SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps
CONCLUSION: SerpinB3/B4 expression is upregulated in nasal mucosa of CRSwNP patients. SerpinB3/B4 may play an anti-inflammatory role in CRSwNP by inhibiting the expression of epithelial cell-derived CXCL8/IL-8.PMID:38550710 | PMC:PMC10978078 | DOI:10.1155/2024/8553447 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - March 29, 2024 Category: Allergy & Immunology Authors: Xiangting Bu Ming Wang Jing Yuan Jing Song Ge Luan Jiaqi Yu Yang Wang Ying Li Chengshuo Wang Luo Zhang Source Type: research
Breaking the neural code of a cnidarian: Learning principles of neuroscience from the "vulgar" Hydra
Curr Opin Neurobiol. 2024 Mar 28;86:102869. doi: 10.1016/j.conb.2024.102869. Online ahead of print.ABSTRACTThe cnidarian Hydra vulgaris is a small polyp with a nervous system of few hundred neurons belonging to a dozen cell types, organized in two nerve nets without cephalization or ganglia. Using this simple neural "chassis", Hydra can maintain a stable repertoire of behaviors, even performing complex fixed-action patterns, such as somersaulting and feeding. The ability to image the activity of Hydra's entire neural and muscle tissue has revealed that Hydra's nerve nets are divided into coactive ensembles of neurons, asso...
Source: Current Opinion in Neurobiology - March 29, 2024 Category: Neurology Authors: Rafael Yuste Source Type: research
Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology
CONCLUSION: Novel BMs such as Gal10 from serum EVs reflect disease pathophysiology in BA and may represent a new target for liquid biopsy approaches.PMID:38551536 | DOI:10.1016/j.jaci.2023.12.030 (Source: Genomics Proteomics ...)
Source: Genomics Proteomics ... - March 29, 2024 Category: Genetics & Stem Cells Authors: Hanako Yoshimura Yoshito Takeda Yuya Shirai Makoto Yamamoto Daisuke Nakatsubo Saori Amiya Takatoshi Enomoto Reina Hara Yuichi Adachi Ryuya Edahiro Moto Yaga Kentaro Masuhiro Taro Koba Miho Itoh-Takahashi Mana Nakayama So Takata Yuki Hosono Sho Obata Masay Source Type: research
SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps
CONCLUSION: SerpinB3/B4 expression is upregulated in nasal mucosa of CRSwNP patients. SerpinB3/B4 may play an anti-inflammatory role in CRSwNP by inhibiting the expression of epithelial cell-derived CXCL8/IL-8.PMID:38550710 | PMC:PMC10978078 | DOI:10.1155/2024/8553447 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - March 29, 2024 Category: Allergy & Immunology Authors: Xiangting Bu Ming Wang Jing Yuan Jing Song Ge Luan Jiaqi Yu Yang Wang Ying Li Chengshuo Wang Luo Zhang Source Type: research
Breaking the neural code of a cnidarian: Learning principles of neuroscience from the "vulgar" Hydra
Curr Opin Neurobiol. 2024 Mar 28;86:102869. doi: 10.1016/j.conb.2024.102869. Online ahead of print.ABSTRACTThe cnidarian Hydra vulgaris is a small polyp with a nervous system of few hundred neurons belonging to a dozen cell types, organized in two nerve nets without cephalization or ganglia. Using this simple neural "chassis", Hydra can maintain a stable repertoire of behaviors, even performing complex fixed-action patterns, such as somersaulting and feeding. The ability to image the activity of Hydra's entire neural and muscle tissue has revealed that Hydra's nerve nets are divided into coactive ensembles of neurons, asso...
Source: Current Opinion in Neurobiology - March 29, 2024 Category: Neurology Authors: Rafael Yuste Source Type: research
Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology
Bronchial asthma (BA) is a common chronic disease affecting 300 million people globally,1 with up to 10% of patients presenting with severe BA. BA is a complex respiratory disease characterized by airway inflammation, bronchial hyperresponsiveness, and variable airflow limitation2 and is often complicated by rhinitis and chronic rhinosinusitis with nasal polyps (CRSwNP).3 BA is heterogenous, with variable phenotypes and endotypes, and therefore can be difficult to diagnose and treat.4 While the one-airway –one-disease hypothesis proposed that the upper and lower airways share a similar pathophysiology,5 the mechanisms un...
Source: Journal of Allergy and Clinical Immunology - March 29, 2024 Category: Allergy & Immunology Authors: Hanako Yoshimura, Yoshito Takeda, Yuya Shirai, Makoto Yamamoto, Daisuke Nakatsubo, Saori Amiya, Takatoshi Enomoto, Reina Hara, Yuichi Adachi, Ryuya Edahiro, Moto Yaga, Kentaro Masuhiro, Taro Koba, Miho Itoh-Takahashi, Mana Nakayama, So Takata, Yuki Hosono Source Type: research
Eosinophil-associated diseases: the allergist's and clinical immunologist's perspective
Eur Ann Allergy Clin Immunol. 2024 Mar 28. doi: 10.23822/EurAnnACI.1764-1489.339. Online ahead of print.ABSTRACTEosinophil-associated diseases (EADs) refer to heterogeneous conditions in which eosinophils are believed to play critical pathological roles. They encompass common respiratory conditions, such as asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), less common primary eosinophilic disorders of gastrointestinal tract, and rare conditions including eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES). A literature search was carried out in January 2024 in the MEDLINE and ...
Source: European Annals of Allergy and Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: A M Marra C M Rossi M A Piga G Moroncini M B Bil ò Source Type: research
Can MRI Accurately Diagnose and Stage Endometrial Adenocarcinoma?
Conclusions: Our data confirm the high accuracy of MRI in the diagnosis and local staging of endometrial carcinoma. The information provided by MRI has an important role in planning the treatment and the prognosis of the patients.PMID:38541238 | DOI:10.3390/medicina60030512 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Ramona-Andreea Rizescu Iulia Alecsandra S ălcianu Alexandru Șerbănoiu Radu Tudor Ion Lucian Mihai Florescu Ioana-Andreea Gheonea Gheorghe Iana Ana Magdalena Bratu Source Type: research
Eosinophil-associated diseases: the allergist's and clinical immunologist's perspective
Eur Ann Allergy Clin Immunol. 2024 Mar 28. doi: 10.23822/EurAnnACI.1764-1489.339. Online ahead of print.ABSTRACTEosinophil-associated diseases (EADs) refer to heterogeneous conditions in which eosinophils are believed to play critical pathological roles. They encompass common respiratory conditions, such as asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), less common primary eosinophilic disorders of gastrointestinal tract, and rare conditions including eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES). A literature search was carried out in January 2024 in the MEDLINE and ...
Source: European Annals of Allergy and Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: A M Marra C M Rossi M A Piga G Moroncini M B Bil ò Source Type: research
Can MRI Accurately Diagnose and Stage Endometrial Adenocarcinoma?
Conclusions: Our data confirm the high accuracy of MRI in the diagnosis and local staging of endometrial carcinoma. The information provided by MRI has an important role in planning the treatment and the prognosis of the patients.PMID:38541238 | PMC:PMC10971866 | DOI:10.3390/medicina60030512 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Ramona-Andreea Rizescu Iulia Alecsandra S ălcianu Alexandru Șerbănoiu Radu Tudor Ion Lucian Mihai Florescu Ioana-Andreea Gheonea Gheorghe Iana Ana Magdalena Bratu Source Type: research
Eosinophil-associated diseases: the allergist's and clinical immunologist's perspective
Eur Ann Allergy Clin Immunol. 2024 Mar 28. doi: 10.23822/EurAnnACI.1764-1489.339. Online ahead of print.ABSTRACTEosinophil-associated diseases (EADs) refer to heterogeneous conditions in which eosinophils are believed to play critical pathological roles. They encompass common respiratory conditions, such as asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), less common primary eosinophilic disorders of gastrointestinal tract, and rare conditions including eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES). A literature search was carried out in January 2024 in the MEDLINE and ...
Source: European Annals of Allergy and Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: A M Marra C M Rossi M A Piga G Moroncini M B Bil ò Source Type: research
Can MRI Accurately Diagnose and Stage Endometrial Adenocarcinoma?
Conclusions: Our data confirm the high accuracy of MRI in the diagnosis and local staging of endometrial carcinoma. The information provided by MRI has an important role in planning the treatment and the prognosis of the patients.PMID:38541238 | PMC:PMC10971866 | DOI:10.3390/medicina60030512 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Ramona-Andreea Rizescu Iulia Alecsandra S ălcianu Alexandru Șerbănoiu Radu Tudor Ion Lucian Mihai Florescu Ioana-Andreea Gheonea Gheorghe Iana Ana Magdalena Bratu Source Type: research
Eosinophil-associated diseases: the allergist's and clinical immunologist's perspective
Eur Ann Allergy Clin Immunol. 2024 Mar 28. doi: 10.23822/EurAnnACI.1764-1489.339. Online ahead of print.ABSTRACTEosinophil-associated diseases (EADs) refer to heterogeneous conditions in which eosinophils are believed to play critical pathological roles. They encompass common respiratory conditions, such as asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), less common primary eosinophilic disorders of gastrointestinal tract, and rare conditions including eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES). A literature search was carried out in January 2024 in the MEDLINE and ...
Source: European Annals of Allergy and Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: A M Marra C M Rossi M A Piga G Moroncini M B Bil ò Source Type: research
Can MRI Accurately Diagnose and Stage Endometrial Adenocarcinoma?
Conclusions: Our data confirm the high accuracy of MRI in the diagnosis and local staging of endometrial carcinoma. The information provided by MRI has an important role in planning the treatment and the prognosis of the patients.PMID:38541238 | PMC:PMC10971866 | DOI:10.3390/medicina60030512 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Ramona-Andreea Rizescu Iulia Alecsandra S ălcianu Alexandru Șerbănoiu Radu Tudor Ion Lucian Mihai Florescu Ioana-Andreea Gheonea Gheorghe Iana Ana Magdalena Bratu Source Type: research
Eosinophil-associated diseases: the allergist's and clinical immunologist's perspective
Eur Ann Allergy Clin Immunol. 2024 Mar 28. doi: 10.23822/EurAnnACI.1764-1489.339. Online ahead of print.ABSTRACTEosinophil-associated diseases (EADs) refer to heterogeneous conditions in which eosinophils are believed to play critical pathological roles. They encompass common respiratory conditions, such as asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), less common primary eosinophilic disorders of gastrointestinal tract, and rare conditions including eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES). A literature search was carried out in January 2024 in the MEDLINE and ...
Source: European Annals of Allergy and Clinical Immunology - March 28, 2024 Category: Allergy & Immunology Authors: A M Marra C M Rossi M A Piga G Moroncini M B Bil ò Source Type: research
