Dose optimization in 3D pulsed dose rate brachytherapy for patients with locally advanced cervical cancer: A French multicenter phase II trial
CONCLUSION: HR CTV dose was below the target (85Gy) due to low use of parametrial interstitial needles, as the centers did not always have an adequate applicator, or were at the time at the beginning of their learning curve. The 5-year LC rate was improved compared to that of the comparable STIC PDR group (78%) but lower than the retroEMBRACE cohort of GEC ESTRO (89%). The complication rate was higher than in the comparable group of STIC PDR but close to that of retroEMBRACE. Training brachytherapy teams in interstitial implantation or referring patients to referral centers should help improve the therapeutic index of cerv...
Source: Cancer Radiotherapie - July 24, 2021 Category: Cancer & Oncology Authors: C Charra-Brunaud J Salleron I Menoux K Peignaux A Ducassou A Petit P Pommier I Barillot A A Serre L Thomas M Delannes D Thibouw D Antoni S Renard D Peiffert Source Type: research

Does every woman require a post-lumpectomy mammogram and ultrasound before radiotherapy when negative margins?
CONCLUSION: PLI detected residual local cancer in 1.0% of the patients. PLI plays an important role in the evaluation of patients undergoing breast-conserving therapy with negative margins. The major question that remains is whether it changes survival outcomes.PMID:34284966 | DOI:10.1016/j.canrad.2021.06.020 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: A Pires J Rodrigues H G Pereira Source Type: research

Cooperation protocol and advanced practice, an evolutionary perspective for the French radiation therapist
This article aims to reflect the evolution's perspectives in the career of an RTT and on the valorisation of this profession in the current context.PMID:34284967 | DOI:10.1016/j.canrad.2021.06.022 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: P Le Tallec S Corbin S Ahado S Boisbouvier Source Type: research

Evaluation of quality of life: Clinical relevance for patient
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00128-1. doi: 10.1016/j.canrad.2021.06.029. Online ahead of print.ABSTRACTThe quality of life of patients and its evaluation remains one of the primordial objectives in oncology. Different methods and tools of evaluation of quality of life have been developed with the objective of having a global evaluation, throughout different aspects, be it physical, emotional, psychological or social. The quality of life questionnaires improve and simplify the reevaluation and follow-up of patients during clinical trials. Patient reported outcome measures (PROMs) are an evaluation of the qual...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: C Dossun B V Popescu D Antoni Source Type: research

Role of proton therapy in reirradiation and in the treatment of sarcomas
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00123-2. doi: 10.1016/j.canrad.2021.06.024. Online ahead of print.ABSTRACTReirradiation and irradiation of sarcoma is often difficult due to the frequent need for a high dose of radiation in order to increase tumor control. This can result in a greater risk of toxicity which can be mitigated with the use of proton therapy. The present review aims to summarize the role of proton therapy in these 2 clinical contexts.PMID:34284969 | DOI:10.1016/j.canrad.2021.06.024 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: J Doyen D Aloi A Groulier M Vidal P Lesueur V Calugaru P Y Bondiau Source Type: research

Artificial intelligence, radiomics and pathomics to predict response and survival of patients treated with radiations
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00126-8. doi: 10.1016/j.canrad.2021.06.027. Online ahead of print.ABSTRACTArtificial intelligence approaches in medicine are more and more used and are extremely promising due to the growing number of data produced and the variety of data they allow to exploit. Thus, the computational analysis of medical images in particular, radiological (radiomics), or anatomopathological (pathomics), has shown many very interesting results for the prediction of the prognosis and the response of cancer patients. Radiotherapy is a discipline that particularly benefits from these new approaches b...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: R Sun M Lerousseau T Henry A Carr é A Leroy T Estienne S Niyoteka S Bockel A Rouyar É Alvarez Andres N Benzazon E Battistella M Classe C Robert J Y Scoazec É Deutsch Source Type: research

Extreme hypofractionated radiation therapy for pancreatic cancer
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00151-7. doi: 10.1016/j.canrad.2021.06.031. Online ahead of print.ABSTRACTPancreatic cancer has poor prognosis and a continuously growing incidence. By 2030, it should become the second cause of death by cancer worldwide and in France. The only curative treatment is surgery that is achievable in only 20% of patients at the time of initial diagnosis, with a high rate of incomplete resection. Neoadjuvant treatments using chemotherapy with or without radiotherapy are more often admitted to play an important role by selecting non-progressing cases who will benefit from surgery, by in...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: M Rouffiac S Ghirardi C Chevalier I Bessi ères K Peignaux-Casasnovas G Truc G Cr éhange Source Type: research

Does every woman require a post-lumpectomy mammogram and ultrasound before radiotherapy when negative margins?
CONCLUSION: PLI detected residual local cancer in 1.0% of the patients. PLI plays an important role in the evaluation of patients undergoing breast-conserving therapy with negative margins. The major question that remains is whether it changes survival outcomes.PMID:34284966 | DOI:10.1016/j.canrad.2021.06.020 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: A Pires J Rodrigues H G Pereira Source Type: research

Cooperation protocol and advanced practice, an evolutionary perspective for the French radiation therapist
This article aims to reflect the evolution's perspectives in the career of an RTT and on the valorisation of this profession in the current context.PMID:34284967 | DOI:10.1016/j.canrad.2021.06.022 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: P Le Tallec S Corbin S Ahado S Boisbouvier Source Type: research

Evaluation of quality of life: Clinical relevance for patient
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00128-1. doi: 10.1016/j.canrad.2021.06.029. Online ahead of print.ABSTRACTThe quality of life of patients and its evaluation remains one of the primordial objectives in oncology. Different methods and tools of evaluation of quality of life have been developed with the objective of having a global evaluation, throughout different aspects, be it physical, emotional, psychological or social. The quality of life questionnaires improve and simplify the reevaluation and follow-up of patients during clinical trials. Patient reported outcome measures (PROMs) are an evaluation of the qual...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: C Dossun B V Popescu D Antoni Source Type: research

Role of proton therapy in reirradiation and in the treatment of sarcomas
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00123-2. doi: 10.1016/j.canrad.2021.06.024. Online ahead of print.ABSTRACTReirradiation and irradiation of sarcoma is often difficult due to the frequent need for a high dose of radiation in order to increase tumor control. This can result in a greater risk of toxicity which can be mitigated with the use of proton therapy. The present review aims to summarize the role of proton therapy in these 2 clinical contexts.PMID:34284969 | DOI:10.1016/j.canrad.2021.06.024 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: J Doyen D Aloi A Groulier M Vidal P Lesueur V Calugaru P Y Bondiau Source Type: research

Artificial intelligence, radiomics and pathomics to predict response and survival of patients treated with radiations
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00126-8. doi: 10.1016/j.canrad.2021.06.027. Online ahead of print.ABSTRACTArtificial intelligence approaches in medicine are more and more used and are extremely promising due to the growing number of data produced and the variety of data they allow to exploit. Thus, the computational analysis of medical images in particular, radiological (radiomics), or anatomopathological (pathomics), has shown many very interesting results for the prediction of the prognosis and the response of cancer patients. Radiotherapy is a discipline that particularly benefits from these new approaches b...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: R Sun M Lerousseau T Henry A Carr é A Leroy T Estienne S Niyoteka S Bockel A Rouyar É Alvarez Andres N Benzazon E Battistella M Classe C Robert J Y Scoazec É Deutsch Source Type: research

Extreme hypofractionated radiation therapy for pancreatic cancer
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00151-7. doi: 10.1016/j.canrad.2021.06.031. Online ahead of print.ABSTRACTPancreatic cancer has poor prognosis and a continuously growing incidence. By 2030, it should become the second cause of death by cancer worldwide and in France. The only curative treatment is surgery that is achievable in only 20% of patients at the time of initial diagnosis, with a high rate of incomplete resection. Neoadjuvant treatments using chemotherapy with or without radiotherapy are more often admitted to play an important role by selecting non-progressing cases who will benefit from surgery, by in...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: M Rouffiac S Ghirardi C Chevalier I Bessi ères K Peignaux-Casasnovas G Truc G Cr éhange Source Type: research

Does every woman require a post-lumpectomy mammogram and ultrasound before radiotherapy when negative margins?
CONCLUSION: PLI detected residual local cancer in 1.0% of the patients. PLI plays an important role in the evaluation of patients undergoing breast-conserving therapy with negative margins. The major question that remains is whether it changes survival outcomes.PMID:34284966 | DOI:10.1016/j.canrad.2021.06.020 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: A Pires J Rodrigues H G Pereira Source Type: research

Cooperation protocol and advanced practice, an evolutionary perspective for the French radiation therapist
This article aims to reflect the evolution's perspectives in the career of an RTT and on the valorisation of this profession in the current context.PMID:34284967 | DOI:10.1016/j.canrad.2021.06.022 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: P Le Tallec S Corbin S Ahado S Boisbouvier Source Type: research

Evaluation of quality of life: Clinical relevance for patient
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00128-1. doi: 10.1016/j.canrad.2021.06.029. Online ahead of print.ABSTRACTThe quality of life of patients and its evaluation remains one of the primordial objectives in oncology. Different methods and tools of evaluation of quality of life have been developed with the objective of having a global evaluation, throughout different aspects, be it physical, emotional, psychological or social. The quality of life questionnaires improve and simplify the reevaluation and follow-up of patients during clinical trials. Patient reported outcome measures (PROMs) are an evaluation of the qual...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: C Dossun B V Popescu D Antoni Source Type: research

Role of proton therapy in reirradiation and in the treatment of sarcomas
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00123-2. doi: 10.1016/j.canrad.2021.06.024. Online ahead of print.ABSTRACTReirradiation and irradiation of sarcoma is often difficult due to the frequent need for a high dose of radiation in order to increase tumor control. This can result in a greater risk of toxicity which can be mitigated with the use of proton therapy. The present review aims to summarize the role of proton therapy in these 2 clinical contexts.PMID:34284969 | DOI:10.1016/j.canrad.2021.06.024 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: J Doyen D Aloi A Groulier M Vidal P Lesueur V Calugaru P Y Bondiau Source Type: research

Artificial intelligence, radiomics and pathomics to predict response and survival of patients treated with radiations
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00126-8. doi: 10.1016/j.canrad.2021.06.027. Online ahead of print.ABSTRACTArtificial intelligence approaches in medicine are more and more used and are extremely promising due to the growing number of data produced and the variety of data they allow to exploit. Thus, the computational analysis of medical images in particular, radiological (radiomics), or anatomopathological (pathomics), has shown many very interesting results for the prediction of the prognosis and the response of cancer patients. Radiotherapy is a discipline that particularly benefits from these new approaches b...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: R Sun M Lerousseau T Henry A Carr é A Leroy T Estienne S Niyoteka S Bockel A Rouyar É Alvarez Andres N Benzazon E Battistella M Classe C Robert J Y Scoazec É Deutsch Source Type: research

Extreme hypofractionated radiation therapy for pancreatic cancer
Cancer Radiother. 2021 Jul 17:S1278-3218(21)00151-7. doi: 10.1016/j.canrad.2021.06.031. Online ahead of print.ABSTRACTPancreatic cancer has poor prognosis and a continuously growing incidence. By 2030, it should become the second cause of death by cancer worldwide and in France. The only curative treatment is surgery that is achievable in only 20% of patients at the time of initial diagnosis, with a high rate of incomplete resection. Neoadjuvant treatments using chemotherapy with or without radiotherapy are more often admitted to play an important role by selecting non-progressing cases who will benefit from surgery, by in...
Source: Cancer Radiotherapie - July 21, 2021 Category: Cancer & Oncology Authors: M Rouffiac S Ghirardi C Chevalier I Bessi ères K Peignaux-Casasnovas G Truc G Cr éhange Source Type: research

Clinical and technical considerations for mediastinal Hodgkin lymphoma protontherapy based on a single-center early experience
CONCLUSION: Despite notable dosimetric superiority over photon radiotherapy and excellent clinical tolerance, lack of availability of protontherapy facilities limit implementation of mediastinal Hodgkin lymphoma protontherapy. Additionally, strict selection criteria must be defined.PMID:34275748 | DOI:10.1016/j.canrad.2021.06.016 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 19, 2021 Category: Cancer & Oncology Authors: P Loap F Goudjil R Dendale Y Kirova Source Type: research

Clinical and technical considerations for mediastinal Hodgkin lymphoma protontherapy based on a single-center early experience
CONCLUSION: Despite notable dosimetric superiority over photon radiotherapy and excellent clinical tolerance, lack of availability of protontherapy facilities limit implementation of mediastinal Hodgkin lymphoma protontherapy. Additionally, strict selection criteria must be defined.PMID:34275748 | DOI:10.1016/j.canrad.2021.06.016 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 19, 2021 Category: Cancer & Oncology Authors: P Loap F Goudjil R Dendale Y Kirova Source Type: research

Clinical and technical considerations for mediastinal Hodgkin lymphoma protontherapy based on a single-center early experience
CONCLUSION: Despite notable dosimetric superiority over photon radiotherapy and excellent clinical tolerance, lack of availability of protontherapy facilities limit implementation of mediastinal Hodgkin lymphoma protontherapy. Additionally, strict selection criteria must be defined.PMID:34275748 | DOI:10.1016/j.canrad.2021.06.016 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 19, 2021 Category: Cancer & Oncology Authors: P Loap F Goudjil R Dendale Y Kirova Source Type: research

Ultra-hypofractionated radiotherapy for the treatment of localized prostate cancer: Results, limits and prospects
Cancer Radiother. 2021 Jul 14:S1278-3218(21)00127-X. doi: 10.1016/j.canrad.2021.06.028. Online ahead of print.ABSTRACTStill an emerging approach a few years ago, stereotactic body radiation therapy (SBRT) has ranked as a valid option for the treatment of localized prostate cancer. Inherent properties of prostatic adenocarcinoma (low α/β) make it the perfect candidate. We propose a critical review of the literature trying to put results into perspective to identify their strengths, limits and axes of development. Technically sophisticated, the stereotactic irradiation of the prostate is well tolerated. Despite th...
Source: Cancer Radiotherapie - July 18, 2021 Category: Cancer & Oncology Authors: P Graff G Crehange Source Type: research

Under-recognized toxicities of cranial irradiation
This article proposes to develop these toxicities, without being exhaustive, to allow a better apprehension of cranial irradiation in current context.PMID:34274224 | DOI:10.1016/j.canrad.2021.06.019 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 18, 2021 Category: Cancer & Oncology Authors: M Le Guyader D Antoni Source Type: research

Is cancer a prognostic factor for severe COVID-19, especially for breast cancer patients?
Cancer Radiother. 2021 Jul 1:S1278-3218(21)00114-1. doi: 10.1016/j.canrad.2021.06.015. Online ahead of print.ABSTRACTThe coronavirus disease 2019 (COVID-19) pandemic has caused a global upheaval in our health care system. Our hospital facilities have been subjected to a major influx of patients and the prevention of cross-contamination has been a key issue in the spread of the virus. New recommendations for good hygiene practice and new recommendations for disease management have emerged to limit the spread of the virus and reorganize the provision of care in key services. Many studies have attempted to identify factors th...
Source: Cancer Radiotherapie - July 18, 2021 Category: Cancer & Oncology Authors: S Allali A Beddok Y Kirova Source Type: research

State of art of photobiomodulation in the management of radiotherapy adverse events: Indications and level of evidence
CONCLUSION: The published data suggest that PBM may be considered as a full-fledged supportive care for patients treated with radiotherapy, or at least in the setting of a therapeutic clinical trial. However, until strong evidence has been published on its long-term safety, the use of PBM should be considered with caution, specifically when applied near areas with proven or potential tumors. The patient should be informed of the theoretical benefits and risks of PBM in order to obtain his informed consent before treatment.PMID:34272181 | DOI:10.1016/j.canrad.2021.06.025 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 17, 2021 Category: Cancer & Oncology Authors: G Klausner R J Bensadoun A Champion D Benzaquen C H Canova A Claren V Mancuso J Suhl R Balard I Troussier Source Type: research

Future technological developments in proton therapy  - A predicted technological breakthrough
This article presents an overview of on-going technical developments and innovations that we felt were most important today, as well as those that have the potential to significantly shape the future of proton therapy. Indeed, efforts have been done continuously to improve the efficiency of a PT system, in terms of cost, technology and delivery technics, and a number of different developments pursued in the accelerator field will first be presented. Significant developments are also underway in terms of transport and spatial resolution achievable with pencil beam scanning, or conformation of the dose to the target: we will...
Source: Cancer Radiotherapie - July 17, 2021 Category: Cancer & Oncology Authors: M Vidal C Moignier A Patriarca M Sotiropoulos T Schneider L De Marzi Source Type: research

Head and neck proton therapy in France: A missed opportunity or a challenge in front of us?
Cancer Radiother. 2021 Jul 13:S1278-3218(21)00117-7. doi: 10.1016/j.canrad.2021.06.018. Online ahead of print.ABSTRACTFollowing major advances of the best of photon-techniques such as intensity-modulated radiotherapy (IMRT), stereotactic body radiotherapy (SBRT) and, to arrive soon, magnetic resonance (MR)-linac radiotherapy, there are still substantial opportunities in the treatment of head and neck cancers to further reduce the toxicity burden. Proton therapy represents another attractive option in this high-quality and highly competitive precision radiotherapy landscape. Proton therapy holds promises to reduce toxicitie...
Source: Cancer Radiotherapie - July 17, 2021 Category: Cancer & Oncology Authors: J Thariat V Calugaru D Aloi P Maingon V Gr égoire Source Type: research

Bone metastasis: Efficacy and technical modalities of classical radiotherapy
Cancer Radiother. 2021 Jul 12:S1278-3218(21)00120-7. doi: 10.1016/j.canrad.2021.06.021. Online ahead of print.ABSTRACTConventional radiotherapy is a pivotal treatment in the management of bone metastasis. It is indicated primarily for palliative, analgesic, or decompressive purposes and in the prevention of severe bone events such as fractures and spinal cord compressions. It should be performed as early as possible from the onset of symptoms or within 14days following a surgical procedure of decompression or bone stabilization. Except in some cases, a pattern of 8Gy single dose is currently recommended, possibly renewable...
Source: Cancer Radiotherapie - July 16, 2021 Category: Cancer & Oncology Authors: E Rapeaud C Meynard F Lecante C Durdux Source Type: research

Rectal cancer: Towards personalized medicine
Cancer Radiother. 2021 Jul 12:S1278-3218(21)00125-6. doi: 10.1016/j.canrad.2021.06.026. Online ahead of print.ABSTRACTThe standard of care for patients with locally advanced rectal cancer has recently changed and is now based on the concept of total neoadjuvant therapy with the association of radiotherapy and systemic chemotherapy before radical surgery. The addition of noeadjuvant systemic chemotherapy before or after radiotherapy during preoperative course significantly decreased the risk of distant metastases and prolonged disease-free survival after surgery. The risk of recurrence varies among patients and the standard...
Source: Cancer Radiotherapie - July 16, 2021 Category: Cancer & Oncology Authors: V Vendrely S Benoist Source Type: research

Bone metastasis: Efficacy and technical modalities of classical radiotherapy
Cancer Radiother. 2021 Jul 12:S1278-3218(21)00120-7. doi: 10.1016/j.canrad.2021.06.021. Online ahead of print.ABSTRACTConventional radiotherapy is a pivotal treatment in the management of bone metastasis. It is indicated primarily for palliative, analgesic, or decompressive purposes and in the prevention of severe bone events such as fractures and spinal cord compressions. It should be performed as early as possible from the onset of symptoms or within 14days following a surgical procedure of decompression or bone stabilization. Except in some cases, a pattern of 8Gy single dose is currently recommended, possibly renewable...
Source: Cancer Radiotherapie - July 16, 2021 Category: Cancer & Oncology Authors: E Rapeaud C Meynard F Lecante C Durdux Source Type: research

Rectal cancer: Towards personalized medicine
Cancer Radiother. 2021 Jul 12:S1278-3218(21)00125-6. doi: 10.1016/j.canrad.2021.06.026. Online ahead of print.ABSTRACTThe standard of care for patients with locally advanced rectal cancer has recently changed and is now based on the concept of total neoadjuvant therapy with the association of radiotherapy and systemic chemotherapy before radical surgery. The addition of noeadjuvant systemic chemotherapy before or after radiotherapy during preoperative course significantly decreased the risk of distant metastases and prolonged disease-free survival after surgery. The risk of recurrence varies among patients and the standard...
Source: Cancer Radiotherapie - July 16, 2021 Category: Cancer & Oncology Authors: V Vendrely S Benoist Source Type: research

Efficacy and tolerance of salvage curative radiotherapy for patients with cervical relapse of differentiated thyroid carcinoma
CONCLUSION: Salvage cervical radiation therapy was associated with a locoregional control of 66.7% at 2years with a reasonable toxicity rate. Carboplatin association with radiation therapy did not improve locoregional control nor overall survival in comparison with radiotherapy alone.PMID:34253422 | DOI:10.1016/j.canrad.2021.06.013 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 13, 2021 Category: Cancer & Oncology Authors: P Giraud E Blais A Jouinot J Wasserman F M énégaux L Leenhardt P Maingon J-M Simon Source Type: research

Efficacy and tolerance of salvage curative radiotherapy for patients with cervical relapse of differentiated thyroid carcinoma
CONCLUSION: Salvage cervical radiation therapy was associated with a locoregional control of 66.7% at 2years with a reasonable toxicity rate. Carboplatin association with radiation therapy did not improve locoregional control nor overall survival in comparison with radiotherapy alone.PMID:34253422 | DOI:10.1016/j.canrad.2021.06.013 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 13, 2021 Category: Cancer & Oncology Authors: P Giraud E Blais A Jouinot J Wasserman F M énégaux L Leenhardt P Maingon J-M Simon Source Type: research

Efficacy and tolerance of salvage curative radiotherapy for patients with cervical relapse of differentiated thyroid carcinoma
CONCLUSION: Salvage cervical radiation therapy was associated with a locoregional control of 66.7% at 2years with a reasonable toxicity rate. Carboplatin association with radiation therapy did not improve locoregional control nor overall survival in comparison with radiotherapy alone.PMID:34253422 | DOI:10.1016/j.canrad.2021.06.013 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 13, 2021 Category: Cancer & Oncology Authors: P Giraud E Blais A Jouinot J Wasserman F M énégaux L Leenhardt P Maingon J-M Simon Source Type: research

Application of a new methodology of a priori risk analysis in a radiotherapy department
Cancer Radiother. 2021 Jul 1:S1278-3218(21)00105-0. doi: 10.1016/j.canrad.2021.06.007. Online ahead of print.ABSTRACTSince 2017, IRSN has been developing a new proactive risk analysis method. The Work Complexity Sharing and Exploration Spaces (EPECT in French) were tested for the first time in 2020 in the radiotherapy department of the Gustave Roussy Institute. The EPECT method makes it possible to anchor the analysis of risks incurred by patients in daily work situations and to involve the top management. The time required to involve the teams is comparable to or even less than that required for a conventional risk analys...
Source: Cancer Radiotherapie - July 5, 2021 Category: Cancer & Oncology Authors: S Thellier G Brusadin S Corbin E Deutsch Source Type: research

Application of a new methodology of a priori risk analysis in a radiotherapy department
Cancer Radiother. 2021 Jul 1:S1278-3218(21)00105-0. doi: 10.1016/j.canrad.2021.06.007. Online ahead of print.ABSTRACTSince 2017, IRSN has been developing a new proactive risk analysis method. The Work Complexity Sharing and Exploration Spaces (EPECT in French) were tested for the first time in 2020 in the radiotherapy department of the Gustave Roussy Institute. The EPECT method makes it possible to anchor the analysis of risks incurred by patients in daily work situations and to involve the top management. The time required to involve the teams is comparable to or even less than that required for a conventional risk analys...
Source: Cancer Radiotherapie - July 5, 2021 Category: Cancer & Oncology Authors: S Thellier G Brusadin S Corbin E Deutsch Source Type: research

Application of a new methodology of a priori risk analysis in a radiotherapy department
Cancer Radiother. 2021 Jul 1:S1278-3218(21)00105-0. doi: 10.1016/j.canrad.2021.06.007. Online ahead of print.ABSTRACTSince 2017, IRSN has been developing a new proactive risk analysis method. The Work Complexity Sharing and Exploration Spaces (EPECT in French) were tested for the first time in 2020 in the radiotherapy department of the Gustave Roussy Institute. The EPECT method makes it possible to anchor the analysis of risks incurred by patients in daily work situations and to involve the top management. The time required to involve the teams is comparable to or even less than that required for a conventional risk analys...
Source: Cancer Radiotherapie - July 5, 2021 Category: Cancer & Oncology Authors: S Thellier G Brusadin S Corbin E Deutsch Source Type: research

Application of a new methodology of a priori risk analysis in a radiotherapy department
Cancer Radiother. 2021 Jul 1:S1278-3218(21)00105-0. doi: 10.1016/j.canrad.2021.06.007. Online ahead of print.ABSTRACTSince 2017, IRSN has been developing a new proactive risk analysis method. The Work Complexity Sharing and Exploration Spaces (EPECT in French) were tested for the first time in 2020 in the radiotherapy department of the Gustave Roussy Institute. The EPECT method makes it possible to anchor the analysis of risks incurred by patients in daily work situations and to involve the top management. The time required to involve the teams is comparable to or even less than that required for a conventional risk analys...
Source: Cancer Radiotherapie - July 5, 2021 Category: Cancer & Oncology Authors: S Thellier G Brusadin S Corbin E Deutsch Source Type: research

Application of a new methodology of a priori risk analysis in a radiotherapy department
Cancer Radiother. 2021 Jul 1:S1278-3218(21)00105-0. doi: 10.1016/j.canrad.2021.06.007. Online ahead of print.ABSTRACTSince 2017, IRSN has been developing a new proactive risk analysis method. The Work Complexity Sharing and Exploration Spaces (EPECT in French) were tested for the first time in 2020 in the radiotherapy department of the Gustave Roussy Institute. The EPECT method makes it possible to anchor the analysis of risks incurred by patients in daily work situations and to involve the top management. The time required to involve the teams is comparable to or even less than that required for a conventional risk analys...
Source: Cancer Radiotherapie - July 5, 2021 Category: Cancer & Oncology Authors: S Thellier G Brusadin S Corbin E Deutsch Source Type: research

Application of a new methodology of a priori risk analysis in a radiotherapy department
Cancer Radiother. 2021 Jul 1:S1278-3218(21)00105-0. doi: 10.1016/j.canrad.2021.06.007. Online ahead of print.ABSTRACTSince 2017, IRSN has been developing a new proactive risk analysis method. The Work Complexity Sharing and Exploration Spaces (EPECT in French) were tested for the first time in 2020 in the radiotherapy department of the Gustave Roussy Institute. The EPECT method makes it possible to anchor the analysis of risks incurred by patients in daily work situations and to involve the top management. The time required to involve the teams is comparable to or even less than that required for a conventional risk analys...
Source: Cancer Radiotherapie - July 5, 2021 Category: Cancer & Oncology Authors: S Thellier G Brusadin S Corbin E Deutsch Source Type: research

R ôle of radiotherapy for sarcomas
Cancer Radiother. 2021 Jun 29:S1278-3218(21)00106-2. doi: 10.1016/j.canrad.2021.06.008. Online ahead of print.ABSTRACTThe quality of the initial management of sarcomas is fundamental because it conditions the patient's quality of life and his overall survival. Radiotherapy should be discussed in a multidisciplinary consultation meeting within the framework of the Netsarc+network. The place of radiotherapy in patients with soft tissue or bone sarcoma depends on the histology and tumour location, knowing that it is most often associated with surgery which remains the main treatment. It is part of the standard treatment for g...
Source: Cancer Radiotherapie - July 3, 2021 Category: Cancer & Oncology Authors: A Ducassou C Llacer P Sargos L Moureau-Zabotto M-P Sunyach J Thariat C Le P échoux Source Type: research

Implementation of the dematerialization of the patient file in the context of COVID in the ONCORAD radiotherapy units: Transition to "paperless"
Cancer Radiother. 2021 Jun 29:S1278-3218(21)00102-5. doi: 10.1016/j.canrad.2021.06.005. Online ahead of print.ABSTRACTPaper patient file sharing has clearly been identified as a risk behavior for the COVID-19 virus transmission in radiotherapy units. In order to overcome this, the ONCORAD radiotherapy units worked on total dematerialization of the paper patient file, within 3 weeks. The methodology is based on a quality approch. This work has led to a convincing improvement in the management of risks a priori and a smoother patient care workflow.PMID:34215522 | PMC:PMC8239946 | DOI:10.1016/j.canrad.2021.06.005 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 3, 2021 Category: Cancer & Oncology Authors: C Boutry A Sors K Meynard M D Zarate M S Couderc M V Delmas P Dudouet Source Type: research

R ôle of radiotherapy for sarcomas
Cancer Radiother. 2021 Jun 29:S1278-3218(21)00106-2. doi: 10.1016/j.canrad.2021.06.008. Online ahead of print.ABSTRACTThe quality of the initial management of sarcomas is fundamental because it conditions the patient's quality of life and his overall survival. Radiotherapy should be discussed in a multidisciplinary consultation meeting within the framework of the Netsarc+network. The place of radiotherapy in patients with soft tissue or bone sarcoma depends on the histology and tumour location, knowing that it is most often associated with surgery which remains the main treatment. It is part of the standard treatment for g...
Source: Cancer Radiotherapie - July 3, 2021 Category: Cancer & Oncology Authors: A Ducassou C Llacer P Sargos L Moureau-Zabotto M-P Sunyach J Thariat C Le P échoux Source Type: research

Implementation of the dematerialization of the patient file in the context of COVID in the ONCORAD radiotherapy units: Transition to "paperless"
Cancer Radiother. 2021 Jun 29:S1278-3218(21)00102-5. doi: 10.1016/j.canrad.2021.06.005. Online ahead of print.ABSTRACTPaper patient file sharing has clearly been identified as a risk behavior for the COVID-19 virus transmission in radiotherapy units. In order to overcome this, the ONCORAD radiotherapy units worked on total dematerialization of the paper patient file, within 3 weeks. The methodology is based on a quality approch. This work has led to a convincing improvement in the management of risks a priori and a smoother patient care workflow.PMID:34215522 | DOI:10.1016/j.canrad.2021.06.005 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 3, 2021 Category: Cancer & Oncology Authors: C Boutry A Sors K Meynard M D Zarate M S Couderc M V Delmas P Dudouet Source Type: research

R ôle of radiotherapy for sarcomas
Cancer Radiother. 2021 Jun 29:S1278-3218(21)00106-2. doi: 10.1016/j.canrad.2021.06.008. Online ahead of print.ABSTRACTThe quality of the initial management of sarcomas is fundamental because it conditions the patient's quality of life and his overall survival. Radiotherapy should be discussed in a multidisciplinary consultation meeting within the framework of the Netsarc+network. The place of radiotherapy in patients with soft tissue or bone sarcoma depends on the histology and tumour location, knowing that it is most often associated with surgery which remains the main treatment. It is part of the standard treatment for g...
Source: Cancer Radiotherapie - July 3, 2021 Category: Cancer & Oncology Authors: A Ducassou C Llacer P Sargos L Moureau-Zabotto M-P Sunyach J Thariat C Le P échoux Source Type: research

Implementation of the dematerialization of the patient file in the context of COVID in the ONCORAD radiotherapy units: Transition to "paperless"
Cancer Radiother. 2021 Jun 29:S1278-3218(21)00102-5. doi: 10.1016/j.canrad.2021.06.005. Online ahead of print.ABSTRACTPaper patient file sharing has clearly been identified as a risk behavior for the COVID-19 virus transmission in radiotherapy units. In order to overcome this, the ONCORAD radiotherapy units worked on total dematerialization of the paper patient file, within 3 weeks. The methodology is based on a quality approch. This work has led to a convincing improvement in the management of risks a priori and a smoother patient care workflow.PMID:34215522 | DOI:10.1016/j.canrad.2021.06.005 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - July 3, 2021 Category: Cancer & Oncology Authors: C Boutry A Sors K Meynard M D Zarate M S Couderc M V Delmas P Dudouet Source Type: research

Source blocking in HDR brachytherapy: Practical situation and experience feedback at the Eug ène Marquis-Rennes
This article describes the experience feedback from this training by brachytherapy technicians.PMID:34187715 | DOI:10.1016/j.canrad.2021.06.003 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - June 30, 2021 Category: Cancer & Oncology Authors: H Guehenneux C Geffroy E Leroy Source Type: research

Source blocking in HDR brachytherapy: Practical situation and experience feedback at the Eug ène Marquis-Rennes
This article describes the experience feedback from this training by brachytherapy technicians.PMID:34187715 | DOI:10.1016/j.canrad.2021.06.003 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - June 30, 2021 Category: Cancer & Oncology Authors: H Guehenneux C Geffroy E Leroy Source Type: research

Source blocking in HDR brachytherapy: Practical situation and experience feedback at the Eug ène Marquis-Rennes
This article describes the experience feedback from this training by brachytherapy technicians.PMID:34187715 | DOI:10.1016/j.canrad.2021.06.003 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - June 30, 2021 Category: Cancer & Oncology Authors: H Guehenneux C Geffroy E Leroy Source Type: research