Janssen Announces Unblinding of Phase 3 CARTITUDE-4 Study of CARVYKTI ® (cilta-cel) as Primary Endpoint Met in Treatment of Patients with Relapsed and Refractory Multiple Myeloma
RARITAN, New Jersey, January 27, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the Phase 3 CARTITUDE-4 study evaluating CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) versus pomalidomide, bortezomib, and dexamethasone (PVd) or daratumumab, pomalidomide, and dexamethasone (DPd) for the treatment of patients with relapsed and lenalidomide-refractory multiple myeloma met its primary endpoint of significant improvement in progression-free survival (PFS) at the first pre-specified interim analysis. As a result of meeting the primary endpoint, the Independent Data Monitoring Commi...
Source: Johnson and Johnson - January 27, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Probing Cough Syrup Deaths; COVID Vax Safety in Kids; Fatal Epidural Error
(MedPage Today) -- Note that some links may require subscriptions. The World Health Organization (WHO) issued an urgent call to action after at least seven countries have reported cases and three countries have reported more than 300 fatalities... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 24, 2023 Category: Infectious Diseases Source Type: news

WHO Urges'immediate Action' After Cough Syrup Deaths WHO Urges'immediate Action' After Cough Syrup Deaths
The World Health Organization has called for ' immediate and concerted action ' to protect children from contaminated medicines after a spate of child deaths linked to cough syrups last year.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 24, 2023 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Africa: WHO Calls for 'Immediate' Action After Cough Syrup Deaths
[DW] Contaminated cough syrups have been linked to hundreds of child deaths in Africa and Asia. The WHO is reportedly investigating potential connections between the pharmaceutical companies that made the products. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 24, 2023 Category: African Health Source Type: news

Expert tips to shake off this winter's hacking cough
ANGELA EPSTEIN: Persistent, hacking coughs seem to be the soundtrack to winter this year. (Source: the Mail online | Health)
Source: the Mail online | Health - January 24, 2023 Category: Consumer Health News Source Type: news

WHO investigating links among cough syrup deaths, considers advice for parents
Citing "unacceptable levels" of toxins in the products, the WHO is seeking more information about the specific raw materials used by six manufacturers in India and Indonesia to produce medicines linked to the recent deaths, as well as whether the companies obtained them from some of the same suppliers, the person said. The WHO has not named any suppliers. (Source: The Economic Times)
Source: The Economic Times - January 24, 2023 Category: Consumer Health News Source Type: news

NHS to roll-out new vaccine to tackle bronchiolitis-causing winter cough virus RSV
Children and vulnerable adults may soon receive a breakthrough vaccine to protect them from one a common winter bug after scientists announced the first step in vaccinating eligible Britons for RSV. (Source: the Mail online | Health)
Source: the Mail online | Health - January 21, 2023 Category: Consumer Health News Source Type: news

Nigeria: Nigeria Confirms Outbreak of New Infection, Records 25 Deaths
[Premium Times] NCDC listed symptoms of diphtheria to include fever, runny nose, sore throat, cough, red eyes (conjunctivitis) and neck swelling. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - January 20, 2023 Category: African Health Source Type: news

Moderna Says RSV Vaccine 84% Effective at Preventing Symptoms in Older Adults Moderna Says RSV Vaccine 84% Effective at Preventing Symptoms in Older Adults
Moderna said on Tuesday that its experimental mRNA vaccine for respiratory syncytial virus was 83.7% effective in a late-stage trial at preventing at least two symptoms, such as cough and fever, in adults aged 60 and older.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 18, 2023 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news

​​​​The Upcoming Lunar New Year Holiday Threatens a Grim COVID Toll in China
Harry Li is conflicted. Ideally, the law student wants to spend the Lunar New Year holiday in his home village in northern China’s Hebei province, but he is afraid of spending more than 12 hours on crowded trains and buses lest he brings COVID-19 to his elderly parents, who have not been vaccinated. “It’s been three years since I’ve been home [for Lunar New Year],” says Li, 20, who studies some 700 miles from home in Shanghai. “I was vaccinated nine months ago but everyone around me is still getting sick.” This week, millions of Chinese face a similar conundrum. Before the pandemic...
Source: TIME: Health - January 17, 2023 Category: Consumer Health News Authors: Charlie Campbell / Singapore Tags: Uncategorized China COVID-19 overnight Source Type: news

ANGELA EPSTEIN: What's behind the hacking cough that's making everyone feel so rotten?
ANGELA EPSTEIN: From Covid to flu and the nasty cold doing the rounds, it seems most people are currently battling a bug. (Source: the Mail online | Health)
Source: the Mail online | Health - January 16, 2023 Category: Consumer Health News Source Type: news

UCL launches clinical trial to test if cough medicine ambroxol can slow down Parkinson's disease
The drug, Ambroxol - which comes in both pill and syrup form - is already used to ease coughing by clearing away mucus in the lungs of patients with respiratory diseases. (Source: the Mail online | Health)
Source: the Mail online | Health - January 14, 2023 Category: Consumer Health News Source Type: news

Marion cough syrup not sold in any other country: WHO
On Wednesday, the UN health agency had said that Noida-based Marion Biotech's cough syrups AMBRONOL and DOK-1 Max are "substandard", and warned against their use, days after Uzbekistan claimed that 18 children had died after consuming the company's syrup. Following WHO's alert, Indian authorities have halted production at Marion Biotech. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - January 13, 2023 Category: Pharmaceuticals Source Type: news

'Probe into Marion Biotech's cough syrup finds gaps in testing'
They said information related to the excipients, such as drug licence, batch number and adherence to the standards laid down by the Indian or US pharmacopoeias is missing. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - January 13, 2023 Category: Pharmaceuticals Source Type: news

WHO warns against use of Marion Bio's two cough syrups
"Two cough syrups made by India's Marion Biotech should not be used for children after the products were linked to 19 deaths in Uzbekistan," the WHO said on Wednesday. The products are AMBRONOL syrup and DOK-1 Max syrup. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - January 12, 2023 Category: Pharmaceuticals Source Type: news