Benralizumab in Severe Eosinophilic Asthma and Chronic Rhinosinusitis with Nasal Polyps: The Real-World, Multi-Country RANS Observational Study
(Source: Journal of Asthma and Allergy)
Source: Journal of Asthma and Allergy - April 5, 2024 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Standardised training for endoscopic mucosal resection of large non-pedunculated colorectal polyps to reduce recurrence (*STAR-LNPCP study): a multicentre cluster randomised trial
Conclusion
A compact standardised EMR training for LNPCPs significantly reduced recurrences in community hospitals. This strongly argues for a national dedicated training programme for endoscopists performing EMR of ≥20 mm LNPCPs. Interestingly, in sensitivity analysis, this benefit was limited for LNPCPs ≥40 mm.
Trial registration number
NTR7477. (Source: Gut)
Source: Gut - April 5, 2024 Category: Gastroenterology Authors: Meulen, L. W. T., Bogie, R. M. M., Siersema, P. D., Winkens, B., Vlug, M. S., Wolfhagen, F. H. J., Baven-Pronk, M., van der Voorn, M., Schwartz, M. P., Vogelaar, L., de Vos tot Nederveen Cappel, W. H., Seerden, T. C. J., Hazen, W. L., Schrauwen, R. W. M., Tags: Gut Endoscopy Source Type: research
New AI model for neoplasia detection and characterisation in inflammatory bowel disease
Message Endoscopic neoplasia detection in inflammatory bowel disease (IBD) remains challenging. We developed and validated a novel artificial intelligence (AI) model for lesion detection and characterisation in 478 images from 30 patients with IBD, 10 of whom had a total of 25 neoplastic lesions (including 8 sessile serrated polyps); sensitivity and specificity for lesion detection were 93.5% and 80.6%, respectively. The IBD model was then further validated during a real-time endoscopic assessment of a further 30 consecutive patients with 25 neoplastic lesions found in 11/30 of them and achieved lesion detection rate, lesi...
Source: Gut - April 5, 2024 Category: Gastroenterology Authors: Abdelrahim, M., Siggens, K., Iwadate, Y., Maeda, N., Htet, H., Bhandari, P. Tags: Gut Endoscopy news Source Type: research
Sessile serrated polyp detection rates after fecal immunochemical test or multitarget stool DNA test: Systematic review and meta-analysis
Conclusions FIT-DNA outperformed FIT in both SSP and ASP detection including FIT with a lower threshold cutoff of >10 ug/g. Further comparative studies are needed to assess the impact of our findings on colorectal cancer reduction.
[...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Endoscopy International Open)
Source: Endoscopy International Open - April 5, 2024 Category: Gastroenterology Authors: Garg, Rajat Burke, Carol A. Aggarwal, Manik Macaron, Carole Singh, Amandeep Kim, Michelle K. Regueiro, Miguel Amit, Bhatt Chahal, Prabhleen Garg, Shashank Tags: Review Source Type: research
Association between endoscopist adenoma detection rate and serrated polyp detection: Retrospective analysis of over 200,000 screening colonoscopies
Conclusions This study shows that endoscopists with higher ADR detect significantly more serrated lesions than those with a lower ADR. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Endoscopy International Open)
Source: Endoscopy International Open - April 5, 2024 Category: Gastroenterology Authors: Penz, Daniela Pammer, Daniel Waldmann, Elisabeth Asaturi, Arno Szymanska, Aleksrandra Trauner, Michael Ferlitsch, Monika Tags: Original article Source Type: research
A rare case of Gardner syndrome in an African adult male: A case report
Key Clinical MessageGardner's syndrome with the complete manifestation of colonic and extracolonic features is uncommon. Therefore, every clinician should view extracolonic features with a high index of suspicion. This may be key to early diagnosis, definitive management in these patients and importantly, helps prevent malignant transformation of existing colonic polyps. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 4, 2024 Category: General Medicine Authors: Olusegun I. Olaopa,
Adedamola A. Dada,
Oluwafunmilayo Y. Soneye,
Oluwadamilare Iyapo,
Taofeek A. Akinniyi,
Akinyele O. Adisa,
Kehinde K. Kanmodi,
Adedolapo O. Olaopa,
Christian I. Emeka,
Imudia D. Ehanire,
Modupe O. Coker Tags: CASE REPORT Source Type: research
Prevalence and predictive factors of colorectal sessile serrated lesions in younger individuals
Conclusion SSLs are not uncommon among younger individuals. Moreover, diligent effort and expertise are of paramount importance in SSL detection. Future studies should explore the clinical significance of SSLs in individuals of younger age. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Endoscopy)
Source: Endoscopy - April 4, 2024 Category: Gastroenterology Authors: Yeh, Jen-Hao Lin, Chih-Wen Hsiao, Po-Jen Perng, Daw-Shyong Chen, Jen-Chieh Hung, Kuo-Tung Hsu, Chia-Chang Chen, Chia-Chi Liu, Yu-Peng Lee, Yi-Chia Wang, Jaw-Yuan Tags: Original article Source Type: research
Cirrhosis and Portal Hypertension Worsen Bowel Preparation for Screening Colonoscopy
CONCLUSIONS: Patients with cirrhosis have worse BBPS scores and longer cecal intubation times. Nonobese cirrhotic patients additionally have a lower polyp detection rate. Portal hypertension complications were associated with worsened preparation quality and longer cecal intubation times. Each incremental increase in MELD score lengthened cecal intubation time. These findings support a more aggressive bowel preparation strategy for patients with cirrhosis, especially patients with severe disease or portal hypertension complications.PMID:38567898 | DOI:10.1097/MCG.0000000000001990 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - April 3, 2024 Category: Cancer & Oncology Authors: Benjamin Gow-Lee John Gaumnitz Muatassem Alsadhan Gauri Garg Linda Amoafo Yue Zhang John Fang Eduardo Rodriguez Source Type: research
Plain computed tomography for differentiating neoplastic and non-neoplastic pedunculated gallbladder polyps
CONCLUSIONS: PGPs detected using plain CT had a high probability of being NPs. Plain CT is therefore considered to be useful for differentiating NPs from non-NPs.PMID:38569912 | DOI:10.2169/internalmedicine.2760-23 (Source: Internal Medicine)
Source: Internal Medicine - April 3, 2024 Category: Internal Medicine Authors: Fumisato Kozakai Takahisa Ogawa Toshitaka Sakai Shinsuke Koshita Yoshihide Kanno Hiroaki Kusunose Keisuke Yonamine Kazuaki Miyamoto Haruka Okano Yuto Matsuoka Kento Hosokawa Hidehito Sumiya Reiji Sugita Kei Ito Source Type: research
Cirrhosis and Portal Hypertension Worsen Bowel Preparation for Screening Colonoscopy
CONCLUSIONS: Patients with cirrhosis have worse BBPS scores and longer cecal intubation times. Nonobese cirrhotic patients additionally have a lower polyp detection rate. Portal hypertension complications were associated with worsened preparation quality and longer cecal intubation times. Each incremental increase in MELD score lengthened cecal intubation time. These findings support a more aggressive bowel preparation strategy for patients with cirrhosis, especially patients with severe disease or portal hypertension complications.PMID:38567898 | DOI:10.1097/MCG.0000000000001990 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - April 3, 2024 Category: Cancer & Oncology Authors: Benjamin Gow-Lee John Gaumnitz Muatassem Alsadhan Gauri Garg Linda Amoafo Yue Zhang John Fang Eduardo Rodriguez Source Type: research
Plain computed tomography for differentiating neoplastic and non-neoplastic pedunculated gallbladder polyps
CONCLUSIONS: PGPs detected using plain CT had a high probability of being NPs. Plain CT is therefore considered to be useful for differentiating NPs from non-NPs.PMID:38569912 | DOI:10.2169/internalmedicine.2760-23 (Source: Internal Medicine)
Source: Internal Medicine - April 3, 2024 Category: Internal Medicine Authors: Fumisato Kozakai Takahisa Ogawa Toshitaka Sakai Shinsuke Koshita Yoshihide Kanno Hiroaki Kusunose Keisuke Yonamine Kazuaki Miyamoto Haruka Okano Yuto Matsuoka Kento Hosokawa Hidehito Sumiya Reiji Sugita Kei Ito Source Type: research
