Phenolic Compounds and Metals in Some Edible Annonaceae Fruits.
Abstract
The concentrations of 3,4-dihydroxybenzoic acid, caffeic acid, catechin, chlorogenic acid, epicatechin, gallic acid, p-coumaric acid, quercetin, rutin, ferulic acid, and the major metals in graviola (Annona muricata), atemoya (A. squamosa x A. cherimola), fruta do conde (A. squamosa), biribá (Rollinia mucosa), and the North American pawpaw (Asimina triloba) were determined by UPLC-ESI (-)-MS/MS. It enabled the identification and quantification of phenolic compounds. Catechin was only found in atemoya, at a concentration of 38.6 μg/g-dw. Only 3,4-dihydroxybenzoic acid was found in the fruit pulp...
Source: Biological Trace Element Research - January 6, 2020 Category: Biology Authors: de Moraes MR, Ryan SM, Godoy HT, Thomas AL, Maia JGS, Richards KM, Tran K, Smith RE Tags: Biol Trace Elem Res Source Type: research
Complementary and alternative medicine in cancer - A qualitative study on the Internet offer in Spanish-speaking South America.
CONCLUSIONS: There is an urgent need for quality-assured, easy-to-find sites with high quality for Spanish speaking persons in South America. Several of the methods have already spread to Europe as graviola or uncaria.
PMID: 31987227 [PubMed - in process] (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - December 31, 2019 Category: Complementary Medicine Authors: van de Loo RJE, Mechtenberg E, Huebner J, Keinki C Tags: Complement Ther Med Source Type: research
The safety and tolerability of Annona muricata leaf extract: a systematic review
ConclusionsThe overall outcome of the current review suggests thatA. muricata has a favourable safety and tolerability profile. Future studies investigating its use in people diagnosed with a range of cancers are warranted. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - December 9, 2019 Category: Drugs & Pharmacology Authors: Wai ‐Jo Jocelin Chan,
Andrew J. McLachlan,
Jane R. Hanrahan,
Joanna E. Harnett Tags: Review Source Type: research
Protective potentials of Annona muricata fruit pulp on etoposide-induced gastrointestinal toxicity in Wistar rats.
CONCLUSION: The results show that AM fruit pulp has the capacity to act as antimucositic agent and also reduced inflammation.
PMID: 31807120 [PubMed] (Source: Journal of Carcinogenesis)
Source: Journal of Carcinogenesis - December 7, 2019 Category: Cancer & Oncology Tags: J Carcinog Source Type: research
Molecules, Vol. 24, Pages 4419: Anti-Infective and Anti-Cancer Properties of the Annona Species: Their Ethnomedicinal Uses, Alkaloid Diversity, and Pharmacological Activities
Keller
Annona species have been a valuable source of anti-infective and anticancer agents. However, only limited evaluations of their alkaloids have been carried out. This review collates and evaluates the biological data from extracts and purified isolates for their anti-infective and anti-cancer activities. An isoquinoline backbone is a major structural alkaloid moiety of the Annona genus, and more than 83 alkaloids have been isolated from this genus alone. Crude extracts of Annona genus are reported with moderate activities against Plasmodium falciparum showing larvicidal activities. However, no pure compounds from...
Source: Molecules - December 2, 2019 Category: Chemistry Authors: Ari Satia Nugraha Yuvita Dian Damayanti Phurpa Wangchuk Paul A. Keller Tags: Review Source Type: research
Efficacy of a Peruvian Botanical Remedy (Sabell A4+) for Treating Liver Disease and Protecting Gastric Mucosal Integrity.
We report the efficacy of A4+ and its components using a variety of in vitro and in vivo disease models. The methods used included tests for antioxidant, anti-inflammatory, and antiviral activity as well as mouse models of liver disease, including Concanavalin A-induced immune-mediated hepatitis and a bile duct ligation model for evaluating sickness behaviour associated with liver disease. Rat models were used to evaluate the gastric mucosal protective property of A4+ following indomethacin challenge and to evaluate its anti-inflammatory action in an "air pouch" model. In all tests, A4+ proved to be more effective than pla...
Source: Evidence-based Complementary and Alternative Medicine - December 1, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Effect of vacuum-thermosonication on the inactivation of Escherichia coli, Staphylococcus aureus, polyphenol oxidase and the quality parameters of soursop puree
Publication date: Available online 18 November 2019Source: Innovative Food Science & Emerging TechnologiesAuthor(s): Oscar G. Martínez-Moreno, Luis M. Anaya-Esparza, Jorge A. Sánchez-Burgos, Libier Meza-Espinoza, Alejandro Pérez-Larios, J. Emanuel Bojorquez-Quintal, Efigenia Montalvo-GonzálezAbstractThe combined effect of vacuum, heat and ultrasound (vacuum-thermosonication, VTS) on soursop puree was investigated with regard to the viability of Escherichia coli and Staphylococcus aureus, inactivation of polyphenol oxidase and sensory quality. The VTS conditions were: vacuum (8.46, 11 and 16.93 kPa), heat (40, 45 and ...
Source: Innovative Food Science and Emerging Technologies - November 19, 2019 Category: Food Science Source Type: research
How does the degree of inulin polymerization affect the bioaccessibility of bioactive compounds from soursop whey beverage during in vitro gastrointestinal digestion?
Publication date: Available online 12 November 2019Source: Food HydrocolloidsAuthor(s): Jonas T. Guimarães, Eric Keven Silva, Henrique S. Arruda, Monica Q. Freitas, Glaucia M. Pastore, M. Angela A. Meireles, Adriano G. CruzAbstractThe inulin is known as a prebiotic carbohydrate with beneficial health properties in addition to its technological properties as a texture modifier and stabilizer of food products. Despite that, a little is known about the influence of the degree of inulin polymerization during gastrointestinal digestion. Then, the objective of this study was to evaluate if the degree of inulin polymerization in...
Source: Food Hydrocolloids - November 12, 2019 Category: Food Science Source Type: research
The safety and tolerability of Annona muricata leaf extract: a systematic review
ConclusionsThe overall outcome of the current review suggests thatA. muricata has a favourable safety and tolerability profile. Future studies investigating its use in people diagnosed with a range of cancers are warranted. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - October 27, 2019 Category: Drugs & Pharmacology Authors: Wai ‐Jo Jocelin Chan,
Andrew J. McLachlan,
Jane R. Hanrahan,
Joanna E. Harnett Tags: Review Source Type: research
Non-thermal processing of inulin-enriched soursop whey beverage using supercritical carbon dioxide technology
Publication date: Available online 21 September 2019Source: The Journal of Supercritical FluidsAuthor(s): Eric Keven Silva, Jonas T. Guimarães, Ana Letícia R. Costa, Adriano G. Cruz, M. Angela A. MeirelesAbstractThe effects of supercritical CO2 technology on the non-thermal processing of soursop (Annona muricata L.) whey beverage enriched with inulin, a prebiotic carbohydrate, were analyzed. The functional dairy beverage was processed employing different supercritical process conditions: 35 and 55 °C, 10 and 20 MPa, and a CO2 volume ratio of 20 and 50%. Physicochemical properties (pH, soluble solids, ζ-potential), ...
Source: The Journal of Supercritical Fluids - September 22, 2019 Category: Chemistry Source Type: research
Graviola Fruit Bar Added Acerola By-Product Extract Protects Against Inflammation and Nociception in Adult Zebrafish (Danio rerio)
Journal of Medicinal Food, Ahead of Print. (Source: Journal of Medicinal Food)
Source: Journal of Medicinal Food - September 8, 2019 Category: Nutrition Authors: Larissa Morais Ribeiro da Silva Jorgiane da Silva Severino Lima Franscisco Ernani Alves Magalh ães Adriana Rolim Campos Jos é Ismael Feitosa de Araújo Francisco Lucas Alves Batista Sandra Maria Barbosa de Ara újo Paulo Henrique Machado de Sousa Glaube Source Type: research
Modulation of cancer signalling pathway(s) in two -stage mouse skin tumorigenesis by annonacin
Annonacin, an annonaceous acetogenin isolated from Annona muricata has been reported to be strongly cytotoxic against various cell lines, in vitro. Nevertheless, its effect against in vivo tumor promoting activit... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - September 3, 2019 Category: Complementary Medicine Authors: Mohd Rohaizad Md Roduan, Roslida Abd Hamid and Norhafizah Mohtarrudin Tags: Research article Source Type: research
Practical Application of “About Herbs” Website: Herbs and Dietary Supplement Use in Oncology Settings
The Integrative Medicine Service at Memorial Sloan Kettering Cancer Center developed and maintains About Herbs (www.aboutherbs.com), which provides summaries of research data including purported uses, adverse effects, and herb-drug interactions for about 284 dietary supplements. Using Google Analytics, we found the website registered more than 26,317,000 hits since November 2002. The 10 most searched-for herbs/supplements of 2018 are chaga mushroom, turmeric, ashwagandha, reishi mushroom, graviola, Active Hexose-Correlated Compound, boswellia, dandelion, green tea, and Coriolus versicolor. Here we discuss their safety, her...
Source: The Cancer Journal - September 1, 2019 Category: Cancer & Oncology Tags: Review Articles Source Type: research
Practical Application of "About Herbs" Website: Herbs and Dietary Supplement Use in Oncology Settings.
Abstract
The Integrative Medicine Service at Memorial Sloan Kettering Cancer Center developed and maintains About Herbs (www.aboutherbs.com), which provides summaries of research data including purported uses, adverse effects, and herb-drug interactions for about 284 dietary supplements. Using Google Analytics, we found the website registered more than 26,317,000 hits since November 2002. The 10 most searched-for herbs/supplements of 2018 are chaga mushroom, turmeric, ashwagandha, reishi mushroom, graviola, Active Hexose-Correlated Compound, boswellia, dandelion, green tea, and Coriolus versicolor. Here we...
Source: Cancer Journal - August 31, 2019 Category: Cancer & Oncology Authors: Hou YN, Deng G, Mao JJ Tags: Cancer J Source Type: research
The effects of soursop supplementation on blood pressure, serum uric acid, and kidney function in a prehypertensive population in accordance with the 2017 ACC/AHA guideline
Journal of Human Hypertension, Published online: 28 August 2019; doi:10.1038/s41371-019-0235-6The effects of soursop supplementation on blood pressure, serum uric acid, and kidney function in a prehypertensive population in accordance with the 2017 ACC/AHA guideline (Source: Journal of Human Hypertension)
Source: Journal of Human Hypertension - August 27, 2019 Category: Cardiology Authors: Haidar Alatas Mochammad Sja ’bani Mustofa Mustofa Ali Ghufron Mukti Lucky A. Bawazier Fredie Irijanto Zulaela Zulaela Yasuhiko Tomino Source Type: research
