Publication date: Available online 8 December 2018Source: Results in PhysicsAuthor(s): B. Gowri Naidu, P. Sarita, G.J. Naga Raju, M.K. TiwariAbstractSynchrotron Radiation based X-ray fluorescence (SRXRF) technique was utilized for the determination of serum elemental profile in breast cancer patients group and healthy subjects group. The SRXRF experiments were performed on microprobe beamline-16, Indus-2 synchrotron radiation source at Raja Ramanna Centre for Advanced Technology (RRCAT), Indore, India. The accuracy and reliability of the experimental method were validated by using International Atomic Energy Agency (IAEA) ...
Source: Results in Physics - Category: Physics Source Type: research
Publication date: 1 March 2019Source: Colloids and Surfaces B: Biointerfaces, Volume 175Author(s): Jing Luo, Yang Cheng, Xiao-Yan He, Yi Liu, Na Peng, Zhi-Wei Gong, Kui Wu, Tao ZouAbstractTo realize efficiently cellular uptake and enhance the immunostimulation, thiolated cytosine-phosphate-guanine (CpG) oligodeoxynucleotides (ODNs) were self-assembled on hollow gold nanospheres (HGNs) to form CpG-HGNs. The cellular uptake of CpG-HGNs in immune cells was studied in RAW 264.7 cells. Due to the enhanced delivery efficiency, CpG-HGNs exhibited a higher immune stimulatory activity compared with CpG ODNs, resulting in a dramatic...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
ConclusionsThis series of patients undergoing PD with PG shows that the operation can be performed safely with excellent outcomes for a variety of malignant and benign conditions.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
ConclusionPreoperative and intraoperative factors can be used to predict probability of non-home discharge immediately after completion of pancreaticoduodenectomy.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
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