Resident Operative Vaginal Delivery Volume after Educational Curriculum Implementation
Am J Perinatol DOI: 10.1055/s-0040-1710543 Objective The percentage of operative vaginal deliveries (OVDs) in the United States has sharply declined. In May 2016, our institution's obstetrics and gynecology (OB/GYN) residency program implemented a twice-yearly OVD curriculum consisting of didactics and simulation. We sought to evaluate the impact of this curriculum. Study Design We performed a retrospective cohort study of all deliveries at our institution from July 2011 to May 2018. Deliveries were evaluated quarterly for the pre- (July 2011–April 2016) and postcurriculum (July 2016–May 2018) p...
Source: American Journal of Perinatology - May 26, 2020 Category: Perinatology & Neonatology Authors: Becker, David A. Blanchard, Christina T. Szychowski, Jeff M. Rogers, Sharee L. Brumfield, Cynthia G. Subramaniam, Akila Tags: SMFM Fellowship Series Article Source Type: research

Validation of Postpartum Hemorrhage Admission Risk Factor Stratification in a Large Obstetrics Population
Conclusion We found that the CMQCC admission risk assessment criteria stratified women by increasing rates of severe postpartum hemorrhage in our sample, which enables early preparation for many postpartum hemorrhages. However, the CMQCC risk factors missed a substantial proportion of postpartum hemorrhages. Efforts to improve postpartum hemorrhage risk assessment using present-on-admission risk factors should consider inclusion of other nonobstetrical factors. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract&nbs...
Source: American Journal of Perinatology - May 26, 2020 Category: Perinatology & Neonatology Authors: Ruppel, Halley Liu, Vincent X. Gupta, Neeru R. Soltesz, Lauren Escobar, Gabriel J. Tags: Original Article Source Type: research

The Postpartum Hemorrhage Patient Safety Bundle Implementation at a Single Institution: Successes, Failures, and Lessons Learned
Conclusion The postpartum hemorrhage patient safety bundle provided concrete individual elements, which overall improved the success of a stratified program implementation. Multiple deficiencies in acceptability and sustainability were uncovered during our process, particularly concerns about quantitative blood loss implementation and team communication skills. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 26, 2020 Category: Perinatology & Neonatology Authors: Duzyj, Christina M. Boyle, Carla Mahoney, Kathleen Johnson, Anna Rose Ogot, Grace Ayers, Charletta Tags: Original Article Source Type: research

Erratum: Near-Infrared Spectroscopy: A Tool for Diagnosing Necrotizing Enterocolitis at Onset of Symptoms in Preterm Neonates with Acute Gastrointestinal Symptoms?
Am J Perinatol DOI: 10.1055/s-0040-1712478 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 26, 2020 Category: Perinatology & Neonatology Authors: Bouhellec, Julia Le Prodhomme, Olivier Mura, Thibault Jacquot, Aur élien Combes, Cl émentine Gamon, Lucie Durand, Sabine Filleron, Anne Cambonie, Gilles Tags: Erratum Source Type: research

Bevacizumab for Retinopathy of Prematurity: 2-Year Neurodevelopmental Follow-up
This study aimed to determine whether infants who were treated with intravitreal bevacizumab (IVB) for retinopathy of prematurity (ROP) were at higher risk of death or neurodevelopmental impairment (NDI) when compared with infants who were not treated with IVB (Laser only). Study Design This retrospective study included 146 infants born from 2009 through 2016 with a birth weight (BW)
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Zayek, Michael Parker, Kaitlyn Rydzewska, Monika Rifai, Aref Bhat, Ramachandra Eyal, Fabien Tags: Original Article Source Type: research

Ongoing Supplementation of Probiotics to Cesarean-Born Neonates during the First Month of Life may Impact the Gut Microbial
Conclusion This study showed that probiotics supplementation to cesarean-born neonates since birth might impact the diversity and function of gut microbiota. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Yang, Wenqing Tian, Liang Luo, Jiao Yu, Jialin Tags: Original Article Source Type: research

Is Group B Streptococcus Colonization Associated with Maternal Peripartum Infection in an Era of Routine Prophylaxis?
Conclusion In contrast to historical data, GBS colonization was associated with lower odds of chorioamnionitis in an era of routine GBS screening and prophylaxis. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Venkatesh, Kartik K. Vladutiu, Catherine J. Glover, Angelica V. Strauss, Robert A. Stringer, Jeffrey S.A. Stamilio, David M. Hughes, Brenna Dotters-Katz, Sarah Tags: Original Article Source Type: research

Evaluation of the Prognostic Value of the sFlt-1/PlGF Ratio in Early-Onset Preeclampsia
Am J Perinatol DOI: 10.1055/s-0040-1709696 Objective Increased expression of soluble fms-like tyrosine kinase 1 (sFlt-1), associated with a decrease in placental growth factor (PlGF), plays a key role in the pathogenesis of preeclampsia (PE). We evaluated the prognostic value of the sFlt-1/PlGF ratio for the onset of adverse maternofetal outcomes (AMFO) in case of early-onset PE with attempted expectant management. Study Design From October 2016 through November 2018, all singleton pregnancies complicated by early-onset PE (before 34 weeks of gestation) were included in a cohort study. The plasma levels of ...
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Tasta, Oriane Parant, Olivier Hamdi, Safouane M. Allouche, Mickael Vayssiere, Christophe Guerby, Paul Tags: Original Article Source Type: research

The Association between Shirodkar Cerclage and Preterm Premature Rupture of Membranes in Singleton Pregnancies
Conclusion Cerclage does not increase the risk of preterm premature rupture of membranes prior to 34 weeks compared with other women at increased risk of preterm birth. The observed association between cerclage and preterm premature rupture of membranes is likely due to underlying risk factors and not the cerclage itself. The risk of preterm premature rupture of membranes prior to 34 weeks in women with cerclage is 10% or less and does not appear to differ based on cerclage indication. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of con...
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Muniz Rodriguez, Alberto Pastor, Andrew Fox, Nathan S. Tags: Original Article Source Type: research

Mucins and Tight Junctions are Severely Altered in Necrotizing Enterocolitis Neonates
Conclusion Mucins and tight junctions are severely altered in NEC neonates. This finding might provide clues for rupture of the intestinal barrier. Further research is needed to investigate the gene expression as well as the exact mechanisms behind these changes. This will help us better understand the role of the intestinal barrier in NEC. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Liu, Dong Xu, Yanzhen Feng, Jinxing Yu, Jialin Huang, Jinjie Li, Zhiguang Tags: Original Article Source Type: research

Antepartum Hemorrhage and Outcome of Very Low Birth Weight, Very Preterm Infants: A Population-Based Study
Am J Perinatol DOI: 10.1055/s-0040-1710353 Objective We aimed to determine the independent effect of maternal antepartum hemorrhage (APH) on mortality and major neonatal morbidities among very low birth weight (VLBW), very preterm infants. Study design A population-based cohort study of VLBW singleton infants born at 24 to 31 weeks of gestation between 1995 and 2016 was performed. Infants born with the following pregnancy associated complications were excluded: maternal hypertensive disorders, prolonged rupture of membranes, amnionitis, maternal diabetes, and small for gestational age. APH included hemorrha...
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Klinger, Gil Bromiker, Reuben Zaslavsky-Paltiel, Inna Sokolover, Nir Lerner-Geva, Liat Yogev, Yariv Reichman, Brian Tags: Original Article Source Type: research

ACC-AHA Diagnostic Criteria for Hypertension in Pregnancy Identifies Patients at Intermediate Risk of Adverse Outcomes
Am J Perinatol DOI: 10.1055/s-0040-1709465 Objective The aim of the study is to compare maternal and neonatal outcomes among patients who are normotensive, hypertensive by Stage I American College of Cardiology-American Heart Association (ACC-AHA) criteria, and hypertensive by American College of Obstetricians and Gynecologists (ACOG) criteria. Study Design Secondary analysis of a prospective first trimester cohort study between 2007 and 2010 at three institutions in Baltimore, MD, was conducted. Blood pressure at 11 to 14 weeks' gestation was classified as (1) normotensive (systolic blood pressure [SBP]
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Darwin, Kristin C. Federspiel, Jerome J. Schuh, Brittany L. Baschat, Ahmet A. Vaught, Arthur J. Tags: Original Article Source Type: research

Interleukin-6 as a Biomarker of Early-Onset Neonatal Sepsis
Am J Perinatol DOI: 10.1055/s-0040-1710010 Objective The aim of this study is to determine the utility of C reactive protein (CRP) and interleukin (IL)-6 in the diagnosis of neonatal sepsis (NS) in a neonatal intensive care unit (NICU) in the south of Colombia. Study Design A nonmatched case–control study was conducted. Convenience sampling was performed. Data were obtained from clinical records. IL-6 levels were determined using enzyme-linked immunosorbent assay. Receiver operator characteristic (ROC) curve analysis and Youden's index were used to determine the optimal cutoffs for CRP and IL-6 levels...
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Cort és, José S. Losada, Paula X. Fern ández, Laura X. Beltr án, Emilce DeLaura, Isabel Narv áez, Carlos F. Fonseca-Becerra, Carlos Eduardo Tags: Original Article Source Type: research

Use of the RAM Cannula with Early Bubble Continuous Positive Airway Pressure Requires Higher Pressures: Clinical and In vitro Evaluations
This study aimed to review early bCPAP pressures and bCPAP failure with the RAM cannula interface over a 6-year period. Study Design Retrospective, single-center study of infants delivered
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Claassen, Colleen C. Strand, Marya L. Williams, Howard L. Hillman, Noah H. Tags: Original Article Source Type: research

Early Gut Microbiota Changes in Preterm Infants with Bronchopulmonary Dysplasia: A Pilot Case –Control Study
Conclusion Infants with BPD are prone to develop gut dysbiosis in early life. A higher severity of illness and treatment intensity may indicate a higher risk of disrupting an anaerobic environment in the gut during the first month of life. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Chen, Shan-Ming Lin, Ching-Pin Jan, Ming-Shiou Tags: Original Article Source Type: research

Platelets and Immature Neutrophils in Preterm Infants with Feeding Intolerance
This study examined whether the combination of hematological indices and FI can be used as an early diagnostic tool for NEC or sepsis. Study Design This retrospective cohort study included infants born at
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Alhamad, Moath M.A. Kumar, Ambuj Chaaban, Hala Wickline, Karen M. Ho, Thao T.B. Tags: Original Article Source Type: research

Hemorrhage Risk Assessment on Admission: Utility for Prediction of Maternal Morbidity
Conclusion Women who were deemed high risk for hemorrhage using a hemorrhage risk assessment tool had five times higher risk for blood transfusion and EBL ≥ 1,000 mL compared with low-risk women. Given the low incidence of the outcomes explored, the hemorrhage risk assessment works moderately well to identify patients at risk for peripartum morbidity. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 23, 2020 Category: Perinatology & Neonatology Authors: Ahmadzia, Homa K. Phillips, Jaclyn M. Kleiman, Rose Gimovsky, Alexis C. Bathgate, Susan Luban, Naomi L.C. Amdur, Richard L. Tags: Original Article Source Type: research

N95 Filtering Facepiece Respirator Use during Pregnancy: A Systematic Review
Conclusion Limited duration N95 FFR use during pregnancy is unlikely to impart risk to the pregnant women or her fetus. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 21, 2020 Category: Perinatology & Neonatology Authors: Roeckner, Jared T. Krsti ć, Nevena Sipe, Bradley H. Obi čan, Sarah G. Tags: Original Article Source Type: research

A Framework for Coordination between Obstetric and Pediatric Providers in Public Health Emergencies: Lessons Learned from the Zika Outbreak in the United States, 2015 to 2017
We present a novel framework and strategies to improve care coordination and communication during an emergency response. The proposed framework includes (1) identification and collection of critical information to inform care, (2) key health care touchpoints for the maternal-infant dyad, and (3) primary pathways of communication and modes of transfer across touchpoints, as well as practical strategies. This framework and associated strategies can be modified to address the care coordination needs of pregnant women and their infants with possible exposure to other emerging infectious and noninfectious congenital threats tha...
Source: American Journal of Perinatology - May 21, 2020 Category: Perinatology & Neonatology Authors: Leeb, Rebecca T. Cree, Robyn A. Aird, Laura DeBiasi, Roberta L. Driggers, Rita W. Garbarczyk, Elizabeth Mofenson, Lynne M. Needle, Scott Rodriguez, Jeannie Curry, Christine Garc ía, Francisco Godfred-Cato, Shana Hawks, Debra Rosenblum, Elizabeth Dziuban, Tags: Original Article Source Type: research

COVID-19 in Pregnant Women: Case Series from One Large New York City Obstetrical Practice
Conclusions Among 92 women with confirmed or presumed COVID-19, the overall morbidity was low. These preliminary results are encouraging for pregnant women during the COVID-19 pandemic. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 21, 2020 Category: Perinatology & Neonatology Authors: Fox, Nathan S. Melka, Stephanie Tags: Original Article Source Type: research

Exclusion of Pregnant Women from Clinical Trials during the Coronavirus Disease 2019 Pandemic: A Review of International Registries
Conclusion Approximately 1.7% of current COVID-19 research is pregnancy related and the majority of trials either explicitly exclude or fail to address pregnancy. Only three interventional trials worldwide involved pregnant women. The knowledge gap concerning the safety and efficacy of interventions for COVID-19 created by the exclusion of pregnant women may ultimately harm them. While “ethical” concerns about fetal exposure are often cited, it is in fact unethical to habitually exclude pregnant women from research. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, US...
Source: American Journal of Perinatology - May 19, 2020 Category: Perinatology & Neonatology Authors: Smith, Devin D. Pippen, Jessica L. Adesomo, Adebayo A. Rood, Kara M. Landon, Mark B. Costantine, Maged M. Tags: Original Article Source Type: research

The Relationship between Status at Presentation and Outcomes among Pregnant Women with COVID-19
Conclusion Pregnant women who presented with COVID19-related symptoms and subsequently tested positive for COVID-19 have a higher rate of preterm delivery and need for respiratory support than asymptomatic pregnant women. It is important to be particularly rigorous in caring for COVID-19 infected pregnant women who present with symptoms. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 19, 2020 Category: Perinatology & Neonatology Authors: London, Viktoriya McLaren, Rodney Atallah, Fouad Cepeda, Catherine McCalla, Sandra Fisher, Nelli Stein, Janet L. Haberman, Shoshana Minkoff, Howard Tags: Original Article Source Type: research

Community Obstetrical Units Less Likely than Academic Units to Have Universal COVID-19 Testing
Am J Perinatol DOI: 10.1055/s-0040-1712454 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 19, 2020 Category: Perinatology & Neonatology Authors: Werner, Erika F. Louis, Judette M. Hughes, Brenna Han, Christina Shih-chi Norton, Mary E. Srinivas, Sindhu K. Tags: Letter to the Editor Source Type: research

Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review
Conclusion There is currently no direct evidence to support intrauterine vertical transmission of SARS-CoV-2. Additional RT-PCR tests on amniotic fluid, placenta, and cord blood are needed to ascertain the possibility of intrauterine vertical transmission. For pregnant women infected during their first and second trimesters, further studies focusing on long-term outcomes are needed. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 13, 2020 Category: Perinatology & Neonatology Authors: Yang, Ziyi Liu, Yi Tags: Short Communication Source Type: research

Laboratory Abnormalities in Pregnant Women with Novel Coronavirus Disease 2019
Am J Perinatol DOI: 10.1055/s-0040-1712181 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 12, 2020 Category: Perinatology & Neonatology Authors: Shi, Li Wang, Ying Yang, Haiyan Duan, Guangcai Wang, Yadong Tags: Short Communication Source Type: research

Telehealth for High-Risk Pregnancies in the Setting of the COVID-19 Pandemic
Am J Perinatol DOI: 10.1055/s-0040-1712121As New York City became an international epicenter of the novel coronavirus disease 2020 (COVID-19) pandemic, telehealth was rapidly integrated into prenatal care at Columbia University Irving Medical Center, an academic hospital system in Manhattan. Goals of implementation were to consolidate in-person prenatal screening, surveillance, and examinations into fewer in-person visits while maintaining patient access to ongoing antenatal care and subspecialty consultations via telehealth virtual visits. The rationale for this change was to minimize patient travel and thus risk for COVI...
Source: American Journal of Perinatology - May 12, 2020 Category: Perinatology & Neonatology Authors: Aziz, Aleha Zork, Noelia Aubey, Janice J. Baptiste, Caitlin D. D'Alton, Mary E. Emeruwa, Ukachi N. Fuchs, Karin M. Goffman, Dena Gyamfi-Bannerman, Cynthia Haythe, Jennifer H. LaSala, Anita P. Madden, Nigel Miller, Eliza C. Miller, Russell S. Monk, Catheri Tags: Original Article Source Type: research

A Proposed Plan for Prenatal Care to Minimize Risks of COVID-19 to Patients and Providers: Focus on Hypertensive Disorders of Pregnancy
Am J Perinatol DOI: 10.1055/s-0040-1710538Hypertensive disorders are the most common medical complications of pregnancy and a major cause of maternal and perinatal morbidity and death. The detection of elevated blood pressure during pregnancy is one of the cardinal aspects of optimal antenatal care. With the outbreak of novel coronavirus disease 2019 (COVID-19) and the risk for person-to-person spread of the virus, there is a desire to minimize unnecessary visits to health care facilities. Women should be classified as low risk or high risk for hypertensive disorders of pregnancy and adjustments can be accordingly made in ...
Source: American Journal of Perinatology - May 12, 2020 Category: Perinatology & Neonatology Authors: Barton, John R. Saade, George R. Sibai, Baha M. Tags: Clinical Opinion Source Type: research

Randomized Trials of Retosiban Versus Placebo or Atosiban in Spontaneous Preterm Labor
Conclusion Despite considerable efforts to conduct two adequate and well-controlled studies in patients with sPTL, both studies were unable to recruit effectively and consequently terminated prematurely. Key factors negatively affecting participation were patient and physician resistance to use of a placebo comparator, lack of investigator consensus on diagnostic criteria and acceptance of protocol procedures, and ethics committee decisions. Meaningful cooperation between pharmaceutical companies, regulatory authorities, and the obstetric community is essential for future development of drugs to treat sPTL. [...] Thie...
Source: American Journal of Perinatology - May 7, 2020 Category: Perinatology & Neonatology Authors: Saade, George Shennan, Andrew Beach, Kathleen J. Hadar, Eran Parilla, Barbara V. Snidow, Jerry Powell, Marcy Montague, Timothy H. Liu, Feng Komatsu, Yosuke McKain, Laura Thornton, Steven Tags: Original Article Source Type: research

COVID-19 in Newborns and Infants —Low Risk of Severe Disease: Silver Lining or Dark Cloud?
Am J Perinatol DOI: 10.1055/s-0040-1710512One hundred years after the 1918 influenza pandemic, we now face another pandemic with the severe acute respiratory syndrome–novel coronavirus-2 (SARS-CoV-2). There is considerable variability in the incidence of infection and severe disease following exposure to SARS-CoV-2. Data from China and the United States suggest a low prevalence of neonates, infants, and children, with those affected not suffering from severe disease. In this article, we speculate different theories why this novel agent is sparing neonates, infants, and young children. The low severity of SARS-CoV-2 i...
Source: American Journal of Perinatology - May 7, 2020 Category: Perinatology & Neonatology Authors: Rawat, Munmun Chandrasekharan, Praveen Hicar, Mark D. Lakshminrusimha, Satyan Tags: Clinical Opinion Source Type: research

Caring for Pregnant Patients with COVID-19: Practical Tips Getting from Policy to Practice
Am J Perinatol DOI: 10.1055/s-0040-1710539Novel coronavirus disease 2019 (COVID-19) is a pandemic with most American cases in New York. As an institution residing in a high-prevalence zip code, with over 8,000 births annually, we have cared for over 80 COVID-19-infected pregnant women, and have encountered many challenges in applying new national standards for care. In this article, we review how to change outpatient and inpatient practices, develop, and disseminate new hospital protocols, and we highlight the psychosocial challenges for pregnant patients and their providers. Key Points [...] Thieme Medical Publisher...
Source: American Journal of Perinatology - May 7, 2020 Category: Perinatology & Neonatology Authors: London, Viktoriya McLaren, Rodney Stein, Janet Atallah, Fouad Fisher, Nelli Haberman, Shoshana McCalla, Sandra Minkoff, Howard Tags: Clinical Opinion Source Type: research

Does Duration Off Respiratory Support Prior to Discharge from NICU Predict Hospital Readmission among Extremely Low Gestational Age Neonates?
Am J Perinatol DOI: 10.1055/s-0040-1710011 Objective Our objective was to determine if the duration off respiratory support prior to discharge home from the neonatal intensive care unit (NICU) would impact hospital readmission rates among extremely low gestational age neonates (ELGAN). Study Design In this retrospective chart review, we examined readmission rates for ELGAN admitted to the Montefiore–Weiler NICU between 2013 and 2015. Results Of 140 infants born at
Source: American Journal of Perinatology - May 5, 2020 Category: Perinatology & Neonatology Authors: Pattnaik, Priyam Palmaccio, Samantha Aschner, Judy Eisenberg, Ruth Choi, Jaeun LaTuga, M. Susan Tags: Original Article Source Type: research

Hospital Safety-Net Burden and Risk for Readmissions and Severe Maternal Morbidity
Conclusion This study found that high safety-net burden hospitals may be a higher risk setting for obstetric care. Improvement of outcomes in high-burden settings may be important in overall efforts to reduce maternal risk. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 5, 2020 Category: Perinatology & Neonatology Authors: McKinley, Lilian P. Wen, Timothy Gyamfi-Bannerman, Cynthia Wright, Jason D. Goffman, Dena Sheen, Jean-Ju D'Alton, Mary E. Friedman, Alexander M. Tags: Original Article Source Type: research

Maternal Health after Stillbirth: Postpartum Hospital Readmission in California
Conclusion Based on our findings, women who have stillbirths are at higher risk of postpartum readmissions within 6 weeks of giving birth than women who have live births. Women who have stillbirths may benefit from additional monitoring and counseling after hospital discharge for potential postpartum medical and psychiatric complications. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 4, 2020 Category: Perinatology & Neonatology Authors: Wall-Wieler, Elizabeth Butwick, Alexander J. Gibbs, Ronald S. Lyell, Deirdre J. Girsen, Anna I. El-Sayed, Yasser Y. Carmichael, Suzan L. Tags: Original Article Source Type: research

Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2
Conclusion Our findings highlight the importance of follow-up of newborns to mothers with COVID-19 in pregnancy, since they remain at risk of contracting the infection in the early period of life and long-term consequences are still unknown. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 2, 2020 Category: Perinatology & Neonatology Authors: Buonsenso, Danilo Costa, Simonetta Sanguinetti, Maurizio Cattani, Paola Posteraro, Brunella Marchetti, Simona Carducci, Brigida Lanzone, Antonio Tamburrini, Enrica Vento, Giovanni Valentini, Piero Tags: Short Communication Source Type: research

COVID-19 and Neonatal Respiratory Care: Current Evidence and Practical Approach
Am J Perinatol DOI: 10.1055/s-0040-1710522The novel coronavirus disease 2019 (COVID-19) pandemic has urged the development and implementation of guidelines and protocols on diagnosis, management, infection control strategies, and discharge planning. However, very little is currently known about neonatal COVID-19 and severe acute respiratory syndrome–coronavirus-2 (SARS-CoV-2) infections. Thus, many questions arise with regard to respiratory care after birth, necessary protection to health care workers (HCW) in the delivery room and neonatal intensive care unit (NICU), and safety of bag and mask ventilation, noninvasi...
Source: American Journal of Perinatology - May 2, 2020 Category: Perinatology & Neonatology Authors: Shalish, Wissam Lakshminrusimha, Satyanarayana Manzoni, Paolo Keszler, Martin Sant'Anna, Guilherme M. Tags: Review Article Source Type: research

Resveratrol Relieves Hyperoxia-Induced Brain Injury in Neonatal Rats by Activating Sirt1
Conclusion Resveratrol alleviated brain apoptosis induced by hyperoxia in neonatal rats by upregulating Sirt1-mediated pathways, suggesting its potentially beneficial role in the treatment of brain injury induced by hyperoxia. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - May 1, 2020 Category: Perinatology & Neonatology Authors: Kang, Lan Dong, Wenbin Li, Xiaobin Ruan, Ying Zhang, Rong Tags: Original Article Source Type: research

Predictors of Early Preterm Birth Despite Vaginal Progesterone Therapy in Singletons with Short Cervix
Am J Perinatol DOI: 10.1055/s-0040-1710008 Objective Identify the incidence of and risk factors for early preterm birth (PTB) (delivery
Source: American Journal of Perinatology - April 28, 2020 Category: Perinatology & Neonatology Authors: Boelig, Rupsa C. Naert, Mackenzie N. Fox, Nathan S. Hennessy, Sean Chervoneva, Inna Berghella, Vincenzo Roman, Amanda Tags: SMFM Fellowship Series Article Source Type: research

Structured Neonatal Point-of-Care Ultrasound Training Program
Conclusion Future efforts need to be dedicated to the ongoing development of neonatal POC US as a clinical instrument. It should allow for eventual paradigm change and improved effectiveness in management of critically ill neonates. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 28, 2020 Category: Perinatology & Neonatology Authors: Kurepa, Dalibor Boyar, Vitalya Zaghloul, Nahla Beachy, Joanna Zaytseva, Alla Teng, David Cooper, Rubin Klewer, Scott Amodio, John Tags: Original Article Source Type: research

General Guidelines in the Management of an Obstetrical Patient on the Labor and Delivery Unit during the COVID-19 Pandemic
Am J Perinatol DOI: 10.1055/s-0040-1710308Novel coronavirus disease 2019 (COVID-19) is a respiratory tract infection that was first identified in China. Since its emergence in December 2019, the virus has rapidly spread, transcending geographic barriers. The World Health Organization and the Centers for Disease Control and Prevention have declared COVID-19 as a public health crisis. Data regarding COVID-19 in pregnancy is limited, consisting of case reports and small cohort studies. However, obstetric patients are not immune from the current COVID-19 pandemic, and obstetric care will inevitably be impacted by the current e...
Source: American Journal of Perinatology - April 28, 2020 Category: Perinatology & Neonatology Authors: Stephens, Angela J. Barton, John R. Bentum, Nana-Ama Ankumah Blackwell, Sean C. Sibai, Baha M. Tags: Clinical Opinion Source Type: research

Adverse Outcomes among Low-Risk Pregnancies at 39 to 41 Weeks: Stratified by Birth Weight Percentile
Conclusion Among low-risk pregnancies, the risks of composite neonatal and maternal adverse outcomes increase from 39 through 41 weeks' gestation, irrespective of whether newborns are SGA, LGA, or AGA. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 27, 2020 Category: Perinatology & Neonatology Authors: Mendez-Figueroa, Hector Chen, Han Yang Chauhan, Suneet P. Tags: Original Article Source Type: research

Consistency between Impedance Technique and Echocardiogram Hemodynamic Measurements in Neonates
Conclusion Agreement between the IT and ECHO in the cardiac output measurement appeared acceptable. However, the accuracy and precision of the IT approach should be further investigated using a larger sample. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 25, 2020 Category: Perinatology & Neonatology Authors: Wu, Wenshen Lin, Sulian Xie, Caixuan Li, Jianbo Lie, Jingen Qiu, Shuyi Tags: Original Article Source Type: research

Successful Treatment of Preterm Labor in Association with Acute COVID-19 Infection
Am J Perinatol DOI: 10.1055/s-0040-1709993Novel coronavirus disease 2019 (COVID-19) infection occurring during pregnancy is associated with an increased risk of preterm delivery. This case report describes successful treatment of preterm labor during acute COVID-19 infection. Standard treatment for preterm labor may allow patients with acute COVID-19 infection to recover without the need for preterm delivery. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: A...
Source: American Journal of Perinatology - April 24, 2020 Category: Perinatology & Neonatology Authors: Browne, Paul C. Linfert, Jennifer B. Perez-Jorge, Emilio Tags: Short Communication Source Type: research

Specialized Pediatric Palliative Care in Neonates with Life-Limiting Illness: A Systematic Review
Conclusion Specialized versus may have an impact on neonates with life-limiting conditions and their families. More studies that evaluate the impact of specialized versus in neonates with sound statistical analysis is warranted. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 24, 2020 Category: Perinatology & Neonatology Authors: Zuniga-Villanueva, Gregorio Widger, Kimberley Medeiros, Christina Trenholm, Madeline Streuli, J ürg C. Tags: Original Article Source Type: research

The Maternal Impact, Health Burden, and Postpartum Sequela in Triplet Pregnancies: A Retrospective Cohort
Conclusion Nulliparity and presence of pregnancy complications are pertinent to triplet outcomes. This study provides valuable information for anticipatory guidance and preconception counseling to patients considering artificial reproductive technology. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 24, 2020 Category: Perinatology & Neonatology Authors: Lambers, Donna S. Allen, Jennifer Gottula, Jessica Devaiah, C. Ganga Habli, Mounira Tags: Original Article Source Type: research

Vitamin D Status May Help Explain Maternal Race and Ethnic Factors in Primary Cesarean Section Delivery
Am J Perinatol DOI: 10.1055/s-0040-1709494 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 24, 2020 Category: Perinatology & Neonatology Authors: Grant, William B. Tags: Letter to the Editor Source Type: research

Near-Infrared Spectroscopy: A Tool for Diagnosing Necrotizing Enterocolitis at Onset of Symptoms in Preterm Neonates with Acute Gastrointestinal Symptoms
Conclusion In this study, NIRS monitoring was unable to individualize NEC in premature infants with acute gastrointestinal symptoms. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 23, 2020 Category: Perinatology & Neonatology Authors: Le Bouhellec, Julia Prodhomme, Olivier Mura, Thibault Jacquot, Aur élien Combes, Cl émentine Gamon, Lucie Durand, Sabine Filleron, Anne Cambonie, Gilles Tags: Original Article Source Type: research

Hepatitis C Virus in Pregnancy: A Systematic Review of the Literature
Conclusion There is evidence that risk-based screening fails to identify a large proportion of HCV positive women in pregnancy and that pregnant women with HCV risk factors and consistent with current screening guidelines fail to be tested. We urge for the adoption of universal screening to identify these women and offer treatment. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 22, 2020 Category: Perinatology & Neonatology Authors: Andes, Alexandra Ellenberg, Kerry Vakos, Amanda Collins, James Fryer, Kimberly Tags: Review Article Source Type: research

Mild Neonatal Acidemia is Associated with Neonatal Morbidity at Term
Conclusion These data demonstrate that term neonates with mild acidemia at birth are at higher odds for short-term morbidity compared with neonates with normal UA pH. Furthermore, among neonates with mild acidemia, those with lower UA pH had worse neonatal outcomes than those with higher UA pH. This suggests that closer evaluation of neonates with UA pH higher than traditionally used could allow for earlier detection of morbidity and possible intervention. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract &nb...
Source: American Journal of Perinatology - April 22, 2020 Category: Perinatology & Neonatology Authors: Bailey, Erin J. Frolova, Antonina I. L ópez, Julia D. Raghuraman, Nandini Macones, George A. Cahill, Alison G. Tags: Original Article Source Type: research

Severe COVID-19 during Pregnancy and Possible Vertical Transmission
We report a severe presentation of COVID-19 during pregnancy. To our knowledge, this is the earliest reported positive PCR in the neonate, raising the concern for vertical transmission. We suggest pregnant women should be considered as a high-risk group and minimize exposures for these reasons. Key Points [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - April 18, 2020 Category: Perinatology & Neonatology Authors: Alzamora, Maria Claudia Paredes, Tania Caceres, David Webb, Camille M. Valdez, Luis M. La Rosa, Mauricio Tags: Short Communication Source Type: research

Considerations for Obstetric Care during the COVID-19 Pandemic
Am J Perinatol DOI: 10.1055/s-0040-1710051The novel coronavirus disease 2019 (COVID-19) is a growing pandemic that is impacting daily life across the globe. Though disease is often mild, in high-risk populations, severe disease often leads to intubation, intensive care admission (ICU) admission, and in many cases death. The implications for pregnancy remain largely unknown. Early data suggest that COVID-19 may not pose increased risk in the pregnant population. Vertical transmission has not been confirmed. Because no treatment, no vaccine and no herd immunity exist, social distancing is the best mechanism available to prot...
Source: American Journal of Perinatology - April 17, 2020 Category: Perinatology & Neonatology Authors: Dotters-Katz, Sarah K. Hughes, Brenna L. Tags: Review Article Source Type: research