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Total 1715 results found since Jan 2013.

Quantitative Assessment of Upper-Limb Motor Function for Post-Stroke Rehabilitation Based on Motor Synergy Analysis and Multi-Modality Fusion
Functional assessment is an essential part of rehabilitation protocols after stroke. Conventionally, the assessment process relies heavily on clinical experience and lacks quantitative analysis. In order to objectively quantify the upper-limb motor impairments in patients with post-stroke hemiparesis, this study proposes a novel assessment approach based on motor synergy quantification and multi-modality fusion. Fifteen post-stroke hemiparetic patients and fifteen age-matched healthy persons participated in this study. During different goal-directed tasks, kinematic data and surface electromyography(sEMG) signals were sync...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 31, 2020 Category: Neuroscience Source Type: research

Machine learning volumetry of ischemic brain lesions on CT after thrombectomy —prospective diagnostic accuracy study in ischemic stroke patients
ConclusionNCCT ILV measured automatically by the Brainomix software might be considered a valuable radiological outcome measure.
Source: Neuroradiology - April 21, 2020 Category: Radiology Source Type: research

p5 Peptide-Loaded Human Adipose-Derived Mesenchymal Stem Cells Promote Neurological Recovery After Focal Cerebral Ischemia in a Rat Model
In conclusion, administration of hADMSC-loaded p5 peptide to post-stroke rats created conditions that supported survival of drug-loaded hADMSCs after cerebral ischemia, suggesting its therapeutic potential in patients with stroke.
Source: Translational Stroke Research - May 5, 2020 Category: Neurology Source Type: research

Coagulopathy signature precedes and predicts severity of end-organ heat stroke pathology in a mouse model.
CONCLUSIONS: Heat stroke-induced coagulopathy may be a driving mechanistic force in heat stroke pathology, especially when exacerbated by prior infection. Coagulation markers may serve as accessible biomarkers for heat stroke severity and therapeutic strategies. PMID: 32367690 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - May 3, 2020 Category: Hematology Authors: Proctor EA, Dineen SM, Van Nostrand SC, Kuhn MK, Barrett CD, Brubaker DK, Yaffe MB, Lauffenburger DA, Leon LR Tags: J Thromb Haemost Source Type: research

Integration of ultra-high-pressure liquid chromatography-tandem mass spectrometry with machine learning for identifying fatty acid metabolite biomarkers of ischemic stroke
We report for the first time the integration of ultra-high-pressure liquid chromatography-tandem mass spectrometry with machine learning for identifying fatty acid metabolite biomarkers of ischemic stroke. Especially, we develop an... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - May 8, 2020 Category: Chemistry Authors: Lijian Zhang Source Type: research

Treatment Effects of Upper Limb Action Observation Therapy and Mirror Therapy on Rehabilitation Outcomes after Subacute Stroke: A Pilot Study.
Conclusion: The preliminary results found that the patients in the action observation therapy and active control intervention groups had comparable benefits, suggesting that the 2 treatments might be used as an alternative to each other. A further large-scale study with at least 20 patients in each group to validate the study findings is needed. This trial is registered with NCT02871700. PMID: 32377266 [PubMed - in process]
Source: Behavioural Neurology - May 8, 2020 Category: Neurology Authors: Hsieh YW, Lin YH, Zhu JD, Wu CY, Lin YP, Chen CC Tags: Behav Neurol Source Type: research

Posterior circulation stroke: machine learning-based detection of early ischemic changes in acute non-contrast CT scans
ConclusionsQuantitative features of early hyperacute NCCTs can be used to detect early ischemic changes in pc-ASPECTS regions. The classifier performance was higher or equal to results of human raters. The proposed approach could facilitate reproducible analysis in research and may allow standardized assessments for outcome prediction and therapy planning in clinical routine.
Source: Journal of Neurology - May 10, 2020 Category: Neurology Source Type: research

Integration of ultra-high-pressure liquid chromatography –tandem mass spectrometry with machine learning for identifying fatty acid metabolite biomarkers of ischemic stroke
Chem. Commun., 2020, Advance Article DOI: 10.1039/D0CC02329A, CommunicationLijian Zhang, Fei Ma, Ao Qi, Lulu Liu, Junjie Zhang, Simin Xu, Qisheng Zhong, Yusen Chen, Chun-yang Zhang, Chun Cai We demonstrated the integration of UHPLC –MS/MS with machine learning for identifying fatty acid metabolite biomarkers of ischemic stroke. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - May 15, 2020 Category: Chemistry Authors: Lijian Zhang Source Type: research

Integration of ultra-high-pressure liquid chromatography-tandem mass spectrometry with machine learning for identifying fatty acid metabolite biomarkers of ischemic stroke.
We report for the first time the integration of ultra-high-pressure liquid chromatography-tandem mass spectrometry with machine learning for identifying fatty acid metabolite biomarkers of ischemic stroke. In particular, we develop an optimal model to discriminate ischemic stroke patients from healthy persons with 100% sensitivity and 93.18% specificity. This research may facilitate understanding the roles of fatty acid metabolites in stroke occurrence, holding great potential in clinical stroke diagnosis. PMID: 32409805 [PubMed - as supplied by publisher]
Source: Chemical Communications - May 14, 2020 Category: Chemistry Authors: Zhang L, Ma F, Qi A, Liu L, Zhang J, Xu S, Zhong Q, Chen Y, Zhang CY, Cai C Tags: Chem Commun (Camb) Source Type: research

Untargeted metabolomics predicts the functional outcome of ischemic stroke.
CONCLUSION: Metabolomics is a potential method to explore the blood biomarkers of acute ischemic stroke. The patients with unfavorable outcomes had a lower PAF level compared to those with favorable outcomes. PMID: 32414667 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - May 12, 2020 Category: General Medicine Authors: Chi NF, Chang TH, Lee CY, Wu YW, Shen TA, Chan L, Chen YR, Chiou HY, Hsu CY, Hu CJ Tags: J Formos Med Assoc Source Type: research

Mobile Application as a Learning Aid for Nurses and Nursing Students to Identify and Care for Stroke Patients: Pretest and Posttest Results.
In this study, a total of 115 nurses from health services in the South of Brazil and 35 nursing students of a community university participated. The stages focused on development, modeling of clinical cases, problem-based learning, pretest (before) app use, and posttest (after) use of the app. The results of the pretest and posttest corrections showed a substantial statistical difference (P < .001), indicating a significant knowledge gain after the use of the app, particularly in terms of the detection scales and interpretation of the imaging tests. The mSmartAVC app used at the bedside supported decision-making for det...
Source: Computers, Informatics, Nursing : CIN - May 15, 2020 Category: Nursing Authors: Baccin CRA, Dal Sasso GTM, Paixão CA, de Sousa PAF Tags: Comput Inform Nurs Source Type: research

AHA News: After Diabetes, Stroke and Heart Attack, She ' s Learning to ' Fight Smart '
Title: AHA News: After Diabetes, Stroke and Heart Attack, She ' s Learning to ' Fight Smart 'Category: Health NewsCreated: 5/21/2020 12:00:00 AMLast Editorial Review: 5/22/2020 12:00:00 AM
Source: MedicineNet Heart General - May 22, 2020 Category: Cardiology Source Type: news

Intermittent Cerebellar Theta Burst Stimulation Improves Visuo-motor Learning in Stroke Patients: a Pilot Study
In this study, we investigated the effects of cerebellar intermittent theta burst stimulation (c-iTBS), a high-frequency rTMS protocol, on visuo-motor learning in a sample of hemiparetic patients due to recent stroke in the territory of the contralateral middle cerebral artery. Eight stroke patients were enrolled for the purposes of the study in the chronic stage of recovery (i.e., at least 6  months after stroke). In two sessions, Patients were randomly assigned to treatment with real or sham c-iTBS applied over the cerebellar hemisphere ipsilateral to the affected body side. c-iTBS was applied immediately before the le...
Source: The Cerebellum - May 27, 2020 Category: Neurology Source Type: research

Intermittent Cerebellar Theta Burst Stimulation Improves Visuo-motor Learning in Stroke Patients: a Pilot Study.
In this study, we investigated the effects of cerebellar intermittent theta burst stimulation (c-iTBS), a high-frequency rTMS protocol, on visuo-motor learning in a sample of hemiparetic patients due to recent stroke in the territory of the contralateral middle cerebral artery. Eight stroke patients were enrolled for the purposes of the study in the chronic stage of recovery (i.e., at least 6 months after stroke). In two sessions, Patients were randomly assigned to treatment with real or sham c-iTBS applied over the cerebellar hemisphere ipsilateral to the affected body side. c-iTBS was applied immediately before the lea...
Source: Cerebellum - May 27, 2020 Category: Neuroscience Authors: Bonnì S, Motta C, Pellicciari MC, Casula EP, Cinnera AM, Maiella M, Picazio S, Tramontano M, Sallustio F, Koch G Tags: Cerebellum Source Type: research

Experience of enriched rehabilitation in the chronic phase of stroke.
Conclusion: A therapy program including task-specific training and environmental enrichment may provide late-phase stroke survivors with perceived improvements in functional ability, knowledge insights, perceptions of rehabilitation needs and enriching emotional impacts.Implications for rehabilitationETT is feasible and may lead to perceived improvements in function and a change of mindset, even in the chronic phase after stroke.Trust in the competence of the rehabilitation staff is an important factor in compliance with the high-intensity training in the ETT program.Given the lack of stimulation and socialization among ma...
Source: Disability and Rehabilitation - May 31, 2020 Category: Rehabilitation Authors: Vive S, Bunketorp-Käll L, Carlsson G Tags: Disabil Rehabil Source Type: research

Virtual Reality Design for Stroke Rehabilitation.
Authors: Charles D, Holmes D, Charles T, McDonough S Abstract Stroke is a leading cause of disability, and with the stroke survivor population rising in most countries it is increasingly difficult to provide optimal treatment to patients once they return home. Assistive technology solutions can potentially contribute to meeting demand, and also be cost effective. In this chapter, we consider the design and development of engaging serious virtual reality (VR) games for upper arm stroke rehabilitation. Fundamental design principles are summarised and related to our experience of creating game-based VR rehabilitation....
Source: Advances in Experimental Medicine and Biology - June 4, 2020 Category: Research Tags: Adv Exp Med Biol Source Type: research

Iterative Adjustment of Stimulation Timing and Intensity During FES-Assisted Treadmill Walking for Patients After Stroke
Functional electric stimulation (FES) is a common intervention to correct foot drop for patients after stroke. Due to the disturbances from internal time-varying muscle characteristics under electrical stimulation and external environmental uncertainties, most of the existing FES system used pre-set stimulation parameters and cannot achieve good gait performances during FES-assisted walking. Therefore, an adaptive FES control system, which used the iterative learning control to adjust the stimulation intensity based on kinematic data and a linear model to modulate the stimulation timing based on walking speed during FES-as...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - May 31, 2020 Category: Neuroscience Source Type: research

Feasibility of Wearable Sensing for In-Home Finger Rehabilitation Early After Stroke
Wearable grip sensing shows potential for hand rehabilitation, but few studies have studied feasibility early after stroke. Here, we studied a wearable grip sensor integrated with a musical computer game (MusicGlove). Among the stroke patients admitted to a hospital without limiting complications, 13% had adequate hand function for system use. Eleven subjects used MusicGlove at home over three weeks with a goal of nine hours of use. On average they achieved 4.1 ± 3.2 (SD) hours of use and completed 8627 ± 7500 grips, an amount comparable to users in the chronic phase of stroke measured in a previous st...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - May 31, 2020 Category: Neuroscience Source Type: research

Functional connectivity of the retrosplenial cortex in rats with ischemic stroke is improved by electroacupuncture.
CONCLUSION: These findings suggest that EA at GV20 and GV24 might improve the learning and memory ability of MICD rats by increasing the functional connectivity between the RSC and hippocampus, cingulate gyrus and midbrain, which is encouraging for the potential treatment for cognitive impairment secondary to ischemia stroke. PMID: 32529883 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - June 11, 2020 Category: Complementary Medicine Authors: Zhang Q, Li J, Huang S, Yang M, Liang S, Liu W, Chen L, Tao J Tags: Acupunct Med Source Type: research

Study Documents Neurological, Psychiatric Complications From COVID-19
While previous studies and case reports have found that COVID-19 patients have experienced vascular and neurological problems, a newstudy inthe Lancet Psychiatry reports that patients are also showing symptoms of psychiatric disorders, including psychosis and depression.The study was the result of a collaborative effort of specialists in the United Kingdom to document COVID-19 complications.“To our knowledge, this is the first systematic, nationwide U.K. surveillance study of the breadth of acute complications of COVID-19 in the nervous system,” wrote Aravinthan Varatharaj, M.R.C.P., of University Hospital Southampton ...
Source: Psychiatr News - June 29, 2020 Category: Psychiatry Tags: Aravinthan Varatharaj brain hemorrhage brain inflammation cognition COVID-19 depression Lancet Psychiatry pain psychiatric disorders psychosis stroke United Kingdom weakness Source Type: research

Enhanced white matter reorganization and activated brain glucose metabolism by enriched environment following ischemic stroke: Micro PET/CT and MRI study.
This study aimed to examine the effects of post-ischemic EE treatment on the brain remodeling using magnetic resonance imaging (MRI) and 18F-FDG positron emission tomography (PET). Male Sprague-Dawley rats were subjected to permanent middle cerebral artery occlusion (MCAO) and housed in standard environment (SE) or EE for consecutive 30 days. Cognitive testing was performed using the Morris water maze. White matter structural modifications were detected by MRI combined with histological analysis. In addition, PET scanning with 18F-FDG as a molecular probe was conducted to detect brain energy metabolism. Our results showed ...
Source: Neuropharmacology - June 28, 2020 Category: Drugs & Pharmacology Authors: Li M, Zhao Y, Zhan Y, Yang L, Feng X, Lu Y, Lei J, Zhao T, Wang L, Zhao H Tags: Neuropharmacology Source Type: research

The use of augmented reality for rehabilitation after stroke: a narrative review.
CONCLUSION: AR systems are currently being used for stroke rehabilitation in a variety of ways however the technology is in its infancy and warrants further investigation. A consistent definition of AR must be developed and further research is required to determine the possibilities of using AR to promote practice of occupations in a more contextually relevant environment to enhance motor learning and generalisation to other tasks. This could include using AR to bring the home environment into the hospital setting to enhance practice of prioritised occupations before returning home. IMPLICATIONS FOR REHABILITATION There is...
Source: Disability and Rehabilitation. Assistive Technology. - July 13, 2020 Category: Rehabilitation Authors: Gorman C, Gustafsson L Tags: Disabil Rehabil Assist Technol Source Type: research

AI, radiomics can predict stroke treatment success
Artificial intelligence (AI) and radiomics can help to predict if a particular...Read more on AuntMinnie.comRelated Reading: ECR 2020: COVID-19's nonpulmonary manifestations COVID-19 neuro findings marked by mental status, stroke fMRI-based machine learning helps predict coma outcomes Stroke scans drop by 40% during COVID-19 outbreak
Source: AuntMinnie.com Headlines - July 28, 2020 Category: Radiology Source Type: news

Quantitative Serial CT Imaging-Derived Features Improve Prediction of Malignant Cerebral Edema after Ischemic Stroke
ConclusionIncorporating quantitative CT-based imaging features from baseline and 24-h CT enhances identification of patients with malignant edema needing DHC. Further refinements and external validation of such imaging-based machine-learning models are required.
Source: Neurocritical Care - July 28, 2020 Category: Neurology Source Type: research

What can virtual reality offer to stroke patients? A narrative review of the literature.
CONCLUSION: The studies confirmed the effectiveness of various forms of VR treatment in the alleviation of psychological and behavioral problems and psychiatric disorders. There is a shortage of VR-based technological solutions that would, besides physical rehabilitation, offer stroke patients therapeutic tools to alleviate psychological disturbance and improve the patient's mood and motivation. Such solutions will most likely become a field of intensive research in the coming years. PMID: 32741792 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - August 5, 2020 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Toward automatic evaluation of medical abstracts: The current value of sentiment analysis and machine learning for classification of the importance of PubMed abstracts of randomized trials for stroke
The exponential growth of the number of medical publications makes it more and more difficult for the clinical practitioner to keep track of relevant scientific progress. Computer-aided screening and analysis might help to overview and classify the content of medical publications more efficiently. The new wave of enthusiasm for machine learning algorithms has launched several new possibilities to analyze and categorize documents, ranging from sports news to hospital discharge summaries. Search algorithms for the medical literature, i.e.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Igor Fischer, Hans-Jakob Steiger Source Type: research

Machine learning is a valid method for predicting prehospital delay after acute ischemic stroke
ConclusionsMachine learning algorithms were not inferior to logistic regression models for prediction of prehospital delay after stroke. All models provided good discrimination, thereby creating valuable diagnostic programs for prehospital delay prediction.
Source: Brain and Behavior - August 17, 2020 Category: Neurology Authors: Li Yang, Qinqin Liu, Qiuli Zhao, Xuemei Zhu, Ling Wang Tags: ORIGINAL RESEARCH Source Type: research

Using Transcranial Direct Current Stimulation to Augment the Effect of Motor Imagery-Assisted Brain-Computer Interface Training in Chronic Stroke Patients —Cortical Reorganization Considerations
Conclusion: MI-BCI improved the motor function of the stroke-affected arm in chronic stroke patients with moderate to severe impairment. tDCS did not confer overall additional benefit although there was a trend toward greater benefit. Cortical activity changes in the contralesional M1 associated with functional improvement suggests a possible role for the contralesional M1 in stroke recovery in more severely affected patients. This has important implications in designing neuromodulatory interventions for future studies and tailoring treatment.Clinical Trial Registration: The study was registered at https://clinicaltrials.gov (NCT01897025).
Source: Frontiers in Neurology - August 26, 2020 Category: Neurology Source Type: research

Cardiovascular/stroke risk prevention: A new machine learning framework integrating carotid ultrasound image-based phenotypes and its harmonics with conventional risk factors.
CONCLUSION: The AtheroRisk-integrated ML system outperforms the AtheroRisk-conventional ML system using RF classifier. PMID: 32861380 [PubMed - in process]
Source: Indian Heart J - June 30, 2020 Category: Cardiology Authors: Jamthikar A, Gupta D, Khanna NN, Saba L, Laird JR, Suri JS Tags: Indian Heart J Source Type: research

Proteomics-Guided Study on Buyang Huanwu Decoction for Its Neuroprotective and Neurogenic Mechanisms for Transient Ischemic Stroke: Involvements of EGFR/PI3K/Akt/Bad/14-3-3 and Jak2/Stat3/Cyclin D1 Signaling Cascades
AbstractBuyang Huanwu Decoction (BHD), a classic traditional Chinese medicine (TCM) formula, has been used for recovering neurological dysfunctions and treating post-stroke disability in China for 200  years. In the present study, we investigated the effects of BHD on inhibiting neuronal apoptosis, promoting proliferation and differentiation of neural stem cells (NSCs) and neurite formation and enhancing learning and memory functional recovery in an experimental rat ischemic stroke model. BHD si gnificantly reduced infarct volume and decreased cell apoptosis in the ischemic brain. BHD enhanced neuronal cell viability in v...
Source: Molecular Neurobiology - September 2, 2020 Category: Neurology Source Type: research

Quantile Regression Forests to Identify Determinants of Neighborhood Stroke Prevalence in 500 Cities in the USA: Implications for Neighborhoods with High Prevalence
AbstractStroke exerts a massive burden on the US health and economy. Place-based evidence is increasingly recognized as a critical part of stroke management, but identifying the key determinants of neighborhood stroke prevalence and the underlying effect mechanisms is a topic that has been treated sparingly in the literature. We aim to fill in the research gaps with a study focusing on urban health. We develop and apply analytical approaches to address two challenges. First, domain expertise on drivers of neighborhood-level stroke outcomes is limited. Second, commonly used linear regression methods may provide incomplete a...
Source: Journal of Urban Health - September 3, 2020 Category: Health Management Source Type: research

Predictors of Successful First-Pass Thrombectomy with a Balloon Guide Catheter: Results of a Decision Tree Analysis
AbstractComplete recanalization after a single retrieval maneuver is an interventional goal in acute ischemic stroke and an independent factor for good clinical outcome. Anatomical biomarkers for predicting clot removal difficulties have not been comprehensively analyzed and await unused. We retrospectively evaluated 200 consecutive patients who suffered acute stroke and occlusion of the anterior circulation and were treated with mechanical thrombectomy through a balloon guide catheter (BGC). The primary objective was to evaluate the influence of carotid tortuosity and BGC positioning on the one-pass Modified Thrombolysis ...
Source: Translational Stroke Research - September 10, 2020 Category: Neurology Source Type: research

Post-Stroke Cognitive Impairments and Responsiveness to Motor Rehabilitation: A Review
AbstractPurpose of ReviewThis review discusses the prevalence of cognitive deficits following stroke and their impact on responsiveness to therapeutic intervention within a motor learning context.Recent FindingsClinical and experimental studies have established that post-stroke cognitive and motor deficits may impede ambulation, augment fall risk, and influence the efficacy of interventions. Recent research suggests the presence of cognitive deficits may play a larger role in motor recovery than previously understood.SummaryConsidering that cognitive impairments affect motor relearning, post-stroke motor rehabilitation the...
Source: Current Physical Medicine and Rehabilitation Reports - September 9, 2020 Category: Rehabilitation Source Type: research

Oleuropein Improved Post Cerebral Stroke Cognitive Function by Promoting Histone Acetylation and Phosphorylation of cAMP Response Element-Binding Protein in MCAO Rats.
Conclusion: treatment of OLP improved PSCI via increasing the phosphorylation of CREB and histone acetylation, thus attenuating cholinergic activity. PMID: 32922228 [PubMed]
Source: Dose Response - June 30, 2020 Category: Drugs & Pharmacology Authors: Gao Y, Li X, Xu R, Guo Y, Yin H, Tan R, Qi Z, Liu G, Liang J, Ya B Tags: Dose Response Source Type: research

A Novel Multiple-Cue Observational Clinical Scale for Functional Evaluation of Gait After Stroke - The Stroke Mobility Score (SMS).
CONCLUSIONS The SMS proves to be an easy-to-use, tele-applicable, robust, consistent, reliable, and nuanced functional scale of gait impairments after stroke. Due to its sensitivity to whole-body motion criteria, it is ideally suited for machine learning algorithms and for development of new therapy strategies based on instrumented gait analysis. PMID: 32930152 [PubMed - in process]
Source: Medical Science Monitor - September 17, 2020 Category: Research Tags: Med Sci Monit Source Type: research

Recovery after stroke: perspectives of young stroke survivors in Taiwan.
CONCLUSION: These findings provide useful insights for rehabilitation clinicians to develop culturally tailored interventions to improve poststroke recovery outcomes in young stroke survivors. Implications for rehabilitation Rehabilitation clinicians should understand stroke survivors' beliefs and goals of recovery to provide tailored services. Optimizing the goal-setting process and patient-provider communication may help clinicians and survivors examine and adjust their expectations toward recovery during rehabilitation. Interventions will be needed to address personal and environmental supports and barriers, such as mot...
Source: Disability and Rehabilitation - September 14, 2020 Category: Rehabilitation Authors: Chang FH, Lin YN, Liou TH Tags: Disabil Rehabil Source Type: research

Defining reperfusion post endovascular therapy in ischemic stroke using MR-dynamic contrast enhanced perfusion.
CONCLUSION: MR perfusion following EVT provides accurate physiological approach to understanding the relationship of CBF, clinical outcome, and DWI growth. ADVANCES IN KNOWLEDGE: MR perfusion CBF acquired is a robust, objective reperfusion measurement providing following recanalization of the target occlusion which is critical to distinguish potential therapeutic harm from the failed technical success of EVT as well as improve the responsiveness of clinical trial outcomes to disease modification. PMID: 32941770 [PubMed - as supplied by publisher]
Source: The British Journal of Radiology - September 16, 2020 Category: Radiology Authors: d'Esterre CD, Sah RG, Assis Z, Talai AS, Demchuk AM, Hill MD, Goyal M, Lee TY, Forkert ND, Barber PA Tags: Br J Radiol Source Type: research

Artificial Intelligence and Stroke Imaging
This article addresses this topic and seeks to present an overview of machine learning and/or deep learning applied to stroke imaging.
Source: Neuroimaging Clinics - September 17, 2020 Category: Radiology Authors: Guangming Zhu, Bin Jiang, Hui Chen, Elizabeth Tong, Yuan Xie, Tobias D. Faizy, Jeremy J. Heit, Greg Zaharchuk, Max Wintermark Source Type: research

IgA natural antibodies are produced following T-cell independent B-cell activation following stroke.
Abstract Up to 30% of stroke patients experience cognitive decline within one year of their stroke. There are currently no FDA-approved drugs that can prevent post-stroke cognitive decline, in part due to a poor understanding of the mechanisms involved. We have previously demonstrated that a B-lymphocyte response to stroke, marked by IgA+ cells, can cause delayed cognitive dysfunction in mice and that a similar adaptive immune response occurs in the brains of some human stroke patients that suffer from vascular dementia. The stimuli which trigger B-lymphocyte activation following stroke, and their target antigens,...
Source: Brain, Behavior, and Immunity - September 17, 2020 Category: Neurology Authors: Zbesko JC, Frye JB, Becktel DA, Gerardo DK, Stokes J, Calderon K, Nguyen TV, Bhattacharya D, Doyle KP Tags: Brain Behav Immun Source Type: research

Executive function following pediatric stroke. A systematic review.
DISCUSSION: Our results highlight the importance to assess EF following pediatric stroke. Early identification of difficulties in EF is crucial to provide adequate training to the children and to prevent the development of other correlated difficulties, such as behavioral problems or learning difficulties. Methodological issues regarding the heterogeneity of samples and measurement difficulties limit the conclusions that can be made about the clinical predictors of the outcomes. Studies are needed to better understand this aspect and to develop adequate EF interventions for children following stroke. PMID: 32969322 [P...
Source: Child Neuropsychology - September 23, 2020 Category: Child Development Authors: Rivella C, Viterbori P Tags: Child Neuropsychol Source Type: research

The three-phase enriched environment paradigm promotes neurovascular restorative and prevents learning impairment after ischemic stroke in rats.
Abstract Enriched environment (EE) with a complex combination of sensorimotor, cognitive and social stimulations has been shown to enhance brain plasticity and improve recovery of functions in animal models of stroke. The present study extended these findings by assessing whether the three-phase EE intervention paradigm would improve neurovascular remodeling following ischemic stroke. Male Sprague-Dawley rats were subjected to permanent middle cerebral artery occlusion (MCAO). A three-phase EE intervention paradigm was designed in terms of the different periods of cerebral ischemia by periodically rearranging the ...
Source: Neurobiology of Disease - September 22, 2020 Category: Neurology Authors: Zhan Y, Li MZ, Yang L, Feng XF, Lei JF, Zhang N, Zhao YY, Zhao H Tags: Neurobiol Dis Source Type: research

Kinematic parameters obtained with the ArmeoSpring for upper-limb assessment after stroke: a reliability and learning effect study for guiding parameter use
After stroke, kinematic measures obtained with non-robotic and robotic devices are highly recommended to precisely quantify the sensorimotor impairments of the upper-extremity and select the most relevant ther...
Source: Journal of NeuroEngineering and Rehabilitation - September 29, 2020 Category: Rehabilitation Authors: Nabila Brihmat, Isabelle Loubinoux, Evelyne Castel-Lacanal, Philippe Marque and David Gasq Tags: Research Source Type: research

Cardiac myxoma and ischemic stroke
We report a case of intra-arterial tirofiban administration in a patient with acute ischemic stroke due to left atrial myxoma. Our purpose is to increase awareness at evaluation of secondary causes of ischemic stroke and provide a treatment option.Cardiac myxoma, which is most commonly found in the left atrium, is a rare etiology of cardioembolic stroke.1 The diagnosis of cardiac myxoma is seldom found at the onset of cerebral embolism when considering emergency endovascular treatment. We present a case of a 52-year-old Chinese male who had an ischemic stroke caused by left atrial myxoma, followed by an obvious recovery af...
Source: QJM - March 6, 2020 Category: Internal Medicine Source Type: research

Do epilepsy and migraine share a genetic link?
Conclusion This paper suggests there is a link between the number of close relatives with a seizure disorder and the likelihood that an individual with epilepsy will also suffer from migraines with aura. However, it seems that the researchers were only interested in what they term ‘additional’ family members, and did not take into account the fact that to be eligible for this study at least two siblings or a parent and child both had to suffer from epilepsy. There seems to be the possibility that if, for example, four members of a family were enrolled in the study but the family had no further affected members, all me...
Source: NHS News Feed - January 7, 2013 Category: Consumer Health News Tags: Neurology Genetics/stem cells Source Type: news

Apophis – a 'potentially hazardous' asteroid – flies by Earth on Wednesday | Stuart Clark
Asteroid Apophis arrives this week for a close pass of Earth. This isn't the end of the world but a new beginning for research into potentially hazardous asteroidsApophis hit the headlines in December 2004. Six months after its discovery, astronomers had accrued enough images to calculate a reasonable orbit for the 300-metre chunk of space rock. What they saw was shocking. There was a roughly 1 in 300 chance of the asteroid hitting Earth during April 2029. Nasa issued a press release spurring astronomers around the world to take more observations in order to refine the orbit. Far from dropping, however, the chances of an i...
Source: Guardian Unlimited Science - January 7, 2013 Category: Science Authors: Stuart Clark Tags: Blogposts Astronomy guardian.co.uk Space Science Source Type: news

Apophis: why Nasa takes a special interest in the asteroid's latest pass
Asteroid Apophis arrives this week for a close pass of Earth. This isn't the end of the world but a new beginning for research into potentially hazardous asteroidsApophis hit the headlines in December 2004. Six months after its discovery, astronomers had accrued enough images to calculate a reasonable orbit for the 300-metre chunk of space rock. What they saw was shocking. There was a roughly 1 in 300 chance of the asteroid hitting Earth during April 2029. Nasa issued a press release spurring astronomers around the world to take more observations in order to refine the orbit. Far from dropping, however, the chances of an i...
Source: Guardian Unlimited Science - January 9, 2013 Category: Science Authors: Stuart Clark Tags: Blogposts Astronomy guardian.co.uk Space Science Source Type: news

What will be the next great invention? Ask a teenager
From the lightbulb to the web, the British have a great history of innovation. We must help young people to keep inspiring usFrom the sewing machine to ice cream, the railway to the telegraph, the 19th century was awash with invention. It seems you couldn't turn your back without someone inventing the flushing toilet, the typewriter, the light bulb, X-ray, or the wireless.The Victorians certainly had a knack for recognising a need, an opportunity, a better way of doing things – as a recent poll of Britain's greatest inventions shows. And recognising needs is what innovation is all about. It's not about widgets for the sa...
Source: Guardian Unlimited Science - January 9, 2013 Category: Science Authors: Maggie Philbin Tags: Comment guardian.co.uk Society Technology UK news Young people Education Science Comment is free Source Type: news

NIH launches collaborative effort to find biomarkers for Parkinson's
(NIH/National Institute of Neurological Disorders and Stroke) The National Institutes of Health has launched a new initiative to help researchers investigate biomarkers for Parkinson's disease, and to help patients learn about and participate in such studies. So far, the NINDS Parkinson's Disease Biomarkers Program has funded nine research teams taking a variety of unique approaches to discover new biomarkers. To support collaboration across these projects and others, the PDBP is introducing a new online platform for investigators to share their data.
Source: EurekAlert! - Medicine and Health - January 15, 2013 Category: Global & Universal Source Type: news

Wisconsin Women Encouraged to Learn Heart Health Facts on "Wear Red Day" Today
Women are encouraged to learn about their heart health risks as First Lady Tonette Walker and state health officials today mark the 10th anniversary of “Wear Red Day,” an American Heart Association (AHA) event to raise awareness about heart disease and stroke risks among women.
Source: Wisconsin DHFS Press Releases - February 1, 2013 Category: Hospital Management Source Type: news

Paralysed people could get movement back through thought-control
Brain implant could allow people to 'feel' the presence of infrared light and one day be used to move artificial limbsScientists have moved closer to allowing paralysed people to control artificial limbs with their thoughts following a breakthrough in technology that gave rats an extra sense.A brain implant that allows the animals to "feel" the presence of invisible infrared light could one day be used to provide paralysed people with feedback as they move artificial limbs with their thoughts, or it could even extend a person's normal range of senses.Miguel Nicolelis, a neurobiologist at Duke University in North Carolina w...
Source: Guardian Unlimited Science - February 17, 2013 Category: Science Authors: Alok Jha Tags: The Guardian Animal research United States AAAS World news Technology Neuroscience Source Type: news