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Total 1715 results found since Jan 2013.

Automated segmentation of chronic stroke lesions using LINDA: Lesion identification with neighborhood data analysis
Abstract The gold standard for identifying stroke lesions is manual tracing, a method that is known to be observer dependent and time consuming, thus impractical for big data studies. We propose LINDA (Lesion Identification with Neighborhood Data Analysis), an automated segmentation algorithm capable of learning the relationship between existing manual segmentations and a single T1‐weighted MRI. A dataset of 60 left hemispheric chronic stroke patients is used to build the method and test it with k‐fold and leave‐one‐out procedures. With respect to manual tracings, predicted lesion maps showed a mean dice overlap of...
Source: Human Brain Mapping - January 1, 2016 Category: Neurology Authors: Dorian Pustina, H. Branch Coslett, Peter E. Turkeltaub, Nicholas Tustison, Myrna F. Schwartz, Brian Avants Tags: Research Article Source Type: research

Effectiveness of motor imagery or mental practice in functional recovery after stroke: a systematic review
Conclusions MP is effective when used in conjunction with conventional physical therapy for functional rehabilitation of both upper and lower limbs, as well as for the recovery of daily activities and skills. Owing to the heterogeneity of the studies with regard to the intervention protocol, specific imagery technique, time spent practicing, patient characteristics, etc., more studies are needed in order to determine the optimal treatment protocol and patient profile.
Source: Neurologia - January 13, 2016 Category: Neurology Source Type: research

The inclination for conscious motor control after stroke: validating the Movement-Specific Reinvestment Scale for use in inpatient stroke patients.
CONCLUSIONS: The MSRS is a valid and reliable tool and suitable to assess the relationship between reinvestment and motor recovery in the first months post-stroke. Eventually, this may help therapists to individualize motor learning interventions based on patients' reinvestment preferences. Implications for rehabilitation This study showed that the Movement-Specific Reinvestment Scale (MSRS) is a valid and reliable tool to objectify stroke patients' inclination for conscious motor control. The MSRS may be used to identify stroke patients who are strongly inclined to consciously control their movements, as this disposition ...
Source: Disability and Rehabilitation - January 10, 2016 Category: Rehabilitation Authors: Kal E, Houdijk H, Van Der Wurff P, Groet E, Van Bennekom C, Scherder E, Van der Kamp J Tags: Disabil Rehabil Source Type: research

The role of learning in improving functional writing in stroke aphasia.
CONCLUSIONS: These results show that small doses of writing therapy can lead to large gains in specific types of writing. These gains did not extend to improvements in frequency of writing in daily living, nor ecological measures of email writing. There is a need to develop bridging interventions between experimental tasks towards more multi-faceted and ecological everyday writing tasks. Implications for Rehabilitation Acquired dysgraphia can restrict people from participating in social, educational and professional life. This study has shown that copy and recall spelling therapies can improve the spelling of treated words...
Source: Disability and Rehabilitation - January 5, 2016 Category: Rehabilitation Authors: Thiel L, Sage K, Conroy P Tags: Disabil Rehabil Source Type: research

Sensors, Vol. 16, Pages 134: A Machine Learning Framework for Gait Classification Using Inertial Sensors: Application to Elderly, Post-Stroke and Huntington’s Disease Patients
Machine learning methods have been widely used for gait assessment through the estimation of spatio-temporal parameters. As a further step, the objective of this work is to propose and validate a general probabilistic modeling approach for the classification of different pathological gaits. Specifically, the presented methodology was tested on gait data recorded on two pathological populations (Huntington’s disease and post-stroke subjects) and healthy elderly controls using data from inertial measurement units placed at shank and waist. By extracting features from group-specific Hidden Markov Models (HMMs) and signal in...
Source: Sensors - January 21, 2016 Category: Biotechnology Authors: Andrea ManniniDiana TrojanielloAndrea CereattiAngelo Sabatini Tags: Article Source Type: research

Depressive symptoms influence use of feedback for motor learning and recovery in chronic stroke.
CONCLUSION: The presence of PSD diminished the ability to use auditory feedback for arm motor recovery and motor learning. PMID: 26444639 [PubMed - in process]
Source: Restorative Neurology and Neuroscience - January 25, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Motor imagery learning across a sequence of trials in stroke patients.
CONCLUSIONS: Trial-dependent changes during motor imagery learning presented in a different manner in stroke patients. Understanding motor imagery learning in stroke patients is crucial for enhancing the effectiveness of motor-imagery-based BCIs. PMID: 26410210 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - January 25, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Using stroke thrombolysis to describe the role of repetition in learning a cognitive skill
ConclusionsAccruing sufficient experience of a new cognitive clinical skill can be challenging for independent physicians, with expertise gradually emerging in a largely linear fashion only after much repetition.
Source: Medical Education - January 26, 2016 Category: Universities & Medical Training Authors: Christopher A K Y Chong Tags: Repetition ‐Based Learning Source Type: research

The effect of sleep on motor learning in the aging and stroke population - a systematic review.
Authors: Backhaus W, Kempe S, Hummel FC Abstract There is extensive evidence for positive effects of sleep on motor learning in young individuals; however, the effects of sleep on motor learning in people with stroke and in healthy older individuals are not well understood. The aim of this systematic review was to quantify the association between sleep and procedural memory performance - a marker for motor learning - in healthy older people and people with stroke. After searches in PubMed, Medline and Embase fourteen studies, including 44 subjects after stroke and 339 healthy older participants were included. Overa...
Source: Restorative Neurology and Neuroscience - February 4, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Identification of the factors conditioning times and indicators of quality in the intrahospital care of acute stroke.
CONCLUSIONS: Knowledge of the current situation of the times and quality indicators and their determinants are essential to provide the motivation to start an initiative to improve the quality of care in patients with acute stroke. PMID: 26860720 [PubMed - in process]
Source: Revista de Neurologia - February 12, 2016 Category: Neurology Authors: Palazon-Cabanes B, Lopez-Picazo Ferrer JJ, Morales-Ortiz A, Tomas-Garcia N Tags: Rev Neurol Source Type: research

RPS Wales calls for pharmacists to raise awareness of mini stroke
The Royal Pharmaceutical Society in Wales (RPS Wales) is calling for pharmacists to use their skills to educate patients on the risks factors that can cause a stroke and to help patients with these risks to learn the early warning signs so they can act and act fast.   T
Source: Royal Pharmaceutical Society News - April 30, 2014 Category: Drugs & Pharmacology Source Type: news

Dorsal premotor activity and connectivity relate to action selection performance after stroke
Abstract Compensatory activation in dorsal premotor cortex (PMd) during movement execution has often been reported after stroke. However, the role of PMd in the planning of skilled movement after stroke has not been well studied. The current study investigated the behavioral and neural response to the addition of action selection (AS) demands, a motor planning process that engages PMd in controls, to movement after stroke. Ten individuals with chronic, left hemisphere stroke and 16 age‐matched controls made a joystick movement with the right hand under two conditions. In the AS condition, participants moved right or left...
Source: Human Brain Mapping - February 15, 2016 Category: Neurology Authors: Jill Campbell Stewart, Pritha Dewanjee, Umar Shariff, Steven C. Cramer Tags: Research Article Source Type: research

Defining Optimal Aerobic Exercise Parameters to Affect Complex Motor and Cognitive Outcomes after Stroke: A Systematic Review and Synthesis.
Abstract Although poststroke aerobic exercise (AE) increases markers of neuroplasticity and protects perilesional tissue, the degree to which it enhances complex motor or cognitive outcomes is unknown. Previous research suggests that timing and dosage of exercise may be important. We synthesized data from clinical and animal studies in order to determine optimal AE training parameters and recovery outcomes for future research. Using predefined criteria, we included clinical trials of stroke of any type or duration and animal studies employing any established models of stroke. Of the 5,259 titles returned, 52 artic...
Source: Neural Plasticity - February 18, 2016 Category: Neurology Authors: Hasan SM, Rancourt SN, Austin MW, Ploughman M Tags: Neural Plast Source Type: research

Modulation of Synaptic Plasticity by Exercise Training as a Basis for Ischemic Stroke Rehabilitation.
Abstract In recent years, rehabilitation of ischemic stroke draws more and more attention in the world, and has been linked to changes of synaptic plasticity. Exercise training improves motor function of ischemia as well as cognition which is associated with formation of learning and memory. The molecular basis of learning and memory might be synaptic plasticity. Research has therefore been conducted in an attempt to relate effects of exercise training to neuroprotection and neurogenesis adjacent to the ischemic injury brain. The present paper reviews the current literature addressing this question and discusses ...
Source: Cellular and Molecular Neurobiology - February 24, 2016 Category: Cytology Authors: Nie J, Yang X Tags: Cell Mol Neurobiol Source Type: research

Predictive analysis for identifying potentially undiagnosed post-stroke spasticity patients in United Kingdom
Conclusions Using machine learning techniques, additional unrecorded post-stroke spasticity patients were identified, increasing the condition’s prevalence in THIN from 2% to 13%. This work shows the potential for under-reporting of PSS in primary care data, and provides a method for improved identification of cases and control records for future studies. Graphical abstract
Source: Journal of Biomedical Informatics - February 29, 2016 Category: Information Technology Source Type: research

Progesterone improves long-term functional and histological outcomes after permanent stroke in older rats.
Abstract Previous studies have shown progesterone to be beneficial in animal models of central nervous system injury, but less is known about its longer-term sustained effects on recovery of function following stroke. We evaluated progesterone's effects on a panel of behavioral tests up to 8 weeks after permanent middle cerebral artery occlusion (pMCAO). Male Sprague-Dawley rats 12m.o. were subjected to pMCAO and, beginning 3h post-pMCAO, given intraperitoneal injections of progesterone (8mg/kg) or vehicle, followed by subcutaneous injections at 8h and then every 24h for 7 days, with tapering of the last 2 treatme...
Source: Behavioural Brain Research - February 24, 2016 Category: Neurology Authors: Wali B, Ishrat T, Stein DG, Sayeed I Tags: Behav Brain Res Source Type: research

The role of auditory feedback in music-supported stroke rehabilitation:A single-blinded randomised controlled intervention.
CONCLUSIONS: Auditory feedback-based motor learning is not the beneficial mechanism of music-supported therapy. Immediate auditory feedback therapy may be suboptimal. Jittered delay may increase efficacy of the proposed therapy and allow patients to fully benefit from motivational factors of music training. Our study shows a novel way to test hypotheses concerning music training in a single-blinded way, which is an important improvement over existing unblinded tests of music interventions. PMID: 26923616 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - March 1, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

A Remote Quantitative Fugl-Meyer Assessment Framework for Stroke Patients Based on Wearable Sensor Networks
To extend the use of wearable sensor networks for stroke patients training and assessment in non-clinical settings, this paper proposes a novel remote quantitative Fugl-Meyer assessment (FMA) framework, in which two accelerometer and seven flex sensors were used to monitoring the movement function of upper limb, wrist and fingers. The extreme learning machine based ensemble regression model was established to map the sensor data to clinical FMA scores while the RRelief algorithm was applied to find the optimal features subset.
Source: Computer Methods and Programs in Biomedicine - March 2, 2016 Category: Bioinformatics Authors: Lei Yu, Daxi Xiong, Liquan Guo, Jiping Wang Source Type: research

Developing a novel peer support intervention to promote resilience after stroke
This study demonstrates the application of the revised UKMRC framework to systematically develop an empirically and theoretically robust intervention to promote resilience after stroke. A future randomised feasibility study is needed to determine whether a full trial is feasible with a larger sample and wider age range of people with stroke.
Source: Health and Social Care in the Community - March 1, 2016 Category: Health Management Authors: Euan Sadler, Sophie Sarre, Anthea Tinker, Ajay Bhalla, Christopher McKevitt Tags: Original Article Source Type: research

Test-retest reliability and convergent validity of three manual dexterity measures in persons with chronic stroke
Conclusion The test-retest reliability of the BBT, NHPT and mSHFT was high but all measures showed learning effects. The relationships between the three measures indicate that they partly complement one another. The BBT may be preferred for persons with moderate impairments of the upper extremity and the NHPT and the mSHFT for persons with milder impairments. As the mSHFT has the advantage of reflecting activities in daily life it may be a suitable alternative to the NHPT.
Source: PMandR - March 11, 2016 Category: Rehabilitation Source Type: research

Rapid learning curve for Solitaire FR stent retriever therapy: evidence from roll-in and randomised patients in the SWIFT trial
Conclusions Thrombectomy in AIS using the Solitaire stent retriever device can be performed safely and effectively when used by experienced neurointerventionalists without previous experience with the device. Trial registration number The SWIFT study is registered with ClinicalTrials.gov, number NCT 01054560.
Source: Journal of NeuroInterventional Surgery - March 15, 2016 Category: Neurosurgery Authors: Sheth, S. A., Jahan, R., Levy, E. I., Jovin, T. G., Baxter, B., Nogueira, R. G., Clark, W., Budzik, R., Zaidat, O. O., Saver, J. L., for the SWIFT Trialists Tags: Ischemic stroke Source Type: research

Reports Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke
Anodal transcranial direct current stimulation (tDCS) can boost the effects of motor training and facilitate plasticity in the healthy human brain. Motor rehabilitation depends on learning and plasticity, and motor learning can occur after stroke. We tested whether brain stimulation using anodal tDCS added to motor training could improve rehabilitation outcomes in patients after stroke. We performed a randomized, controlled trial in 24 patients at least 6 months after a first unilateral stroke not directly involving the primary motor cortex. Patients received either anodal tDCS (n = 11) or sham treatment (n = 13) paired wi...
Source: Science Translational Medicine - March 16, 2016 Category: Biomedical Science Authors: Allman, C., Amadi, U., Winkler, A. M., Wilkins, L., Filippini, N., Kischka, U., Stagg, C. J., Johansen-Berg, H. Tags: Reports Source Type: research

Brain activation is related to smoothness of upper limb movements after stroke.
This study suggests that recruitment of secondary motor areas at 6 weeks after stroke is highly associated with increased jerk during reaching and grasping. As jerk represents the change in acceleration, the recruitment of additional sensorimotor areas seems to reflect a type of control in which deviations from an optimal movement pattern are continuously corrected. This relationship suggests that additional recruitment of sensorimotor areas after stroke may not correspond to restitution of motor function, but more likely to adaptive motor learning strategies to compensate for motor impairments. PMID: 26979435 [PubMe...
Source: Experimental Brain Research - March 15, 2016 Category: Neuroscience Authors: Buma FE, van Kordelaar J, Raemaekers M, van Wegen EE, Ramsey NF, Kwakkel G Tags: Exp Brain Res Source Type: research

Procedural learning as a measure of functional impairment in a mouse model of ischemic stroke.
Abstract Basal ganglia stroke is often associated with functional deficits in patients, including difficulties to learn and execute new motor skills (procedural learning). To measure procedural learning in a murine model of stroke (30min. right MCAO), we submitted C57Bl/6J mice to various sensorimotor tests, then to an operant procedure (Serial Order Learning) specifically assessing the ability to learn a simple motor sequence. Results showed that MCAO affected the performance in some of the sensorimotor tests (accelerated rotating rod and amphetamine rotation test) and the way animals learned a motor sequence. Th...
Source: Behavioural Brain Research - March 17, 2016 Category: Neurology Authors: Linden J, Beeck LV, Plumier JC, Ferrara A Tags: Behav Brain Res Source Type: research

Test−Retest Reliability and Convergent Validity of Three Manual Dexterity Measures in Persons With Chronic Stroke
Conclusion The test−retest reliability of the BBT, NHPT and mSHFT was high but all measures showed learning effects. The relationships between the 3 measures indicate that they partly complement one another. The BBT may be preferred for persons with moderate impairments of the upper extremity and the NHPT and the mSHFT for persons with milder impairments. As the mSHFT has the advantage of reflecting activities in daily life it may be a suitable alternative to the NHPT.
Source: PMandR - March 24, 2016 Category: Rehabilitation Source Type: research

A lesion to learn: Stroke mimics
Publication date: Available online 26 March 2016 Source:Apollo Medicine Author(s): Mahir Meman, Pushpendra Nath Renjen, Dinesh M. Chaudhari Acute ischemic stroke with neurological deficit is a very debilitating condition, especially in younger patients. IV thrombolysis is the only effective treatment available in most of the centers across India. But delay in hospitalization and bleeding complications are major limitations. In addition to that, stroke mimics are another big problem. Correct identification of stroke mimics needs clinical expertise and imaging studies. Multiple studies indicate safety of thrombolysis in...
Source: Apollo Medicine - March 25, 2016 Category: Journals (General) Source Type: research

Computer Imagery and Neurological Rehabilitation: On the Use of Augmented Reality in Sensorimotor Training to Step Up Naturally Occurring Cortical Reorganization in Patients Following Stroke.
Authors: Correa-Agudelo E, Ferrin C, Velez P, Gomez JD Abstract This work promotes the use of computer-generated imagery -as visual illusions- to speed up motor learning in rehabilitation. In support of this, we adhere the principles of experience-dependent neuroplasticity and the positive impact of virtual reality (VR) thereof. Specifically, post-stroke patients will undergo motor therapy with a surrogate virtual limb that fakes the paralyzed limb. Along these lines, their motor intentions will match the visual evidence, which fosters physiological, functional and structural changes over time, for recovery of lost...
Source: Studies in Health Technology and Informatics - April 6, 2016 Category: Information Technology Tags: Stud Health Technol Inform Source Type: research

Kinematic and Kinetic Outcome of Robot Assisted Neurorehabilitation in Chronic Moderate-to-Severe Hemiparetic Stroke (P3.298)
Conclusions: RT+TTT was not significantly different from RT alone, suggesting that TTT did not interfere with motor learning conferred by RT. Study Supported by: American Academy of Neurology (AAN) and the VA Department of Research and Development VA Merit Award B6935RDisclosure: Dr. Iqbal has nothing to disclose. Dr. Conroy has nothing to disclose. Dr. Roy has nothing to disclose. Dr. Bever has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Iqbal, T., Conroy, S., Roy, A., Bever, C. Tags: Neurorehabilitation Source Type: research

Recurrent Alternating Homonymous Hemianopia Due to Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-Like Episodes (MELAS) (P4.260)
CONCLUSIONS: We describe a unique phenomenon of recurrent alternating homonymous hemianopia in MELAS, which should prompt consideration of this diagnosis.Disclosure: Dr. Krysko has nothing to disclose. Dr. Arun has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Krysko, K., Arun, S. Tags: Neuro-ophthalmology/Neuro-otology Source Type: research

Spatial-Motor Flexibility (SMF) and Post-Stroke Cognitive Recovery (P6.014)
Conclusions:The ability to direct movement flexibly in the side of body-centered space near impaired limbs may be needed for optimal functional stroke recovery. The clicker test provides an easy way to assess this ability and its performance may also reflect functioning of executive-action systems. Further studies examining whether SMF deficits predict cognitive recovery in stroke survivors more generally are needed.Disclosure: Dr. Barrett has received personal compensation for activities with Kessler Foundation as an employee. Dr. Barrett has received research support from SPR therapeutics. Dr. Zhang has nothing to disclo...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Barrett, A., Zhang, R., Frey, S., Oh-Park, M. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

Knowledge Translation in Right Brain Rehabilitation: A Feasibility Study of Prism Treatment After Acute Stroke (P6.210)
Conclusions:Fewer patients had spatial neglect than expected, but we demonstrated feasible knowledge translation for spatial neglect care in an underserved setting. An active-learning approach may be key to clinician engagement. Future research in stroke centers will help clarify the impact of neglect assessment and treatment on quality outcomes.Disclosure: Dr. Barrett has received personal compensation for activities with Kessler Foundation as an employee. Dr. Barrett has received research support from SPR therapeutics. Dr. Chen has nothing to disclose. Dr. Hreha has received personal compensation for activities with Kess...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Barrett, A., Chen, P., Hreha, K., Alban, F., Gocon, C., Santos, C., Lawless, K., LaRosa, J. Tags: Behavioral and Cognitive Neurology: Brain-behavior Correlations Source Type: research

High blood pressure: Why me?
“I go to the gym, and I never add salt. So why do I have high blood pressure?” Despite its astonishing prevalence of one in three Americans, many people struggle with the diagnosis of high blood pressure, or hypertension. It’s worth exploring why, because being an active participant in your care is crucial for optimal blood pressure control. Certain features make any diagnosis easier to accept: First, people are more likely to accept a diagnosis if they have symptoms. A person with cough and fever will believe a diagnosis of pneumonia. But someone who feels fine would not. Next, people more readily accept a diagnosi...
Source: New Harvard Health Information - May 2, 2016 Category: Consumer Health News Authors: Naomi D. L. Fisher, MD Tags: Behavioral Health Health care Heart Health Hypertension and Stroke Prevention Screening high blood pressure Source Type: news

Cardiorespiratory fitness and cognitive functioning following short-term interventions in chronic stroke survivors with cognitive impairment: a pilot study
This study, a quasi-experimental, one-group pretest–post-test design, evaluated the effects on cognitive functioning and cardiorespiratory fitness of 8-week interventions (aerobic exercise alone and aerobic exercise and cognitive training combined) in patients with chronic stroke and cognitive impairment living in the community (participants: n=14, 61.93±9.90 years old, 51.50±38.22 months after stroke, n=7 per intervention group). Cognitive functions and cardiorespiratory fitness were evaluated before and after intervention, and at a 3-month follow-up visit (episodic memory: revised-Hopkins Verbal Learning Test; workin...
Source: International Journal of Rehabilitation Research - May 3, 2016 Category: Rehabilitation Tags: Original articles Source Type: research

Alpha-linolenic acid given as enteral or parenteral nutritional intervention against sensorimotor and cognitive deficits in a mouse model of ischemic stroke.
This study evaluated the value of ALA as adjunctive therapy for stroke recovery by comparing whether oral or intravenous supplementation of ALA best support recovery from ischemia. Motor and cognitive deficits were assessed using rotarod, pole and Morris water maze tests. ALA supplementation in diet was better than intravenous treatment in improving motor coordination, but this improvement was not due to a neuroprotective effect since infarct size was not reduced. Both types of ALA supplementation improved spatial learning and memory after stroke. This cognitive improvement correlated with higher survival of hippocampal ne...
Source: Neuropharmacology - April 27, 2016 Category: Drugs & Pharmacology Authors: Bourourou M, Heurteaux C, Blondeau N Tags: Neuropharmacology Source Type: research

Ischemic Stroke
Each year, more than 795,000 people in the United States suffer a stroke and by 2030, it is estimated that 4% of the U.S. population will have had a stroke. Home healthcare clinicians will be increasingly called upon to assist stroke survivors and their caregivers adjust to disability and assist the survivor during their reintegration into the community. Therapeutic modalities are changing with advanced technology. Great strides are being made in the treatment of acute stroke; particularly endovascular interventions. More patients are surviving the acute stroke event and therefore will need to learn how to live with variou...
Source: Home Healthcare Nurse - May 1, 2016 Category: Nursing Tags: Feature Source Type: research

Vascular Risk Factors and Diseases Modulate Deficits of Reward-Based Reversal Learning in Acute Basal Ganglia Stroke
Conclusions The previously reported impairment of reward-based learning may be attributed to vascular risk factors and associated diseases, which are enriched in stroke patients. This study emphasizes the necessity of appropriate control subjects in cognition studies.
Source: PLoS One - May 9, 2016 Category: Biomedical Science Authors: Ulla K. Seidel Source Type: research

Effect of a mixed reality-based intervention on arm, hand, and finger function on chronic stroke
Virtual and mixed reality systems have been suggested to promote motor recovery after stroke. Basing on the existing evidence on motor learning, we have developed a portable and low-cost mixed reality tabletop...
Source: Journal of NeuroEngineering and Rehabilitation - May 11, 2016 Category: Rehabilitation Authors: Carolina Colomer, Roberto Llorens, Enrique Noé and Mariano Alcañiz Source Type: research

I Never Thought Stroke Would Happen to Me
by Myra Wilson, Stroke Survivor On November 3, 2014, I was in nursing school working as a student nurse at a hospital in Seattle. My first sign that something was not quite right was when I was walking through the nursing station and both of my eyes went blurry. I could still see color but I couldn't see letters. It was blurry for about 30 seconds before clearing up again. I was going to lunch and went to give a report to another nurse. The nurse noticed while I was speaking that I slurred my speech. I didn't notice my speech was slurred at all. It was at that time that I experienced a sudden sharp pain on the right s...
Source: Healthy Living - The Huffington Post - May 13, 2016 Category: Consumer Health News Source Type: news

Electroacupuncture ameliorates post-stroke learning and memory through minimizing ultrastructural brain damage and inhibiting the expression of MMP-2 and MMP-9 in cerebral ischemia-reperfusion injured rats.
Authors: Lin R, Yu K, Li X, Tao J, Lin Y, Zhao C, Li C, Chen LD Abstract The aim of the present study was to investigate the potential neuroprotective effects of electroacupuncture (EA) in the treatment of cerebral ischemia/reperfusion (I/R) injury, and to elucidate the association between this neuroprotective effect and brain ultrastructure and expression of matrix metalloproteinase (MMP)‑2 and 9. Rats underwent focal cerebral I/R injury by arterial ligation and received in vivo therapeutic EA at the Baihui (DU20) and Shenting (DU24) acupoints. The therapeutic efficacy was then evaluated following the surgery....
Source: Molecular Medicine Reports - May 15, 2016 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Different stroke(s)
A 13-year-old boy with mild learning difficulties presented to his district general hospital after an unwitnessed episode of collapse with vomiting but no loss of consciousness. He had 3 days of lethargy and intermittent occipital headaches waking him from sleep. Two days later, after another ‘funny turn’, he represented with right-side paraesthesia, weakness and word-finding difficulty. He had three previous ‘collapses’ over the last 6 months, including symptoms of transient dizziness, slurred speech, dribbling, difficulty swallowing and left-facial paraesthesia from which he had recovere...
Source: Archives of Disease in Childhood - Education and Practice - May 17, 2016 Category: Pediatrics Authors: Mundada, V., Krishnakumar, D., Chitre, M., Das, T. Tags: Oncology, Eye Diseases, Drugs: cardiovascular system, Echocardiography, Headache (including migraine), Infection (neurology), Neurooncology, Pain (neurology), Stroke, Hypertension, Ophthalmology, Valvar diseases, Radiology, Rheumatology, Dermatology, Clin Source Type: research

This 18-month-old girl developed left-sided focal seizures, left arm and leg weakness 3 days after an uncomplicated appendicectomy. She had been previously well, and the surgery was uneventful. An urgent cranial MR scan was performed under general anaesthetic within 12 h of the onset of symptoms. Look at the selected images from this study and answer the following questions. Read on to confirm the answers and learn more about the use of diffusion-weighted imaging (DWI) in this condition. Questions There is evidence of acute intracerebral haemorrhage. (True or false?) The abnormality is in the left middle cerebral...
Source: Archives of Disease in Childhood - Education and Practice - May 17, 2016 Category: Pediatrics Authors: Williams, H. Tags: Oncology, Illuminations, Epilepsy and seizures, Stroke, Child health, Other anaesthesia Source Type: research

Combining Dopaminergic Facilitation with Robot-Assisted Upper Limb Therapy in Stroke Survivors: A Focused Review
ABSTRACT: Despite aggressive conventional therapy, lasting hemiplegia persists in a large percentage of stroke survivors. The aim of this article is to critically review the rationale behind targeting multiple sites along the motor learning network by combining robotic therapy with pharmacotherapy and virtual reality–based reward learning to alleviate upper extremity impairment in stroke survivors. Methods for personalizing pharmacologic facilitation to each individual’s unique biology are also reviewed. At the molecular level, treatment with levodopa was shown to induce long-term potentiation-like and practice-depende...
Source: American Journal of Physical Medicine and Rehabilitation - May 21, 2016 Category: Rehabilitation Tags: Literature Review Source Type: research

Neurological Recovery of Upper Extremity in Stroke Woman after 5 Years: A Case Report.
This report describes the case of a stroke patient who gained upper extremity motor recovery after 5 years, which is beyond the normal recovery period. Although the patient does not have functionality, she has partial motor recovery, and she is enthusiastic about learning to gain better use of her hand. However there is still limited evidence to use in designing effective intervention and proper timing of rehabilitation administered by personnel in training chronic stroke patients. Therefore, evidence based on neuroplasticity and neurological recovery in chronic stroke patients, including rehabilitation intervention, is pr...
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - June 10, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

The Zürich Maxi Mental Status Inventory (ZüMAX): Test-Retest Reliability and Discriminant Validity in Stroke Survivors
Conclusion: The ZüMAX has moderate to good test-retest reliability. Furthermore, the tool might discriminate between healthy persons and chronic stroke survivors on three of five subscales. The ZüMAX shows promise in measuring neuropsychological disturbances in stroke survivors; however, further trials are required with larger samples.
Source: Cognitive and Behavioral Neurology - June 1, 2016 Category: Neurology Tags: Original Studies Source Type: research

Upper Extremity Functional Evaluation by Fugl-Meyer Assessment Scoring Using Depth-Sensing Camera in Hemiplegic Stroke Patients
by Won-Seok Kim, Sungmin Cho, Dongyoub Baek, Hyunwoo Bang, Nam-Jong Paik Virtual home-based rehabilitation is an emerging area in stroke rehabilitation. Functional assessment tools are essential to monitor recovery and provide current function-based rehabilitation. We developed the Fugl-Meyer Assessment (FMA) tool using Kinect (Microsoft, USA) and validated it for hemiplegic stroke patients. Forty-one patients with hemiplegic stroke were enrolled. Thirteen of 33 items were selected for upper extremity motor FMA. One occupational therapist assessed the motor FMA while recording upper extremity motion with Kinect. FMA score...
Source: PLoS One - June 30, 2016 Category: Biomedical Science Authors: Won-Seok Kim Source Type: research

For the good of your heart: Keep holding the salt
Your doctor has probably told you to cut back on salt, especially if you have high blood pressure. For years we’ve understood that excess salt raises blood pressure and increases deaths from heart disease. The guilty element is sodium, which pairs with chloride to form common salt. So when the journal Lancet recently published a study reporting that low dietary sodium was associated with an increased risk of heart disease and death, controversy was predictable. A wealth of rigorous scientific studies supports a link between excess sodium intake and high blood pressure, heart attacks, and strokes. Yet the Lancet paper rep...
Source: New Harvard Health Information - July 11, 2016 Category: Consumer Health News Authors: Naomi D. L. Fisher, MD Tags: Healthy Eating Heart Health Hypertension and Stroke Prevention Source Type: news

Stroke Heroes 2016
The American Heart Association/American Stroke Association's Puget Sound Division, along with our sponsor Medtronic, congratulates the honorees for this year's Stroke Hero Awards. We had amazing stories sent to us. Thank you to all of you who submitted a nomination. Here are some of the inspiring individuals honored this year as a Stroke Hero. AMY MOORE, Stroke Survivor Amy is described as a truly an inspiring person who has never let her stroke stop her from accomplishing her goals. Her stroke was diagnosed at six months of age and left her legally blind. Amy learned Braille during her first two years of high school an...
Source: Healthy Living - The Huffington Post - July 12, 2016 Category: Consumer Health News Source Type: news

Crew resource management and simulator training in acute stroke therapy.
CONCLUSION: Even though our data do not allow positive effects on patient outcomes to be inferred, the implementation of a CRM-based stroke team and simulator training has had multiple positive effects on the workflow and work satisfaction in the treatment of acute stroke patients. PMID: 27431675 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - July 17, 2016 Category: Neurology Authors: Tahtali D, Bohmann F, Rostek P, Misselwitz B, Reihs A, Heringer F, Jahnke K, Steinmetz H, Pfeilschifter W Tags: Nervenarzt Source Type: research

Decoding post-stroke motor function from structural brain imaging
Publication date: Available online 2 August 2016 Source:NeuroImage: Clinical Author(s): Jane M. Rondina, Maurizio Filippone, Mark Girolami, Nick S. Ward Clinical research based on neuroimaging data has benefited from machine learning methods, which have the ability to provide individualized predictions and to account for the interaction among units of information in the brain. Application of machine learning in structural imaging to investigate diseases that involve brain injury presents an additional challenge, especially in conditions like stroke, due to the high variability across patients regarding characteristics of ...
Source: NeuroImage: Clinical - August 2, 2016 Category: Radiology Source Type: research

Quality Improvement in Acute Ischemic Stroke Care in Taiwan: The Breakthrough Collaborative in Stroke
by Fang-I Hsieh, Jiann-Shing Jeng, Chang-Ming Chern, Tsong-Hai Lee, Sung-Chun Tang, Li-Kai Tsai, Hsun-Hsiang Liao, Hang Chang, Kenneth A. LaBresh, Hung-Jung Lin, Hung-Yi Chiou, Hou-Chang Chiu, Li-Ming Lien, for the BTS-Stroke Investigators In the management of acute ischemic stroke, guideline adherence is often suboptimal, particularly for intravenous thrombolysis or anticoagulation for atrial fibrillation. We sought to improve stroke care quality via a collaborative model, the Breakthrough Series (BTS)-Stroke activity, in a nationw ide, multi-center activity in Taiwan. A BTS Collaborative, a short-term learning system fo...
Source: PLoS One - August 2, 2016 Category: Biomedical Science Authors: Fang-I Hsieh Source Type: research