Extending neutron autoradiography technique for boron concentration measurements in hard tissues.
Abstract
The neutron autoradiography technique using polycarbonate nuclear track detectors (NTD) has been extended to quantify the boron concentration in hard tissues, an application of special interest in Boron Neutron Capture Therapy (BNCT). Chemical and mechanical processing methods to prepare thin tissue sections as required by this technique have been explored. Four different decalcification methods governed by slow and fast kinetics were tested in boron-loaded bones. Due to the significant loss of the boron content, this technique was discarded. On the contrary, mechanical manipulation to obtain bone...
Source: Applied Radiation and Isotopes - March 14, 2018 Category: Radiology Authors: Provenzano L, Olivera MS, Saint Martin G, Rodríguez LM, Fregenal D, Thorp SI, Pozzi ECC, Curotto P, Postuma I, Altieri S, González SJ, Bortolussi S, Portu A Tags: Appl Radiat Isot Source Type: research
Acute Hemorrhagic Encephalitis Responding to Combined Decompressive Craniectomy, Intravenous Immunoglobulin, and Corticosteroid Therapies: Association with Novel RANBP2 Variant
Abdulla Alawadhi, Christine Saint-Martin, Farhan Bhanji, Myriam Srour, Jeffrey Atkinson, Guillaume S ébire (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - March 12, 2018 Category: Neurology Source Type: research
Intrathyroidal thymic tissue in children: Avoiding unnecessary surgery
Intrathyroidal thymic tissue may be misinterpreted as a thyroid lesion in children, leading to invasive tests or resection. We sought to describe the characteristic imaging features of these lesions and to evaluate the safety of non-operative management. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - March 6, 2018 Category: Surgery Authors: Emily Kay-Rivest, Marco A. Mascarella, Pramod Puligandla, Sherif Emil, Christine Saint-Martin, Lily H.P. Nguyen, Sam J. Daniel, Robert Baird Source Type: research
Evaporation process in histological tissue sections for neutron autoradiography.
Abstract
The analysis of the distribution and density of nuclear tracks forming an autoradiography in a nuclear track detector (NTD) allows the determination of 10B atoms concentration and location in tissue samples from Boron Neutron Capture Therapy (BNCT) protocols. This knowledge is of great importance for BNCT dosimetry and treatment planning. Tissue sections studied with this technique are obtained by cryosectioning frozen tissue specimens. After the slicing procedure, the tissue section is put on the NTD and the sample starts drying. The thickness varies from its original value allowing more particle...
Source: Radiation and Environmental Biophysics - February 23, 2018 Category: Physics Authors: Espector NM, Portu A, Santa Cruz GA, Saint Martin G Tags: Radiat Environ Biophys Source Type: research
Leptospira seroprevalence in animals in the Caribbean region: a systematic review.
Abstract
This systematic review summarises the data published on the Leptospira seroprevalence, serovar diversity and distribution among animal species in the Caribbean region. Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, and checklist, relevant articles were identified and data were extracted and recorded. The review provided Leptospira seroprevalence data from 16 Caribbean islands (Barbados, Trinidad, Grenada, Puerto Rico, Saint Croix, St. Kitts and Nevis, Jamaica, Antigua, Carriacou, Dominica, Guadalupe, Martinique, Monserrat, St. Lucia, St. Maarten, ...
Source: Acta Tropica - February 16, 2018 Category: Infectious Diseases Authors: Pratt N, Rajeev S Tags: Acta Trop Source Type: research
Illness Severity Predicts Death and Brain Injury in Asphyxiated Newborns Treated with Hypothermia
Conclusion In asphyxiated newborns treated with hypothermia, not only the initial asphyxial event but also the illness severity during the first days of life was a significant predictor of death or brain injury. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - February 16, 2018 Category: Perinatology & Neonatology Authors: Wang, Hui Beltempo, Marc Rampakakis, Emmanouil Sanon, Priscille-Nice Barbosa Vargas, Stephanie Maluorni, Julie Saint-Martin, Christine Wintermark, Pia Tags: Original Article Source Type: research
Letter to the Editor regarding Hackl et al: “Rare implant-specific complications of the MoPyC radial head prosthesis”
It was with great interest that we read the article “Rare implant-specific complications of the MoPyC radial head prosthesis” by Hackl et al.6 The MoPyC implant (Tornier [Bioprofile], Montbonnot-Saint-Martin, France) is a monopolar, press-fit radial head prosthesis that obtains fixation via auto-expansion of its stem; this implant design is not c urrently available for use in the United States. Although functional outcomes are promising, the description and analysis of the complications of MoPyC implants in the literature are scarce. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - February 10, 2018 Category: Orthopaedics Authors: Pierre Laumonerie, Stephanie Declaux, Nicolas Reina, Nicolas Bonnevialle, Pierre Mansat, Meagan E. Tibbo Tags: Letter to the Editor Source Type: research
[Retinal venous malformation].
Authors: de Saint-Martin G, Bresson T, Trélohan A
PMID: 29290460 [PubMed - as supplied by publisher] (Source: Journal Francais d Ophtalmologie)
Source: Journal Francais d Ophtalmologie - January 3, 2018 Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
Using "isotopic spike" from tropical storm to understand water exchange on large scale: case study of Hurricane Rafael in the Lesser Antilles archipelago, October 2012.
CONCLUSIONS: The "isotopic spikes" generated by tropical storms, are generally used to track back past storm events, as recorded in trees and stalagmites. Here, the propagation of isotopic spike is followed to improve the understanding of the freshwater circulation and the water dynamic within coastal ecosystems influenced by seawater.
PMID: 29314392 [PubMed - as supplied by publisher] (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - January 3, 2018 Category: Chemistry Authors: Lambs L, Bompy F, Dulormne M Tags: Rapid Commun Mass Spectrom Source Type: research
Tracking the career development of scientists in low- and middle-income countries trained through TDR ’s research capacity strengthening programmes: Learning from monitoring and impact evaluation
by B éatrice Halpaap, Mahnaz Vahedi, Edith Certain, Tini Alvarado, Caroline Saint Martin, Corinne Merle, Michael Mihut, Pascal Launois
The Special Programme for Research and Training in Tropical Diseases (TDR) co-sponsored by UNICEF, UNDP, World Bank and WHO has been supporting research capacity strengthening in low- and middle-income countries for over 40 years. In order to assess and continuously optimize its capacity strengthe ning approaches, an evaluation of the influence of TDR training grants on research career development was undertaken. The assessment was part of a larger evaluation conducted by the European Sci...
Source: PLoS Neglected Tropical Diseases - December 7, 2017 Category: Tropical Medicine Authors: B éatrice Halpaap Source Type: research
Defining the phenotypic spectrum of SLC6A1 mutations
We describe 7 truncating and 18 missense variants, including 4 recurrent variants (Gly232Val, Ala288Val, Val342Met, and Gly362Arg).
SignificanceMost patients carrying pathogenic SLC6A1 variants have an MAE phenotype with language delay and mild/moderate ID before epilepsy onset. However, ID alone or associated with focal epilepsy can also be observed. (Source: Epilepsia)
Source: Epilepsia - December 1, 2017 Category: Neurology Authors: Katrine M. Johannesen, Elena Gardella, Tarja Linnankivi, Carolina Courage, Anne Saint Martin, Anna ‐Elina Lehesjoki, Cyril Mignot, Alexandra Afenjar, Gaetan Lesca, Marie‐Thérèse Abi‐Warde, Jamel Chelly, Amélie Piton, J. Lawrence Merritt, Lance H. Tags: FULL ‐LENGTH ORIGINAL RESEARCH Source Type: research
Brain Temperature Is Increased During the First Days of Life in Asphyxiated Newborns: Developing Brain Injury Despite Hypothermia Treatment [PEDIATRICS]
CONCLUSIONS:
Therapeutic hypothermia using current guidelines decreased the brain temperature of neonates with hypoxic-ischemic encephalopathy during the first days of life but did not prevent an early increase of brain temperature in neonates with hypoxic-ischemic encephalopathy who developed brain injury despite this treatment. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - November 15, 2017 Category: Radiology Authors: Owji, Z. P., Gilbert, G., Saint-Martin, C., Wintermark, P. Tags: PEDIATRICS Source Type: research
Long-lasting active lifestyle and successful cognitive aging in a healthy elderly population: The PROOF cohort.
CONCLUSION: In the healthy elderly, high cognitive ability predicts both cognitive ability and social involvement in later life. Cognitive decline by only one level may also extend the time to reach impairment, underlining the importance of the so-called cognitive reserve.
PMID: 29100612 [PubMed - as supplied by publisher] (Source: Revue Neurologique)
Source: Revue Neurologique - November 5, 2017 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
Diabetes, Associated Clinical Spectrum, Long-term Prognosis, and Genotype/Phenotype Correlations in 201 Adult Patients With Hepatocyte Nuclear Factor 1B (HNF1B) Molecular Defects
CONCLUSIONS
In patients with HNF1B syndrome, diabetes complications, cardiovascular risk factors, CKD3–4, and ESRD are highly prevalent. At diabetes diagnosis, the presence of morphological and/or functional kidney disease may help etiological diagnosis. Genotype/phenotype correlations may have implications for the care and the prognosis of these patients. (Source: Diabetes Care)
Source: Diabetes Care - October 23, 2017 Category: Endocrinology Authors: Dubois-Laforgue, D.; Cornu, E.; Saint-Martin, C.; Coste, J.; Bellanne-Chantelot, C.; Timsit, J.; for the Monogenic Diabetes Study Group of the Societe Francophone du Diabete Tags: Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research
