Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology
CONCLUSION: Novel BMs such as Gal10 from serum EVs reflect disease pathophysiology in BA and may represent a new target for liquid biopsy approaches.PMID:38551536 | DOI:10.1016/j.jaci.2023.12.030 (Source: Genomics Proteomics ...)
Source: Genomics Proteomics ... - March 29, 2024 Category: Genetics & Stem Cells Authors: Hanako Yoshimura Yoshito Takeda Yuya Shirai Makoto Yamamoto Daisuke Nakatsubo Saori Amiya Takatoshi Enomoto Reina Hara Yuichi Adachi Ryuya Edahiro Moto Yaga Kentaro Masuhiro Taro Koba Miho Itoh-Takahashi Mana Nakayama So Takata Yuki Hosono Sho Obata Masay Source Type: research

Multi-scale nested UNet with transformer for colorectal polyp segmentation
CONCLUSIONS: The proposed model produced more accurate polyp segmentation than current methods on four different public and one in-house datasets. Its capability of polyps segmentation in different sizes shows the potential clinical application.PMID:38551396 | DOI:10.1002/acm2.14351 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - March 29, 2024 Category: Physics Authors: Zenan Wang Zhen Liu Jianfeng Yu Yingxin Gao Ming Liu Source Type: research

SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps
CONCLUSION: SerpinB3/B4 expression is upregulated in nasal mucosa of CRSwNP patients. SerpinB3/B4 may play an anti-inflammatory role in CRSwNP by inhibiting the expression of epithelial cell-derived CXCL8/IL-8.PMID:38550710 | PMC:PMC10978078 | DOI:10.1155/2024/8553447 (Source: Cell Research)
Source: Cell Research - March 29, 2024 Category: Cytology Authors: Xiangting Bu Ming Wang Jing Yuan Jing Song Ge Luan Jiaqi Yu Yang Wang Ying Li Chengshuo Wang Luo Zhang Source Type: research

SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps
CONCLUSION: SerpinB3/B4 expression is upregulated in nasal mucosa of CRSwNP patients. SerpinB3/B4 may play an anti-inflammatory role in CRSwNP by inhibiting the expression of epithelial cell-derived CXCL8/IL-8.PMID:38550710 | PMC:PMC10978078 | DOI:10.1155/2024/8553447 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - March 29, 2024 Category: Allergy & Immunology Authors: Xiangting Bu Ming Wang Jing Yuan Jing Song Ge Luan Jiaqi Yu Yang Wang Ying Li Chengshuo Wang Luo Zhang Source Type: research

Breaking the neural code of a cnidarian: Learning principles of neuroscience from the "vulgar" Hydra
Curr Opin Neurobiol. 2024 Mar 28;86:102869. doi: 10.1016/j.conb.2024.102869. Online ahead of print.ABSTRACTThe cnidarian Hydra vulgaris is a small polyp with a nervous system of few hundred neurons belonging to a dozen cell types, organized in two nerve nets without cephalization or ganglia. Using this simple neural "chassis", Hydra can maintain a stable repertoire of behaviors, even performing complex fixed-action patterns, such as somersaulting and feeding. The ability to image the activity of Hydra's entire neural and muscle tissue has revealed that Hydra's nerve nets are divided into coactive ensembles of neurons, asso...
Source: Current Opinion in Neurobiology - March 29, 2024 Category: Neurology Authors: Rafael Yuste Source Type: research

Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology
CONCLUSION: Novel BMs such as Gal10 from serum EVs reflect disease pathophysiology in BA and may represent a new target for liquid biopsy approaches.PMID:38551536 | DOI:10.1016/j.jaci.2023.12.030 (Source: Genomics Proteomics ...)
Source: Genomics Proteomics ... - March 29, 2024 Category: Genetics & Stem Cells Authors: Hanako Yoshimura Yoshito Takeda Yuya Shirai Makoto Yamamoto Daisuke Nakatsubo Saori Amiya Takatoshi Enomoto Reina Hara Yuichi Adachi Ryuya Edahiro Moto Yaga Kentaro Masuhiro Taro Koba Miho Itoh-Takahashi Mana Nakayama So Takata Yuki Hosono Sho Obata Masay Source Type: research

Multi-scale nested UNet with transformer for colorectal polyp segmentation
CONCLUSIONS: The proposed model produced more accurate polyp segmentation than current methods on four different public and one in-house datasets. Its capability of polyps segmentation in different sizes shows the potential clinical application.PMID:38551396 | DOI:10.1002/acm2.14351 (Source: Journal of Applied Clinical Medical Physics)
Source: Journal of Applied Clinical Medical Physics - March 29, 2024 Category: Physics Authors: Zenan Wang Zhen Liu Jianfeng Yu Yingxin Gao Ming Liu Source Type: research

SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps
CONCLUSION: SerpinB3/B4 expression is upregulated in nasal mucosa of CRSwNP patients. SerpinB3/B4 may play an anti-inflammatory role in CRSwNP by inhibiting the expression of epithelial cell-derived CXCL8/IL-8.PMID:38550710 | PMC:PMC10978078 | DOI:10.1155/2024/8553447 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - March 29, 2024 Category: Allergy & Immunology Authors: Xiangting Bu Ming Wang Jing Yuan Jing Song Ge Luan Jiaqi Yu Yang Wang Ying Li Chengshuo Wang Luo Zhang Source Type: research

Breaking the neural code of a cnidarian: Learning principles of neuroscience from the "vulgar" Hydra
Curr Opin Neurobiol. 2024 Mar 28;86:102869. doi: 10.1016/j.conb.2024.102869. Online ahead of print.ABSTRACTThe cnidarian Hydra vulgaris is a small polyp with a nervous system of few hundred neurons belonging to a dozen cell types, organized in two nerve nets without cephalization or ganglia. Using this simple neural "chassis", Hydra can maintain a stable repertoire of behaviors, even performing complex fixed-action patterns, such as somersaulting and feeding. The ability to image the activity of Hydra's entire neural and muscle tissue has revealed that Hydra's nerve nets are divided into coactive ensembles of neurons, asso...
Source: Current Opinion in Neurobiology - March 29, 2024 Category: Neurology Authors: Rafael Yuste Source Type: research

Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology
CONCLUSION: Novel BMs such as Gal10 from serum EVs reflect disease pathophysiology in BA and may represent a new target for liquid biopsy approaches.PMID:38551536 | DOI:10.1016/j.jaci.2023.12.030 (Source: Genomics Proteomics ...)
Source: Genomics Proteomics ... - March 29, 2024 Category: Genetics & Stem Cells Authors: Hanako Yoshimura Yoshito Takeda Yuya Shirai Makoto Yamamoto Daisuke Nakatsubo Saori Amiya Takatoshi Enomoto Reina Hara Yuichi Adachi Ryuya Edahiro Moto Yaga Kentaro Masuhiro Taro Koba Miho Itoh-Takahashi Mana Nakayama So Takata Yuki Hosono Sho Obata Masay Source Type: research

SerpinB3/B4 Abates Epithelial Cell-Derived CXCL8/IL-8 Expression in Chronic Rhinosinusitis with Nasal Polyps
CONCLUSION: SerpinB3/B4 expression is upregulated in nasal mucosa of CRSwNP patients. SerpinB3/B4 may play an anti-inflammatory role in CRSwNP by inhibiting the expression of epithelial cell-derived CXCL8/IL-8.PMID:38550710 | PMC:PMC10978078 | DOI:10.1155/2024/8553447 (Source: Journal of Immunology Research)
Source: Journal of Immunology Research - March 29, 2024 Category: Allergy & Immunology Authors: Xiangting Bu Ming Wang Jing Yuan Jing Song Ge Luan Jiaqi Yu Yang Wang Ying Li Chengshuo Wang Luo Zhang Source Type: research

Breaking the neural code of a cnidarian: Learning principles of neuroscience from the "vulgar" Hydra
Curr Opin Neurobiol. 2024 Mar 28;86:102869. doi: 10.1016/j.conb.2024.102869. Online ahead of print.ABSTRACTThe cnidarian Hydra vulgaris is a small polyp with a nervous system of few hundred neurons belonging to a dozen cell types, organized in two nerve nets without cephalization or ganglia. Using this simple neural "chassis", Hydra can maintain a stable repertoire of behaviors, even performing complex fixed-action patterns, such as somersaulting and feeding. The ability to image the activity of Hydra's entire neural and muscle tissue has revealed that Hydra's nerve nets are divided into coactive ensembles of neurons, asso...
Source: Current Opinion in Neurobiology - March 29, 2024 Category: Neurology Authors: Rafael Yuste Source Type: research