Celebrating 35 Years of the AJNR: July 1984 edition [35 YEARS AGO IN AJNR]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Tags: 35 YEARS AGO IN AJNR Source Type: research

Subject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug Delivery [FUNCTIONAL]
CONCLUSIONS: Lordosis, kyphosis, and spinal cord eccentricity in the healthy human spine result in subject-specific patterns of bulk flow recirculating regions. The extent of the interconnectivity of the streamlines among these recirculating regions is fundamental in determining the long-term transport of solute particles along the spinal canal. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Coenen, W., Gutierrez-Montes, C., Sincomb, S., Criado-Hidalgo, E., Wei, K., King, K., Haughton, V., Martinez-Bazan, C., Sanchez, A. L., Lasheras, J. C. Tags: FUNCTIONAL Source Type: research

Quantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient Population [PEDIATRICS]
BACKGROUND AND PURPOSE: The purpose of the study is to characterize diffusion tensor imaging indices in the developing spinal cord, evaluating differences based on age and cord region. Describing the progression of DTI indices in the pediatric cord increases our understanding of spinal cord development. MATERIALS AND METHODS: A retrospective analysis was performed on DTI acquired in 121 pediatric patients (mean, 8.6 years; range, 0.3–18.0 years) at Monroe Carell Jr. Children's Hospital at Vanderbilt from 2017 to 2018. Diffusion-weighted images (15 directions; b = 750 s/mm2; slice thickness, 5 mm; in-plane resolution...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Reynolds, B. B., By, S., Weinberg, Q. R., Witt, A. A., Newton, A. T., Feiler, H. R., Ramkorun, B., Clayton, D. B., Couture, P., Martus, J. E., Adams, M., Wellons, J. C., Smith, S. A., Bhatia, A. Tags: PEDIATRICS Source Type: research

Predictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in Children [PEDIATRICS]
CONCLUSIONS: MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction. 3D rotational angiography–MR imaging fusion increases the diagnostic confidence regarding brain AVM recurrence and is therefore suited for intraoperative neuronavigation. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Jhaveri, A., Amirabadi, A., Dirks, P., Kulkarni, A. V., Shroff, M. M., Shkumat, N., Krings, T., Pereira, V. M., Rea, V., Muthusami, P. Tags: PEDIATRICS Source Type: research

Quantitative Analysis of Punctate White Matter Lesions in Neonates Using Quantitative Susceptibility Mapping and R2* Relaxation [FUNCTIONAL]
BACKGROUND AND PURPOSE: It is difficult to distinguish punctate white matter lesions from focal hemorrhagic lesions in neonates on conventional MR imaging because both kinds of lesions show increased signal intensity on T1-weighted images and, frequently, decreased signal intensity on T2-weighted images. Our aim was to distinguish punctate white matter lesions and focal hemorrhagic lesions using quantitative measures. MATERIALS AND METHODS: In the current study, we acquired multiecho gradient recalled-echo MR imaging data from 24 neonates with hypoxic-ischemic encephalopathy and postprocessed them as R2* relaxation maps a...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Zhang, Y., Rauscher, A., Kames, C., Weber, A. M. Tags: FUNCTIONAL Source Type: research

Functional Connectivity Associated with Health-Related Quality of Life in Children with Focal Epilepsy [FUNCTIONAL]
CONCLUSIONS: Our findings indicate that there are other higher order brain functions beyond cognition, which may be linked with functional connectivity of the brain. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Nawani, H., Smith, M. L., Wheeler, A. L., Widjaja, E. Tags: FUNCTIONAL Source Type: research

Comparison of Carotid Endarterectomy and Stenting for Symptomatic Internal Carotid Artery Near-Occlusion [INTERVENTIONAL]
CONCLUSIONS: Carotid artery stenting shows similar outcomes in restenosis and vessel maturation rates compared with carotid endarterectomy for ICA near-occlusion. There were no major differences between the 2 treatments in clinical outcomes or periprocedural complications. Carotid artery stenting is a revascularization option for carotid near-occlusion if the patient is considered at high risk for carotid endarterectomy. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Kim, J., Male, S., Damania, D., Jahromi, B. S., Tummala, R. P. Tags: INTERVENTIONAL Source Type: research

Antiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-Analysis [INTERVENTIONAL]
CONCLUSIONS: Overall, the incidence of delayed cerebral ischemia seems not to be significantly reduced among the antiplatelet therapy group. However, delayed cerebral ischemia tended to be lower among subjects with both long-term antiplatelet therapy and endovascular treatment and antiplatelet administration. Poor outcome and mortality rates were significantly reduced among the antiplatelet therapy group. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Cagnazzo, F., Derraz, I., Lefevre, P.- H., Gascou, G., Dargazanli, C., Riquelme, C., Perrini, P., di Carlo, D., Bonafe, A., Costalat, V. Tags: INTERVENTIONAL Source Type: research

Flow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second Angiography [INTERVENTIONAL]
SUMMARY: Traditional digital subtraction angiography provides rather limited evaluation of contrast flow dynamics when studying and treating intracranial brain aneurysms. A 1000-frames-per-second photon-counting x-ray detector was used to image detailed iodine-contrast flow patterns in an internal carotid artery aneurysm of a 3D-printed vascular phantom. High-speed imaging revealed differences in vortex and inflow patterns with and without a Pipeline Embolization Device flow diverter in more detail and clarity than could be seen in standard pulsed angiography. Improved temporal imaging has the potential to impact the outco...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Krebs, J. M., Shankar, A., Setlur Nagesh, S. V., Davies, J. M., Snyder, K. V., Levy, E. I., Hopkins, L. N., Mokin, M., Bednarek, D. R., Siddiqui, A. H., Rudin, S. Tags: INTERVENTIONAL Source Type: research

Long-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral Aneurysms [INTERVENTIONAL]
CONCLUSIONS: Aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Murakami, T., Nishida, T., Asai, K., Kadono, Y., Nakamura, H., Fujinaka, T., Kishima, H. Tags: INTERVENTIONAL Source Type: research

Diagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal Enhancement [ADULT BRAIN]
BACKGROUND AND PURPOSE: Leptomeningeal enhancement can be found in a variety of neurologic diseases such as Susac Syndrome. Our aim was to assess its prevalence and significance of leptomeningeal enhancement in Susac syndrome using 3T postcontrast fluid-attenuated inversion recovery MR imaging. MATERIALS AND METHODS: From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomening...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Coulette, S., Lecler, A., Saragoussi, E., Zuber, K., Savatovsky, J., Deschamps, R., Gout, O., Sabben, C., Aboab, J., Affortit, A., Charbonneau, F., Obadia, M. Tags: ADULT BRAIN Source Type: research

Impact of Skull Defects on the Role of CTA for Brain Death Confirmation [ADULT BRAIN]
This study aimed to evaluate the impact of a skull defect and the interpretation criteria of images on this diagnostic test. MATERIALS AND METHODS: A series of consecutive patients with a clinical diagnosis of brain death underwent CTA (case group), while the control group comprised patients with acute ischemic stroke in the same period. CTA criteria adopted to confirm brain death were the absence of opacification of the M4 branches and internal cerebral veins. The evaluation also included the presence of "stasis filling." Cases were stratified as intact skull, craniotomy, and craniectomy. Three neuroradiologist...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Nunes, D. M., Maia, A. C. M., Boni, R. C., da Rocha, A. J. Tags: ADULT BRAIN Source Type: research

Improving Detection of Multiple Sclerosis Lesions in the Posterior Fossa Using an Optimized 3D-FLAIR Sequence at 3T [ADULT BRAIN]
CONCLUSIONS: An optimized 3D-FLAIR sequence improved posterior fossa lesion detection in patients with MS. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Lecler, A., El Sanharawi, I., El Methni, J., Gout, O., Koskas, P., Savatovsky, J. Tags: ADULT BRAIN Source Type: research

Comparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRI [ADULT BRAIN]
BACKGROUND AND PURPOSE: Our aims were the following: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. MATERIALS AND METHODS: Multicontrast 3T and 7T MR images from 10 participants with relapsing-remitting MS and 10 with secondary-progressive MS. We used the following 3T contrast sequences: 3D-T1-weighted, quantitative T1, FLAIR, magnetization-transfer, and 2D pr...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Maranzano, J., Dadar, M., Rudko, D. A., De Nigris, D., Elliott, C., Gati, J. S., Morrow, S. A., Menon, R. S., Collins, D. L., Arnold, D. L., Narayanan, S. Tags: ADULT BRAIN Source Type: research

Normal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum Disorder [ADULT BRAIN]
CONCLUSIONS: We have shown that the damage in cerebellar normal-appearing white matter and normal-appearing gray matter is associated with aquaporin-4–mediated primary damage or axonal degeneration secondary to spinal lesions or both. The etiologic classifications of substructure-specific occult cerebellar damage may facilitate developing neuroimaging markers for assessing the severity and the results of therapy of neuromyelitis optica spectrum disorder occult cerebellar damage. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Sun, J., Zhang, N., Wang, Q., Zhang, X., Qin, W., Yang, L., Shi, F.- D., Yu, C. Tags: ADULT BRAIN Source Type: research

Extent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular Subtype [ADULT BRAIN]
BACKGROUND AND PURPOSE: Diffuse lower-grade gliomas are classified into prognostically meaningful molecular subtypes. We aimed to determine the impact of surgical resection on overall survival in lower-grade glioma molecular subtypes. MATERIALS AND METHODS: For 172 patients with lower-grade gliomas (World Health Organization grade II or III), pre- and postsurgical glioma volumes were determined using a semiautomated segmentation software based on FLAIR or T2-weighted MR imaging sequences. The association of pre- and postsurgical glioma volume and the percentage of glioma resection with overall survival was determined for ...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Patel, S. H., Bansal, A. G., Young, E. B., Batchala, P. P., Patrie, J. T., Lopes, M. B., Jain, R., Fadul, C. E., Schiff, D. Tags: ADULT BRAIN Source Type: research

Brain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI Techniques [ADULT BRAIN]
BACKGROUND AND PURPOSE: Postgadolinium MR imaging is crucial for brain tumor diagnosis and morphometric assessment. We compared brain tumor enhancement visualization and the "target" object morphometry obtained with the most commonly used 3D MR imaging technique, MPRAGE, with 2 other routinely available techniques: sampling perfection with application-optimized contrasts by using different flip angle evolutions (SPACE) and volumetric interpolated brain examination (VIBE). MATERIALS AND METHODS: Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniq...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Danieli, L., Riccitelli, G. C., Distefano, D., Prodi, E., Ventura, E., Cianfoni, A., Kaelin-Lang, A., Reinert, M., Pravata, E. Tags: ADULT BRAIN Source Type: research

Quantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor Trial [ADULT BRAIN]
CONCLUSIONS: This study shows that dT1 can predict early progression comparable with the standard method but offers the potential for substantial time and cost savings for clinical trials. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Schmainda, K. M., Prah, M. A., Zhang, Z., Snyder, B. S., Rand, S. D., Jensen, T. R., Barboriak, D. P., Boxerman, J. L. Tags: ADULT BRAIN Source Type: research

Association of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA Stenosis [FUNCTIONAL]
CONCLUSIONS: Fractional flow measured on 3D-TOF-MRA may serve as a noninvasive and practical tool for determining the cerebral hypoperfusion in patents with symptomatic MCA stenosis. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Ge, X., Zhao, H., Zhou, Z., Li, X., Sun, B., Wu, H., Wan, J., Xu, J., Villablanca, J. P., Liu, X. Tags: FUNCTIONAL Source Type: research

Assessing Postconcussive Reaction Time Using Transport-Based Morphometry of Diffusion Tensor Images [FUNCTIONAL]
BACKGROUND AND PURPOSE: Cognitive deficits are among the most commonly reported post-concussive symptoms, yet the underlying microstructural injury is poorly understood. Our aim was to discover white matter injury underlying reaction time in mild traumatic brain injury DTI by applying transport-based morphometry. MATERIALS AND METHODS: In this retrospective study, we performed DTI on 64 postconcussive patients (10–28 years of age; 69% male, 31% female) between January 2006 and March 2013. We measured the reaction time percentile by using Immediate Post-Concussion Assessment and Cognitive Testing. Using the 3D transp...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Kundu, S., Ghodadra, A., Fakhran, S., Alhilali, L. M., Rohde, G. K. Tags: FUNCTIONAL Source Type: research

Gadolinium Enhancement of the Aneurysm Wall in Unruptured Intracranial Aneurysms Is Associated with an Increased Risk of Aneurysm Instability: A Follow-Up Study [ADULT BRAIN]
CONCLUSIONS: Gadolinium enhancement of the aneurysm wall on MR imaging is associated with an increased risk of aneurysm instability. The absence of wall enhancement makes it unlikely that the aneurysm will grow or rupture in the short term. Larger studies are needed to investigate whether aneurysm wall enhancement is an independent predictor of aneurysm instability. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Vergouwen, M. D. I., Backes, D., van der Schaaf, I. C., Hendrikse, J., Kleinloog, R., Algra, A., Rinkel, G. J. E. Tags: ADULT BRAIN Source Type: research

Wall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRI [ADULT BRAIN]
CONCLUSIONS: Two distinct aneurysm wall microstructures responsible for gadolinium enhancement not depictable at lower spatial resolutions can be visualized in vivo using high-resolution gadolinium-enhanced 7T MR imaging. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Sato, T., Matsushige, T., Chen, B., Gembruch, O., Dammann, P., Jabbarli, R., Forsting, M., Junker, A., Maderwald, S., Quick, H. H., Ladd, M. E., Sure, U., Wrede, K. H. Tags: ADULT BRAIN Source Type: research

3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal Forebrain [ADULT BRAIN]
CONCLUSIONS: Direct identification of basal forebrain structures in multiple planes using the TSE T2 sequence makes this challenging neuroanatomy more accessible to practicing neuroradiologists. This protocol can be used to better define individual variations relevant to functional neurosurgical targeting and validate/complement advanced MR imaging methods being developed for direct visualization of these structures in living patients. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Hoch, M. J., Bruno, M. T., Faustin, A., Cruz, N., Mogilner, A. Y., Crandall, L., Wisniewski, T., Devinsky, O., Shepherd, T. M. Tags: ADULT BRAIN Source Type: research

Assessment of Explicitly Stated Interval Change on Noncontrast Head CT Radiology Reports [research-article]
BACKGROUND AND PURPOSE: Consistent and standardized reporting of interval change for certain diagnoses may improve the clinical utility of radiology reports. The purpose of this study was to assess explicitly stated interval change of various findings in noncontrast head CT reports. MATERIALS AND METHODS: A retrospective review was performed on successive noncontrast head CT radiology reports from the first 2 weeks of January 2014. Reports with at least 1 prior comparison CT scan were included. Reports with normal examination findings and those that made comparison with only other types of examinations (eg, MR imaging) we...
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Braileanu, M., Crawford, K., Key, S. R., Mullins, M. E. Tags: research-article Source Type: research

A Practical Review of Functional MRI Anatomy of the Language and Motor Systems [FUNCTIONAL]
SUMMARY: Functional MR imaging is being performed with increasing frequency in the typical neuroradiology practice; however, many readers of these studies have only a limited knowledge of the functional anatomy of the brain. This text will delineate the locations, anatomic boundaries, and functions of the cortical regions of the brain most commonly encountered in clinical practice—specifically, the regions involved in movement and language. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Hill, V. B., Cankurtaran, C. Z., Liu, B. P., Hijaz, T. A., Naidich, M., Nemeth, A. J., Gastala, J., Krumpelman, C., McComb, E. N., Korutz, A. W. Tags: FUNCTIONAL Source Type: research

[other]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Kavanagh, E. C. Tags: other Source Type: research

Erratum [ERRATA]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Tags: ERRATA Source Type: research

Automated Segmentation of Hippocampal Volume: The Next Step in Neuroradiologic Diagnosis of Mesial Temporal Sclerosis [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Damodaran, N. Tags: LETTERS Source Type: research

Reply: [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Kennedy, T. A. Tags: LETTERS Source Type: research

Optic Nerve Evaluation in Idiopathic Intracranial Hypertension [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: De Bernardo, M., Vitiello, L., Rosa, N. Tags: LETTERS Source Type: research

Polymer Embolism from Bioactive and Hydrogel Coil Embolization Technology: Considerations for Product Development [LETTERS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 8, 2019 Category: Radiology Authors: Chopra, A. M., Cruz, J. P., Hu, Y. C. Tags: LETTERS Source Type: research

Deep Learning-Based Automatic Segmentation of Lumbosacral Nerves on CT for Spinal Intervention: A Translational Study [SPINE]
CONCLUSIONS: Deep learning–based automatic segmentation of lumbosacral structures (nerves and bone) on routine CT is feasible, and SPINECT-based 3D reconstruction of safe and Kambin triangles is also validated. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Fan, G., Liu, H., Wu, Z., Li, Y., Feng, C., Wang, D., Luo, J., Wells, W. M., He, S. Tags: SPINE Source Type: research

Radiation Dose and Image Quality in Pediatric Neck CT [PEDIATRICS]
CONCLUSIONS: Images acquired with the low-dose CT protocols were deemed to be of sufficient quality for making a clinical diagnosis. Our initial results suggest that there may be an opportunity for further radiation dose reduction without compromising diagnostic image quality using iterative reconstruction algorithms. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Tipnis, S. V., Rieter, W. J., Patel, D., Stalcup, S. T., Matheus, M. G., Spampinato, M. V. Tags: PEDIATRICS Source Type: research

Radiologic and Pathologic Features of the Transmantle Sign in Focal Cortical Dysplasia: The T1 Signal Is Useful for Differentiating Subtypes [PEDIATRICS]
CONCLUSIONS: Approximately 6% (9/141) of this patient series had a T1-high-signal transmantle sign, and all were type IIb. The signal may reflect a rich density of balloon cells. This finding could support the differentiation of subtypes, especially type IIb. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Kimura, Y., Shioya, A., Saito, Y., Oitani, Y., Shigemoto, Y., Morimoto, E., Suzuki, F., Ikegaya, N., Kimura, Y., Iijima, K., Takayama, Y., Iwasaki, M., Sasaki, M., Sato, N. Tags: PEDIATRICS Source Type: research

Readout-Segmented Echo-Planar DWI for the Detection of Cholesteatomas: Correlation with Surgical Validation [HEAD & NECK]
CONCLUSIONS: Readout-segmented echo-planar DWI is a promising and reliable MR imaging sequence for the detection and exclusion of cholesteatoma. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Fischer, N., Schartinger, V. H., Dejaco, D., Schmutzhard, J., Riechelmann, H., Plaikner, M., Henninger, B. Tags: HEAD & amp; NECK Source Type: research

A Scoring System for Prediction of Cervical Lymph Node Metastasis in Patients with Head and Neck Squamous Cell Carcinoma [HEAD & NECK]
CONCLUSIONS: We developed a comprehensive and simple risk scoring system using CT characteristics in patients with head and neck squamous cell carcinoma to stratify the risk of lymph node metastasis. It could facilitate decision-making in daily practice. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Chung, M. S., Choi, Y. J., Kim, S. O., Lee, Y. S., Hong, J. Y., Lee, J. H., Baek, J. H. Tags: HEAD & amp; NECK Source Type: research

Evaluating the Utility of a Postprocessing Algorithm for MRI Evaluation of Optic Neuritis [HEAD & NECK]
The objective of this study was to determine whether a postprocessing algorithm selectively increases the contrast-to-noise ratio of abnormal optic nerves in optic neuritis, facilitating this diagnosis on MR imaging. MATERIALS AND METHODS: In this retrospective case-control study, coronal FLAIR images and coronal contrast-enhanced T1WI from 44 patients (31 eyes with clinically confirmed optic neuritis and 28 control eyes) underwent processing using a proprietary postprocessing algorithm designed to detect and visually highlight regions of contiguous increases in signal intensity by increasing the signal intensities of reg...
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Stunkel, L., Sharma, A., Parsons, M. S., Salter, A., Van Stavern, G. P. Tags: HEAD & amp; NECK Source Type: research

Localization of Parotid Gland Tumors in Relation to the Intraparotid Facial Nerve on 3D Double-Echo Steady-State with Water Excitation Sequence [HEAD & NECK]
BACKGROUND AND PURPOSE: Reliable preoperative facial nerve mapping may help avoid or minimize facial nerve injury during parotid tumor resection. The purpose of this study was to investigate the diagnostic performance of the 3D double-echo steady-state with water excitation sequence in localizing parotid gland tumors through direct visualization of the intraparotid facial nerve in comparison with indirect methods of estimating the facial nerve location. MATERIALS AND METHODS: We retrospectively reviewed 91 parotid gland tumors in 90 patients who underwent surgical resection and preoperative MR imaging, including the 3D do...
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Fujii, H., Fujita, A., Kanazawa, H., Sung, E., Sakai, O., Sugimoto, H. Tags: HEAD & amp; NECK Source Type: research

Dynamic Contrast-Enhanced MRI to Differentiate Parotid Neoplasms Using Golden-Angle Radial Sparse Parallel Imaging [HEAD & NECK]
BACKGROUND AND PURPOSE: Conventional imaging frequently shows overlapping features between benign and malignant parotid neoplasms. We investigated dynamic contrast-enhanced MR imaging using golden-angle radial sparse parallel imaging in differentiating parotid neoplasms. MATERIALS AND METHODS: For this retrospective study, 41 consecutive parotid neoplasms were imaged with dynamic contrast-enhanced MR imaging with golden-angle radial sparse parallel imaging using 1-mm in-plane resolution. The temporal resolution was 3.4 seconds for 78.2 seconds and 8.8 seconds for the remaining acquisition. Three readers retrospectively an...
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Mogen, J. L., Block, K. T., Bansal, N. K., Patrie, J. T., Mukherjee, S., Zan, E., Hagiwara, M., Fatterpekar, G. M., Patel, S. H. Tags: HEAD & amp; NECK Source Type: research

An Ultrasonographic Multiparametric Carotid Plaque Risk Index Associated with Cerebrovascular Symptomatology: A Study Comparing Color Doppler Imaging and Contrast-Enhanced Ultrasonography [EXTRACRANIAL VASCULAR]
BACKGROUND AND PURPOSE: Various ultrasonographic features of carortid plaques have been associated with the occurence of stroke, highlighting the need for multi-parametric assessment of plaque's vulnerability. Our aim was to compare ultrasonographic multiparametric indices using color Doppler imaging and contrast-enhanced sonography between symptomatic and asymptomatic carotid plaques. MATERIALS AND METHODS: This was a cross-sectional observational study recruiting 54 patients (72.2% male; median age, 61 years) undergoing sonography and contrast-enhanced sonography. Patients were included if a moderately or severely steno...
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Rafailidis, V., Chryssogonidis, I., Xerras, C., Grisan, E., Cheimariotis, G.- A., Tegos, T., Rafailidis, D., Sidhu, P. S., Charitanti-Kouridou, A. Tags: EXTRACRANIAL VASCULAR Source Type: research

Histologic and Biomolecular Similarities in Healing between Aneurysms and Cutaneous Skin Wounds [INTERVENTIONAL]
SUMMARY: The poorly understood mechanisms of aneurysm healing contribute substantially to the pressing medical problem of coiled aneurysm recanalization. Using an established saccular aneurysm model, we developed an animal model system in rabbits to study aneurysm and skin wound healing concurrently in the same animal. We found treated aneurysm healing to be similar to skin wound healing both histologically and in biomarker gene and protein expression, but in a delayed fashion. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Ayers-Ringler, J. R., Khashim, Z., Ding, Y.- H., Kallmes, D. F., Kadirvel, R. Tags: INTERVENTIONAL Source Type: research

Current Hospital Demographics of Subarachnoid Hemorrhage Based on CT Angiography and 3D Rotational Angiography in a Neurosurgical Center [ADULT BRAIN]
CONCLUSIONS: This study provides robust data on hospital demographics of SAH in a neurosurgical referral center, based on CTA and 3D rotational angiography of all vessels. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: van Rooij, S. B. T., Bechan, R. S., van Rooij, W. J., Sprengers, M. E. Tags: ADULT BRAIN Source Type: research

First-Line Sofia Aspiration Thrombectomy Approach within the Endovascular Treatment of Ischemic Stroke Multicentric Registry: Efficacy, Safety, and Predictive Factors of Success [INTERVENTIONAL]
CONCLUSIONS: The first-line contact aspiration approach appeared safe and efficient with Sofia catheters. These devices achieved very high reperfusion rates with a low requirement for stent retriever rescue therapy, especially for M1 occlusions. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Marnat, G., Barreau, X., Detraz, L., Bourcier, R., Gory, B., Sgreccia, A., Gariel, F., Berge, J., Menegon, P., Kyheng, M., Labreuche, J., Consoli, A., Blanc, R., Lapergue, B., on behalf of the ETIS Investigators Tags: INTERVENTIONAL Source Type: research

Thrombectomy with Conscious Sedation Compared with General Anesthesia: A DEFUSE 3 Analysis [INTERVENTIONAL]
CONCLUSIONS: Patients who underwent thrombectomy with conscious sedation in the extended time window experienced a higher likelihood of functional independence at 90 days, a lower NIHSS score at 24 hours, and a shorter time from femoral puncture to reperfusion compared with those who had general anesthesia. This effect remained robust in institutions that only treated patients with a single anesthesia technique. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Powers, C. J., Dornbos, D., Mlynash, M., Gulati, D., Torbey, M., Nimjee, S. M., Lansberg, M. G., Albers, G. W., Marks, M. P. Tags: INTERVENTIONAL Source Type: research

Susceptibility-Weighted MR Imaging Hypointense Rim in Progressive Multifocal Leukoencephalopathy: The End Point of Neuroinflammation and a Potential Outcome Predictor [ADULT BRAIN]
CONCLUSIONS: The thin, uniformly linear, gyriform SWI-hypointense rim in the paralesional U-fibers in patients with definite progressive multifocal leukoencephalopathy might represent an end-point stage of the neuroinflammatory process in long-term survivors. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Thurnher, M. M., Boban, J., Rieger, A., Gelpi, E. Tags: ADULT BRAIN Source Type: research

Quantitative Susceptibility Mapping of Time-Dependent Susceptibility Changes in Multiple Sclerosis Lesions [ADULT BRAIN]
The objective of this study was to use quantitative susceptibility mapping to determine whether lesions with a hyperintense rim, indicative of iron-laden inflammatory cells (rim+), follow a unique time-dependent trajectory of susceptibility change compared with those without (rim–). MATERIALS AND METHODS: We studied patients with MS with at least 1 new gadolinium-enhancing lesion and at least 3 longitudinal quantitative susceptibility mapping scans obtained between 1.1 and 6.1 years. Lesions were classified as rim+ if a hyperintense rim appeared on quantitative susceptibility mapping at any time. A multilevel growth...
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Zhang, S., Nguyen, T. D., Hurtado Rua, S. M., Kaunzner, U. W., Pandya, S., Kovanlikaya, I., Spincemaille, P., Wang, Y., Gauthier, S. A. Tags: ADULT BRAIN Source Type: research

Association between Tumor Acidity and Hypervascularity in Human Gliomas Using pH-Weighted Amine Chemical Exchange Saturation Transfer Echo-Planar Imaging and Dynamic Susceptibility Contrast Perfusion MRI at 3T [FUNCTIONAL]
CONCLUSIONS: A positive linear correlation between CBV and acidity in areas of T2-hyperintense, nonenhancing tumor, but not enhancing tumor, was observed across patients. Local heterogeneity was observed within individual tumors. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Wang, Y.- L., Yao, J., Chakhoyan, A., Raymond, C., Salamon, N., Liau, L. M., Nghiemphu, P. L., Lai, A., Pope, W. B., Nguyen, N., Ji, M., Cloughesy, T. F., Ellingson, B. M. Tags: FUNCTIONAL Source Type: research

The Occipital Emissary Vein: A Possible Marker for Pseudotumor Cerebri [ADULT BRAIN]
BACKGROUND AND PURPOSE: Transverse sinus stenosis can lead to pseudotumor cerebri syndrome by elevating the cerebral venous pressure. The occipital emissary vein is an inconstant emissary vein that connects the torcular herophili with the suboccipital veins of the external vertebral plexus. This retrospective study compares the prevalence and size of the occipital emissary vein in patients with pseudotumor cerebri syndrome with those in healthy control subjects to determine whether the occipital emissary vein could represent a marker of pseudotumor cerebri syndrome. MATERIALS AND METHODS: The cranial venous system of 46 a...
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Hedjoudje, A., Piveteau, A., Gonzalez-Campo, C., Moghekar, A., Gailloud, P., San Millan, D. Tags: ADULT BRAIN Source Type: research

Baseline and Evolutionary Radiologic Features in Sporadic, Hemorrhagic Brain Cavernous Malformations [ADULT BRAIN]
CONCLUSIONS: Hemorrhagic cavernous malformation demonstrates a characteristic pattern of evolution on follow-up imaging. Knowing this evolution helps to analyze the timing of imaging in relation to the clinical presentation and may help distinguish true cavernous malformation hemorrhagic evolution from mimics and guide appropriate timing of interval-imaging follow-up after symptomatic bleeds in untreated patients. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Flemming, K. D., Kumar, S., Lanzino, G., Brinjikji, W. Tags: ADULT BRAIN Source Type: research

Surveillance of Unruptured Intracranial Saccular Aneurysms Using Noncontrast 3D-Black-Blood MRI: Comparison of 3D-TOF and Contrast-Enhanced MRA with 3D-DSA [INTERVENTIONAL]
CONCLUSIONS: 3D black-blood MR imaging achieves better accuracy for aneurysm size measurements compared with 3D-TOF, using 3D rotational angiography as a criterion standard. This noncontrast technique is promising for surveillance of unruptured intracranial aneurysms. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - June 12, 2019 Category: Radiology Authors: Zhu, C., Wang, X., Eisenmenger, L., Tian, B., Liu, Q., Degnan, A. J., Hess, C., Saloner, D., Lu, J. Tags: INTERVENTIONAL Source Type: research