Colon cancer in the young: contributing factors and short-term surgical outcomes
AbstractBackgroundThe incidence in young patients has increased significantly over the last few decades. The aim of this study is to evaluate demographic and tumor characteristics of young patients and analyze the short-term surgical outcomes of patients undergoing surgery.MethodsWe performed a 2-year review (2015 –2016) of the ACS-NSQIP and included all patients with CC who underwent surgical management. Patients were stratified into two groups: early-onset CC (
Source: International Journal of Colorectal Disease - October 17, 2019 Category: Gastroenterology Source Type: research

MiR-218 and miR-100 polymorphisms as markers of irinotecan-based chemotherapy response in metastatic colorectal cancer
ConclusionsGA/AA genotypes of rs11134527 miR-218 and CT/TT genotypes of rs1834306 miR-100 polymorphisms could serve as prognostic biomarkers of TTP and OS. Carriers of the A allele of the miR-218 rs11134527 and T allele of the miR-100 rs1834306 polymorphisms are more likely not to respond to irinotecan-based therapies. However, further studies in larger patient populations are required. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - October 9, 2019 Category: Gastroenterology Source Type: research

ERAS, length of stay and private insurance: a retrospective study
ConclusionEven when objective criteria for readiness for discharge have been fulfilled, patients and/or doctors often do not feel comfortable with hospital discharge at this time point. Length of stay, even within an ERAS program, is still influenced by several non-medical factors and is therefore not a precise surrogate marker of outcomes. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - October 8, 2019 Category: Gastroenterology Source Type: research

Prophylactic negative wound therapy in laparotomy wounds (PROPEL trial): randomized controlled trial
This study is registered withClinicalTrials.gov (NCT number NCT03871023). (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 16, 2019 Category: Gastroenterology Source Type: research

Time-saving polyp detection in colon capsule endoscopy: evaluation of a novel software algorithm
ConclusionCollage mode might allow for a quick review of CCE videos with a high polyp detection rate for experienced CCE readers. Future prospective studies should include CCE collage mode for rapid polyp detection to further prove the feasibility of practical colon polyp detection by CCE and possibly support the role of CCE as a screening tool in CRC prevention. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 13, 2019 Category: Gastroenterology Source Type: research

Prognostic role of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with midgut neuroendocrine tumors undergoing resective surgery
ConclusionIn patients with midgut NET, an impaired adaptive immune response, as suggested by a high NLR ratio, was associated to the presence of distant metastasis and in particular of peritoneal metastasis. This information may be helpful when planning the treatment of a patient with a midgut NET. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 13, 2019 Category: Gastroenterology Source Type: research

Feasibility and safety of laparoscopic colorectal surgeries for patients with left ventricular assist device
ConclusionEven though the management of patients having a LVAD is challenging and needs a multidisciplinary approach, reported literatures have shown the safety and feasibility of laparoscopic interventions for colorectal surgeries. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 13, 2019 Category: Gastroenterology Source Type: research

Feasibility, acceptance, safety, and effectiveness of antibiotic therapy as alternative treatment approach to appendectomy in uncomplicated acute appendicitis
ConclusionsAppendectomy remains the most effective treatment for the definitive cure of acute appendicitis. However, antibiotic therapy can be a safe alternative approach for selected patients with uncomplicated acute appendicitis.Trial registrationDRKS00010401 (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 12, 2019 Category: Gastroenterology Source Type: research

Long-term tumour outcomes of self-expanding metal stents as ‘bridge to surgery’ for the treatment of colorectal cancer with malignant obstruction: a systematic review and meta-analysis
ConclusionSEMS implantation was a viable alternative in malignant left colon obstruction as a transition to surgery; its long-term survival results, including 5-year DFS and overall survival, were equivalent to those of emergent surgery. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 12, 2019 Category: Gastroenterology Source Type: research

Intussusception caused by typhlitis: a rare complication in a patient with acute lymphoblastic leukemia after chemotherapy
AbstractIntroductionIntussusception, which is common in pediatric patients but rare in adults with leukemia, usually presents with an intralumenal lesion as a lead point in adults.Case reportWe herein report the case of a 38-year-old female who developed right lower quadrant abdominal pain and fever on day 16 of chemotherapy. Abdominal computed tomography showed ileocecal intussusception. The patient underwent surgery, and the definitive pathological diagnosis was typhlitis leading to intussusception. Albeit very rare in adults, typhlitis-induced intussusception should be suspected in those with leukemia presenting with ab...
Source: International Journal of Colorectal Disease - September 11, 2019 Category: Gastroenterology Source Type: research

Acute mesenteric ischemia (AMI): absence of renal insufficiency and performance of early bowel resection may indicate improved outcomes
ConclusionsAMI remains a rare but oftentimes fatal disease. Our study provides evidence that outcome may depend on the AMI subtype, presence of renal insufficiency, and early bowel resection. Further research should help individualize treatment for optimized outcomes. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 11, 2019 Category: Gastroenterology Source Type: research

Emergent colectomy rates decreased while elective ileal pouch rates were stable over time: a nationwide inpatient sample study
ConclusionsThere has been a significant decline in emergent UC colectomy rates in the USA; however, the overall need for surgery appears unchanged given stable IPAA rates. This suggests a limited impact on overall surgery rates with a shift from emergent to elective procedures. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 11, 2019 Category: Gastroenterology Source Type: research

Ventral rectopexy with biological mesh for recurrent disorders of the posterior pelvic organ compartment
ConclusionsVMR with biological mesh is a safe and effective option for patients with recurrent posterior pelvic organ prolapse. It reduces functional symptoms, has a low complication rate, and promotes patient satisfaction. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 10, 2019 Category: Gastroenterology Source Type: research

Incidence of wound dehiscence after colorectal cancer surgery: results from a national population-based register for colorectal cancer
DiscussionPatients reoperated for wound dehiscence face a significantly higher postoperative mortality than those without. Risk factors include male gender, age>  70 years, obesity, history of chronic obstructive pulmonary disease, and history of generalised inflammatory disease. Patients at high risk for developing wound dehiscence may, if identified preoperatively, benefit from active prevention measures implemented in routine surgical practice. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 9, 2019 Category: Gastroenterology Source Type: research

A challenging diagnosis of mesenchymal neoplasm of the colon: colonic dedifferentiated liposarcoma with lymph node metastases —a case report and review of the literature
ConclusionsThe present case was a challenging diagnosis both at presurgical and histopathological level because it strongly mimicked a colonic adenocarcinoma. This was due to non-specific clinical and radiological presentation, to the non-characteristic histologic morphology and to the misleading presence of lymph node metastases. Malignant stromal tumors of the gastrointestinal tract beyond gist are fairly rare entities. Colonic dedifferentiated liposarcoma must be kept in mind and must be considered in the differential diagnosis of gastrointestinal tumors. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 9, 2019 Category: Gastroenterology Source Type: research

An updated systematic review and meta-analysis about the safety and efficacy of infliximab biosimilar, CT-P13, for patients with inflammatory bowel disease
ConclusionCT-P13 is effective and well tolerated in short and long-term periods. Switching to CT-P13 is recommended for the management of IBD. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 6, 2019 Category: Gastroenterology Source Type: research

Disease phenotype rather than treatment strategy impacts the long-term quality of life in patients with diverticular disease
ConclusionIn contrast to complicated disease, the uncomplicated diverticular disease is associated with an impaired long-term quality of life especially in domains composing mental health scores independently of chosen treatment strategy.Study registrationThe study is registered with the Research Registry at June 19, 2019.Research registry UIN:researchregistry4959. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 6, 2019 Category: Gastroenterology Source Type: research

Impact of age on toxicity and efficacy of 5-FU-based combination chemotherapy among patients with metastatic colorectal cancer; a pooled analysis of five randomized trials
AbstractObjectiveTo assess the impact of age on toxicity and efficacy outcomes of metastatic colorectal cancer treated with 5FU-based combination chemotherapy.MethodsProject Data Sphere (PDS) platform has been accessed and de-identified datasets of the following clinical trials were downloaded (NCT00272051; NCT00305188; NCT00115765; NCT00364013; and NCT00384176). Multivariable logistic regression analysis was used to assess the impact of age (
Source: International Journal of Colorectal Disease - September 6, 2019 Category: Gastroenterology Source Type: research

Transanal total mesorectal excision (TaTME): are we doing it for the right indication? An assessment of the external validity of published online video resources
ConclusionsThere is considerable interest in TaTME videos. Lack of consensus on reporting of these videos limits the educational value of these resources, which are missing important patient details and postoperative outcomes. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 5, 2019 Category: Gastroenterology Source Type: research

Angiotensin I-converting enzyme inhibitors/angiotensin II receptor blockers may reduce tumor recurrence in left-sided and early colorectal cancers
AbstractBackgroundAngiotensin signaling is suggested to be involved in tumorigenesis, tumor proliferation, and metastases. In colorectal cancer (CRC), it was demonstrated that angiotensin I-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) may reduce the risk of CRC; however, their impact on tumor recurrence remains unknown. Therefore, in this study, we evaluated the impact of ACEIs/ARBs on tumor recurrence in CRC patients.Patients and methodsWe retrospectively investigated the clinicopathological data of 461 stage I –III CRC patients. We divided the patients into those who took an ACEI...
Source: International Journal of Colorectal Disease - September 2, 2019 Category: Gastroenterology Source Type: research

Outcomes following colonic stenting for malignant left-sided bowel obstruction: a systematic review of randomised controlled trials
ConclusionThis study observed that SEMS as a bridge to surgery is associated with good technical and clinical success, with low rates of perforation and permanent stoma. SEMS should be part of the treatment armamentarium for obstructing colorectal neoplasms, but careful patient selection and institutional expertise are important factors for success. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 2, 2019 Category: Gastroenterology Source Type: research

Additional surgery after endoscopic submucosal dissection for colorectal cancer: a review of 53 cases
ConclusionAdditional surgery after ESD for T1 colorectal cancer was effective and had good long-term outcomes. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 2, 2019 Category: Gastroenterology Source Type: research

Quality of life in patients treated for anal carcinoma —a systematic literature review
ConclusionIn conclusion, it is apparent that several functional problems affect the quality of life of patients with anal cancer. There are few studies which have investigated quality of life after treatment for anal cancer. Interventions to address issues related to anal cancer treatment may improve long-term quality of life in this patient group.Trial registrationCRD42017059787 (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 1, 2019 Category: Gastroenterology Source Type: research

Comparison of three-dimensional versus two-dimensional laparoscopic surgery for rectal cancer: a meta-analysis
ConclusionsIn summary, 3D laparoscopic rectal surgery appears to have advantages over 2D laparoscopic rectal surgery in terms of positive CRM and operation time; however, it is not better than 2D laparoscopic rectal surgery in terms of the conversion rate and postoperative complications. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - September 1, 2019 Category: Gastroenterology Source Type: research

Comparison of outcomes of continuation/discontinuation of 5-aminosalicylic acid after initiation of anti-tumor necrosis factor-alpha therapy in patients with inflammatory bowel disease
ConclusionsContinuation of 5-ASA after initiation of anti-tumor necrosis factor-alpha agents did not improve prognosis in Korean IBD patients compared with that of those who discontinued 5-ASA during maintenance treatment, particularly in patients who experienced more than two disease aggravations. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 31, 2019 Category: Gastroenterology Source Type: research

Normal colonic transit time predicts the outcome of colonic manometry in patients with chronic constipation —an exploratory study
ConclusionColonic manometry should be considered in therapy-refractory STC patients in order to further delineate colonic motility. However, in this exploratory study, for patients presenting with NTC on a radio-opaque marker study, colonic manometry does not appear to have added value. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 31, 2019 Category: Gastroenterology Source Type: research

The risk factors for urinary dysfunction after autonomic nerve-preserving rectal cancer surgery: a multicenter retrospective study at Yokohama Clinical Oncology Group (YCOG1307)
AbstractAimThe aim of this retrospective study was to evaluate the frequency and risk factors of urinary dysfunction after autonomic nerve-preserving surgery for rectal cancer.MethodsThis was a retrospective multiinstitution study of 1002 rectal cancer patients conducted between January 2008 and December 2012 in Yokohama Clinical Oncology Group. Patients who had preoperative urinary dysfunction or had not undergone autonomic nerve preservation surgery were excluded. Urinary dysfunction was defined as that with a Clavien-Dindo classification grade ≥ 2. Patient-, tumor-, and surgery-related variables were examined ...
Source: International Journal of Colorectal Disease - August 30, 2019 Category: Gastroenterology Source Type: research

Familial and non-familial risk factors associated with colorectal cancer survival in young and middle-aged patients
AbstractBackgroundSurvival following colorectal cancer (CRC) survival may be influenced by a number of factors including family history, individual medical history, and comorbidities. The impact of these factors may vary based on the patient ’s age.MethodsThe study cohort consisted of individuals born in Western Australia between 1945 and 1996, who had been diagnosed with CRC prior to 2015 (n = 3220). Hospital, cancer, and mortality data were extracted for each patient from state health records and were used to identify potential risk factors associated with CRC survival. Family linkage data, in combina...
Source: International Journal of Colorectal Disease - August 30, 2019 Category: Gastroenterology Source Type: research

Post-polypectomy bleeding in hot-snare polypectomy of colonic polyps under continued warfarin or short interruption of direct oral anticoagulants
ConclusionsOur study affirms the recommendations of JGES for the management of anticoagulants in patients who undergo colonic polypectomy regarding post-polypectomy bleeding. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 30, 2019 Category: Gastroenterology Source Type: research

Absence of a rectocele may be correlated with reduced internal anal sphincter function in patients with rectal intussusception and fecal incontinence
This study assessed the relationships between various pelvic floor abnormalities and anal sphincter function in patients with RI and FI.MethodsData for patients with RI, collected in a prospective pelvic floor database, were assessed retrospectively. All women with FI, without anal sphincter defect, were included. Data on anorectal physiology and evacuation proctography were analyzed.ResultsOf 397 patients with RI, 85, who had predominantly passive FI, met the inclusion criteria. Maximum resting pressure (MRP) was significantly lower in patients with rectoanal intussusception (RAI) than in those with rectorectal intussusce...
Source: International Journal of Colorectal Disease - August 30, 2019 Category: Gastroenterology Source Type: research

Mortality trends of colorectal cancer among overweight patients at the global and national levels
ConclusionThe increase in high-BMI-related CRC mortality suggests scarce attention to overweight in the current prevention strategies and highlights its priority in future prevention strategies for CRC. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 30, 2019 Category: Gastroenterology Source Type: research

Pneumatosis cystoides intestinalis in a patient with aseptic meningitis: a case report
ConclusionAs the outcomes of PCI range from benign to life-threatening, an accurate diagnosis must be made to prevent unnecessary abdominal surgeries. Benign PCI in a patient without PCI correlated to underlying diseases, but received short-term corticosteroid treatment should be considered. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 30, 2019 Category: Gastroenterology Source Type: research

Osseous metaplasia in a recurrent symptomatic rectal lesion: a rare occurrence
ConclusionOsseous metaplasia of the gastrointestinal tract is a rare occurrence that can be associated with benign polyps or malignancy. Certain markers have been shown to be linked to this process and polypectomy remains the gold standard of treatment; however, further research is warranted. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 28, 2019 Category: Gastroenterology Source Type: research

Treatment of complex recurrent fistula-in-ano by surgery combined to autologous bone marrow –derived mesenchymal stroma cells and platelet-rich plasma injection
ConclusionsTreatment of complex recurrent cryptoglandular fistula-in-ano by surgery combined to autologous bone marrow –derived MSCs and PRP injection seems safe in selected patients, allowing long-term healing. This procedure seems promising but further evaluation by clinical trials is warranted. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 27, 2019 Category: Gastroenterology Source Type: research

Does adjuvant chemotherapy improve the prognosis of patients after resection of pulmonary metastasis from colorectal cancer? A systematic review and meta-analysis
ConclusionIn conclusion, ACT does not provide survival benefits for patients after resection of PM from CRC. ACT and targeted agents (BV) are not suggested for these patients. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 24, 2019 Category: Gastroenterology Source Type: research

Predictive parameters for the clinical course of Crohn ’s disease: development of a simple and reliable risk model
AbstractPurposeThe aim of our study was to identify clinical parameters in recently diagnosed Crohn ’s disease (CD) patients for prediction of their disease course.MethodsEPIC (Early Predictive parameters of Immunosuppressive therapy in Crohn ’s disease) is a prospective, observational study in 341 patients with a recent CD diagnosis (≤ 6 months), and naïve to immunosuppressants (IS) and anti-tumor necrosis factor α (TNF) agents. Patient characteristics were documented up to 2 years. In line with national and international guid elines, a complicated disease course was defined as n...
Source: International Journal of Colorectal Disease - August 24, 2019 Category: Gastroenterology Source Type: research

A hairy cavity: endoscopic therapy of a presacral recurrence of a complex pilonidal sinus
ConclusionFlexible endoscopy is, with its multiple therapeutic applications, an effective tool even in very complex inflammatory fistula and abscesses. Correctly indicated, it is with its minimally invasive character an excellent alternative to open surgical approaches. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 21, 2019 Category: Gastroenterology Source Type: research

Thank you list 2018
(Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 13, 2019 Category: Gastroenterology Source Type: research

Commentary on: “Randomized Phase II Trial of Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer: CAO/ARO/AIO-12”
(Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 12, 2019 Category: Gastroenterology Source Type: research

Prospective evaluation of the quality of life of patients undergoing surgery for colorectal cancer depending on the surgical technique
AbstractPurposeMonitoring of the quality of life of patients in addition to satisfactory survival indexes in order to choose an optimal treatment method is a trend in contemporary oncological surgery. The goal of the study was to prospectively evaluate the quality of life of patients treated for colorectal cancer depending on the type of surgical technique (open surgery (OS) vs. laparoscopic surgery (LS)).MethodsThe quality of life was evaluated thrice in the study groups (on the day of admission to the ward (I), 6  months (II), and 18 months after the procedure (III)). The following questionnaires were used in t...
Source: International Journal of Colorectal Disease - August 8, 2019 Category: Gastroenterology Source Type: research

Quality of life after end colostomy without mesh and with prophylactic synthetic mesh in sublay position: one-year results of the STOMAMESH trial
ConclusionsWhen forming an end colostomy, prophylactic synthetic mesh in a sublay position did not affect global QoL at 1-year follow-up, but stoma-related problems were fewer even in the presence of a clinically diagnosed PSH.Trial registrationNCT00917995 (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 7, 2019 Category: Gastroenterology Source Type: research

Young-onset colorectal cancer: hospitalization trends and gender disparities in the United States 2010 –2014
AbstractObjectivesStudy national hospitalization trends for colorectal cancer in patients younger than 50  years of age.MethodsPatients under age 50  years hospitalized for colorectal cancer were studied using the national inpatient sample databases (2010–2014), using validated ICD-CM-9 codes and hospitalizations represented per 100,000 total inpatient population.ResultsColorectal cancer hospitalizations demonstrated a significant uptrend in the 41 –50 years age group, with Caucasians and females most affected, stratifying for age and excluding those with a family history of colorectal cancer (p trend
Source: International Journal of Colorectal Disease - August 7, 2019 Category: Gastroenterology Source Type: research

Martius flap reconstruction for rectovaginal fistula after stapled hemorrhoidopexy (Longo operation): a case report
ConclusionsCases of postoperative RVF have been increasingly reported since the introduction of stapled hemorrhoidopexy. Patients with RVF can have a varying degree of symptoms. Diagnosis is primarily based on the patient ’s medical history together with a clinical examination. There are many surgical approaches for RVF. Anatomic fistula repair alone is associated with lower success rates compared with combined procedures with the adjunctive interposition of healthy, vascularised tissue. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - August 5, 2019 Category: Gastroenterology Source Type: research

A positive proximal resection margin is associated with anastomotic complications following primary ileocaecal resection for Crohn ’s disease
AbstractPurposesBowel resection in patients with Crohn ’s disease (CD) has a high reported rate of postoperative complications and surgical recurrence. A macroscopically normal resection margin is recommended in CD surgery as wider margins do not translate in reduced recurrence rates. The aim of this study was to evaluate the association between resec tion margin status and anastomotic complications following ileocaecal resection for primary CD.MethodsAll patients treated with ileocaecal resection for primary CD from 2010 to 2018 were included in this retrospective observational study. Emergency operations and recurr...
Source: International Journal of Colorectal Disease - August 3, 2019 Category: Gastroenterology Source Type: research

The influence of pulmonary comorbidities on treatment choice and short-term surgical outcomes among elderly patients with colorectal cancer
AbstractPurposeMost elderly patients with colorectal cancer have comorbidities and reduced functional reserve, which may increase their risks of postoperative morbidity and mortality, and subsequently influence the treatment choice. Therefore, this study aimed to investigate the treatment choice and compare laparoscopic and open surgery in this setting.MethodsThis retrospective study evaluated 118 patients with colorectal cancer ( ≥ 85 years old between January 2007 and February 2018) to determine the influence of comorbidities on treatment choice, as well as the safety and feasibility of laparoscopic s...
Source: International Journal of Colorectal Disease - July 18, 2019 Category: Gastroenterology Source Type: research

Prognostic value of N1c in colorectal cancer: a large population-based study using propensity score matching
AbstractPurposeWe conducted this large population-based study to investigate the prognostic significance of N1c.MethodsPatients diagnosed with colorectal cancer from the surveillance, epidemiology, and end results (SEER) database between January 1, 2010, and December 31, 2010, were included in the sample. The primary outcome of interest used in our study was cause-specific survival (CSS). Cox proportional hazards models and Kaplan –Meier methods were used to evaluate the prognostic value of N1c. Propensity score matching (PSM) was implemented to reduce the possibility of selection bias using a logistic regression mod...
Source: International Journal of Colorectal Disease - July 18, 2019 Category: Gastroenterology Source Type: research

Synchronous pathologic findings in patients with colorectal cancer and preoperative incomplete colonoscopy
ConclusionsComplete perioperative colonoscopy in patients with CRC should be performed to reduce the rate of metachronous carcinoma. Postoperative completion of preoperative insufficiently colonoscoped patients is recommended. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - July 18, 2019 Category: Gastroenterology Source Type: research

Risk factors for proctectomy in consecutive Crohn ’s colitis surgical patients in a reference colorectal centre
ConclusionsThe duration of Crohn ’s disease, female gender and a history of perianal disease were significant risk factors for a proctectomy procedure. Future research should examine whether immunosuppressive and biological medications reduce the risk for proctectomy. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - July 18, 2019 Category: Gastroenterology Source Type: research

Appendicolith appendicitis is clinically complicated acute appendicitis —is it histopathologically different from uncomplicated acute appendicitis
AbstractPurposeAcute appendicitis may present as uncomplicated and complicated and these disease forms differ both epidemiologically and clinically. Complicated acute appendicitis has traditionally been defined as an appendicitis complicated by perforation or a periappendicular abscess, and an appendicolith represents a predisposing factor of complicated disease. There are histopathological differences between uncomplicated acute appendicitis and the previously established traditional forms of complicated acute appendicitis, but to our knowledge, the histopathological differences between uncomplicated acute appendicitis an...
Source: International Journal of Colorectal Disease - July 18, 2019 Category: Gastroenterology Source Type: research

Correction to: Quantifying the extent of fistulotomy. How much sphincter can we safely divide? A three-dimensional endosonographic study
In the Fig. 1 of the original published version of this article the numbers were switched as well as in the text of Results section, lines 5 and 6. The revised figure and the corrected text are now presented correctly in this article. (Source: International Journal of Colorectal Disease)
Source: International Journal of Colorectal Disease - July 18, 2019 Category: Gastroenterology Source Type: research