Contraceptive pills not proven to protect against the flu

Conclusion These are interesting scientific findings but they have limited implications. Animal studies are useful for giving an indication of how biological processes may work in humans but we're not identical. Then the scenarios tested here – the progesterone, or the flu injection – can be taken as representative of real-life in humans. For one thing all the mice had surgery to remove their ovaries before being infected. It makes sense that the mice that had been given some additional recovery boost in the form of hormone replacement may have been in a better health state than those left hormone depleted. They were also directly inoculated through the nose with a flu dose that has previously been demonstrated to be lethal in these animals, and the animals did die. It's just those with progesterone survived about an extra two days. The findings do suggest the progesterone hormone may have various roles in female health – also here seeming to improve lung cellular repair. However, since most women have the progesterone hormone naturally in their bodies this doesn't mean a great deal. We can't leap to saying that women who take progestogen-containing contraception hormones have added protection against infection, or are less likely to get flu. This certainly hasn't been tested. To reduce your risk of getting flu or spreading it to other people, you should always: make sure you wash your hands regularly with soap and warm water clean surfaces such...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

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In this report we demonstrated, for the first time, that Mn2+ triggers regulated necrosis (RN) in BV-2 cells involving two central mechanisms: parthanatos and lysosomal disruption. The occurrence of parthanatos is supported by several cellular and molecular events: (i) DNA damage; (ii) AIF translocation from mitochondria to the nucleus; (iii) mitochondrial membrane permeabilization; and (iv) PARP1-dependent cell death. On the other hand, Mn2+ induces lysosomal membrane permeabilization (LMP) and cathepsin D (CatD) release into the cytosol supporting the lysosomal disruption. Pre-incubation with CatB and D inhibitors partia...
Source: Neuroscience - Category: Neuroscience Source Type: research
ConclusionsAlternative approaches for capturing the effects of weight status in the preschool years on preference-based HRQoL outcomes should be tested. The application of the QALY framework to economic evaluations of obesity-related interventions in young children should also consider longitudinal effects over the life-course.Clinical Trial Registration The Healthy Beginnings Trial was registered with the Australian Clinical Trial Registry (ACTRNO12607000168459).
Source: Quality of Life Research - Category: Health Management Source Type: research
Conclusions: NVI following KD is more common after lower energy-level mechanisms. Obesity is associated with NVI in lower energy-level mechanisms. Physicians should be vigilant in screening for NVI in the setting of KD even with seemingly benign mechanisms of injury, especially in patients with obesity. Level of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
Objectives: What patient characteristics and injury factors predict decreased knee range of motion (ROM) after operative management of tibial plateau fractures? Design: Prospective cohort study. Setting: Academic medical center. Patients: Over 11 years, tibial plateau fractures at a single academic institution were prospectively followed. A total of 266 patients were included in this study. Intervention: Surgical repair of tibial plateau fractures and secondary interventions due to arthrofibrosis. Main outcome measure: Clinical outcomes were evaluated using the Short Musculoskeletal Function Assessment and...
Source: Journal of Orthopaedic Trauma - Category: Orthopaedics Tags: Original Article Source Type: research
This article seeks to discuss health care disparities as well as health behaviors and outcomes in this population. In addition, it will review the appropriate recommendations for clinical care of sexual minority women for the obstetrician/gynecologist.
Source: Clinical Obstetrics and Gynecology - Category: OBGYN Tags: Caring for Lesbians, Bisexual Women, Transgender, and Gender Nonconforming People Source Type: research
Placenta accreta spectrum (PAS) refers to an abnormally invasive implantation of the placenta into the uterine myometrium. The resultant risk is that of severe maternal hemorrhage and significant maternal morbidity and even mortality. The 2 strongest risk factors for the development of PAS are a history of a prior cesarean section and a placenta previa in the current pregnancy. Clinically, most patients are asymptomatic but some will present with vaginal bleeding and abdominal cramping. The goal of this article is to discuss the common clinical presentation and risk factors for placenta accreta spectrum, and to review in d...
Source: Clinical Obstetrics and Gynecology - Category: OBGYN Tags: Management of Abnormal Placentation Source Type: research
No abstract available
Source: MCN: The American Journal of Maternal Child Nursing - Category: Nursing Tags: ONGOING COLUMNS: Hot Topics in Maternity Nursing Source Type: research
No abstract available
Source: MCN: The American Journal of Maternal Child Nursing - Category: Nursing Tags: ONGOING COLUMNS: Perinatal Patient Safety Source Type: research
Biolife4D has achieved a milestone in its ultimate quest to develop human organs for transplant. The company recently announced that it has developed a cardiac patch using a highly specialized 3D printer designed to protect living cells during the printing process. The patch is designed to help patients recover heart function after an acute myocardial infarction, said Ravi Birla, PhD, the company’s chief science officer, in an interview with MD+DI. “Over several weeks, acute myocardial infarction results in scar formation and progresses to chronic heart failure, severely damp...
Source: MDDI - Category: Medical Devices Authors: Tags: 3-D Printing Source Type: news
Authors: Tsuboi R, Matsumoto S, Miyatani H, Mashima H Abstract An 18-year-old man diagnosed with ileocolonic Crohn's disease with circumferential strictures of the ascending colon started treatment with mesalazine and subsequently underwent right hemicolectomy. After surgery, the patient was started on adalimumab, and the clinical course was favorable. Nine months postoperatively, colonoscopy revealed granular mucosa with circumferential and continuous involvement from the transverse colon down to the rectum, findings which resembled ulcerative colitis. Mesalazine allergy was suspected, and the inflammatory finding...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
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