Cerebral white matter abnormalities associated with chromosome 18q duplication
Chromosome 18q duplications are associated with a range of phenotypes often similar to complete trisomy 18, variably including poor growth, feeding difficulties, congenital malformations and dysmorphic facial features. Although 18q duplication patients may have seizures and developmental impairment, brain MRI typically shows only variable degrees of cerebral atrophy. (Source: Brain and Development)
Source: Brain and Development - April 22, 2022 Category: Neurology Authors: Jiayin Huang, Christine Saint-Martin, Guergana Tchakarska, Jos ée Lavoie, Kenneth A. Myers Tags: Case Report Source Type: research

Structure and enzymatic degradation of the polysaccharide secreted by Nostoc commune
Carbohydr Res. 2022 Mar 28;515:108544. doi: 10.1016/j.carres.2022.108544. Online ahead of print.ABSTRACTNoctoc commune is a cyanobacterium living in various and extreme environments. Its ability to survive in desert, on ice or high altitude is explained by its exceptional metabolism and its capacity to resist to desiccation. N. commune cells are embedded in a gelatinous matrix made of polysaccharides which fixes water and participates in maintaining the cells in hydrated conditions. The structure of the polysaccharide of N. commune harvested in Saint Martin d'Uriage (France) and the oligosaccharides obtained after its enzy...
Source: Carbohydrate Research - April 3, 2022 Category: Genetics & Stem Cells Authors: Sophie Drouillard Laurent Poulet Eric Marechal Alberto Amato Laurine Buon M élanie Loiodice William Helbert Source Type: research

Structure and enzymatic degradation of the polysaccharide secreted by Nostoc commune
Carbohydr Res. 2022 Mar 28;515:108544. doi: 10.1016/j.carres.2022.108544. Online ahead of print.ABSTRACTNoctoc commune is a cyanobacterium living in various and extreme environments. Its ability to survive in desert, on ice or high altitude is explained by its exceptional metabolism and its capacity to resist to desiccation. N. commune cells are embedded in a gelatinous matrix made of polysaccharides which fixes water and participates in maintaining the cells in hydrated conditions. The structure of the polysaccharide of N. commune harvested in Saint Martin d'Uriage (France) and the oligosaccharides obtained after its enzy...
Source: Carbohydrate Research - April 3, 2022 Category: Genetics & Stem Cells Authors: Sophie Drouillard Laurent Poulet Eric Marechal Alberto Amato Laurine Buon M élanie Loiodice William Helbert Source Type: research

Structure and enzymatic degradation of the polysaccharide secreted by Nostoc commune
Carbohydr Res. 2022 Mar 28;515:108544. doi: 10.1016/j.carres.2022.108544. Online ahead of print.ABSTRACTNoctoc commune is a cyanobacterium living in various and extreme environments. Its ability to survive in desert, on ice or high altitude is explained by its exceptional metabolism and its capacity to resist to desiccation. N. commune cells are embedded in a gelatinous matrix made of polysaccharides which fixes water and participates in maintaining the cells in hydrated conditions. The structure of the polysaccharide of N. commune harvested in Saint Martin d'Uriage (France) and the oligosaccharides obtained after its enzy...
Source: Carbohydrate Research - April 3, 2022 Category: Genetics & Stem Cells Authors: Sophie Drouillard Laurent Poulet Eric Marechal Alberto Amato Laurine Buon M élanie Loiodice William Helbert Source Type: research

Structure and enzymatic degradation of the polysaccharide secreted by Nostoc commune
Carbohydr Res. 2022 Mar 28;515:108544. doi: 10.1016/j.carres.2022.108544. Online ahead of print.ABSTRACTNoctoc commune is a cyanobacterium living in various and extreme environments. Its ability to survive in desert, on ice or high altitude is explained by its exceptional metabolism and its capacity to resist to desiccation. N. commune cells are embedded in a gelatinous matrix made of polysaccharides which fixes water and participates in maintaining the cells in hydrated conditions. The structure of the polysaccharide of N. commune harvested in Saint Martin d'Uriage (France) and the oligosaccharides obtained after its enzy...
Source: Carbohydrate Research - April 3, 2022 Category: Genetics & Stem Cells Authors: Sophie Drouillard Laurent Poulet Eric Marechal Alberto Amato Laurine Buon M élanie Loiodice William Helbert Source Type: research

Structure and enzymatic degradation of the polysaccharide secreted by Nostoc commune
Carbohydr Res. 2022 Mar 28;515:108544. doi: 10.1016/j.carres.2022.108544. Online ahead of print.ABSTRACTNoctoc commune is a cyanobacterium living in various and extreme environments. Its ability to survive in desert, on ice or high altitude is explained by its exceptional metabolism and its capacity to resist to desiccation. N. commune cells are embedded in a gelatinous matrix made of polysaccharides which fixes water and participates in maintaining the cells in hydrated conditions. The structure of the polysaccharide of N. commune harvested in Saint Martin d'Uriage (France) and the oligosaccharides obtained after its enzy...
Source: Carbohydrate Research - April 3, 2022 Category: Genetics & Stem Cells Authors: Sophie Drouillard Laurent Poulet Eric Marechal Alberto Amato Laurine Buon M élanie Loiodice William Helbert Source Type: research

Structure and enzymatic degradation of the polysaccharide secreted by Nostoc commune
Carbohydr Res. 2022 Mar 28;515:108544. doi: 10.1016/j.carres.2022.108544. Online ahead of print.ABSTRACTNoctoc commune is a cyanobacterium living in various and extreme environments. Its ability to survive in desert, on ice or high altitude is explained by its exceptional metabolism and its capacity to resist to desiccation. N. commune cells are embedded in a gelatinous matrix made of polysaccharides which fixes water and participates in maintaining the cells in hydrated conditions. The structure of the polysaccharide of N. commune harvested in Saint Martin d'Uriage (France) and the oligosaccharides obtained after its enzy...
Source: Carbohydrate Research - April 3, 2022 Category: Genetics & Stem Cells Authors: Sophie Drouillard Laurent Poulet Eric Marechal Alberto Amato Laurine Buon M élanie Loiodice William Helbert Source Type: research

Structure and enzymatic degradation of the polysaccharide secreted by Nostoc commune
Carbohydr Res. 2022 Mar 28;515:108544. doi: 10.1016/j.carres.2022.108544. Online ahead of print.ABSTRACTNoctoc commune is a cyanobacterium living in various and extreme environments. Its ability to survive in desert, on ice or high altitude is explained by its exceptional metabolism and its capacity to resist to desiccation. N. commune cells are embedded in a gelatinous matrix made of polysaccharides which fixes water and participates in maintaining the cells in hydrated conditions. The structure of the polysaccharide of N. commune harvested in Saint Martin d'Uriage (France) and the oligosaccharides obtained after its enzy...
Source: Carbohydrate Research - April 3, 2022 Category: Genetics & Stem Cells Authors: Sophie Drouillard Laurent Poulet Eric Marechal Alberto Amato Laurine Buon M élanie Loiodice William Helbert Source Type: research

Larrea divaricata: anti-inflammatory and antioxidant effects of on macrophages and low density lipoproteins
CONCLUSIONS: These results suggest a potential usefulness of AE as an adjuvant phytotherapy in patients with diabetes mellitus and atherosclerosis.PMID:35321702 | DOI:10.1186/s12906-022-03547-8 (Source: Atherosclerosis)
Source: Atherosclerosis - March 24, 2022 Category: Cardiology Authors: Ignacio Peralta Carla Marrassini Malen Saint Martin Laura Cogoi Mar ía Rosario Alonso Alejandro Gugliucci Claudia Anesini Source Type: research

Larrea divaricata: anti-inflammatory and antioxidant effects of on macrophages and low density lipoproteins
The oxidized low density lipoprotein (ox-LDL) contributes to inflammation and oxidative stress through the activation of macrophages under hyperglycemia contributing to the development of diabetes mellitus and... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - March 23, 2022 Category: Complementary Medicine Authors: Ignacio Peralta, Carla Marrassini, Malen Saint Martin, Laura Cogoi, Mar ía Rosario Alonso, Alejandro Gugliucci and Claudia Anesini Tags: Research Source Type: research

Efficacy of trastuzumab emtansine (T-DM1) and lapatinib after dual HER2 inhibition with trastuzumab and pertuzumab in patient with metastatic breast cancer: Retrospective data from a French multicenter real-life cohort
CONCLUSION: First-line trastuzumab plus pertuzumab do not markedly diminish T-DM1's efficacy in second-line. Similarly, sequential treatment with trastuzumab plus pertuzumab then T-DM1 does not noticeably modify the efficacy of lapatinib plus capecitabine.PMID:35299035 | DOI:10.1016/j.breast.2022.03.004 (Source: Breast)
Source: Breast - March 17, 2022 Category: Cancer & Oncology Authors: Fabien Moinard-Butot Caroline Saint-Martin Carole Pflumio Matthieu Carton William Jacot Paul-Henri Cottu V éronique Diéras Florence Dalenc Anthony Goncalves Marc Debled Anne Patsouris Marie-Ange Mouret-Reynier Laurence Vanlemmens Marianne Leheurteur Geo Source Type: research

Efficacy of trastuzumab emtansine (T-DM1) and lapatinib after dual HER2 inhibition with trastuzumab and pertuzumab in patient with metastatic breast cancer: Retrospective data from a French multicenter real-life cohort
CONCLUSION: First-line trastuzumab plus pertuzumab do not markedly diminish T-DM1's efficacy in second-line. Similarly, sequential treatment with trastuzumab plus pertuzumab then T-DM1 does not noticeably modify the efficacy of lapatinib plus capecitabine.PMID:35299035 | PMC:PMC8927850 | DOI:10.1016/j.breast.2022.03.004 (Source: Breast)
Source: Breast - March 17, 2022 Category: Cancer & Oncology Authors: Fabien Moinard-Butot Caroline Saint-Martin Carole Pflumio Matthieu Carton William Jacot Paul-Henri Cottu V éronique Diéras Florence Dalenc Anthony Goncalves Marc Debled Anne Patsouris Marie-Ange Mouret-Reynier Laurence Vanlemmens Marianne Leheurteur Geo Source Type: research

Efficacy of trastuzumab emtansine (T-DM1) and lapatinib after dual HER2 inhibition with trastuzumab and pertuzumab in patient with metastatic breast cancer: Retrospective data from a French multicenter real-life cohort
CONCLUSION: First-line trastuzumab plus pertuzumab do not markedly diminish T-DM1's efficacy in second-line. Similarly, sequential treatment with trastuzumab plus pertuzumab then T-DM1 does not noticeably modify the efficacy of lapatinib plus capecitabine.PMID:35299035 | PMC:PMC8927850 | DOI:10.1016/j.breast.2022.03.004 (Source: Breast)
Source: Breast - March 17, 2022 Category: Cancer & Oncology Authors: Fabien Moinard-Butot Caroline Saint-Martin Carole Pflumio Matthieu Carton William Jacot Paul-Henri Cottu V éronique Diéras Florence Dalenc Anthony Goncalves Marc Debled Anne Patsouris Marie-Ange Mouret-Reynier Laurence Vanlemmens Marianne Leheurteur Geo Source Type: research

Efficacy of trastuzumab emtansine (T-DM1) and lapatinib after dual HER2 inhibition with trastuzumab and pertuzumab in patient with metastatic breast cancer: Retrospective data from a French multicenter real-life cohort
CONCLUSION: First-line trastuzumab plus pertuzumab do not markedly diminish T-DM1's efficacy in second-line. Similarly, sequential treatment with trastuzumab plus pertuzumab then T-DM1 does not noticeably modify the efficacy of lapatinib plus capecitabine.PMID:35299035 | PMC:PMC8927850 | DOI:10.1016/j.breast.2022.03.004 (Source: Breast)
Source: Breast - March 17, 2022 Category: Cancer & Oncology Authors: Fabien Moinard-Butot Caroline Saint-Martin Carole Pflumio Matthieu Carton William Jacot Paul-Henri Cottu V éronique Diéras Florence Dalenc Anthony Goncalves Marc Debled Anne Patsouris Marie-Ange Mouret-Reynier Laurence Vanlemmens Marianne Leheurteur Geo Source Type: research

Efficacy of trastuzumab emtansine (T-DM1) and lapatinib after dual HER2 inhibition with trastuzumab and pertuzumab in patient with metastatic breast cancer: Retrospective data from a French multicenter real-life cohort
CONCLUSION: First-line trastuzumab plus pertuzumab do not markedly diminish T-DM1's efficacy in second-line. Similarly, sequential treatment with trastuzumab plus pertuzumab then T-DM1 does not noticeably modify the efficacy of lapatinib plus capecitabine.PMID:35299035 | PMC:PMC8927850 | DOI:10.1016/j.breast.2022.03.004 (Source: Breast)
Source: Breast - March 17, 2022 Category: Cancer & Oncology Authors: Fabien Moinard-Butot Caroline Saint-Martin Carole Pflumio Matthieu Carton William Jacot Paul-Henri Cottu V éronique Diéras Florence Dalenc Anthony Goncalves Marc Debled Anne Patsouris Marie-Ange Mouret-Reynier Laurence Vanlemmens Marianne Leheurteur Geo Source Type: research