Incidence and Management of Radiation Cystitis After Pelvic Radiotherapy for Prostate Cancer: Analysis from a National Database
To determine the incidence of radiation cystitis on Prostate Cancer (PCa) patients undergoing pelvic radiotherapy (RT), evaluating the most used management strategies, and identifying potential risk factors associated with the development of this condition. (Source: Urology)
Source: Urology - April 28, 2024 Category: Urology & Nephrology Authors: Eugenio Bologna, Leslie Claire Licari, Antonio Franco, Francesco Ditonno, Celeste Manfredi, Cosimo De Nunzio, Alessandro Antonelli, Marco De Sio, Christopher Coogan, Srinivas Vourganti, Costantino Leonardo, Giuseppe Simone, Riccardo Autorino Source Type: research
Contemporary validation of cT1a vs. cT1b substaging of incidental prostate cancer
ConclusionThe historical subclassification of cT1a vs. cT1b in incidental PCa patients displayed a strong ability to discriminate CSS in contemporary GS 7 and GS ≥ 8 patients who underwent NLT. However, no statistically significant difference was recorded in actively treated patients. In consequence, the importance of the current substage stratification predominantly applies to GS ≥ 8 patients who undergo a non-active treatment approach. (Source: World Journal of Urology)
Source: World Journal of Urology - April 28, 2024 Category: Urology & Nephrology Source Type: research
Cancers, Vol. 16, Pages 1717: Applications of Urinary Extracellular Vesicles in the Diagnosis and Active Surveillance of Prostate Cancer
Cooper
Prostate cancer is the most common non-cutaneous cancer among men in the UK, causing significant health and economic burdens. Diagnosis and risk prognostication can be challenging due to the genetic and clinical heterogeneity of prostate cancer as well as uncertainties in our knowledge of the underlying biology and natural history of disease development. Urinary extracellular vesicles (EVs) are microscopic, lipid bilayer defined particles released by cells that carry a variety of molecular cargoes including nucleic acids, proteins and other molecules. Urine is a plentiful source of prostate-derived EVs. In this...
Source: Cancers - April 28, 2024 Category: Cancer & Oncology Authors: Stephanie F. Smith Daniel S. Brewer Rachel Hurst Colin S. Cooper Tags: Review Source Type: research
Contrast Agent Dynamics Determine Radiomics Profiles in Oncologic Imaging
CONCLUSIONS: CT and MRI radiomics features in both prostate and lung tumors are significantly affected by interindividual differences in contrast agent dynamics.PMID:38672601 | PMC:PMC11049400 | DOI:10.3390/cancers16081519 (Source: Nuklearmedizin)
Source: Nuklearmedizin - April 27, 2024 Category: Radiology Authors: Martin L Watzenboeck Lucian Beer Daria Kifjak Sebastian R öhrich Benedikt H Heidinger Florian Prayer Ruxandra-Iulia Milos Paul Apfaltrer Georg Langs Pascal A T Baltzer Helmut Prosch Source Type: research
Lectin-nanoparticle concept for free PSA glycovariant providing superior cancer specificity
CONCLUSIONS: Due to Eu-nanoparticles and a dense fPSA capture spot, the fPSAMGLGV identifies an fPSA subform with the highest cancer specificity compared to the four conventional kallikreins.PMID:38677453 | DOI:10.1016/j.cca.2024.119689 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 27, 2024 Category: Chemistry Authors: H Kekki I Montoya Perez P Taimen P J Bostr öm K Gidwani K Pettersson Source Type: research
Contrast Agent Dynamics Determine Radiomics Profiles in Oncologic Imaging
CONCLUSIONS: CT and MRI radiomics features in both prostate and lung tumors are significantly affected by interindividual differences in contrast agent dynamics.PMID:38672601 | PMC:PMC11049400 | DOI:10.3390/cancers16081519 (Source: Nuklearmedizin)
Source: Nuklearmedizin - April 27, 2024 Category: Radiology Authors: Martin L Watzenboeck Lucian Beer Daria Kifjak Sebastian R öhrich Benedikt H Heidinger Florian Prayer Ruxandra-Iulia Milos Paul Apfaltrer Georg Langs Pascal A T Baltzer Helmut Prosch Source Type: research
Lectin-nanoparticle concept for free PSA glycovariant providing superior cancer specificity
CONCLUSIONS: Due to Eu-nanoparticles and a dense fPSA capture spot, the fPSAMGLGV identifies an fPSA subform with the highest cancer specificity compared to the four conventional kallikreins.PMID:38677453 | DOI:10.1016/j.cca.2024.119689 (Source: Clinical Prostate Cancer)
Source: Clinical Prostate Cancer - April 27, 2024 Category: Cancer & Oncology Authors: H Kekki I Montoya Perez P Taimen P J Bostr öm K Gidwani K Pettersson Source Type: research
Lectin-nanoparticle concept for free PSA glycovariant providing superior cancer specificity
CONCLUSIONS: Due to Eu-nanoparticles and a dense fPSA capture spot, the fPSAMGLGV identifies an fPSA subform with the highest cancer specificity compared to the four conventional kallikreins.PMID:38677453 | DOI:10.1016/j.cca.2024.119689 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 27, 2024 Category: Chemistry Authors: H Kekki I Montoya Perez P Taimen P J Bostr öm K Gidwani K Pettersson Source Type: research
Contrast Agent Dynamics Determine Radiomics Profiles in Oncologic Imaging
CONCLUSIONS: CT and MRI radiomics features in both prostate and lung tumors are significantly affected by interindividual differences in contrast agent dynamics.PMID:38672601 | PMC:PMC11049400 | DOI:10.3390/cancers16081519 (Source: Nuklearmedizin)
Source: Nuklearmedizin - April 27, 2024 Category: Radiology Authors: Martin L Watzenboeck Lucian Beer Daria Kifjak Sebastian R öhrich Benedikt H Heidinger Florian Prayer Ruxandra-Iulia Milos Paul Apfaltrer Georg Langs Pascal A T Baltzer Helmut Prosch Source Type: research
Prostate Cancer Radioligand Therapy
Prostate cancer is the most common malignancy in men worldwide, with an estimated 174,650 new cases per year in the United States, and the second cancer-related cause of death, after lung cancer, with 31,620 deaths per year. While the 5 year survival rate for prostate cancer in patients without metastatic spread is nearly 100%, those with distant metastases have 5 year survival rates of approximately 30%. Initial diagnosis and assessment are based on PSA levels, Gleason score (derived from prostate biopsy), and advanced imaging modalities, including prostate MR imaging and PSMA-PET/computed tomography in patients with high...
Source: PET Clinics - April 27, 2024 Category: Radiology Authors: Yaniv Yechiel, Alexandre Chicheportiche, Zohar Keidar, Simona Ben-Haim Source Type: research
Predictive value of magnetic resonance imaging diffusion parameters using artificial intelligence in low-and intermediate-risk prostate cancer patients treated with stereotactic ablative radiotherapy: A pilot study
To investigate the predictive value of the pre-treatment diffusion parameters of diffusion-weighted magnetic resonance imaging (DW-MRI) using artificial intelligence (AI) for prostate-specific antigen (PSA) response in patients with low- and intermediate-risk prostate cancer (PCa) treated with stereotactic ablative radiotherapy (SABR). (Source: Radiography)
Source: Radiography - April 27, 2024 Category: Radiology Authors: A. Kedves, M. Akay, Y. Akay, K. Kisiv án, C. Glavák, Á. Miovecz, Á. Schiffer, Z. Kisander, A. Lőrincz, A. Szőke, B. Sánta, O. Freihat, D. Sipos, Á. Kovács, F. Lakosi Source Type: research
Editorial comment on “Reevaluating ‘Top-Down’ HoLEP: the case for anterior fibromuscular stroma as a surgical landmark”
Prostate Cancer and Prostatic Diseases, Published online: 27 April 2024; doi:10.1038/s41391-024-00842-yEditorial comment on “Reevaluating ‘Top-Down’ HoLEP: the case for anterior fibromuscular stroma as a surgical landmark” (Source: Prostate Cancer and Prostatic Diseases)
Source: Prostate Cancer and Prostatic Diseases - April 27, 2024 Category: Urology & Nephrology Authors: Hazem Elmansy Source Type: research
Identification of potential targetable genes in papillary, follicular, and anaplastic thyroid carcinoma using bioinformatics analysis
ConclusionsThe findings unravel potential biomarkers and therapeutic targets of thyroid carcinomas. (Source: Endocrine)
Source: Endocrine - April 27, 2024 Category: Endocrinology Source Type: research
Antibody-Drug Conjugates in the Treatment of Genitourinary Cancers: An Updated Review of Data
In this study, we have thoroughly completed a narrative review of the current literature and summarized preclinical studies and clinical trials that evaluated the utility, activity, and toxicity of ADCs in GU cancers, the prospects of ADC development, and the ongoing clinical trials. Prospective clinical trials, retrospective studies, case reports, and scoping reviews were included.PMID:38668075 | PMC:PMC11049516 | DOI:10.3390/curroncol31040172 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Prathana Nathan Adnan Rajeh Meh Noor Gabriel Boldt Ricardo Fernandes Source Type: research
