Concurrent radiation therapy and dual HER2 blockade in breast cancer: Assessment of toxicity
CONCLUSION: The concurrent use of radiotherapy, pertuzumab and trastuzumab is feasible with good tolerance. Larger prospective data with longer follow-up is needed to confirm these results.PMID:33771453 | DOI:10.1016/j.canrad.2020.06.037 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 27, 2021 Category: Cancer & Oncology Authors: S Ben Dhia P Loap D Loirat A Vincent-Salomon K Cao L Escalup A Fourquet Y Kirova Source Type: research

Concurrent radiation therapy and dual HER2 blockade in breast cancer: Assessment of toxicity
CONCLUSION: The concurrent use of radiotherapy, pertuzumab and trastuzumab is feasible with good tolerance. Larger prospective data with longer follow-up is needed to confirm these results.PMID:33771453 | DOI:10.1016/j.canrad.2020.06.037 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 27, 2021 Category: Cancer & Oncology Authors: S Ben Dhia P Loap D Loirat A Vincent-Salomon K Cao L Escalup A Fourquet Y Kirova Source Type: research

Concurrent radiation therapy and dual HER2 blockade in breast cancer: Assessment of toxicity
CONCLUSION: The concurrent use of radiotherapy, pertuzumab and trastuzumab is feasible with good tolerance. Larger prospective data with longer follow-up is needed to confirm these results.PMID:33771453 | DOI:10.1016/j.canrad.2020.06.037 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 27, 2021 Category: Cancer & Oncology Authors: S Ben Dhia P Loap D Loirat A Vincent-Salomon K Cao L Escalup A Fourquet Y Kirova Source Type: research

Concurrent radiation therapy and dual HER2 blockade in breast cancer: Assessment of toxicity
CONCLUSION: The concurrent use of radiotherapy, pertuzumab and trastuzumab is feasible with good tolerance. Larger prospective data with longer follow-up is needed to confirm these results.PMID:33771453 | DOI:10.1016/j.canrad.2020.06.037 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 27, 2021 Category: Cancer & Oncology Authors: S Ben Dhia P Loap D Loirat A Vincent-Salomon K Cao L Escalup A Fourquet Y Kirova Source Type: research

Perineal recurrence of prostate cancer along a brachytherapy needle track: A case report
Cancer Radiother. 2021 Mar 21:S1278-3218(20)30325-5. doi: 10.1016/j.canrad.2020.06.027. Online ahead of print.ABSTRACTMetastatic recurrence in an atypical site, such as the perineum, can occur after prostatectomy, cryotherapy, or brachytherapy, but is uncommon. To our knowledge, this is only the third case of perineal recurrence of prostatic cancer along a low dose rate brachytherapy needle track. A 64-year-old man was referred to an urologist with an increased PSA of 6.9ng/mL in December 2008. There were no urinary symptoms. Prostatic biopsies revealed a Gleason 6 adenocarcinoma (3+3), and he was treated with low dose rat...
Source: Cancer Radiotherapie - March 25, 2021 Category: Cancer & Oncology Authors: I Sidibe M Le Blanc-Onfroy G Delpon E Rio M Crepel M Lacour J Rigaud S Cazin S Supiot Source Type: research

Impact of the method chosen for the analysis of recurrences after radiotherapy for head and neck cancers: volume-based, point-based and combined methods
Cancer Radiother. 2021 Mar 21:S1278-3218(20)30320-6. doi: 10.1016/j.canrad.2020.05.021. Online ahead of print.ABSTRACTIntensity modulated radiation therapy for head and neck is a complex technique. Inappropriate delineation and/or dose distribution can lead to recurrences. Analysis of these recurrences should lead to improve clinical practice. For several years, different methods of analysis have been described. The purpose of this review is to describe these different methods and to discuss their advantages and limitations. The first published methods used a volume-based approach studying the entire volume of recurrence a...
Source: Cancer Radiotherapie - March 25, 2021 Category: Cancer & Oncology Authors: C Mione F Martin J Miroir J Moreau N Saroul N Pham Dang R Bellini M Lapeyre J Biau Source Type: research

Perineal recurrence of prostate cancer along a brachytherapy needle track: A case report
Cancer Radiother. 2021 Mar 21:S1278-3218(20)30325-5. doi: 10.1016/j.canrad.2020.06.027. Online ahead of print.ABSTRACTMetastatic recurrence in an atypical site, such as the perineum, can occur after prostatectomy, cryotherapy, or brachytherapy, but is uncommon. To our knowledge, this is only the third case of perineal recurrence of prostatic cancer along a low dose rate brachytherapy needle track. A 64-year-old man was referred to an urologist with an increased PSA of 6.9ng/mL in December 2008. There were no urinary symptoms. Prostatic biopsies revealed a Gleason 6 adenocarcinoma (3+3), and he was treated with low dose rat...
Source: Cancer Radiotherapie - March 25, 2021 Category: Cancer & Oncology Authors: I Sidibe M Le Blanc-Onfroy G Delpon E Rio M Crepel M Lacour J Rigaud S Cazin S Supiot Source Type: research

Impact of the method chosen for the analysis of recurrences after radiotherapy for head and neck cancers: volume-based, point-based and combined methods
Cancer Radiother. 2021 Mar 21:S1278-3218(20)30320-6. doi: 10.1016/j.canrad.2020.05.021. Online ahead of print.ABSTRACTIntensity modulated radiation therapy for head and neck is a complex technique. Inappropriate delineation and/or dose distribution can lead to recurrences. Analysis of these recurrences should lead to improve clinical practice. For several years, different methods of analysis have been described. The purpose of this review is to describe these different methods and to discuss their advantages and limitations. The first published methods used a volume-based approach studying the entire volume of recurrence a...
Source: Cancer Radiotherapie - March 25, 2021 Category: Cancer & Oncology Authors: C Mione F Martin J Miroir J Moreau N Saroul N Pham Dang R Bellini M Lapeyre J Biau Source Type: research

Perineal recurrence of prostate cancer along a brachytherapy needle track: A case report
Cancer Radiother. 2021 Mar 21:S1278-3218(20)30325-5. doi: 10.1016/j.canrad.2020.06.027. Online ahead of print.ABSTRACTMetastatic recurrence in an atypical site, such as the perineum, can occur after prostatectomy, cryotherapy, or brachytherapy, but is uncommon. To our knowledge, this is only the third case of perineal recurrence of prostatic cancer along a low dose rate brachytherapy needle track. A 64-year-old man was referred to an urologist with an increased PSA of 6.9ng/mL in December 2008. There were no urinary symptoms. Prostatic biopsies revealed a Gleason 6 adenocarcinoma (3+3), and he was treated with low dose rat...
Source: Cancer Radiotherapie - March 25, 2021 Category: Cancer & Oncology Authors: I Sidibe M Le Blanc-Onfroy G Delpon E Rio M Crepel M Lacour J Rigaud S Cazin S Supiot Source Type: research

Impact of the method chosen for the analysis of recurrences after radiotherapy for head and neck cancers: volume-based, point-based and combined methods
Cancer Radiother. 2021 Mar 21:S1278-3218(20)30320-6. doi: 10.1016/j.canrad.2020.05.021. Online ahead of print.ABSTRACTIntensity modulated radiation therapy for head and neck is a complex technique. Inappropriate delineation and/or dose distribution can lead to recurrences. Analysis of these recurrences should lead to improve clinical practice. For several years, different methods of analysis have been described. The purpose of this review is to describe these different methods and to discuss their advantages and limitations. The first published methods used a volume-based approach studying the entire volume of recurrence a...
Source: Cancer Radiotherapie - March 25, 2021 Category: Cancer & Oncology Authors: C Mione F Martin J Miroir J Moreau N Saroul N Pham Dang R Bellini M Lapeyre J Biau Source Type: research

Clinical outcome after CyberKnife ® radiosurgery re-irradiation for recurrent brain metastases
CONCLUSION: With acceptable toxicity, SRS re-irradiation for LR BM showed a favourable rate for LC and OS and reported better OS for the female gender, a patient undergoing first brain radiation with SRS, tumour volume ≤12cc, and RPA-I. This result needs to be further evaluated in future clinical studies.PMID:33752961 | DOI:10.1016/j.canrad.2021.02.003 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 23, 2021 Category: Cancer & Oncology Authors: T Berber V Raturi F Aksaray H Hojo T Fujisawa H Ohyoshi Source Type: research

Clinical outcome after CyberKnife ® radiosurgery re-irradiation for recurrent brain metastases
CONCLUSION: With acceptable toxicity, SRS re-irradiation for LR BM showed a favourable rate for LC and OS and reported better OS for the female gender, a patient undergoing first brain radiation with SRS, tumour volume ≤12cc, and RPA-I. This result needs to be further evaluated in future clinical studies.PMID:33752961 | DOI:10.1016/j.canrad.2021.02.003 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 23, 2021 Category: Cancer & Oncology Authors: T Berber V Raturi F Aksaray H Hojo T Fujisawa H Ohyoshi Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

Early side effects of radiation treatment for head and neck cancer
In conclusion, radiation treatment for the head and neck cancer causes significant early side effects. Many of these side effects present difficult challenges to the patients. Their recognition and treatment can significantly improve the patients' health, long-term survival and quality of life. The review provides information that can assist head and cancer survivors deal with radiation side effects.PMID:33685809 | DOI:10.1016/j.canrad.2021.02.001 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 9, 2021 Category: Cancer & Oncology Authors: I Brook Source Type: research

A new model outperforming RPA and DS-GPA scores for individualized survival prediction of patients following whole brain irradiation for brain metastasis
CONCLUSION: Our model provides individualized estimates of survival for poor prognosis patients undergoing WBRT, outperforming actual scoring systems.PMID:33678525 | DOI:10.1016/j.canrad.2021.02.002 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 8, 2021 Category: Cancer & Oncology Authors: C Marchand-Crety J Riverain Y Drouet F Felici C L Jeandidier J Thariat S Servagi-Vernat Source Type: research

A new model outperforming RPA and DS-GPA scores for individualized survival prediction of patients following whole brain irradiation for brain metastasis
CONCLUSION: Our model provides individualized estimates of survival for poor prognosis patients undergoing WBRT, outperforming actual scoring systems.PMID:33678525 | DOI:10.1016/j.canrad.2021.02.002 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 8, 2021 Category: Cancer & Oncology Authors: C Marchand-Crety J Riverain Y Drouet F Felici C L Jeandidier J Thariat S Servagi-Vernat Source Type: research

The safety and efficacy of Cyberknife ® for thymic malignancy
CONCLUSION: CK treatment resulted in good outcomes, particularly local control, with minimal side effects, in highly selected patients with primary and recurring thymic tumours. More studies with larger sample are needed.PMID:33676829 | DOI:10.1016/j.canrad.2020.06.026 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 7, 2021 Category: Cancer & Oncology Authors: C Xu J Sun W Zhang Z Yuan J Wang Source Type: research

Clinical practice of breast cancer protontherapy: A single-centre experience from selection to treatment
CONCLUSION: Despite dosimetric advantages and excellent clinical tolerance, lack of availability of protontherapy machines currently limits wider implementation of breast protontherapy.PMID:33676830 | DOI:10.1016/j.canrad.2021.01.005 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - March 7, 2021 Category: Cancer & Oncology Authors: P Loap A Beddok K I Cao F Goudjil A Fourquet R Dendale Y Kirova Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Impact of field number and beam angle on ERE for lung stereotactic body radiotherapy with 1.5T MR-Linac
CONCLUSION: The plan quality can be significantly changed by the presence of a 1.5T TMF for lung SBRT with MR-Linac. The selection of optimal fields number and beam angle can substantially reduce or even eliminate these changes, without deteriorating overall plan quality.PMID:33622638 | DOI:10.1016/j.canrad.2021.01.006 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 24, 2021 Category: Cancer & Oncology Authors: S Ding H Liu B Wang Y Li R Li B Liu Y Xia X Huang Source Type: research

Long-term outcome of Stereotactic Body Radiation Therapy for patient with unresectable liver metastases from colorectal cancer
CONCLUSION: Stereotactic body radiation therapy is an effective and well-tolerated treatment that allow high LC for liver metastases from colorectal cancer during the first two years. A prescription dose of 45Gy in 3 fractions to the 80% isodose line with a risk adapted schedule to respect Organ At Risk constraints allows a low rate of toxicity.PMID:33618909 | DOI:10.1016/j.canrad.2021.01.004 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 23, 2021 Category: Cancer & Oncology Authors: J F Py J Salleron F Courrech V Beckendorf V Crois é-Laurent D Peiffert G Vogin A S Dietmann Source Type: research

Long-term outcome of Stereotactic Body Radiation Therapy for patient with unresectable liver metastases from colorectal cancer
CONCLUSION: Stereotactic body radiation therapy is an effective and well-tolerated treatment that allow high LC for liver metastases from colorectal cancer during the first two years. A prescription dose of 45Gy in 3 fractions to the 80% isodose line with a risk adapted schedule to respect Organ At Risk constraints allows a low rate of toxicity.PMID:33618909 | DOI:10.1016/j.canrad.2021.01.004 (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 23, 2021 Category: Cancer & Oncology Authors: J F Py J Salleron F Courrech V Beckendorf V Crois é-Laurent D Peiffert G Vogin A S Dietmann Source Type: research

Ablative radiosurgery for cardiac arrhythmias  - A systematic review
Cancer Radiother. 2021 Feb 13:S1278-3218(21)00025-1. doi: 10.1016/j.canrad.2021.01.009. Online ahead of print.ABSTRACTStereotactic body radiotherapy (SBRT) is a high precision technique that is commonly used for malignant lesions in lung, liver, pancreas and spine. Recent reports suggest promise in use of SBRT as a tool in atrial and ventricular cardiac arrhythmias. The present systematic review deals with the use of SBRT technology for this novel indication. A PubMed search was done for articles published between 1990 and 2020. All original articles, case reports, case series of treated patients were included in the analy...
Source: Cancer Radiotherapie - February 16, 2021 Category: Cancer & Oncology Authors: A Munshi Source Type: research

Ablative radiosurgery for cardiac arrhythmias  - A systematic review.
Ablative radiosurgery for cardiac arrhythmias - A systematic review. Cancer Radiother. 2021 Feb 13;: Authors: Munshi A Abstract Stereotactic body radiotherapy (SBRT) is a high precision technique that is commonly used for malignant lesions in lung, liver, pancreas and spine. Recent reports suggest promise in use of SBRT as a tool in atrial and ventricular cardiac arrhythmias. The present systematic review deals with the use of SBRT technology for this novel indication. A PubMed search was done for articles published between 1990 and 2020. All original articles, case reports, case series of t...
Source: Cancer Radiotherapie - February 13, 2021 Category: Cancer & Oncology Authors: Munshi A Tags: Cancer Radiother Source Type: research

[Proposal for the delineation of postoperative primary clinical target volumes in ethmoid cancers].
This article does not discuss the indications of external radiotherapy but specifies the volumes to be delineated if radiotherapy is considered. PMID: 33546996 [PubMed - as supplied by publisher] (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - February 2, 2021 Category: Cancer & Oncology Authors: Guillemin F, Miroir J, Piram L, Bellini R, Saroul N, Pham Dang N, Boisselier P, Bourhis J, Calugaru V, Coutte A, Graff P, Pointreau Y, Racadot S, Sun XS, Thariat J, Biau J, Lapeyre M Tags: Cancer Radiother Source Type: research

Angiosarcoma associated with radiation therapy after treatment of breast cancer. Retrospective study on ten years.
CONCLUSION: The median latency was 10 (4-24) years, the incidence of AAR in the East Belgian area was 0.09% of the patients irradiated on the same period. Patients were treated by surgery with wide local excision with or without reconstructive surgery, without radiotherapy and chemotherapy treatment. Kaplan-Meier analysis showed median overall survival of 61.8 months, patient survival of 55.6% at one year and 29.6% at five years. With the constant progress of medicine and its technologies, it would be possible to limit the occurrence of AAR or to diagnose it at an earlier stage. PMID: 33487559 [PubMed - as supplied by...
Source: Cancer Radiotherapie - January 21, 2021 Category: Cancer & Oncology Authors: Verdin V, Mattart L, Cusumano PG, De Hertogh O, De Meester C, Francart D, Kirova YM, Nelissen X, Sacino F, Vanderick J, Weerts J, Markiewicz S Tags: Cancer Radiother Source Type: research

Brachytherapy boost (BT-boost) or stereotactic body radiation therapy boost (SBRT-boost) for high-risk prostate cancer (HR-PCa).
Abstract Systematic review for the treatment of high-risk prostate cancer (HR-PCa, D'Amico classification risk system) with external body radiation therapy (EBRT)+brachytherapy-boost (BT-boost) or with EBRT+stereotactic body RT-boost (SBRT-boost). In March 2020, 391 English citations on PubMed matched with search terms "high risk prostate cancer boost". Respectively 9 and 48 prospective and retrospective studies were on BT-boost and 7 retrospective studies were on SBRT-boost. Two SBRT-boost trials were prospective. Only one study (ASCENDE-RT) directly compared the gold standard treatment [dose-escalation...
Source: Cancer Radiotherapie - January 18, 2021 Category: Cancer & Oncology Authors: Peyraga G, Lizee T, Khalifa J, Blais E, Mauriange-Turpin G, Supiot S, Krhili S, Tremolieres P, Graff-Cailleaud P Tags: Cancer Radiother Source Type: research

[Application of the « Junior Doctor » status in Radiation Oncology].
[Application of the « Junior Doctor » status in Radiation Oncology]. Cancer Radiother. 2021 Jan 15;: Authors: Bourbonne V, Michalet M, Lopez H, Pradier O, Spano JP, Giraud P Abstract Introduced in 2017, the reform of the 3rd cycle has modified the organization of the residency in all specialties, and in particular radiation oncology. The residency was thus divided into 3 phases with increasing knowledge and responsibilities. The latter, carried out under the status of "junior doctor", created and defined by decree n°2018-571 of July 3, 2018 and the decree of January...
Source: Cancer Radiotherapie - January 15, 2021 Category: Cancer & Oncology Authors: Bourbonne V, Michalet M, Lopez H, Pradier O, Spano JP, Giraud P Tags: Cancer Radiother Source Type: research

I125 irradiation stent for treatment of hepatocellular carcinoma with portal vein thrombosis: A meta-analysis.
Abstract PURPOSE: A meta-analysis aimed to systematically evaluate the safety and efficiency of I125 irradiation stent placement for patients with hepatocellular carcinoma (HCC) combined with portal vein tumor thrombosis (PVTT). MATERIALS AND METHODS: The Cochrane library, PubMed/Medline, EMBASE, CNKI, Wanfang Data and CQVIP were systematically screened out from the earliest to December 2019. The qualities of all included studies were assessed. The primary endpoints were the 6-month, 12-month stent cumulative patency rate and 6-month, 12-month, 24-month overall survival rate while the secondary endpoints were...
Source: Cancer Radiotherapie - January 14, 2021 Category: Cancer & Oncology Authors: Li S, Guo JH, Lu J, Wang C, Wu H, Wang H, Zha J, Fan R Tags: Cancer Radiother Source Type: research

Stereotactic radiotherapy for hepatocellular carcinoma induced by hepatitis C and the relationships of changes in carbohydrate antigen 19-9 with AFP and PIVKA-II.
CONCLUSIONS: This is the first investigation of changes in CA 19-9 levels after SBRT for HCC induced by hepatitis C. Characteristic changes in CA 19-9, AFP, and PIVKA-II levels were observed as responses after treatment. As for its correlations with tumour markers, the acute responses of PIVKA-II tended to be slower than those of CA 19-9 and AFP. Although the sample size was small, our findings raise the possibility that measuring these 3 biomarkers after SBRT may be useful for monitoring patients for HCC recurrence. PMID: 33455875 [PubMed - as supplied by publisher] (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - January 14, 2021 Category: Cancer & Oncology Authors: Maebayashi T, Ishibashi N, Aizawa T, Sakaguchi M, Okada M Tags: Cancer Radiother Source Type: research

Evaluation of margins in pelvic lymph nodes and prostate radiotherapy and the impact of bladder and rectum on prostate position.
CONCLUSIONS: We recommend CTV to PTV margins of 8mm, 6mm and 9mm in AP, ML and SI directions for prostate. And, we suggest 4mm and 5mm for external and common iliac vessels respectively. We also prefer registration based on bony landmarks to minimize bowel irradiation. More CBCT scans should be performed during the first 3weeks and especially the first week to check rectum volume. PMID: 33454191 [PubMed - as supplied by publisher] (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - January 13, 2021 Category: Cancer & Oncology Authors: Marnouche EA, Hadadi K, Abdelhak M, Benlemlih M, Hommadi M, Zaghba N, Andaloussi Saghir K, Elmarjany M, Sifat H, Mansouri H Tags: Cancer Radiother Source Type: research

Radio-induced esophageal motility disorders: An unrecognized diagnosis.
CONCLUSION: EMD should be suspected in patients with a history of cervical or thoracic RT in case of upper GI symptoms with normal endoscopy. In these particular patients, a manometric diagnosis that can explain their symptoms is of particular importance to limit anxiety linked to unexplained troubles. PMID: 33454192 [PubMed - as supplied by publisher] (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - January 13, 2021 Category: Cancer & Oncology Authors: Vitton V, Andrianjafy C, Luciano L, Gonzalez JM, Padovani L Tags: Cancer Radiother Source Type: research

[Low-dose irradiation of non-malignant diseases: Did we throw the baby out with the bathwater?]
Abstract The irradiation of non-malignant diseases, essentially for anti-inflammatory purpose, have been largely proposed and performed worldwide until the 1970-80s. At that time, the better assessment of the radio-induced malignancies, essentially in children and young patients, as well as the efficacy of the new anti-inflammatory drugs (steroids and non-steroids), led to the almost disappearance of those techniques, at least in France. In contrast, our German colleagues are still going on treating about 50,000 patients per year for non-malignant (more or less severe) diseases. After a short historical overv...
Source: Cancer Radiotherapie - January 12, 2021 Category: Cancer & Oncology Authors: Cosset JM, Deutsch E Tags: Cancer Radiother Source Type: research

Study of the predictors for radiation pneumonitis in patient with non-small cell lung cancer received radiotherapy after pneumonectomy.
Abstract PURPOSE: To identify the valuable predictors of grade≥2 radiation pneumonitis (RP) in patient treated with radiotherapy after pneumonectomy for non-small cell lung cancer (NSCLC); and to construct a nomogram predicting the incidence of grade≥2 RP in such patients. PATIENTS AND METHODS: We reviewed 82 patients with NSCLC received radiotherapy after pneumonectomy from 2008 to 2018. The endpoint was grade≥2 RP. Univariate and multivariate regression analysis were conducted to evaluate significant factors of grade≥2 RP. Receiver operating characteristic (ROC) curve was used to establish optim...
Source: Cancer Radiotherapie - January 11, 2021 Category: Cancer & Oncology Authors: Yu JH, Wang CL, Liu Y, Wang JM, Lv CX, Liu J, Zhang Q, Fu XL, Cai XW Tags: Cancer Radiother Source Type: research

[Risk management and (health) crisis: How to assess the impact of changing a prescription over time in radiotherapy].
PMID: 33446420 [PubMed - as supplied by publisher] (Source: Cancer Radiotherapie)
Source: Cancer Radiotherapie - January 11, 2021 Category: Cancer & Oncology Authors: Colin G, Coucke P Tags: Cancer Radiother Source Type: research