Correlation between Multiparametric MR Imaging and Molecular Genetics in Pontine Pediatric High-Grade Glioma [FUNCTIONAL]
CONCLUSIONS:
ADC histogram parameters are correlated with histone H3 mutation status in pontine pediatric high-grade glioma. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Rameh, V., Vajapeyam, S., Ziaei, A., Kao, P., London, W. B., Baker, S. J., Chiang, J., Lucas, J., Tinkle, C. L., Wright, K. D., Poussaint, T. Y. Tags: FUNCTIONAL Source Type: research
Association of Lower Age and Cardiorespiratory Events during Intra-Arterial Chemotherapy for Retinoblastoma: A Prospective Observational Study [INTERVENTIONAL]
CONCLUSIONS:
In children undergoing intra-arterial chemotherapy for retinoblastoma treatment, cardiorespiratory events were observed in 12.5% of procedures. Lower age was associated with this complication. Although predominantly mild, these events should have prompt diagnosis and treatment to prevent further deterioration and worse outcomes. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Lima, M. F., Teixeira, L. F., Teruya, S. B. d. M., Macedo, C. R. P. D., Pinto, V. M. d. S., Terra, T. A., Fonseca, J. R. F. Tags: INTERVENTIONAL Source Type: research
Exploratory Multisite MR Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children [FUNCTIONAL]
CONCLUSIONS:
Our pilot study suggests that MRSI differentiates GM and WM by NAA/Cr in this population, disease complications may lead to neuroaxonal loss in WM in children, and deeper investigation is warranted to further untangle how diabetic ketoacidosis and chronic hyperglycemia affect brain health and cognition in type 1 diabetes. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Cai, L. Y., Tanase, C., Anderson, A. W., Patel, N. J., Lee, C. A., Jones, R. S., LeStourgeon, L. M., Mahon, A., Taki, I., Juvera, J., Pruthi, S., Gwal, K., Ozturk, A., Kang, H., Rewers, A., Rewers, M. J., Alonso, G. T., Glaser, N., Ghetti, S., Jaser, S. S Tags: FUNCTIONAL Source Type: research
Perifocal Edema in Patients with Meningioma is Associated with Impaired Whole-Brain Connectivity as Detected by Resting-State fMRI [FUNCTIONAL]
CONCLUSIONS:
Resting-state fMRI showed a significant association between impaired functional connectivity and perifocal edema, but not tumor volume, in patients with meningiomas. We demonstrated that better neurocognitive function was associated with less impairment of functional connectivity. This result shows that our resting-state fMRI marker indicates a detrimental influence of peritumoral brain edema on global functional connectivity in patients with meningiomas. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Stoecklein, V. M., Wunderlich, S., Papazov, B., Thon, N., Schmutzer, M., Schinner, R., Zimmermann, H., Liebig, T., Ricke, J., Liu, H., Tonn, J.- C., Schichor, C., Stoecklein, S. Tags: FUNCTIONAL Source Type: research
Early Detection of Underlying Cavernomas in Patients with Spontaneous Acute Intracerebral Hematomas [ADULT BRAIN]
CONCLUSIONS:
An imaging model including ovoid/spherical shape, regular margins, absence of extralesional hemorrhage, and absence of peripheral rim enhancement accurately identifies cavernoma-related acute spontaneous cerebral hematomas in young patients. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Bani-Sadr, A., Eker, O. F., Cho, T.- H., Ameli, R., Berhouma, M., Cappucci, M., Derex, L., Mechtouff, L., Meyronet, D., Nighoghossian, N., Berthezene, Y., Hermier, M. Tags: ADULT BRAIN Source Type: research
MR Imaging Findings in a Large Population of Autoimmune Encephalitis [ADULT BRAIN]
CONCLUSIONS:
Sixty-one percent of patients with autoimmune encephalitis had abnormal brain MR imaging findings at symptom onset, most commonly involving the limbic system. Susceptibility artifact is rare and makes autoimmune encephalitis less likely as a diagnosis. Brainstem and cerebellar involvement were more common in group 1, while leptomeningeal enhancement was more common in group 2. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Gillon, S., Chan, M., Chen, J., Guterman, E. L., Wu, X., Glastonbury, C. M., Li, Y. Tags: ADULT BRAIN Source Type: research
Sex-Specific Patterns of Cerebral Atrophy and Enlarged Perivascular Spaces in Patients with Cerebral Amyloid Angiopathy and Dementia [ADULT BRAIN]
CONCLUSIONS:
Medial temporal lobe atrophy was more prominent in men with dementia, whereas women showed a higher number of enlarged perivascular spaces in the centrum semiovale. Overall, this finding suggests differential pathophysiologic mechanisms with sex-specific neuroimaging patterns in cerebral amyloid angiopathy. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Pinho, J., Almeida, F. C., Araujo, J. M., Machado, A., Costa, A. S., Silva, F., Francisco, A., Quintas-Neves, M., Ferreira, C., Soares-Fernandes, J. P., Oliveira, T. G. Tags: ADULT BRAIN Source Type: research
Cost-Effectiveness Analysis of 68Ga-DOTATATE PET/MRI in Radiotherapy Planning in Patients with Intermediate-Risk Meningioma [ADULT BRAIN]
CONCLUSIONS:
68Ga-DOTATATE PET/MR imaging as an adjunct imaging technique is cost-effective in postoperative treatment planning in patients with meningiomas. Most important, the model results show that the sensitivity and specificity cost-effective thresholds of 68Ga-DOTATATE PET/MR imaging could be attained in clinical practice. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Rodriguez, J., Martinez, G., Mahase, S., Roytman, M., Haghdel, A., Kim, S., Madera, G., Magge, R., Pan, P., Ramakrishna, R., Schwartz, T. H., Pannullo, S. C., Osborne, J. R., Lin, E., Knisely, J. P. S., Sanelli, P. C., Ivanidze, J. Tags: ADULT BRAIN Source Type: research
Choroid Plexus Calcification Correlates with Cortical Microglial Activation in Humans: A Multimodal PET, CT, MRI Study [FUNCTIONAL]
CONCLUSIONS:
Choroid plexus calcification can be accurately and automatically quantified using low-dose CT and MRI. Choroid plexus calcification—but not choroid plexus volume—predicted cortical inflammation. Previously unmeasured choroid plexus calcium may explain recent reports of choroid plexus enlargement in human inflammatory and other diseases. Choroid plexus calcification may be a specific and relatively easily acquired biomarker for neuroinflammation and choroid plexus pathology in humans. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Butler, T., Wang, X. H., Chiang, G. C., Li, Y., Zhou, L., Xi, K., Wickramasuriya, N., Tanzi, E., Spector, E., Ozsahin, I., Mao, X., Razlighi, Q. R., Fung, E. K., Dyke, J. P., Maloney, T., Gupta, A., Raj, A., Shungu, D. C., Mozley, P. D., Rusinek, H., Glod Tags: FUNCTIONAL Source Type: research
Investigation of Brain Iron in Niemann-Pick Type C: A 7T Quantitative Susceptibility Mapping Study [FUNCTIONAL]
CONCLUSIONS:
Our findings suggest iron deposition in the pulvinar nucleus in Niemann-Pick type C disease, which is associated with thalamic atrophy and disease severity. This preliminary evidence supports the link between iron and neurodegeneration in Niemann-Pick type C, in line with existing literature on other neurodegenerative disorders. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Ravanfar, P., Syeda, W. T., Rushmore, R. J., Moffat, B., Lyall, A. E., Merritt, A. H., Devenyi, G. A., Chakravarty, M. M., Desmond, P., Cropley, V. L., Makris, N., Shenton, M. E., Bush, A. I., Velakoulis, D., Pantelis, C., Walterfang, M. Tags: FUNCTIONAL Source Type: research
Crowd-Sourced Deep Learning for Intracranial Hemorrhage Identification: Wisdom of Crowds or Laissez-Faire [ADULT BRAIN]
CONCLUSIONS:
None of the ensemble learning methods outperformed the accuracy of the single best convolutional neural network, at least in the context of intracranial hemorrhage detection. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Hofmeijer, E. I. S., Tan, C. O., van der Heijden, F., Gupta, R. Tags: ADULT BRAIN Source Type: research
Realistic Productivity in Academic Neuroradiology: A National Survey of Neuroradiology Division Chiefs [EDITORIALS]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Wintermark, M., Gupta, V., Hess, C., Lee, R., Maldjian, J., Mukherjee, S., Mukherji, S., Seidenwurm, D., Kennedy, T. Tags: EDITORIALS Source Type: research
Advances in Acute Ischemic Stroke Treatment: Current Status and Future Directions [ADULT BRAIN]
SUMMARY:
The management of acute ischemic stroke has undergone a paradigm shift in the past decade. This has been spearheaded by the emergence of endovascular thrombectomy, along with advances in medical therapy, imaging, and other facets of stroke care. Herein, we present an updated review of the various stroke trials that have impacted and continue to transform stroke management. It is critical for the radiologist to stay abreast of the ongoing developments to provide meaningful input and remain a useful part of the stroke team. (Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Bathla, G., Ajmera, P., Mehta, P. M., Benson, J. C., Derdeyn, C. P., Lanzino, G., Agarwal, A., Brinjikji, W. Tags: ADULT BRAIN Source Type: research
Perspectives [other]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Arora, A. Tags: other Source Type: research
Erratum [ERRATA]
(Source: American Journal of Neuroradiology)
Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Tags: ERRATA Source Type: research
