Intra-Arterial Thrombolysis is Associated with Delayed Reperfusion of Remaining Vessel Occlusions following Incomplete Thrombectomy [INTERVENTIONAL]
CONCLUSIONS: Rescue intra-arterial thrombolytics is associated with delayed reperfusion of remaining vessel occlusions following incomplete mechanical thrombectomy. The value of intra-arterial thrombolytics as a potential therapy for incomplete reperfusions after mechanical thrombectomy should be assessed in the setting of randomized controlled trials. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Mujanovic, A., Kurmann, C. C., Serrallach, B. L., Dobrocky, T., Meinel, T. R., Windecker, D., Grunder, L., Beyeler, M., Seiffge, D. J., Pilgram-Pastor, S., Arnold, M., Piechowiak, E. I., Gralla, J., Fischer, U., Kaesmacher, J. Tags: INTERVENTIONAL Source Type: research

CT Perfusion Does Not Modify the Effect of Reperfusion in Patients with Acute Ischemic Stroke Undergoing Endovascular Treatment in the ESCAPE-NA1 Trial [INTERVENTIONAL]
CONCLUSIONS: CTP did not modify the effect of near-complete reperfusion on clinical outcomes. Thus, CTP cannot explain why some patients with near-complete reperfusion have poor clinical outcomes. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Rex, N. B., McDonough, R. V., Ospel, J. M., Kashani, N., Sehgal, A., Fladt, J. C., McTaggart, R. A., Nogueira, R., Menon, B., Demchuk, A. M., Tymianski, M., Hill, M. D., Goyal, M., on behalf of the ESCAPE-NA1 Investigators Tags: INTERVENTIONAL Source Type: research

Prospective Comparison of T1-SPACE and MPRAGE for the Identification of Intrinsic T1 Hyperintensity in Patients with Intracranial Melanoma Metastases [ADULT BRAIN]
CONCLUSIONS: Precontrast intrinsic T1 hyperintensity is more conspicuous with MPRAGE than T1-SPACE. In patients with metastatic melanoma, 3D-GRE should be preferred as the precontrast T1WI sequence when both 3D-TSE and 3D-GRE are performed postcontrast and when not administering IV contrast. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Lasocki, A., Stuckey, S. L., Caspersz, L., Xie, J., McArthur, G. A. Tags: ADULT BRAIN Source Type: research

Long-Term Follow-up of Multinodular and Vacuolating Neuronal Tumors and Implications for Surveillance Imaging [ADULT BRAIN]
CONCLUSIONS: MVNT segmentation across follow-up brain MR imaging examinations did not demonstrate significant volume differences, suggesting that these tumors do not enlarge with time. Hence, frequent surveillance imaging of newly diagnosed MVNTs may not be necessary. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Dogra, S., Zagzag, D., Young, M., Golfinos, J., Orringer, D., Jain, R. Tags: ADULT BRAIN Source Type: research

Longitudinal Changes in Cerebral Perfusion, Perivascular Space Volume, and Ventricular Volume in a Healthy Cohort Undergoing a Spaceflight Analog [ADULT BRAIN]
CONCLUSIONS: The patterns of change in brain physiology observed in healthy participants suggest a relationship between cerebral perfusion and CSF homeostasis. Further study is warranted to determine whether a causal relationship exists and whether similar neurophysiologic responses occur during spaceflight. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Tidwell, J. B., Taylor, J. A., Collins, H. R., Chamberlin, J. H., Barisano, G., Sepehrband, F., Turner, M. D., Gauthier, G., Mulder, E. R., Gerlach, D. A., Roberts, D. R. Tags: ADULT BRAIN Source Type: research

Deep Learning Segmentation of the Nucleus Basalis of Meynert on 3T MRI [ADULT BRAIN]
CONCLUSIONS: We developed the first model, to our knowledge, for automatic and accurate patient-specific segmentation of the nucleus basalis of Meynert. This model may enable further study into the nucleus, impacting new treatments such as deep brain stimulation. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Doss, D. J., Johnson, G. W., Narasimhan, S., Shless, J. S., Jiang, J. W., Gonzalez, H. F. J., Paulo, D. L., Lucas, A., Davis, K. A., Chang, C., Morgan, V. L., Constantinidis, C., Dawant, B. M., Englot, D. J. Tags: ADULT BRAIN Source Type: research

Generative Adversarial Network-Enhanced Ultra-Low-Dose [18F]-PI-2620 {tau} PET/MRI in Aging and Neurodegenerative Populations [ADULT BRAIN]
CONCLUSIONS: The clinical readings of deep learning–enhanced ultra-low-dose PET images were consistent with those performed with full-dose imaging, suggesting the possibility of reducing the dose and enabling more frequent examinations for dementia monitoring. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Chen, K. T., Tesfay, R., Koran, M. E. I., Ouyang, J., Shams, S., Young, C. B., Davidzon, G., Liang, T., Khalighi, M., Mormino, E., Zaharchuk, G. Tags: ADULT BRAIN Source Type: research

Trends of Diversity in Neuroradiology Trainees in United States 2015-2022 [research-article]
This study shows the relative trends specifically in neuroradiology trainees, and the need for reassessment and further steps to increase diversity. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Prajapati, P., Wu, X., Bajaj, S., Gandhi, D., Wintermark, M., Malhotra, A. Tags: research-article Source Type: research

Unpacking the CNS Manifestations of Epstein-Barr Virus: An Imaging Perspective [ADULT BRAIN]
SUMMARY: Epstein-Barr virus is a ubiquitous herpesvirus that may cause both infective (encephalitis, meningitis, and so forth) and postinfection inflammatory (such as Guillain-Barré syndrome, acute disseminated encephalomyelitis) manifestations in the CNS. Diagnosis of Epstein-Barr virus–related CNS pathologies is often complicated due to a nonspecific clinical presentation and overlap with other infectious and noninfectious causes, both clinically and on imaging. The Epstein-Barr virus is also implicated in several lymphoproliferative disorders in both immunocompromised and immunocompetent hosts. MR imaging i...
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Soni, N., Ora, M., Singh, R., Mehta, P., Agarwal, A., Bathla, G. Tags: ADULT BRAIN Source Type: research

Benign Enhancing Foramen Magnum Lesions [ADULT BRAIN]
We present the first case with pathologic correlation. These lesions are fibrotic nodules adhering to the spinal accessory nerve. While they can enlarge with time on subsequent examinations, on the basis of the imaging characteristics and location, they do not necessitate surgical resection. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Mark, I. T., Black, D., Benson, J. C., Campeau, N. G., Johnson, D. R., Messina, S. A., Giannini, C., Parney, I., Morris, P. P. Tags: ADULT BRAIN Source Type: research

Regarding "Automated Segmentation of Intracranial Thrombus on NCCT and CTA in Patients with Acute Ischemic Stroke Using a Coarse-to-Fine Deep Learning Model" [letter]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - September 11, 2023 Category: Radiology Authors: Tortora, M., Pacchiano, F. Tags: letter Source Type: research

Resisted Inspiration Improves Visualization of CSF-Venous Fistulas in Spontaneous Intracranial Hypotension [SPINE]
CONCLUSIONS: In patients with spontaneous intracranial hypotension, resisted inspiration improved visualization of CSF-venous fistulas in most, but not all, cases. Further investigation is needed to determine the impact of this technique on the overall diagnostic yield of myelography in this condition. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - August 9, 2023 Category: Radiology Authors: Kranz, P. G., Malinzak, M. D., Gray, L., Willhite, J., Amrhein, T. J. Tags: SPINE Source Type: research

Deep Learning-Generated Synthetic MR Imaging STIR Spine Images Are Superior in Image Quality and Diagnostically Equivalent to Conventional STIR: A Multicenter, Multireader Trial [SPINE]
CONCLUSIONS: Synthetically created STIR spine MR images were diagnostically interchangeable with acquired STIR, while providing significantly higher image quality, suggesting routine clinical practice potential. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - August 9, 2023 Category: Radiology Authors: Tanenbaum, L. N., Bash, S. C., Zaharchuk, G., Shankaranarayanan, A., Chamberlain, R., Wintermark, M., Beaulieu, C., Novick, M., Wang, L. Tags: SPINE Source Type: research

Posterior Fossa Horns in Hurler Syndrome: Prevalence and Regression [PEDIATRICS]
SUMMARY: Posterior fossa "horns" caused by internal hypertrophy of the occipitomastoid sutures are one of the more recently defined cranial abnormalities described in mucopolysaccharidoses, especially in Hurler Syndrome. However, details of this finding, including the development and natural history, are not well-understood. Two hundred eighty-six brain MR imaging studies of 61 patients with mucopolysaccharidosis I-Hurler syndrome treated at single institution between 1996 and 2015 were studied. Posterior fossa horn height was measured as the perpendicular distance from the tip of the horn to the expected curvature of the ...
Source: American Journal of Neuroradiology - August 9, 2023 Category: Radiology Authors: Huang, S., Hall, D., Nascene, D. Tags: PEDIATRICS Source Type: research

Epileptogenic Tubers Are Associated with Increased Kurtosis of Susceptibility Values: A Combined Quantitative Susceptibility Mapping and Stereoelectroencephalography Pilot Study [FUNCTIONAL]
CONCLUSIONS: Our finding of increased kurtosis of quantitative susceptibility mapping values (heavy-tailed distribution) was highly specific, suggesting that it may be a useful biomarker to identify putative epileptogenic tubers in tuberous sclerosis complex. This finding motivates the investigation of underlying tuber mineralization and other properties driving kurtosis changes in quantitative susceptibility mapping values. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - August 9, 2023 Category: Radiology Authors: Chari, A., Sedlacik, J., Seunarine, K., Piper, R. J., Hales, P., Shmueli, K., Mankad, K., Löbel, U., Eltze, C., Moeller, F., Scott, R. C., Tisdall, M. M., Cross, J. H., Carmichael, D. W. Tags: FUNCTIONAL Source Type: research