Two weeks to bowel cancer?
There’s no doubt antibiotics have saved a lot of lives. But because they’ve been overprescribed for so many years we’ve ended up with a slew of health problems. For one thing, overuse of antibiotics wreaks havoc on your microbiome… That’s your body’s ecosystem. Your microbiome has 100 trillion or so bacteria, viruses and fungi. It affects just about every organ and body system. Some of these gut bugs cause disease and infection. But other good bacteria are called “probiotics.” They boost your immune system. They help you digest your food and turn it into vitamins. But in your gut, antibiotics kill off good bacteria along with the bad. When that happens, your immune system gets weak. Your risk of obesity and heart disease goes up. So do rates of allergies, asthma, autism and autoimmune diseases.1 And now shocking new research says antibiotics can even spike your risk of bowel cancer. And it can happen in just two weeks! A study in the journal Gut looked at data from 16,000 women over 60 years old. They were part of the famous Nurses Health Study.2 Results showed that taking antibiotics increased their risk of getting adenomas or polyps. These are growths on the lining of the bowel that can become cancerous. Women who took antibiotics in their 20s and 30s for as little as 15 days to two months increased their risk by up to 36%. It was worse for those who took these drugs in their 40s and 50s for longer periods of time....
Conclusion: DV may be a useful biomarker for early prediction of therapeutic outcome in intermediate HCC. Published on 2018-04-20 13:58:11
"We all know certain dogs enjoy chewing things they shouldn't but managing to devour four full teddy bears is quite a feat," the dog's vet said
AbstractThe geriatric nutritional risk index (GNRI) is a simple and well-established nutritional assessment tool that is a significant prognostic factor for various cancers. However, the role of the GNRI in predicting clinical outcomes of diffuse large B cell lymphoma (DLBCL) patients has not been investigated. To address this issue, we retrospectively analyzed a total of 476 patients with newly diagnosed de novo DLBCL. We defined the best cutoff value of the GNRI as 96.8 using a receiver operating characteristic curve. Patients with a GNRI
AbstractRecent reports identify NLR (the ratio between absolute neutrophils counts, ANC, and absolute lymphocyte count, ALC), as predictor of progression-free survival (PFS) and overall survival (OS) in cancer patients. We retrospectively tested NLR and LMR (the ratio between absolute lymphocyte and monocyte counts) in newly diagnosed Hodgkin lymphoma (HL) patients treated upfront with a PET-2 risk-adapted strategy. NLR and LMR were calculated using records obtained from the complete blood count (CBC) from 180 newly diagnosed HL patients. PFS was evaluated accordingly to Kaplan-Meier method. Higher NLR was associated to ad...
The finding by Remmler et al1 that increased levels of interleukin 6 (IL6) predict 90-day and 1-year mortality in patients with end-stage liver disease is of high importance. In addition to its relevance for prognosis and timing of liver transplantation, we believe that the determination of IL6 levels could represent a pos sible target for therapy. Indeed, IL6 increases occur in autoimmune diseases, but more importantly is a consequence of infections. Viral causes of chronic liver diseases, such as hepatitis C and B viruses, now can be cured in a very high percentage of patients with the administration of antivirals.
CONCLUSION: Decreased SpO2 was a significant predictor of abnormal mitral Doppler flow. Diastolic dysfunction should be considered when SpO2 ≤ 95% is found. PMID: 29671629 [PubMed - as supplied by publisher]
CONCLUSIONS: D-FP21-PEG-PEI/plasmid DNA is a safe and efficient gene delivery vehicle for ovarian cancer targeted therapy. PMID: 29667478 [PubMed - in process]
Authors: Rafael D, Gener P, Andrade F, Seras-Franzoso J, Montero S, Fernández Y, Hidalgo M, Arango D, Sayós J, Florindo HF, Abasolo I, Schwartz S, Videira M Abstract Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the progressive gain of resistance of advanced cancers, new anticancer therapies should be validated specifically for this subpopulation of cells. A new amphihilic-based gene delivery system that ...
DISCUSSION: Five studies met the inclusion criteria and were included in the systematic review. The average Jadad score was 1, the average level of evidence 3. In two studies, infection and revision occured more often in obese patients. Patients with morbid obesity had a higher risk of wound revision and periprosthetic joint infections. Three studies showed that obese patients had significantly lower scores for clinical outcome measures in function and pain. The legal aspect was not discussed in any of the five studies. Overall, published data are sparse and very heterogeneous. Therefore comparing these five studies is dif...
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