Equitable Representation of Pregnant and Lactating Women in Clinical Research: A Historical Review and Critical Analysis of Proposed Legislation
Am J Perinatol DOI: 10.1055/a-2308-3580A long history of policymaking and regulation constructed for the purpose of ensuring adequate fetal and infant protections has inadvertently sanctioned the widespread exclusion of pregnant and lactating patients from biomedical research, leaving a paucity of high quality data necessary for clinical decision-making. Although well-intended, the regulatory classification of pregnant women as “vulnerable,” in conjunction with burdensome enrollment criteria and other factors weighing against broad inclusion, have ultimately placed the health and safety of these women and their babies ...
Source: American Journal of Perinatology - May 7, 2024 Category: Perinatology & Neonatology Authors: Woods, Richard H. Tags: Review Article Source Type: research

Is the Risk of Intrahepatic Cholestasis Increased with Supplemental Progesterone?
Conclusion Contrary to recent evidence, no association was seen with the use of supplemental progesterone. It is possible that the associated risk with supplemental progesterone is dependent on medication formulation or route of administration. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 7, 2024 Category: Perinatology & Neonatology Authors: Rohn, Matthew C.H. Vignali, Lindsey Reeder, Isabel Khosravian, Kiana Petersen, Scott Tags: Original Article Source Type: research

Therapeutic Hypothermia for Neonatal Hypoxic –Ischemic Encephalopathy: Reducing Variability in Practice through a Collaborative Telemedicine Initiative
Conclusion This study shows that implementing a tele-educational program in neonatal neurocritical care is feasible and may decrease variability in the delivery of care to patients with HIE treated with TH. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 7, 2024 Category: Perinatology & Neonatology Authors: Leandro, Danieli M.K. Variane, Gabriel F.T. Dahlen, Alex Pietrobom, Rafaela F.R. de Castro, Jessica A.R.R. Rodrigues, Daniela P. Magalh ães, Mauricio Mimica, Marcelo J. Van Meurs, Krisa P. Chock, Valerie Y. Tags: Original Article Source Type: research

Management, Utilization, and Outcomes of Preterm Labor in an Integrated Health Care System
Conclusion This study demonstrates that positive fFN results were associated with an increased odds of sPTB, RDS, and NICU admission and the association with sPTB was inversely proportional to CL. Additionally, negative fFN results were associated with decreased odds of sPTB, RDS, and NICU admissions. fFN testing may predict these and other sPTB-related adverse outcomes hence its utility should be explored further. Moreover, fFN testing has some cost savings over TVUS. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of ...
Source: American Journal of Perinatology - May 7, 2024 Category: Perinatology & Neonatology Authors: Getahun, Darios Sacks, David A. Shi, Jiaxiao Xie, Fagen Khadka, Nehaa Chiu, Vicki Y. Mensah, Nana A. Avila, Chantal C. Yeh, Meiyu Kawatkar, Aniket A. Ruma, Michael S. Joyce, Derek Fassett, Michael J. Tags: Original Article Source Type: research

Cerclage plus Adjuvant Vaginal Progesterone for Preterm Birth Prevention in Patients with a Short or Dilated Cervix without Prior Preterm Birth
Conclusion While not statistically significant, the risk of sPTB was lower at all gestational ages studied in patients treated with dual therapy compared with monotherapy. Dual therapy was associated with longer pregnancy latency and greater gestational age at delivery compared with monotherapy. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 2, 2024 Category: Perinatology & Neonatology Authors: Hart, Jessica M. Macharia, Annliz Modest, Anna M. Johnson, Katherine M. Lauring, Julianne Nicasio, Erica Hacker, Michele R. Spiel, Melissa H. Tags: SMFM Fellows Research Series Source Type: research

Correlating Severity of Pulmonary Hypertension by Echocardiogram with Mortality in Premature Infants with Bronchopulmonary Dysplasia
Conclusion Using predefined criteria for PH, premature infants with BPD can be stratified into PH severity categories. Patients diagnosed with severe PH by echocardiogram have significantly reduced survival. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 2, 2024 Category: Perinatology & Neonatology Authors: Torok, Rachel D. Gardner, Robert A. Barker, Piers C.A. McCrary, Andrew W. Li, Jennifer S. Hornik, Christoph P. Laughon, Matthew M. Jackson, Wesley M. Tags: Original Article Source Type: research

The Impact on Birth Outcomes of Sonographic Fetal Weight Estimation in Neonatal Macrosomia
Conclusion Larger EFW increased CD risk among pregnancies with actual neonatal macrosomia. Antenatally suspected macrosomia might alter labor management due to concerns for potential complications, especially when associated with primiparity, diabetes mellitus, or maternal obesity. The increase in the CD rate did not show an association with improved maternal and neonatal outcomes. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 2, 2024 Category: Perinatology & Neonatology Authors: Sgayer, Inshirah Nskovica, Karina Murkhovskyi, Iuliia Shqara, Raneen Abu Bilyk, Artyom Lowenstein, Lior Wolf, Maya Frank Tags: Original Article Source Type: research

Identifying ChatGPT-written Patient Education Materials Using Text Analysis and Readability
Conclusion As ChatGPT is more widely integrated into medicine, it will be important for health care stakeholders to have tools to separate originally written documents from those generated by AI. While more robust analyses may be required to determine the authenticity of articles written by complex AI technology in the future, simple grammatical analysis can accurately characterize current AI-generated texts with a high degree of sensitivity and specificity. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents ...
Source: American Journal of Perinatology - May 2, 2024 Category: Perinatology & Neonatology Authors: Monje, Silas Ulene, Sophie Gimovsky, Alexis C. Tags: Original Article Source Type: research

Erratum: Maternal Hemodynamics from Preconception to Delivery: Research and Potential Diagnostic and Therapeutic Implications: Position Statement by Italian Association of Pre-Eclampsia and Italian Society of Perinatal Medicine
Am J Perinatol DOI: 10.1055/s-0044-1786746 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 2, 2024 Category: Perinatology & Neonatology Authors: Vasapollo, Barbara Zullino, Sara Novelli, Gian Paolo Farsetti, Daniele Ottanelli, Serena Clemenza, Sara Micaglio, Massimo Ferrazzi, Enrico Di Martino, Daniela Denis Ghi, Tullio Di Pasquo, Elvira Orabona, Rossana Corbella, Paola Frigo, Maria Grazia Prefumo Tags: Erratum Source Type: research

Essentials of Point-of-Care Ultrasound Coding and Billing at the Neonatal Intensive Care Unit Setting in the United States
This article describes the coding terminology and billing process especially those relevant to neonatal POCUS. We elucidate considerations for neonatal POCUS billing framework and workflow integration. Directions on image storage and supporting documentation to facilitate efficient reimbursement, compliance with billing regulations, and appeal to insurance claim denial are discussed. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 2, 2024 Category: Perinatology & Neonatology Authors: Chan, Belinda Mnyavanu, Natalie Bhombal, Shazia Fraga, Mar ía V. Groves, Alan M. Marshall, Stephanie Mukthapuram, Shanmukha Singh, Yogen Tags: Clinical Opinion Source Type: research

Erratum: Workforce Characteristics of Early Career Neonatologists and Comparison of Practice Sites
Am J Perinatol DOI: 10.1055/s-0044-1786747 Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 1, 2024 Category: Perinatology & Neonatology Authors: Nestander, Matt Day, Colby Lucke, Ashley Gautam, Shiva Horowitz, Eric Bernstein, Sarah M. Bhatia, Anisha Tags: Erratum Source Type: research

A Prospective Study of Lactate Levels in Uncomplicated Spontaneous and Induced Labor
Conclusion Lactate levels increase significantly once a patient reaches complete cervical dilation within 30 minutes of pushing. This increase is more pronounced, although significantly, in patients with chorioamnionitis. As sepsis is one of the leading causes of maternal morbidity and mortality, this pilot study is relevant for providers to see the natural course of lactate levels in labor. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 30, 2024 Category: Perinatology & Neonatology Authors: Kleinmann, Whitney Zofkie, Amanda McIntire, Donald Adhikari, Emily H. Tags: SMFM Fellows Research Series Source Type: research

The Diagnostic Yield of Chromosomal Microarray Analysis in Third-Trimester Fetal Abnormalities
Conclusion The 6.2% detection rate of significant CNVs in late-onset fetal anomalies confirms the value of CMA in third-trimester amniocentesis. The findings underscore the necessity of CMA for detecting CNVs potentially overlooked by NIPT and emphasize the importance of thorough genetic counseling. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 30, 2024 Category: Perinatology & Neonatology Authors: Elron, Eyal Maya, Idit Shefer-Averbuch, Noa Kahana, Sarit Matar, Reut Klein, Kochav Agmon-Fishman, Ifat Gurevitch, Merav Basel-Salmon, Lina Levy, Michal Tags: Original Article Source Type: research

Periviable Premature Rupture of Membranes —Maternal and Neonatal Risks: A Systematic Review and Meta-analysis
Conclusion Women who undergo expectant management following periviable rupture of membranes experience significantly increased risks of sepsis, chorioamnionitis, and laparotomy. Overall, 39% of neonates survive to discharge. Knowledge of these risks is critical to counseling patients with this diagnosis. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 29, 2024 Category: Perinatology & Neonatology Authors: Saucedo, Alexander M. Calvert, Chase Chiem, Adrian Groves, Alan Ghartey, Kobina Cahill, Alison G. Harper, Lorie M. Tags: SMFM Fellows Research Series Source Type: research

Clinical and Growth Correlates of Retinopathy of Prematurity in Preterm Infants with Surgical Necrotizing Enterocolitis and Intestinal Perforation
Conclusion Infants who develop severe ROP following surgical NEC/SIP are likely to be younger, smaller, have been exposed to more O2, develop AKI, and grow poorly compared with those did not develop severe ROP. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 26, 2024 Category: Perinatology & Neonatology Authors: Garg, Parvesh M. Riddick, Robin A. Ansari, Md A.Y. Meilstrup, Asha C. Zepponi, David Smith, Andrea Mungan, Nils Shenberger, Jeffrey Hillegass, William B. Garg, Padma P. Tags: Original Article Source Type: research