Preoperative prediction of perineural invasion of rectal cancer based on a magnetic resonance imaging radiomics model: A dual-center study
CONCLUSION: The CR model based on preoperative MRI radiomics features and clinical risk factors can preoperatively predict the PNI status of RC noninvasively, which facilitates individualized treatment of RC patients.PMID:38690027 | PMC:PMC11056922 | DOI:10.3748/wjg.v30.i16.2233 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - May 1, 2024 Category: Gastroenterology Authors: Yan Liu Bai-Jin-Tao Sun Chuan Zhang Bing Li Xiao-Xuan Yu Yong Du Source Type: research
Preoperative prediction of perineural invasion of rectal cancer based on a magnetic resonance imaging radiomics model: A dual-center study
CONCLUSION: The CR model based on preoperative MRI radiomics features and clinical risk factors can preoperatively predict the PNI status of RC noninvasively, which facilitates individualized treatment of RC patients.PMID:38690027 | PMC:PMC11056922 | DOI:10.3748/wjg.v30.i16.2233 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Yan Liu Bai-Jin-Tao Sun Chuan Zhang Bing Li Xiao-Xuan Yu Yong Du Source Type: research
The impact of robotic rectal cancer surgery at a Canadian regional cancer centre: a retrospective cohort study
CONCLUSION: Access to robotic rectal cancer surgery increased successful completion of MIS and shortened hospital stay, with a similar total cost of care. Robotic rectal cancer surgery can enhance patient outcomes in the Canadian setting.PMID:38692680 | DOI:10.1503/cjs.002523 (Source: Canadian Journal of Surgery)
Source: Canadian Journal of Surgery - May 1, 2024 Category: Surgery Authors: Sunil V Patel Vanessa Wiseman Lisa Zhang Shaila J Merchant Antonio Caycedo-Marulanda P Hugh MacDonald Source Type: research
Preoperative prediction of perineural invasion of rectal cancer based on a magnetic resonance imaging radiomics model: A dual-center study
CONCLUSION: The CR model based on preoperative MRI radiomics features and clinical risk factors can preoperatively predict the PNI status of RC noninvasively, which facilitates individualized treatment of RC patients.PMID:38690027 | PMC:PMC11056922 | DOI:10.3748/wjg.v30.i16.2233 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - May 1, 2024 Category: Gastroenterology Authors: Yan Liu Bai-Jin-Tao Sun Chuan Zhang Bing Li Xiao-Xuan Yu Yong Du Source Type: research
Preoperative prediction of perineural invasion of rectal cancer based on a magnetic resonance imaging radiomics model: A dual-center study
CONCLUSION: The CR model based on preoperative MRI radiomics features and clinical risk factors can preoperatively predict the PNI status of RC noninvasively, which facilitates individualized treatment of RC patients.PMID:38690027 | PMC:PMC11056922 | DOI:10.3748/wjg.v30.i16.2233 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Yan Liu Bai-Jin-Tao Sun Chuan Zhang Bing Li Xiao-Xuan Yu Yong Du Source Type: research
The impact of robotic rectal cancer surgery at a Canadian regional cancer centre: a retrospective cohort study
CONCLUSION: Access to robotic rectal cancer surgery increased successful completion of MIS and shortened hospital stay, with a similar total cost of care. Robotic rectal cancer surgery can enhance patient outcomes in the Canadian setting.PMID:38692680 | PMC:PMC11068423 | DOI:10.1503/cjs.002523 (Source: Canadian Journal of Surgery)
Source: Canadian Journal of Surgery - May 1, 2024 Category: Surgery Authors: Sunil V Patel Vanessa Wiseman Lisa Zhang Shaila J Merchant Antonio Caycedo-Marulanda P Hugh MacDonald Source Type: research
Spontaneous regression and rare relapse after excisional biopsy in long-term observation of 31 patients with primary conjunctival lymphoma
J Clin Exp Hematop. 2024 Apr 30. doi: 10.3960/jslrt.24002. Online ahead of print.ABSTRACTTo elucidate long-term outcome in primary conjunctival lymphoma, a review was conducted of 31 consecutive patients: 21 men and 10 women with an age range of 28 to 85 (median, 61) years at presentation and follow-up periods ranging from 1 to 19 (median, 7) years. Conjunctival lymphoma was on the right side in 10 patients, on the left side in 12, and on both sides in 9. Upper, lower, or both fornix lesions in 28 patients were all diagnosed as extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma), w...
Source: Journal of Clinical and Experimental Hematopathology : JCEH - April 29, 2024 Category: Hematology Authors: Toshihiko Matsuo Takehiro Tanaka Source Type: research
NLRX1: a key regulator in mitochondrial respiration and colorectal cancer progression
AbstractColorectal cancer (CRC) is a prevalent and aggressive malignancy with high mortality rates and significant risks to human well-being. Population-wide screening for tumor suppressor genes and oncogenes shows promise for reducing the incidence and fatality of CRC. Recent studies have suggested that NLRX1, an innate immunity suppressor, may play a role in regulating chronic inflammation and tumorigenesis. However, further investigation is needed to understand the specific role of NLRX1 in CRC. To evaluate the impact of NLRX1 on migration, invasion, and metastasis, two human colon cancer cell lines were studied in vitr...
Source: Medical Oncology - April 29, 2024 Category: Cancer & Oncology Source Type: research
Difficulties and Disparities in Colorectal Cancer End-of-Life Care: A Patient's Story
Clin Colon Rectal Surg DOI: 10.1055/s-0044-1786393Patients with advanced colorectal cancer nearing the end of life require a multidisciplinary approach to address the unique challenges they face. Using a case vignette, we outline the various stages of a patient's journey with advanced rectal cancer and the common obstacles to their care as they interface with the medical system. We highlight how Black persons might be vulnerable to differences in screening, treatment, procedural interventions, end-of-life care, and health care decision-making. The article also addresses how health inequities and barriers relating to concor...
Source: Clinics in Colon and Rectal Surgery - April 29, 2024 Category: Surgery Authors: Ranson, Stacy Noreika, Danielle Rivet, Emily B. Tags: Review Article Source Type: research
Conversion rate to open surgery during transanal total mesorectal excision (TaTME) for rectal cancer: a single-center experience
AbstractMinimally invasive techniques for rectal cancer have demonstrated considerable advantages in terms of faster recovery and less post-operative complications. However, due to the complex anatomy and a limited surgical field, conversion to open surgery is still sometimes required, with a negative impact on the short-and long-term outcomes. The purpose of this study was to analyse the conversion rate to open abdominal surgery during laparoscopic transanal total mesorectal excision (TaTME) procedures performed at a high-volume Italian referral center. All consecutive TaTME performed for mid-to-low rectal cancer between ...
Source: Updates in Surgery - April 28, 2024 Category: Surgery Source Type: research
The multidisciplinary management of locally advanced rectal cancer
Expert Rev Anticancer Ther. 2024 Apr 26. doi: 10.1080/14737140.2024.2349137. Online ahead of print.ABSTRACTINTRODUCTION: . The classic paradigm for the management of locally advanced rectal cancer (LARC) consists of (chemo)radiotherapy (C)RT), total mesorectal excision and adjuvant chemotherapy (CHT). At present, due to the high rate of distant metastasis (up to 30%), the total neoadjuvant therapy (TNT) with the administration of systemic CHT in the neoadjuvant setting has gained acceptance as standard of care.Our aim is to critically review current literature on LARC management and summarize the different approaches recen...
Source: Expert Review of Anticancer Therapy - April 27, 2024 Category: Cancer & Oncology Authors: Francesca De Felice Michelangelo Miccini Andrea Botticelli Michela Roberto Niccol ò Petrucciani Source Type: research
Evaluation of Stages, Treatment Protocols, and Outcomes of Colorectal Cancer among West Bank Patients
Conclusions: A high percentage of patients were diagnosed in advanced CRC stages. The treatment modes were adopted from general international guidelines; however, the cure rates were low, and mortality was high. More studies need to be undertaken to investigate the actual application of chemotherapy protocols, and survival would benefit from the involvement of clinical pharmacists in the chemotherapy protocol selection, dosing, frequency, and follow-up. The present study advocates for greater public awareness of CRC and attests to the merits of screening by primary care professionals, which can help to avoid this serious i...
Source: Clinical Colorectal Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Ibrahim O Sawaid Abraham O Samson Rowa Al-Ramahi Source Type: research
