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Anaesthetic management of transcatheter aortic valve implantation: results from the Italian CoreValve registry.
CONCLUSIONS: Our study indicates that, in experienced centres which have gone beyond their initial learning curve with TAVI, the use of local anaesthesia in a selected patient population can be associated with good clinical outcomes. Nevertheless, as severe procedural complications are possible, an anaesthesiologist should always be present as part of the team. PMID: 25772903 [PubMed - as supplied by publisher]
Source: EuroIntervention - March 20, 2015 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

The Most Promising Cancer-Fighter In Years
For a while now, I’ve been recommending a powerful antioxidant with the unpronounceable name, pyrroloquinoline quinine – or PQQ for short. And although I recommend this compound to almost everyone who comes to see me at my wellness clinic in South Florida because of its energy-giving qualities, I’ve also observed its extraordinary power to fight cancer. For years, I’ve seen PQQ work wonders with my older patients, because it keeps you feeling young by giving your cells extra energy. PQQ was first discovered back in 1979 by a team of Japanese scientists, who knew little about the substance, except that i...
Source: Al Sears, MD Natural Remedies - March 24, 2015 Category: Complementary Medicine Authors: Andrew Britton Tags: Anti-Aging antioxidants Cancer energy Source Type: news

Contrast-enhanced ultrasound to predict the risk of microembolization during carotid artery stenting
Conclusion Contrast enhancement of the carotid plaque is strongly associated with post-procedural microembolization and for this reason it can be considered a reliable tool for an accurate selection of patients undergoing this endovascular treatment. However, the neurocognitive test scores performed in this study are not enough sensible to appreciate the impact of the neurological injury on the day life activities.
Source: La Radiologia Medica - March 25, 2015 Category: Radiology Source Type: research

Invited Commentary on Comparison of Robotics, Functional Electrical Stimulation, and Motor Learning Methods for Treatment of Persistent Upper Extremity Dysfunction After Stroke: A Randomized Controlled Trial
In this issue of Archives of Physical Medicine and Rehabilitation, Jessica McCabe and colleagues report findings from their methodologically sound, dose-matched clinical trial in 39 patients beyond 6 months poststroke. In this phase II trial, the effects of 60 treatment sessions, each involving 3.5 hours of intensive practice plus either 1.5 hours of functional electrical stimulation (FES) or a shoulder-arm robotic therapy, were compared with 5 hours of intensive daily practice alone. Although no significant between-group differences were found on the primary outcome measure of Arm Motor Ability Test and the secondary outc...
Source: Archives of Physical Medicine and Rehabilitation - February 13, 2015 Category: Rehabilitation Authors: Gert Kwakkel, Erwin E. van Wegen, Carel M. Meskers Tags: INVITED Commentary Source Type: research

Precision medicine is coming, but not anytime soon
President Obama’s announcement of a Precision Medicine Initiative was one of the few items in this year’s State of the Union address to garner bipartisan support. And for good reason. Precision medicine, also known as personalized medicine, offers the promise of health care — from prevention to diagnosis to treatment — based on your unique DNA profile. Who wouldn’t want that? We’ve already had a taste of precision medicine. Relatively low-tech therapies like eyeglasses, orthotic devices, allergy treatments, and blood transfusions have long been personalized for the individual. Genetic analysis o...
Source: New Harvard Health Information - March 26, 2015 Category: Consumer Health News Authors: Beverly Merz Tags: Health care personalized health care precision medicine Source Type: news

Positive effects of the traditional Chinese medicine MLC901 in cognitive tasks
MLC901 (NurAiDII) is used as a treatment for stroke patients. It has been shown that MLC901 improves motor and cognitive recovery in ischemic and traumatic brain‐injured rodents. The present study seeks to delineate cognitive effects induced by MLC901 in normal, noninjured mice. To this end, the behaviors of vehicle‐ and MLC901‐treated C57BL/6 mice in hippocampus‐dependent (passive avoidance, Morris water maze) and hippocampus‐independent (novel object recognition) cognitive tasks are compared. The potential influence of the compound on the anxiety level and nycthemeral rhythm of mice is also assessed. In additio...
Source: Journal of Neuroscience Research - March 29, 2015 Category: Neuroscience Authors: T. Lorivel, C. Gandin, J. Veyssière, M. Lazdunski, C. Heurteaux Tags: Research Article Source Type: research

Blood pressure measurement in pregnancy
Key content Accurate blood pressure (BP) measurement is fundamental to early diagnosis of hypertensive disorders in pregnancy. Poor auscultatory technique and lack of training leads to inaccuracies in BP measurement using sphygmomanometry with mercury and aneroid devices. Automated devices limit user error but require validation of accuracy because they tend to underestimate BP in pre‐eclampsia. Systolic hypertension may better predict risk of adverse outcome (such as haemorrhagic stroke) than diastolic hypertension. Ambulatory/self‐monitoring increases the number of representative readings available on which to ...
Source: The Obstetrician and Gynaecologist - April 1, 2015 Category: OBGYN Authors: Hannah L Nathan, Kate Duhig, Natasha L Hezelgrave, Lucy C Chappell, Andrew H Shennan Tags: Review Source Type: research

Artificial sweeteners are not the answer to childhood obesity.
Abstract While no single factor is responsible for the recent, dramatic increases in overweight and obesity, a scientific consensus has emerged suggesting that consumption of sugar-sweetened products, especially beverages, is casually linked to increases in risk of chronic, debilitating diseases including type 2 diabetes, cardiovascular disease, hypertension and stroke. One approach that might be beneficial would be to replace sugar-sweetened items with products manufactured with artificial sweeteners that provide sweet tastes but with fewer calories. Unfortunately, evidence now indicates that artificial sweetener...
Source: Appetite - March 27, 2015 Category: Nutrition Authors: Swithers SE Tags: Appetite Source Type: research

Idaho mom goes the distance to help teen with scoliosis
“You want a hospital with the best technology and the best nurses and doctors in the country. You expect that, and you expect it to be clean. Boston Children’s has all of that,” says Lisa Findlay, a mom from Hayden, Idaho. “What made the difference was how much everyone loves these kids. Everyone who walked into Aaron’s room, from the surgeons to nurses’ aides to janitors and child life specialists, was on a mission to help Aaron.” From the time he was born, Aaron encountered one medical challenge after another. He was born with hypoplastic left heart syndrome (HLHS), a serious congenital heart defect. By...
Source: Thrive, Children's Hospital Boston - April 2, 2015 Category: Pediatrics Authors: Lisa Fratt Tags: Orthopedics Our patients’ stories Source Type: news

HyDRA: gene prioritization via hybrid distance-score rank aggregation
Summary: Gene prioritization refers to a family of computational techniques for inferring disease genes through a set of training genes and carefully chosen similarity criteria. Test genes are scored based on their average similarity to the training set, and the rankings of genes under various similarity criteria are aggregated via statistical methods. The contributions of our work are threefold: (i) first, based on the realization that there is no unique way to define an optimal aggregate for rankings, we investigate the predictive quality of a number of new aggregation methods and known fusion techniques from machine lea...
Source: Bioinformatics - April 2, 2015 Category: Bioinformatics Authors: Kim, M., Farnoud, F., Milenkovic, O. Tags: SYSTEMS BIOLOGY Source Type: research

Individuals Poststroke Do Not Perceive Their Spatiotemporal Gait Asymmetries as Abnormal.
CONCLUSIONS: These data suggest that asymmetry magnitudes need to exceed usual overground levels to reach conscious awareness. Therefore, we propose that the spatiotemporal asymmetry that is specific to each subject may need to be augmented beyond what they usually walk with in order to promote awareness of asymmetric gait patterns for long-term correction and learning. PMID: 25838335 [PubMed - as supplied by publisher]
Source: Physical Therapy - April 2, 2015 Category: Physiotherapy Authors: Wutzke CJ, Faldowski RA, Lewek MD Tags: Phys Ther Source Type: research

Sleep duration is associated with worse neurocognitive function in Hispanic/Latinos: Results of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (I9-4A)
CONCLUSIONS: Sleep duration had an inverted J-shaped curvilinear association with neurocognitive function, such that those with longer sleep duration had worse neurocognitive scores. Study Supported by: The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Cent...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ramos, A., Tarraf, W., Daviglus, M., Davis, S., Gallo, L., Mossavar-Rahmani, Y., Penedo, F., Redline, S., Rundek, T., Sacco, R., Sotres-Alvarez, D., Wright, C., Zee, P., Gonzalez, H. Tags: Treating Dementia in an Age of Mixed Disease Data Blitz Presentations Source Type: research

Sleep duration is associated with worse neurocognitive function in Hispanic/Latinos: Results of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (P1.100)
CONCLUSIONS: Sleep duration had an inverted J-shaped curvilinear association with neurocognitive function, such that those with longer sleep duration had worse neurocognitive scores. Study Supported by: The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Cent...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ramos, A., Tarraf, W., Daviglus, M., Davis, S., Gallo, L., Mossavar-Rahmani, Y., Penedo, F., Redline, S., Rundek, T., Sacco, R., Sotres-Alvarez, D., Wright, C., Zee, P., Gonzalez, H. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

A comprehensive simulation curriculum for neurology residents - preparing for future challenges in neurology (P4.188)
CONCLUSIONS: Our study demonstrates that integrating simulation in classical neurology didactics not only improves the knowledge base but improves competency and execution of high-risk time sensitive decisions in an emergency setting.Disclosure: Dr. Sabharwal has nothing to disclose. Dr. Saba has nothing to disclose. Dr. Szyld has nothing to disclose. Dr. Czeisler has nothing to disclose. Dr. Ishida has nothing to disclose. Dr. Lord has nothing to disclose. Dr. Rucker has nothing to disclose. Dr Balcer received personal compensation from Biogen Idec and consulting for Biogen Idec, Vaccinex and Genzyme. She is on a clinical...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Sabharwal, P., Saba, S., Szyld, D., Czeisler, B., Ishida, K., Lord, A., Rucker, J., Balcer, L., Sander, H., Galetta, S. Tags: Research Methodology and Education Source Type: research

Individualized neuro-cognitive rehabilitation can reverse cognitive and memory impairment irrespective of etiology: Prospective pilot study (P6.189)
Conclusion: Supervised neurocognitive rehabilitation, specifically designed for individual provides significant reversal of cognitive deficit in adult patients with cognitive impairment, regardless of the etiology.Disclosure: Dr. Kumar has nothing to disclose. Dr. Kumar has nothing to disclose. Dr. Jawahar has nothing to disclose. Dr. Kumar has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kumar, S., Kumar, J., Jawahar, A., Kumar, M. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology: Dementia: Psychosocial Aspects Source Type: research

Regular aspirin use does not reduce risk of incident cognitive decline (P7.117)
CONCLUSIONS: Regular aspirin did not provide a protective association against incident cognitive impairment in a large, biracial, and geographically diverse cohort. Study Supported by: This research project is supported by a cooperative agreement U01 NS041588 from the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Service. Disclosure: Dr. Kelley has received personal compensation for activities with Eli Lilly & Co. as a consultant. Dr. McClure has received research support from Genzyme and Amgen. Dr. Unverzagt has received personal compensation...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Kelley, B., McClure, L., Unverzagt, F., Kissela, B., Kleindorfer, D., Howard, G., Wadley, V. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology: Cardio- and Cerebrovascular Factors in Dementia Source Type: research

Promoting Locomotor Learning with Spinal Direct Current Stimulation- Pilot Data (S28.005)
CONCLUSION: After interim analysis, we repowered the study and determined that 14 additional healthy volunteers per group will be needed, to achieve a statistical significance of 97.5 percent and a power of 0.80. Results gathered at this stage will allow us to further assess the effect of tDCS at different stages of locomotor learning, including online, offline, and total learning-- necessary for application in future neurorehabilitation trials involving patients with spinal cord injury and stroke. Study Supported by: Intramural Research Program, NINDSDisclosure: Dr. Awosika has nothing to disclose. Dr. Sandrini has nothin...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Awosika, O., Sandrini, M., Volochayev, R., Xu, B., Floeter, M. K., Hallett, M., Cohen, L. Tags: Neuro-rehabilitation Source Type: research

No such thing as baby brain, study argues
Conclusion The researchers conclude that although the pregnant women reported memory problems, these did not show up on their tests. However, this does not take into account their pre-pregnancy ability. The women may have performed better before they got pregnant, which is why they are now reporting memory problems. None of these women were tested before they got pregnant, which is the major limitation of the study. The researchers say that because there were a similar number of students in each group, the women in the control group was a good enough representation of how the pregnant women would have performed pre-pregna...
Source: NHS News Feed - April 8, 2015 Category: Consumer Health News Tags: Mental health Neurology Pregnancy/child Source Type: news

Complex assessment of distinct cognitive impairments following ouabain injection into the rat dorsoloateral striatum.
In conclusion, we developed an animal model of distinct cognitive impairments after focal brain injury that provides a convenient method to test the effectiveness of restorative therapies. PMID: 25845737 [PubMed - as supplied by publisher]
Source: Behavioural Brain Research - April 3, 2015 Category: Neurology Authors: Gornicka-Pawlak E, Janowski M, Jablonska A, Sypecka J, Domanska-Janik K Tags: Behav Brain Res Source Type: research

Neuromechanical Principles Underlying Movement Modularity and Their Implications for Rehabilitation
Publication date: 8 April 2015 Source:Neuron, Volume 86, Issue 1 Author(s): Lena H. Ting , Hillel J. Chiel , Randy D. Trumbower , Jessica L. Allen , J. Lucas McKay , Madeleine E. Hackney , Trisha M. Kesar Neuromechanical principles define the properties and problems that shape neural solutions for movement. Although the theoretical and experimental evidence is debated, we present arguments for consistent structures in motor patterns, i.e., motor modules, that are neuromechanical solutions for movement particular to an individual and shaped by evolutionary, developmental, and learning processes. As a consequence, ...
Source: Neuron - April 10, 2015 Category: Neuroscience Source Type: research

The effects of sigma (σ1) receptor‐selective ligands on muscarinic receptor antagonist‐induced cognitive deficits in mice
Conclusions and ImplicationsThe σ1 receptor‐selective compound LS‐1–137 may represent a novel candidate cognitive enhancer for the treatment of muscarinic receptor‐dependent cognitive deficits.
Source: British Journal of Pharmacology - April 10, 2015 Category: Drugs & Pharmacology Authors: Maninder Malik, Claudia Rangel‐Barajas, Nathalie Sumien, Chang Su, Meharvan Singh, Zhenglan Chen, Ren‐Qi Huang, Johann Meunier, Tangui Maurice, Robert H Mach, Robert R Luedtke Tags: RESEARCH PAPER Source Type: research

Perspective of synaptic protection after post-infarction treatment with statins
Stroke is the second most common cause of death in people over 45 years of age in Colombia and is the leading cause of permanent disability worldwide. Cerebral ischemia is a stroke characterized by decreased blood flow due to the occlusion of one or more cerebral arteries, which can cause memory problems and hemiplegia or paralysis, among other impairments. The literature contains hundreds of therapies (invasive and noninvasive) that exhibit a neuroprotective effect when evaluated in animal models. However, in clinical trials, most of these drugs do not reproduce the previously demonstrated neuroprotective property, and s...
Source: BioMed Central - April 13, 2015 Category: Journals (General) Authors: Johanna Gutiérrez-VargasAngel Cespedes-RubioGloria Cardona-Gómez Source Type: research

Action observation with kinesthetic illusion can produce human motor plasticity
This article is protected by copyright. All rights reserved.
Source: European Journal of Neuroscience - April 17, 2015 Category: Neuroscience Authors: Ippei Nojima, Satoko Koganemaru, Toshio Kawamata, Hidenao Fukuyama, Tatsuya Mima Tags: Research Report Source Type: research

The protective effect of caffeic acid on global cerebral ischemia-reperfusion injury in rats
Ischemic stroke is a major cause of death and disability all over the world. Ischemic stroke results from a temporary or permanent reduction of cerebral blood flow that leads to functional and structural damage in different brain regions. Despite decades of intense research, the beneficial treatment of stroke remains limited. In light of this, the search for effective means ameliorating cerebral ischemia-reperfusion injury (CIRI) is one of the major problems of experimental medicine and biology. Recently, the 5-Lipoxygenase (5-LO, a key enzyme metabolizing arachidonic acid to produce leukotrienes) inhibitors have been show...
Source: Behavioral and Brain Functions - April 18, 2015 Category: Neurology Authors: Guojuan LiangBin ShiWeinan LuoJunqing Yang Source Type: research

3 Key Nutrients For Better Brainpower
By Nancy Christie When it comes to what we eat, we usually worry more about our waistlines than our wisdom. But a diet that contains a wide assortment of healthy foods and nutrients doesn’t just benefit your body; it may protect your brain from cognitive decline as you age. In order to defend against a variety of age-related conditions that can impair your memory and the general functioning of your brain, a good first step is to concentrate on incorporating three nutrients into your diet: omega-3 fatty acids, flavonoids and vitamin E. 1. Omega-3 Fatty Acids for Brain Volume For your memory to function smoothly, your br...
Source: Healthy Living - The Huffington Post - April 26, 2015 Category: Consumer Health News Source Type: news

Work Wellness Programs May Soon Include Genetic Testing
Your employer may one day help determine if your genes are why your jeans have become too snug. Big companies are considering blending genetic testing with coaching on nutrition and exercise to help workers lose weight and improve their health before serious conditions like diabetes or heart disease develop. It's a step beyond the typical corporate wellness programs that many companies are using to make workers more aware of their risk factors and improve their health. Genetic testing in corporate wellness programs also is relatively uncharted territory. Many employers and insurers cover these tests and counseling for med...
Source: Science - The Huffington Post - April 29, 2015 Category: Science Source Type: news

Rethinking Retirement in the 21st Century
Conclusion In the 21st century, many seniors are not retiring from something. Instead, retirement is an opportunity for reinventing, reimagining and reconnecting to one's self, family, friends and community. Robert Browning once wrote, "Grow old along with me! The best is yet to be." By investing in your physical, mental and financial health today, you can help ensure that your best years are just ahead. Rear Admiral Susan Blumenthal, M.D., M.P.A. (ret.) is the Public Health Editor of The Huffington Post. She is a Senior Fellow in Health Policy at New America and a Clinical Professor at Tufts and Georgetown University Sc...
Source: Healthy Living - The Huffington Post - May 1, 2015 Category: Consumer Health News Source Type: news

Hyperbaric oxygen therapy fails to reduce hydrocephalus formation following subarachnoid hemorrhage in rats
Conclusion Multiple HBO therapy does not ameliorate hydrocephalus formation in a rat model of SAH; however, HBO tendentially improved the neurological functions and spatial learning and memory abilities in rats with hydrocephalus.
Source: Medical Gas Research - July 9, 2014 Category: Biomedical Science Source Type: research

New Insights from Major Prospective Cohort Studies with Cardiovascular Magnetic Resonance (CMR)
Abstract Since 1948, epidemiology studies played an important role in understanding cardiovascular disease and afforded an opportunity to learn about newer diagnostic tests. In 2000, the MESA Study incorporated several advanced cardiovascular imaging modalities including cardiac magnetic resonance imaging (MRI) and coronary artery calcium scans. The decade of follow-up enabled prognosis studies, an important step beyond association studies. In brief, left ventricular hypertrophy by cardiac MRI predicted incident heart failure and stroke. In the MESA Study, coronary artery calcium was a better predictor of coronar...
Source: Current Cardiology Reports - May 5, 2015 Category: Cardiology Source Type: research

Act F.A.S.T. and Save a Life!
Yes, I'm getting older! My knees hurt for no reason at times and my joints pop and crack like an old house settling. Yet I continue to push through by working out regularly, eating healthy, and hoping to slow down Father Time and ignore my athletic mortality. Many of my physician colleagues admit to neglecting their health due to the busy lives they lead, but I try my best to practice what I preach. Stressing the importance of healthy eating, being physically active, taking medication as prescribed and regular follow ups with a physician is more than just a reflex recommendation to my patients. It is an integral part of my...
Source: Healthy Living - The Huffington Post - May 7, 2015 Category: Consumer Health News Source Type: news

Evaluating the User Experience of Exercising Reaching Motions With a Robot That Predicts Desired Movement Difficulty.
This study demonstrates the efficiency of delivering the exercises at the user's desired difficulty level to improve the user's engagement in exercise tasks. Future work will focus on clinical feasibility of this approach in increasing stroke survivors' engagement in their therapy programs. PMID: 25945816 [PubMed - as supplied by publisher]
Source: Journal of Motor Behavior - May 8, 2015 Category: Neurology Tags: J Mot Behav Source Type: research

Gear: The latest for stand-up paddle board fans on the go
The stand-up paddle board, or SUP, is one of the hottest sports products right now. People of all abilities love the comfortable standing position, the smooth and easy-to-learn paddle stroke, the upper-body and core workout, and the excuse to get out in the sunshine and onto the water. What they...
Source: L.A. Times - Health - May 8, 2015 Category: Consumer Health News Source Type: news

Preliminary Evidence of Disparities in Physical Activity among Adolescents with Bipolar Disorder
Conclusions Frontal-executive dysfunction implicates frontal brain regions, which are known to be susceptible to oxidative damage. Further studies are needed, and those examining psychiatric populations may be especially fruitful. Focusing on youth may yield enhanced signal detection. Further study is needed to identify which antioxidant interventions work best for which cognitive functions and for which patients.
Source: Mental Health and Physical Activity - May 10, 2015 Category: Psychiatry & Psychology Source Type: research

Things I Wish I'd Known When I Was Younger
I am 64 years old. There, I admit it. Women don't always want to admit their age, but there is one really good thing about seeing the decades roll by: I finally appreciate that "women's health" means different things at different times. For this year's National Women's Health Week, we're focusing on what steps women can take at different ages and stages to live a healthier life. And now that I am older, I'd like to share some of my thoughts on things I wish someone had told me when I was younger. In my 20s Fall in love with working out. Sometimes when you're young, you think you don't need to exercise. You can run, jum...
Source: Healthy Living - The Huffington Post - May 11, 2015 Category: Consumer Health News Source Type: news

The neural correlates of road sign knowledge and route learning in semantic dementia and Alzheimer's disease
Discussion and conclusions For the first time, driving skills were explored in SD, and it is showed a differential profile from the one detected in AD. We demonstrate that the left anterior temporal cortex is implicated in road sign knowledge, while a distributed cortical network, including the frontal cortex, is likely to process route learning.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 14, 2015 Category: Neurosurgery Authors: Luzzi, S., Cafazzo, V., Damora, A., Fabi, K., Fringuelli, F. M., Ascoli, G., Silvestrini, M., Provinciali, L., Reverberi, C. Tags: Dementia, Drugs: CNS (not psychiatric), Stroke, Memory disorders (psychiatry), Psychiatry of old age, Radiology, Radiology (diagnostics) Cognitive neurology Source Type: research

Neuropsychological changes following deep brain stimulation surgery for Parkinson's disease: comparisons of treatment at pallidal and subthalamic targets versus best medical therapy
Conclusions In those with PD, the likelihood of significant decline in neuropsychological functioning increases with DBS, affecting a small minority of patients who also appear to respond less optimally to DBS by other indicators of QOL. Trial registration number NCT00056563 and NCT01076452.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 14, 2015 Category: Neurosurgery Authors: Rothlind, J. C., York, M. K., Carlson, K., Luo, P., Marks, W. J., Weaver, F. M., Stern, M., Follett, K., Reda, D., Ippolito, Stoner, Barnett, Bukowski, DeNicolo, Hur, Jimenez, Motyka, Simon, Thakkar, Woolson, Fye, Gagne, Harris, Heemskerk, Moy, Sheehy, O' Tags: Drugs: CNS (not psychiatric), Parkinson's disease, Stroke, Memory disorders (psychiatry) Multiple sclerosis Source Type: research

The Great Pot Experiment
Barcott is a journalist who has contributed to the New York Times, National Geographic and other publications. Scherer is TIME’s Washington bureau chief. Portions of this article were adapted from Barcott’s new book “Weed the People, the Future of Legal Marijuana in America,” from TIME Books, is now available wherever books are sold, including Amazon.com, Barnes & Noble and Indiebound. Yasmin Hurd raises rats on the Upper East Side of Manhattan that will blow your mind. Though they look normal, their lives are anything but, and not just because of the pricey real estate they call home on the 10t...
Source: TIME.com: Top Science and Health Stories - May 14, 2015 Category: Consumer Health News Authors: Megan Gibson Tags: Uncategorized Drugs Source Type: news

Parietal lesion Effects on cued recall following pair associate learning
Publication date: Available online 18 May 2015 Source:Neuropsychologia Author(s): Shir Ben-Zvi , Nachum Soroker , Daniel A. Levy We investigated the involvement of the posterior parietal cortex in episodic memory in a lesion-effects study of cued recall following pair-associate learning. Groups of patients who had experienced first-incident stroke, generally in middle cerebral artery territory, and exhibited damage that included lateral posterior parietal regions, were tested within an early post-stroke time window. In three experiments, patients and matched healthy comparison groups executed repeated study and cued reca...
Source: Neuropsychologia - May 20, 2015 Category: Neurology Source Type: research

John Glenn Says Evolution Should Be Taught In Schools
COLUMBUS, Ohio (AP) — John Glenn, who declared as a 77-year-old in a news conference from space that "to look out at this kind of creation out here and not believe in God is to me impossible," says facts about scientific discovery should be taught in schools — and that includes evolution. The astronaut, now 93 with fading eyesight and hearing, told The Associated Press in a recent interview that he sees no contradiction between believing in God and believing in evolution. "I don't see that I'm any less religious by the fact that I can appreciate the fact that science just records that we change with evolution and tim...
Source: Science - The Huffington Post - May 20, 2015 Category: Science Source Type: news

The 8 Most Important Things We've Learned About Happiness In The Past 10 Years
We're living in a golden age of happiness -- the scientific study of happiness, at least. The field of positive psychology has exploded in growth since its inception in 1998, dramatically increasing our understanding of human flourishing. We now know more than ever about what makes us happy, how we can spread happiness socially and geographically, and how happiness affects our physical and mental health. But it's just the beginning. In the next decade, we're likely to see not only a greater understanding of positive emotions, but also the application of this research on a practical level to improve well-being on a globa...
Source: Science - The Huffington Post - May 23, 2015 Category: Science Source Type: news

What Are Common Inherited Thrombophilias?
Discussion Thrombophilia is the increased risk of thromboembolic disease due to a disorder. Thrombophilia can be inherited or acquired (such as antiphospholipid syndrome). The risk of thromboembolic events is much lower in children than adults. At-risk patients should avoid: Dehydration Sitting for prolonged time periods during travel Obesity Smoking Estrogen containing oral contraceptives Common inherited thrombophilias include: Prothrombin (Factor II mutation) Second most common Genetics: 1-2% prevalence is variable depending on location and ethnic background. Cause: Abnormal point mutation of the prothrombin gene t...
Source: PediatricEducation.org - May 25, 2015 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

A Hidden Danger In The New Versions Of Birth Control Pills
Women who take a newer version of birth control pills have a doubled risk of developing potentially fatal blood clots, according to a new study published in the British medical journal BMJ. Venous thromboembolism is a serious condition that encompasses both deep vein thrombosis -- when a person develops a blood clot in the legs -- and pulmonary embolism, in which the clot travels to the lungs and obstructs breathing. VTE is potentially fatal, and the study indicates that women who take combined oral contraceptives with newer progesterone formulations are two times more likely to develop it as opposed to women who take a ...
Source: Science - The Huffington Post - May 27, 2015 Category: Science Source Type: news

Inflammatory Claims About Inflammation
We all appreciate the elegance of simple solutions to complex problems. But we know too that simplicity can often masquerade as truth, hiding a more nuanced reality. Such is the case with inflammation, where pseudoscience, exaggerated claims, false promises, and dangerous oversimplification have dominated for too long. Here is a typical missive: "Inflammation controls our lives. Have you or a loved one dealt with pain, obesity, ADD/ADHD, peripheral neuropathy, diabetes, heart disease, stroke, migraines, thyroid issues, dental issues, or cancer? If you answered yes to any of these disorders you are dealing with inflammatio...
Source: Science - The Huffington Post - May 29, 2015 Category: Science Source Type: news

Editors' Selections From This Issue: Volume 96 / Number 6 / June 2015
In this month's podcast, we interview Janis J. Daly, PhD, MS, on the featured article Comparison of Robotics, Functional Electrical Stimulation, and Motor Learning Methods for Treatment of Persistent Upper Extremity Dysfunction After Stroke: A Randomized Controlled Trial by McCabe et al. (See the full article at page 981.) This podcast, and our full collection of author podcasts, is available at http://www.archives-pmr.org/content/podcast_collection.
Source: Archives of Physical Medicine and Rehabilitation - May 30, 2015 Category: Rehabilitation Source Type: research

Hacking The Nervous System
(Photo: © Job Boot) One nerve connects your vital organs, sensing and shaping your health. If we learn to control it, the future of medicine will be electric.When Maria Vrind, a former gymnast from Volendam in the Netherlands, found that the only way she could put her socks on in the morning was to lie on her back with her feet in the air, she had to accept that things had reached a crisis point. “I had become so stiff I couldn’t stand up,” she says. “It was a great shock because I’m such an active person.”It was 1993. Vrind was in her late 40s and working two jobs, athletics coach and a carer for disabled ...
Source: Science - The Huffington Post - May 30, 2015 Category: Science Source Type: news

Is Aortic Valve Repair Reproducible? Analysis of the Learning Curve for Aortic Valve Repair
Conclusions Procedural safety and efficiency improves with experience whereas efficacy is consistent over time. AV repair is reproducible and appears to have a learning curve of approximately 40-60 cases. Teaser Aortic valve repair, while effective, is performed in a limited number of centres. We examined the learning curve in two centres with programs in AV repair for safety, efficiency, and efficacy endpoints. Early mortality was ≤1% in both cohorts. Frequency of safety endpoints was reduced in both cohorts. Procedural safety and efficiency improved with experience whereas efficacy was consistent over time. AV repair i...
Source: Canadian Journal of Cardiology - June 1, 2015 Category: Cardiology Source Type: research

Has Brazil found the way to better health care?
Under Brazil’s family health program, when a woman learns that she is pregnant, she contacts her local community health agent, who often is a neighbor. Typically, the agent visits her home to arrange an appointment with the neighborhood’s family health team, and the woman visits the health center for an assessment by a nurse assistant and a physician. During the pregnancy, if she misses a prenatal care appointment, the agent checks in on her at home and helps her reschedule her visit. Any prenatal medications she needs are provided free of charge. Brazil — home to the world’s fifth-largest population and seventh-l...
Source: UCLA Newsroom: Health Sciences - June 5, 2015 Category: Universities & Medical Training Source Type: news

Observing the Damaged Brain for Clues About Dreaming
Thanks to advanced and digital technologies, a close study of the dreaming brain is possible. Dream researchers use neural-imaging tools range from EEG to PET scan to MRI to observe the brain's activity while dreaming. In addition to observing healthy brain activity, scientists also use cases of brain injury and illness as a way to learn about the brain mechanics of dreaming. This approach -- of learning about the functions of the brain through abnormalities, injury, or illness -- is by no means just confined to the study of dreams. A great deal of what we know about the mechanics of the brain in general has come from ob...
Source: Healthy Living - The Huffington Post - June 6, 2015 Category: Consumer Health News Source Type: news