Improved Cervical Cord Lesion Detection with 3D-MP2RAGE Sequence in Patients with Multiple Sclerosis [SPINE]
In this study, we compared the 3D-MP2RAGE sequence with the conventional Magnetic Resonance Imaging in Multiple Sclerosis (MAGNIMS) set for cervical cord lesion detection in 28 patients with multiple sclerosis. 3D-MP2RAGE allowed better detection of cervical lesions (+62%) in this population, with better confidence, due to optimized contrast and high spatial resolution. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Demortiere, S., Lehmann, P., Pelletier, J., Audoin, B., Callot, V. Tags: SPINE Source Type: research

High Prevalence of Spinal Cord Cavernous Malformations in the Familial Cerebral Cavernous Malformations Type 1 Cohort [SPINE]
CONCLUSIONS: Spinal cord cavernous malformations occur commonly in the familial cerebral cavernous malformation population. Gradient-based sequences are the most sensitive and should be used when spinal cord cavernous malformations are suspected. This study establishes the prevalence in the familial population at around 70% and supports the idea that this condition is a progressive systemic disease that affects the entire central nervous system. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Mabray, M. C., Starcevich, J., Hallstrom, J., Robinson, M., Bartlett, M., Nelson, J., Zafar, A., Kim, H., Morrison, L., Hart, B. L. Tags: SPINE Source Type: research

Major Radiologic and Clinical Outcomes of Total Spine MRI Performed in the Emergency Department at a Major Academic Medical Center [SPINE]
BACKGROUND AND PURPOSE: Total spine MRIs are requested by the emergency department when focused imaging can not be ordered on the basis of history or clinical findings. However, their efficacy is not known. We assessed the following: 1) major radiologic and clinical outcomes of total spine MR imaging performed by the emergency department, and 2) whether the presence of a high-risk clinical profile and/or neurologic findings impacts the clinical outcomes. MATERIALS AND METHODS: Total spine MRIs requested by the emergency department during a 28-month period were evaluated for major radiologic (cord compression, cauda equina...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Huang, C. W. C., Ali, A., Chang, Y.- M., Bezuidenhout, A. F., Hackney, D. B., Edlow, J. A., Bhadelia, R. A. Tags: SPINE Source Type: research

Counterpoint: Conventional Fluoroscopy-Guided Selective Cervical Nerve Root Block--A Safe, Effective, and Efficient Modality in the Hands of an Experienced Proceduralist [SPINE]
CONCLUSIONS: Conventional fluoroscopy-guided selective cervical nerve root block is an efficacious, efficient, and safe outpatient procedure when performed by a skilled and experienced proceduralist. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Ott, F. W., Pluhm, R., Ozturk, K., McKinney, A. M., Rykken, J. B. Tags: SPINE Source Type: research

Fetal and Neonatal MRI Predictors of Aggressive Early Clinical Course in Vein of Galen Malformation [PEDIATRICS]
BACKGROUND AND PURPOSE: Neonates with vein of Galen malformations are split into 2 cohorts: one needing urgent neonatal embolization, with relatively high mortality and morbidity even with expert care, and a cohort in which embolization can be deferred until infancy, with far better prognosis. We aimed to identify brain MR imaging characteristics obtained from fetal and early neonatal scans that can predict the clinical presentation. MATERIALS AND METHODS: Patients with vein of Galen malformations were stratified into a neonatal at-risk cohort if the patient needed urgent neonatal intervention or if neonatal death occurre...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Arko, L., Lambrych, M., Montaser, A., Zurakowski, D., Orbach, D. B. Tags: PEDIATRICS Source Type: research

Effect of Age on GABA+ and Glutathione in a Pediatric Sample [PEDIATRICS]
CONCLUSIONS: We demonstrate increases in GABA and no differences in glutathione with age in a healthy pediatric sample. This study provides insight into neuronal maturation in children and may facilitate better understanding of normative behavioral development and the pathophysiology of developmental disorders. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Saleh, M. G., Papantoni, A., Mikkelsen, M., Hui, S. C. N., Oeltzschner, G., Puts, N. A., Edden, R. A. E., Carnell, S. Tags: PEDIATRICS Source Type: research

New MRI Findings in Fukuyama Congenital Muscular Dystrophy: Brain Stem and Venous System Anomalies [PEDIATRICS]
CONCLUSIONS: Superficial brain stem structural and signal abnormalities would be useful MR imaging findings to diagnose Fukuyama congenital muscular dystrophy as well as venous system abnormalities. Clinicians must keep in mind that this disease has a high risk of hemorrhage. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Hirasawa-Inoue, A., Sato, N., Shigemoto, Y., Kimura, Y., Ishiyama, A., Takeshita, E., Mori-Yoshimura, M., Oya, Y., Takahashi, Y., Komaki, H., Matsuda, H., Sasaki, M. Tags: PEDIATRICS Source Type: research

A Case Series of X-Linked Deafness-2 with Sensorineural Hearing Loss, Stapes Fixation, and Perilymphatic Gusher: MR Imaging and Clinical Features of Hypothalamic Malformations [HEAD & NECK]
SUMMARY: X-linked deafness-2 (DFNX2) is an X-linked recessive disorder characterized by profound sensorineural hearing loss and a pathognomonic temporal bone deformity. Because hypothalamic malformations associated with DFNX2 have been rarely described, we aimed to further describe these lesions and compare them with features of a nonaffected population. All patients diagnosed with DFNX2 between 2006 and 2019 were included and compared with age-matched patients with normal MR imaging findings and without hypothalamic dysfunction. MR imaging features differing between groups were selected to help identify DFNX2. Sensitivity...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Prat Matifoll, J.- A., Wilson, M., Goetti, R., Birman, C., Bennett, B., Peadon, E., Prats-Uribe, A., Prelog, K. Tags: HEAD & amp; NECK Source Type: research

Accuracy of MR Imaging for Detection of Sensorineural Hearing Loss in Infants with Bacterial Meningitis [HEAD & NECK]
BACKGROUND AND PURPOSE: Bacterial meningitis most commonly affects young children and can result in critical adverse outcomes, including sensorineural hearing loss (SNHL). The purpose of this study is to determine the diagnostic accuracy of MR imaging for predicting the development of SNHL among infants with bacterial meningitis. MATERIALS AND METHODS: A retrospective review was performed among infants (age
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Orman, G., Kukreja, M. K., Vallejo, J. G., Desai, N., Huisman, T. A. G. M., Kralik, S. F. Tags: HEAD & amp; NECK Source Type: research

New Imaging Findings of Incomplete Partition Type III Inner Ear Malformation and Literature Review [HEAD & NECK]
SUMMARY: Incomplete partition type III, also referred to as X-linked deafness, is a rare genetic inner ear malformation. Its characteristic CT findings, including bulbous dilation of the internal auditory canal and absence of the modiolus with the interscalar septa present, have been well-recognized. In this series of 19 cases, we report the abnormalities of the vestibule and semicircular canals and provide a comprehensive description of their CT and MR imaging findings. The inner ear malformations in incomplete partition type III were bilateral and basically symmetric, with involvement of the internal auditory canal, nerv...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Hong, R., Du, Q., Pan, Y. Tags: HEAD & amp; NECK Source Type: research

Positive Predictive Value of Neck Imaging Reporting and Data System Categories 3 and 4 Posttreatment FDG-PET/CT in Head and Neck Squamous Cell Carcinoma [HEAD & NECK]
CONCLUSIONS: The positive predictive value of Neck Imaging Reporting and Data System 3 on posttreatment PET/CT is relatively low. Thus, Neck Imaging Reporting and Data System 3 findings should be confirmed with tissue sampling before instituting new salvage treatment regimens to avoid unnecessary overtreatment and its associated toxicities. Neck Imaging Reporting and Data System 4 reliably indicates recurrent disease. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Wangaryattawanich, P., Branstetter, B. F., Ly, J. D., Duvvuri, U., Heron, D. E., Rath, T. J. Tags: HEAD & amp; NECK Source Type: research

Fully Automated Segmentation of Globes for Volume Quantification in CT Images of Orbits using Deep Learning [FUNCTIONAL]
CONCLUSIONS: We showed that with fast prediction times, we can reliably detect and quantify globe volumes in CT images of the orbits across a variety of acquisition parameters. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Umapathy, L., Winegar, B., MacKinnon, L., Hill, M., Altbach, M. I., Miller, J. M., Bilgin, A. Tags: FUNCTIONAL Source Type: research

Relevance of Distal Arterial Collapse in Stenting of Atherosclerotic Near-Occlusion of the Carotid Artery [INTERVENTIONAL]
CONCLUSIONS: Care should be taken to minimize hyperperfusion risk in patients with near-occlusion undergoing CAS, especially in the subgroup of patients with collapse and in patients with both symptomatic and asymptomatic carotid stenosis. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Cay, F., Cil, B. E., Balcı, S., Arsava, E. M., Topcuoglu, M. A., Arat, A. Tags: INTERVENTIONAL Source Type: research

Fast Stent Retrieval Improves Recanalization Rates of Thrombectomy: Experimental Study on Different Thrombi [INTERVENTIONAL]
CONCLUSIONS: In our experimental model, a fast removal improved recanalization rates of mechanical thrombectomy, especially in the case of fibrin-rich clots. An in vivo confirmation is warranted to see whether our findings can have an impact in clinical practice. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Soize, S., Pierot, L., Mirza, M., Gunning, G., Gilvarry, M., Gawlitza, M., Vivien, D., Zuber, M., Touze, E. Tags: INTERVENTIONAL Source Type: research

Long-Term Rupture Risk in Patients with Unruptured Intracranial Aneurysms Treated with Endovascular Therapy: A Systematic Review and Meta-Analysis [INTERVENTIONAL]
CONCLUSIONS: Given a 5% retreatment rate, postcoil embolization spontaneous rupture of previously unruptured, small- and medium-sized, well-treated aneurysms is exceedingly rare. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Rizvi, A., Seyedsaadat, S. M., Alzuabi, M., Murad, M. H., Kadirvel, R., Brinjikji, W., Kallmes, D. F. Tags: INTERVENTIONAL Source Type: research

Multicenter Postmarket Analysis of the Neuroform Atlas Stent for Stent-Assisted Coil Embolization of Intracranial Aneurysms [INTERVENTIONAL]
We present a postmarket multicenter analysis of the Neuroform Atlas stent. MATERIALS AND METHODS: On the basis of retrospective chart review from 11 academic centers, we analyzed patients treated with the Neuroform Atlas after FDA exemption from January 2018 to June 2019. Clinical and radiologic parameters included patient demographics, aneurysm characteristics, stent parameters, complications, and outcomes at discharge and last follow-up. RESULTS: Overall, 128 aneurysms in 128 patients (median age, 62 years) were treated with 138 stents. Risk factors included smoking (59.4%), multiple aneurysms (27.3%), and family histo...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Burkhardt, J.- K., Srinivasan, V., Srivatsan, A., Albuquerque, F., Ducruet, A. F., Hendricks, B., Gross, B. A., Jankowitz, B. T., Thomas, A. J., Ogilvy, C. S., Maragkos, G. A., Enriquez-Marulanda, A., Crowley, R. W., Levitt, M. R., Kim, L. J., Griessenaue Tags: INTERVENTIONAL Source Type: research

Long-Term Outcomes of the WEB Device for Treatment of Wide-Neck Bifurcation Aneurysms [INTERVENTIONAL]
BACKGROUND AND PURPOSE: Treatment of wide-neck bifurcation aneurysms using endovascular therapy is still challenging even with the development of treatment devices. The purpose of this investigation was to assess the safety and efficacy of treatment with a Woven EndoBridge (WEB) device for wide-neck bifurcation aneurysms. MATERIALS AND METHODS: All patients treated with a WEB device at our institution between May 2009 and November 2016 were retrospectively evaluated. Clinical and imaging evaluation, aneurysm occlusion status, and modified Rankin scale score were analyzed 1 day after treatment and in the short- (
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Fujimoto, M., Lylyk, I., Bleise, C., Albina, P., Chudyk, J., Lylyk, P. Tags: INTERVENTIONAL Source Type: research

Resting-State Brain Activity for Early Prediction Outcome in Postanoxic Patients in a Coma with Indeterminate Clinical Prognosis [FUNCTIONAL]
BACKGROUND AND PURPOSE: Early outcome prediction of postanoxic patients in a coma after cardiac arrest proves challenging. Current prognostication relies on multimodal testing, using clinical examination, electrophysiologic testing, biomarkers, and structural MR imaging. While this multimodal prognostication is accurate for predicting poor outcome (ie, death), it is not sensitive enough to identify good outcome (ie, consciousness recovery), thus leaving many patients with indeterminate prognosis. We specifically assessed whether resting-state fMRI provides prognostic information, notably in postanoxic patients in a coma wi...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Pugin, D., Hofmeister, J., Gasche, Y., Vulliemoz, S., Lövblad, K.- O., Ville, D. V. D., Haller, S. Tags: FUNCTIONAL Source Type: research

Prediction of Outcome Using Quantified Blood Volume in Aneurysmal SAH [FUNCTIONAL]
BACKGROUND AND PURPOSE: In patients with SAH, the amount of blood is strongly associated with clinical outcome. However, it is commonly estimated with a coarse grading scale, potentially limiting its predictive value. Therefore, we aimed to develop and externally validate prediction models for clinical outcome, including quantified blood volumes, as candidate predictors. MATERIALS AND METHODS: Clinical and radiologic candidate predictors were included in a logistic regression model. Unfavorable outcome was defined as a modified Rankin Scale score of 4–6. An automatic hemorrhage-quantification algorithm calculated th...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: van der Steen, W. E., Marquering, H. A., Ramos, L. A., van den Berg, R., Coert, B. A., Boers, A. M. M., Vergouwen, M. D. I., Rinkel, G. J. E., Velthuis, B. K., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Vandertop, W. P., Verbaan, D. Tags: FUNCTIONAL Source Type: research

Morphometric MRI Analysis: Improved Detection of Focal Cortical Dysplasia Using the MP2RAGE Sequence [FUNCTIONAL]
CONCLUSIONS: In this study, MP2RAGE-based morphometric analysis created clearer output maps with larger lesion volumes and higher z scores than the MPRAGE-based analysis. This new approach may improve the detection of subtle, otherwise overlooked focal cortical dysplasia. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Demerath, T., Rubensdörfer, L., Schwarzwald, R., Schulze-Bonhage, A., Altenmüller, D.- M., Kaller, C., Kober, T., Huppertz, H.- J., Urbach, H. Tags: FUNCTIONAL Source Type: research

Value of 3T Susceptibility-Weighted Imaging in the Diagnosis of Multiple Sclerosis [ADULT BRAIN]
CONCLUSIONS: A single 3T SWI scan offers valuable diagnostic information, which has the potential to prevent MS misdiagnosis. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Clarke, M. A., Pareto, D., Pessini-Ferreira, L., Arrambide, G., Alberich, M., Crescenzo, F., Cappelle, S., Tintore, M., Sastre-Garriga, J., Auger, C., Montalban, X., Evangelou, N., Rovira, A. Tags: ADULT BRAIN Source Type: research

Brain Network Disruption in Whiplash [FUNCTIONAL]
In this study, a sample of participants with chronic whiplash injuries were scanned by using resting-state fMRI to assess brain network changes associated with long-term outcome metrics. MATERIALS AND METHODS: Resting-state fMRI was collected for 23 participants and used to calculate network modularity, a quantitative measure of the functional segregation of brain region communities. This was analyzed for associations with whiplash-associated disorder outcome metrics, including scales of neck disability, traumatic distress, depression, and pain. In addition to these clinical scales, cervical muscle fat infiltration was qu...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Higgins, J. P., Elliott, J. M., Parrish, T. B. Tags: FUNCTIONAL Source Type: research

Voxel-Based Morphometry--from Hype to Hope. A Study on Hippocampal Atrophy in Mesial Temporal Lobe Epilepsy [FUNCTIONAL]
BACKGROUND AND PURPOSE: Automated volumetry of the hippocampus is considered useful to assist the diagnosis of hippocampal sclerosis in temporal lobe epilepsy. However, voxel-based morphometry is rarely used for individual subjects because of high rates of false-positives. We investigated whether an approach with high dimensional warping to the template and nonparametric statistics would be useful to detect hippocampal atrophy in patients with hippocampal sclerosis. MATERIALS AND METHODS: We performed single-subject voxel-based morphometry with nonparametric statistics within the framework of Statistical Parametric Mappin...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Riederer, F., Seiger, R., Lanzenberger, R., Pataraia, E., Kasprian, G., Michels, L., Beiersdorf, J., Kollias, S., Czech, T., Hainfellner, J., Baumgartner, C. Tags: FUNCTIONAL Source Type: research

Application of Deep Learning to Predict Standardized Uptake Value Ratio and Amyloid Status on 18F-Florbetapir PET Using ADNI Data [FUNCTIONAL]
CONCLUSIONS: Deep learning algorithms can estimate standardized uptake value ratio and use this to classify 18F-florbetapir PET scans. Such methods have promise to automate this laborious calculation, enabling quantitative measurements rapidly and in settings without extensive image processing manpower and expertise. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Reith, F., Koran, M. E., Davidzon, G., Zaharchuk, G., for the Alzheimer's Disease Neuroimaging Initiative Tags: FUNCTIONAL Source Type: research

4D Flat Panel Conebeam CTA for In Vivo Imaging of the Microvasculature of the Human Cortex with a Novel Software Prototype [ADULT BRAIN]
SUMMARY: It was the aim of our pilot study to investigate whether time-resolved flat panel conebeam CTA is able to demonstrate small cortical vessels in vivo. In 8 patients with small AVMs, time-resolved coronal MPRs of the vasculature of the frontal cortex were recalculated from 3D rotational angiography datasets with the use of a novel software prototype. 4D flat panel conebeam CTA demonstrated the course of the cortical arteries with small perpendicular side branches to the underlying cortex. Pial arterial and venous networks could also be identified, corresponding to findings in injection specimens. Reasonable image qu...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Huizinga, N., Keil, F., Birkhold, A., Kowarschik, M., Tritt, S., Berkefeld, J. Tags: ADULT BRAIN Source Type: research

Comparison of MRI, MRA, and DSA for Detection of Cerebral Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia [ADULT BRAIN]
CONCLUSIONS: This study reinforces the use of MR imaging as a primary screening tool for cerebral AVMs in patients with hereditary hemorrhagic telangiectasia and suggests that 3D-T1 postgadolinium and 2D-T1 postgadolinium performed at 3T are the highest yield sequences. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Vella, M., Alexander, M. D., Mabray, M. C., Cooke, D. L., Amans, M. R., Glastonbury, C. M., Kim, H., Wilson, M. W., Langston, D. E., Conrad, M. B., Hetts, S. W. Tags: ADULT BRAIN Source Type: research

Asymptomatic COVID-19: What the Neuroradiologist Needs to Know about Pulmonary Manifestations [research-article]
We report the case of an asymptomatic patient undergoing a spine CT examination for trauma who was incidentally found to have lung abnormalities later confirmed to be COVID-19. We aim to familiarize neuroradiologists with the spectrum of COVID-19 pulmonary manifestations that are likely to be observed on neck and spine CT imaging. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Barajas, R. F., Rufener, G., Starkey, J., Duncan, T., Fuss, C. Tags: research-article Source Type: research

From the Eye of the Storm: Multi-Institutional Practical Perspectives on Neuroradiology from the COVID-19 Outbreak in New York City [research-article]
This article highlights adaptive strategies that were undertaken at the epicenter of the outbreak in New York City during the past 4–6 weeks, as experienced by 5 large neuroradiology academic departments. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Phillips, C. D., Shatzkes, D. R., Moonis, G., Hsu, K. A., Doshi, A., Filippi, C. G. Tags: research-article Source Type: research

Preoperative Evaluation of Craniopagus Twins: Anatomy, Imaging Techniques, and Surgical Management [PEDIATRICS]
SUMMARY: Craniopagus twins are a rare congenital malformation in which twins are conjoined at the head. Although there is high prenatal and postnatal mortality for craniopagus twins, successful separation has become more common due to advances in neuroimaging, neuroanesthesia, and neurosurgical techniques. Joined brain tissue, shared arteries and veins, and defects in the skull and dura make surgery technically challenging, and neuroimaging plays an important role in preoperative planning. Drawing on our experience from consultation for multiple successful separations of craniopagus twins, we discuss what radiologists need...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Goldman-Yassen, A. E., Goodrich, J. T., Miller, T. S., Farinhas, J. M. Tags: PEDIATRICS Source Type: research

MR-Eye: High-Resolution Microscopy Coil MRI for the Assessment of the Orbit and Periorbital Structures, Part 1: Technique and Anatomy [HEAD & NECK]
SUMMARY: Microscopy coil MR imaging of the orbits has been described previously as a technique for anatomic depiction. In the first part of this 2-part series, the improvement in spatial resolution that the technique offers compared with conventional MR imaging of the orbits is demonstrated. We provide a guide to implementing the technique, sharing pearls and pitfalls gleaned from our own practice to make implementation of microscopy coil MR imaging at your own center easy. As a quick reference guide to the small-scale structures encountered when reading the studies, a short anatomy section is included, which doubles as a ...
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Dobbs, N. W., Budak, M. J., White, R. D., Zealley, I. A. Tags: HEAD & amp; NECK Source Type: research

Gadolinium Deposition Safety: Seeking the Patients Perspective [editorial]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Mallio, C. A., Quattrocchi, C. C., Rovira, A., Parizel, P. M. Tags: editorial Source Type: research

Perspectives [other]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Vargas, M. I. Tags: other Source Type: research

Reply: [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Foesleitner, O., Nenning, K.- H., Bartha-Doering, L., Baumgartner, C., Pataraia, E., Moser, D., Schwarz, M., Schmidbauer, V., Hainfellner, J. A., Czech, T., Dorfer, C., Langs, G., Prayer, D., Bonelli, S., Kasprian, G. Tags: LETTERS Source Type: research

The Ubiquitous Use of Resting State as a Control Task for Language Mapping in Task-Based Functional MRI [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Middlebrooks, E. H., Sabsevitz, D. S. Tags: LETTERS Source Type: research

Myelin Imaging Can Be Affected by a Number of Factors [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Hagiwara, A., Hori, M., Andica, C., Abe, O., Aoki, S. Tags: LETTERS Source Type: research

Reply: [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Bonasia, S., Robert, T. Tags: LETTERS Source Type: research

The Significance of Natural Anastomoses among Intracranial Vessels in Moyamoya Disease [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Yu, J., Zhang, J., Chen, J. Tags: LETTERS Source Type: research

"No Man is an Island" John Donne [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Lim, C. C. T., Tsuchiya, K. Tags: LETTERS Source Type: research

Neuroradiologists, Be Mindful of the Neuroinvasive Potential of COVID-19 [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Morris, M., Zohrabian, V. M. Tags: LETTERS Source Type: research

Stroke Health Care Use and COVID-19 [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Derraz, I. Tags: LETTERS Source Type: research

How the Lives of Neuroradiologists and Neurosurgeons Have Been Changed by COVID-19 [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 10, 2020 Category: Radiology Authors: Vargas, M. I., Meling, T. R. Tags: LETTERS Source Type: research

Celebrating 35 Years of the AJNR: May 1985 edition [35 YEARS AGO IN AJNR]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Tags: 35 YEARS AGO IN AJNR Source Type: research

MR Myelography for the Detection of CSF-Venous Fistulas [SPINE]
We report 3 cases in which the CSF-venous fistula was occult on CT myelography but readily detected using MR myelography. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Authors: Chazen, J. L., Robbins, M. S., Strauss, S. B., Schweitzer, A. D., Greenfield, J. P. Tags: SPINE Source Type: research

Sensitivity of the Inhomogeneous Magnetization Transfer Imaging Technique to Spinal Cord Damage in Multiple Sclerosis [FUNCTIONAL]
BACKGROUND AND PURPOSE: The inhomogeneous magnetization transfer technique has demonstrated high specificity for myelin, and has shown sensitivity to multiple sclerosis-related impairment in brain tissue. Our aim was to investigate its sensitivity to spinal cord impairment in MS relative to more established MR imaging techniques (volumetry, magnetization transfer, DTI). MATERIALS AND METHODS: Anatomic images covering the cervical spinal cord from the C1 to C6 levels and DTI, magnetization transfer/inhomogeneous magnetization transfer images at the C2/C5 levels were acquired in 19 patients with MS and 19 paired healthy con...
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Authors: Rasoanandrianina, H., Demortiere, S., Trabelsi, A., Ranjeva, J. P., Girard, O., Duhamel, G., Guye, M., Pelletier, J., Audoin, B., Callot, V. Tags: FUNCTIONAL Source Type: research

Cerebellar Watershed Injury in Children [PEDIATRICS]
CONCLUSIONS: In a series of patients with findings similar in appearance to the recently described bottom-of-fissure dysplasia, we have demonstrated a stereotyped pattern of injury attributable to cerebellar watershed injury. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Authors: Wright, J. N., Shaw, D. W. W., Ishak, G., Doherty, D., Perez, F. Tags: PEDIATRICS Source Type: research

The Perirolandic Sign: A Unique Imaging Finding Observed in Association with Polymerase {gamma}-Related Disorders [PEDIATRICS]
In this report, we describe brain MR imaging findings and electroencephalogram correlates of 13 children with POLG-related disorders at diagnosis and follow-up. At diagnosis, all patients had seizures and 12 had abnormal MR imaging findings. The most common imaging findings were unilateral or bilateral perirolandic (54%) and unilateral or bilateral thalamic signal changes (77%). Association of epilepsia partialis continua with perirolandic and thalamic signal changes was present in 86% and 70% of the patients, respectively. The occipital lobe was affected in 2 patients. On follow-up, 92% of the patients had disease progres...
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Authors: Goncalves, F. G., Hill, B., Guo, Y., Muraresku, C. C., McCormick, E., Alves, C. A. P. F., Teixeira, S. R., Martin-Saavedra, J. S., Zolkipli-Cunningham, Z., Falk, M. J., Vossough, A., Goldstein, A., Zuccoli, G. Tags: PEDIATRICS Source Type: research

Utility of Pre-Hematopoietic Cell Transplantation Sinus CT Screening in Children and Adolescents [PEDIATRICS]
BACKGROUND AND PURPOSE: The clinical benefit of pre-hematopoietic cell transplantation sinus CT screening remains uncertain, while the risks of CT radiation and anesthesia are increasingly evident. We sought to re-assess the impact of screening sinus CT on pretransplantation patient management and prediction of posttransplantation invasive fungal rhinosinusitis. MATERIALS AND METHODS: Pretransplantation noncontrast screening sinus CTs for 100 consecutive patients (mean age, 11.9 ± 5.5 years) were graded for mucosal thickening (Lund-Mackay score) and for signs of noninvasive or invasive fungal rhinosinusitis (sinus ...
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Authors: Harreld, J. H., Kaufman, R. A., Kang, G., Maron, G., Mitchell, W., Thompson, J. W., Srinivasan, A. Tags: PEDIATRICS Source Type: research

Neuroimaging Findings in Children with Constitutional Mismatch Repair Deficiency Syndrome [PEDIATRICS]
CONCLUSIONS: On brain MR imaging, these patients have both highly characteristic intra-axial tumors (typically multifocal high-grade gliomas) and nonspecific findings, some of which might represent early stages of neoplastic transformation. The incidence of developmental venous anomalies is high in these patients for unclear reasons. Awareness of these imaging findings, especially in combination, is important to raise the suspicion of constitutional mismatch repair deficiency in routine diagnostic imaging evaluation or surveillance imaging studies of asymptomatic carriers because early identification of the phenotypic &quo...
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Authors: Kerpel, A., Yalon, M., Soudack, M., Chiang, J., Gajjar, A., Nichols, K. E., Patay, Z., Shrot, S., Hoffmann, C. Tags: PEDIATRICS Source Type: research

Balanced Steady-State Free Precession Techniques Improve Detection of Residual Germ Cell Tumor for Treatment Planning [PEDIATRICS]
BACKGROUND AND PURPOSE: Identification of a partial/complete chemotherapy response in pediatric patients with intracranial germ cell tumors is clinically important for radiation treatment and management. Partial/complete response is conventionally determined on postcontrast MR imaging sequences. The purpose of this study was to assess the diagnostic utility of a balanced steady-state free precession sequence as an adjunct to standard MR imaging sequences for the detection of residual tumor in pediatric patients on postchemoreduction pre–radiation planning MR imaging. MATERIALS AND METHODS: This was a retrospective s...
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Authors: Mehan, W. A., Buch, K., Brasz, M. F., Simonis, F. F. J., MacDonald, S., Rincon, S., Kirsch, J. E., Caruso, P. Tags: PEDIATRICS Source Type: research

Disrupted Functional and Structural Connectivity in Angelman Syndrome [FUNCTIONAL]
CONCLUSIONS: This integrated quantitative MR imaging analysis demonstrated poor functional and structural connectivity, as well as brain volume reduction, in children with AS, which may explain the motor and language dysfunction observed in this well-characterized neurobehavioral phenotype. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - May 15, 2020 Category: Radiology Authors: Yoon, H. M., Jo, Y., Shim, W. H., Lee, J. S., Ko, T. S., Koo, J. H., Yum, M. S. Tags: FUNCTIONAL Source Type: research