An update on total neoadjuvant treatment of adenocarcinoma of the rectum
Bull Cancer. 2024 Mar 28:S0007-4551(24)00084-5. doi: 10.1016/j.bulcan.2024.02.004. Online ahead of print.ABSTRACTA major advance has been made in the management of rectal cancer, with the emergence in 2021 of total neoadjuvant treatment. The main publications from the RAPIDO and PRODIGE-23 trials reported a significant improvement in progression-free survival and the pathological complete response rate. The aim of this review is to synthesize recent data on neoadjuvant treatment of rectal cancer, to explain the long-term results of the RAPIDO and PRODIGE-23 trials, and to put them into perspective, considering current adva...
Source: Bulletin du Cancer - March 29, 2024 Category: Cancer & Oncology Authors: Maroussia Medioni Baptiste Cervantes Florence Huguet Jean-Baptiste Bachet Yann Parc Thierry Andr é J érémie H Lefèvre Romain Cohen Source Type: research

Misdiagnosis of multiple myeloma as postoperative bone metastasis of rectal cancer: A case report and literature review
Oncol Lett. 2024 Mar 14;27(5):208. doi: 10.3892/ol.2024.14341. eCollection 2024 May.ABSTRACTMultiple myeloma (MM) and bone metastases are both common malignant tumors of the skeleton that share similar clinical manifestations and radiological features. The development of MM following rectal cancer surgery is relatively rare in clinical practice and is easily misdiagnosed as bone metastasis. The present study reported on a patient with MM and postoperative rectal cancer. A 65-year-old man had been diagnosed with low rectal cancer (poorly differentiated, T3N1M0) 10 years prior and underwent curative treatment at that time. D...
Source: Oncology Letters - March 29, 2024 Category: Cancer & Oncology Authors: Yuanqi Huang Zhengquan Chen Kunming Wen Source Type: research

Clinical Outcomes of Ileostomy Closure during versus after Adjuvant Chemotherapy in Patients with Rectal Cancer
CONCLUSION: Early ileostomy closure can effectively reduce the duration of stoma status, duration of LARS, rectal stenosis, and stoma-related complications while not affecting surgical complications and oncological outcomes. Ileostomy closure should not be delayed because of adjuvant chemotherapy. However, follow-up should be strengthened to increase compliance and integrity with chemotherapy.PMID:38550348 | PMC:PMC10977340 | DOI:10.1155/2024/2410643 (Source: Canadian Journal of Gastroenterology)
Source: Canadian Journal of Gastroenterology - March 29, 2024 Category: Gastroenterology Authors: Fan He Fuyu Yang Chenglin Tang Defei Chen Dongqin Zhao Junjie Xiong Yu Zou Guoquan Huang Kun Qian Source Type: research

Misdiagnosis of multiple myeloma as postoperative bone metastasis of rectal cancer: A case report and literature review
Oncol Lett. 2024 Mar 14;27(5):208. doi: 10.3892/ol.2024.14341. eCollection 2024 May.ABSTRACTMultiple myeloma (MM) and bone metastases are both common malignant tumors of the skeleton that share similar clinical manifestations and radiological features. The development of MM following rectal cancer surgery is relatively rare in clinical practice and is easily misdiagnosed as bone metastasis. The present study reported on a patient with MM and postoperative rectal cancer. A 65-year-old man had been diagnosed with low rectal cancer (poorly differentiated, T3N1M0) 10 years prior and underwent curative treatment at that time. D...
Source: Oncology Letters - March 29, 2024 Category: Cancer & Oncology Authors: Yuanqi Huang Zhengquan Chen Kunming Wen Source Type: research

Clinical Outcomes of Ileostomy Closure during versus after Adjuvant Chemotherapy in Patients with Rectal Cancer
CONCLUSION: Early ileostomy closure can effectively reduce the duration of stoma status, duration of LARS, rectal stenosis, and stoma-related complications while not affecting surgical complications and oncological outcomes. Ileostomy closure should not be delayed because of adjuvant chemotherapy. However, follow-up should be strengthened to increase compliance and integrity with chemotherapy.PMID:38550348 | PMC:PMC10977340 | DOI:10.1155/2024/2410643 (Source: Canadian Journal of Gastroenterology)
Source: Canadian Journal of Gastroenterology - March 29, 2024 Category: Gastroenterology Authors: Fan He Fuyu Yang Chenglin Tang Defei Chen Dongqin Zhao Junjie Xiong Yu Zou Guoquan Huang Kun Qian Source Type: research