Potential of Indonesian Herbal as an Anti-Cancer Therapy: A Systemic Review of in vitro Studies
CONCLUSION: The most widely studied Indonesian herbal plant in vitro as an anti-cancer is Soursop, while the anti-cancer activity that is widely reported is by inhibiting cell proliferation through intrinsic pathways.PMID:37608914 | PMC:PMC10441583 | DOI:10.2147/CMAR.S414457 (Source: Cell Research)
Source: Cell Research - August 23, 2023 Category: Cytology Authors: Ayu Permatasanti Wahyu Hidayat Source Type: research
Investigations into Annona fruit consumption as a potential source of dietary higenamine intake in the context of sports drug testing
In this study, however, the MRL was not exceeded at any time point. Further, the major urinary excretion of higenamine in its sulfo-conjugated form was corroborated, its stability in urine was assessed, and in the absence of reference material, higenamine sulfo-conjugates were synthesized and comprehensively characterized, suggesting the predominant presence of higenamine 7-sulfate. In addition, the option to include complementary biomarkers of diet-related higenamine intake into routine doping controls was investigated. A characteristic urinary pattern attributed to isococlaurine, reticuline, and a yet not fully character...
Source: Drug Testing and Analysis - August 2, 2023 Category: Drugs & Pharmacology Authors: Ana Rubio,
Andreas Thomas,
Luisa Euler,
Hans Geyer,
Oliver Krug,
Gabriel Reis,
Monica Costa Padilha,
Henrique Marcelo Gualberto Pereira,
Renan Muniz ‐Santos,
Luiz Claudio Cameron,
Biljana Stojanovic,
Dirk Kuehne,
Andreas Lagojda,
Malcolm Do Tags: RESEARCH ARTICLE Source Type: research
Molecules, Vol. 28, Pages 5744: LCMS/MS Phytochemical Profiling, Molecular, Pathological, and Immune-Histochemical Studies on the Anticancer Properties of Annona muricata
ahnaa M. Atta
Annona muricate is a tropical plant that is well-known for its edible fruit of therapeutic interest. LCMS/MS analyses were applied to identify phytoconstituents of the ethanolic extract of the whole fruits and the aqueous extract of the edible fruit part, in addition to the investigation of their anticancer properties against Ehrlich ascites carcinoma (EAC) in male albino mice. LCMS/MS analyses resulted in the identification of 388 components, representing a wide array of classes of compounds, including acetogenins as the major constituents, alkaloids, flavonoids, and phenolics. Among them, four compounds...
Source: Molecules - July 29, 2023 Category: Chemistry Authors: Rehab H. Abdallah Muneera S. M. Al-Saleem Wael M. Abdel-Mageed Al-Sayed R. Al-Attar Youssef M. Shehata Doaa M. Abdel-Fattah Rahnaa M. Atta Tags: Article Source Type: research
Comparative anticancer effects of Annona muricata Linn (Annonaceae) leaves and fruits on DMBA-induced breast cancer in female rats
CONCLUSION: These results confirm the anti-breast cancer effect of A. muricata, however, the aqueous fruit extract was more potent than the ethanolic leaves extract.PMID:37454062 | PMC:PMC10349462 | DOI:10.1186/s12906-023-04073-x (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - July 15, 2023 Category: Information Technology Authors: Kevine Kamga Silihe William Defo Mbou Judith Christiane Ngo Pambe Larissa Vanelle Kenmogne Laure Fotso Maptouom Marius Tr ésor Kemegne Sipping St éphane Zingue Dieudonn é Njamen Source Type: research
Comparative anticancer effects of Annona muricata Linn (Annonaceae) leaves and fruits on DMBA-induced breast cancer in female rats
CONCLUSION: These results confirm the anti-breast cancer effect of A. muricata, however, the aqueous fruit extract was more potent than the ethanolic leaves extract.PMID:37454062 | DOI:10.1186/s12906-023-04073-x (Source: Cancer Control)
Source: Cancer Control - July 15, 2023 Category: Cancer & Oncology Authors: Kevine Kamga Silihe William Defo Mbou Judith Christiane Ngo Pambe Larissa Vanelle Kenmogne Laure Fotso Maptouom Marius Tr ésor Kemegne Sipping St éphane Zingue Dieudonn é Njamen Source Type: research
Comparative anticancer effects of Annona muricata Linn (Annonaceae) leaves and fruits on DMBA-induced breast cancer in female rats
CONCLUSION: These results confirm the anti-breast cancer effect of A. muricata, however, the aqueous fruit extract was more potent than the ethanolic leaves extract.PMID:37454062 | PMC:PMC10349462 | DOI:10.1186/s12906-023-04073-x (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - July 15, 2023 Category: Information Technology Authors: Kevine Kamga Silihe William Defo Mbou Judith Christiane Ngo Pambe Larissa Vanelle Kenmogne Laure Fotso Maptouom Marius Tr ésor Kemegne Sipping St éphane Zingue Dieudonn é Njamen Source Type: research
Comparative anticancer effects of Annona muricata Linn (Annonaceae) leaves and fruits on DMBA-induced breast cancer in female rats
CONCLUSION: These results confirm the anti-breast cancer effect of A. muricata, however, the aqueous fruit extract was more potent than the ethanolic leaves extract.PMID:37454062 | PMC:PMC10349462 | DOI:10.1186/s12906-023-04073-x (Source: Methods of Information in Medicine)
Source: Methods of Information in Medicine - July 15, 2023 Category: Information Technology Authors: Kevine Kamga Silihe William Defo Mbou Judith Christiane Ngo Pambe Larissa Vanelle Kenmogne Laure Fotso Maptouom Marius Tr ésor Kemegne Sipping St éphane Zingue Dieudonn é Njamen Source Type: research
Comparative anticancer effects of Annona muricata Linn (Annonaceae) leaves and fruits on DMBA-induced breast cancer in female rats
Numerous studies have reported the anti-cancer effects of different parts of Annona muricata Linn, however ; most of them focused on the in vitro evaluation of isolates. In vivo evidence on which part is best sui... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - July 15, 2023 Category: Complementary Medicine Authors: Kevine Kamga Silihe, William Defo Mbou, Judith Christiane Ngo Pambe, Larissa Vanelle Kenmogne, Laure Fotso Maptouom, Marius Tr ésor Kemegne Sipping, Stéphane Zingue and Dieudonné Njamen Tags: Research Source Type: research
An evaluation of the quality of Annona muricata leaf products
CONCLUSIONS: The variation in the indicators of quality and safety of commercially available A. muricata leaf products tested have implications for clinicians and people living with cancer who use these herbal products.PMID:37440207 | DOI:10.1093/jpp/rgad066 (Source: Cancer Control)
Source: Cancer Control - July 13, 2023 Category: Cancer & Oncology Authors: Wai-Jo Jocelin Chan Joanna E Harnett Alexandra Meroni Andrew J McLachlan Jane R Hanrahan Source Type: research
Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects
CONCLUSION: A simple and validated HPLC method was used to determine CBZ levels in rats' plasma. The plasma CBZ levels (Cmax) were significantly reduced in the presence of GFE, indicating the importance of drug-herb interactions. For in vitro studies, two human cancer cell lines, MCF-7 (breast cancer cells) and PC3 (prostate cancer cells), were used to screen the cytotoxicity activity of GFE, CBZ, and VPA. We observed an antagonism effect for GFE and CBZ combination in both cell lines with FIC values > 4. On the contrary, the combination of GFE and VPA showed an additive or indifferent effect.PMID:37378914 | DOI:10.3155...
Source: Asian Pacific Journal of Cancer Prevention - June 28, 2023 Category: Cancer & Oncology Authors: Asma Abdelqader Abu Soukhon Luay Abu-Qatouseh Kenza Mansoor Feras Darwish El-Hajji Mohammad Al-Najjar Shady Awwad Riad Awad Khaled W Omari Eyad Mallah Source Type: research
