Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) MRI as a Response Monitoring Tool to Neoadjuvant Abiraterone
Conditions: High Risk Prostate Carcinoma; Prostate Cancer Interventions: Drug: Abiraterone acetate; Drug: Prednisone; Drug: Hyperpolarized [1-13C] pyruvate (HP 13C); Procedure: Magnetic Resonance Imaging (MRI); Procedure: Non-investigational radical prostatectomy (RP); Procedure: Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) PET/Computerized tomography (CT) Sponsors: Ivan de Kouchkovsky, MD Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials
A Phase 1/2 Study of 177Lu-NYM032 Injection in mCRPC
Conditions: Metastatic Castration-resistant Prostate Cancer Interventions: Drug: 177Lu-NYM032 injection Sponsors: Norroy Bioscience Co., LTD Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 25, 2024 Category: Research Source Type: clinical trials
Study of ACE-86225106 to Treat Patients With Advanced Solid Tumors
Conditions: Solid Tumor, Adult; BRCA1 Mutation; BRCA2 Mutation; Ovarian Cancer; Breast Cancer; Prostate Cancer Interventions: Drug: ACE-86225106 tablet Sponsors: Acerand Therapeutics (Shanghai) Limited Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials
Real-World Clinical Experience of Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Olaparib + Abiraterone (PROceed)
Conditions: Metastatic Castration-resistant Prostate Cancer Sponsors: AstraZeneca; Merck Sharp& Dohme LLC Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials
Choline Metabolites in People With Prostate Cancer and Those With Benign Hyperplasia
Conditions: Primary Prostate Urothelial Cancer; Benign Prostatic Hyperplasia Interventions: Other: Plasma concentration of choline Sponsors: Universit ät des Saarlandes Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2024 Category: Research Source Type: clinical trials
NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.
Conditions: Metastatic Neuroendocrine Prostate Cancer Interventions: Drug: [68Ga]Ga-PSMA-11; Drug: [68Ga]GA-DOTA-TATE; Drug: [68Ga]Ga-NeoB; Drug: [177Lu]Lu-PSMA-617; Drug: [177Lu]Lu-DOTA-TATE; Drug: [177Lu]Lu-NeoB; Drug: L-Lysine HCl-L-Arginine HCl, 2.5 %,; Drug: Gonadotropin-releasing hormone (GnRH) analogues; Drug: GnRH antagonists; Drug: Antiemetics& antinauseants; Drug: Metoclopramide Sponsors: Novartis Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2024 Category: Research Source Type: clinical trials
Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial
Conditions: Recurrent Castration-Sensitive Prostate Carcinoma; Stage IVB Prostate Cancer AJCC v8; Recurrent Prostate Cancer; Castration-resistant Prostate Cancer Interventions: Drug: Abiraterone; Drug: Apalutamide; Procedure: Biospecimen Collection; Procedure: Bone Scan; Procedure: Computed Tomography; Drug: Darolutamide; Drug: Degarelix; Drug: Enzalutamide; Drug: Goserelin; Drug: Histrelin; Drug: Leuprolide; Procedure: Magnetic Resonance Imaging; Other: Patient Observation; Procedure: Positron Emission Tomography; Drug: Prednisone; Other: Questionnaire Administration; Drug: Relugolix; Radiation: Stereotactic Body Radiatio...
Source: ClinicalTrials.gov - April 23, 2024 Category: Research Source Type: clinical trials
Choline Metabolites in Men With Prostate Cancer and Those With Benign Hyperplasia
Conditions: Primary Prostate Urothelial Cancer; Benign Prostatic Hyperplasia Sponsors: Universit ät des Saarlandes Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 23, 2024 Category: Research Source Type: clinical trials
GU-01: Glycyrrhizin in Prostate Cancer
Conditions: Prostate Cancer Interventions: Drug: Glycyrrhizin; Other: Glycyrrhizin; Other: Observation Sponsors: University of Illinois at Chicago Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials
GU-01: Glycyrrhizin in Prostate Cancer: A Window-of-Opportunity Clinical and Translational Trial
Conditions: Prostate Cancer Interventions: Drug: Glycyrrhizin; Other: Glycyrrhizin; Other: Observation Sponsors: University of Illinois at Chicago Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials
Clinical Evaluation of 177Lu-DansyI-PSMA (LNC1011) in Patients With Metastatic Castration-Resistant Prostate Cancer
Conditions: Metastatic Castration-resistant Prostate Cancer, mCRPC Interventions: Drug: 177Lu-Dansyl-PSMA radioligand therapy Sponsors: The First Affiliated Hospital of Xiamen University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 22, 2024 Category: Research Source Type: clinical trials
ES-HIFU, Prospective Data Collection of Patients Treated With Partial Gland HIFU Ablation for Prostate Cancer
Conditions: Prostate Cancer Interventions: Device: FocalOne Sponsors: EDAP TMS S.A. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 19, 2024 Category: Research Source Type: clinical trials
Is the HIFEM Procedure an Effective Treatment for Men With Post-prostatectomy Incontinence?
Conditions: Prostate Cancer; Incontinence; Pelvic Floor Muscle Weakness Interventions: Device: HIFEM Sponsors: Kirsehir Ahi Evran Universitesi Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 18, 2024 Category: Research Source Type: clinical trials
Risk Stratified De-escalated Hormone Therapy With Radiation Therapy for the Treatment Prostate Cancer
Conditions: Oligometastatic Prostate Carcinoma; Prostate Adenocarcinoma Interventions: Drug: Abiraterone Acetate; Procedure: Biospecimen Collection; Procedure: Computed Tomography; Biological: Gonadotropin-releasing Hormone Analog; Procedure: Magnetic Resonance Imaging; Procedure: Positron Emission Tomography; Other: Questionnaire Administration; Radiation: Radiation Therapy Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 17, 2024 Category: Research Source Type: clinical trials
PRORAD-5 PROstate RADiation in 5 Fractions: Phase Ib Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer
Conditions: Advanced Prostate Cancer Interventions: Device: Stereotactic Body Radiation Therapy Sponsors: M.D. Anderson Cancer Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials
