Immunosuppressive Effects of Annona muricata L. Leaf Extract on Cellular and Humoral Immune Responses in Male Wistar Rats
CONCLUSION: The strong inhibitory effects on the different parameters of humoral and cellular responses indicate that AMLE has potential to be an important source of effective immunosuppressive agents.PMID:36545731 | DOI:10.2174/1389201024666221221113020 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - December 22, 2022 Category: Biotechnology Authors: Siti Mariam Abdul Wahab Khairana Husain Ibrahim Jantan Laiba Arshad Md Areeful Haque Norsyahida Mohd Fauzi Mohd Azlan Nafiah Srijit Das Source Type: research

Immunosuppressive Effects of Annona muricata L. Leaf Extract on Cellular and Humoral Immune Responses in Male Wistar Rats
Curr Pharm Biotechnol. 2022 Dec 21. doi: 10.2174/1389201024666221221113020. Online ahead of print.NO ABSTRACTPMID:36545731 | DOI:10.2174/1389201024666221221113020 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - December 22, 2022 Category: Biotechnology Authors: Siti Mariam Abdul Wahab Khairana Husain Ibrahim Jantan Laiba Arshad Md Areeful Haque Norsyahida Mohd Fauzi Mohd Azlan Nafiah Srijit Das Source Type: research

Polysaccharides from < em > Annona  muricata < /em > leaves protect against cisplatin ‑induced cytotoxicity in macrophages by alleviating mitochondrial dysfunction
Mol Med Rep. 2023 Jan;27(1):16. doi: 10.3892/mmr.2022.12903. Epub 2022 Dec 1.ABSTRACTCisplatin is a prominent chemotherapeutic agent that can induce significant damage to normal cells. Therefore, it is important to develop agents that protect normal cells without influencing the chemotherapeutic effect of cisplatin. The present study was conducted to explore the protective effects of Annona muricata leaf polysaccharides (ALPS) against cisplatin‑induced toxicity in macrophages. Apoptosis was assessed in macrophages and lung cancer cells to investigate the cytoprotective effect of ALPS, their effect on the production of ci...
Source: Molecular Medicine - December 1, 2022 Category: Molecular Biology Authors: Jeong Moo Han Ha-Yeon Song Kwang-Il Kim Woo Yong Park Sang-Hyun Park Eui-Baek Byun Eui-Hong Byun Source Type: research

Polysaccharides from < em > Annona  muricata < /em > leaves protect against cisplatin ‑induced cytotoxicity in macrophages by alleviating mitochondrial dysfunction
Mol Med Rep. 2023 Jan;27(1):16. doi: 10.3892/mmr.2022.12903. Epub 2022 Dec 1.ABSTRACTCisplatin is a prominent chemotherapeutic agent that can induce significant damage to normal cells. Therefore, it is important to develop agents that protect normal cells without influencing the chemotherapeutic effect of cisplatin. The present study was conducted to explore the protective effects of Annona muricata leaf polysaccharides (ALPS) against cisplatin‑induced toxicity in macrophages. Apoptosis was assessed in macrophages and lung cancer cells to investigate the cytoprotective effect of ALPS, their effect on the production of ci...
Source: Molecular Medicine Reports - December 1, 2022 Category: Molecular Biology Authors: Jeong Moo Han Ha-Yeon Song Kwang-Il Kim Woo Yong Park Sang-Hyun Park Eui-Baek Byun Eui-Hong Byun Source Type: research

Effect of Annona muricata aqueous leaf extract on reactive oxygen and nitrogen species
CONCLUSIONS: The results themselves show that the effects of A. muricata leaf extract are mainly mediated by the activity against •OH, as well as the consequences of increased ONO2- formation.PMID:36196736 | DOI:10.26355/eurrev_202209_29748 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - October 5, 2022 Category: Drugs & Pharmacology Authors: M Vidov á Uğurbaş D Ogur čáková M Haus I Boro ňová L Čuchráč J Va šková Source Type: research

Effect of Annona muricata aqueous leaf extract on reactive oxygen and nitrogen species
CONCLUSIONS: The results themselves show that the effects of A. muricata leaf extract are mainly mediated by the activity against •OH, as well as the consequences of increased ONO2- formation.PMID:36196736 | DOI:10.26355/eurrev_202209_29748 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - October 5, 2022 Category: Drugs & Pharmacology Authors: M Vidov á Uğurbaş D Ogur čáková M Haus I Boro ňová L Čuchráč J Va šková Source Type: research

Effect of Annona muricata aqueous leaf extract on reactive oxygen and nitrogen species
CONCLUSIONS: The results themselves show that the effects of A. muricata leaf extract are mainly mediated by the activity against •OH, as well as the consequences of increased ONO2- formation.PMID:36196736 | DOI:10.26355/eurrev_202209_29748 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - October 5, 2022 Category: Drugs & Pharmacology Authors: M Vidov á Uğurbaş D Ogur čáková M Haus I Boro ňová L Čuchráč J Va šková Source Type: research

Effect of Annona muricata aqueous leaf extract on reactive oxygen and nitrogen species
CONCLUSIONS: The results themselves show that the effects of A. muricata leaf extract are mainly mediated by the activity against •OH, as well as the consequences of increased ONO2- formation.PMID:36196736 | DOI:10.26355/eurrev_202209_29748 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - October 5, 2022 Category: Drugs & Pharmacology Authors: M Vidov á Uğurbaş D Ogur čáková M Haus I Boro ňová L Čuchráč J Va šková Source Type: research