Alopecia and cancers: From basics to clinical practice
Bull Cancer. 2021 Jul 22:S0007-4551(21)00209-5. doi: 10.1016/j.bulcan.2021.04.011. Online ahead of print.ABSTRACTAlopecia, although long considered an unavoidable consequence of cancer therapy, currently presents a multifaceted challenge. The knowledge of the physiology of the hair and consequently of the pathophysiology of alopecia has led to show that there is not one but several types of alopecia. Transposed to the world of oncology, different types of alopecia and subsequently molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. Thus, in patients with cancer, alopeci...
Source: Bulletin du Cancer - July 26, 2021 Category: Cancer & Oncology Authors: Stanislas Quesada Alexandre Guichard Sarah Le Vigouroux Louise Baussard Fr édéric Fiteni Source Type: research

Alopecia and cancers: From basics to clinical practice
Bull Cancer. 2021 Jul 22:S0007-4551(21)00209-5. doi: 10.1016/j.bulcan.2021.04.011. Online ahead of print.ABSTRACTAlopecia, although long considered an unavoidable consequence of cancer therapy, currently presents a multifaceted challenge. The knowledge of the physiology of the hair and consequently of the pathophysiology of alopecia has led to show that there is not one but several types of alopecia. Transposed to the world of oncology, different types of alopecia and subsequently molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. Thus, in patients with cancer, alopeci...
Source: Bulletin du Cancer - July 26, 2021 Category: Cancer & Oncology Authors: Stanislas Quesada Alexandre Guichard Sarah Le Vigouroux Louise Baussard Fr édéric Fiteni Source Type: research

Alopecia and cancers: From basics to clinical practice
Bull Cancer. 2021 Jul 22:S0007-4551(21)00209-5. doi: 10.1016/j.bulcan.2021.04.011. Online ahead of print.ABSTRACTAlopecia, although long considered an unavoidable consequence of cancer therapy, currently presents a multifaceted challenge. The knowledge of the physiology of the hair and consequently of the pathophysiology of alopecia has led to show that there is not one but several types of alopecia. Transposed to the world of oncology, different types of alopecia and subsequently molecular pathways have been characterized, allowing a better understanding of the underlying mechanisms. Thus, in patients with cancer, alopeci...
Source: Bulletin du Cancer - July 26, 2021 Category: Cancer & Oncology Authors: Stanislas Quesada Alexandre Guichard Sarah Le Vigouroux Louise Baussard Fr édéric Fiteni Source Type: research

Evaluation of the practice of prescribing oral chemotherapy type "Capecitabine" by medical oncologist: A first study from Morocco
CONCLUSION: In Morocco, there is a great variability in prescription and follow-up practice for patients receiving oral chemotherapy. There is a lack of a national standardization with regards to the procedures of prescribing and monitoring patients to ensure the quality and safety of the oral chemotherapy prescription.PMID:34281729 | DOI:10.1016/j.bulcan.2021.04.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 20, 2021 Category: Cancer & Oncology Authors: Saoussane Kharmoum Adil Najdi Rabie Rahhali Meryem Meliani Saber Boutayeb Hind Mrabti Ibrahim El Ghissassi Said Afqir Naoufal Mellas Mohamed Ichou Fatima Zahra El M'Rabet Hassan Errihani Source Type: research

Evaluation of the practice of prescribing oral chemotherapy type "Capecitabine" by medical oncologist: A first study from Morocco
CONCLUSION: In Morocco, there is a great variability in prescription and follow-up practice for patients receiving oral chemotherapy. There is a lack of a national standardization with regards to the procedures of prescribing and monitoring patients to ensure the quality and safety of the oral chemotherapy prescription.PMID:34281729 | DOI:10.1016/j.bulcan.2021.04.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 20, 2021 Category: Cancer & Oncology Authors: Saoussane Kharmoum Adil Najdi Rabie Rahhali Meryem Meliani Saber Boutayeb Hind Mrabti Ibrahim El Ghissassi Said Afqir Naoufal Mellas Mohamed Ichou Fatima Zahra El M'Rabet Hassan Errihani Source Type: research

Evaluation of the practice of prescribing oral chemotherapy type "Capecitabine" by medical oncologist: A first study from Morocco
CONCLUSION: In Morocco, there is a great variability in prescription and follow-up practice for patients receiving oral chemotherapy. There is a lack of a national standardization with regards to the procedures of prescribing and monitoring patients to ensure the quality and safety of the oral chemotherapy prescription.PMID:34281729 | DOI:10.1016/j.bulcan.2021.04.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 20, 2021 Category: Cancer & Oncology Authors: Saoussane Kharmoum Adil Najdi Rabie Rahhali Meryem Meliani Saber Boutayeb Hind Mrabti Ibrahim El Ghissassi Said Afqir Naoufal Mellas Mohamed Ichou Fatima Zahra El M'Rabet Hassan Errihani Source Type: research

Evaluation of the practice of prescribing oral chemotherapy type "Capecitabine" by medical oncologist: A first study from Morocco
CONCLUSION: In Morocco, there is a great variability in prescription and follow-up practice for patients receiving oral chemotherapy. There is a lack of a national standardization with regards to the procedures of prescribing and monitoring patients to ensure the quality and safety of the oral chemotherapy prescription.PMID:34281729 | DOI:10.1016/j.bulcan.2021.04.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 20, 2021 Category: Cancer & Oncology Authors: Saoussane Kharmoum Adil Najdi Rabie Rahhali Meryem Meliani Saber Boutayeb Hind Mrabti Ibrahim El Ghissassi Said Afqir Naoufal Mellas Mohamed Ichou Fatima Zahra El M'Rabet Hassan Errihani Source Type: research

Evaluation of the practice of prescribing oral chemotherapy type "Capecitabine" by medical oncologist: A first study from Morocco
CONCLUSION: In Morocco, there is a great variability in prescription and follow-up practice for patients receiving oral chemotherapy. There is a lack of a national standardization with regards to the procedures of prescribing and monitoring patients to ensure the quality and safety of the oral chemotherapy prescription.PMID:34281729 | DOI:10.1016/j.bulcan.2021.04.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 20, 2021 Category: Cancer & Oncology Authors: Saoussane Kharmoum Adil Najdi Rabie Rahhali Meryem Meliani Saber Boutayeb Hind Mrabti Ibrahim El Ghissassi Said Afqir Naoufal Mellas Mohamed Ichou Fatima Zahra El M'Rabet Hassan Errihani Source Type: research

Autologous hematopoietic cells for severe autoimmune diseases: Guidelines of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) for immune monitoring and biobanking
The objectives are to provide practical recommandations for immune monitoring and biobanking of samples in patients with AD undergoing AHCT, for routine care purposes and investigational studies.PMID:34272057 | DOI:10.1016/j.bulcan.2021.03.020 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 17, 2021 Category: Cancer & Oncology Authors: Pauline Lansiaux S éverine Loisel Cristina Castilla-Llorente Claire Fontenille Sarah Kabdani Zora Marjanovic Gr égory Pugnet Mathieu Puyade Emilie Robert Louis Terriou Nassim Ait Abdallah Alexandre Thibault Jacques Maria Laure Michel Xavier Tr éton Ibr Source Type: research

Autologous hematopoietic cells for severe autoimmune diseases: Guidelines of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) for immune monitoring and biobanking
The objectives are to provide practical recommandations for immune monitoring and biobanking of samples in patients with AD undergoing AHCT, for routine care purposes and investigational studies.PMID:34272057 | DOI:10.1016/j.bulcan.2021.03.020 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 17, 2021 Category: Cancer & Oncology Authors: Pauline Lansiaux S éverine Loisel Cristina Castilla-Llorente Claire Fontenille Sarah Kabdani Zora Marjanovic Gr égory Pugnet Mathieu Puyade Emilie Robert Louis Terriou Nassim Ait Abdallah Alexandre Thibault Jacques Maria Laure Michel Xavier Tr éton Ibr Source Type: research

Autologous hematopoietic cells for severe autoimmune diseases: Guidelines of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) for immune monitoring and biobanking
The objectives are to provide practical recommandations for immune monitoring and biobanking of samples in patients with AD undergoing AHCT, for routine care purposes and investigational studies.PMID:34272057 | DOI:10.1016/j.bulcan.2021.03.020 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 17, 2021 Category: Cancer & Oncology Authors: Pauline Lansiaux S éverine Loisel Cristina Castilla-Llorente Claire Fontenille Sarah Kabdani Zora Marjanovic Gr égory Pugnet Mathieu Puyade Emilie Robert Louis Terriou Nassim Ait Abdallah Alexandre Thibault Jacques Maria Laure Michel Xavier Tr éton Ibr Source Type: research

Immunomonitoring of patients treated with CAR-T cells  for hematological malignancy: Guidelines from the CARTi group and the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
The objectives of this workshop were to determine, based on data from the literature and the experience of the centers, the immunological analyses to be carried out in patients treated with CAR-T cells. The recommendations relate to the characterization of the patient's immune cells at the time of apheresis, the characterization of the injected CAR-T cells, as well as the monitoring of the CAR-T cells and other parameters of immune reconstitution in the patient after administration of the treatment. Harmonization of practices will allow clinical-biological correlation studies to be carried out in patients treated in real l...
Source: Bulletin du Cancer - July 13, 2021 Category: Cancer & Oncology Authors: Marie Th érèse Rubio Pauline Varlet Vincent Allain Caroline Ballot Alexis Cuffel Marina Deschamps Christophe Ferrand Jacques Foguenne Edouard Forcade Anne Huynh Am élie Guihot Jean-Baptiste Latouche Claude Lemarie Guillaume Martinroche Florence Morin S Source Type: research

Immunomonitoring of patients treated with CAR-T cells  for hematological malignancy: Guidelines from the CARTi group and the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
The objectives of this workshop were to determine, based on data from the literature and the experience of the centers, the immunological analyses to be carried out in patients treated with CAR-T cells. The recommendations relate to the characterization of the patient's immune cells at the time of apheresis, the characterization of the injected CAR-T cells, as well as the monitoring of the CAR-T cells and other parameters of immune reconstitution in the patient after administration of the treatment. Harmonization of practices will allow clinical-biological correlation studies to be carried out in patients treated in real l...
Source: Bulletin du Cancer - July 13, 2021 Category: Cancer & Oncology Authors: Marie Th érèse Rubio Pauline Varlet Vincent Allain Caroline Ballot Alexis Cuffel Marina Deschamps Christophe Ferrand Jacques Foguenne Edouard Forcade Anne Huynh Am élie Guihot Jean-Baptiste Latouche Claude Lemarie Guillaume Martinroche Florence Morin S Source Type: research

Immunomonitoring of patients treated with CAR-T cells  for hematological malignancy: Guidelines from the CARTi group and the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
The objectives of this workshop were to determine, based on data from the literature and the experience of the centers, the immunological analyses to be carried out in patients treated with CAR-T cells. The recommendations relate to the characterization of the patient's immune cells at the time of apheresis, the characterization of the injected CAR-T cells, as well as the monitoring of the CAR-T cells and other parameters of immune reconstitution in the patient after administration of the treatment. Harmonization of practices will allow clinical-biological correlation studies to be carried out in patients treated in real l...
Source: Bulletin du Cancer - July 13, 2021 Category: Cancer & Oncology Authors: Marie Th érèse Rubio Pauline Varlet Vincent Allain Caroline Ballot Alexis Cuffel Marina Deschamps Christophe Ferrand Jacques Foguenne Edouard Forcade Anne Huynh Am élie Guihot Jean-Baptiste Latouche Claude Lemarie Guillaume Martinroche Florence Morin S Source Type: research

Immunomonitoring of patients treated with CAR-T cells  for hematological malignancy: Guidelines from the CARTi group and the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
The objectives of this workshop were to determine, based on data from the literature and the experience of the centers, the immunological analyses to be carried out in patients treated with CAR-T cells. The recommendations relate to the characterization of the patient's immune cells at the time of apheresis, the characterization of the injected CAR-T cells, as well as the monitoring of the CAR-T cells and other parameters of immune reconstitution in the patient after administration of the treatment. Harmonization of practices will allow clinical-biological correlation studies to be carried out in patients treated in real l...
Source: Bulletin du Cancer - July 13, 2021 Category: Cancer & Oncology Authors: Marie Th érèse Rubio Pauline Varlet Vincent Allain Caroline Ballot Alexis Cuffel Marina Deschamps Christophe Ferrand Jacques Foguenne Edouard Forcade Anne Huynh Am élie Guihot Jean-Baptiste Latouche Claude Lemarie Guillaume Martinroche Florence Morin S Source Type: research

Establishment of Hematopoietic cell transplantation program in developing countries  : Guidelines from the francophone Society of bone marrow transplantation and cellular therapy (SFGM-TC)
Bull Cancer. 2021 Jul 8:S0007-4551(21)00204-6. doi: 10.1016/j.bulcan.2021.02.015. Online ahead of print.ABSTRACTHematopoietic cell transplantation (HCT) is the curative treatment for many malignant and non-malignant blood disorders and some solid cancers. However, transplant procedures are considered tertiary level care requiring a high degree of technicality and expertise and generating very high costs for hospital structures in developing countries as well as for patients without health insurance. During the 11th annual harmonization workshops of the francophone Society of bone marrow transplantation and cellular therapy...
Source: Bulletin du Cancer - July 12, 2021 Category: Cancer & Oncology Authors: Nabil Yafour Mohamed Amine Bekadja Patrice Chevallier Quentin Cabrera Tereza Coman Maria Elkababri Faty Hamzy Asmaa Quessar Amal Laamiri C écile Pochon Ibrahim Yakoub-Agha Mhamed Harif Source Type: research

Comparison of Modified Child-pugh (MCP), Albumin-bilirubin (ALBI), and Child-pugh (CP) score for predicting of survival in Hepatocellular Carcinoma Patients Treated with Transcatheter Arterial Chemoembolization
CONCLUSIONS: The stratification ability and prognostic predictive power of the MCP grade for HCC patients treated with TACE may be better than that of the ALBI grade or CP class.PMID:34247763 | DOI:10.1016/j.bulcan.2021.04.017 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 12, 2021 Category: Cancer & Oncology Authors: YouShun Liu Cong Cheng HuaBang Zhou ShouZi Hu Hao Wang QiaoHua Xie LiPing Lei Peng Wang GuoFang Liu HePing Hu Source Type: research

Human immunodeficiency virus and lymphoma
Bull Cancer. 2021 Jul 7:S0007-4551(21)00180-6. doi: 10.1016/j.bulcan.2021.03.014. Online ahead of print.ABSTRACTLymphomas remain a leading cause of morbidity and mortality for HIV-positive patients. The most common lymphomas include diffuse large B-cell lymphoma, Burkitt lymphoma, primary effusion lymphoma, plasmablastic lymphoma and Hodgkin lymphoma. Appropriate approach is determined by lymphoma stage, performans status, comorbidities, histological subtype, status of the HIV disease and immunosuppression. Treatment outcomes have improved due to chemotherapy modalities and effective antiretroviral therapy. This review sum...
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Illias Tazi Fatima Zahra Lahlimi Source Type: research

Cutaneous complications following hematopoietic stem cell transplantation
DISCUSSION: Hematopoietic stem cell allograft has many complications. The literature mainly specifies hematological and digestive complications, while skin complications are little described. Our series is special by reporting different types and mechanisms of skin complications that can occur; with a predominance of skin graft-on-host reactions and infections. It also reports an unusual Busulfan toxidermy.PMID:34246455 | DOI:10.1016/j.bulcan.2021.03.015 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Lamiae Araqi Houssaini Fouzia Hali Asm âa Quessar Farida Marnissi Soumiya Chiheb Source Type: research

Reprint of: SFOG Campus, A new group is born!
Bull Cancer. 2021 Jul 7:S0007-4551(21)00179-X. doi: 10.1016/j.bulcan.2020.10.024. Online ahead of print.NO ABSTRACTPMID:34246456 | DOI:10.1016/j.bulcan.2020.10.024 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Cherif Akladios Sofiane Bendifallah Elise Deluche Sarah Betrian Sophie Espenel Floriane Jochum Guillaume Babin Fr édéric Guyon Source Type: research

Scientific medicine and care relationship: From the therapeutic alliance to the therapeutic effect of the alliance
Bull Cancer. 2021 Jul 7:S0007-4551(21)00161-2. doi: 10.1016/j.bulcan.2021.02.011. Online ahead of print.ABSTRACTThe new paradigm of precision medicine in oncology questions today the respective place of evidence-based medicine and doctor-patient relationship. Based on the results of a randomized study comparing the efficacy of a homeopathic molecule in the prevention of nausea and vomiting induced by chemotherapy in non-metastatic breast cancer, this article extends and develops the discussion of maintaining an unresolved tension between medical art and medical science, between care and cure. This tension sets a base for t...
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Roland Chvetzoff Bernard Laurent Denis Baylot Gis èle Chvetzoff Source Type: research

Preoperative versus postoperative radiotherapy in soft tissue sarcomas: State of the art and perspectives
Bull Cancer. 2021 Jul 7:S0007-4551(21)00167-3. doi: 10.1016/j.bulcan.2021.03.012. Online ahead of print.ABSTRACTRadiation therapy is a standard treatment for limbs soft tissue sarcomas. Preoperative versus postoperative radiotherapy has been a controversial topic for years. With preoperative irradiation, the treatment volume is more limited, the delivered dose possibly lower and the tumor volume easier to delimit. Only one randomized trial compared these two irradiation sequences. The results in terms of local control and survival were equivalent but the risk of acute postoperative complications was higher if irradiation w...
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Antonin Levy Charles Honor é Sarah Dumont R émi Bourdais Andr éa Cavalcanti Matthieu Faron Carine Ngo Leila Haddag-Miliani Axel Le Cesne Olivier Mir C écile Le Péchoux Source Type: research

Human immunodeficiency virus and lymphoma
Bull Cancer. 2021 Jul 7:S0007-4551(21)00180-6. doi: 10.1016/j.bulcan.2021.03.014. Online ahead of print.ABSTRACTLymphomas remain a leading cause of morbidity and mortality for HIV-positive patients. The most common lymphomas include diffuse large B-cell lymphoma, Burkitt lymphoma, primary effusion lymphoma, plasmablastic lymphoma and Hodgkin lymphoma. Appropriate approach is determined by lymphoma stage, performans status, comorbidities, histological subtype, status of the HIV disease and immunosuppression. Treatment outcomes have improved due to chemotherapy modalities and effective antiretroviral therapy. This review sum...
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Illias Tazi Fatima Zahra Lahlimi Source Type: research

Cutaneous complications following hematopoietic stem cell transplantation
DISCUSSION: Hematopoietic stem cell allograft has many complications. The literature mainly specifies hematological and digestive complications, while skin complications are little described. Our series is special by reporting different types and mechanisms of skin complications that can occur; with a predominance of skin graft-on-host reactions and infections. It also reports an unusual Busulfan toxidermy.PMID:34246455 | DOI:10.1016/j.bulcan.2021.03.015 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Lamiae Araqi Houssaini Fouzia Hali Asm âa Quessar Farida Marnissi Soumiya Chiheb Source Type: research

Reprint of: SFOG Campus, A new group is born!
Bull Cancer. 2021 Jul 7:S0007-4551(21)00179-X. doi: 10.1016/j.bulcan.2020.10.024. Online ahead of print.NO ABSTRACTPMID:34246456 | DOI:10.1016/j.bulcan.2020.10.024 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Cherif Akladios Sofiane Bendifallah Elise Deluche Sarah Betrian Sophie Espenel Floriane Jochum Guillaume Babin Fr édéric Guyon Source Type: research

Scientific medicine and care relationship: From the therapeutic alliance to the therapeutic effect of the alliance
Bull Cancer. 2021 Jul 7:S0007-4551(21)00161-2. doi: 10.1016/j.bulcan.2021.02.011. Online ahead of print.ABSTRACTThe new paradigm of precision medicine in oncology questions today the respective place of evidence-based medicine and doctor-patient relationship. Based on the results of a randomized study comparing the efficacy of a homeopathic molecule in the prevention of nausea and vomiting induced by chemotherapy in non-metastatic breast cancer, this article extends and develops the discussion of maintaining an unresolved tension between medical art and medical science, between care and cure. This tension sets a base for t...
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Roland Chvetzoff Bernard Laurent Denis Baylot Gis èle Chvetzoff Source Type: research

Preoperative versus postoperative radiotherapy in soft tissue sarcomas: State of the art and perspectives
Bull Cancer. 2021 Jul 7:S0007-4551(21)00167-3. doi: 10.1016/j.bulcan.2021.03.012. Online ahead of print.ABSTRACTRadiation therapy is a standard treatment for limbs soft tissue sarcomas. Preoperative versus postoperative radiotherapy has been a controversial topic for years. With preoperative irradiation, the treatment volume is more limited, the delivered dose possibly lower and the tumor volume easier to delimit. Only one randomized trial compared these two irradiation sequences. The results in terms of local control and survival were equivalent but the risk of acute postoperative complications was higher if irradiation w...
Source: Bulletin du Cancer - July 11, 2021 Category: Cancer & Oncology Authors: Antonin Levy Charles Honor é Sarah Dumont R émi Bourdais Andr éa Cavalcanti Matthieu Faron Carine Ngo Leila Haddag-Miliani Axel Le Cesne Olivier Mir C écile Le Péchoux Source Type: research

Ethical issues facing hematopoietic stem cell transplantation in India
Bull Cancer. 2021 Jul 3:S0007-4551(21)00242-3. doi: 10.1016/j.bulcan.2021.04.018. Online ahead of print.ABSTRACTA successful Hematopoietic stem cell transplantation (HSCT) is often the only hope of survival for children suffering from a range of potentially life-threatening hematological malignancies. The financial, ethical, and emotional problems faced by the matched sibling donor and their recipient siblings during the HSCT are extremely complex and challenging. Herein, the authors have attempted to pen down these in the configuration of a poem.PMID:34229855 | DOI:10.1016/j.bulcan.2021.04.018 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 7, 2021 Category: Cancer & Oncology Authors: Manish Raturi Kunal Das Source Type: research

Ethical issues facing hematopoietic stem cell transplantation in India
Bull Cancer. 2021 Jul 3:S0007-4551(21)00242-3. doi: 10.1016/j.bulcan.2021.04.018. Online ahead of print.ABSTRACTA successful Hematopoietic stem cell transplantation (HSCT) is often the only hope of survival for children suffering from a range of potentially life-threatening hematological malignancies. The financial, ethical, and emotional problems faced by the matched sibling donor and their recipient siblings during the HSCT are extremely complex and challenging. Herein, the authors have attempted to pen down these in the configuration of a poem.PMID:34229855 | DOI:10.1016/j.bulcan.2021.04.018 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 7, 2021 Category: Cancer & Oncology Authors: Manish Raturi Kunal Das Source Type: research

Ethical issues facing hematopoietic stem cell transplantation in India
Bull Cancer. 2021 Jul 3:S0007-4551(21)00242-3. doi: 10.1016/j.bulcan.2021.04.018. Online ahead of print.ABSTRACTA successful Hematopoietic stem cell transplantation (HSCT) is often the only hope of survival for children suffering from a range of potentially life-threatening hematological malignancies. The financial, ethical, and emotional problems faced by the matched sibling donor and their recipient siblings during the HSCT are extremely complex and challenging. Herein, the authors have attempted to pen down these in the configuration of a poem.PMID:34229855 | DOI:10.1016/j.bulcan.2021.04.018 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 7, 2021 Category: Cancer & Oncology Authors: Manish Raturi Kunal Das Source Type: research

Ethical issues facing hematopoietic stem cell transplantation in India
Bull Cancer. 2021 Jul 3:S0007-4551(21)00242-3. doi: 10.1016/j.bulcan.2021.04.018. Online ahead of print.ABSTRACTA successful Hematopoietic stem cell transplantation (HSCT) is often the only hope of survival for children suffering from a range of potentially life-threatening hematological malignancies. The financial, ethical, and emotional problems faced by the matched sibling donor and their recipient siblings during the HSCT are extremely complex and challenging. Herein, the authors have attempted to pen down these in the configuration of a poem.PMID:34229855 | DOI:10.1016/j.bulcan.2021.04.018 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - July 7, 2021 Category: Cancer & Oncology Authors: Manish Raturi Kunal Das Source Type: research

National certification for gynecological cancer surgery
Bull Cancer. 2021 Jun 30:S0007-4551(21)00202-2. doi: 10.1016/j.bulcan.2021.03.019. Online ahead of print.ABSTRACTOBJECTIVE: In France, we are lacking an identified pathway for training in gynaecological cancer surgery. The four competent French learned societies: the SFOG, the CNGOF, the SFCO and the SCGP supported by the CNU of Obstetrics & Gynaecology, and UNICANCER agreed to materialize this course and attest it by a certification awarded by a national jury.MATERIAL AND METHODS: The national committee of certification in gynaecological oncology made up of ten members, representing the 6 concerned organizations, set ...
Source: Bulletin du Cancer - July 4, 2021 Category: Cancer & Oncology Authors: Cherif Akladios Émile Daraï Fran çois Golfier Fabrice Lecuru Pierre Collinet Catherine Uzan Vincent Lavou é Frederic Guyon Gwenael Ferron Denis Querleu Source Type: research

National certification for gynecological cancer surgery
Bull Cancer. 2021 Jun 30:S0007-4551(21)00202-2. doi: 10.1016/j.bulcan.2021.03.019. Online ahead of print.ABSTRACTOBJECTIVE: In France, we are lacking an identified pathway for training in gynaecological cancer surgery. The four competent French learned societies: the SFOG, the CNGOF, the SFCO and the SCGP supported by the CNU of Obstetrics & Gynaecology, and UNICANCER agreed to materialize this course and attest it by a certification awarded by a national jury.MATERIAL AND METHODS: The national committee of certification in gynaecological oncology made up of ten members, representing the 6 concerned organizations, set ...
Source: Bulletin du Cancer - July 4, 2021 Category: Cancer & Oncology Authors: Cherif Akladios Émile Daraï Fran çois Golfier Fabrice Lecuru Pierre Collinet Catherine Uzan Vincent Lavou é Frederic Guyon Gwenael Ferron Denis Querleu Source Type: research

National certification for gynecological cancer surgery
Bull Cancer. 2021 Jun 30:S0007-4551(21)00202-2. doi: 10.1016/j.bulcan.2021.03.019. Online ahead of print.ABSTRACTOBJECTIVE: In France, we are lacking an identified pathway for training in gynaecological cancer surgery. The four competent French learned societies: the SFOG, the CNGOF, the SFCO and the SCGP supported by the CNU of Obstetrics & Gynaecology, and UNICANCER agreed to materialize this course and attest it by a certification awarded by a national jury.MATERIAL AND METHODS: The national committee of certification in gynaecological oncology made up of ten members, representing the 6 concerned organizations, set ...
Source: Bulletin du Cancer - July 4, 2021 Category: Cancer & Oncology Authors: Cherif Akladios Émile Daraï Fran çois Golfier Fabrice Lecuru Pierre Collinet Catherine Uzan Vincent Lavou é Frederic Guyon Gwenael Ferron Denis Querleu Source Type: research

How to deal with an unexpected event that could alter the normal activity of cellular therapy? Recommendations of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
Bull Cancer. 2021 Jun 29:S0007-4551(21)00222-8. doi: 10.1016/j.bulcan.2021.05.002. Online ahead of print.ABSTRACTThe SARS-CoV-2 (COVID-19) pandemic has rapidly impacted cell therapy activities across the globe. Not only was this, unexpected event, a threat to patients who had previously received hematopoietic cell transplantation or other cell therapy such as CAR-T cells, but also, it was responsible for a disruption of cell therapy activities due to the danger of the virus and to the lack of solid scientific data on the management of patients and donors. The Francophone Society of Bone Marrow Transplantation and Cellular ...
Source: Bulletin du Cancer - July 3, 2021 Category: Cancer & Oncology Authors: Jacques Olivier Bay Yves Beguin Alexandre Carpentier C éline Dard Thierry Guillaume H élène Labussiere-Wallet Marie No ëlle Lacassagne S éverine Sauze Ibrahim Yakoub-Agha Yves Chalandon Source Type: research

How to deal with an unexpected event that could alter the normal activity of cellular therapy? Recommendations of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
Bull Cancer. 2021 Jun 29:S0007-4551(21)00222-8. doi: 10.1016/j.bulcan.2021.05.002. Online ahead of print.ABSTRACTThe SARS-CoV-2 (COVID-19) pandemic has rapidly impacted cell therapy activities across the globe. Not only was this, unexpected event, a threat to patients who had previously received hematopoietic cell transplantation or other cell therapy such as CAR-T cells, but also, it was responsible for a disruption of cell therapy activities due to the danger of the virus and to the lack of solid scientific data on the management of patients and donors. The Francophone Society of Bone Marrow Transplantation and Cellular ...
Source: Bulletin du Cancer - July 3, 2021 Category: Cancer & Oncology Authors: Jacques Olivier Bay Yves Beguin Alexandre Carpentier C éline Dard Thierry Guillaume H élène Labussiere-Wallet Marie No ëlle Lacassagne S éverine Sauze Ibrahim Yakoub-Agha Yves Chalandon Source Type: research

Palliative care in hematopoietic stem-cell transplanted patients: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
The objective of this work is to propose recommendations to promote the implementation of palliative care into transplant units.PMID:34176584 | DOI:10.1016/j.bulcan.2021.01.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 28, 2021 Category: Cancer & Oncology Authors: Alice Polomeni Chlo é Prod'homme Malika Ainaoui Adeline Bellec Aur élie Berr Jacinthe Bonneau Amandine Charbonnier Val érie Coiteux Eva de Berranger Thomas Descamps Marion Gire Murielle Goncalves Agn ès Ruscassié Ibrahim Yakoub-Agha C écile Borel Source Type: research

Intellectual disability and cancer in children: An analysis of the decision-making process
DISCUSSION: We propose three steps to guide the decision-making process in situations involving children with intellectual disability and cancer: 1/deeper understanding of the child through reinforced interactions with their caregivers, 2/better cross-boundary discussions, to improve the effectiveness of the multidisciplinary staff, and 3/more systematic ethical committees consultation.PMID:34176585 | DOI:10.1016/j.bulcan.2021.02.013 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 28, 2021 Category: Cancer & Oncology Authors: Marie-Th érèse Dangles Dominique Davous Gu énola Vialle Anne Auvrignon Elisabeth Angellier Franck Bourdeaut Source Type: research

Palliative care in hematopoietic stem-cell transplanted patients: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
The objective of this work is to propose recommendations to promote the implementation of palliative care into transplant units.PMID:34176584 | DOI:10.1016/j.bulcan.2021.01.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 28, 2021 Category: Cancer & Oncology Authors: Alice Polomeni Chlo é Prod'homme Malika Ainaoui Adeline Bellec Aur élie Berr Jacinthe Bonneau Amandine Charbonnier Val érie Coiteux Eva de Berranger Thomas Descamps Marion Gire Murielle Goncalves Agn ès Ruscassié Ibrahim Yakoub-Agha C écile Borel Source Type: research

Intellectual disability and cancer in children: An analysis of the decision-making process
DISCUSSION: We propose three steps to guide the decision-making process in situations involving children with intellectual disability and cancer: 1/deeper understanding of the child through reinforced interactions with their caregivers, 2/better cross-boundary discussions, to improve the effectiveness of the multidisciplinary staff, and 3/more systematic ethical committees consultation.PMID:34176585 | DOI:10.1016/j.bulcan.2021.02.013 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 28, 2021 Category: Cancer & Oncology Authors: Marie-Th érèse Dangles Dominique Davous Gu énola Vialle Anne Auvrignon Elisabeth Angellier Franck Bourdeaut Source Type: research

Palliative care in hematopoietic stem-cell transplanted patients: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
The objective of this work is to propose recommendations to promote the implementation of palliative care into transplant units.PMID:34176584 | DOI:10.1016/j.bulcan.2021.01.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 28, 2021 Category: Cancer & Oncology Authors: Alice Polomeni Chlo é Prod'homme Malika Ainaoui Adeline Bellec Aur élie Berr Jacinthe Bonneau Amandine Charbonnier Val érie Coiteux Eva de Berranger Thomas Descamps Marion Gire Murielle Goncalves Agn ès Ruscassié Ibrahim Yakoub-Agha C écile Borel Source Type: research

Intellectual disability and cancer in children: An analysis of the decision-making process
DISCUSSION: We propose three steps to guide the decision-making process in situations involving children with intellectual disability and cancer: 1/deeper understanding of the child through reinforced interactions with their caregivers, 2/better cross-boundary discussions, to improve the effectiveness of the multidisciplinary staff, and 3/more systematic ethical committees consultation.PMID:34176585 | DOI:10.1016/j.bulcan.2021.02.013 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 28, 2021 Category: Cancer & Oncology Authors: Marie-Th érèse Dangles Dominique Davous Gu énola Vialle Anne Auvrignon Elisabeth Angellier Franck Bourdeaut Source Type: research

Palliative care in hematopoietic stem-cell transplanted patients: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
The objective of this work is to propose recommendations to promote the implementation of palliative care into transplant units.PMID:34176584 | DOI:10.1016/j.bulcan.2021.01.019 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 28, 2021 Category: Cancer & Oncology Authors: Alice Polomeni Chlo é Prod'homme Malika Ainaoui Adeline Bellec Aur élie Berr Jacinthe Bonneau Amandine Charbonnier Val érie Coiteux Eva de Berranger Thomas Descamps Marion Gire Murielle Goncalves Agn ès Ruscassié Ibrahim Yakoub-Agha C écile Borel Source Type: research

Intellectual disability and cancer in children: An analysis of the decision-making process
DISCUSSION: We propose three steps to guide the decision-making process in situations involving children with intellectual disability and cancer: 1/deeper understanding of the child through reinforced interactions with their caregivers, 2/better cross-boundary discussions, to improve the effectiveness of the multidisciplinary staff, and 3/more systematic ethical committees consultation.PMID:34176585 | DOI:10.1016/j.bulcan.2021.02.013 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 28, 2021 Category: Cancer & Oncology Authors: Marie-Th érèse Dangles Dominique Davous Gu énola Vialle Anne Auvrignon Elisabeth Angellier Franck Bourdeaut Source Type: research

Actuality of conflicts of interests in medicine. From financial interests to the run for scientific publication
Bull Cancer. 2021 Jun 23:S0007-4551(21)00211-3. doi: 10.1016/j.bulcan.2021.04.013. Online ahead of print.ABSTRACTClinical practice and medical research can expose to several situations with risks of conflicts of interests. Such situations can induce attenuations of their primary professional interest in favor of, so-called, secondary interests, and leading to bias in their judgement and actions. In this area, if financial conflicts of interests are consistent and frequently dominant, intellectual conflicts of interests have to be analyzed and considered, like those amplified and even induced by the current tremendous compe...
Source: Bulletin du Cancer - June 27, 2021 Category: Cancer & Oncology Authors: Dominique Maraninchi Source Type: research

New European Medicines Agency approval: Tucatinib in association with trastuzumab and capecitabine for the treatment of HER2-positive metastatic breast cancer previously treated
Bull Cancer. 2021 Jun 22:S0007-4551(21)00175-2. doi: 10.1016/j.bulcan.2021.04.004. Online ahead of print.NO ABSTRACTPMID:34172272 | DOI:10.1016/j.bulcan.2021.04.004 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 26, 2021 Category: Cancer & Oncology Authors: Justine Bonnemort Audrey Bellesoeur Source Type: research

New European Medicines Agency approval: Tucatinib in association with trastuzumab and capecitabine for the treatment of HER2-positive metastatic breast cancer previously treated
Bull Cancer. 2021 Jun 22:S0007-4551(21)00175-2. doi: 10.1016/j.bulcan.2021.04.004. Online ahead of print.NO ABSTRACTPMID:34172272 | DOI:10.1016/j.bulcan.2021.04.004 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 26, 2021 Category: Cancer & Oncology Authors: Justine Bonnemort Audrey Bellesoeur Source Type: research

New European Medicines Agency approval: Tucatinib in association with trastuzumab and capecitabine for the treatment of HER2-positive metastatic breast cancer previously treated
Bull Cancer. 2021 Jun 22:S0007-4551(21)00175-2. doi: 10.1016/j.bulcan.2021.04.004. Online ahead of print.NO ABSTRACTPMID:34172272 | DOI:10.1016/j.bulcan.2021.04.004 (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - June 26, 2021 Category: Cancer & Oncology Authors: Justine Bonnemort Audrey Bellesoeur Source Type: research

Targeting the cyclin-dependent kinases 4/6 in advanced breast cancers
Bull Cancer. 2021 Jun 18:S0007-4551(21)00203-4. doi: 10.1016/j.bulcan.2021.04.007. Online ahead of print.ABSTRACTThe historical median survival of advanced luminal breast cancer does not exceed four years. The deciphering of the mechanisms of resistance to hormone therapy has led to the development of inhibitors of cyclin D dependent kinases (CDK4 and 6). Three drugs, palbociclib, ribociclib and abemaciclib, very similar pharmacologically, have been evaluated in the context of pivotal, randomized phase III trials. Strikingly and regardless of the endocrine therapy backbone, and in both hormone-sensitive and hormone-resista...
Source: Bulletin du Cancer - June 22, 2021 Category: Cancer & Oncology Authors: Florence Coussy Elise Deluche Barbara Pistilli Sylvain Ladoire Jean-Marc Ferrero Paul Cottu Source Type: research

Targeting the cyclin-dependent kinases 4/6 in advanced breast cancers
Bull Cancer. 2021 Jun 18:S0007-4551(21)00203-4. doi: 10.1016/j.bulcan.2021.04.007. Online ahead of print.ABSTRACTThe historical median survival of advanced luminal breast cancer does not exceed four years. The deciphering of the mechanisms of resistance to hormone therapy has led to the development of inhibitors of cyclin D dependent kinases (CDK4 and 6). Three drugs, palbociclib, ribociclib and abemaciclib, very similar pharmacologically, have been evaluated in the context of pivotal, randomized phase III trials. Strikingly and regardless of the endocrine therapy backbone, and in both hormone-sensitive and hormone-resista...
Source: Bulletin du Cancer - June 22, 2021 Category: Cancer & Oncology Authors: Florence Coussy Elise Deluche Barbara Pistilli Sylvain Ladoire Jean-Marc Ferrero Paul Cottu Source Type: research