5 Ways The Zika Virus Is Here To Stay
Zika virus’ status as a global health threat may officially be over, but the disease’s impact is far from contained. The World Health Organization decided in November to end its designation of Zika virus as a public health emergency, but that doesn’t mean that Zika virus has disappeared, explained Dr. Carlos Pardo-Villamizar, a clinical neurologist with an expertise in infectious disorders at Johns Hopkins Medicine. Alongside pressing concerns about how to prevent a resurgence of the disease, health care systems in Brazil and other countries that saw births of babies infected with the disease in utero now have to find a way to fund and facilitate expensive, intensive therapy and care for thousands of children who have been born with birth defects. As the WHO itself acknowledged, the outbreak will remain a “significant public health challenge.” And regions of the world that dodged a large Zika virus outbreak in 2016 are still at risk for them in 2017, said Pardo-Villamizar, because the Aedes aegypti mosquito has not been eradicated. This includes other Central and South American countries that didn’t see many infections, countries in Asia that regularly experience dengue outbreaks and the southern region of the U.S. Dr. Thomas Frieden, director of the U.S. Centers for Disease Control and Prevention, says the U.S. still has a lot of work to do when it comes to controlling Zika virus, protecting pregnant women from the disease...
In this study, structural proteins of MERS-CoV were expressed in silkworm larvae and Bm5 cells for the development of vaccine candidates against MERS-CoV and diagnostic methods. The spike (S) protein of MERS-CoV lacking its transmembrane and cytoplasmic domains (SοTM) was secreted into the hemolymph of silkworm larvae using a bombyxin signal peptide and purified using affinity chromatography. The purified SοTM forms small nanoparticles as well as the full-length S protein and has the ability to bind human dipeptidyl peptidase 4 (DPP4), which is a receptor of MERS-CoV. These results indicate that bioactive S...
Publication date: November 2019Source: Fish &Shellfish Immunology, Volume 94Author(s): Jing Wang, Jia-Jia Du, Biao Jiang, Run-Zhen He, An-Xing LiAbstractShort-term feed deprivation or fasting is commonly experienced by aquaculture fish species and may be caused by seasonal variations, production strategies, or diseases. To assess the effects of fasting on the resistance of Nile tilapia to Streptococcus agalactiae infection, vaccinated and unvaccinated fish were fasted for zero, one, three, and seven days prior to infection. The cortisol levels of both vaccinated and unvaccinated fish first decreased and then increased ...
ConclusionsThis is the first randomised investigation of BP self-monitoring for the management of pregnancy hypertension and indicates that a large RCT would be feasible.
Publication date: Available online 12 October 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Shahin Khayambashi, Amber Salter, Tuula Tyry, Gary R Cutter, Robert J Fox, Ruth Ann MarrieAbstractObjectiveWe aimed to determine the association between gender identity and sexual orientation on healthcare-related utilization in persons with multiple sclerosis (MS), as well as satisfaction with their doctor and comfort discussing sexual health with their doctor.MethodsWe surveyed participants from the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry regarding their gender identity and sexua...
Publication date: Available online 12 October 2019Source: Journal of Hospital InfectionAuthor(s): Jaspreet Dhanda, James Gray, Ellen Knox, Amreen Bashir
In the original publication of this article , there are error in the Fig. 5, the “ml” should be replaced by “mL” (Fig. 5A) and “IFNγ” should be “IFN-γ” in Fig. 5A, B. The correct figure is below:
The article published in 2013  described the use of the availableBrachyspira multilocus sequence typing (MLST) scheme  to characterize the population structure of the intestinal spirocheteBrachyspira pilosicoli. It used sequences of seven loci that were amplified from 131 strains that had been isolated from different geographical origins and species.
Tubal reversal and pregnancy are possible after endometrial ablation. Dr. Monteith offers hope to women who want to ahve a baby after endometrial ablation. The post Can You Get Pregnant After Endometrial Ablation And Tubal Ligation? appeared first on A Personal Choice.
ConclusionsBronchodilator dose responsiveness may be useful for phenotyping and may be of utility in practice and future studies focused on asthma outcomes or quantification of treatment responses. In children and adolescents, this phenotype of poor bronchodilator responsiveness may be associated with periods of relatively stable disease yet marked airway constriction in response to triggers, including tobacco smoke, respiratory infections/pneumonia, and aeroallergens.
ConclusionWe applied the ALDEN score to the claims database to identify possible culprit drugs for SJS and TEN in South Korea. This approach could shed light on research and policymaking for drug adverse reactions.
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