Interpretation of Complete Tumor Response on MRI Following Chemoradiotherapy of Rectal Cancer: Inter-Reader Agreement and Associated Factors in Multi-Center Clinical Practice
CONCLUSION: Inter-reader agreement was moderate for assessing CR on post-CRT MRI. Readers' varying standards on MRI interpretation (i.e., threshold effect), along with the use of rectal gel, initial tumor size, and initial cT stage, were significant factors associated with inter-reader agreement.PMID:38528693 | PMC:PMC10973736 | DOI:10.3348/kjr.2023.1213 (Source: Korean Journal of Radiology)
Source: Korean Journal of Radiology - March 26, 2024 Category: Radiology Authors: Hae Young Kim Seung Hyun Cho Jong Keon Jang Bohyun Kim Chul-Min Lee Joon Seok Lim Sung Kyoung Moon Soon Nam Oh Nieun Seo Seong Ho Park Source Type: research

Interpretation of Complete Tumor Response on MRI Following Chemoradiotherapy of Rectal Cancer: Inter-Reader Agreement and Associated Factors in Multi-Center Clinical Practice
CONCLUSION: Inter-reader agreement was moderate for assessing CR on post-CRT MRI. Readers' varying standards on MRI interpretation (i.e., threshold effect), along with the use of rectal gel, initial tumor size, and initial cT stage, were significant factors associated with inter-reader agreement.PMID:38528693 | PMC:PMC10973736 | DOI:10.3348/kjr.2023.1213 (Source: Korean J Radiol)
Source: Korean J Radiol - March 26, 2024 Category: Radiology Authors: Hae Young Kim Seung Hyun Cho Jong Keon Jang Bohyun Kim Chul-Min Lee Joon Seok Lim Sung Kyoung Moon Soon Nam Oh Nieun Seo Seong Ho Park Source Type: research

Interpretation of Complete Tumor Response on MRI Following Chemoradiotherapy of Rectal Cancer: Inter-Reader Agreement and Associated Factors in Multi-Center Clinical Practice
CONCLUSION: Inter-reader agreement was moderate for assessing CR on post-CRT MRI. Readers' varying standards on MRI interpretation (i.e., threshold effect), along with the use of rectal gel, initial tumor size, and initial cT stage, were significant factors associated with inter-reader agreement.PMID:38528693 | PMC:PMC10973736 | DOI:10.3348/kjr.2023.1213 (Source: Korean Journal of Radiology)
Source: Korean Journal of Radiology - March 26, 2024 Category: Radiology Authors: Hae Young Kim Seung Hyun Cho Jong Keon Jang Bohyun Kim Chul-Min Lee Joon Seok Lim Sung Kyoung Moon Soon Nam Oh Nieun Seo Seong Ho Park Source Type: research

Interpretation of Complete Tumor Response on MRI Following Chemoradiotherapy of Rectal Cancer: Inter-Reader Agreement and Associated Factors in Multi-Center Clinical Practice
CONCLUSION: Inter-reader agreement was moderate for assessing CR on post-CRT MRI. Readers' varying standards on MRI interpretation (i.e., threshold effect), along with the use of rectal gel, initial tumor size, and initial cT stage, were significant factors associated with inter-reader agreement.PMID:38528693 | PMC:PMC10973736 | DOI:10.3348/kjr.2023.1213 (Source: Korean J Radiol)
Source: Korean J Radiol - March 26, 2024 Category: Radiology Authors: Hae Young Kim Seung Hyun Cho Jong Keon Jang Bohyun Kim Chul-Min Lee Joon Seok Lim Sung Kyoung Moon Soon Nam Oh Nieun Seo Seong Ho Park Source Type: research

Interpretation of Complete Tumor Response on MRI Following Chemoradiotherapy of Rectal Cancer: Inter-Reader Agreement and Associated Factors in Multi-Center Clinical Practice
CONCLUSION: Inter-reader agreement was moderate for assessing CR on post-CRT MRI. Readers' varying standards on MRI interpretation (i.e., threshold effect), along with the use of rectal gel, initial tumor size, and initial cT stage, were significant factors associated with inter-reader agreement.PMID:38528693 | PMC:PMC10973736 | DOI:10.3348/kjr.2023.1213 (Source: Korean Journal of Radiology)
Source: Korean Journal of Radiology - March 26, 2024 Category: Radiology Authors: Hae Young Kim Seung Hyun Cho Jong Keon Jang Bohyun Kim Chul-Min Lee Joon Seok Lim Sung Kyoung Moon Soon Nam Oh Nieun Seo Seong Ho Park Source Type: research

Cancers, Vol. 16, Pages 1281: Patient-Relevant Costs for Organ Preservation versus Radical Resection in Locally Advanced Rectal Cancer
ay Alexander Fabian Klaus Pietschmann Total neoadjuvant therapy (TNT) is an evolving treatment schedule for locally advanced rectal cancer (LARC), allowing for organ preservation in a relevant number of patients in the case of complete response. Patients who undergo this so-called “watch and wait” approach are likely to benefit regarding their quality of life (QoL), especially if definitive ostomy could be avoided. In this work, we performed the first cost-effectiveness analysis from the patient perspective to compare costs for TNT with radical resection after neoadjuvant chemoradiation ...
Source: Cancers - March 26, 2024 Category: Cancer & Oncology Authors: Georg W. Wurschi Alexander R ühle Justus Domschikowski Maike Trommer Simone Ferdinandus Jan-Niklas Becker Simon Boeke Mathias Sonnhoff Christoph A. Fink Lukas K äsmann Melanie Schneider Elodie Bockelmann David Krug Nils H. Nicolay Alexander Fabian Klaus Tags: Article Source Type: research

Identification of unique rectal cancer-specific subtypes
British Journal of Cancer, Published online: 26 March 2024; doi:10.1038/s41416-024-02656-0Identification of unique rectal cancer-specific subtypes (Source: British Journal of Cancer)
Source: British Journal of Cancer - March 26, 2024 Category: Cancer & Oncology Authors: Batuhan Kisakol Anna Matveeva Manuela Salvucci Alexander Kel Elizabeth McDonough Fiona Ginty Daniel B. Longley Jochen H. M. Prehn Source Type: research

Controversia en la estadificaci ón inicial ganglionar en el Ca de recto (¿RM o PET/TC?)
CONCLUSIONS: In the initial nodal staging of rectal cancer MRI overstages relative to PET/CT. Both modalities are complementary, PET/CT offers higher specificity and MRI higher sensitivity.PMID:38527730 | DOI:10.1016/j.remnie.2024.500004 (Source: Molecular Medicine)
Source: Molecular Medicine - March 25, 2024 Category: Molecular Biology Authors: Elena L ópez Llobet M ónica Coronado Poggio Carmen Lancha Hern ández Carmen Mart ín Hervás Daniela Travaglio Morales Dom énico Monachello Araujo Sonia Rodado Marina Lu ís Domínguez Gadea Source Type: research

Fluorescence guidance using near-infrared fluorescent clips in robotic rectal surgery: a case series
ConclusionThe rate of intraoperative clip detection, oncological assessment, including DRM, and the number of lymph nodes indicate that the utility of fluorescence-guided methods with NIRFCs is feasible for rectal cancer. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - March 23, 2024 Category: Gastroenterology Source Type: research

Research progress of robot and laparoscope in postoperative complications of rectal cancer
AbstractRectal cancer is one of the most common malignant tumours worldwide, and it is also one of the major diseases that seriously threatens human life and health. At present, the main treatment for rectal cancer is still surgical treatment. The surgical methods have been rapidly developed from the previous open surgery to the current minimally invasive surgery. At present, there are two main minimally invasive surgeries: robotic surgery and laparoscopic surgery. Due to the particularity of rectal cancer surgery, more and more studies have shown that robotic rectal cancer surgery has more advantages than laparoscopic rec...
Source: Journal of Robotic Surgery - March 23, 2024 Category: Surgery Source Type: research

Fluorescence guidance using near-infrared fluorescent clips in robotic rectal surgery: a case series
ConclusionThe rate of intraoperative clip detection, oncological assessment, including DRM, and the number of lymph nodes indicate that the utility of fluorescence-guided methods with NIRFCs is feasible for rectal cancer. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - March 23, 2024 Category: Gastroenterology Source Type: research

Colon and rectal cancer: An emergent public health problem
This study is a review of CRC pathology and includes the most recent scientific evidence regarding this pathology, as well as a diagnosis of the epidemiological situation of CRC. Finally, the recommendation from a public health perspective will be discussed in detail taking into account the context and the most current recommendations.PMID:38515957 | PMC:PMC10950624 | DOI:10.3748/wjg.v30.i7.644 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - March 22, 2024 Category: Gastroenterology Authors: Marina Pinheiro David Nascimento Moreira Michele Ghidini Source Type: research

Colon and rectal cancer: An emergent public health problem
This study is a review of CRC pathology and includes the most recent scientific evidence regarding this pathology, as well as a diagnosis of the epidemiological situation of CRC. Finally, the recommendation from a public health perspective will be discussed in detail taking into account the context and the most current recommendations.PMID:38515957 | PMC:PMC10950624 | DOI:10.3748/wjg.v30.i7.644 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - March 22, 2024 Category: Gastroenterology Authors: Marina Pinheiro David Nascimento Moreira Michele Ghidini Source Type: research

Association Between Peritoneal Carcinomatosis Index (PCI) Assessed by CT and Pathological Parameters and Short-Term Prognosis of Rectal Cancer
CONCLUSION: Preoperative CT-PCI may be utilized to evaluate the short-term prognosis of patients who undergo radical surgery for rectal cancer after neoadjuvant therapy. This evaluation assists in guiding clinical diagnostic and therapeutic decision-making, allowing for prompt interventions and enhancing short-term patient outcomes.PMID:38518149 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Boyuan Zou Naishun Zhang Haicheng Gao Wenjie Li Shibo Liu Yankai Zhang Source Type: research

Treatment Options for Distal Rectal Cancer in the Era of Organ Preservation
Curr Treat Options Oncol. 2024 Mar 22. doi: 10.1007/s11864-024-01194-4. Online ahead of print.ABSTRACTThe introduction of total mesorectal excision into the radical surgery of rectal cancer has significantly improved the oncological outcome with longer survival and lower local recurrence. Traditional treatment modalities of distal rectal cancer, relying on radical surgery, while effective, take their own set of risks, including surgical complications, potential damage to the anus, and surrounding structure owing to the pursuit of thorough resection. The progress of operating methods as well as the integration of systemic t...
Source: Cancer Control - March 22, 2024 Category: Cancer & Oncology Authors: Chen Wang Xiaoliang Liu Weiping Wang Zheng Miao Xiaoyan Li Dingchao Liu Ke Hu Source Type: research