Efficacy of Annona muricata (graviola) in experimental spinal cord injury: biochemical and histopathological analysis
CONCLUSION: Our histopathological and biochemical results showed that AM is an agent with neuroprotective effects in trau-matic SCI.PMID:35485570 | DOI:10.14744/tjtes.2021.70728 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - April 29, 2022 Category: Emergency Medicine Authors: Emrah Keskin Özlem Elmas Havva Hande Keser Şahin Berrak G üven Source Type: research
Phytochemical Constituents and Ameliorative Effect of the Essential Oil from Annona muricata L. Leaves in a Murine Model of Breast Cancer
This study concludes that the EOAm leaves showed an ameliorative effect in a murine model of breast cancer.PMID:35335182 | DOI:10.3390/molecules27061818 (Source: Cancer Control)
Source: Cancer Control - March 26, 2022 Category: Cancer & Oncology Authors: Juan Pedro Rojas-Armas Jorge Luis Arroyo-Acevedo Miriam Palomino-Pacheco Jos é Manuel Ortiz-Sánchez James Calva Hugo Jesus Justil-Guerrero Americo Castro-Luna Norma Ramos-Cevallos Edwin C ésar Cieza-Macedo Oscar Herrera-Calderon Source Type: research
Molecules, Vol. 27, Pages 1818: Phytochemical Constituents and Ameliorative Effect of the Essential Oil from Annona muricata L. Leaves in a Murine Model of Breast Cancer
This study concludes that the EOAm leaves showed an ameliorative effect in a murine model of breast cancer. (Source: Molecules)
Source: Molecules - March 10, 2022 Category: Chemistry Authors: Juan Pedro Rojas-Armas Jorge Luis Arroyo-Acevedo Miriam Palomino-Pacheco Jos é Manuel Ortiz-Sánchez James Calva Hugo Jesus Justil-Guerrero Americo Castro-Luna Norma Ramos-Cevallos Edwin C ésar Cieza-Macedo Oscar Herrera-Calderon Tags: Article Source Type: research
Molecules, Vol. 27, Pages 1201: Pharmacological Activities of Soursop (Annona muricata Lin.)
Hadisaputri
Soursop (Annona muricata Lin.) is a plant belonging to the Annonaceae family that has been widely used globally as a traditional medicine for many diseases. In this review, we discuss the traditional use, chemical content, and pharmacological activities of A.muricata. From 49 research articles that were obtained from 1981 to 2021, A.muricata’s activities were shown to include anticancer (25%), antiulcer (17%), antidiabetic (14%), antiprotozoal (10%), antidiarrhea (8%), antibacterial (8%), antiviral (8%), antihypertensive (6%), and wound healing (4%). Several biological activities and the gener...
Source: Molecules - February 10, 2022 Category: Chemistry Authors: Mutakin Mutakin Rizky Fauziati Fahrina Nur Fadhilah Ade Zuhrotun Riezki Amalia Yuni Elsa Hadisaputri Tags: Review Source Type: research
Annona muricata as Possible Alternative in the Treatment of Hyperglycemia: A Systematic Review
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - January 24, 2022 Category: Nutrition Authors: Patricia Mart ín del Campo-Rayas Elia Herminia Valdez Miramontes Zyanya Reyes Castillo Source Type: research
Effect of < em > Annona muricata < /em > Leaf Extract Towards the Sertoli Cells on Alloxan-Induced Mice
Conclusion:</b> The administration of <i>A. muricata</i> leaf extract during 14 days significantly reduced the number of Sertoli cells on alloxan-induced mice.PMID:34989208 | DOI:10.3923/pjbs.2021.1316.1321 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 6, 2022 Category: Biomedical Science Authors: Devi E Gugun Supri I Handayani None Lisnawati Budiana Tanuarja Siti Nurbaya Vivitri D Prasasty Nurhuda Sahar Source Type: research
Evaluation of the Modulatory Effect of < em > Annona muricata < /em > Extracts on the Activity of Some Selected Antibiotics against Biofilm-Forming MRSA
Evid Based Complement Alternat Med. 2021 Dec 20;2021:9342110. doi: 10.1155/2021/9342110. eCollection 2021.ABSTRACTThe study investigated the influence of Annona muricata extracts on the action of selected antibiotics against biofilm-forming MRSA. The various parts of the plant were processed into powder and extracted with ethanol or hot water and then screened for the presence of phytochemicals. The modulatory effect of the Annona muricata extract was also tested on some antibiotics against Methicillin-resistant Staphylococcus aureus (MRSA). The findings from this study revealed that the various parts of the Annona muricat...
Source: Evidence-based Complementary and Alternative Medicine - December 30, 2021 Category: Complementary Medicine Authors: David Neglo Clement Okraku Tettey Edward Ken Essuman Justice Dziedzorm Amenu Felix Charles Mills-Robertson Daniel Sedohia Adjoa Agyemang Boakye Daniel A Abaye Source Type: research
Molecules, Vol. 26, Pages 7675: Antitumor Potential of Annona muricata Linn. An Edible and Medicinal Plant in Mexico: In Vitro, In Vivo, and Toxicological Studies
In this study, ethanol extracts of Am collected in Acapulco and Tecpan from Guerrero state were evaluated orally on Balb/c mice inoculated with 4T1 cells, for cytotoxic activity (CA) on 4T1 cells, in brine shrimp lethality assay (BSLA), and for acute oral toxicity in mice. In addition, ethanol extracts were subjected to high-performance liquid chromatography (HPLC) with diode array detection. Results showed that the extracts collected in December in Acapulco (AcDe) and Tecpan (TeDe) exhibited the most significant antitumor and cytotoxic activity. In the BSLA, the most important effect was observed in the extracts from Acap...
Source: Molecules - December 18, 2021 Category: Chemistry Authors: Verenice Merl ín-Lucas Rosa Mar ía Ordoñez-Razo Fernando Calzada Aida Sol ís Normand Garc ía-Hernández Elizabeth Barbosa Miguel Vald és Tags: Article Source Type: research
Topic use of Annona crassiflora Mart. contributes to wound healing due to the antioxidant and proliferative effects of fibroblasts
Some plants species have secondary compounds with healing properties, many of which were used to start the development of new drugs for the pharmaceutical industry [1]. The family,Annonaceae, is recognized for its healing activity, with studies conducted on Annona reticulata, Annona muricata, and Annona squamosa [2 –4]. One of the species in this family is the A. crassiflora Mart. Plant parts such as bark, leaves, fruits, and seeds are widely used in folk medicine to treat inflammation and pain associated with rheumatism, wounds, venereal diseases, snakebites, and microbial infections [5,6]. (Source: Injury)
Source: Injury - December 7, 2021 Category: Orthopaedics Authors: Francyelle Borges Rosa de Moura, Bruno Antonio Ferreira, Elusca Helena Muniz, Allisson Benatti Justino, Ana Gabriela Silva, Rinara de Almeida Santos, Jos é Augusto Leôncio Gomide, Rosy Iara Maciel de Azambuja Ribeiro, Daniele Lisboa Ribeiro, Fernanda de Source Type: research
Antimicrobial activity of < em > Annona muricata < /em > leaf oleoresin
This study aimed to determine the antimicrobial activity and chemical composition of Annona muricata leaf oleoresin obtained by supercritical CO2 extraction. The oleoresin was obtained by supercritical CO2 extraction and the chemical identification by gas chromatography coupled to mass spectrometry. Antimicrobial activity was evaluated by broth microdilution method against 14 foodborne fungi and bacteria. The oleoresin major chemical class was phytosterols (22.7%) and the major compounds were γ-sitosterol (15.7%), α-tocopherol (13.7%), phytol (13.1%), and hexadecanoic acid (11.5%). Minimum inhibitory concentration agains...
Source: Natural Product Research - December 6, 2021 Category: Biochemistry Authors: Caroline Zanella Cagnini Ang élica Barbosa Dias Mariana Rodrigues Vilas Boas Fabiana Pacheco Reis Batista Maria Graciela Iecher Faria Jasmina Glamo člija Marina Sokovi ć Vele Te šević Ederlan de Souza Ferreira Nelson Barros Colauto Giani Andrea Linde Source Type: research
Antimicrobial activity of < em > Annona muricata < /em > leaf oleoresin
This study aimed to determine the antimicrobial activity and chemical composition of Annona muricata leaf oleoresin obtained by supercritical CO2 extraction. The oleoresin was obtained by supercritical CO2 extraction and the chemical identification by gas chromatography coupled to mass spectrometry. Antimicrobial activity was evaluated by broth microdilution method against 14 foodborne fungi and bacteria. The oleoresin major chemical class was phytosterols (22.7%) and the major compounds were γ-sitosterol (15.7%), α-tocopherol (13.7%), phytol (13.1%), and hexadecanoic acid (11.5%). Minimum inhibitory concentration agains...
Source: Natural Product Research - December 6, 2021 Category: Biochemistry Authors: Caroline Zanella Cagnini Ang élica Barbosa Dias Mariana Rodrigues Vilas Boas Fabiana Pacheco Reis Batista Maria Graciela Iecher Faria Jasmina Glamo člija Marina Sokovi ć Vele Te šević Ederlan de Souza Ferreira Nelson Barros Colauto Giani Andrea Linde Source Type: research
Knowledge, Attitudes and Practices on the Use of Botanical Medicines in a Rural Caribbean Territory
The worldwide use of medicinal plant products has been steadily increasing over the past few decades, whereas the traditional knowledge and practices of these botanical medicines appears to be diminishing. Considering the need to conserve and document these traditions, the objective of this study was to understand the knowledge, attitudes, and practices of people who are familiar with botanical medicines, as well as any factors that may influence the perceptions and behaviours associated with the use of medicinal plants. A previously validated survey instrument assessing knowledge, attitudes, and practices on the use medic...
Source: Frontiers in Pharmacology - October 27, 2021 Category: Drugs & Pharmacology Source Type: research
Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity
Biomed Pharmacother. 2021 Oct 6;144:112263. doi: 10.1016/j.biopha.2021.112263. Online ahead of print.ABSTRACTThe tropical plant Annona muricata has been widely used for traditional ethnobotanic and pharmacologic applications. Extracts from different parts of this plant have been shown to have a wide range of biological activities. In the present study, we carry out a metabolomic study of both aqueous and DMSO extracts from Annona muricata leaves that has allowed us to identify 33 bioactive compounds. Furthermore, we have shown that aqueous extracts are able to inhibit endothelial cell migration and both aqueous and DMSO ex...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 9, 2021 Category: Drugs & Pharmacology Authors: Casimiro C árdenas Jos é Antonio Torres-Vargas Abel C árdenas-Valdivia Nuria Jurado Ana R Quesada Melissa Garc ía-Caballero Beatriz Mart ínez-Poveda Miguel Ángel Medina Source Type: research
Non-targeted metabolomics characterization of Annona muricata leaf extracts with anti-angiogenic activity
Biomed Pharmacother. 2021 Oct 6;144:112263. doi: 10.1016/j.biopha.2021.112263. Online ahead of print.ABSTRACTThe tropical plant Annona muricata has been widely used for traditional ethnobotanic and pharmacologic applications. Extracts from different parts of this plant have been shown to have a wide range of biological activities. In the present study, we carry out a metabolomic study of both aqueous and DMSO extracts from Annona muricata leaves that has allowed us to identify 33 bioactive compounds. Furthermore, we have shown that aqueous extracts are able to inhibit endothelial cell migration and both aqueous and DMSO ex...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - October 9, 2021 Category: Drugs & Pharmacology Authors: Casimiro C árdenas Jos é Antonio Torres-Vargas Abel C árdenas-Valdivia Nuria Jurado Ana R Quesada Melissa Garc ía-Caballero Beatriz Mart ínez-Poveda Miguel Ángel Medina Source Type: research
