Unusual severe radiation-induced toxicity in a patient with discoid lupus erythematosus: A case report and critical review of the literature
Cancer Radiother. 2021 Oct 30:S1278-3218(21)00265-1. doi: 10.1016/j.canrad.2021.07.039. Online ahead of print.ABSTRACTData on the incidence and severity of radiation-induced toxicity in patients with systemic and/or cutaneous lupus erythematosus (SLE/CLE) are very limited. After reporting the case of a patient who experienced major toxicity and CLE flare in the irradiated area following breast irradiation, we conducted a comprehensive literature review of available data in this setting. The few retrospectives studies which have evaluated both the risk of toxicity in SLE/CLE patients and/or the potential induction or reacti...
Source: Cancer Radiotherapie - November 3, 2021 Category: Cancer & Oncology Authors: S Allali F Chasset Y Kirova C Saint-Martin P Moguelet A Fourquet A Beddok Source Type: research

Unusual severe radiation-induced toxicity in a patient with discoid lupus erythematosus: A case report and critical review of the literature
Cancer Radiother. 2021 Oct 30:S1278-3218(21)00265-1. doi: 10.1016/j.canrad.2021.07.039. Online ahead of print.ABSTRACTData on the incidence and severity of radiation-induced toxicity in patients with systemic and/or cutaneous lupus erythematosus (SLE/CLE) are very limited. After reporting the case of a patient who experienced major toxicity and CLE flare in the irradiated area following breast irradiation, we conducted a comprehensive literature review of available data in this setting. The few retrospectives studies which have evaluated both the risk of toxicity in SLE/CLE patients and/or the potential induction or reacti...
Source: Cancer Radiotherapie - November 3, 2021 Category: Cancer & Oncology Authors: S Allali F Chasset Y Kirova C Saint-Martin P Moguelet A Fourquet A Beddok Source Type: research

Unusual severe radiation-induced toxicity in a patient with discoid lupus erythematosus: A case report and critical review of the literature
Cancer Radiother. 2021 Oct 30:S1278-3218(21)00265-1. doi: 10.1016/j.canrad.2021.07.039. Online ahead of print.ABSTRACTData on the incidence and severity of radiation-induced toxicity in patients with systemic and/or cutaneous lupus erythematosus (SLE/CLE) are very limited. After reporting the case of a patient who experienced major toxicity and CLE flare in the irradiated area following breast irradiation, we conducted a comprehensive literature review of available data in this setting. The few retrospectives studies which have evaluated both the risk of toxicity in SLE/CLE patients and/or the potential induction or reacti...
Source: Cancer Radiotherapie - November 3, 2021 Category: Cancer & Oncology Authors: S Allali F Chasset Y Kirova C Saint-Martin P Moguelet A Fourquet A Beddok Source Type: research

Unusual severe radiation-induced toxicity in a patient with discoid lupus erythematosus: A case report and critical review of the literature
Cancer Radiother. 2021 Oct 30:S1278-3218(21)00265-1. doi: 10.1016/j.canrad.2021.07.039. Online ahead of print.ABSTRACTData on the incidence and severity of radiation-induced toxicity in patients with systemic and/or cutaneous lupus erythematosus (SLE/CLE) are very limited. After reporting the case of a patient who experienced major toxicity and CLE flare in the irradiated area following breast irradiation, we conducted a comprehensive literature review of available data in this setting. The few retrospectives studies which have evaluated both the risk of toxicity in SLE/CLE patients and/or the potential induction or reacti...
Source: Cancer Radiotherapie - November 3, 2021 Category: Cancer & Oncology Authors: S Allali F Chasset Y Kirova C Saint-Martin P Moguelet A Fourquet A Beddok Source Type: research

Distinctive neuroimaging pattern in term newborns with neonatal placental encephalopathy: A Case Series
Identifying antepartum versus intrapartum timing and the cause of neonatal encephalopathy (NE) often remains elusive due to our limited understanding of the underlying pathophysiological processes and lack of appropriate biomarkers. (Source: Pediatric Neurology)
Source: Pediatric Neurology - October 4, 2021 Category: Neurology Authors: Fatema Al Amrani, Guillaume S ébire, Moy Fong Chen, Pia Wintermark, Christine Saint-Martin Tags: Research Paper Source Type: research

Prevalence of precancerous cervical lesions and high-risk human papillomavirus types in Yaounde, Cameroon
Conclusions: Our results suggest that HPV 16 and 18 are predominant in Yaounde, and are associated with more severe precancerous lesions. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - September 29, 2021 Category: Infectious Diseases Source Type: research

Antiproliferative activity of aqueous and polyphenol-rich extracts of < em > Larrea divaricata < /em > Cav. on a melanoma cell line
The objective of this work was to evaluate the activity of the aqueous extract of Larrea divaricata (Aq), a fraction rich in polyphenols (EA),and the isolated compound quercetin-3-methyl ether (Q3ME) on B16F10 melanoma cells. The effects of Aq, EA and Q3ME were assessed on B16F10 cells by determining the proliferation, viability, apoptosis induction and the expression and phosphorylation of STAT3. The phytochemical composition of the extracts was determined by High Performance Liquid Chromatography. Aq, EA and Q3ME presented antiproliferative activity on B6F10 cells through p-STAT3 inhibition and early and late apoptosis i...
Source: Biomed Res - September 27, 2021 Category: Research Authors: Renzo Martino Mar ía Laura Barreiro Arcos Ignacio Peralta Carla Marrassini Elina Mal én Saint Martin Laura Cogoi Graciela Cremaschi Mar ía Rosario Alonso Claudia Anesini Source Type: research

Antiproliferative activity of aqueous and polyphenol-rich extracts of < em > Larrea divaricata < /em > Cav. on a melanoma cell line
The objective of this work was to evaluate the activity of the aqueous extract of Larrea divaricata (Aq), a fraction rich in polyphenols (EA),and the isolated compound quercetin-3-methyl ether (Q3ME) on B16F10 melanoma cells. The effects of Aq, EA and Q3ME were assessed on B16F10 cells by determining the proliferation, viability, apoptosis induction and the expression and phosphorylation of STAT3. The phytochemical composition of the extracts was determined by High Performance Liquid Chromatography. Aq, EA and Q3ME presented antiproliferative activity on B6F10 cells through p-STAT3 inhibition and early and late apoptosis i...
Source: Natural Product Research - September 27, 2021 Category: Biochemistry Authors: Renzo Martino Mar ía Laura Barreiro Arcos Ignacio Peralta Carla Marrassini Elina Mal én Saint Martin Laura Cogoi Graciela Cremaschi Mar ía Rosario Alonso Claudia Anesini Source Type: research

Antiproliferative activity of aqueous and polyphenol-rich extracts of < em > Larrea divaricata < /em > Cav. on a melanoma cell line
The objective of this work was to evaluate the activity of the aqueous extract of Larrea divaricata (Aq), a fraction rich in polyphenols (EA),and the isolated compound quercetin-3-methyl ether (Q3ME) on B16F10 melanoma cells. The effects of Aq, EA and Q3ME were assessed on B16F10 cells by determining the proliferation, viability, apoptosis induction and the expression and phosphorylation of STAT3. The phytochemical composition of the extracts was determined by High Performance Liquid Chromatography. Aq, EA and Q3ME presented antiproliferative activity on B6F10 cells through p-STAT3 inhibition and early and late apoptosis i...
Source: Biomed Res - September 27, 2021 Category: Research Authors: Renzo Martino Mar ía Laura Barreiro Arcos Ignacio Peralta Carla Marrassini Elina Mal én Saint Martin Laura Cogoi Graciela Cremaschi Mar ía Rosario Alonso Claudia Anesini Source Type: research

Antiproliferative activity of aqueous and polyphenol-rich extracts of < em > Larrea divaricata < /em > Cav. on a melanoma cell line
The objective of this work was to evaluate the activity of the aqueous extract of Larrea divaricata (Aq), a fraction rich in polyphenols (EA),and the isolated compound quercetin-3-methyl ether (Q3ME) on B16F10 melanoma cells. The effects of Aq, EA and Q3ME were assessed on B16F10 cells by determining the proliferation, viability, apoptosis induction and the expression and phosphorylation of STAT3. The phytochemical composition of the extracts was determined by High Performance Liquid Chromatography. Aq, EA and Q3ME presented antiproliferative activity on B6F10 cells through p-STAT3 inhibition and early and late apoptosis i...
Source: Natural Product Research - September 27, 2021 Category: Biochemistry Authors: Renzo Martino Mar ía Laura Barreiro Arcos Ignacio Peralta Carla Marrassini Elina Mal én Saint Martin Laura Cogoi Graciela Cremaschi Mar ía Rosario Alonso Claudia Anesini Source Type: research

PO-0992 Outcomes and toxicities of curative reirradiation for head and neck carcinomas
(Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - August 1, 2021 Category: Radiology Authors: A. Beddok, C. Saint-Martin, C. Ala Eddine, L. Champion, S. Krhili, A. Chilles, L. Catteau, F. Goudjil, S. Sefkili, M. Amessis, D. Peurien, O. Choussy, C. Le Tourneau, R. Dendale, I. Buvat, G. Cr éhange, V. Calugaru Tags: Digital Poster: Head and neck Source Type: research

OC-0628 Regional Control after Stereotactic Radiation therapy and Immunotherapy for NSCLC Brain Metastases
(Source: Radiotherapy and Oncology)
Source: Radiotherapy and Oncology - August 1, 2021 Category: Radiology Authors: J. Porte, C. Saint-Martin, T. Frederic-Moreau, M. Massiani, E. Jadaud, J. Otz, P. Verrelle, N. Girard, G. Cr éhange, A. Beddok Tags: Proffered papers: Proffered papers 37: Immuno and targeted agents Source Type: research

Interdisciplinary community-based participatory health research across the industrial region of the Étang de Berre : The EPSEAL Fos Crau study
CONCLUSION: We encourage future researchers to do in-depth, community-based research to comprehensively describe the health of residents in other heavily polluted zones, product local knowledge and to help identify policy solutions, engender trust among the local people, and identify opportunities for intervention.PMID:34256985 | DOI:10.1016/j.respe.2021.04.141 (Source: Revue d Epidemiologie et de Sante Publique)
Source: Revue d Epidemiologie et de Sante Publique - July 14, 2021 Category: Epidemiology Authors: Maxime Jeanjean Johanna Lees Barbara L Allen Alison K Cohen Source Type: research