The cognitive effects of stopping and starting antipsychotics on changes in cognitive functioning
CONCLUSION: The results suggest that prescribers should consider discontinuance of an antipsychotic if the patient is reporting cognitive problems and their symptoms are manageable off the medications. The findings hope to spark future research into the effects of antipsychotic use on biomarkers of progressive dementias (e.g. Alzheimer's disease).PMID:38602221 | DOI:10.1080/13607863.2024.2336209 (Source: Aging and Mental Health)
Source: Aging and Mental Health - April 11, 2024 Category: Geriatrics Authors: Brian G Collin Source Type: research
Country-level sociocultural context and socioeconomic inequalities in adolescent dietary behaviours: A multilevel analysis in 21 European countries
This study examined whether the country-level sociocultural context and changes thereof were associated with adolescent socioeconomic inequalities in dietary behaviours. International comparative data of 344,352 adolescents living in 21 countries participating in 2002, 2006, 2010 and 2014 waves of the Health Behaviour in School-aged Children (HBSC) survey were combined with aggregated levels of openness-to-change from the European Social Survey (ESS). Four dietary behaviours (i.e., fruit, vegetable, sweets and soft drink consumption) and two measures of socioeconomic status (SES) on the individual level (i.e., family afflu...
Source: Appetite - April 11, 2024 Category: Nutrition Authors: Maxim Dierckens Benedicte Deforche Bart De Clercq Dominic Weinberg Gonneke W J M Stevens Angeline Chatelan Manon Rouche Els Clays Katrijn Delaruelle Source Type: research
A nonsynonymous mutation in BhLS, encoding an acyl-CoA N-acyltransferase leads to fruit and seed size variation in wax gourd (Benincasa hispida)
In this study, we observed a strong correlation between fruit size and seed size variation in our mapping population, indicating genetic control by a single gene, BhLS, with large size being dominant over small. Through bulk segregant analysis sequencing and fine mapping with a large F2 population, we precisely located the BhLS gene within a 47.098-kb physical interval on Chromosome 10. Within this interval, only one gene, Bhi10M000649, was identified, showing homology to Arabidopsis HOOKLESS1. A nonsynonymous mutation (G to C) in the second exon of Bhi10M000649 was found to be significantly associated with both fruit and ...
Source: TAG. Theoretical and Applied Genetics - April 11, 2024 Category: Genetics & Stem Cells Authors: Jinqiang Yan Jiaowen Cheng Dasen Xie Yi Wang Min Wang Songguang Yang Biao Jiang Lin Chen Jinsen Cai Wenrui Liu Source Type: research
The neuroprotective effects of Ferulic acid in toxin-induced models of Parkinson's disease: a review
Ageing Res Rev. 2024 Apr 9:102299. doi: 10.1016/j.arr.2024.102299. Online ahead of print.ABSTRACTParkinson's disease is predominantly caused by dopaminergic neuron loss in the substantia nigra pars compacta and the accumulation of alpha-synuclein protein. Though the general consensus is that several factors, such as aging, environmental factors, mitochondrial dysfunction, accumulations of neurotoxic alpha-synuclein, malfunctions of the lysosomal and proteasomal protein degradation systems, oxidative stress, and neuroinflammation, are involved in the neurodegeneration process of Parkinson's disease, the precise mechanism by...
Source: Ageing Research Reviews - April 11, 2024 Category: Genetics & Stem Cells Authors: Samira Hassani Abolghasem Esmaeili Source Type: research
The cognitive effects of stopping and starting antipsychotics on changes in cognitive functioning
CONCLUSION: The results suggest that prescribers should consider discontinuance of an antipsychotic if the patient is reporting cognitive problems and their symptoms are manageable off the medications. The findings hope to spark future research into the effects of antipsychotic use on biomarkers of progressive dementias (e.g. Alzheimer's disease).PMID:38602221 | DOI:10.1080/13607863.2024.2336209 (Source: Aging and Mental Health)
Source: Aging and Mental Health - April 11, 2024 Category: Geriatrics Authors: Brian G Collin Source Type: research
Country-level sociocultural context and socioeconomic inequalities in adolescent dietary behaviours: A multilevel analysis in 21 European countries
This study examined whether the country-level sociocultural context and changes thereof were associated with adolescent socioeconomic inequalities in dietary behaviours. International comparative data of 344,352 adolescents living in 21 countries participating in 2002, 2006, 2010 and 2014 waves of the Health Behaviour in School-aged Children (HBSC) survey were combined with aggregated levels of openness-to-change from the European Social Survey (ESS). Four dietary behaviours (i.e., fruit, vegetable, sweets and soft drink consumption) and two measures of socioeconomic status (SES) on the individual level (i.e., family afflu...
Source: Appetite - April 11, 2024 Category: Nutrition Authors: Maxim Dierckens Benedicte Deforche Bart De Clercq Dominic Weinberg Gonneke W J M Stevens Angeline Chatelan Manon Rouche Els Clays Katrijn Delaruelle Source Type: research
The neuroprotective effects of ferulic acid in toxin-induced models of Parkinson's disease: A review
Ageing Res Rev. 2024 Apr 9;97:102299. doi: 10.1016/j.arr.2024.102299. Online ahead of print.ABSTRACTParkinson's disease is predominantly caused by dopaminergic neuron loss in the substantia nigra pars compacta and the accumulation of alpha-synuclein protein. Though the general consensus is that several factors, such as aging, environmental factors, mitochondrial dysfunction, accumulations of neurotoxic alpha-synuclein, malfunctions of the lysosomal and proteasomal protein degradation systems, oxidative stress, and neuroinflammation, are involved in the neurodegeneration process of Parkinson's disease, the precise mechanism...
Source: Ageing Research Reviews - April 11, 2024 Category: Genetics & Stem Cells Authors: Samira Hassani Abolghasem Esmaeili Source Type: research
Nutritional Sources and Anticancer Potential of Phenethyl Isothiocyanate: Molecular Mechanisms and Therapeutic Insights
Phenethyl Isothiocyanate (PEITC) exhibits its anticancer potential by modulating key signaling pathways, enforcing cell cycle arrest, promoting apoptosis, and enhancing drug efficacy by overcoming multidrug resistance and influencing drug metabolism enzymes. AbstractPhenethyl isothiocyanate (PEITC), a compound derived from cruciferous vegetables, has garnered attention for its anticancer properties. This review synthesizes existing research on PEITC, focusing on its mechanisms of action in combatting cancer. PEITC has been found to be effective against various cancer types, such as breast, prostate, lung, colon, and pancre...
Source: Molecular Nutrition and Food Research - April 11, 2024 Category: Food Science Authors: Shahira M. Ezzat,
Rana M. Merghany,
Passent M. Abdel Baki,
Nariman Ali Abdelrahim,
Sohaila M. Osman,
Mohamed A. Salem,
Sheila I. Pe ña‐Corona,
Hernán Cortés,
Lashyn Kiyekbayeva,
Gerardo Leyva‐Gómez,
Javad Sharifi‐Rad,
Daniela Calina Tags: Review Source Type: research
Molecules, Vol. 29, Pages 1732: Effect of the Drying Method and Storage Conditions on the Quality and Content of Selected Bioactive Compounds of Green Legume Vegetables
This study aimed to determine the effect of the drying method (freeze-drying, air-drying), storage period (12 months), and storage conditions (2–4 °C, 18–22 °C) applied to two legume species: green beans and green peas. The raw and dried materials were determined for selected physical parameters typical of dried vegetables, contents of bioactive components (vitamin C and E, total chlorophyll, total carotenoids, β-carotene, and total polyphenols), antioxidative activity against the DPPH radical, and sensory attributes (overall quality and profiles of color, te...
Source: Molecules - April 11, 2024 Category: Chemistry Authors: Piotr G ębczyński Ma łgorzata Tabaszewska Katarzyna Kur Maria Zbylut-G órska Jacek S łupski Tags: Article Source Type: research
Sensors, Vol. 24, Pages 2467: Development of Multimodal Fusion Technology for Tomato Maturity Assessment
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Xiaohuan Guo
The maturity of fruits and vegetables such as tomatoes significantly impacts indicators of their quality, such as taste, nutritional value, and shelf life, making maturity determination vital in agricultural production and the food processing industry. Tomatoes mature from the inside out, leading to an uneven ripening process inside and outside, and these situations make it very challenging to judge their maturity with the help of a single modality. In this paper, we propose a deep learning-assisted multimodal data fusion technique combining color imaging, spectroscopy, and haptic sensing for the matu...
Source: Sensors - April 11, 2024 Category: Biotechnology Authors: Yang Liu Chaojie Wei Seung-Chul Yoon Xinzhi Ni Wei Wang Yizhe Liu Daren Wang Xiaorong Wang Xiaohuan Guo Tags: Article Source Type: research
Spectroscopic evaluation of sesame and mustard oils treated with Murchana method
This study focusses on the spectroscopic analysis of sesame and mustard oils prepared using the ayurvedic processing method ‘Murchana’. Spectroscopic analysis techniques including UV-Vis absorbance spectroscopy, fluorescence spectroscopy, and FTIR spectroscopy were employed to study the oils. Origin software was used to plot graphs of the spectra. The result s indicated that themurchana process may reduce the components of the oil responsible for its oxidation, thereby increasing the shelf life of the oils. However, further investigations, including other spectroscopy and chromatography techniques, will prove beneficia...
Source: Lasers in Medical Science - April 11, 2024 Category: Laser Surgery Source Type: research
Fruit and vegetable intake and risk of disabling dementia: JPHC Disabling Dementia Study
CONCLUSIONS: Fruit and vegetable intake and dietary intake of vitamin C may contribute to reducing the risk of disabling dementia among men and women.PMID:38599388 | DOI:10.1016/j.tjnut.2024.04.008 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Rie Kishida Kazumasa Yamagishi Hiroyasu Iso Junko Ishihara Nobufumi Yasuda Manami Inoue Shoichiro Tsugane Norie Sawada JPHC Study Group Source Type: research
A stable and flexible Au@Ag NPs/PVA SERS platform for thiram residue detection on rough surface
Talanta. 2024 Mar 27;274:126008. doi: 10.1016/j.talanta.2024.126008. Online ahead of print.ABSTRACTFlexible and transparent surface-enhanced Raman scattering (SERS) substrates have gained great attention in analysis field as they offer a fast, non-destructive, and highly sensitive platform for in-situ detection. In this work, we present a facile one-pot strategy for synthesizing gold-cored silver shell nanoparticles (Au@Ag NPs) in the polyvinyl alcohol (PVA) colloid. With no other reducing agents, PVA can serve as both reducing and stabilizing agents for forming Au@Ag NPs. Besides, PVA acts as a scaffold to maintain SERS "...
Source: Talanta - April 10, 2024 Category: Chemistry Authors: Tao Shao Jinsong Xu Hang Zhong Yi Hu Jun Chen Source Type: research
A stable and flexible Au@Ag NPs/PVA SERS platform for thiram residue detection on rough surface
Talanta. 2024 Mar 27;274:126008. doi: 10.1016/j.talanta.2024.126008. Online ahead of print.ABSTRACTFlexible and transparent surface-enhanced Raman scattering (SERS) substrates have gained great attention in analysis field as they offer a fast, non-destructive, and highly sensitive platform for in-situ detection. In this work, we present a facile one-pot strategy for synthesizing gold-cored silver shell nanoparticles (Au@Ag NPs) in the polyvinyl alcohol (PVA) colloid. With no other reducing agents, PVA can serve as both reducing and stabilizing agents for forming Au@Ag NPs. Besides, PVA acts as a scaffold to maintain SERS "...
Source: Talanta - April 10, 2024 Category: Chemistry Authors: Tao Shao Jinsong Xu Hang Zhong Yi Hu Jun Chen Source Type: research
Flavonoids in vegetables: improvement of dietary flavonoids by metabolic engineering to promote health
(Source: Critical Reviews in Food Science and Nutrition)
Source: Critical Reviews in Food Science and Nutrition - April 10, 2024 Category: Nutrition Authors: Tao, Han Li, Linying He, Yuqing Zhang, Xueying Zhao, Yao Wang, Qiaomei Hong, Gaojie Source Type: research
