Precision CT ‑guided marking with India ink and microcoils for laparoscopic resection of a lateral lymph node recurrence of rectal cancer: A case report
Oncol Lett. 2024 Apr 12;27(6):266. doi: 10.3892/ol.2024.14399. eCollection 2024 Jun.ABSTRACTAlthough rarely used in laparoscopic surgery, computed tomography (CT)-guided marking is useful for targeting small lesions. The present study describes the performance of laparoscopic resection with preoperative CT-guided marking for lateral lymph node recurrence of rectal cancer. A 48-year-old man underwent laparoscopic low anterior resection with D3 lymph node dissection for rectal cancer (postoperative diagnosis, stage IIIb). Postoperative adjuvant chemotherapy was then administered. Solitary lymph node recurrence was observed i...
Source: Oncology Letters - April 25, 2024 Category: Cancer & Oncology Authors: Shunsuke Furukawa Masatsugu Hiraki Takeshi Oda Yukihiko Takahashi Ryuichiro Samejima Source Type: research

Development and validation of machine learning models and nomograms for predicting the surgical difficulty of laparoscopic resection in rectal cancer
The objective of this study is to develop and validate a machine learning (ML) prediction model for the assessment of laparoscopic total mesorectal excision (LaTME) surgery difficulty, as well as to identify i... (Source: World Journal of Surgical Oncology)
Source: World Journal of Surgical Oncology - April 25, 2024 Category: Cancer & Oncology Authors: Xiangyong Li, Zeyang Zhou, Bing Zhu, Yong Wu and Chungen Xing Tags: Research Source Type: research

Unveiling the promising anticancer effect of copper-based compounds: a comprehensive review
AbstractCopper is a necessary micronutrient for maintaining the well-being of the human body. The biological activity of organic ligands, especially their anticancer activity, is often enhanced when they coordinate with copper(I) and (II) ions. Copper and its compounds are capable of inducing tumor cell death through various mechanisms of action, including activation of apoptosis signaling pathways by reactive oxygen species (ROS), inhibition of angiogenesis, induction of cuproptosis, and paraptosis. Some of the copper complexes are currently being evaluated in clinical trials for their ability to map tumor hypoxia in vari...
Source: Journal of Cancer Research and Clinical Oncology - April 25, 2024 Category: Cancer & Oncology Source Type: research

Evaluation of anorectal function using real-time tissue elastography before and after preoperative chemoradiotherapy
ConclusionInternal anal sphincter sclerosis due to chemoradiotherapy may correlate to anorectal dysfunction. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - April 25, 2024 Category: Gastroenterology Source Type: research

External validation of the colorectal cancer risk score LiFeCRC using food frequency questions in the HUNT study
ConclusionReadily available clinical variables and food frequency questions in a modified LiFeCRC score can identify patients at risk of CRC and may improve primary prevention by motivating to lifestyle change or participation in the CRC screening programme. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - April 25, 2024 Category: Gastroenterology Source Type: research

Great Debates: Surgery or Watch and Wait After Total Neoadjuvant Therapy for Rectal Cancer
Am Surg. 2024 Apr 24:31348241248812. doi: 10.1177/00031348241248812. Online ahead of print.ABSTRACTLocally advanced rectal cancer has traditionally been treated with multimodal therapy including neoadjuvant chemoradiotherapy followed by surgical resection. More recent data suggests that in appropriate patients, total neoadjuvant treatment (TNT) makes it possible to adopt a "watch and wait" approach. Advocates for watch and wait argue that patients with a complete or near-complete clinical response to TNT have comparable overall and disease-free survival to their counterparts who undergo surgical resection, and also have a ...
Source: The American Surgeon - April 24, 2024 Category: Surgery Authors: Ayaa Ali Wang Fai Lee Michael P O'Leary Matthew Whealon Source Type: research

Minimally invasive versus open multivisceral resection for rectal cancer clinically invading adjacent organs: a propensity score-matched analysis
ConclusionMIS had several short-term advantages over open surgery, such as lower complication rates, faster recovery, and a shorter hospital stay, in rectal cancer patients who underwent multivisceral resection.Graphical abstract (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - April 24, 2024 Category: Surgery Source Type: research

Imaging segmentation mechanism for rectal tumors using improved U-Net
In radiation therapy, cancerous region segmentation in magnetic resonance images (MRI) is a critical step. For rectal cancer, the automatic segmentation of rectal tumors from an MRI is a great challenge. There... (Source: BMC Medical Imaging)
Source: BMC Medical Imaging - April 23, 2024 Category: Radiology Authors: Kenan Zhang, Xiaotang Yang, Yanfen Cui, Jumin Zhao and Dengao Li Tags: Research Source Type: research

Robotic-Assisted Surgery for Rectal Cancer: An Expedited Summary of the Clinical Evidence
CONCLUSIONS: Robotic-assisted rectal cancer surgery may result in similar or improved clinical outcomes compared with laparoscopic and open rectal cancer surgery.PMID:38645608 | PMC:PMC11031254 (Source: Ontario Health Technology Assessment Series)
Source: Ontario Health Technology Assessment Series - April 22, 2024 Category: General Medicine Authors: Ontario Health Source Type: research

Comment on: “Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial”
British Journal of Cancer, Published online: 22 April 2024; doi:10.1038/s41416-024-02690-yComment on: “Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial” (Source: British Journal of Cancer)
Source: British Journal of Cancer - April 22, 2024 Category: Cancer & Oncology Authors: Letian Qiao Yuan Liu Qiumin Yang Source Type: research

The urinary and sexual outcomes of robot-assisted versus laparoscopic rectal cancer surgery: a systematic review and meta-analysis
AbstractTo compare the urinary and sexual outcomes between robot-assisted rectal cancer (RC) surgery (RRCS) and laparoscopic RC surgery (LRCS) using a meta-analysis, searches were conducted of the Embase, PubMed, Cochrane Library, CNKI, and Wanfang databases. The International Prostate Symptom Score (IPSS) was the primary outcome. Eleven studies (790 patients with RRCS and 888 with LRCS) were included. The IPSS scores were significantly lower for RRCS than LRCS from baseline to 3  months (weighted mean difference [WMD] =  − 1.21, 95% confidence interval [CI]: − 1.8,-0.62,I2 = 89.9%), to 6 months (WMD...
Source: Surgery Today - April 21, 2024 Category: Surgery Source Type: research

The Association Between Religiosity, Spirituality and Colorectal Cancer Screening: A Longitudinal Analysis of Alberta ’s Tomorrow Project in Canada
AbstractWe explored longitudinal associations between religion/spirituality (R/S) Salience and R/S Attendance, and colorectal cancer screening, among adults aged  ≥ 50 years in Alberta, Canada. R/S Salience was not statistically significantly associated with colorectal cancer screening (adjusted odds ratio [aOR]: 1.06, 95% confidence interval [CI] 0.88–1.28). Conversely, R/S Attendance was statistically significantly associated with higher odds of colo rectal cancer screening: the aOR was 1.28 (95% CI 1.02–1.59) for participants attending services at least once a month and 1.31 (95% CI 1.01–1.69) for participants...
Source: Journal of Religion and Health - April 20, 2024 Category: Medical Ethics Source Type: research

Comparison of robotic versus laparoscopic surgery for visceral obesity in mid –low rectal cancer: a propensity-matched analysis
AbstractObesity is becoming more and more common, and measuring visceral fat area (VFA) is a useful diagnostic technique for visceral obesity (VO). The purpose of this research is to compare the surgical results of robotic versus laparoscopic rectal surgery, with a focus on assessing the benefits of the latter method for treating both VO and mid –low rectal cancer. Patients receiving laparoscopic or robotic anterior rectal excision at Northern Jiangsu People’s Hospital’s general surgery department were included in the retrospective analysis. 242 people in all took part in the study; 121 cases were assigned to the rob...
Source: Journal of Robotic Surgery - April 20, 2024 Category: Surgery Source Type: research

An Unauthorized Patient from Honduras Diagnosed with Rectal Cancer and the Role of Palliative Care in Preserving Life
1. Self-report their ability to identify common biases encountered by unauthorized patients in the healthcare setting.2. Self-report their ability to recognize the expanded role the Interdisciplinary Palliative Care Team plays in caring for unauthorized patients facing serious illnesses. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Suha Na Javeed, Tara McLaughlin-Whyte, Marta Gordon-Duffis, Grace N. La Torre Source Type: research