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Abstract 219: Interdisciplinary Education and Relationship Building Improve Communication and Coordination in Stroke Care Session Title: Poster Session II
Conclusion: Through providing education to EMS providers and building relationships between EMS and hospitals, there has been a significant increase in pre-notification by EMS therefore improving timeliness of CT scans in acute stroke patients.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Thorson, S., Sather, J., Alexander, J., Cook, M. Tags: Session Title: Poster Session II Source Type: research

Superhero Joey: Five-year-old fights moyamoya disease
It’s been said that not all heroes wear capes — but Joey Gallagher owns several. The five-year-old has already amassed a collection of superhero gear, from a Superman Halloween costume to a t-shirt emblazoned with the Batman logo. Yet even the most diehard comic book fan would likely admit that feats like flying, leaping tall buildings and fighting bad guys don’t hold a candle to the challenges this little boy has already surmounted. Just last June, Joey was out of town with his family when he had what his parents, Leila and Scott, feared was a seizure. Clinicians in the emergency department dismissed the event as he...
Source: Thrive, Children's Hospital Boston - April 4, 2017 Category: Pediatrics Authors: Jessica Cerretani Tags: Diseases & Conditions Our Patients’ Stories childhood stroke Dr. Edward Smith Dr. Michael Scott moyamoya Moyamoya Disease Program Source Type: news

The effect of transcranial direct current stimulation on motor sequence learning and upper limb function after stroke.
CONCLUSIONS: Unilateral tDCS is effective for improving JTT performance, but not motor sequence learning. SIGNIFICANCE: This has implications for the design of future clinical trials. PMID: 28410884 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - March 31, 2017 Category: Neurology Authors: Fleming MK, Rothwell JC, Sztriha L, Teo JT, Newham DJ Tags: Clin Neurophysiol Source Type: research

Use of Machine Learning Classifiers and Sensor Data to Detect Neurological Deficit in Stroke Patients
Conclusions: Sensors and machine learning methods can reliably detect stroke signs and quantify proximal arm weakness. Our proposed solution will facilitate pervasive monitoring of stroke patients.
Source: Journal of Medical Internet Research - April 18, 2017 Category: Journals (General) Authors: Eunjeong Park Hyuk-Jae Chang Hyo Suk Nam Source Type: research

Supporting Stroke Motor Recovery Through a Mobile Application: A Pilot Study.
Abstract Neuroplasticity and motor learning are promoted with repetitive movement, appropriate challenge, and performance feedback. ARMStrokes, a smartphone application, incorporates these qualities to support motor recovery. Engaging exercises are easily accessible for improved compliance. In a multiple-case, mixed-methods pilot study, the potential of this technology for stroke motor recovery was examined. Exercises calibrated to the participant's skill level targeted forearm, elbow, and shoulder motions for a 6-wk protocol. Visual, auditory, and vibration feedback promoted self-assessment. Pre- and posttest dat...
Source: The American Journal of Occupational Therapy - April 21, 2017 Category: Occupational Health Authors: Lawson S, Tang Z, Feng J Tags: Am J Occup Ther Source Type: research

Overrepresentation of isolated verbal repetition deficits in aphasic males with stroke: A systematic literature review and meta-analysis (P4.211)
Conclusions:Chronic isolated repetition deficits are more prevalent in men than in women. This finding is clinically relevant because of repetition’s role in language acquisition and recovery, being a main mechanism by which children learn to speak and a major resource in language rehabilitation techniques.Disclosure: Dr. Pertierra has nothing to disclose. Dr. Torres Prioris has nothing to disclose. Dr. Dávila has nothing to disclose. Dr. Allegri has nothing to disclose. Dr. Berthier has received personal compensation for activities with Pfizer/Eisai, Merz, Lundbeck, GlaxoSmithKline, Eli Lilly, Novartis and Ja...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pertierra, L., Prioris, M. J. T., Davila, M. G., Allegri, R., Torres, M. B. Tags: Behavioral and Cognitive Neurology: Language Source Type: research

1 in 3 Americans May Have Had Warning Stroke without Knowing It
Study authors say learn the signs and symptoms that mean you need immediate medical help Source: HealthDay Related MedlinePlus Pages: Stroke, Transient Ischemic Attack
Source: MedlinePlus Health News - May 1, 2017 Category: Consumer Health News Source Type: news

Effect of stroke-order learning and handwriting exercises on recognizing and writing Chinese characters by Chinese as a foreign language learners
This study used a computer-based teaching system to investigate the effectiveness of stroke-order learning and writing exercises in promoting the ability of Chinese-as-a-foreign-language (CFL) learners to recognize and write Chinese characters. This study included a 2 (stroke-order and non-stroke-order) × 2 (writing exercise and non-writing exercise) × 2 (test point) mixed factorial design involving a total of 91 participants. We compared the difference in their Chinese character learning, including Chinese character recognition and handwriting, based on the learning conditions. We found that CFL learners who practic...
Source: Computers in Human Behavior - May 3, 2017 Category: Information Technology Source Type: research

Shaping innovations in long-term care for stroke survivors with multimorbidity through stakeholder engagement
ConclusionsStakeholder engagement to identify data-driven solutions is feasible but requires resources. While a number of potential interventions were identified, the final choice rested not just on stakeholder priorities but also on data availability. Further work is required to evaluate the impact and implementation of data-driven interventions for long-term stroke survivors.
Source: PLoS One - May 5, 2017 Category: Biomedical Science Authors: Euan Sadler Source Type: research

Brain volume loss precedes cognitive decline in the first year after ischaemic stroke
Conclusions Brain volume loss precedes cognitive decline in the first year after ischaemic stroke. Tracking brain volume after stroke is important because brain volume is predictive of cognitive decline and atrophy is a hallmark of dementia.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 8, 2017 Category: Neurosurgery Authors: Werden, E., Cumming, T., Bird, L., Khlif, M., Brodtmann, A. Tags: Abstracts Source Type: research

Non-Vitamin K Oral Anticoagulants for Stroke Prevention in Special Populations with Atrial Fibrillation
AbstractAtrial fibrillation (AF) is associated with an increased risk of ischemic stroke or systemic embolism compared with normal sinus rhythm. These strokes may efficiently be prevented in patients with risk factors using oral anticoagulant therapy, with either vitamin K antagonists (VKAs) or non-vitamin K antagonist oral anticoagulants (NOACs) (i.e., direct thrombin inhibitors or direct factor Xa inhibitors). Owing to their specific risk profiles, some AF populations may have increased risks of both thromboembolic and bleeding events. These AF patients may be denied oral anticoagulants, whilst evidence shows that the ab...
Source: Advances in Therapy - May 10, 2017 Category: Drugs & Pharmacology Source Type: research

Effects of Rat Anti-mouse Interleukin-6 Receptor Antibody on the Recovery of Cognitive Function in Stroke Mice.
This study aimed to investigate the effects of rat anti-mouse interleukin (IL)-6 receptor antibody (MR16-1) on the recovery of cognitive function in stroke mice. Adult male C57BL/6 mice were subjected to middle cerebral artery occlusion (MCAO). Mice were randomly assigned into three groups: sham group, model group, and MR16-1 group. After the treatment of MR16-1, spatial learning and memory performance of mice were evaluated by the Morris water maze (MWM) and Y-maze tests. Then, brain slices were obtained and infarct volume and neuronal apoptosis were assessed by 2,3,5-triphenyltetrazolium chloride (TTC) staining and Termi...
Source: Cellular and Molecular Neurobiology - May 9, 2017 Category: Cytology Authors: Wei J, Sun C, Liu C, Zhang Q Tags: Cell Mol Neurobiol Source Type: research

Plaque Tissue Morphology-Based Stroke Risk Stratification Using Carotid Ultrasound: A Polling-Based PCA Learning Paradigm
AbstractSevere atherosclerosis disease in carotid arteries causes stenosis which in turn leads to stroke. Machine learning systems have been previously developed for plaque wall risk assessment using morphology-based characterization. The fundamental assumption in such systems is the extraction of the grayscale features of the plaque region. Even though these systems have the ability to perform risk stratification, they lack the ability to achieve higher performance due their inability to select and retain dominant features. This paper introduces a polling-based principal component analysis (PCA) strategy embedded in the m...
Source: Journal of Medical Systems - May 13, 2017 Category: Information Technology Source Type: research

Lori’s Stroke Required Help From Doctors An Hour Away. Telemedicine Provided It.
Editor’s note: Our previous stories this American Stroke Month featured warning signs heeded and missed. Today we shift gears to showcase a textbook response to a stroke, including the crucial role of telestroke, a way for experts at another facility to help care for a patient via a webcam-type connection. The CHRONIC Care Act, which includes a provision to require Medicare to cover telestroke, will be discussed Tuesday during a hearing of the Senate Finance Committee. Lori Hoopingarner savored her occasional weekend getaway. Between running her financial advising company, raising a 10-year-old daughter and 6-year-old s...
Source: Healthy Living - The Huffington Post - May 15, 2017 Category: Consumer Health News Source Type: news

Transcranial direct current stimulation combined with visuo-motor training as treatment for chronic stroke patients.
CONCLUSION: Four-week visuo-motor training combined with tDCS showed no difference between the Active and Sham groups in the total UE FMA score, which may be explained by heterogeneity of the degree of recovery in the Active group. However, the shoulder-elbow FMA sub-score improved significantly more in the Active compared to the Sham group, which deserves further study. PMID: 28506002 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - May 17, 2017 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Keeping up with Amanda: Life after brain surgery
In most ways, Amanda LePage is just like any other rambunctious fourth grader. She loves school, dance class, playing basketball and keeping up with her twin sister Macy and older brother Nathan. Sometimes it just takes her a little longer to do these everyday things. That’s because Amanda has been through a lot in her short nine years. Amanda was just 5 months old when she was brought by helicopter to Boston Children’s Hospital for a hemorrhage in her brain from an intracranial aneurysm, a type of vascular malformation. Despite long odds, Amanda survived two life-saving brain surgeries and a massive stroke that left ...
Source: Thrive, Children's Hospital Boston - May 22, 2017 Category: Pediatrics Authors: Ellen Greenlaw Tags: Our Patients’ Stories brain aneurysm Dr. Caroline Robson Dr. Craig McClain Dr. Edward Smith Dr. Peter Manley Hydrocephalus low-grade glioma pediatric stroke Source Type: news

Genetic Variation and Neuroplasticity: Role in Rehabilitation After Stroke.
Abstract BACKGROUND AND PURPOSE: In many neurologic diagnoses, significant interindividual variability exists in the outcomes of rehabilitation. One factor that may impact response to rehabilitation interventions is genetic variation. Genetic variation refers to the presence of differences in the DNA sequence among individuals in a population. Genetic polymorphisms are variations that occur relatively commonly and, while not disease-causing, can impact the function of biological systems. The purpose of this article is to describe genetic polymorphisms that may impact neuroplasticity, motor learning, and recovery a...
Source: Physical Therapy - June 20, 2017 Category: Physiotherapy Authors: Stewart JC, Cramer SC Tags: J Neurol Phys Ther Source Type: research

Domain-general subregions of the medial prefrontal cortex contribute to recovery of language after stroke
AbstractWe hypothesized that the recovery of speech production after left hemisphere stroke not only depends on the integrity of language-specialized brain systems, but also on ‘domain-general’ brain systems that have much broader functional roles. The presupplementary motor area/dorsal anterior cingulate forms part of the cingular-opercular network, which has a broad role in cognition and learning. Consequently, we have previously suggested that variability in the rec overy of speech production after aphasic stroke may relate in part to differences in patients’ abilities to engage this domain-general brain region. T...
Source: Brain - June 27, 2017 Category: Neurology Source Type: research

Effect of Visual Art School–Based Stroke Intervention for Middle School Students
ABSTRACT: Background: Community stroke awareness initiatives have traditionally been used to expand knowledge of stroke signs and risk factors to high-risk adult populations. Here, we use a novel unfettered, visual art–based approach for an elementary school initiative to raise stroke awareness. Methods: Seventh graders in a middle school art class received stroke awareness training during the course of the 2015 to 2016 school year through their teacher in the visual arts class. In turn, they used this training to develop their own artistic interpretations of key stroke awareness concepts via project-based learning and t...
Source: Journal of Neuroscience Nursing - June 30, 2017 Category: Neuroscience Tags: Article Source Type: research

Predicting ischemic stroke after carotid artery stenting based on proximal calcification and the jellyfish sign.
CONCLUSIONS The jellyfish sign, proximal Ca, and LDL cholesterol were considered to be important predictors for new DWI lesions after CAS. These 3 factors can be easily determined during a standard clinical visit. Thus, these 3 variables-especially the jellyfish sign and proximal Ca-may be useful for reducing the ischemic stroke risk in patients with stenosis of the cervical carotid artery. PMID: 28686117 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - July 7, 2017 Category: Neurosurgery Authors: Ichinose N, Hama S, Tsuji T, Soh Z, Hayashi H, Kiura Y, Sakamoto S, Okazaki T, Ishii D, Shinagawa K, Kurisu K Tags: J Neurosurg Source Type: research

BDNF Val66Met but not transcranial direct current stimulation affects motor learning after stroke
Conclusion BDNF Val66Met is a determinant of motor skill learning after stroke and could be important for prognostic models. tDCS does not modulate motor skill learning in our study and might be less effective than previously assumed.
Source: Brain Stimulation - July 13, 2017 Category: Neurology Source Type: research

Transcranial Direct Current Stimulation Improves Audioverbal Memory in Stroke Patients
Objective: The aim of this study was to investigate whether anodal transcranial direct current stimulation over the left temporoparietal area improved audioverbal memory performance in stroke patients. Design: Twelve stroke patients with audioverbal memory impairment participated in a single-masked, crossover, and sham-controlled experiment. The anodal or sham transcranial direct current stimulation was applied during the Rey Auditory Verbal Learning Test, which evaluates the ability to recall a list of 15 heard words over five trials. The number of correctly recalled words was compared between the anodal and sham conditi...
Source: American Journal of Physical Medicine and Rehabilitation - July 19, 2017 Category: Rehabilitation Tags: Original Research Articles Source Type: research

' Smart ' Robot Technology Could Give Stroke Rehab a Boost
WEDNESDAY, July 19, 2017 -- Scientists say they have developed a " smart " robotic harness that might make it easier for people to learn to walk again after a stroke or spinal cord injury. The harness, the researchers said, can be fine-tuned to...
Source: Drugs.com - Daily MedNews - July 19, 2017 Category: General Medicine Source Type: news

Research Articles A multidirectional gravity-assist algorithm that enhances locomotor control in patients with stroke or spinal cord injury
Gait recovery after neurological disorders requires remastering the interplay between body mechanics and gravitational forces. Despite the importance of gravity-dependent gait interactions and active participation for promoting this learning, these essential components of gait rehabilitation have received comparatively little attention. To address these issues, we developed an adaptive algorithm that personalizes multidirectional forces applied to the trunk based on patient-specific motor deficits. Implementation of this algorithm in a robotic interface reestablished gait dynamics during highly participative locomotion wit...
Source: Science Translational Medicine - July 19, 2017 Category: Biomedical Science Authors: Mignardot, J.-B., Le Goff, C. G., van den Brand, R., Capogrosso, M., Fumeaux, N., Vallery, H., Anil, S., Lanini, J., Fodor, I., Eberle, G., Ijspeert, A., Schurch, B., Curt, A., Carda, S., Bloch, J., von Zitzewitz, J., Courtine, G. Tags: Research Articles Source Type: research

Comprehensive Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attack or Mild Stroke: PSYCHOLOGICAL PROFILE AND OUTCOMES.
CONCLUSIONS: Anxiety and executive dysfunction persisted post-TIA/MNDS. Although promising for secondary prevention post-TIA/MNDS, CCR was not independently associated with psychological improvements. CCR psychological treatment may benefit depression. Subacute NYHA class and depression may later affect quality of life. PMID: 28727668 [PubMed - as supplied by publisher]
Source: Journal of Cardiopulmonary Rehabilitation and Prevention - July 19, 2017 Category: Rehabilitation Authors: Prior PL, Hachinski V, Chan R, Unsworth K, Mytka S, Harnadek M, OʼCallaghan C, Suskin N Tags: J Cardiopulm Rehabil Prev Source Type: research

Integrated Machine Learning Approaches for Predicting Ischemic Stroke and Thromboembolism in Atrial Fibrillation.
In this study, we used integrated machine learning and data mining approaches to build 2-year TE prediction models for AF from Chinese Atrial Fibrillation Registry data. We first performed data cleansing and imputation on the raw data to generate available dataset. Then a series of feature construction and selection methods were used to identify predictive risk factors, based on which supervised learning methods were applied to build the prediction models. The experimental results show that our approach can achieve higher prediction performance (AUC: 0.71~0.74) than previous TE prediction models for AF (AUC: 0.66~0.69), an...
Source: AMIA Annual Symposium Proceedings - August 8, 2017 Category: Bioinformatics Tags: AMIA Annu Symp Proc Source Type: research

Cardiovascular Medical History Drives Risk of Ischemic Stroke in LVAD Patients
Purpose: The risk of stroke continues to be a major adverse event post-LVAD implantation, limiting the utility of LVADs in the less-sick patient population. Between 2010 and 2015 there were 4,185 neurologic events and 1104 were due to ischemic stroke. Of these, 16% were fatal. The goal of our study was to explore the myriad factors driving risk for ischemic stroke, based on the condition of the patient pre-implant. We use a Bayesian Network machine-learning approach, which allows for studying complex variable correlations.
Source: Journal of Cardiac Failure - August 1, 2017 Category: Cardiology Authors: Lisa C. Lohmueller, Carmen Khoo, James F. Antaki Source Type: research

Reported use of technology in stroke rehabilitation by physical and occupational therapists.
CONCLUSIONS: The use of technology is not pervasive in the continuum of stroke rehabilitation. Implications for Rehabilitation The patient care experience is a priority in healthcare, so when patients report feeling bored and desiring greater fostering of autonomy in stroke rehabilitation, it is troubling. Research examining the use of technology has shown positive results for improving motor performance and engaging patients through entertainment and use of objective feedback. Physical and occupational therapists do not widely use technology in stroke rehabilitation. Therapists should consider using technology in stroke r...
Source: Disability and Rehabilitation. Assistive Technology. - August 16, 2017 Category: Rehabilitation Authors: Langan J, Subryan H, Nwogu I, Cavuoto L Tags: Disabil Rehabil Assist Technol Source Type: research

The robotics helping stroke patients regain balance
Re-learning how to walk normally is an essential part of rehabilitation, especially for patients who have suffered a stroke. In Slovenia, the University Rehabilitation Institute in Ljubljana is testing a unique robot that not only helps people to walk again but also to regain a sense of balance.
Source: EUROPA - Research Information Centre - August 21, 2017 Category: Research Source Type: news

Beneficial Effects of Delayed P7C3-A20 Treatment After Transient MCAO in Rats
AbstractDespite ischemic stroke being the fifth leading cause of death in the USA, there are few therapeutic options available. We recently showed that the neuroprotective compound P7C3-A20 reduced brain atrophy, increased neurogenesis, and improved functional recovery when treatment was initiated immediately post-reperfusion after a 90-min middle cerebral artery occlusion (MCAO). In the present study, we investigated a more clinically relevant therapeutic window for P7C3-A20 treatment after ischemic stroke. MCAO rats were administered P7C3-A20 for 1  week, beginning immediately or at a delayed point, 6 h post-reperfusio...
Source: Translational Stroke Research - August 25, 2017 Category: Neurology Source Type: research

Acute ischemic stroke what is hidden behind?
We present a case of a 58-year-old male patient that presented to ED with sudden onset of headache and left-sided hemiparesis, computed tomography (CT) demonstrated an ischemic stroke of the right middle cerebral artery. When the question of whether to start r-TPA or mechanical thrombectomy was discussed, a cardiac point-of-care ultrasound was performed in ED and showed a type A aortic dissection; immediately a CT aortic angiogram was performed and confirmed the diagnosis. The patient was taken to theater and had a favorable outcome. <Learning objective: Acute aortic dissection (AAD) may present as acute ischemic st...
Source: Journal of Cardiology Cases - August 31, 2017 Category: Cardiology Source Type: research

Time-resolved CT assessment of collaterals as imaging biomarkers to predict clinical outcomes in acute ischemic stroke
ConclusionOur data results reinforce the importance of careful patient selection for recanalization therapy to avoid futile recanalization. The paucity of collaterals predicts poor clinical outcome despite recanalization. On the other hand, robust collaterals warrant consideration for recanalization therapy given the better odds of good clinical outcome.
Source: Neuroradiology - September 1, 2017 Category: Radiology Source Type: research

Stroke-associated pattern of gene expression previously identified by machine-learning is diagnostically robust in an independent patient population
The objective of this study was to assess the diagnostic capacity and temporal stability of this stroke-associated transcriptional signature in an independent patient population. Publicly available whole blood microarray data generated from 23 ischemic stroke patients at 3, 5, and 24h post-symptom onset, as well from 23 cardiovascular disease controls, were obtained via the National Center for Biotechnology Information Gene Expression Omnibus. Expression levels of the ten candidate genes (ANTXR2, STK3, PDK4, CD163, MAL, GRAP, ID3, CTSZ, KIF1B, and PLXDC2) were extracted, compared between groups, and evaluated for their dis...
Source: Genomics Data - September 2, 2017 Category: Genetics & Stem Cells Source Type: research

Best practice interprofessional stroke care collaboration and simulation: The student perspective.
Authors: MacKenzie D, Creaser G, Sponagle K, Gubitz G, MacDougall P, Blacquiere D, Miller S, Sarty G Abstract Interprofessional practice (IPP) is the accepted standard of care for clients following a stroke. A brief, embedded and evidence-based IPP team simulation was designed to address stroke care knowledge and IPP competencies for students within limited curriculum space. Each team was required to construct a collaborative care plan for their patient during the simulation and submit the care plan for evaluation of best practice stroke care knowledge and implementation with evidence of interprofessional collabora...
Source: Journal of Interprofessional Care - September 3, 2017 Category: Health Management Tags: J Interprof Care Source Type: research

Athletes at risk: Knowing the dangers of heat stroke
For many young athletes, fall sports practices have already started. Whether it’s football two-a-days, soccer practices on a sweltering turf field, or cross country training in the late summer sun, the threat of heat exhaustion and heat stroke is prevalent across all sports. It’s an important time for athletes and parents to be aware of the signs of heat illnesses, especially given that children and adolescents are more susceptible to heat stroke than adults. Younger athletes produce more heat during activity, sweat less, and adjust less rapidly to changes in environmental heat. Certain sports also carry unique risks f...
Source: Thrive, Children's Hospital Boston - September 5, 2017 Category: Pediatrics Authors: Connor Ertz Tags: Ask the Expert Division of Sports Medicine Dr. Michael Beasley football heat exposure Source Type: news

Changes in spectroscopic biomarkers after transcranial direct current stimulation in children with perinatal stroke
Conclusions MRS metabolite levels and changes may reflect mechanisms of tDCS-related M1 plasticity and response biomarkers in hemiparetic children with perinatal stroke undergoing intensive neurorehabilitation.
Source: Brain Stimulation - September 13, 2017 Category: Neurology Source Type: research

Device used to close small hole in heart may protect against recurrent stroke
A device used to close a small hole in the heart may benefit certain stroke patients by providing an extra layer of protection for those facing years of ongoing stroke risk, according to the results of a large clinical trial led by UCLA researchers.“It is a major new treatment option for some people,” said Dr. Jeffrey Saver, director of theUCLA Comprehensive Stroke Center and lead author of the study. However, he added, “Using the device is going to have to be a considered clinical decision between the doctor and the patient about who’s the right person to get it.”Thefindings appear in the Sept. 14 New England Jo...
Source: UCLA Newsroom: Health Sciences - September 14, 2017 Category: Universities & Medical Training Source Type: news

A nearly full-recovery from AVM hemorrhagic stroke 17 years after insult using a new integrated neurodevelopmental approach: A case report
This study investigated a novel approach to chronic-phase stroke rehabilitation using traditional child motor-learning techniques, play, and proprioceptive-building activities in addition to current stroke rehabilitation techniques. During an initial six-month period, followed by a three-year period, the participant used motor-developmental learning activities as well as traditional strength, gait, and balance training. During the initial phase of treatment, clinically-significant improvements were recorded along with self-reported lifestyle enhancements. These gains continued throughout the three-and-a-half year process. ...
Source: Medicine - September 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Combining Robotic & Assistive Technologies To Improve Outcomes: A Pilot Study Quantifying Stroke Rehabilitation
Stroke is the leading causes of long-term disability in the United States. Unfortunately, many survivors experience upper extremity (UE) impairment with few rehabilitation opportunities, secondary to a lack of voluntary muscle control. We developed a novel UE rehabilitation paradigm (TDS-HM) that uses a Tongue Drive System (TDS) to control a robotic device (HandMentor: HM), encouraging active learning through a game-like user interface. We hypothesize TDS-HM training will improve motor performance, reduce UE impairment, and improve quality of life in stroke survivors.
Source: Archives of Physical Medicine and Rehabilitation - September 24, 2017 Category: Rehabilitation Authors: Stephen Housley, David Wu, Kimberly Richards, Samir Belagaje, Maysam Ghovanloo, Andrew Butler Source Type: research

Transfer of Robotic Therapy to Daily Activities After Stroke: Considerations for Patient-Targeted Home Programs
To develop and refine a stroke therapy protocol that combines robotic therapy with patient-targeted home programs based on motor learning principles. To describe intervention effects on paretic upper limb function and activity performance via outcome measures across ICF domains. To examine pilot study strengths and limitations in preparation for planning a larger clinical trial.
Source: Archives of Physical Medicine and Rehabilitation - September 24, 2017 Category: Rehabilitation Authors: Susan Fasoli Source Type: research

Timing independent spatial motor sequence learning is preserved in left hemisphere stroke
Publication date: Available online 28 September 2017 Source:Neuropsychologia Author(s): Anna Dovern, Eva Niessen, Jana M. Ant, Jochen Saliger, Hans Karbe, Gereon R. Fink, Iring Koch, Peter H. Weiss During neurorehabilitation, the re-learning of motor sequences is crucial for patients with motor deficits, enabling them to master again complex movements. A recent study showed that patients with left hemisphere (LH) stroke exhibited preserved motor sequence learning (as assessed by the serial reaction time (SRT) task) when the timing of the stimuli was comparable in the training and later test phase. However, patients showed...
Source: Neuropsychologia - September 28, 2017 Category: Neurology Source Type: research

UCLA Health launches pioneering mobile stroke unit with support from L.A. County
Roughly every 40 seconds, someone in the United States will have a stroke. Almost every four minutes, one of those people will die as a result. Against that backdrop, UCLA Health has officially launched the first mobile stroke unit on the West Coast, enabling rapid delivery of brain-saving medications to stroke patients who might otherwise face debilitating delays in treatment.  As part of the first phase of a pilot program, the specialized ambulance unit and highly trained personnel began responding in September to select 911 calls in Santa Monica in coordination with the Santa Monica Fire Department. With support from t...
Source: UCLA Newsroom: Health Sciences - October 26, 2017 Category: Universities & Medical Training Source Type: news

Behavioral and neurophysiological mechanisms underlying motor skill learning in patients with post-stroke hemiparesis
Skilled actions of daily life such as reaching across a busy table to pick a coffee mug are often performed with accurate, yet fast and efficient arm movements. Such complex skilled actions require optimization of speed and accuracy; and rely on efficient planning and execution (Begliomini et al., 2014; Fang et al., 2015; Orban de Xivry et al., 2017; Stewart et al., 2013). Following a neurological insult such as stroke, skilled arm movements are greatly impaired in the paretic (weaker) arm such that task performance is slow, inaccurate and fragmented (Cirstea et al., 2003; Levin, 1996; Liu et al., 2013; Shaikh et al., 2014...
Source: Clinical Neurophysiology - October 25, 2017 Category: Neuroscience Authors: Shailesh Kantak, Robert McGrath, Nazaneen Zahedi, Dustin Luchmee Source Type: research

Comprehensive Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attack or Mild Stroke: PSYCHOLOGICAL PROFILE AND OUTCOMES
Purpose: Having previously reported that comprehensive cardiac rehabilitation (CCR) is effective for secondary prevention post-transient ischemic attack (TIA)/mild nondisabling stroke (MNDS), we present psychometric findings for the same sample that elucidate subacute TIA/MNDS psychological outcomes and test whether CCR would be independently associated with psychological improvements. Methods: In this prospective cohort trial patients with ≥1 risk factor, recruited from a stroke prevention clinic within 12 months (mean = 11.5 weeks) post-TIA/MNDS, entered CCR. Results: Of the 110 recruited patients, 100 (mean age = 65...
Source: Journal of Cardiopulmonary Rehabilitation - October 31, 2017 Category: Rehabilitation Tags: Cardiovascular Rehabilitation Source Type: research

Piloting a Sex-Specific, Technology-Enhanced, Active Learning Intervention for Stroke Prevention in Women
ABSTRACT: Background: Recent studies reveal deficiencies in stroke awareness and knowledge of risk factors among women. Existing stroke education interventions may not address common and sex-specific risk factors in the population with the highest stroke-related rate of mortality. Objective: This pilot study assessed the efficacy of a technology-enhanced, sex-specific educational program (“SISTERS”) for women’s knowledge of stroke. Methods: This was an experimental pretest-posttest design. The sample consisted of 150 women (mean age, 55 years) with at least 1 stroke risk factor. Participants were randomized to either...
Source: Journal of Neuroscience Nursing - November 8, 2017 Category: Neuroscience Tags: Article Source Type: research

Using Mahalanobis Distance to Evaluate Recovery in Acute Stroke.
Discussion: In the acute phase of stroke using Mahalanobis distance it is possible to distinguish between recovery, normal learning, and gerneralized learning deficits thereby identifying likely candidates for further cognitive assessment and rehabilitation. PMID: 29126201 [PubMed - as supplied by publisher]
Source: Archives of Clinical Neuropsychology - November 8, 2017 Category: Psychiatry & Psychology Authors: Tehan H, Witteveen K, Tolan GA, Tehan G, Senior GJ Tags: Arch Clin Neuropsychol Source Type: research

Behavioral and neurophysiological mechanisms underlying motor skill learning in patients with post-stroke hemiparesis.
CONCLUSIONS: When execution deficits are accounted for, patients with stroke demonstrate relatively intact motor skill learning with the paretic arm. Paretic arm learning is accompanied by modulations in corticospinal and transcallosal mechanisms. SIGNIFICANCE: Functional recovery after stroke relies on ability for skill learning and the underlying mechanisms. PMID: 29127826 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - November 8, 2017 Category: Neurology Authors: Kantak S, McGrath R, Zahedi N, Luchmee D Tags: Clin Neurophysiol Source Type: research

PCSK9 Variants, LDL-Cholesterol, and Neurocognitive Impairment: The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.
Conclusions -These results suggest life-long exposure to low PCSK9 levels and cumulative exposure to lower LDL-C are not associated with neurocognitive effects in African Americans. PMID: 29146683 [PubMed - as supplied by publisher]
Source: Circulation - November 16, 2017 Category: Cardiology Authors: Mefford MT, Rosenson RS, Cushman M, Farkouh ME, McClure LA, Wadley VG, Irvin MR, Bittner VA, Safford MM, Somaratne R, Monda KL, Muntner P, Levitan EB Tags: Circulation Source Type: research

Stroke Rehab Technology Aims To Speed Healing
Watching someone who has suffered a stroke try to perform everyday actions such as walking down the sidewalk or even bringing a cup to their lips can serve as a sobering reminder of how fragile full and robust health is, and also serves as an inspiration for those dedicated to improving the lives of those patients. Steven Plymale, recently named CEO of Toronto-based MyndTec, said his reaction to watching videos of patients using the company's MyndMove functional electrical stimulation (FES) rehabilitation system was one of the reasons he joined MyndTec. "They are very compelling," Plymale said of the demonstration videos,...
Source: MDDI - November 22, 2017 Category: Medical Devices Authors: Greg Goth Tags: Electronics Source Type: news