[Which recent results in Oncology and Hematology will have an impact on our practices? The point of vue of Bulletin du Cancer editorial board].
The objective is to discuss results that change or reinforce the strategies in 2016 but also identify key information for our reflections in 2017. PMID: 28007296 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - December 19, 2016 Category: Cancer & Oncology Authors: Vignot S, André T, Gonçalves A, Guièze R, Magné N, Orbach D, Penel N, Thariat J, Wislez M, Bay JO Tags: Bull Cancer Source Type: research

Intra-arterial therapies for colorectal cancer liver metastases (radioembolization excluded).
Deschamps F Abstract During the past 20 years, advances in systemic therapies have improved overall survival of patients with Colorectal cancer Liver metastases (CRLM) from 6 to 24 months. By reaching CRLM via their preferential arterial vascularization, hepatic arterial infusion of chemotherapy (HAIC) has demonstrated improvement in response rate and deepness of response. Improvement in deepness of response is potentially helpful to convert no surgical patient to surgery. Recent HAIC regimens, including HAIC-FUDR plus systemic oxaliplatin/irinotecan, or HAIC-oxaliplatin plus systemic 5FU and cetuximab y...
Source: Bulletin du Cancer - December 16, 2016 Category: Cancer & Oncology Authors: de Baere T, Tselikas L, Boige V, Ducreux M, Malka D, Goéré D, Benahim E, Deschamps F Tags: Bull Cancer Source Type: research

[Evaluation of the immune infiltrate in breast cancer].
This article reviews elements of the immune response to cancer, methods of TIL analysis, evidence of TIL' prognostic and predictive value in the current breast cancer management as well as the perspectives for use of TIL' characteristics as biomarkers in breast cancer immunotherapy. PMID: 27986267 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - December 13, 2016 Category: Cancer & Oncology Authors: Radosevic-Robin N, Béguinot M, Penault-Llorca F Tags: Bull Cancer Source Type: research

[Incidence and risk factors for ifosfamide-related encephalopathy in sarcoma patients].
CONCLUSION: Ifosfamide administration must be given with caution in patients with poor performans status. A 4 to 5 days fractioned ifosfamide and leptomeningeal metastasis seems associated with increased risk for IRE, whatever the total administered dose. PMID: 27986268 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - December 13, 2016 Category: Cancer & Oncology Authors: Stern N, Sakji I, Defachelles AS, Lervat C, Ryckewaert T, Marliot G, Peugniez C, Deplanque D, Penel N Tags: Bull Cancer Source Type: research

Immunotherapy and patients treated for cancer with microsatellite instability.
We present a comprehensive overview of MSI phenotype, its biological landscape and current diagnostic methods. Then we focus on MSI as a predictive biomarker of response to immune checkpoint inhibition in the context of colorectal cancer and non-colorectal tumors. PMID: 27979364 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - December 12, 2016 Category: Cancer & Oncology Authors: Colle R, Cohen R, Cochereau D, Duval A, Lascols O, Lopez-Trabada D, Afchain P, Trouilloud I, Parc Y, Lefevre JH, Fléjou JF, Svrcek M, André T Tags: Bull Cancer Source Type: research

[Reappraisal role of locoregional radiation therapy in metastatic cancers].
te; N Abstract Recent innovations in oncology area helped to improve the prognosis of certain cancers including metastatic ones with a decrease in mortality. Recommendations describe the treatment of metastatic cancer as systemic therapy or complementary care and the role of locoregional treatment in the treatment plan only occurs in a palliative context. Currently, in the clinical practice, out of "the evidence based medicine", an early locoregional therapy (surgery or radiation therapy) can be proposed in several cases of metastatic cancers. The aim of the present review is to describe the role of the ...
Source: Bulletin du Cancer - December 9, 2016 Category: Cancer & Oncology Authors: Rancoule C, Pacaut-Vassal C, Vallard A, Mery B, Trone JC, El Meddeb Hamrouni A, Magné N Tags: Bull Cancer Source Type: research

[Care pathways before diagnosis in children and adolescents with malignancies].
J, Orbach D Abstract OBJECTIVE: to describe medical care pathways between first symptoms and first oncologic consultation in children and adolescents with solid cancers in order to analyze a possible relationship between delayed diagnosis and its potential consequences. METHODS: Retrospective study on patients aged less than 25 years at first consultation in the oncology department of pediatric, adolescent and young adult in Institut Curie during one year. Were collected data on cancer characteristics, components of care pathways, and sociodemographic parents' characteristics. RESULTS: Hundred and s...
Source: Bulletin du Cancer - December 7, 2016 Category: Cancer & Oncology Authors: Tatencloux S, Mosseri V, Papillard-Maréchal S, Mesples B, Pellegrino B, Belloy M, Jimènez I, Algret N, Levy D, Michon J, Orbach D Tags: Bull Cancer Source Type: research

[Big data and their perspectives in radiation therapy].
Abstract The concept of big data indicates a change of scale in the use of data and data aggregation into large databases through improved computer technology. One of the current challenges in the creation of big data in the context of radiation therapy is the transformation of routine care items into dark data, i.e. data not yet collected, and the fusion of databases collecting different types of information (dose-volume histograms and toxicity data for example). Processes and infrastructures devoted to big data collection should not impact negatively on the doctor-patient relationship, the general process of car...
Source: Bulletin du Cancer - November 30, 2016 Category: Cancer & Oncology Authors: Guihard S, Thariat J, Clavier JB Tags: Bull Cancer Source Type: research

[Carcinoma of unknown primary site: From necropsy to epigenetic analysis].
PMID: 27912891 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 29, 2016 Category: Cancer & Oncology Authors: Penel N Tags: Bull Cancer Source Type: research

[Mesocolic excision for colonic adenocarcinoma].
arc Y Abstract On the same principle than total mesorectal excision in rectal cancer, the effect of complete mesocolic excision on short and long-term outcomes is actually evaluated for colonic adenocarcinoma. This method, usually performed for left colectomy, offers a surgical specimen of higher quality, with a larger number of lymph nodes harvested. For right colectomy, surgical specifications make it less common complete mesocolic excision and conventional surgery offer comparable outcomes, as regards to postoperative morbidity and mortality rates. No differences are identified between laparoscopic and open sur...
Source: Bulletin du Cancer - November 29, 2016 Category: Cancer & Oncology Authors: Debove C, Lefèvre JH, Parc Y Tags: Bull Cancer Source Type: research

[Perioperative therapies in surgical non N2  non-small cell lung cancer].
[Perioperative therapies in surgical non N2 non-small cell lung cancer]. Bull Cancer. 2016 Nov 29;: Authors: Ruppert AM, Lavolé A, Assouad J, Cadranel J, Wislez M Abstract Platinum-based perioperative chemotherapy is actually the standard of care in stage II-IIIa non-small cell lung cancer (NSCLC). A benefit may also be seen in stage IB NSCLC with tumors of more than 4cm of diameter. Perioperative chemotherapy improves 5-year survival of 4 to 15%. This benefit is mainly proved by postoperative chemotherapy trials. Nevertheless, preoperative chemotherapy has advantages: a bet...
Source: Bulletin du Cancer - November 29, 2016 Category: Cancer & Oncology Authors: Ruppert AM, Lavolé A, Assouad J, Cadranel J, Wislez M Tags: Bull Cancer Source Type: research

[New applications for individual participant data meta-analyses of randomized trials].
This article aims at reviewing some of these new applications. Meta-analyses are increasingly used in economic evaluation, which implies new measure outcomes of the treatment effect, as well as in biomarkers evaluations thanks to their higher statistical power and the possibility to validate findings on independent data. This article also considers the perspectives opened up by new data sources, such as randomized trials registers, and data sharing policies. PMID: 27908441 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 28, 2016 Category: Cancer & Oncology Authors: Lueza B, Lacas B, Pignon JP, Paoletti X Tags: Bull Cancer Source Type: research

[Contribution and challenges of Big Data in oncology].
Abstract Since the first draft of the human genome sequence published in 2001, the cost of sequencing has dramatically decreased. The development of new technologies such as next generation sequencing led to a comprehensive characterization of a large number of tumors of various types as well as to significant advances in precision medicine. Despite the valuable information this technological revolution has allowed to produce, the vast amount of data generated resulted in the emergence of new challenges for the biomedical community, such as data storage, processing and mining. Here, we describe the contribution an...
Source: Bulletin du Cancer - November 25, 2016 Category: Cancer & Oncology Authors: Saintigny P, Foy JP, Ferrari A, Cassier P, Viari A, Puisieux A Tags: Bull Cancer Source Type: research

[Prostate cancer: To treat or not to treat?]
PMID: 27894505 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 25, 2016 Category: Cancer & Oncology Authors: Mazeron JJ Tags: Bull Cancer Source Type: research

[Usefulness of social and educational approach in adolescents and young adults with cancer: The Lille team's experience].
Abstract Within the second "Cancer plan" 2009-2013, the French national institute of cancer (INCa) recommended the implementation of programs dedicated to adolescents and youngs adults (AYA) with cancer. In this context and in parallel to the specific medical care developed for AYA, the Oscar-Lambret center created a psycho-social-educational team including among others a social worker (SW) and a special educational teacher (SET), offering multidisciplinary qualifications and views. The social approach, realized as a pair by SW-SET, takes into account every aspect of each AYA (family, academic, career/pr...
Source: Bulletin du Cancer - November 22, 2016 Category: Cancer & Oncology Authors: Jacquot J, Delbarre-Philippart M, Bricout H, Lervat C, Carbonnelle G, Leblond P, Defachelles AS, Penel N, Sudour-Bonnange H Tags: Bull Cancer Source Type: research

[Mitomycin-induced pulmonary veno-occlusive disease: A rare but severe complication].
PMID: 27884394 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 21, 2016 Category: Cancer & Oncology Authors: Montani D, Chaumais MC, Seferian A, Humbert M Tags: Bull Cancer Source Type: research

[Hodgkin and non-Hodgkin lymphoma of adolescents and young adults].
In conclusion, adolescent and young adult's lymphomas are very curable diseases but require a personalized management in onco-hematological units. PMID: 27866679 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 17, 2016 Category: Cancer & Oncology Authors: Garciaz S, Coso D, Brice P, Bouabdallah R Tags: Bull Cancer Source Type: research

ARLTS1, potential candidate gene in familial aggregation of hematological malignancies.
CONCLUSIONS: These results emphasize the fact that ARLTS1 gene mutations can be considered as a potential predisposing factor in familial hematological malignancies and other several cancer forms. PMID: 27866680 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 17, 2016 Category: Cancer & Oncology Authors: Hamadou WS, Besbes S, Mani R, Bourdon V, Ben Youssef Y, Achour B, Regaieg H, Eisinger F, Mari V, Gesta P, Dreyfus H, Bonadona V, Dugast C, Zattara H, Faivre L, Noguchi T, Khélif A, Sobol H, Soua Z Tags: Bull Cancer Source Type: research

[Psychosocial and developmental outcomes of TYAs with cancer: Are there any specific characteristics for the young adults?]
oni G Abstract During the last few years, specific support devices and even dedicated units for teenagers and young adults (TYAs - patients grouped in the 15-25 years age group) appeared in oncology. If the existing literature review allows identifying many written work related to the experience of cancer during adolescence, resources about "young adults" are not only far less abundant, but rarely give the definition of what is a "young adult". Based on this observation, it appears necessary, at this stage of our practice, to question the definition and psychosocial outcomes of those psych...
Source: Bulletin du Cancer - November 17, 2016 Category: Cancer & Oncology Authors: Leprince T, Sauveplane D, Ricadat E, Seigneur É, Marioni G Tags: Bull Cancer Source Type: research

[Adolescent and Young Adults (AYAS) brain tumor national Web conference. On behalf of ANOCEF, GO-AJA and SFCE societies].
CONCLUSION: Multidisciplinary Web conference for AYAs is feasible and increases the inclusion rate in protocols. It should be developed further. PMID: 27866682 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 17, 2016 Category: Cancer & Oncology Authors: Frappaz D, Sunyach MP, Le Rhun E, Blonski M, Laurence V, Bonneville Levard A, Loiseau H, Meyronnet D, Callies A, Laigle-Donadey F, Faure Conter C, au nom de l’ANOCEF, GO-AJA, de la SFCE Tags: Bull Cancer Source Type: research

[Which approach of therapeutic education (TE) for adolescents and young adults with cancer? Experience from the TE working group of "Go-AJA"].
CONCLUSION: Regardless of the care system, care workers dedicated to AYA with cancer should use TE-specific actions to reinforce treatment participation and therapeutic relationships. This active multidisciplinary TE working group dedicated to AYA with cancer elaborated TE programs by skilled multidisciplinary teams engaged in interactive educational actions. After this work of a national TE organization, more studies using methodological tools are still required to evaluate the impact of such implemented programs on the treatment results and the quality of life. PMID: 27863724 [PubMed - as supplied by publisher] (Sou...
Source: Bulletin du Cancer - November 15, 2016 Category: Cancer & Oncology Authors: Corradini N, Dagorne L, Retailleau M, Rédini F, Sudour-Bonnange H, Gofti-Laroche L, Le Rhun A, Gaspar N Tags: Bull Cancer Source Type: research

[What specific socialisation, social, educational and professional for teenagers and young adults with cancer?]
ltes français (GO-AJA) Abstract Socialisation, education, first jobs and autonomy are key steps to teenagers and young adults (TYA) integration into the society. The occurrence of a cancer in this population increases the difficulties. Although, suffering of cancer do affect TYA life journey at social, scholar and professional levels, from diagnosis to the after-cancer live and sometime forever, few studies exist in France. A national study on TYA with cancer (TYAC) social, scholar and professional pathways is on-going (ESPOIR-AJA). A national survey of the existing TYAC insertion support in 2013 by th...
Source: Bulletin du Cancer - November 15, 2016 Category: Cancer & Oncology Authors: Roesler C, Pautre I, Thirry D, Flores S, Chabbert C, Savre N, Pibarot M, Seveau MA, Dugas K, Rollin Z, Dumont S, Gaspar N, au nom du sous-groupe « Insertion » de groupe onco-hématologie adolescents et jeunes adultes français (GO-AJA) Tags: Bull Cancer Source Type: research

[MET receptor inhibition: Hope against resistance to targeted therapies?]
Abstract Overcoming the drug resistance remains a crucial issue in cancer treatment. For refractory patients, the use of MET receptor tyrosine kinase inhibitors seems to be hopeful. Indeed, important mechanisms underlying drug resistance argue for association of MET inhibitors with targeted therapies, both on first-line to prevent a primary resistance and on the second line to overcoming acquired resistance. Indeed, met gene amplification is the second most common alteration involved in acquired resistance to anti-epidermal growth factor receptor (EGFR) therapies in non-small cells lung cancer (NSCLC). Hypoxia, fo...
Source: Bulletin du Cancer - November 15, 2016 Category: Cancer & Oncology Authors: Hochart A, Leblond P, Le Bourhis X, Meignan S, Tulasne D Tags: Bull Cancer Source Type: research

[General and ethical considerations for the informed consent process: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
Abstract Informed consent is not restricted to clinical research and must be applied to high-risk care such as hematopoietic stem cell transplantation. If standardized informed consent might improve inequalities in medical practices between different transplantation centers, it is strongly recommended that it be adapted with an honest dialogue between physicians and patients and physicians and donors. In an attempt to harmonize clinical practices among French hematopoietic stem cell transplantation centers, the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) held its sixth annual ...
Source: Bulletin du Cancer - November 14, 2016 Category: Cancer & Oncology Authors: Thibert JB, Polomeni A, Yakoub-Agha I, Bordessoule D Tags: Bull Cancer Source Type: research

[Polymorphism in HLA and KIR genes and the impact on hematopoietic stem cell transplantation outcomes and unrelated donor selection: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
This article addresses the impact of HLA and KIR gene polymorphism on the outcome of the transplantation in order to optimize unrelated donor selection. PMID: 27855950 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 14, 2016 Category: Cancer & Oncology Authors: Dubois V, Brignier A, Elsermans V, Gagne K, Kennel A, Pedron B, Picard C, Ravinet A, Varlet P, Cesbron A, Delbos F, Yakoub-Agha I, Loiseau P Tags: Bull Cancer Source Type: research

[Improving diagnosis coding in the ProMise database: Guidelines of the Francophone society of bone marrow transplantation and cellular therapy (SFGM-TC)].
Abstract In the attempt to harmonize clinical practices between different centers belonging to the Francophone society of bone marrow transplantation and cellular therapy (SFGM-TC), our society set up the sixth annual series of workshops which brought together practitioners from all member centers and took place in September 2015 in Lille. Here, we report our recommendations regarding diagnosis and disease status coding in the ProMISe database used by the SFGM-TC. PMID: 27842859 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 11, 2016 Category: Cancer & Oncology Authors: Polge E, Bourgue F, Cuvelier M, Pires B, Hugon N, Laurent N, Leclerc N, Leroux S, Le Bars L, Marion S, Meziane Y, Moukhtari L, Renault M, Peffault de Latour R, Yakoub-Agha I, Raus N Tags: Bull Cancer Source Type: research

[Haploidentical hematopoietic stem cell transplantation: Guidelines from the Francophone society of marrow transplantation and cellular therapy (SFGM-TC)].
I, Rubio MT Abstract Haploidentical hematopoietic stem cell transplantation (HSCT) is being increasingly used due to improvement of the transplantation procedures allowing a reduction of graft-versus-host-disease (GVHD) and of transplant-related mortality (TRM). Such improvements have been particularly observed after administration of T-replete HSCT graft associated to an in vivo T cell depletion by the administration of high-doses of cyclophosphamide (HD-Cy) after transplantation. Here, we have analyzed the results of haplo-identical T replete HSC transplants, in particular, when performed with post-transplant HD...
Source: Bulletin du Cancer - November 11, 2016 Category: Cancer & Oncology Authors: Nguyen S, Chalandon Y, Lemarie C, Simon S, Masson D, Dhedin N, Suarez F, Renaud B, Charbonnier A, Yafour N, François S, Duléry R, Blaise D, Yakoub-Agha I, Rubio MT Tags: Bull Cancer Source Type: research

[Information and consent forms for hematopoietic stem cell transplantation donors and recipients: Guidelines from the Franchophone society of bone marrow transplantation and cellular therapy (SFGM-TC)].
Abstract Within the context of the SFGM-TC's 6th workshop series on the harmonization of clinical practices, our workshop proposes a standardization of the informed consent process for hematopoietic stem cell donors and recipients leading up to an autologous or allogenic transplantation. All informed consent was for bone marrow or peripheral stem cell donors, and mononuclear/lymphocyte donors according to usual procedures. The informed consent for autologous and allogenic related or unrelated adults and pediatric transplantation patients have been included. A first step has been conducted for collecting in ad...
Source: Bulletin du Cancer - November 11, 2016 Category: Cancer & Oncology Authors: Bruno B, Thibert JB, Bancillon N, Desbos A, Fawaz A, Fournier I, Genty C, Issarni D, Leveille S, Premel C, Polomeni A, Renault M, Tarillon S, Wallart A, Yakoub-Agha I, Bordessoule D Tags: Bull Cancer Source Type: research

[Hypofractionated radiotherapy of prostate adenocarcinoma: Towards a new standard?]
PMID: 27842862 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 11, 2016 Category: Cancer & Oncology Authors: Mazeron JJ, Magne N, Thariat J Tags: Bull Cancer Source Type: research

[Assessment and management of post-transplant iron overload: Guidelines of the Francophone Society of Marrow Transplantation and Cellular Therapy (SFGM-TC)].
Abstract To harmonize clinical practice in hematopoietic stem cell transplantation, the Francophone Society of Bone Marrow Transplantation and Cell Therapy (SFGM-TC) set up the sixth annual series of workshops which brought together practitioners from all member centers and took place in September 2015 in Lille. The main aim of this session was to describe the impact, evaluation and treatment of post-transplant iron overload. PMID: 27842863 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 11, 2016 Category: Cancer & Oncology Authors: Jaspers A, Bouhya S, Belaiche S, Chevallier P, Hermet E, Hospital-Gustems C, Michallet M, Rialland F, Samsonova O, Sirvent A, Yakoub-Agha I, Rohrlich PS, Beguin Y Tags: Bull Cancer Source Type: research

[Use of hypnosis in radiotherapy as an alternative to general anesthesia in pediatric radiation oncology].
This study aimed to evaluate the place of the rituals and/or hypnosis in pediatric in a reference center in pediatric radiation oncology in Rhône-Alpes Auvergne. METHODS: This observational study retrospectively collected data on AG in children
Source: Bulletin du Cancer - November 11, 2016 Category: Cancer & Oncology Authors: Claude L, Morelle M, Mancini S, Duncan A, Sebban H, Carrie C, Marec-Berard P Tags: Bull Cancer Source Type: research

[Cancer in adolescents and young adults in France: Epidemiology and pathways of care].
de cancers Abstract In adolescents and young adults (AYA), cancers are rare but represent the third significant cause of death. The aim of this paper was to investigate epidemiological data and pathways of care of AYA in France. During the 2000-2008 period, overall age-standardized incidence rates (ASR) were 254.1/10(6) in 15-24-year-olds. The most frequently diagnosed cancers in male AYA were malignant gonadal germ-cell tumors and Hodgkin's lymphoma, and were melanoma, thyroid carcinoma and Hodgkin's disease in females. The ASR appeared stable over time. During the 2000-2004 period, the 5-year overall survival f...
Source: Bulletin du Cancer - November 3, 2016 Category: Cancer & Oncology Authors: Desandes E, Lacour B, Clavel J, le Réseau français des registres de cancers Tags: Bull Cancer Source Type: research

[Systemic neoadjuvant therapy of luminal breast cancer in 2016].
Abstract Neoadjuvant systemic therapies have been extensively evaluated in luminal breast cancer. Conventional cytotoxic chemotherapy increases breast conservation rate, albeit with a low level of complete pathological response of uncertain clinical significance. Endocrine therapies allow similar clinical results with much less side effects. Biological criteria of response to endocrine therapies are still being defined. The neoadjuvant setting must be used for early development of new compounds and to further document biological mechanisms of sensitivity and resistance to treatments. PMID: 27817858 [PubMed - ...
Source: Bulletin du Cancer - November 3, 2016 Category: Cancer & Oncology Authors: Cottu PH Tags: Bull Cancer Source Type: research

[Lenvatinib in radioiodine refractory thyroid carcinomas].
In this study, patients treated with lenvatinib had a significant increase in progression-free survival (18.3 months vs. 3.6 months; HR=0.21; CI=0.14-0.31, P 
Source: Bulletin du Cancer - November 3, 2016 Category: Cancer & Oncology Authors: de la Fouchardiere C Tags: Bull Cancer Source Type: research

[Implementation of a nurse-driven educational program improves management of sorafenib's toxicities in hepatocellular carcinoma].
CONCLUSION: This study suggests a clinical benefit of EP, with a better toxicity's management of sorafenib, leading to less dose reduction. Different types of EP should be compared prospectively, focusing on quality of life. PMID: 27817860 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 3, 2016 Category: Cancer & Oncology Authors: Brunot A, M'Sadek A, Le Roy F, Duval M, Le Sourd S, Ventroux E, Crouzet L, Guillygomarc'h A, Boucher E, Lelievre N, Laguerre B, Edeline J Tags: Bull Cancer Source Type: research

[Fertility preservation in adolescents and young adults with cancer].
Abstract Fertility impairment due to treatments is a major concern for patients who have survived cancer in adolescence or as a young adult. The impact of cancer treatments on fertility depends on the age at treatments, types and cumulative doses of chemotherapy, radiation doses to organs at risk, and on surgeries conducted. Fertility preservation strategies have been developed for many years, and recently diversified thanks to advances in reproductive biology. In female adolescents and young adults, ovarian stimulation followed by oocyte (or embryo) vitrification, ovarian tissue cryopreservation, and sometimes oo...
Source: Bulletin du Cancer - November 3, 2016 Category: Cancer & Oncology Authors: Rousset-Jablonski C, Chevillon F, Dhedin N, Poirot C Tags: Bull Cancer Source Type: research

[Teenagers and young adults facing cancer: Specific issues].
sel N PMID: 27817862 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 3, 2016 Category: Cancer & Oncology Authors: Marec-Bérard P, Boissel N Tags: Bull Cancer Source Type: research

[The ConSoRe project supports the implementation of big data in oncology].
PMID: 27816168 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 2, 2016 Category: Cancer & Oncology Authors: Heudel P, Livartowski A, Arveux P, Willm E, Jamain C Tags: Bull Cancer Source Type: research

[Transfer of allogeneic stem cell transplant recipients to the intensive care unit: Guidelines from the Francophone society of marrow transplantation and cellular therapy (SFGM-TC)].
gha I Abstract Transferring a patient undergoing an allogeneic stem cell transplantation to the intensive care unit (ICU) is always a challenging situation on a medical and psychological point of view for the patient and his relatives as well as for the medical staff. Despite the progress in hematology and intensive care during the last decade, the prognosis of these patients admitted to the ICU remains poor and mortality is around 50 %. The harmonization working party of the SFGM-TC assembled hematologists and intensive care specialist in order to improve conditions and modalities of the transfer of a patien...
Source: Bulletin du Cancer - November 2, 2016 Category: Cancer & Oncology Authors: Moreau AS, Bourhis JH, Contentin N, Couturier MA, Delage J, Dumesnil C, Gandemer V, Hichri Y, Jost E, Platon L, Jourdain M, Pène F, Yakoub-Agha I Tags: Bull Cancer Source Type: research

[Nobel prizes in medicine 2016].
PMID: 27816170 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - November 2, 2016 Category: Cancer & Oncology Authors: Auberger P Tags: Bull Cancer Source Type: research

[Management of graft failure and erythroblastopenia in patients undergoing allogeneic hematopoietic stem cell transplantation: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
Abstract Success of allogeneic hematopoietic stem cells transplantation requires both the underlying disease eradication and satisfying reconstitution of hematopoiesis from donor cells. However, reconstitution delays, secondary development or persistence of cytopenia are regularly observed and are potential causes of failure after allogeneic transplantation. These graft dysfunctions should be distinguished from non-engraftment/engraftment failure. Although these situations are relatively common, there is no consensus in the literature for their management. During the workshop of the SFGM-TC, the working group prop...
Source: Bulletin du Cancer - October 31, 2016 Category: Cancer & Oncology Authors: Cornillon J, Sicre de Fontbrune F, Chantepie S, Coiteux V, Gauthier J, Masouridi-Levrat S, Pochon C, Terriou L, Yakoub-Agha I, Dalle JH Tags: Bull Cancer Source Type: research

[Feasibility and accuracy of day surgery: Review of 396 operated breast cancer patients].
CONCLUSION: Postoperative complication and readmissions are very low (
Source: Bulletin du Cancer - October 31, 2016 Category: Cancer & Oncology Authors: Laurent AC, Mouttet D, Renou M, Wintz L, Fourchotte V, Féron JG, Deloménie M, Kriegel I, Tardivon A, Lesur M, Mons P, Alran S Tags: Bull Cancer Source Type: research

Nursing young people with cancer: What is "different" about it?
Nursing young people with cancer: What is "different" about it? Bull Cancer. 2016 Oct 31;: Authors: Morgan S, Soanes L Abstract Nursing Adolescents and Young Adults (AYA) with cancer is a relatively new specialty, with much work having been undertaken across Europe. As this evolving specialty develops, nurses are required to develop networks, learn from each other and help to shape services across countries. Describing the cancer journey, this paper looks at the literature and, merging it with over 20years of experience, describes 'what is different' about looking after this group of young p...
Source: Bulletin du Cancer - October 31, 2016 Category: Cancer & Oncology Authors: Morgan S, Soanes L Tags: Bull Cancer Source Type: research

[How we harmonize HSCT clinical practices among the SFGM-TC centers].
Abstract In hematopoietic transplantation, clinical patient care is localized and practices differ from one country to another and even from center to center. International guidelines are not always well adapted to the evolution of daily clinical practice, and they do not address all issues, especially practical ones. Therefore, in the absence of well-established guidelines, each center tends to make do by developing local procedures. In the attempt to harmonize localized clinical practices between different centers belonging to the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC),...
Source: Bulletin du Cancer - October 31, 2016 Category: Cancer & Oncology Authors: Tipton R, Yakoub-Agha I Tags: Bull Cancer Source Type: research

[Modalities for preparation, cryopreservation, thawing of hematopoietic stem cells and precautions for infusion to patient: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
Abstract To date, despite an existing regulatory framework and standards, there are no true technical recommendations. A survey of 23 cell processing facilities (France, Belgium and Switzerland) has allowed to overview current practices according to cellular products specifications upon arrival at the facility, with modalities for their preparation prior to cryopreservation, storage, thawing and finally for infusion to patient. Data analysis shows great variability of collected volumes and cell concentrations in cellular products. Despite homogeneous practices for handling cells at the facility, methods vary ...
Source: Bulletin du Cancer - October 31, 2016 Category: Cancer & Oncology Authors: Boulanger F, Decot V, Bulliard G, Calmels B, Giraud C, Lacassagne MN, Magnani A, Pouthier F, Thibert JB, Tirefort Y, Yakoub-Agha I, Baudoux E Tags: Bull Cancer Source Type: research

[Nutritional management for patients hospitalized during allogeneic stem cell transplantation: Guidelines from the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
Abstract Allogeneic haematopoietic stem-cell transplantation is usually applied with success for patients with diseases involving bone marrow and associated with frequent and severe malnutrition. Denutrition is an independent survival factor and contribute to transplant-related mortality. Due to the heaviness of the treatment, this event is frequent. Before allogeneic transplantation, the nutritional statute should be evaluated. The adult or pediatric patient's evaluation modalities and nutritional needs are detailed in this paper. The administration modalities (enteral or parenteral) with doses are specifically p...
Source: Bulletin du Cancer - October 24, 2016 Category: Cancer & Oncology Authors: Bay JO, Dendoncker C, Angeli M, Biot T, Chikhi M, Combal C, Jouannic L, Kermeur G, Lopvet L, Marchand T, Schmitt S, Servais S, Yakoub-Agha I, Seguy D Tags: Bull Cancer Source Type: research

[National patient follow-up care logbook: Guidelines by the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)].
Abstract In an attempt to harmonize clinical practices among French hematopoietic stem cell transplantation centers, the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) held its sixth annual workshop series in September 2015 in Lille. This event brought together practitioners from across the country. Our article discusses the updates and modifications for the 2016 version of the national patient follow-up care logbook. PMID: 27776733 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - October 21, 2016 Category: Cancer & Oncology Authors: de Berranger E, Balcaen S, Ainaoui M, Bompoint C, Borel C, Chevallier N, de Bentzmann N, Denis V, Kerautret K, Godin S, Labat ML, Letort-Bertrand M, Porcheron S, Magro L, Yakoub-Agha I, Guiraud M Tags: Bull Cancer Source Type: research

[Surgical management of ovarian cancer: Trends in clinical practice].
p F Abstract Surgery has evolved as a mainstay of the management of ovarian cancer since evidence of the major benefit of complete surgery, i.e. achieving complete resection of the disease without visible macroscopic residue in a comprehensively explored abdominal cavity, has been made available. This objective may be difficult to complete in case of advanced ovarian cancer, as it requires the use of advanced techniques of peritoneal and visceral surgery, in the setting of adapted perioperative care, generally in institutions where the caseload is sufficient to ensure an appropriate surgical experience, and where ...
Source: Bulletin du Cancer - October 18, 2016 Category: Cancer & Oncology Authors: Querleu D, Meurette J, Daraï E, Morice P, Planchamp F Tags: Bull Cancer Source Type: research

[Pediatric ependymomas: Current diagnosis and therapy].
Abstract Ependymomas represent 10% of pediatric brain tumors. In the recent WHO 2016 classification, pathology is enriched by localization and molecular biology. Whatever the age, total removal by one or several looks when required remains a major prognostic factor. In children, focal radiation remains a standard, while the role of chemotherapy is matter of randomized studies. In infants, front line chemotherapy is the standard. Inclusion in the SIOP ependymoma II protocol is encouraged. In case of relapse, further surgery and radiation are advised, while inclusion in innovative trials including re-irradiatio...
Source: Bulletin du Cancer - October 4, 2016 Category: Cancer & Oncology Authors: Frappaz D, Vasiljevic A, Beuriat PA, Alapetite C, Grill J, Szathmari A, Faure-Conter C Tags: Bull Cancer Source Type: research

[The use of the G8 score for the patient of more than 75years old in digestive surgery for cancer].
PMID: 27712831 [PubMed - as supplied by publisher] (Source: Bulletin du Cancer)
Source: Bulletin du Cancer - October 3, 2016 Category: Cancer & Oncology Authors: Sabbagh C, Cosse C, Fournier R, Carola E, Chauffert B, Dumesnil R, Regimbeau JM Tags: Bull Cancer Source Type: research