Self-medication with herbal medicine and breast cancer survival: a prospective monocentric study
ConclusionThis study concluded that self-medication with Graviola or Alenda may be associated with an increase of death risk in patients with breast cancer. Further studies are needed to confirm these results. (Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - October 1, 2021 Category: Cancer & Oncology Source Type: research

Antiproliferation Activity and Apoptotic Mechanism of Soursop (Annona muricata L.) Leaves Extract and Fractions on MCF7 Breast Cancer Cells
(Source: Vascular Health and Risk Management)
Source: Vascular Health and Risk Management - July 15, 2021 Category: Cardiology Tags: Breast Cancer: Targets and Therapy Source Type: research

Integrated Ultrasound-Mechanical Stirrer Technique for Extraction of Total Alkaloid Content from Annona muricata
Publication date: Available online 8 July 2021Source: Process BiochemistryAuthor(s): Chia Hau Lee, Lee Ting Hun, Pei Ying Ong, Syie Luing Wong, Norfadilah Hamdan, Amal A.M. Elgharbawy, Nurul Alia Azmi (Source: Process Biochemistry)
Source: Process Biochemistry - July 9, 2021 Category: Biochemistry Source Type: research

Therapeutic Role of Annona muricata Fruit and Bee Venom Against MNU-Induced Breast Cancer in Pregnant Rats and its Complications on the Ovaries
(Source: Vascular Health and Risk Management)
Source: Vascular Health and Risk Management - July 8, 2021 Category: Cardiology Tags: Breast Cancer: Targets and Therapy Source Type: research

Chloroform Fraction of Methanolic Extract of Seeds of Annona muricata Induce S Phase Arrest and ROS Dependent Caspase Activated Mitochondria-Mediated Apoptosis in Triple-Negative Breast Cancer
(Source: Anti-Cancer Agents in Medicinal Chemistry)
Source: Anti-Cancer Agents in Medicinal Chemistry - June 24, 2021 Category: Cancer & Oncology Authors: Kariyil, Bibu J. Ayyappan, Usha P.T. Gopalakrishnan, Anu George, Ajith J. Tags: Research article Source Type: research

Soursop juice enhanced seminal antioxidant defence and semen quality of rabbit bucks in extremely dry climatic condition of Southwestern Nigeria
Publication date: Available online 17 June 2021Source: Journal of Thermal BiologyAuthor(s): Olatunji Abubakar Jimoh, Bolaji Fatai Oyeyemi, Wahab Adekunle Oyeyemi (Source: Journal of Thermal Biology)
Source: Journal of Thermal Biology - June 17, 2021 Category: Biology Source Type: research

Synergistic Cotreatment Potential of Soursop (Annona muricata L. ...
This study aims to unveil the anticancer activity of AME as a cotreatment agent with doxorubicin (dox) on 4T1 cells and AME’s relation to senescence. AME was obtained by maceration using 96% ethanol. AME was then subjected to qualitative analysis using TLC compared to quercetin (hRf = 75). Spectrophotometry analysis of AME resulted in a total flavonoid content of 2.3%± 0.05%. Cytotoxic evaluation using the MTT assay revealed that AME showed an IC50 value of 63µg/mL, while its combination (25µg/mL) with dox (10 nM) decreased the viability of 4T1 cells to 58 % (CI = 0.15). Flowcytometry using propidi...
Source: Iranian Journal of Pharmaceutical Research - May 31, 2021 Category: Drugs & Pharmacology Source Type: research

Molecules, Vol. 26, Pages 2861: α-Terpineol: An Aggregation Pheromone in Optatus palmaris (Coleoptera: Curculionidae) (Pascoe, 1889) Enhanced by Its Host-Plant Volatiles
-Abarca The Annonaceae fruits weevil (Optatus palmaris) causes high losses to the soursop production in Mexico. Damage occurs when larvae and adults feed on the fruits; however, there is limited research about control strategies against this pest. However, pheromones provide a high potential management scheme for this curculio. Thus, this research characterized the behavior and volatile production of O. palmaris in response to their feeding habits. Olfactometry assays established preference by weevils to volatiles produced by feeding males and soursop. The behavior observed suggests the presence of an aggregation pher...
Source: Molecules - May 12, 2021 Category: Chemistry Authors: Jos é Manuel Pineda-Ríos Juan Cibri án-Tovar Luis Mart ín Hernández-Fuentes Rosa Mar ía López-Romero Lauro Soto-Rojas Jes ús Romero-Nápoles Celina Llanderal-C ázares Luis F. Salom é-Abarca Tags: Article Source Type: research

In vitro studies of Annona muricata L. extract ‐loaded electrospun scaffolds for localized treatment of breast cancer
AbstractThis paper presents in vitro studies of the sustained release ofAnnona muricata leaf extracts (AME) from hybrid electrospun fibers for breast cancer treatment. Electrospun hybrid scaffolds were fabricated from crude AME extracts, poly(lactic ‐co‐glycolic acid)/gelatin (PLGA/Ge) and pluronic F127. The physicochemical properties of the AME extract and scaffolds were studied. The antiproliferative effects of the scaffolds were also assessed on breast cancer (MCF‐7 and MDA‐MB‐231) and non‐tumorigenic breast (MCF10A) cell lines. Scanning electron microscope micrographs revealed a random network of micro‐ a...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 7, 2021 Category: Materials Science Authors: Udom M. Akpan, Michael Pellegrini, Ali A. Salifu, John D. Obayemi, Theresa Ezenwafor, Daniel Browe, Chukwuemeka J. Ani, Yiporo Danyuo, Stella Dozie ‐Nwachukwu, Olushola S. Odusanya, Joseph Freeman, Winston O. Soboyejo Tags: RESEARCH ARTICLE Source Type: research

In vitro studies of Annona muricata L. extract-loaded electrospun scaffolds for localized treatment of breast cancer
J Biomed Mater Res B Appl Biomater. 2021 May 7. doi: 10.1002/jbm.b.34852. Online ahead of print.ABSTRACTThis paper presents in vitro studies of the sustained release of Annona muricata leaf extracts (AME) from hybrid electrospun fibers for breast cancer treatment. Electrospun hybrid scaffolds were fabricated from crude AME extracts, poly(lactic-co-glycolic acid)/gelatin (PLGA/Ge) and pluronic F127. The physicochemical properties of the AME extract and scaffolds were studied. The antiproliferative effects of the scaffolds were also assessed on breast cancer (MCF-7 and MDA-MB-231) and non-tumorigenic breast (MCF10A) cell lin...
Source: Biomed Res - May 7, 2021 Category: Research Authors: Udom M Akpan Michael Pellegrini Ali A Salifu John D Obayemi Theresa Ezenwafor Daniel Browe Chukwuemeka J Ani Yiporo Danyuo Stella Dozie-Nwachukwu Olushola S Odusanya Joseph Freeman Winston O Soboyejo Source Type: research

In vitro studies of Annona muricata L. extract-loaded electrospun scaffolds for localized treatment of breast cancer
J Biomed Mater Res B Appl Biomater. 2021 May 7. doi: 10.1002/jbm.b.34852. Online ahead of print.ABSTRACTThis paper presents in vitro studies of the sustained release of Annona muricata leaf extracts (AME) from hybrid electrospun fibers for breast cancer treatment. Electrospun hybrid scaffolds were fabricated from crude AME extracts, poly(lactic-co-glycolic acid)/gelatin (PLGA/Ge) and pluronic F127. The physicochemical properties of the AME extract and scaffolds were studied. The antiproliferative effects of the scaffolds were also assessed on breast cancer (MCF-7 and MDA-MB-231) and non-tumorigenic breast (MCF10A) cell lin...
Source: Biomed Res - May 7, 2021 Category: Research Authors: Udom M Akpan Michael Pellegrini Ali A Salifu John D Obayemi Theresa Ezenwafor Daniel Browe Chukwuemeka J Ani Yiporo Danyuo Stella Dozie-Nwachukwu Olushola S Odusanya Joseph Freeman Winston O Soboyejo Source Type: research

Self-medication with herbal medicine and breast cancer survival: a prospective monocentric study
CONCLUSION: This study concluded that self-medication with Graviola or Alenda may be associated with an increase of death risk in patients with breast cancer. Further studies are needed to confirm these results.PMID:33748880 | DOI:10.1007/s00432-021-03600-y (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - March 22, 2021 Category: Cancer & Oncology Authors: Wala Ben Kridis Ahmed Mnif Souhir Khmiri Nabil Toumi Afef Khanfir Source Type: research

Self-medication with herbal medicine and breast cancer survival: a prospective monocentric study
CONCLUSION: This study concluded that self-medication with Graviola or Alenda may be associated with an increase of death risk in patients with breast cancer. Further studies are needed to confirm these results.PMID:33748880 | DOI:10.1007/s00432-021-03600-y (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - March 22, 2021 Category: Cancer & Oncology Authors: Wala Ben Kridis Ahmed Mnif Souhir Khmiri Nabil Toumi Afef Khanfir Source Type: research

Study of parameters affecting the degradation of rhodamine-B and methyl orange dyes by Annona muricata leaf extract synthesized nanoparticles as well as their recyclability
Publication date: Available online 15 March 2021Source: Journal of Molecular StructureAuthor(s): Aditya Velidandi, Ninian Prem Prashanth Pabbathi, Rama Raju Baadhe (Source: Journal of Molecular Structure)
Source: Journal of Molecular Structure - March 16, 2021 Category: Molecular Biology Source Type: research

Anti-parasitic activity of Annona muricata L. leaf ethanolic extract and its fractions against Toxoplasma gondii in vitro and in vivo
Publication date: Available online 12 March 2021Source: Journal of EthnopharmacologyAuthor(s): Natália Carnevalli Miranda, Ester Cristina Borges Araujo, Allisson Benatti Justino, Yusmaris Cariaco, Caroline Martins Mota, Layane Alencar Costa-Nascimento, Foued Salmen Espindola, Neide Maria Silva (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - March 12, 2021 Category: Drugs & Pharmacology Source Type: research