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Test−Retest Reliability and Convergent Validity of Three Manual Dexterity Measures in Persons With Chronic Stroke
Conclusion The test−retest reliability of the BBT, NHPT and mSHFT was high but all measures showed learning effects. The relationships between the 3 measures indicate that they partly complement one another. The BBT may be preferred for persons with moderate impairments of the upper extremity and the NHPT and the mSHFT for persons with milder impairments. As the mSHFT has the advantage of reflecting activities in daily life it may be a suitable alternative to the NHPT.
Source: PMandR - March 24, 2016 Category: Rehabilitation Source Type: research

A lesion to learn: Stroke mimics
Publication date: Available online 26 March 2016 Source:Apollo Medicine Author(s): Mahir Meman, Pushpendra Nath Renjen, Dinesh M. Chaudhari Acute ischemic stroke with neurological deficit is a very debilitating condition, especially in younger patients. IV thrombolysis is the only effective treatment available in most of the centers across India. But delay in hospitalization and bleeding complications are major limitations. In addition to that, stroke mimics are another big problem. Correct identification of stroke mimics needs clinical expertise and imaging studies. Multiple studies indicate safety of thrombolysis in...
Source: Apollo Medicine - March 25, 2016 Category: Journals (General) Source Type: research

Computer Imagery and Neurological Rehabilitation: On the Use of Augmented Reality in Sensorimotor Training to Step Up Naturally Occurring Cortical Reorganization in Patients Following Stroke.
Authors: Correa-Agudelo E, Ferrin C, Velez P, Gomez JD Abstract This work promotes the use of computer-generated imagery -as visual illusions- to speed up motor learning in rehabilitation. In support of this, we adhere the principles of experience-dependent neuroplasticity and the positive impact of virtual reality (VR) thereof. Specifically, post-stroke patients will undergo motor therapy with a surrogate virtual limb that fakes the paralyzed limb. Along these lines, their motor intentions will match the visual evidence, which fosters physiological, functional and structural changes over time, for recovery of lost...
Source: Studies in Health Technology and Informatics - April 6, 2016 Category: Information Technology Tags: Stud Health Technol Inform Source Type: research

Kinematic and Kinetic Outcome of Robot Assisted Neurorehabilitation in Chronic Moderate-to-Severe Hemiparetic Stroke (P3.298)
Conclusions: RT+TTT was not significantly different from RT alone, suggesting that TTT did not interfere with motor learning conferred by RT. Study Supported by: American Academy of Neurology (AAN) and the VA Department of Research and Development VA Merit Award B6935RDisclosure: Dr. Iqbal has nothing to disclose. Dr. Conroy has nothing to disclose. Dr. Roy has nothing to disclose. Dr. Bever has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Iqbal, T., Conroy, S., Roy, A., Bever, C. Tags: Neurorehabilitation Source Type: research

Recurrent Alternating Homonymous Hemianopia Due to Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-Like Episodes (MELAS) (P4.260)
CONCLUSIONS: We describe a unique phenomenon of recurrent alternating homonymous hemianopia in MELAS, which should prompt consideration of this diagnosis.Disclosure: Dr. Krysko has nothing to disclose. Dr. Arun has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Krysko, K., Arun, S. Tags: Neuro-ophthalmology/Neuro-otology Source Type: research

Spatial-Motor Flexibility (SMF) and Post-Stroke Cognitive Recovery (P6.014)
Conclusions:The ability to direct movement flexibly in the side of body-centered space near impaired limbs may be needed for optimal functional stroke recovery. The clicker test provides an easy way to assess this ability and its performance may also reflect functioning of executive-action systems. Further studies examining whether SMF deficits predict cognitive recovery in stroke survivors more generally are needed.Disclosure: Dr. Barrett has received personal compensation for activities with Kessler Foundation as an employee. Dr. Barrett has received research support from SPR therapeutics. Dr. Zhang has nothing to disclo...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Barrett, A., Zhang, R., Frey, S., Oh-Park, M. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

Knowledge Translation in Right Brain Rehabilitation: A Feasibility Study of Prism Treatment After Acute Stroke (P6.210)
Conclusions:Fewer patients had spatial neglect than expected, but we demonstrated feasible knowledge translation for spatial neglect care in an underserved setting. An active-learning approach may be key to clinician engagement. Future research in stroke centers will help clarify the impact of neglect assessment and treatment on quality outcomes.Disclosure: Dr. Barrett has received personal compensation for activities with Kessler Foundation as an employee. Dr. Barrett has received research support from SPR therapeutics. Dr. Chen has nothing to disclose. Dr. Hreha has received personal compensation for activities with Kess...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Barrett, A., Chen, P., Hreha, K., Alban, F., Gocon, C., Santos, C., Lawless, K., LaRosa, J. Tags: Behavioral and Cognitive Neurology: Brain-behavior Correlations Source Type: research

High blood pressure: Why me?
“I go to the gym, and I never add salt. So why do I have high blood pressure?” Despite its astonishing prevalence of one in three Americans, many people struggle with the diagnosis of high blood pressure, or hypertension. It’s worth exploring why, because being an active participant in your care is crucial for optimal blood pressure control. Certain features make any diagnosis easier to accept: First, people are more likely to accept a diagnosis if they have symptoms. A person with cough and fever will believe a diagnosis of pneumonia. But someone who feels fine would not. Next, people more readily accept a diagnosi...
Source: New Harvard Health Information - May 2, 2016 Category: Consumer Health News Authors: Naomi D. L. Fisher, MD Tags: Behavioral Health Health care Heart Health Hypertension and Stroke Prevention Screening high blood pressure Source Type: news

Cardiorespiratory fitness and cognitive functioning following short-term interventions in chronic stroke survivors with cognitive impairment: a pilot study
This study, a quasi-experimental, one-group pretest–post-test design, evaluated the effects on cognitive functioning and cardiorespiratory fitness of 8-week interventions (aerobic exercise alone and aerobic exercise and cognitive training combined) in patients with chronic stroke and cognitive impairment living in the community (participants: n=14, 61.93±9.90 years old, 51.50±38.22 months after stroke, n=7 per intervention group). Cognitive functions and cardiorespiratory fitness were evaluated before and after intervention, and at a 3-month follow-up visit (episodic memory: revised-Hopkins Verbal Learning Test; workin...
Source: International Journal of Rehabilitation Research - May 3, 2016 Category: Rehabilitation Tags: Original articles Source Type: research

Alpha-linolenic acid given as enteral or parenteral nutritional intervention against sensorimotor and cognitive deficits in a mouse model of ischemic stroke.
This study evaluated the value of ALA as adjunctive therapy for stroke recovery by comparing whether oral or intravenous supplementation of ALA best support recovery from ischemia. Motor and cognitive deficits were assessed using rotarod, pole and Morris water maze tests. ALA supplementation in diet was better than intravenous treatment in improving motor coordination, but this improvement was not due to a neuroprotective effect since infarct size was not reduced. Both types of ALA supplementation improved spatial learning and memory after stroke. This cognitive improvement correlated with higher survival of hippocampal ne...
Source: Neuropharmacology - April 27, 2016 Category: Drugs & Pharmacology Authors: Bourourou M, Heurteaux C, Blondeau N Tags: Neuropharmacology Source Type: research

Ischemic Stroke
Each year, more than 795,000 people in the United States suffer a stroke and by 2030, it is estimated that 4% of the U.S. population will have had a stroke. Home healthcare clinicians will be increasingly called upon to assist stroke survivors and their caregivers adjust to disability and assist the survivor during their reintegration into the community. Therapeutic modalities are changing with advanced technology. Great strides are being made in the treatment of acute stroke; particularly endovascular interventions. More patients are surviving the acute stroke event and therefore will need to learn how to live with variou...
Source: Home Healthcare Nurse - May 1, 2016 Category: Nursing Tags: Feature Source Type: research

Vascular Risk Factors and Diseases Modulate Deficits of Reward-Based Reversal Learning in Acute Basal Ganglia Stroke
Conclusions The previously reported impairment of reward-based learning may be attributed to vascular risk factors and associated diseases, which are enriched in stroke patients. This study emphasizes the necessity of appropriate control subjects in cognition studies.
Source: PLoS One - May 9, 2016 Category: Biomedical Science Authors: Ulla K. Seidel Source Type: research

Effect of a mixed reality-based intervention on arm, hand, and finger function on chronic stroke
Virtual and mixed reality systems have been suggested to promote motor recovery after stroke. Basing on the existing evidence on motor learning, we have developed a portable and low-cost mixed reality tabletop...
Source: Journal of NeuroEngineering and Rehabilitation - May 11, 2016 Category: Rehabilitation Authors: Carolina Colomer, Roberto Llorens, Enrique Noé and Mariano Alcañiz Source Type: research

I Never Thought Stroke Would Happen to Me
by Myra Wilson, Stroke Survivor On November 3, 2014, I was in nursing school working as a student nurse at a hospital in Seattle. My first sign that something was not quite right was when I was walking through the nursing station and both of my eyes went blurry. I could still see color but I couldn't see letters. It was blurry for about 30 seconds before clearing up again. I was going to lunch and went to give a report to another nurse. The nurse noticed while I was speaking that I slurred my speech. I didn't notice my speech was slurred at all. It was at that time that I experienced a sudden sharp pain on the right s...
Source: Healthy Living - The Huffington Post - May 13, 2016 Category: Consumer Health News Source Type: news

Electroacupuncture ameliorates post-stroke learning and memory through minimizing ultrastructural brain damage and inhibiting the expression of MMP-2 and MMP-9 in cerebral ischemia-reperfusion injured rats.
Authors: Lin R, Yu K, Li X, Tao J, Lin Y, Zhao C, Li C, Chen LD Abstract The aim of the present study was to investigate the potential neuroprotective effects of electroacupuncture (EA) in the treatment of cerebral ischemia/reperfusion (I/R) injury, and to elucidate the association between this neuroprotective effect and brain ultrastructure and expression of matrix metalloproteinase (MMP)‑2 and 9. Rats underwent focal cerebral I/R injury by arterial ligation and received in vivo therapeutic EA at the Baihui (DU20) and Shenting (DU24) acupoints. The therapeutic efficacy was then evaluated following the surgery....
Source: Molecular Medicine Reports - May 15, 2016 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Different stroke(s)
A 13-year-old boy with mild learning difficulties presented to his district general hospital after an unwitnessed episode of collapse with vomiting but no loss of consciousness. He had 3 days of lethargy and intermittent occipital headaches waking him from sleep. Two days later, after another ‘funny turn’, he represented with right-side paraesthesia, weakness and word-finding difficulty. He had three previous ‘collapses’ over the last 6 months, including symptoms of transient dizziness, slurred speech, dribbling, difficulty swallowing and left-facial paraesthesia from which he had recovere...
Source: Archives of Disease in Childhood - Education and Practice - May 17, 2016 Category: Pediatrics Authors: Mundada, V., Krishnakumar, D., Chitre, M., Das, T. Tags: Oncology, Eye Diseases, Drugs: cardiovascular system, Echocardiography, Headache (including migraine), Infection (neurology), Neurooncology, Pain (neurology), Stroke, Hypertension, Ophthalmology, Valvar diseases, Radiology, Rheumatology, Dermatology, Clin Source Type: research

Stroke
This 18-month-old girl developed left-sided focal seizures, left arm and leg weakness 3 days after an uncomplicated appendicectomy. She had been previously well, and the surgery was uneventful. An urgent cranial MR scan was performed under general anaesthetic within 12 h of the onset of symptoms. Look at the selected images from this study and answer the following questions. Read on to confirm the answers and learn more about the use of diffusion-weighted imaging (DWI) in this condition. Questions There is evidence of acute intracerebral haemorrhage. (True or false?) The abnormality is in the left middle cerebral...
Source: Archives of Disease in Childhood - Education and Practice - May 17, 2016 Category: Pediatrics Authors: Williams, H. Tags: Oncology, Illuminations, Epilepsy and seizures, Stroke, Child health, Other anaesthesia Source Type: research

Combining Dopaminergic Facilitation with Robot-Assisted Upper Limb Therapy in Stroke Survivors: A Focused Review
ABSTRACT: Despite aggressive conventional therapy, lasting hemiplegia persists in a large percentage of stroke survivors. The aim of this article is to critically review the rationale behind targeting multiple sites along the motor learning network by combining robotic therapy with pharmacotherapy and virtual reality–based reward learning to alleviate upper extremity impairment in stroke survivors. Methods for personalizing pharmacologic facilitation to each individual’s unique biology are also reviewed. At the molecular level, treatment with levodopa was shown to induce long-term potentiation-like and practice-depende...
Source: American Journal of Physical Medicine and Rehabilitation - May 21, 2016 Category: Rehabilitation Tags: Literature Review Source Type: research

Neurological Recovery of Upper Extremity in Stroke Woman after 5 Years: A Case Report.
This report describes the case of a stroke patient who gained upper extremity motor recovery after 5 years, which is beyond the normal recovery period. Although the patient does not have functionality, she has partial motor recovery, and she is enthusiastic about learning to gain better use of her hand. However there is still limited evidence to use in designing effective intervention and proper timing of rehabilitation administered by personnel in training chronic stroke patients. Therefore, evidence based on neuroplasticity and neurological recovery in chronic stroke patients, including rehabilitation intervention, is pr...
Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet - June 10, 2016 Category: Journals (General) Tags: J Med Assoc Thai Source Type: research

The Zürich Maxi Mental Status Inventory (ZüMAX): Test-Retest Reliability and Discriminant Validity in Stroke Survivors
Conclusion: The ZüMAX has moderate to good test-retest reliability. Furthermore, the tool might discriminate between healthy persons and chronic stroke survivors on three of five subscales. The ZüMAX shows promise in measuring neuropsychological disturbances in stroke survivors; however, further trials are required with larger samples.
Source: Cognitive and Behavioral Neurology - June 1, 2016 Category: Neurology Tags: Original Studies Source Type: research

Upper Extremity Functional Evaluation by Fugl-Meyer Assessment Scoring Using Depth-Sensing Camera in Hemiplegic Stroke Patients
by Won-Seok Kim, Sungmin Cho, Dongyoub Baek, Hyunwoo Bang, Nam-Jong Paik Virtual home-based rehabilitation is an emerging area in stroke rehabilitation. Functional assessment tools are essential to monitor recovery and provide current function-based rehabilitation. We developed the Fugl-Meyer Assessment (FMA) tool using Kinect (Microsoft, USA) and validated it for hemiplegic stroke patients. Forty-one patients with hemiplegic stroke were enrolled. Thirteen of 33 items were selected for upper extremity motor FMA. One occupational therapist assessed the motor FMA while recording upper extremity motion with Kinect. FMA score...
Source: PLoS One - June 30, 2016 Category: Biomedical Science Authors: Won-Seok Kim Source Type: research

For the good of your heart: Keep holding the salt
Your doctor has probably told you to cut back on salt, especially if you have high blood pressure. For years we’ve understood that excess salt raises blood pressure and increases deaths from heart disease. The guilty element is sodium, which pairs with chloride to form common salt. So when the journal Lancet recently published a study reporting that low dietary sodium was associated with an increased risk of heart disease and death, controversy was predictable. A wealth of rigorous scientific studies supports a link between excess sodium intake and high blood pressure, heart attacks, and strokes. Yet the Lancet paper rep...
Source: New Harvard Health Information - July 11, 2016 Category: Consumer Health News Authors: Naomi D. L. Fisher, MD Tags: Healthy Eating Heart Health Hypertension and Stroke Prevention Source Type: news

Stroke Heroes 2016
The American Heart Association/American Stroke Association's Puget Sound Division, along with our sponsor Medtronic, congratulates the honorees for this year's Stroke Hero Awards. We had amazing stories sent to us. Thank you to all of you who submitted a nomination. Here are some of the inspiring individuals honored this year as a Stroke Hero. AMY MOORE, Stroke Survivor Amy is described as a truly an inspiring person who has never let her stroke stop her from accomplishing her goals. Her stroke was diagnosed at six months of age and left her legally blind. Amy learned Braille during her first two years of high school an...
Source: Healthy Living - The Huffington Post - July 12, 2016 Category: Consumer Health News Source Type: news

Crew resource management and simulator training in acute stroke therapy.
CONCLUSION: Even though our data do not allow positive effects on patient outcomes to be inferred, the implementation of a CRM-based stroke team and simulator training has had multiple positive effects on the workflow and work satisfaction in the treatment of acute stroke patients. PMID: 27431675 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - July 17, 2016 Category: Neurology Authors: Tahtali D, Bohmann F, Rostek P, Misselwitz B, Reihs A, Heringer F, Jahnke K, Steinmetz H, Pfeilschifter W Tags: Nervenarzt Source Type: research

Decoding post-stroke motor function from structural brain imaging
Publication date: Available online 2 August 2016 Source:NeuroImage: Clinical Author(s): Jane M. Rondina, Maurizio Filippone, Mark Girolami, Nick S. Ward Clinical research based on neuroimaging data has benefited from machine learning methods, which have the ability to provide individualized predictions and to account for the interaction among units of information in the brain. Application of machine learning in structural imaging to investigate diseases that involve brain injury presents an additional challenge, especially in conditions like stroke, due to the high variability across patients regarding characteristics of ...
Source: NeuroImage: Clinical - August 2, 2016 Category: Radiology Source Type: research

Quality Improvement in Acute Ischemic Stroke Care in Taiwan: The Breakthrough Collaborative in Stroke
by Fang-I Hsieh, Jiann-Shing Jeng, Chang-Ming Chern, Tsong-Hai Lee, Sung-Chun Tang, Li-Kai Tsai, Hsun-Hsiang Liao, Hang Chang, Kenneth A. LaBresh, Hung-Jung Lin, Hung-Yi Chiou, Hou-Chang Chiu, Li-Ming Lien, for the BTS-Stroke Investigators In the management of acute ischemic stroke, guideline adherence is often suboptimal, particularly for intravenous thrombolysis or anticoagulation for atrial fibrillation. We sought to improve stroke care quality via a collaborative model, the Breakthrough Series (BTS)-Stroke activity, in a nationw ide, multi-center activity in Taiwan. A BTS Collaborative, a short-term learning system fo...
Source: PLoS One - August 2, 2016 Category: Biomedical Science Authors: Fang-I Hsieh Source Type: research

A Clinically Relevant Method of Analyzing Continuous Change in Robotic Upper Extremity Chronic Stroke Rehabilitation
Conclusions. The expanded analyses indicated that changes across time can occur in different ways but achieve similar goals and may be influenced by individual factors such as initial movement time. These findings will guide decisions regarding treatment planning based on rates of motor relearning during upper extremity stroke robotic interventions.
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Massie, C. L., Du, Y., Conroy, S. S., Krebs, H. I., Wittenberg, G. F., Bever, C. T., Whitall, J. Tags: Clinical Research Articles Source Type: research

Home-based hand rehabilitation after chronic stroke: Randomized, controlled single-blind trial comparing the MusicGlove with a conventional exercise program.
Abstract Individuals with chronic stroke have limited options for hand rehabilitation at home. Here, we sought to determine the feasibility and efficacy of home-based MusicGlove therapy. Seventeen participants with moderate hand impairment in the chronic phase of stroke were randomized to 3 wk of home-based exercise with either the MusicGlove or conventional tabletop exercises. The primary outcome measure was the change in the Box and Blocks test score from baseline to 1 mo posttreatment. Both groups significantly improved their Box and Blocks test score, but no significant difference was found between groups. The...
Source: J Rehabil Res Dev - August 18, 2016 Category: Rehabilitation Authors: Zondervan DK, Friedman N, Chang E, Zhao X, Augsburger R, Reinkensmeyer DJ, Cramer SC Tags: J Rehabil Res Dev Source Type: research

Dissociating spatial and spatiotemporal aspects of navigation ability in chronic stroke patients.
Conclusions: Our findings showed that spatial and spatiotemporal performance was closely associated in most patients. Nonetheless, the study also provided partial support for the notion of separate space- and time-based processing mechanisms in the context of navigation. This distinction is of particular relevance to the investigation into the cognitive structure underlying navigation behavior. (PsycINFO Database Record (c) 2016 APA, all rights reserved)
Source: Neuropsychology - February 10, 2016 Category: Neurology Authors: Claessen, Michiel H. G.; Visser-Meily, Johanna M. A.; Jagersma, Elbrich; Braspenning, Merel E.; van der Ham, Ineke J. M. Source Type: research

Neurofeedback-based motor imagery training for rehabilitation after stroke.
Abstract Mental training, including motor observation and motor imagery, has awakened much academic interest. The presumed functional equivalence of motor imagery and motor execution has given hope that mental training could be used for motor rehabilitation after a stroke. Results obtained from randomized controlled trials have shown mixed results. Approximately half of the studies demonstrate positive effects of motor imagery training but the rest do not show an additional benefit. Possible reasons why motor imagery training has so far not become established as a robust therapeutic approach are discussed in detai...
Source: Der Nervenarzt - August 29, 2016 Category: Neurology Authors: Dettmers C, Braun N, Büsching I, Hassa T, Debener S, Liepert J Tags: Nervenarzt Source Type: research

Slacklining and stroke: A rehabilitation case study considering balance and lower limb weakness.
Authors: Gabel CP, Rando N, Melloh M Abstract To ascertain the effectiveness of slacklining as a supplementary therapy for elderly stroke patients who are functionally non-progressing. This case study involved an 18-mo prospective observation of the management of an 87-year-old female stroke-patient of the left hemisphere with reduced balance, reduced lower limb muscular activation, hypertonia, and concurrent postural deficits. This entailed the initial acute care phase through to discharge to home and 18-mo final status in her original independent living setting. The introduction of slacklining as an adjunct thera...
Source: World Journal of Orthopaedics - September 15, 2016 Category: Orthopaedics Tags: World J Orthop Source Type: research

Effects of thalamic hemorrhagic lesions on explicit and implicit learning during the acquisition and retrieval phases in an animal model of central post-stroke pain.
Abstract Hemorrhagic stroke has many symptoms, including central pain, learning and memory impairments, motor deficits, language problems, emotional disturbances, and social maladjustment. Lesions of the ventral basal complex (VBC) of the thalamus elicit thermal and mechanical hyperalgesia, forming an animal model of central post-stroke pain (CPSP). However, no research has yet examined the involvement of learning and memory in CPSP using an animal model. The present study examined whether VBC lesions affect motor function, conditioned place preference (CPP; implicit memory), and spatial learning (explicit memory)...
Source: Behavioural Brain Research - September 24, 2016 Category: Neurology Authors: Wang CC, Shih HC, Shyu BC, Huang AC Tags: Behav Brain Res Source Type: research

Sensors, Vol. 16, Pages 1631: Assessing Walking Strategies Using Insole Pressure Sensors for Stroke Survivors
Insole pressure sensors capture the different forces exercised over the different parts of the sole when performing tasks standing up such as walking. Using data analysis and machine learning techniques, common patterns and strategies from different users to achieve different tasks can be automatically extracted. In this paper, we present the results obtained for the automatic detection of different strategies used by stroke survivors when walking as integrated into an Information Communication Technology (ICT) enhanced Personalised Self-Management Rehabilitation System (PSMrS) for stroke rehabilitation. Fourteen stroke su...
Source: Sensors - September 30, 2016 Category: Biotechnology Authors: Mario Munoz-Organero Jack Parker Lauren Powell Susan Mawson Tags: Article Source Type: research

Association between genetic variation in the dopamine system and motor recovery after stroke.
CONCLUSION: These data suggest that genetic variation of dopamine-related genes may affect motor recovery after stroke and that COMT polymorphism could be useful for predicting motor recovery. PMID: 27689550 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - October 2, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

A new approach to distinguish migraine from stroke by mining structured and unstructured clinical data-sources
In this study, we utilized text and data mining methods to extract the most important predictors from clinical reports in order to establish a migraine detection model and distinguish migraine patients from stroke or other types of mimic (non-stroke) cases. The available data for this study was a heterogeneous mix of free-text fields, such as triage main-complaints and specialist final-impressions, as well as numeric data about patients, such as age, blood-pressure, and so on. After a careful combination of these sources, we obtained a highly imbalanced dataset where the migraine cases were only about 6  % of the dataset....
Source: Network Modeling Analysis in Health Informatics and Bioinformatics - October 5, 2016 Category: Bioinformatics Source Type: research

Mayo Clinic Minute: Get the facts on stroke
Someone in the U.S. has a stroke every 40 seconds. The good news is that strokes can be treated and prevented, and many fewer Americans die of stroke now than even 15 years ago.Today,?World Stroke Day,?learn the?warning signs,?and respond quickly if you believe?someone is?suffering a stroke. As Vivien Williams explains in this Mayo Clinic Minute, [...]
Source: News from Mayo Clinic - October 28, 2016 Category: Databases & Libraries Source Type: news

Influence of skill and exercise training parameters on locomotor recovery during stroke rehabilitation
Purpose of review: Research findings from the fields of motor learning and exercise physiology suggest specific training parameters that can be manipulated during physical rehabilitation profoundly influence skilled task performance. This review details the rationale for some of these training variables and their application in selected intervention studies focused on improving walking function in patients poststroke. Recent findings: Basic and applied studies have shown that the amount, intensity, and variability of specific task practice applied during rehabilitation interventions can affect recovery of walking poststro...
Source: Current Opinion in Neurology - November 8, 2016 Category: Neurology Tags: TRAUMA AND REHABILITATION: Edited by Bruce H. Dobkin Source Type: research

Personalized and parametrized AVATAR for interacting with post-stroke action-perception loop during rehabilitation
Discussion – conclusion Using increased avatar allows to interfere with the action-perception loop, and make healthy and affected subjects bend their knee more than usual. We expect mirror neuron system to be involved in this spontaneous imitation mechanism. Experimentation dedicated to brain afferents is considered using an electroencephalogram to determine an optimum angle with stroke patients to generalize use of enhanced feedback during rehabilitation.
Source: Neurophysiologie Clinique - November 7, 2016 Category: Neuroscience Source Type: research

The acute complications of melas: a case series
Mitochondrial cytopathies are maternally inherited disorders of ATP production, with a predilection for primarily affecting the CNS. Many clinical phenotypes exist, each with varying involvement of skeletal and cardiac muscles, the kidneys and gastrointestinal system. Mitochondrial cytopathies can present early in life, but increasingly neurologists are faced with acute presentations of mitochondrial disease in adulthood. MELAS (mitochondrial encephalopathy, lactic acidosis and stroke-like syndrome) is a mitochondrial disorder that can present both insidiously and acutely. Common acute features are encephalopathy, seizures...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Bramhall, N., Jones, M. Tags: Epilepsy and seizures, Stroke, Psychotic disorders (incl schizophrenia) ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Analysis of Balance during Functional Walking in Stroke Survivors
DiscussionWe developed and demonstrated a method to assess walking balance of stroke survivors. System design and evaluation methods allow balance evaluation during functional walking in daily life. Some presented metrics show correlations with BBS scores. Clear inter- and intra-patient variations in metric values are present that cannot be explained by BBS scores, which supports the additional value of the presented system. Presented methods may be used for objective evaluation of restitution and compensation of walking balance and have a potential application in individual evidence-based therapy.
Source: PLoS One - November 16, 2016 Category: Biomedical Science Authors: Fokke B. van Meulen Source Type: research

“Are you going to come and see us again soon?” An intergenerational event between stroke survivors and school-children
Quality in Ageing and Older Adults,Volume 17, Issue 4, Page 246-252, December 2016. Purpose A one-hour intergenerational event held at an infant school in Norfolk, England, aimed to increase the citizenship experience of young children and their awareness of what it means to live with stroke, and to address social isolation or self-confidence in communicating among stroke survivors with aphasia. It was also intended to gauge whether this activity might provide a basis for future research. The paper aims to discuss these issues. Design/methodology/approach Four community-dwelling stroke survivors with aphasia were recruited...
Source: Quality in Ageing and Older Adults - November 22, 2016 Category: Geriatrics Source Type: research

Medical News Today: Stroke vs. Aneurysm: Treatment Options
What is a brain aneurysm? Learn about the different types of strokes and brain aneurysms as well as the treatment options available for both.
Source: Health News from Medical News Today - November 25, 2016 Category: Consumer Health News Tags: Stroke Source Type: news

Increased functional connectivity one week after motor learning and tDCS in stroke patients
Publication date: 6 January 2017 Source:Neuroscience, Volume 340 Author(s): Stéphanie Lefebvre, Laurence Dricot, Patrice Laloux, Philippe Desfontaines, Frédéric Evrard, André Peeters, Jacques Jamart, Yves Vandermeeren Recent studies using resting-state functional magnetic resonance imaging (rs-fMRI) demonstrated that changes in functional connectivity (FC) after stroke correlate with recovery. The aim of this study was to explore whether combining motor learning to dual transcranial direct current stimulation (dual-tDCS, applied over both primary motor cortices (M1)) modulated FC in stroke patients. Twenty-two chronic...
Source: Neuroscience - November 25, 2016 Category: Neuroscience Source Type: research

Biofeedback improves performance in lower limb activities more than usual therapy in people following stroke: a systematic review
Conclusion: Biofeedback is more effective than usual therapy in improving performance of activities. Further research is required to determine the long-term effect on learning. Given that many biofeedback machines are relatively inexpensive, biofeedback could be utilised widely in clinical practice. [Stanton R, Ada L, Dean CM, Preston E (2016) Biofeedback improves performance in lower limb activities more than usual therapy in people following stroke: a systematic review. Journal of Physiotherapy XX: XX-XX]
Source: Journal of Physiotherapy - November 25, 2016 Category: Physiotherapy Source Type: research

Stroke Risk Stratification and its Validation using Ultrasonic Echolucent Carotid Wall Plaque Morphology: A Machine Learning Paradigm
Stroke risk stratification based on grayscale morphology of the ultrasound carotid wall has recently been shown to have a promise in classification of high risk versus low risk plaque or symptomatic versus asymptomatic plaques. In previous studies, this stratification has been mainly based on analysis of the far wall of the carotid artery. Due to the multifocal nature of atherosclerotic disease, the plaque growth is not restricted to the far wall alone. This paper presents a new approach for stroke risk assessment by integrating assessment of both the near and far walls of the carotid artery using grayscale morphology of the plaque.
Source: Computers in Biology and Medicine - November 25, 2016 Category: Bioinformatics Authors: Tadashi Araki, Pankaj K. Jain, Harman S. Suri, Narendra D. Londhe, Nobutaka Ikeda, Ayman El-Baz, Vimal K. Shrivastava, Luca Saba, Andrew Nicolaides, Shoaib Shafique, John R. Laird, Ajay Gupta, Jasjit S. Suri Source Type: research

“Are you going to come and see us again soon?” An intergenerational event between stroke survivors and school-children
Quality in Ageing and Older Adults,Volume 17, Issue 4, Page 246-252, December 2016. Purpose A one-hour intergenerational event held at an infant school in Norfolk, England, aimed to increase the citizenship experience of young children and their awareness of what it means to live with stroke, and to address social isolation or self-confidence in communicating among stroke survivors with aphasia. It was also intended to gauge whether this activity might provide a basis for future research. The paper aims to discuss these issues. Design/methodology/approach Four community-dwelling stroke survivors with aphasia were recruited...
Source: Quality in Ageing and Older Adults - November 22, 2016 Category: Geriatrics Source Type: research

Prehospital Ultrasound Proves its Worth in the War Against Stroke
Discussion Stroke is a devastating neurologic condition with an alarming prevalence. Each year, an estimated 795,000 people in the United States alone will suffer a stroke. Stroke accounts for one in every 20 deaths in the U.S., and someone dies of stroke in the U.S. every four minutes.1 One third of people who have had a stroke will be left with some degree of long-term disability.2 Eighty-seven percent of all strokes are ischemic, meaning that a clot or other occlusion to blood flow forms within an intracranial vessel, depriving the brain tissue of blood flow.1 If this obstruction isn't rapidly relieved, damage to the brain will occur.
Source: JEMS Patient Care - December 1, 2016 Category: Emergency Medicine Authors: Jenna M. B. White, MD Tags: Patient Care Source Type: news

Explicit motor sequence learning with the paretic arm after stroke.
CONCLUSIONS: Stroke survivors can learn a movement sequence with their paretic arm, but demonstrate impairments in sequence specific learning. Implications for Rehabilitation Motor sequence learning is important for recovery of movement after stroke. Stroke survivors were found to be capable of learning a movement sequence with their paretic arm, supporting the concept of repetitive task training for recovery of movement. Stroke survivors showed impaired sequence specific learning in comparison with age-matched controls, indicating that they may need more repetitions of a sequence in order to re-learn movements. Further re...
Source: Disability and Rehabilitation - December 6, 2016 Category: Rehabilitation Authors: Fleming MK, Newham DJ, Rothwell JC Tags: Disabil Rehabil Source Type: research

Predicting Motor Sequence Learning in Individuals With Chronic Stroke
Conclusion. Nonlinear information extracted from multiple time points across practice, specifically the rate of motor skill acquisition during practice, relates strongly with changes in motor behavior at the retention test following practice and could be used to predict optimal doses of practice on an individual basis.
Source: Neurorehabilitation and Neural Repair - December 10, 2016 Category: Neurology Authors: Wadden, K. P., Asis, K. D., Mang, C. S., Neva, J. L., Peters, S., Lakhani, B., Boyd, L. A. Tags: Original Research Articles Source Type: research

Can Motor Recovery in Stroke Be Improved by Non-invasive Brain Stimulation?
Authors: Rothwell JC Abstract At the present time, there is enormous interest in methods of non-invasive brain stimulation. These interact with ongoing neural activity, mainly in cerebral cortex, and have measureable effects on behaviours in healthy people. More intriguingly, they appear to have effects on synaptic plasticity that persist even after stimulation has ceased. This has led, as might be expected, to the proposal that brain stimulation methods might be therapeutically useful in rehabilitation. The rationale is that physical therapy involves learning new patterns of activity to compensate for those lost t...
Source: Advances in Experimental Medicine and Biology - January 1, 2017 Category: Research Tags: Adv Exp Med Biol Source Type: research